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1. Native valve Proteus mirabilis endocarditis: successful treatment of a rare entity formulated by in vitro synergy antibiotic testing.

Author

Brotzki CR, Mergenhagen KA, Bulman ZP, Tsuji BT, and Berenson CS

Subjects
Aortic Valve diagnostic imaging, Drug Synergism, Drug Therapy, Combination, Echocardiography, Endocarditis, Bacterial diagnostic imaging, Humans, In Vitro Techniques, Male, Microbial Sensitivity Tests, Middle Aged, Proteus Infections diagnostic imaging, Proteus mirabilis, Anti-Bacterial Agents therapeutic use, Ceftriaxone therapeutic use, Endocarditis, Bacterial drug therapy, Gentamicins therapeutic use, Proteus Infections drug therapy
Abstract

Infective endocarditis caused by Proteus mirabilis is a rare and poorly reported disease, with no well-defined effective antibiotic regimen. Here, we present a case of P. mirabilis aortic valve endocarditis. We reviewed prior cases and treatment regimens, and devised effective treatment, which was guided by in vitro sensitivity and synergy testing on the pathogen. Our patient survived without complications or the need for a surgical intervention., Competing Interests: Conflicts of Interest: None declared., (2016 BMJ Publishing Group Ltd.)

Published
2016
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