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1. The Prognostic Role of the Number of Involved Structures in Thymic Epithelial Tumors: Results from the ESTS Database

Author

Chiappetta, Marco, Lococo, Filippo, Sassorossi, Carolina, Aigner, Clemens, Ploenes, Till, Van Raemdonck, Dirk, Vanluyten, Cedric, Van Schil, Paul, Agrafiotis, Apostolos C., Guerrera, Francesco, Lyberis, Paraskevas, Casiraghi, Monica, Spaggiari, Lorenzo, Zisis, Charalambos, Magou, Christina, Moser, Bernhard, Bauer, Jonas, Thomas, Pascal Alexandre, Brioude, Geoffrey, Passani, Stefano, Zsanto, Zalan, Sperduti, Isabella, and Margaritora, Stefano

Published
2024
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2. ASO Visual Abstract: The Prognostic Role of the Number of Involved Structures in Thymic Epithelial Tumors: Results from the ESTS Database

Author

Chiappetta, Marco, Lococo, Filippo, Sassorossi, Carolina, Aigner, Clemens, Ploenes, Till, Van Raemdonck, Dirk, Vanluyten, Cedric, Van Schil, Paul, Agrafiotis, Apostolos, Guerrera, Francesco, Lyberis, Paraskevas, Casiraghi, Monica, Spaggiari, Lorenzo, Zisis, Charalambos, Magou, Christina, Moser, Bernhard, Bauer, Jonas, Thomas, Pascal Alexandre, Brioude, Geoffrey, Passani, Stefano, Zsanto, Zalan, Sperduti, Isabella, and Margaritora, Stefano

Published
2024
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3. ASO Author Reflections: The Number of Involved Structures is a Promising Prognostic Factor in Thymic Epithelial Tumors

Author

Chiappetta, Marco, Lococo, Filippo, Sassorossi, Carolina, Aigner, Clemens, Ploenes, Till, Van Raemdonck, Dirk, Vanluyten, Cedric, Van Schil, Paul, Agrafiotis, Apostolos, Guerrera, Francesco, Lyberis, Paraskevas, Casiraghi, Monica, Spaggiari, Lorenzo, Zisis, Charalambos, Magou, Christina, Moser, Bernhard, Bauer, Jonas, Thomas, Pascal Alexandre, Brioude, Geoffrey, Passani, Stefano, Zsanto, Zalan, Sperduti, Isabella, and Margaritora, Stefano

Published
2024
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4. Correction: ASO Author Reflections: The Number of Involved Structures is a Promising Prognostic Factor in Thymic Epithelial Tumors

Author

Chiappetta, Marco, Lococo, Filippo, Sassorossi, Carolina, Aigner, Clemens, Ploenes, Till, Van Raemdonck, Dirk, Vanluyten, Cedric, Van Schil, Paul, Agrafiotis, Apostolos, Guerrera, Francesco, Lyberis, Paraskevas, Casiraghi, Monica, Spaggiari, Lorenzo, Zisis, Charalambos, Magou, Christina, Moser, Bernhard, Bauer, Jonas, Thomas, Pascal Alexandre, Brioude, Geoffrey, Passani, Stefano, Zsanto, Zalan, Sperduti, Isabella, and Margaritora, Stefano

Published
2024
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5. Correction: The Prognostic Role of the Number of Involved Structures in Thymic Epithelial Tumors: Results from the ESTS Database

Author

Chiappetta, Marco, Lococo, Filippo, Sassorossi, Carolina, Aigner, Clemens, Ploenes, Till, Van Raemdonck, Dirk, Vanluyten, Cedric, Van Schil, Paul, Agrafiotis, Apostolos C., Guerrera, Francesco, Lyberis, Paraskevas, Casiraghi, Monica, Spaggiari, Lorenzo, Zisis, Charalambos, Magou, Christina, Moser, Bernhard, Bauer, Jonas, Thomas, Pascal Alexandre, Brioude, Geoffrey, Passani, Stefano, Zsanto, Zalan, Sperduti, Isabella, and Margaritora, Stefano

Published
2024
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6. Correction: ASO Visual Abstract: The Prognostic Role of the Number of Involved Structures in Thymic Epithelial Tumors: Results from the ESTS Database

