691 results on '"Brown, Eric J."'
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2. Improved detection of DNA replication fork-associated proteins
3. Combination ATR and PARP Inhibitor (CAPRI): A phase 2 study of ceralasertib plus olaparib in patients with recurrent, platinum-sensitive epithelial ovarian cancer (cohort A).
4. CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models
5. The DNA Damage Response: Roles in Cancer Etiology and Treatment
6. Understanding the microstructure and mechanical properties of Ti-6Al-4V and Inconel 718 alloys manufactured by Laser Engineered Net Shaping
7. Data from Combination ATR (ceralasertib) and PARP (olaparib) Inhibitor (CAPRI) Trial in Acquired PARP Inhibitor–Resistant Homologous Recombination–Deficient Ovarian Cancer
8. Supplementary Table 1 from Combination ATR (ceralasertib) and PARP (olaparib) Inhibitor (CAPRI) Trial in Acquired PARP Inhibitor–Resistant Homologous Recombination–Deficient Ovarian Cancer
9. Supplementary Figure 1 from Combination ATR (ceralasertib) and PARP (olaparib) Inhibitor (CAPRI) Trial in Acquired PARP Inhibitor–Resistant Homologous Recombination–Deficient Ovarian Cancer
10. Clinical trial protocol1 from Combination ATR (ceralasertib) and PARP (olaparib) Inhibitor (CAPRI) Trial in Acquired PARP Inhibitor–Resistant Homologous Recombination–Deficient Ovarian Cancer
11. Host-derived fatty acids activate type VII secretion in Staphylococcus aureus
12. Guidelines for the use and interpretation of assays for monitoring autophagy.
13. Role of the WASP Family Proteins for Mycobacterium Marinum Actin Tail Formation
14. Combination ATR (ceralasertib) and PARP (olaparib) Inhibitor (CAPRI) Trial in Acquired PARP Inhibitor–Resistant Homologous Recombination–Deficient Ovarian Cancer
15. Abstract 6177: ATRN-119 and ATRN-W1051: Novel and potentially well tolerated ATR and WEE1 inhibitors for targeted cancer treatment
16. Abstract 1133: A B7-H4 targeting antibody-drug conjugate shows anti-tumor activity in PARPi and platinum resistant cancers with B7-H4 expression
17. The Ubiquitin-Related Protein PLIC-1 Regulates Heterotrimeric G Protein Function through Association with Gβγ
18. Germline Transmission and Tissue-Specific Expression of Transgenes Delivered by Lentiviral Vectors
19. Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models
20. A Mycobacterium ESX-1–Secreted Virulence Factor with Unique Requirements for Export
21. Role of Cholesterol in Formation and Function of a Signaling Complex Involving αvβ3, Integrin-Associated Protein (CD47), and Heterotrimeric G Proteins
22. A Molecular Mechanism of Integrin Crosstalk: α vβ 3 Suppression of Calcium/Calmodulin-Dependent Protein Kinase II Regulates α 5β 1 Function
23. A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion
24. Fatigue crack growth behavior and microstructural mechanisms in Ti-6Al-4V manufactured by laser engineered net shaping
25. Mycobacterium marinum escapes from phagosomes and is propelled by actin-based motility
26. Requirement for kasB in Mycobacterium mycolic acid biosynthesis, cell wall impermeability and intracellular survival: implications for therapy
27. A Role for the Actin-Bundling Protein L-Plastin in the Regulation of Leukocyte Integrin Function
28. A Role for the αvβ3 Integrin in the Transmigration of Monocytes
29. Role for a Glycan Phosphoinositol Anchor in Fcγ Receptor Synergy
30. Supplementary Table 1 from Combining ATR Suppression with Oncogenic Ras Synergistically Increases Genomic Instability, Causing Synthetic Lethality or Tumorigenesis in a Dosage-Dependent Manner
31. Data from Combining ATR Suppression with Oncogenic Ras Synergistically Increases Genomic Instability, Causing Synthetic Lethality or Tumorigenesis in a Dosage-Dependent Manner
32. Supplementary Figures 1-5 from Combining ATR Suppression with Oncogenic Ras Synergistically Increases Genomic Instability, Causing Synthetic Lethality or Tumorigenesis in a Dosage-Dependent Manner
33. Decreased Resistance to Bacterial Infection and Granulocyte Defects in IAP-Deficient Mice
34. Thrombospondin Modulates α v β 3 Function through Integrin-Associated Protein
35. Integrin-Associated Protein Immunoglobulin Domain Is Necessary for Efficient Vitronectin Bead Binding
36. G6PD-mediated increase in de novo NADP + biosynthesis promotes antioxidant defense and tumor metastasis
37. Global Gene Expression of Methicillin-resistant Staphylococcus aureus USA300 During Human and Mouse Infection
38. Identifying Potential Therapeutic Targets of Methicillin-resistant Staphylococcus aureus Through in Vivo Proteomic Analysis
39. A Macrophage Invasion Mechanism of Pathogenic Mycobacteria
40. Tim-Tipin Dysfunction Creates an Indispensible Reliance on the ATR-Chk1 Pathway for Continued DNA Synthesis
41. HIF2α Inhibition Promotes p53 Pathway Activity, Tumor Cell Death, and Radiation Responses
42. The Art of Making an Exit
43. Role for Lysosomal Enzyme β-Hexosaminidase in the Control of Mycobacteria Infection
44. Acute Postnatal Ablation of Hif-2α Results in Anemia
45. C-Terminal Signal Sequence Promotes Virulence Factor Secretion in Mycobacterium tuberculosis
46. Induction of IL19 expression through JNK and cGAS-STING modulates DNA damage–induced cytokine production
47. The Tumor Suppressor Menin Regulates Hematopoiesis and Myeloid Transformation by Influencing Hox Gene Expression
48. Signal Transduction from Leukocyte Integrins
49. Matrix Receptors of Myeloid Cells
50. Signal Transduction Through a Novel Phagocyte Integrin
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