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3. Lung Ultrasound in Emergency and Critically Ill Patients: Number of Supervised Exams to Reach Basic Competence

Author

Arbelot, Charlotte, Dexheimer Neto, Felippe Leopoldo, Gao, Yuzhi, Brisson, Hélène, Chunyao, Wang, Lv, Jie, Valente Barbas, Carmen Silvia, Perbet, Sébastien, Prior Caltabellotta, Fabiola, Gay, Frédérick, Deransy, Romain, Lima, Emidio J. S., Cebey, Andres, Monsel, Antoine, Neves, Julio, Zhang, Mao, Bin, Du, An, Youzhong, Malbouisson, Luis, Salluh, Jorge, Constantin, Jean-Michel, Rouby, Jean-Jacques, Biestro, Alberto, Vezinet, Corinne, Garçon, Pierre, El Hadj Kacem, Nabil, Lemesle, Denis, Lucena, Bruno, de Paula Pinto Schettino, Guilherme, Cristovao, Davi, de Tarso Roth Dalcin, Paulo, and Carmona, Maria José Carvalho

Published
2020
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4. Proceedings of Réanimation 2017, the French Intensive Care Society International Congress

Author

Kamilia, Chtara, Regaieg, Kais, Baccouch, Najeh, Chelly, Hedi, Bahloul, Mabrouk, Bouaziz, Mounir, Jendoubi, Ali, Abbes, Ahmed, Belhaouane, Houda, Nasri, Oussama, Jenzri, Layla, Ghedira, Salma, Houissa, Mohamed, Belkadi, Kamal, Harti, Youness, Nsiri, Afak, Khaleq, Khalid, Hamoudi, Driss, Harrar, Rachid, Thieffry, Camille, Wallet, Frédéric, Parmentier-Decrucq, Erika, Favory, Raphaël, Mathieu, Daniel, Poissy, Julien, Lafon, Thomas, Vignon, Philippe, Begot, Emmanuelle, Appert, Alexandra, Hadj, Mathilde, Claverie, Paul, Matt, Morgan, Barraud, Olivier, François, Bruno, Jamoussi, Amira, Jazia, Amira Ben, Marhbène, Takoua, Lakhdhar, Dhouha, Khelil, Jalila Ben, Besbes, Mohamed, Goutay, Julien, Blazejewski, Caroline, Joly-Durand, Isabelle, Pirlet, Isabelle, Weillaert, Marie Pierre, Beague, Sebastien, Aziz, Soufi, Hafiane, Reda, Hattabi, Khalid, Bouhouri, Mohamed Aziz, Hammoudi, Driss, Fadil, Abdelaziz, Harrar, Rachid Al, Zerouali, Khalid, Medhioub, Fatma Kaaniche, Allela, Rania, Algia, Najla Ben, Cherif, Samar, Slaoui, Mohamed Taoufik, Boubia, Souhail, Hafiani, Y., Khaoudi, A., Cherkab, R., Elallam, W., Elkettani, C., Barrou, L., Ridaii, M., Mehdi, Rihi El, Schimpf, Caroline, Mizrahi, Assaf, Pilmis, Benoît, Le Monnier, Alban, Tiercelet, Kelly, Cherin, Mélanie, Bruel, Cédric, Philippart, Francois, Bailly, Sébastien, Lucet, Jc, Lepape, Alain, L’hériteau, François, Aupée, Martine, Bervas, Caroline, Boussat, Sandrine, Berger-Carbonne, Anne, Machut, Anaïs, Savey, Anne, Timsit, Jean-François, Razazi, Keyvan, Rosman, Jérémy, de Prost, Nicolas, Carteaux, Guillaume, Jansen, Chloe, Decousser, Jean Winoc, Brun-Buisson, Christian, Dessap, Armand Mekontso, M’rad, Aymen, Ouali, Zouhour, Barghouth, Manel, Kouatchet, Achille, Mahieu, Rafael, Weiss, Emmanuel, Schnell, David, Zahar, Jean-Ralph, Artiguenave, Margaux, Sophie, Paktoris-Papine, Espinasse, Florence, Sayed, Faten El, Dinh, Aurélien, Charron, Cyril, Geri, Guillaume, Vieillard-Baron, Antoine, Repessé, Xavier, Kallel, Hatem, Mayence, Claire, Houcke, Stéphanie, Guegueniat, Pascal, Hommel, Didier, Dhifaoui, Kaouther, Hajjej, Zied, Fatnassi, Amira, Sellami, Walid, Labbene, Iheb, Ferjani, Mustapha, Dachraoui, Fahmi, Nakkaa, Sabrine, M’ghirbi, Abdelwaheb, Adhieb, Ali, Braiek, Dhouha Ben, Hraiech, Kmar, Ousji, Ali, Ouanes, Islem, Zaineb, Hammouda, Abdallah, Saousen Ben, Ouanes-Besbes, Lamia, Abroug, Fekri, Klein, Simon, Miquet, Mattéo, Thouret, Jean-Marc, Peigne, Vincent, Daban, Jean-Louis, Boutonnet, Mathieu, Lenoir, Bernard, Merhbene, Takoua, Derreumaux, Celine, Seguin, Thierry, Conil, Jean-Marie, Kelway, Charlotte, Blasco, Valery, Nafati, Cyril, Harti, Karim, Reydellet, Laurent, Albanese, Jacques, Aicha, Narjess Ben, Meddeb, Khaoula, Khedher, Ahmed, Ayachi, Jihene, Fraj, Nesrine, Sma, Nesrine, Chouchene, Imed, Boussarsar, Mohamed, Yedder, Soumaya Ben, Samoud, Walid, Radhouene, Bousselmi, Mariem, Bousselmi, Ammar, Asma, Cheikh, Asma Ben, Lakhal, Hend Ben, Khelfa, Messaouda, Hamdaoui, Yamina, Bouafia, Nabiha, Trampont, Timothée, Daix, Thomas, Legarçon, Vincent, Karam, Henri Hani, Pichon, Nicolas, Essafi, Fatma, Foudhaili, Nasreddine, Thabet, Hafedh, Blel, Youssef, Brahmi, Nozha, Ezzouine, Hanane, Kerrous, Mahmoud, Haoui, Saad El, Ahdil, Soufiane, Benslama, Abdellatif, Abidi, Khalid, Dendane, Tarek, Oussama, Ssouni, Belayachi, Jihane, Madani, Naoufal, Abouqal, Redouane, Zeggwagh, Amine Ali, Ghadhoune, Hatem, Chaari, Anis, Jihene, Guissouma, Allouche, Hend, Trabelsi, Insaf, Brahmi, Habib, Samet, Mohamed, Ghord, Hatem El, Habiba, Ben Sik Ali, Hajer, Nouira, Tilouch, Najla, Yaakoubi, Sondes, Jaoued, Oussama, Gharbi, Rim, Hassen, Mohamed Fekih, Elatrous, Souheil, Arcizet, Julien, Leroy, Bertrand, Abdulmalack, Caroline, Renzullo, Catherine, Hamet, Maël, Doise, Jean-Marc, Coutet, Jérôme, Cheikh, Chaigar Mohammed, Quechar, Zakaria, Joris, Magalie, Beauport, Dimitri Titeca, Kontar, Loay, Lebon, Delphine, Gruson, Bérengère, Slama, Michel, Marolleau, Jean-Pierre, Maizel, Julien, Gorham, Julie, Ameye, Lieveke, Berghmans, Thierry, Paesmans, Marianne, Sculier, Jean-Paul, Meert, Anne-Pascale, Guillot, Max, Ledoux, Marie-Pierre, Braun, Thierry, Maestraggi, Quentin, Michard, Baptiste, Castelain, Vincent, Herbrecht, Raoul, Schneider, Francis, Couffin, Severine, Lobo, David, Mongardon, Nicolas, Dhonneur, Gilles, Mounier, Roman, Le Borgne, Pierrick, Couraud, Sophie, Herbrecht, Jean-Etienne, Boivin, Alexandra, Lefebvre, François, Bilbault, Pascal, Zelmat, Setti-Aouicha, Batouche, Djamila-Djahida, Mazour, Fatima, Chaffi, Belkacem, Benatta, Nadia, Sik, Ali Habiba, Talik, I., Perrier, Maxime, Gouteix, Eliane, Koubi, Claude, Escavy, Annabelle, Guilbaut, Victoria, Fosse, Jean-Philippe, Jazia, Rahma Ben, Abdelghani, Ahmed, Cungi, Pierre-Julien, Bordes, Julien, Nguyen, Cédric, Pierrou, Candice, Cruc, Maximilien, Benois, Alain, Duprez, Frédéric, Bonus, Thierry, Cuvelier, Grégory, Ollieuz, Sandra, Machayekhi, Sharam, Paciorkowski, Frédéric, Reychler, Gregory, Coudroy, Remi, Thille, Arnaud W., Drouot, Xavier, Diaz, Véronique, Meurice, Jean-Claude, Robert, René, Turki, Olfa, Ben, Hmida Chokri, Assefi, Mona, Deransy, Romain, Brisson, Hélène, Monsel, Antoine, Conti, Filomena, Scatton, Olivier, Langeron, Olivier, Ghezala, Hassen Ben, Snouda, Salah, Ben, Chiekh Imen, Kaddour, Moez, Armel, Anwar, Youness, Lafrikh, Abdelhak, Bensaid, Youssef, Miloudi, Najib, Al Harrar, Mustapha, Amouzoun, Noufel, Mtioui, Mohamed, Zamd, Salma, El Khayat, Ghizlane, Medkouri, Mohamed, Benghanam, Benyounes, Ramdani, Montini, Florent, Moschietto, Sébastien, Gregoire, Emilien, Claisse, Guillaume, Guiot, Julien, Morimont, Philippe, Krzesinski, Jean-Marie, Mariat, Christophe, Lambermont, Bernard, Cavalier, Etienne, Delanaye, Pierre, Benbernou, Soumia, Ilies, Sofiane, Azza, Abdelkader, Bouyacoub, Khalida, Louail, Meriem, Mokhtari-Djebli, Houria, Arrestier, Romain, Daviaud, Fabrice, Francois, Xavier Laborne, Brocas, Elsa, Choukroun, Gérald, Peñuelas, Oscar, Lorente, José-Angel, Cardinal-Fernandez, Pablo, Rodriguez, José-Maria, Aramburu, José-Antonio, Esteban, Andres, Frutos-Vivar, Fernando, Bitker, Laurent, Costes, Nicolas, Le