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1. Impact d’une initiation différée du méthotrexate d’un mois sur l’activité clinique et la progression structurale de la polyarthrite rhumatoïde à 1 an

Author

Than, T., primary, Dernis, E., additional, Schaeverbeke, T., additional, Brocq, O., additional, Fautrel, B., additional, Roux, C., additional, Bustamente, L., additional, Vittecoq, O., additional, Lukas, C., additional, Daien, C., additional, Lioté, F., additional, Soubrier, M., additional, Gaujoux-Viala, C., additional, Constantin, A., additional, Saraux, A., additional, Salliot, C., additional, Goëb, V., additional, Remy-Moulard, A., additional, Huguet, H., additional, Picot, M.C., additional, and Morel, J., additional

Published
2023
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2. Comparaison de la réponse humorale au vaccin pneumococcique conjugué et au vaccin pneumococcique polysaccharidique chez les patients atteints de PR sous abatacept : étude VACINA

Author

Morel, J., primary, Brocq, O., additional, Gaujoux-Viala, C., additional, Lassoued, S., additional, Dernis, E., additional, Richez, C., additional, Amico, M., additional, Lukas, C., additional, Constantin, A., additional, Daien, C., additional, and Duflos, C., additional

Published
2023
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3. Évaluation de la pneumopathie interstitielle des patients atteints de polyarthrite rhumatoïde traités par inhibiteurs de JAK : étude observationnelle multicentrique nationale à partir du registre MAJIK-SFR

Author

Triboulet, F., primary, Juge, P.A., additional, Truchetet, M.E., additional, Pham, T., additional, Roux, N., additional, Flipo, R.M., additional, Leské, C., additional, Roux, C., additional, Seror, R., additional, Basch, A., additional, Brocq, O., additional, Chazerain, P., additional, Coury, F., additional, Damade, R., additional, Dernis, E., additional, Gottenberg, J.E., additional, Ramon, A., additional, Ruyssen-Witrand, A., additional, Salmon, J.H., additional, Shipley, E., additional, Tournadre, A., additional, Prati, C., additional, Dieudé, P., additional, and Avouac, J., additional

Published
2023
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5. POS0630 ANTIDRUG ANTIBODIES ARE NEGATIVELY ASSOCIATED WITH RESPONSE TO BIOLOGICAL DRUGS IN PATIENTS WITH RHEUMATOID ARTHRITIS: RESULTS OF THE ABIRISK STUDY

Author

Bitoun, S., primary, Hässler, S., additional, Ternant, D., additional, Szely, N., additional, Gleizes, A., additional, Hacein Bey, S., additional, Richez, C., additional, Soubrier, M., additional, Avouac, J., additional, Brocq, O., additional, Sellam, J., additional, De Vries, N., additional, Huizinga, T., additional, Jury, E., additional, Manson, J., additional, Mauri, C., additional, Matucci, A., additional, Mulleman, D., additional, Pallardy, M., additional, Bröet, P., additional, and Mariette, X., additional

Published
2023
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6. POS1068 HUMORAL IMMUNE RESPONSE TO 13 VALENT-CONJUGATE AND 23-VALENT POLYSACCHARIDE PNEUMOCOCCAL VACCINES IN RA PATIENTS TREATED WITH ABATACEPT: RESULTS OF THE OPEN RANDOMIZED CONTROLLED TRIAL VACINA (VACCINATION AGAINST PNEUMOCOCCAL IN NAÏVE ABATACEPT RHEUMATOID ARTHRITIS PATIENTS)

Author

Morel, J., primary, Brocq, O., additional, Gaujoux-Viala, C., additional, Constantin, A., additional, Lassoued, S., additional, Dernis, E., additional, Richez, C., additional, Lukas, C., additional, Daien, C., additional, and Duflos, C., additional

Published
2023
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7. Les anticorps anti-biomédicament sont négativement associés à la réponse au traitement par anti-TNF monoclonaux et anti-IL-6 récepteur dans la polyarthrite rhumatoïde : les résultats de l’étude ABIRISK

Author

Bitoun, S., primary, Hassler, S., additional, Szely, N., additional, Gleizes, A., additional, Hacein Bey, S., additional, Richez, C., additional, Soubrier, M., additional, Avouac, J., additional, Brocq, O., additional, Sellam, J., additional, De Vries, N., additional, Huizinga, T.W., additional, Jury, E., additional, Manson, J., additional, Mauri, C., additional, Mattuci, A., additional, Bröet, P., additional, and Mariette, X., additional