Author

Chiappetta, Marco, Lococo, Filippo, Sassorossi, Carolina, Aigner, Clemens, Ploenes, Till, Van Raemdonck, Dirk, Vanluyten, Cedric, Van Schil, Paul, Agrafiotis, Apostolos, Guerrera, Francesco, Lyberis, Paraskevas, Casiraghi, Monica, Spaggiari, Lorenzo, Zisis, Charalambos, Magou, Christina, Moser, Bernhard, Bauer, Jonas, Thomas, Pascal Alexandre, Brioude, Geoffrey, Passani, Stefano, Zsanto, Zalan, Sperduti, Isabella, and Margaritora, Stefano

Published
2024
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7. Recommendations for Post-Operative RadioTherapy After Complete Resection of Thymoma—a French DELPHI Consensus Initiative

Author

Basse, Clémence, Khalifa, Jonathan, Thillays, François, Le Pechoux, Cécile, Maury, Jean-Michel, Bonte, Pierre-Emmanuel, Coutte, Alexandre, Pourel, Nicolas, Bourbonne, Vincent, Pradier, Olivier, Belliere, Aurélie, Le Tinier, Florence, Deberne, Mélanie, Tanguy, Ronan, Denis, Fabrice, Padovani, Laetitia, Zaccariotto, Audrey, Molina, Thierry, Chalabreysse, Lara, Brioude, Geoffrey, Delatour, Bertrand, Faivre, Jean-Christophe, Cao, Kim, Giraud, Philippe, Riet, François-Georges, Thureau, Sébastien, Antoni, Delphine, Massabeau, Carole, Keller, Audrey, Bonnet, Emilie, Lerouge, Delphine, Martin, Etienne, Girard, Nicolas, and Botticella, Angela

Published
2024
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9. 2022 Update of indications and contraindications for lung transplantation in France

Author

Le Pavec, Jérôme, Pison, Christophe, Hirschi, Sandrine, Bunel, Vincent, Mordant, Pierre, Brugière, Olivier, Guen, Morgan Le, Olland, Anne, Coiffard, Benjamin, Renaud-Picard, Benjamin, Tissot, Adrien, Brioude, Geoffrey, Borie, Raphaël, Crestani, Bruno, Deslée, Gaétan, Stelianides, Sandrine, Mal, Hervé, Schuller, Armelle, Falque, Loïc, Lorillon, Gwenaëlle, Tazi, Abdellatif, Burgel, Pierre Regis, Grenet, Dominique, De Miranda, Sandra, Bergeron, Anne, Launay, David, Cottin, Vincent, Nunes, Hilario, Valeyre, Dominique, Uzunhan, Yurdagul, Prévot, Grégoire, Sitbon, Olivier, Montani, David, Savale, Laurent, Humbert, Marc, Fadel, Elie, Mercier, Olaf, Mornex, Jean François, Dauriat, Gaëlle, and Reynaud-Gaubert, Martine

Published
2023
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12. Refractory Pseudomonas aeruginosa Bronchopulmonary Infection After Lung Transplantation for Common Variable Immunodeficiency Despite Maximal Treatment Including IgM/IgA-Enriched Immunoglobulins and Bacteriophage Therapy

Author

Levêque, Manon, primary, Cassir, Nadim, additional, Mathias, Fanny, additional, Fevre, Cindy, additional, Daviet, Florence, additional, Bermudez, Julien, additional, Brioude, Geoffrey, additional, Peyron, Florence, additional, Reynaud-Gaubert, Martine, additional, and Coiffard, Benjamin, additional

Published
2023
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13. Prediction of survival after lung transplantation at one year (SALTO cohort) using information available at different key time-points

Author

Belaroussi, Yaniss, primary, Hustache-Castaing, Romain, additional, Maury, Jean-Michel, additional, Lehot, Laurent, additional, Rodriguez, Arnaud, additional, Demant, Xavier, additional, Rozé, Hadrien, additional, Brioude, Geoffrey, additional, D’Journo, Xavier-Benoit, additional, Drevet, Gabrielle, additional, Tronc, Francois, additional, Mathoulin-Pélissier, Simone, additional, Jougon, Jacques, additional, Thomas, Pascal-Alexandre, additional, and Thumerel, Matthieu, additional

Published
2023
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14. Effectiveness of Surgeon-Performed Paravertebral Block Analgesia for Minimally Invasive Thoracic Surgery: A Randomized Clinical Trial.