Bars, Didier, Lavenne, Franck, Devouassoux, Mojgan, Richard, Jean-Christophe, Mechati, Malika, Gainnier, Marc, Papazian, Laurent, Guervilly, Christophe, Garnero, Aude, Arnal, Jean Michel, Roze, Hadrien, Richard, Jean Christophe, Repusseau, Benjamin, Dewitte, Antoine, Joannes-Boyau, Olivier, Ouattara, Alexandre, Harbouze, Nadia, Amine, A. M., Olandzobo, A. G., Herbland, Alexandre, Richard, Marie, Girard, Nicolas, Lambron, Lucile, Lesieur, Olivier, Wainschtein, Sarah, Hubert, Sidonie, Hugues, Albane, Tran, Marc, Bouillard, Philippe, Loteanu, Vlad, Leloup, Maxime, Laurent, Alexandra, Lheureux, Florent, Prestifilippo, Alessia, Cruz, Martin Delgado Maria, Romain, Rigal, Antonelli, Massimo, Blanch, Torra Lluis, Bonnetain, Franck, Grazzia-Bocci, Maria, Mancebo, Jordi, Samain, Emmanuel, Paul, Hebert, Capellier, Gilles, Zavgorodniaia, Taissa, Soichot, Marion, Malissin, Isabelle, Voicu, Sebastian, Garçon, Pierre, Goury, Antoine, Kerdjana, Lamia, Deye, Nicolas, Bourgogne, Emmanuel, Megarbane, Bruno, Mejri, Olfa, Hmida, Marwa Ben, Tannous, Salma, Chevillard, Lucie, Labat, Laurence, Risede, Patricia, Fredj, Hana, Léger, Maxime, Brunet, Marion, Le Roux, Gaël, Boels, David, Lerolle, Nicolas, Farah, Souaad, Amiel-Niemann, Hélène, Kubis, Nathalie, Declèves, Xavier, Peyraux, Nicoals, Baud, Frederic, Serafini, Micaela, Alvarez, Jean-Claude, Heinzelman, Annette, Jozwiak, Mathieu, Millasseau, Sandrine, Teboul, Jean-Louis, Alphonsine, Jean-Emmanuel, Depret, François, Richard, Nathalie, Attal, Pierre, Richard, Christian, Monnet, Xavier, Chemla, Denis, Jerbi, Salma, Khedhiri, Wafa, Necib, Hatem, Scarfo, Paolo, Chevalier, Charles, Piagnerelli, Michael, Lafont, Alexandre, Galy, Antoine, Mancia, Claire, Zerhouni, Amel, Tabeliouna, Kheira, Gaja, Ali, Hamrouni, Bassem, Malouch, Abir, Fourati, Sami, Messaoud, Rihab, Zarrouki, Youssef, Ziadi, Amra, Rhezali, Manal, Zouizra, Zahira, Boumzebra, Drissi, Samkaoui, Mohamed Abdennasser, Brunet, Jennifer, Canoville, Bertrand, Verrier, Pierre, Ivascau, Calin, Seguin, Amélie, Valette, Xavier, Du Cheyron, Damien, Daubin, Cedric, Bougouin, Wulfran, Aissaoui, Nadia, Lamhaut, Lionel, Jost, Daniel, Maupain, Carole, Beganton, Frankie, Bouglé, Adrien, Dumas, Florence, Marijon, Eloi, Jouven, Xavier, Cariou, Alain, Poirson, Florent, Chaput, Ulriikka, Beeken, Thomas, Maxime, Leclerc, Haikel, Oueslati, Vodovar, Dominique, Chelly, Jonathan, Marteau, Philippe, Chocron, Richard, Juvin, Philippe, Loeb, Thomas, Adnet, Frederic, Lecarpentier, Eric, Riviere, Antoine, De Cagny, Bertand, Soupison, Thierry, Privat, Elodie, Escutnaire, Joséphine, Dumont, Cyrielle, Baert, Valentine, Vilhelm, Christian, Hubert, Hervé, Leteurtre, Stéphane, Fresco, Marion, Bubenheim, Michael, Beduneau, Gaetan, Carpentier, Dorothée, Grange, Steven, Artaud-Macari, Elise, Misset, Benoit, Tamion, Fabienne, Girault, Christophe, Dumas, Guillaume, Chevret, Sylvie, Lemiale, Virginie, Mokart, Djamel, Mayaux, Julien, Pène, Frédéric, Nyunga, Martine, Perez, Pierre, Moreau, Anne-Sophie, Bruneel, Fabrice, Vincent, François, Klouche, Kada, Reignier, Jean, Rabbat, Antoine, Azoulay, Elie, Frat, Jean-Pierre, Ragot, Stéphanie, Constantin, Jean-Michel, Prat, Gwenael, Mercat, Alain, Boulain, Thierry, Demoule, Alexandre, Devaquet, Jérôme, Nseir, Saad, Charpentier, Julien, Argaud, Laurent, Beuret, Pascal, Ricard, Jean-Damien, Teiten, Christelle, Marjanovic, Nicolas, Palamin, Nicola, L’Her, Erwan, Bailly, Arthur, Boisramé-Helms, Julie, Champigneulle, Benoit, Kamel, Toufik, Mercier, Emmanuelle, Le Thuaut, Aurélie, Lascarrou, Jean-Baptiste, Rolle, Amélie, De Jong, Audrey, Chanques, Gérald, Jaber, Samir, Hariri, Geoffroy, Baudel, Jean-Luc, Dubée, Vincent, Preda, Gabriel, Bourcier, Simon, Joffre, Jeremie, Bigé, Naïke, Ait-Oufella, Hafid, Maury, Eric, Mater, Houda, Merdji, Hamid, Grimaldi, David, Rousseau, Christophe, Mira, Jean-Paul, Chiche, Jean-Daniel, Sedghiani, Ines, Benabderrahim, A., Hamdi, Dhekra, Jendoubi, Asma, Cherif, Mohamed Ali, Hechmi, Youssef Zied El, Zouheir, Jerbi, Bagate, François, Bousselmi, Radhwen, Schortgen, Frédérique, Asfar, Pierre, Guérot, Emmanuel, Fabien, Grelon, Anguel, Nadia, Sigismond, Lasocki, Matthieu, Henry-Lagarrigue, Gonzalez, Frédéric, François, Legay, Guitton, Christophe, Schenck, Maleka, Jean-Marc, Doise, Dreyfuss, Didier, Radermacher, Peter, Frère, Antoine, Martin-Lefèvre, Laurent, Colin, Gwenhaël, Fiancette, Maud, Henry-Laguarrigue, Matthieu, Lacherade, Jean-Claude, Lebert, Christine, Vinatier, Isabelle, Yehia, Aihem, Joret, Aurélie, Menunier-Beillard, Nicolas, Benzekri-Lefevre, Dalila, Desachy, Arnaud, Bellec, Fréderic, Plantefève, Gaëtan, Quenot, Jean-Pierre, Meziani, Ferhat, Tavernier, Elsa, Ehrmann, Stephan, Chudeau, Nicolas, Raveau, Tommy, Moal, Valérie, Houillier, Pascal, Rouve, Emmanuelle, Lakhal, Karim, Gandonnière, Charlotte Salmon, Jouan, Youenn, Bodet-Contentin, Laetitia, Balmier, Adrien, Messika, Jonathan, De Montmollin, Etienne, Pouyet, Victorine, Sztrymf, Benjamin, Thiagarajah, Abirami, Roux, Damien, De Chambrun, Marc Pineton, Luyt, Charles-Edouard, Beloncle, François, Zapella, Nathalie, Ledochowsky, Stanislas, Terzi, Nicolas, Mazou, Jean-Marc, Sonneville, Romain, Paulus, Sylvie, Fedun, Yannick, Landais, Mickael, Raphalen, Jean-Herlé, Combes, Alain, Amoura, Zahir, Jacquemin, Aemilia, Guerrero, Felipe, Marcheix, Bertrand, Hernandez, Nicolas, Fourcade, Olivier, Georges, Bernard, Delmas, Clément, Makoudi, Sarah, Genton, Audrey, Bernard, Rémy, Lebreton, Guillaume, Amour, Julien, Mazet, Charlotte, Bounes, Fanny, Murat, Gurbuz, Cronier, Laure, Robin, Guillaume, Biendel, Caroline, Silva, Stein, Boubeche, Samia, Abriou, Caroline, Wurtz, Véronique, Scherrer, Vincent, Rey, Nathalie, Gastaldi, Gioia, Veber, Benoit, Doguet, Fabien, Gay, Arnaud, Dureuil, Bertrand, Besnier, Emmanuel, Rouget, Antoine, Gantois, Guillaume, Magalhaes, Eric, Wanono, Ruben, Smonig, Roland, Lermuzeaux, Mathilde, Lebut, Jordane, Olivier, Andremont, Dupuis, Claire, Radjou, Aguila, Mourvillier, Bruno, Neuville, Mathilde, D’ortho, Marie Pia, Bouadma, Lila, Rouvel-Tallec, Anny, Rudler, Marika, Weiss, Nicolas, Perlbarg, Vincent, Galanaud, Damien, Thabut, Dominique, Rachdi, Emna, Mhamdi, Ghada, Trifi, Ahlem, Abdelmalek, Rim, Abdellatif, Sami, Daly, Foued, Nasri, Rochdi, Tiouiri, Hanene, Lakhal, Salah Ben, Rousseau, Geoffroy, Asmolov, Romain, Grammatico-Guillon, Leslie, Auvet, Adrien, Laribi, Said, Garot, Denis, Dequin, Pierre François, Guillon, Antoine, Fergé, Jean-Louis, Abgrall, Gwénolé, Hinault, Ronan, Vally, Shazima, Roze, Benoit, Chaplain, Agathe, Chabartier, Cyrille, Savidan, Anne-Charlotte, Marie, Sabia, Cabie, Andre, Resiere, Dabor, Valentino, Ruddy, Mehdaoui, Hossein, Benarous, Lucas, Soda-Diop, Marième, Bouzana, Fouad, Perrin, Gilles, Bourenne, Jeremy, Eon, Béatrice, Lambert, Dominique, Trebuchon, Agnes, Poncelet, Géraldine, Le