Published
2022
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8. Des rappels SMS et mails augmentent-ils le taux de vaccination contre la grippe saisonnière chez les PR sous biothérapies ? Essai contrôlé randomisé niché dans le registre ART

Author

Seror, R., primary, Baron, G., additional, Belkhir, R., additional, Miconnet, S., additional, Soubrier, M., additional, Hostachy, C., additional, Thevenot, P., additional, Basch, A., additional, Truchetet, M.E., additional, Claudepierre, P., additional, Dernis, E., additional, Marotte, H., additional, Flipo, R.M., additional, Brocq, O., additional, Morel, J., additional, Fautrel, B., additional, Salliot, C., additional, Saraux, A., additional, Leské, C., additional, Hamamouche, N., additional, Shaeverbeke, T., additional, Ravaud, P., additional, Mariette, X., additional, and Ruyssen-Witrand, A., additional

Published
2022
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10. POS0700 IMPACT OF DELAYING INITIATION OF METHOTREXATE BY 1 MONTH ON THE OUTCOME OF RHEUMATOID ARTHRITIS AT 1 YEAR

Author

Than, T., primary, Dernis, E., additional, Breuil, V., additional, Schaeverbeke, T., additional, Brocq, O., additional, Fautrel, B., additional, Salliot, C., additional, Vittecoq, O., additional, Mariette, X., additional, Lioté, F., additional, Lassoued, S., additional, Gaujoux-Viala, C., additional, Soubrier, M., additional, Saraix, A., additional, Constantin, A., additional, Goeb, V., additional, Daien, C., additional, Remy-Moulard, A., additional, Huguet, H., additional, Lukas, C., additional, Picot, M. C., additional, and Morel, J., additional

Published
2022
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13. Tolérance de la vaccination contre le SRAS-CoV-2 chez les patients atteints de maladies rhumatologiques inflammatoires/auto-immunes : résultats du registre EULAR-COVAX chez 5121 patients

Author

Mariette, X., primary, Lawson-Tovey, S., additional, Hachulla, E., additional, Veillard, E., additional, Trefond, L., additional, Soubrier, M., additional, Roux, N., additional, Brocq, O., additional, Durez, P., additional, Goulenok, T., additional, Gossec, L., additional, Strakova, E., additional, Burmester, G.R., additional, Kübra, Y.G., additional, Gomez, P.J.A., additional, Zepa, J., additional, Hyrich, K., additional, Cunha, M.M., additional, Mosca, M., additional, Cornalba, M., additional, Mateus, E., additional, Carmona, L., additional, Rodrigues, A., additional, Raffeiner, B., additional, Conway, R., additional, Strangfeld, A., additional, Bijlsma, H., additional, McInnes, I.B., additional, and Machado, P., additional

Published
2021
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17. PC.27 - Facteurs associés aux formes sévères de spondyloarthropathie axiale : résultats de l’étude nationale multicentrique Bamboospine

Author

Gross, J., Singvongsa, S., Molto, A., Etcheto, A., Allanore, Y., Balandraud, N., Boissier, M.C., Boumier, P., Brocq, O., Claudepierre, P., Devauchelle Pensec, V., Fautrel, B., Gaudin, P., Le Goff, B., Loeuille, D., Pavy, S., Richette, P., Ruyssen-Witrand, A., Saint Marcoux, B., Sellam, J., Soubrier, M., Thomas, T., Vittecoq, O., Wendling, D., Dougados, M., and Miceli Richard, C.

Published
2016
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18. LB0002 COVID-19 VACCINE SAFETY IN PATIENTS WITH RHEUMATIC AND MUSCULOSKELETAL DISEASE

Author

Machado, P. M., primary, Lawson-Tovey, S., additional, Hyrich, K., additional, Carmona, L., additional, Gossec, L., additional, Mateus, E., additional, Strangfeld, A., additional, Raffeiner, B., additional, Goulenok, T., additional, Brocq, O., additional, Cornalba, M., additional, Gómez-Puerta, J. A., additional, Veillard, E., additional, Trefond, L., additional, Gottenberg, J. E., additional, Henry, J., additional, Durez, P., additional, Burmester, G. R., additional, Mosca, M., additional, Hachulla, E., additional, Bijlsma, H., additional, McInnes, I., additional, and Mariette, X., additional

Published
2021
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19. Impact de l’épidémie à COVID-19 sur la prise en charge de la PR en France : données issues de la e-cohorte ART-SFR