Author

Chenesseau, Josephine, Fourdrain, Alex, Pastene, Bruno, Charvet, Aude, Rivory, Adrien, Baumstarck, Karine, Bouabdallah, Ilies, Trousse, Delphine, Boulate, David, Brioude, Geoffrey, Gust, Lucile, Vasse, Matthieu, Braggio, Cesare, Mora, Pierre, Labarriere, Ambroise, Zieleskiewicz, Laurent, Leone, Marc, Thomas, Pascal Alexandre, and D'Journo, Xavier-Benoit

Published
2023
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15. Refractory Pseudomonas aeruginosa Bronchopulmonary Infection After Lung Transplantation for Common Variable Immunodeficiency Despite Maximal Treatment Including IgM/IgA-Enriched Immunoglobulins and Bacteriophage Therapy

Author

Levêque,Manon, Cassir,Nadim, Mathias,Fanny, Fevre,Cindy, Daviet,Florence, Bermudez,Julien, Brioude,Geoffrey, Peyron,Florence, Reynaud-Gaubert,Martine, and Coiffard,Benjamin

Subjects
Infection and Drug Resistance
Abstract

Manon Levêque,1 Nadim Cassir,2 Fanny Mathias,3 Cindy Fevre,4 Florence Daviet,5 Julien Bermudez,1 Geoffrey Brioude,6 Florence Peyron,3 Martine Reynaud-Gaubert,1 Benjamin Coiffard1 1Department of Respiratory Medicine and Lung Transplantation, APHM, Aix Marseille University, Hôpital Nord, Marseille, France; 2Department of Infectious Disease, APHM, IHU Méditerranée Infection, Aix-Marseille University, Marseille, France; 3Department of Pharmacy, APHM, Aix Marseille University, Hôpital Nord, Marseille, France; 4Research and Development, Pherecydes Pharma, Romainville, France; 5Intensive Care Medicine, APHM, Aix Marseille University, Hôpital Nord, Marseille, France; 6Department of Thoracic Surgery and Lung Transplantation, APHM, Aix Marseille University, Hôpital Nord, Marseille, FranceCorrespondence: Benjamin Coiffard, Department of Respiratory Medicine and Lung Transplantation, APHM, CHU Nord, Chemin des Bourrely, Marseille, 13915, France, Tel +33491966133, Email benjamin.coiffard@ap-hm.frAbstract: Recipients transplanted for bronchiectasis in the context of a primary immune deficiency, such as common variable immunodeficiency, are at a high risk of severe infection in post-transplantation leading to poorer long-term outcomes than other transplant indications. In this report, we present a fatal case due to chronic Pseudomonas aeruginosa bronchopulmonary infection in a lung transplant recipient with common variable immunodeficiency despite successful eradication of an extensively drug-resistant (XDR) strain with IgM/IgA-enriched immunoglobulins and bacteriophage therapy. The fatal evolution despite a drastic adaptation of the immunosuppressive regimen and the maximal antibiotic therapy strategy raises the question of the contraindication of lung transplantation in such a context of primary immunodeficiency.Keywords: primary immunodeficiency diseases, lung transplantation, Pseudomonas aeruginosa, phage therapy, immunoglobulin therapy

Published
2023

16. Lung Transplantation for Primary Ciliary Dyskinesia and Kartagener Syndrome: A Multicenter Study

Author

Marro, Matteo, primary, Leiva-Juárez, Miguel M., additional, D’Ovidio, Frank, additional, Chan, Justin, additional, Van Raemdonck, Dirk, additional, Ceulemans, Laurens Joseph, additional, Moreno, Paula, additional, Kindelan, Antonio Alvarez, additional, Krueger, Thorsten, additional, Koutsokera, Angela, additional, Ehrsam, Jonas Peter, additional, Inci, Ilhan, additional, Yazicioglu, Alkin, additional, Yekeler, Erdal, additional, Boffini, Massimo, additional, Brioude, Geoffrey, additional, Thomas, Pascal Alexandre, additional, Pizanis, Nikolaus, additional, Aigner, Clemens, additional, Schiavon, Marco, additional, Rea, Federico, additional, Anile, Marco, additional, Venuta, Federico, additional, and Keshavjee, Shaf, additional