Bourgeois, Fleur, Michael, Levy, Camille, Guillot, Naudin, Jérôme, Deho, Anna, Dauger, Stéphane, Sauthier, Michaël, Bergeron-Gallant, Krystale, Emeriaud, Guillaume, Jouvet, Philippe, Tiebergien, Nicolas, Jacquet-Lagrèze, Matthias, Fellahi, Jean-Luc, Baudin, Florent, Essouri, Sandrine, Javouhey, Etienne, Guérin, Claude, Lampin, Marie, Mamouri, Ouardia, Devos, Patrick, Karaca-Altintas, Yasemin, Vinchon, Matthieu, Brossier, David, Eltaani, Redha, Teyssedre, Sonia, Sabine, Meyet, Bouchut, Jean-Christophe, Peguet, Olivier, Petitdemange, Lucie, Guilbert, Anne Sophie, Aoul, Nabil Tabet, Addou, Zakaria, Aouffen, Nabil, Anas, Benqqa, Kalouch, Samira, Yaqini, Khalid, Chlilek, Aziz, Abdou, Rchi, Gravellier, Perrine, Chantreuil, Julie, Travers, Nadine, Listrat, Antoine, Le Reun, Claire, Favrais, Geraldine, Coppere, Zoe, Blanot, Stéphane, Montmayeur, Juliette, Bronchard, Régis, Rolando, Stephane, Orliaguet, Gilles, Leger, Pierre-Louis, Rambaud, Jérôme, Thueux, Emilie, De Larrard, Alexandra, Berthelot, Véronique, Denot, Julien, Reymond, Marie, Amblard, Alain, Morin-Zorman, Sarah, Lengliné, Etienne, Pichereau, Claire, Mariotte, Eric, Emmanuel, Canet, Poujade, Julien, Trumpff, Guillaume, Janssen-Langenstein, Ralf, Harlay, Marie-Line, Zaid, Noorah, Ait-Ammar, Nawel, Bonnal, Christine, Merle, Jean-Claude, Botterel, Francoise, Levesque, Eric, Riad, Zakaria, Mezidi, Mehdi, Yonis, Hodane, Aublanc, Mylène, Perinel-Ragey, Sophie, Lissonde, Floriane, Louf-Durier, Aurore, Tapponnier, Romain, Louis, Bruno, Forel, Jean-Marie, Bisbal, Magali, Lehingue, Samuel, Rambaud, Romain, Adda, Mélanie, Hraiech, Sami, Marchi, Elisa, Roch, Antoine, Guerin, Vincent, Rozencwajg, Sacha, Schmidt, Matthieu, Hekimian, Guillaume, Bréchot, Nicolas, Trouillet, Jean Louis, Besset, Sébastien, Franchineau, Guillaume, Nieszkowska, Ania, Pascal, Leprince, Loiselle, Maud, Sarah, Chemam, Laurence, Dangers, Guillemette, Thomas, Jacquens, Alice, Kerever, Sebastien, Guidet, Bertrand, Aegerter, Philippe, Das, Vincent, Fartoukh, Muriel, Hayon, Jan, Desmard, Mathieu, Fulgencio, Jean-Pierre, Zuber, Benjamin, Soufi, A., Khaleq, K., Hamoudi, D., Garret, Charlotte, Peron, Matthieu, Coron, Emmanuel, Bretonnière, Cédric, Audureau, Etienne, Audrey, Winters, Christophe, Duvoux, Christian, Jacquelinet, Daniel, Azoulay, Cyrille, Feray, Aissaoui, Wissal, Rghioui, Kawtar, Haddad, Wafae, Barrou, Houcine, Carteaux-Taeib, Anna, Lupinacci, Renato, Manceau, Gilles, Jeune, Florence, Tresallet, Christophe, Habacha, Sahar, Fathallah, Ines, Zoubli, Aymen, Aloui, Rafaa, Kouraichi, Nadia, Jouet, Emilie, Badin, Julie, Fermier, Brice, Feller, Marc, Serie, Mathieu, Pillot, Jérôme, Marie, William, Gisbert-Mora, Chloé, Vinclair, Camille, Lesbordes, Pierre, Mathieu, Pascal, De Brabant, Fabienne, Muller, Emmanuel, Robaux, Marie-Aline, Giabicani, Mikhael, Marchalot, Antoine, Gelinotte, Stéphanie, Declercq, Pierre Louis, Eraldi, Jean-Pierre, Bougerol, François, Meunier-Beillard, Nicolas, Devilliers, Hervé, Rigaud, Jean-Philippe, Verrière, Camille, Ardisson, Fanny, Kentish-Barnes, Nancy, Jacq, Gwenaëlle, Chermak, Akli, Lautrette, Alexandre, Legrand, Matthieu, Soummer, Alexis, Thiery, Guillaume, Cottereau, Alice, Canet, Emmanuel, Caujolle, Marie, Allyn, Jérôme, Valance, Dorothée, Brulliard, Caroline, Martinet, Olivier, Jabot, Julien, Gallas, Thomas, Vandroux, David, Allou, Nicolas, Durand, Arthur, Nevière, Rémi, Delguste, Florian, Boulanger, Eric, Preau, Sebastien, Martin, Ruste, Cochet, Hélène, Ponthus, Jean Pierre, Amilien, Virginie, Tchir, Martial, Barsam, Elise, Ayoub, Mohsen, Georger, Jean Francois, Guillame, Izaute, Assaraf, Julie, Tripon, Simona, Mallet, Maxime, Barbara, Guilaume, Louis, Guillaume, Gaudry, Stéphane, Barbarot, Nicolas, Jamet, Angéline, Outin, Hervé, Gibot, Sébastien, Bollaert, Pierre-Edouard, Holleville, Mathilde, Legriel, Stéphane, Chateauneuf, Anne Laure, Cavelot, Sébastien, Moyer, Jean-Denis, Bedos, Jean Pierre, Merle, Philippe, Laine, Aurelie, Natalie, De Sa, Cornuault, Mathieu, Libot, Jérome, Asehnoune, Karim, Rozec, Bertrand, Dantal, Jacques, Videcoq, Michel, Degroote, Thècle, Jaillette, Emmanuelle, Zerimech, Farid, Malika, Balduyck, Llitjos, Jean-François, Amara, Marlène, Lacave, Guillaume, Pangon, Béatrice, Mavinga, José, Makunza, Joseph Nsiala, Mafuta, M. E., Yanga, Yves, Eric, Amisi, Ilunga, Jp, Kilembe, Ma, Alby-Laurent, Fanny, Toubiana, Julie, Mokline, Amel, Laajili, Achraf, Amri, Helmi, Rahmani, Imene, Mensi, Nidhal, Gharsallah, Lazheri, Tlaili, Sofiene, Gasri, Bahija, Hammouda, Rym, Messadi, Amen Allah, Allain, Pierre-Antoine, Gault, Nathallie, Paugam-Burtz, Catherine, Foucrier, Arnaud, Chatbri, Bassem, Bourbiaa, Yousra, Thabet, Lamia, Neuschwander, Arthur, Vincent, Looten, Beck, Jennifer, Vibol, Chhor, Amelie, Yavchitz, Resche-Rigon, Matthieu, Pirracchio, Jean MantzRomain, Bureau, Côme, Decavèle, Maxens, Campion, Sébastien, Ainsouya, Roukia, Niérat, Marie-Cécile, Prodanovic, Hélène, Raux, Mathieu, Similowski, Thomas, Dubé, Bruno-Pierre, Demiri, Suela, Dres, Martin, May, Faten, Quintard, Hervé, Kounis, Ilias, Saliba, Faouzi, André, Stephane, Boudon, Marc, Ichai, Philippe, Younes, Aline, Nakad, Lionel, Coilly, Audrey, Antonini, Teresa, Sobesky, Rodolphe, De Martin, Eleonora, Samuel, Didier, Hubert, Noemie, Nay, Mai-Anh, Auchabie, Johann, Giraudeau, Bruno, Jean, Reignier, Darmon, Michaël, Ruckly, Stephane, Garrouste-Orgeas, Maïté, Gratia, Elisabeth, Goldgran-Toledano, Dany, Jamali, Samir, Dumenil, Anne Sylvie, Schwebel, Carole, Brisard, Laurent, Bizouarn, Philippe, Lepoivre, Thierry, Nicolet, Johanna, Rigal, Jean Christophe, Roussel, Jean Christian, Cheurfa, Cherifa, Abily, Julien, Lescot, Thomas, Page, Isaline, Warnier, Stéphanie, Nys, Monique, Rousseau, Anne-Françoise, Damas, Pierre, Uhel, Fabrice, Lesouhaitier, Mathieu, Grégoire, Murielle, Gaudriot, Baptiste, Gacouin, Arnaud, Le Tulzo, Yves, Flecher, Erwan, Tarte, Karin, Tadié, Jean-Marc, Georges, Quentin, Soares, M., Jeon, Kyeongman, Oeyen, Sandra, Rhee, Chin Kook, Gruber, Pascale, Ostermann, Marlies, Hill, Quentin, Depuydt, Peter, Ferra, Christelle, Muller, Alice, Aurelie, Bourmaud, Niles, Christopher, Herbert, Fabien, Pied, Sylviane, Loridant, Séverine, François, Nadine, Bignon, Anne, Sendid, Boualem, Lemaitre, Caroline, Dupre, Celine, Zayene, Aymen, Portier, Lucie, De Freitas Caires, Nathalie, Lassalle, Philippe, Le Neindre, Aymeric, Selot, Pascal, Ferreiro, Daniel, Bonarek, Maria, Henriot, Stépahen, Rodriguez, Julie, Taddei, Mara, Di Bari, Mauro, Hickmann, Cheryl, Castanares-Zapatero, Diego, Deldicque, Louise, Van Den Bergh, Peter, Caty, Gilles, Roeseler, Jean, Francaux, Marc, Laterre, Pierre-François, Dupuis, Bastien, Machayeckhi, Sharam, Sarfati, Celine, Moore, Alex, Mendialdua, Paula, Rodet, Emilie, Pilorge, Catherine, Stephan, Francois, Rezaiguia-Delclaux, Saida, Dugernier, Jonathan, Hesse, Michel, Jumetz, Thibaud, Bialais, Emilie, Depoortere, Virginie, Michotte, Jean Bernard, Wittebole, Xavier, Jamar, François, REA‑RAISIN Studygroup, OUTCOMEREA study group, Sudden Death Expertise Center, for the HYPER2S Investigators and REVA research network, Clinical Research in Intensive Care and Sepsis (CRICS network), Cubrea network, and Brain Liver Pitié-Salpêtrière Study Group (BLIPS)