Author

Ruyssen-Witrand, A., primary, Boudali, Y., additional, Cantagrel, A., additional, Soubrier, M., additional, Morel, J., additional, Brocq, O., additional, Fautrel, B., additional, Salliot, C., additional, Roux, C., additional, Saraux, A., additional, Basch, A., additional, Truchetet, M.E., additional, Marotte, H., additional, Dernis, E., additional, Claudepierre, P., additional, Flipo, R.M., additional, Gottenberg, J.E., additional, Ravaud, P., additional, Mariette, X., additional, and Seror, R., additional

Published
2020
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21. AB0310 TROUGH CONCENTRATION AND ESTIMATED CLEARANCE CAN DETECT IMMUNOGENICITY TO ADALIMUMAB IN RA PATIENTS: A PROSPECTIVE LONGITUDINAL MULTICENTRE STUDY

Author

Ternant, D., primary, Elhasnaoui, J., additional, Szely, N., additional, Hacein-Bey, S., additional, Gleizes, A., additional, Richez, C., additional, Manson, J., additional, Soubrier, M., additional, Brocq, O., additional, Avouac, J., additional, Fogdell-Hahn, A., additional, Dönnes, P., additional, Paintaud, G., additional, Desvignes, C., additional, Deisenhammer, F., additional, Spindeldreher, S., additional, Pallardy, M., additional, Mariette, X., additional, and Mulleman, D., additional

Published
2020
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22. The comparative responsiveness of Hospital Universitario Princesa Index and other composite indices for assessing rheumatoid arthritis activity