Published
2017
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9. Correction: Human IgA bind a diverse array of commensal bacteria

Author

Sterlin, Delphine, primary, Fadlallah, Jehane, additional, Adams, Olivia, additional, Fieschi, Claire, additional, Parizot, Christophe, additional, Dorgham, Karim, additional, Rajkumar, Asok, additional, Autaa, Gaëlle, additional, El-Kafsi, Hela, additional, Charuel, Jean-Luc, additional, Juste, Catherine, additional, Jönsson, Friederike, additional, Candela, Thomas, additional, Wardemann, Hedda, additional, Aubry, Alexandra, additional, Capito, Carmen, additional, Brisson, Hélène, additional, Tresallet, Christophe, additional, Cummings, Richard D., additional, Larsen, Martin, additional, Yssel, Hans, additional, von Gunten, Stephan, additional, and Gorochov, Guy, additional

Published
2020
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10. Human IgA binds a diverse array of commensal bacteria

Author

Sterlin, Delphine, primary, Fadlallah, Jehane, additional, Adams, Olivia, additional, Fieschi, Claire, additional, Parizot, Christophe, additional, Dorgham, Karim, additional, Rajkumar, Asok, additional, Autaa, Gaëlle, additional, El-Kafsi, Hela, additional, Charuel, Jean-Luc, additional, Juste, Catherine, additional, Jönsson, Friederike, additional, Candela, Thomas, additional, Wardemann, Hedda, additional, Aubry, Alexandra, additional, Capito, Carmen, additional, Brisson, Hélène, additional, Tresallet, Christophe, additional, Cummings, Richard D., additional, Larsen, Martin, additional, Yssel, Hans, additional, von Gunten, Stephan, additional, and Gorochov, Guy, additional

Published
2019
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14. Multidrug-resistant bacteria transmitted through high-density EEG in ICU

Author

Weiss, Nicolas, Faugeras, Frédéric, Rohaut, Benjamin, Leconte, Jocelyne, Lafeuille, Emilie, Brossier, Florence, Bourmaleau, Julie, Lefebvre, Sandrine, Lafaye, Catherine, Quirins, Marion, Valente, Mélanie, Brisson, Hélène, Mayaux, Julien, Rudler, Marika, Bréchot, Nicolas, Demeret, Sophie, Bolgert, Francis, Robert, Jérome, and Naccache, Lionel

Published
2016
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15. Training for Lung Ultrasound Score Measurement in Critically Ill Patients

Author

Rouby, Jean-Jacques, primary, Arbelot, Charlotte, additional, Gao, Yuzhi, additional, Zhang, Mao, additional, Lv, Jie, additional, An, Youzhong, additional, Chunyao, Wang, additional, Bin, Du, additional, Valente Barbas, Carmen Silvia, additional, Dexheimer Neto, Felippe Leopoldo, additional, Prior Caltabeloti, Fabiola, additional, Lima, Emidio, additional, Cebey, Andres, additional, Perbet, Sébastien, additional, Constantin, Jean-Michel, additional, Rouby, Jean-Jacques, additional, Brisson, Hélène, additional, Deransy, Romain, additional, Vezinet, Corinne, additional, Garçon, Pierre, additional, El Hadj Kacem, Nabil, additional, Lemesle, Denis, additional, Monsel, Antoine, additional, Lu, Qin, additional, Langeron, Olivier, additional, Gay, Frédérick, additional, Lucena, Bruno, additional, Malbouisson, Luiz, additional, Carvalho Carmona, Maria José, additional, Neves, Julio, additional, de Tarso Roth Dalcin, Paulo, additional, de Paula Pinto Schettino, Guilherme, additional, Biestro, Alberto, additional, Cristovao, Davi, additional, and Salluh, Jorge, additional

Published
2018
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16. Unexpected good outcome in severe cerebral fat embolism syndrome

Author

Hermann, Bertrand, primary, Brisson, Hélène, additional, Langeron, Olivier, additional, Pyatigorskaya, Nadya, additional, Paquereau, Julie, additional, Robert, Hélène, additional, Stender, Johan, additional, Habert, Marie‐Odile, additional, Naccache, Lionel, additional, and Monsel, Antoine, additional

Published
2018
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17. In Reply

Author

Monsel, Antoine, primary, Le Corre, Marine, additional, Brisson, Hélène, additional, Arbelot, Charlotte, additional, Vezinet, Corinne, additional, Fléron, Marie-Hélène, additional, Lu, Qin, additional, Langeron, Olivier, additional, and Rouby, Jean-Jacques, additional

Published
2016
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19. Diagnostic accuracy of the bedside lung ultrasound in emergency protocol for the diagnosis of acute respiratory failure in spontaneously breathing patients

Author

Dexheimer Neto, Felippe Leopoldo, Andrade, Juliana Mara Stormovski de, Raupp, Ana Carolina Tabajara, Townsend, Raquel da Silva, Beltrami, Fabiana Gabe, Brisson, Hélène, Lu, Qin, and Dalcin, Paulo de Tarso Roth

Subjects
Intensive care units, Insuficiência respiratória aguda, Ultrasonography, interventional, Respiratory insufficiency, Ventilação pulmonar
Abstract

Objetivo: O ultrassom pulmonar (USP) à beira do leito é uma técnica de imagem não invasiva e prontamente disponível que pode complementar a avaliação clínica. O protocolo Bedside Lung Ultrasound in Emergency (BLUE, ultrassom pulmonar à beira do leito em situações de emergência) demonstrou elevado rendimento diagnóstico em pacientes com insuficiência respiratória aguda (IRpA). Recentemente, um programa de treinamento em USP à beira do leito foi implementado na nossa UTI. O objetivo deste estudo foi avaliar a acurácia do USP baseado no protocolo BLUE, quando realizado por médicos com habilidades básicas em ultrassonografia, para orientar o diagnóstico de IRpA. Métodos: Ao longo de um ano, todos os pacientes adultos consecutivos respirando espontaneamente admitidos na UTI por IRpA foram prospectivamente inclusos. Após treinamento, 4 operadores com habilidades básicas em ultrassonografia realizaram o USP em até 20 minutos após a admissão na UTI, cegados para a história do paciente. Os diagnósticos do USP foram comparados aos diagnósticos da equipe assistente ao final da internação na UTI (padrão-ouro). Resultados: Foram inclusos na análise 37 pacientes (média etária: 73,2 ± 14,7 anos; APACHE II: 19,2 ± 7,3). O diagnóstico do USP demonstrou concordância com o diagnóstico final em 84% dos casos (kappa total: 0,81). As causas mais comuns de IRpA foram pneumonia (n = 17) e edema pulmonar cardiogênico (n = 15). A sensibilidade e a especificidade do USP comparado ao diagnóstico final foram de 88% e 90% para pneumonia e de 86% e 87% para edema pulmonar cardiogênico, respectivamente. Conclusões: O USP baseado no protocolo BLUE foi reproduzível por médicos com habilidades básicas em ultrassonografia e acurado para o diagnóstico de pneumonia e de edema pulmonar cardiogênico. Objective: Bedside lung ultrasound (LUS) is a noninvasive, readily available imaging modality that can complement clinical evaluation. The Bedside Lung Ultrasound in Emergency (BLUE) protocol has demonstrated a high diagnostic accuracy in patients with acute respiratory failure (ARF). Recently, bedside LUS has been added to the medical training program of our ICU. The aim of this study was to investigate the accuracy of LUS based on the BLUE protocol, when performed by physicians who are not ultrasound experts, to guide the diagnosis of ARF. Methods: Over a one-year period, all spontaneously breathing adult patients consecutively admitted to the ICU for ARF were prospectively included. After training, 4 non-ultrasound experts performed LUS within 20 minutes of patient admission. They were blinded to patient medical history. LUS diagnosis was compared with the final clinical diagnosis made by the ICU team before patients were discharged from the ICU (gold standard). Results: Thirty-seven patients were included in the analysis (mean age, 73.2 ± 14.7 years; APACHE II, 19.2 ± 7.3). LUS diagnosis had a good agreement with the final diagnosis in 84% of patients (overall kappa, 0.81). The most common etiologies for ARF were pneumonia (n = 17) and hemodynamic lung edema (n = 15). The sensitivity and specificity of LUS as measured against the final diagnosis were, respectively, 88% and 90% for pneumonia and 86% and 87% for hemodynamic lung edema. Conclusions: LUS based on the BLUE protocol was reproducible by physicians who are not ultrasound experts and accurate for the diagnosis of pneumonia and hemodynamic lung edema.

Published
2015

20. Tapered-cuff Endotracheal Tube Does Not Prevent Early Postoperative Pneumonia Compared with Spherical-cuff Endotracheal Tube after Major Vascular Surgery

Author

Monsel, Antoine, primary, Lu, Qin, additional, Le Corre, Marine, additional, Brisson, Hélène, additional, Arbelot, Charlotte, additional, Vezinet, Corinne, additional, Fléron, Marie-Hélène, additional, Ibanez-Estève, Christina, additional, Zerimech, Farid, additional, Balduyck, Malika, additional, Dexheimer, Felippe, additional, Wang, Chunyao, additional, Langeron, Olivier, additional, and Rouby, Jean-Jacques, additional

Published
2016
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21. Treating hepatic encephalopathy in cirrhotic patients admitted to ICU with sodium phenylbutyrate: a preliminary study.

Author

Weiss, Nicolas, Tripon, Simona, Lodey, Marion, Guiller, Elsa, Junot, Helga, Monneret, Denis, Mayaux, Julien, Brisson, Hélène, Mallet, Maxime, Rudler, Marika, Imbert‐Bismut, Françoise, Thabut, Dominique, and the Brain‐Liver Pitié‐Salpêtrière Study Group (BLIPS)

Subjects
CIRRHOSIS of the liver, TREATMENT of cirrhosis of the liver, HEPATIC encephalopathy, DRUG efficacy, DRUG prescribing, PATIENTS, THERAPEUTICS
Abstract

Abstract: Hepatic encephalopathy (HE) influences short‐term and long‐term prognoses. Recently, glycerol phenylbutyrate (PB), that lowers ammonia by providing an alternate pathway to urea for waste nitrogen excretion, has shown that it was effective in preventing the occurrence of HE in RCT. The aim was to assess the benefits of sodium PB in cirrhotic patients admitted to ICU for overt HE, in terms of ammonia levels decrease, neurological improvement, and survival. Cirrhotic patients who presented with overt HE, ammonia levels >100 μmol/L, and did not display any contra‐indication were included. Sodium PB was administered at 200 mg/kg/day. Control group included historical controls treated by standard therapy, matched for age, sex, MELD score, and severity of HE. Eighteen patients were included and treated with sodium PB (age: 59 [45–68], male gender: 15 [83%], Child–Pugh B: 8 [44%], Child–Pugh C: 10 [56%], and MELD score: 16 [13–23]). Ammonia levels significantly decreased in the PB as compared to the control group from inclusion to 12 h and from inclusion to 48 h (P = 0.0201 and P = 0.0230, respectively). The proportion of patients displaying neurological improvement was only higher in the PB‐treated group as compared to controls at ICU discharge (15 [83%] vs. 9 [50%], P = 0.0339). ICU discharge survival was significantly higher in patients treated with PB (17 [94%] vs. 9 [50%], P = 0.0017). In cirrhotic patients with overt HE, sodium PB could be effective in reducing ammonia levels and might be effective in improving neurological status and ICU discharge survival. More extensive data, especially a RCT, are mandatory. [ABSTRACT FROM AUTHOR]

Published
2018
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22. Évaluation des performances des sondes d’intubation endotrachéales à ballonnet conique dans la prévention des pneumonies postopératoires de chirurgie majeure aortique : étude randomisée contrôlée

Author

Monsel, Antoine, primary, Lu, Qin, additional, Le Corre, Marine, additional, Brisson, Hélène, additional, Arbelot, Charlotte, additional, Pons, Antoine, additional, Vézinet, Corinne, additional, Zerimech, Farid, additional, Langeron, Olivier, additional, and Rouby, Jean-Jacques, additional

Published
2015
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23. Évaluation de l’imputabilité du staphylocoque à coagulase négative dans les pneumonies acquises sous ventilation mécanique : étude de cohorte, prospective, monocentrique

Author

Monsel, Antoine J., primary, Lu, Qin, additional, Delattre, Raphaëlle, additional, Zhou, Guang-Ju, additional, Renvoisé, Aurélie, additional, Pons, Antoine, additional, Brisson, Hélène, additional, Vandenesch, François, additional, Langeron, Olivier, additional, and Rouby, Jean-Jacques, additional

Published
2015
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25. Diagnostic accuracy of the Bedside Lung Ultrasound in Emergency protocol for the diagnosis of acute respiratory failure in spontaneously breathing patients,

Author

Dexheimer Neto, Felippe Leopoldo, primary, Andrade, Juliana Mara Stormovski de, additional, Raupp, Ana Carolina Tabajara, additional, Townsend, Raquel da Silva, additional, Beltrami, Fabiana Gabe, additional, Brisson, Hélène, additional, Lu, Qin, additional, and Dalcin, Paulo de Tarso Roth, additional