Author

Gonzalez-Alvaro, Isidoro, Castrejon, Isabel, Carmona, Loreto, Dougados, M., Huizinga, T., Abu Shakra, M., Alberts, A., Alperi Lopez, M., Amital, H., Aringer, M., Aslanidis, S., Berenbaum, F., Bijlsma, H., Blanco Garcia, F. J., Bliddal, H., Borofsky, M., Brocq, O., Buldakov, S., Cantini, F., Carreno Perez, L., Chahade, W., Ciconelli, R., Codreanu, C., Dahlqvist, S. R., Damjanov, N., Diamantopoulos, A., Dimdina, L., Dimic, A., Dorokhov, A., Dubikov, A., Fadienko, G., Fano, N., Ferreira, G., Gabrielli, A., Gaffney, K., Gaudin, P., Gerlag, D. M., Gerli, R., Goncalves, C. R., Hansen, M. S., Hanvivadhanakul, P., Hoili, C., Hou, A., Hunter, J., Ilic, T., Ionescu, R., Kaine, J., Kakurina, N., Kamalova, R., Kelly, T., Knyazeva, L., Krumina, L., Kurthen, R., Lagrone, R. P., Lapadula, G., Lavrentjevs, V, Lawson, J. G., Lazic, Z., Lejnieks, A., Levy, Y., Lexberg, A., Mader, R., Mariette, X., Markovits, D., Mola, Martin E., Maugars, Y., Guarch, Maymo J., Mazurov, V., I, Mikkelsen, K., Vergles, Morovic J., Nabizadeh, S., Nanagara, R., Nasonov, E. L., Sarabia, Navarro F., Neumann, T., Novak, S., Olech, E., Oza, M., Paran, D., Parsik, E., Pegram, S., Suarez, Pombo M., Popova, T., Puechal, X., Raja, N., Ridley, D., Rosner, I, Rubbert-Roth, A., Rudin, A., Saraux, A., Saulite-Kandevica, D., Settas, L., Sfikakis, P., Sheeran, T., Sizikov, A., Stamenkovic, D., Stefanovic, D., Stolow, J. B., Tan, A. L., Tebib, J., Tishler, M., Tony, H. P., Troum, O. M., Uaratanawong, S., Ucar Angulo, E., Valenzuela, G., van der Laken, K., Van Laar, J., van Riel, P. L. C. M., Vasilopoulos, D., Veldi, T., Vinogradova, I, Vosse, D., Wassenberg, S., Weidmann, C., Weitz, M., Wollenhaupt, J., Xavier, R., Yakupova, S., Zagar, I, Zavgorodnaja, T., Zemerova, E., Zisman, D., Zonova, E., Camona, Loreto, Abasolo Alcazar, L., Alegre de Miguel, C., Andreu Sanchez, J. L., Aragon Diez, A., Balsa Criado, A., Batlle Gualda, E., Belmonte Serrano, M. A., Beltran Audera, J., Beltran Fabregat, J., Bonilla Hernan, G., Caro Fernandez, N., Casado, E., Cebrian Mendez, L., Corteguera Coro, M., Cuadra Diaz, J. L., Cuesta, E., Fiter Areste, J., Freire Gonzalez, M., Galindo Izquierdo, M., Garcia Meijide, J. A., Garcia Gomez, M. C., Gimenez Ubeda, E., Gomez Centeno, E., Gomez Vaquero, C., Gonzalez Fernandez, M. J., Gonzalez Gomez, M. L., Gonzalez Hernandez, T., Gonzalez-Alvaro, I, Gonzalez-Montagut Gomez, C., Grandal Delgado, Y., Gratacos Masmitja, J., Hernandez del Rio, A., Instxaurbe, A. R., Irigoyen Oyarzabal, M., V, Jimenez Palop, M., Juan Mas, A., Judez Navarro, E., Larrosa Padro, M., Lopez Longo, F. J., Loza Santamaria, E., Maese Manzano, J., Manero Ruiz, F. J., Mateo Bernardo, I, Mayordomo Gonzalez, L., Mazzucheli, R., Medrano San Idelfonso, M., Naranjo Hernandez, A., Pecondon Espanol, A., Peiro Callizo, E., Quiros Donate, J., Ramos Lopez, P., Rivera Redondo, J., Rodriguez Gomez, M., Rodriguez Lopez, M., Rosello Pardo, R., Sampedro Alvarez, J., Sanmarti Sala, R., Rey Rey, Santos J., Tena Marsa, X., Tenorio Martin, M., Torres Martin, M. C., Urena Garnica, I, Valdazo de Diego, J. P., Valls, M., Villaverde Garcia, V., Zarco Montejo, P., Zubieta Tabernero, J., Balsa, Alejandro, Sanmarti, Raimon, Cabezas, J. A., Cantalejo, M., Chamizo, E., Ciruelo, E., Corrales, A., Cruz, A., Diaz, C., Fiter, J., Freire, M. M., Galindo, M., Garcia de Vicuna, M. R., Gelman, S. M., Gonzalez Crespo, R., Gonzalez Fernandez, C., Gracia, A., Granados, J., Guzman, M. A., Irigoyen, M., V, Juan, A., Juanola, X., Laiz, A., Manero, F. J., Martinez, A., Martinez, F., Mata, C., Maymo, J., Navarro, F. J., Peiro, E., Perez, F., Perez, G., Perez, M., Pujol, M., Quiros, J., Ribas, B., Riera, M., Rivera, J., Rodriguez, J. M., Rosello, R., Tenorio, M., Toyos, F. J., ACT-RAY Study Grp, PROAR Study Grp, EMECAR Study Grp, Interne Geneeskunde, MUMC+: MA Reumatologie (9), and RS: CAPHRI - R3 - Functioning, Participating and Rehabilitation

Subjects
Male, medicine.medical_specialty, Science, humanos, Severity of Illness Index, RECOMMENDATIONS, VALIDATION, VARIABLES, ensayos clínicos como asunto, Arthritis, Rheumatoid, Cohort Studies, Internal medicine, Linear regression, Severity of illness, medicine, Humans, índice de gravedad de la enfermedad, estudios de cohortes, mediana edad, Clinical Trials as Topic, DISEASE-ACTIVITY MEASURES, Multidisciplinary, SCORES, business.industry, Arthritis, resultado del tratamiento, modelos lineales, Secondary data, Gold standard (test), Middle Aged, medicine.disease, Clinical trial, Treatment Outcome, Rheumatoid arthritis, Antirheumatic Agents, Cohort, Linear Models, Medicine, Female, GENDER, business, antirreumáticos, artritis, Cohort study
Abstract