Published
2015
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26. Endotoxin-induced myocardial dysfunction in senescent rats

Author

Rozenberg, Sandrine, Besse, Sophie, Brisson, Hélène, Jozefowicz, Elsa, Kandoussi, Abdelmejid, Mebazaa, Alexandre, Riou, Bruno, Vallet, Benoît, Tavernier, Benoît, Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 (TCDV), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Droit et Santé-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Université Paris Descartes - Paris 5 (UPD5), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP), Université Denis Diderot – Paris 7, Laboratoire d'Anesthésiologie, Université Pierre et Marie Curie - Paris 6 (UPMC), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Laboratoire de Pharmacologie - EA 1046, Université de Lille, Pharmacologie de la mort neuronale et de la plasticité cérébrale, IFR114-Université de Lille, Droit et Santé, Fédération d'anesthésie réanimation, Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Laboratoire de recherche sur la croissance cellulaire, la réparation et la régénération tissulaires (LRCCRRT), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS), Récepteurs nucléaires, lipoprotéines et athérosclérose, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Droit et Santé, Laboratoire d'anesthésiologie, Université Paris Diderot - Paris 7 (UPD7)-EA322, Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), and Autard, Delphine

Subjects
Lipopolysaccharides, Male, Aging, [SDV]Life Sciences [q-bio], Research, Nitric Oxide, Myocardial Contraction, Thiobarbituric Acid Reactive Substances, [SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Rats, Oxidative Stress, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Escherichia coli, Animals, Lipid Peroxidation, Rats, Wistar, Cardiomyopathies
Abstract

International audience; Introduction: Aging is associated with a decline in cardiac contractility and altered immune function. The aim of this study was to determine whether aging alters endotoxin-induced myocardial dysfunction.Methods: Senescent (24 month) and young adult (3 month) male Wistar rats were treated with intravenous lipopolysaccharide (LPS) (0.5 mg/kg (senescent and young rats) or 5 mg/kg (young rats only)), or saline (senescent and young control groups). Twelve hours after injection, cardiac contractility (isolated perfused hearts), myofilament Ca2+ sensitivity (skinned fibers), left ventricular nitric oxide end-oxidation products (NOx and NO2) and markers of oxidative stress (thiobarbituric acid reactive species (TBARS) and antioxidant enzymes) were investigated.Results: LPS (0.5 mg/kg) administration resulted in decreased contractility in senescent rats (left ventricular developed pressure (LVDP), 25 +/- 4 vs 53 +/- 4 mmHg/g heart weight in control; P < 0.05) of amplitude similar to that in young rats with LPS 5 mg/kg (LVDP, 48 +/- 7 vs 100 +/- 7 mmHg/g heart weight in control; P < 0.05). In contrast to young LPS rats (0.5 and 5 mg/kg LPS), myofilament Ca2+ sensitivity was unaltered in senescent LPS hearts. Myocardial NOx and NO2 were increased in a similar fashion by LPS in young (both LPS doses) and senescent rats. TBARS and antioxidant enzyme activities were unaltered by sepsis whatever the age of animals.Conclusion: Low dose of LPS induced a severe myocardial dysfunction in senescent rats. Ca2+ myofilament responsiveness, which is typically reduced in myocardium of young adult septic rats, however, was unaltered in senescent rats. If these results are confirmed in in vivo conditions, they may provide a cellular explanation for the divergent reports on ventricular diastolic function in septic shock. In addition, Ca2+-sensitizing agents may not be as effective in aged subjects as in younger subjects.

Published
2006

28. Early fluid loading in acute respiratory distress syndrome with septic shock deteriorates lung aeration without impairing arterial oxygenation: a lung ultrasound observational study

Author

Caltabeloti, Fabiola Prior, primary, Monsel, Antoine, additional, Arbelot, Charlotte, additional, Brisson, Hélène, additional, Lu, Qin, additional, Gu, Wen-Jie, additional, Zhou, Guang-Ju, additional, C Auler, José O, additional, and Rouby, Jean-Jacques, additional

Published
2014
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29. Imipenem, Meropenem, or Doripenem To Treat Patients with Pseudomonas aeruginosa Ventilator-Associated Pneumonia

Author

Luyt, Charles-Edouard, primary, Aubry, Alexandra, additional, Lu, Qin, additional, Micaelo, Maïté, additional, Bréchot, Nicolas, additional, Brossier, Florence, additional, Brisson, Hélène, additional, Rouby, Jean-Jacques, additional, Trouillet, Jean-Louis, additional, Combes, Alain, additional, Jarlier, Vincent, additional, and Chastre, Jean, additional

Published
2014
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31. 105 Effects of a specifically-designed intensive care information system length of stay and mortality

Author

Movschin Marie, Brisson Hélène, Rouby Jean-Jacques, Lu Qin, Vezinet Corinne, Bouhemad Belaid, Bodin Liliane, and Arbelot Charlotte

Subjects
Gynecology, medicine.medical_specialty, Pediatrics, Sequential organ failure assessment, Critically ill, Tel aviv, business.industry, Health Policy, Acute respiratory disease, Patient care, Order entry, SAPS II, Intensive care, medicine, business
Abstract

Introduction An intensive care information system (ICIS) has numerous advantages. It enables all the patients9 data to be collected in a “computer file”. The automatic acquisition of data reduces human error, and computerised physician order entry limit errors in administering medication. Thanks to computerised data, the creation of a “clinical decision support system” enables diagnosis optimisation and follow-up of treatments. The goal of this study was to evaluate the impact of a personalised ICIS on critically ill patients9 mortality and length of stay in the intensive care unit (ICU). Materials and methods The system chosen for Multidisciplinary ICU (12 beds) of Pitie-Salpetriere hospital in Paris was the program Metavision (IMDsoft, Tel Aviv, Israel). It is an adjustable system, offering the possibility of being completely reformatted and adapted according to specific needs. A team consisting of doctors, nurses, auxiliary nurses, and monitors was trained for 2 weeks to use the program. Then, for 1 month, the ICIS was personalised for the unit before being implemented. After defining the various clinical, biological, and radiological parameters indispensable for diagnosis and follow-up of acute respiratory disease, haemodynamic, renal, and hepatic failures, screens were created, integrating pertinent parameters in the form of tables and graphics. These screens enable all the relevant elements to be grouped together, but also allow the visualisation of their evolution along time. We compared the Simplified Acute Physiology Score (SAPS II) and the Sequential Organ Failure Assessment (SOFA) at patient9s admission, length of patients9 stay in the ICU, and mortality over two 6-month periods: before the implementation of Metavision from June to November 2008, and after implementation, from March to August 2009. Data were compared between groups by a Mann–Whitney test (median and IQR 25–75%), and a χ 2 test. The first 3 months following the implementation of Metavision were not taken into account, in order to exclude the difficulties inherent to the implementation of a new computerised system. Results One hundred twelve patients were hospitalised between June and November 2008, and 160 between March and November 2009. SAPS II and SOFA scores showed no difference between the two groups: (SAPS II: 39 (26–54) vs 44 (28–59), p=0.7, SOFA: 6 (3–10) vs 6 (4–10), p=0.49). The length of stay in intensive care was shortened by 2 days after implementation of Metavision: 9 (5–20) versus 7 (3.5–14), p=0.02. A trend was observer towards a decrease in mortality: 17% to 14.5%, p=0.6. Discussion The interest of the system we have chosen is its adjustability, its ability to combine on the same screen (“clinical decision support screen”), a high number of clinical, biological, or radiological data. These screens enable the assessment of therapies on patients9 organ failures. ICIS enables optimisation of patient9s care, which may explain the reduction in duration of patients9 stay in the ICU. It overcomes the usual limits of ICIS consist of an imperfect adaptation to specific medical needs. Conclusion A specifically-designed intensive care information system enables improvement of patient care, and reduction of the length of stay in the ICU. It requires a substantial investment from physician regarding learning programs and creating personalised tools for diagnosis and follow up assistance. It also requires a close collaboration between physicians and computer scientists. Introduction L9informatisation d9un service de reanimation a de nombreux avantages. Elle permet de rassembler dans le « dossier informatique », toutes les donnees des patients. L9acquisition automatique des donnees diminue l9erreur humaine, et les logiciels de prescriptions limitent les erreurs d9administration de medicament. Grâce aux donnees informatisees, la creation d9un « Systeme d9aide aux decisions medicales » permet d9optimiser le diagnostic et le suivi des therapeutiques. Le but de cette etude etait d9evaluer l9impact de l9informatisation personnalisee du service sur la mortalite et la duree de sejour en reanimation. Materiel et methode Le systeme choisit pour informatiser le service de Reanimation Polyvalente (12 lits) est le logiciel Metavision (IMDsoft, Tel Aviv, Israel). Ce systeme est modulable. Il est livre avec la possibilite d9etre completement remis en forme et adapte en fonction des besoins du service. Une equipe composee de medecins, infirmiers, aides-soigants et surveillants a ete formee au logiciel pendant deux semaines. Puis pendant un mois le dossier a ete personnalise pour le service avant d9etre implante. L9accent a ete mis sur la creation d9 « ecrans d9aide au diagnostic ». Apres avoir defini les differents parametres cliniques, biologiques et radiologiques indispensables au diagnostic et a la prise en charge d9une pneumopathie, d9une defaillance hemodynamique, renale et hepatique, des ecrans ont ete crees en integrant ces parametres sous formes de tableau et de graphique. Ces ecrans permettent de regrouper tous les elements pertinents mais aussi de visualiser leur evolution dans le temps. Nous avons compare les scores d9Indice de Gravite Simplifie (IGS) et de defaillance d9organe (SOFA) a l9admission, la duree de sejour et la mortalite sur deux periodes de six mois: avant l9implantation du logiciel de juin a novembre 2008 et apres l9implantation de Mars a Aout 2009. Les deux groupes de patients ont ete analyses par un test de Mann-Whitney (mediane et 25–75% Interquartile) et un test de Chi-2. Les trois premiers mois suivant la mise en place du systeme n9ont pas ete pris en compte pour exclure les difficultes inherentes a la mise en place d9un nouveau systeme. Resultats Cent douze patients ont ete hospitalises entre juin et novembre 2008 et 160 entre mars et novembre 2009. Les scores d9IGS et de SOFA n9etaient pas differents entre les 2 groupes: [IGS: 39 (26–54) vs 44 (28–59), p=0.7; SOFA: 6 (3–10) vs 6 (4–10), p=0.49]. La duree d9hospitalisation en reanimation a ete raccourcie de 2 jours apres l9implantation du logiciel: 9 (5–20) vs 7 (3.5–14), p=0.02. La mortalite est passee de 17% a 14.5%, p=0.6. Discussion L9interet du systeme que nous avons choisi est sa plasticite, sa capacite a regrouper sur un meme ecran d9aide au diagnostic un nombre d9informations tres variables qu9elles soient cliniques, biologiques ou radiologiques. Ces ecrans permettent precisement d9evaluer et de suivre l9evolution des defaillances d9organes des patients. L9informatisation permet d9optimiser la prise en charge du patient ce qui pourrait expliquer la diminution de duree sejour en reanimation. Les limites des systemes informatiques sont qu9ils ne sont pas crees par les medecins et donc parfois imparfaitement adaptes aux besoins medicaux. Conclusion L9informatisation personnalisee d9un service permet d9ameliorer la prise en charge des patients et de raccourcir la duree de sejour en reanimation. Elle necessite un investissement important de la part des medecins en terme d9apprentissage du logiciel et de la creation d9outils personnalises d9aide au diagnostic. Elle requiert aussi une collaboration etroite entre medecins et informaticiens du systeme adopte et de l9hopital.

Published
2010

33. Extracorporeal membrane oxygenation as a bridge to liver transplantation for acute respiratory distress syndrome-induced life-threatening hypoxaemia aggravated by hepatopulmonary syndrome

Author

Monsel, Antoine, primary, Mal, Hervé, additional, Brisson, Hélène, additional, Luo, Rubin, additional, Eyraud, Daniel, additional, Vézinet, Corinne, additional, Do, Chung, additional, Lu, Qin, additional, Vaillant, Jean-Christophe, additional, Hannoun, Laurent, additional, Houssel, Pauline, additional, Durand, François, additional, and Rouby, Jean-Jacques, additional

Published
2011
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37. Acurácia diagnóstica do protocolo de ultrassom pulmonar à beira do leito em situações de emergência para diagnóstico de insuficiência respiratória aguda em pacientes com ventilação espontânea.

Author

Dexheimer Neto, Felippe Leopoldo, Stormovski de Andrade, Juliana Mara, Tabajara Raupp, Ana Carolina, da Silva Townsend, Raquel, Gabe Beltrami, Fabiana, Brisson, Hélène, Qin Lu, and de Tarso Roth Dalcin, Paulo

Subjects
ADULT respiratory distress syndrome, DIAGNOSTIC ultrasonic imaging, POINT-of-care testing, INTENSIVE care patients, ACCURACY, DIAGNOSTIC ultrasonic imaging instruments, STANDARDS, DIAGNOSIS
Abstract

Copyright of Brazilian Journal of Pulmonology / Jornal Brasileiro de Pneumologia is the property of Sociedade Brasileira de Pneumologia e Tisiologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2015
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39. Measurement of Alveolar Recruitment at the Bedside: The Beginning of a New Era in Respiratory Monitoring?

Author

Rouby, Jean-Jacques, Arbelot, Charlotte, Brisson, Hélène, Qin Lu, and Bouhemad, Belaïd

Subjects
PATIENT monitoring, PRESSURE breathing, ADULT respiratory distress syndrome, ULTRASONIC imaging
Abstract

The article discusses the measurement of positive end-expiratory pressure (PEEP)-induced alveolar-recruitment in inferring from regional changes in patients with acute respiratory distress syndrome (ARDS). It explores the use of pressure-volume (PV) curve method which requires long time before it can be used at the bedside of patients. The article also explores the use of PV recruitment module with eXtend ventilator and a study on the impact of gas exchange on the method.

Published
2013
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40. Imipenem, Meropenem, or Doripenem To Treat Patients with Pseudomonas aeruginosaVentilator-Associated Pneumonia

Author

Luyt, Charles-Edouard, Aubry, Alexandra, Lu, Qin, Micaelo, Maïté, Bréchot, Nicolas, Brossier, Florence, Brisson, Hélène, Rouby, Jean-Jacques, Trouillet, Jean-Louis, Combes, Alain, Jarlier, Vincent, and Chastre, Jean

Abstract

ABSTRACTOnly limited data exist on Pseudomonas aeruginosaventilator-associated pneumonia (VAP) treated with imipenem, meropenem, or doripenem. Therefore, we conducted a prospective observational study in 169 patients who developed Pseudomonas aeruginosaVAP. Imipenem, meropenem, and doripenem MICs for Pseudomonas aeruginosaisolates were determined using Etests and compared according to the carbapenem received. Among the 169 isolates responsible for the first VAP episode, doripenem MICs were lower (P< 0.0001) than those of imipenem and meropenem (MIC50s, 0.25, 2, and 0.38, respectively); 61%, 64%, and 70% were susceptible to imipenem, meropenem, and doripenem, respectively (Pwas not statistically significant). Factors independently associated with carbapenem resistance were previous carbapenem use (within 15 days) and mechanical ventilation duration before VAP onset. Fifty-six (33%) patients had at least one VAP recurrence, and 56 (33%) died. Factors independently associated with an unfavorable outcome (recurrence or death) were a high day 7 sequential organ failure assessment score and mechanical ventilation dependency on day 7. Physicians freely prescribed a carbapenem to 88 patients: imipenem for 32, meropenem for 24, and doripenem for 32. The remaining 81 patients were treated with various antibiotics. Imipenem-, meropenem-, and doripenem-treated patients had similar VAP recurrence rates (41%, 25%, and 22%, respectively; P= 0.15) and mortality rates (47%, 25%, and 22%, respectively; P= 0.07). Carbapenem resistance emerged similarly among patients treated with any carbapenem. No carbapenem was superior to another for preventing carbapenem resistance emergence.

Published
2014
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42. Human IgA binds a diverse array of commensal bacteria

Author

Sterlin, Delphine, Fadlallah, Jehane, Adams, Olivia, Fieschi, Claire, Parizot, Christophe, Dorgham, Karim, Rajkumar, Asok, Autaa, Gaëlle, El-Kafsi, Hela, Charuel, Jean-Luc, Juste, Catherine, Jönsson, Friederike, Candela, Thomas, Wardemann, Hedda, Aubry, Alexandra, Capito, Carmen, Brisson, Hélène, Tresallet, Christophe, Cummings, Richard D., Larsen, Martin, Yssel, Hans, von Gunten, Stephan, and Gorochov, Guy

Abstract

In humans, several grams of IgA are secreted every day in the intestinal lumen. While only one IgA isotype exists in mice, humans secrete IgA1 and IgA2, whose respective relations with the microbiota remain elusive. We compared the binding patterns of both polyclonal IgA subclasses to commensals and glycan arrays and determined the reactivity profile of native human monoclonal IgA antibodies. While most commensals are dually targeted by IgA1 and IgA2 in the small intestine, IgA1+IgA2+ and IgA1−IgA2+ bacteria coexist in the colon lumen, where Bacteroidetes is preferentially targeted by IgA2. We also observed that galactose-α terminated glycans are almost exclusively recognized by IgA2. Although bearing signs of affinity maturation, gut-derived IgA monoclonal antibodies are cross-reactive in the sense that they bind to multiple bacterial targets. Private anticarbohydrate-binding patterns, observed at clonal level as well, could explain these apparently opposing features of IgA, being at the same time cross-reactive and selective in its interactions with the microbiota.