Objective To evaluate the responsiveness in terms of correlation of the Hospital Universitario La Princesa Index (HUPI) comparatively to the traditional composite indices used to assess disease activity in rheumatoid arthritis (RA), and to compare the performance of HUPI-based response criteria with that of the EULAR response criteria. Methods Secondary data analysis from the following studies: ACT-RAY (clinical trial), PROAR (early RA cohort) and EMECAR (pre-biologic era long term RA cohort). Responsiveness was evaluated by: 1) comparing change from baseline (Delta) of HUPI with Delta in other scores by calculating correlation coefficients; 2) calculating standardised effect sizes. The accuracy of response by HUPI and by EULAR criteria was analyzed using linear regressions in which the dependent variable was change in global assessment by physician (Delta GDA-Phy). Results Delta HUPI correlation with change in all other indices ranged from 0.387 to 0.791); HUPI's standardized effect size was larger than those from the other indices in each database used. In ACT-RAY, depending on visit, between 65 and 80% of patients were equally classified by HUPI and EULAR response criteria. However, HUPI criteria were slightly more stringent, with higher percentage of patients classified as non-responder, especially at early visits. HUPI response criteria showed a slightly higher accuracy than EULAR response criteria when using Delta GDA-Phy as gold standard. Conclusion HUPI shows good responsiveness in terms of correlation in each studied scenario (clinical trial, early RA cohort, and established RA cohort). Response criteria by HUPI seem more stringent than EULAR's., Our study was supported by grants RD16/0012/0011 and PI14/00442 from the Ministerio de Economia y Competitividad (Instituto de Salud Carlos III; Spain) and cofunded by the Fondo Europeo de Desarrollo Regional (FEDER). Data from ACT-RAY clinical trial were kindly provided by Hoffmann-La Roche Ltd. No financial support was received from Hoffmann-La Roche Ltd Data from EMECAR and PROAR cohorts were provided by the Spanish Society of Rheumatology. No financial support was received from the Spanish Society of Rheumatology. None of these institutions played any role in the analysis or interpretation of data, nor were they involved in the writing of the manuscript. Roche and Sociedad Espanola de Reumatologia were involved in the collection of data from ACT-RAY, and EMECAR and PROAR, respectively. However, these funders had no role in study design, analysis, decision to publish, or preparation of the manuscript.

Published
2019

32. Facteurs associés aux formes sévères de spondyloarthropathie axiale : résultats de l’étude nationale multicentrique Bamboospine

Author

Gross, J., primary, Singvongsa, S., additional, Molto, A., additional, Etcheto, A., additional, Allanore, Y., additional, Balandraud, N., additional, Boissier, M.C., additional, Boumier, P., additional, Brocq, O., additional, Claudepierre, P., additional, Devauchelle Pensec, V., additional, Fautrel, B., additional, Gaudin, P., additional, Le Goff, B., additional, Loeuille, D., additional, Pavy, S., additional, Richette, P., additional, Ruyssen-Witrand, A., additional, Saint Marcoux, B., additional, Sellam, J., additional, Soubrier, M., additional, Thomas, T., additional, Vittecoq, O., additional, Wendling, D., additional, Dougados, M., additional, and Miceli Richard, C., additional

Published
2016
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34. FRI0155 Fifty Percent of Patients Who Tapered TNF-Blockers while in Stable Remission Are Able To Maintain A Tapered Regimen at 3 Year: Long Term Follow-Up Extension of The Strass Trial

Author

Sigaux, J., primary, Bailly, F., additional, Gossec, L., additional, Alfaiate, T., additional, Gandjbakhch, F., additional, Foltz, V., additional, Morel, J., additional, Dernis, E., additional, Gaudin, P., additional, Brocq, O., additional, Berthelot, J.-M., additional, Balblanc, J.-C., additional, Mariette, X., additional, Tubach, F., additional, and Fautrel, B., additional

Published
2016
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37. THU0151 Effects of Tnfα-Blockers Tapering on Occurrence of Patient-Perceived Flares in Rheumatoid Arthritis: A Subanalysis of Strass

Author

Danré, A., primary, Gossec, L., additional, Pham, T., additional, Morel, J., additional, Alfaiate, T., additional, Dernis, E., additional, Gaudin, P., additional, Brocq, O., additional, Solau-Gervais, E., additional, Berthelot, J.-M., additional, Balblanc, J.C., additional, Mariette, X., additional, Tubach, F., additional, and Fautrel, B., additional

Published
2014
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38. AB0848 Rituximab treatment for spondyloarthritis. A nationwide series: Data from the air registry

Author

Wendling, D., primary, Dougados, M., additional, Berenbaum, F., additional, Brocq, O., additional, Schaeverbeke, T., additional, Mazieres, B., additional, Marcelli, C., additional, Le Parc, J.-M., additional, Bertin, P., additional, Robin, M., additional, Sibilia, J., additional, Lafforgue, P., additional, Prati, C., additional, Combe, B., additional, and Gottenberg, J.-E., additional

Published
2013
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