Published
2020
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43. Human IgA binds a diverse array of commensal bacteria

Author

Sterlin, Delphine, Fadlallah, Jehane, Adams, Olivia, Fieschi, Claire, Parizot, Christophe, Dorgham, Karim, Rajkumar, Asok, Autaa, Gaëlle, El-Kafsi, Hela, Charuel, Jean-Luc, Juste, Catherine, Jönsson, Friederike, Candela, Thomas, Wardemann, Hedda, Aubry, Alexandra, Capito, Carmen, Brisson, Hélène, Tresallet, Christophe, Cummings, Richard D, Larsen, Martin, Yssel, Hans, Von Gunten, Stephan, and Gorochov, Guy

Subjects
fluids and secretions, stomatognathic system, 610 Medicine & health, 3. Good health
Abstract

In humans, several grams of IgA are secreted every day in the intestinal lumen. While only one IgA isotype exists in mice, humans secrete IgA1 and IgA2, whose respective relations with the microbiota remain elusive. We compared the binding patterns of both polyclonal IgA subclasses to commensals and glycan arrays and determined the reactivity profile of native human monoclonal IgA antibodies. While most commensals are dually targeted by IgA1 and IgA2 in the small intestine, IgA1+IgA2+ and IgA1-IgA2+ bacteria coexist in the colon lumen, where Bacteroidetes is preferentially targeted by IgA2. We also observed that galactose-α terminated glycans are almost exclusively recognized by IgA2. Although bearing signs of affinity maturation, gut-derived IgA monoclonal antibodies are cross-reactive in the sense that they bind to multiple bacterial targets. Private anticarbohydrate-binding patterns, observed at clonal level as well, could explain these apparently opposing features of IgA, being at the same time cross-reactive and selective in its interactions with the microbiota.

44. Intensive care unit-acquired Stenotrophomonas maltophilia: incidence, risk factors, and outcome

Author

Nseir, Saad, Di Pompeo, Christophe, Brisson, Hélène, Dewavrin, Florent, Tissier, Stéphanie, Diarra, Maimouna, Boulo, Marie, and Durocher, Alain

Abstract

Introduction The aim of this study was to determine incidence, risk factors, and impact on outcome of intensive care unit (ICU)-acquired Stenotrophomonas maltophilia.Methods This prospective observational case-control study, which was a part of a cohort study, was conducted in a 30-bed ICU during a three year period. All immunocompetent patients hospitalised >48 hours were eligible. Patients with non-fermenting Gram-negative bacilli (NF-GNB) at ICU admission were excluded. Patients without ICU-acquired S. maltophilia who developed an ICU-acquired NF-GNB other than S. maltophilia were also excluded. Screening (tracheal aspirate and skin, anal, and nasal swabs) for NF-GNB was performed in all patients at ICU admission and weekly. Univariate and multivariate analyses were performed to determine risk factors for ICU-acquired S. maltophilia and for ICU mortality.Results Thirty-eight (2%) patients developed an S. maltophilia ICU-acquired colonisation and/or infection and were all successfully matched with 76 controls. Chronic obstructive pulmonary disease (COPD) and duration of antibiotic treatment (odds ratio [OR] [95% confidence interval (CI)] = 9.4 [3 to 29], p < 0.001, and 1.4 [1 to 2.3], p = 0.001, respectively) were independently associated with ICU-acquired S. maltophilia. Mortality rate (60% versus 40%, OR [95% CI] = 1.3 [1 to 1.7, p = 0.037]), duration of mechanical ventilation (23 ± 16 versus 7 ± 11 days, p < 0.001), and duration of ICU stay (29 ± 21 versus 15 ± 17 days, p < 0.001) were significantly higher in cases than in controls. In addition, ICU-acquired infection related to S. maltophilia was independently associated with ICU mortality (OR [95% CI] = 2.8 [1 to 7.7], p = 0.044).Conclusion COPD and duration of antibiotic treatment are independent risk factors for ICU-acquired S. maltophilia. ICU-acquired S. maltophilia is associated with increased morbidity and mortality rates. ICU-acquired infection related to S. maltophilia is an independent risk factor for ICU mortality.

Published
2006
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45. [Multidisciplinarity and early rehabilitation in intensive care].

Author

Brisson H, Guérin L, and Kacer S

Subjects
Humans, Time Factors, Critical Care organization & administration, Patient Care Team, Rehabilitation methods
Abstract

Whatever the nature of the mobilisation of intensive care patients, it requires sufficient numbers of staff, time and adapted material resources. It forms part of the personalised treatment around the patient's care project. Mobilising patients as soon as possible in order to enable them to recover a minimum of muscle tone is the first stage before standing with a view to their early recovery of their lost autonomy. The in-bed cycle is one of the tools of this care project., (Copyright © 2018 Elsevier Masson SAS. All rights reserved.)

Published
2018
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46. Aerosolized antibiotics for ventilator-associated pneumonia: lessons from experimental studies.

Author

Rouby JJ, Bouhemad B, Monsel A, Brisson H, Arbelot C, and Lu Q

Subjects
Administration, Inhalation, Animals, Humans, Nebulizers and Vaporizers standards, Pneumonia, Ventilator-Associated microbiology, Respiration, Artificial adverse effects, Respiration, Artificial standards, Anti-Bacterial Agents administration & dosage, Pneumonia, Ventilator-Associated drug therapy
Abstract

The aim of this review is to perform a critical analysis of experimental studies on aerosolized antibiotics and draw lessons for clinical use in patients with ventilator-associated pneumonia. Ultrasonic or vibrating plate nebulizers should be preferred to jet nebulizers. During the nebulization period, specific ventilator settings aimed at decreasing flow turbulence should be used, and discoordination with the ventilator should be avoided. The appropriate dose of aerosolized antibiotic can be determined as the intravenous dose plus extrapulmonary deposition. If these conditions are strictly respected, then high lung tissue deposition associated with rapid and efficient bacterial killing can be expected. For aerosolized aminoglycosides and cephalosporins, a decrease in systemic exposure leading to reduced toxicity is not proven by experimental studies. Aerosolized colistin, however, does not easily cross the alveolar-capillary membrane even in the presence of severe lung infection, and high doses can be delivered by nebulization without significant systemic exposure.

Published
2012
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47. Activation of peroxisome proliferator-activated receptor-alpha by fenofibrate prevents myocardial dysfunction during endotoxemia in rats.

Author

Jozefowicz E, Brisson H, Rozenberg S, Mebazaa A, Gelé P, Callebert J, Lebuffe G, Vallet B, Bordet R, and Tavernier B

Subjects
Actin Cytoskeleton drug effects, Actin Cytoskeleton physiology, Animals, Calcium metabolism, Endotoxins immunology, Lipopolysaccharides immunology, Male, Myocardial Contraction physiology, Nitric Oxide metabolism, Oxidative Stress physiology, Premedication, Rats, Rats, Wistar, Tumor Necrosis Factor-alpha metabolism, Fenofibrate pharmacology, Hypolipidemic Agents pharmacology, Myocardial Contraction drug effects, PPAR alpha drug effects, Ventricular Dysfunction, Left physiopathology
Abstract

Objective: To investigate the effects of fenofibrate, an activator of peroxisome proliferator-activated receptor-alpha, on cardiac function in a rat endotoxemia model., Design: Prospective, randomized, controlled study., Setting: University research laboratory., Subjects: Three-month-old male Wistar rats., Interventions: Animals were fed with standard diet containing no drug or fenofibrate (0.2%) for 14 days. They were then injected intravenously with either 5 mg/kg lipopolysaccharide (LPS and fenofibrate + LPS groups) or saline (control and fenofibrate groups)., Measurements and Main Results: In the LPS group, body weight loss, metabolic acidosis, and thrombocytopenia confirmed presence of systemic endotoxemia. LPS administration resulted in an early peak in plasma tumor necrosis factor-alpha, decreased cardiac contractility (isolated and perfused heart), reduced myofilament Ca2+ sensitivity (Triton-skinned cardiac fibers), and increased left ventricular nitric oxide (NO) end-oxidation products (NO(x) and NO2), without evidence of myocardial oxidative stress (thiobarbituric acid-reactive substances and antioxidant enzyme activities). Fenofibrate pretreatment (fenofibrate + LPS group) did not alter signs of endotoxemia but prevented reductions in both cardiac contractility and myofilament Ca2+ sensitivity. The peak of plasma tumor necrosis factor-alpha was attenuated, whereas myocardial NO(x) and NO2 remained similar to the LPS group. Oxidative stress was suggested from moderate increase in cardiac thiobarbituric acid-reactive substances and reduced glutathione peroxidase activity., Conclusion: Fenofibrate, an activator of peroxisome proliferator-activated receptor-alpha, may prevent endotoxemia-induced cardiac dysfunction and reduction in myofilament Ca2+ sensitivity. Our data also suggest a mediating role for early peak plasma tumor necrosis factor-alpha, but not for myocardial NO production or oxidative stress.

Published
2007
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