Published
2023
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17. Lung Transplantation for Primary Ciliary Dyskinesia and Kartagener Syndrome : A Multicenter Study

Author

Marro, Matteo, Leiva-Juárez, Miguel M., D'Ovidio, Frank, Chan, Justin, Van Raemdonck, Dirk, Ceulemans, Laurens Joseph, Moreno, Paula, Kindelan, Antonio Alvarez, Krueger, Thorsten, Koutsokera, Angela, Ehrsam, Jonas Peter, Inci, Ilhan, Yazicioglu, Alkin, Yekeler, Erdal, Boffini, Massimo, Brioude, Geoffrey, Thomas, Pascal Alexandre, Pizanis, Nikolaus, Aigner, Clemens, Schiavon, Marco, Rea, Federico, Anile, Marco, Venuta, Federico, Keshavjee, Shaf, and D’Ovidio, Frank

Subjects
Transplantation, Kartagener Syndrome, Biopsy, Data Collection, primary graft dysfunction, Medizin, rare disease, Humans, outcomes, lung transplant, chronic lung allograft dysfunction, Retrospective Studies, Lung Transplantation
Abstract

Primary ciliary dyskinesia, with or without situs abnormalities, is a rare lung disease that can lead to an irreversible lung damage that may progress to respiratory failure. Lung transplant can be considered in end-stage disease. This study describes the outcomes of the largest lung transplant population for PCD and for PCD with situs abnormalities, also identified as Kartagener's syndrome. Retrospectively collected data of 36 patients who underwent lung transplantation for PCD from 1995 to 2020 with or without SA as part of the European Society of Thoracic Surgeons Lung Transplantation Working Group on rare diseases. Primary outcomes of interest included survival and freedom from chronic lung allograft dysfunction. Secondary outcomes included primary graft dysfunction within 72 h and the rate of rejection ≥A2 within the first year. Among PCD recipients with and without SA, the mean overall and CLAD-free survival were 5.9 and 5.2 years with no significant differences between groups in terms of time to CLAD (HR: 0.92, 95% CI: 0.27-3.14, p = 0.894) or mortality (HR: 0.45, 95% CI: 0.14-1.43, p = 0.178). Postoperative rates of PGD were comparable between groups; rejection grades ≥A2 on first biopsy or within the first year was more common in patients with SA. This study provides a valuable insight on international practices of lung transplantation in patients with PCD. Lung transplantation is an acceptable treatment option in this population. ispartof: TRANSPLANT INTERNATIONAL vol:36 ispartof: location:Switzerland status: published

Published
2023

18. Benignant and malignant epidemiology among surgical resections for suspicious solitary lung cancer without preoperative tissue diagnosis

Author

Armand, Elsa, primary, Boulate, David, additional, Fourdrain, Alex, additional, Nguyen, Ngoc-Anh-Thu, additional, Resseguier, Noémie, additional, Brioude, Geoffrey, additional, Trousse, Delphine, additional, Doddoli, Christophe, additional, D’journo, Xavier-Benoit, additional, and Thomas, Pascal-Alexandre, additional

Published
2022
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19. Prediction of survival after a lung transplant at 1 year (SALTO cohort) using information available at different key time points.

Author

Belaroussi, Yaniss, Hustache-Castaing, Romain, Maury, Jean-Michel, Lehot, Laurent, Rodriguez, Arnaud, Demant, Xavier, Rozé, Hadrien, Brioude, Geoffrey, D'Journo, Xavier-Benoit, Drevet, Gabrielle, Tronc, Francois, Mathoulin-Pélissier, Simone, Jougon, Jacques, Thomas, Pascal-Alexandre, and Thumerel, Matthieu

Subjects
LUNG transplantation, RECEIVER operating characteristic curves, KIDNEY transplantation, Q fever
Abstract

Open in new tab Download slide OBJECTIVES A lung transplant is the final treatment option for end-stage lung disease. We evaluated the individual risk of 1-year mortality at each stage of the lung transplant process. METHODS This study was a retrospective analysis of patients undergoing bilateral lung transplants between January 2014 and December 2019 in 3 French academic centres. Patients were randomly divided into development and validation cohorts. Three multivariable logistic regression models of 1-year mortality were applied (i) at recipient registration, (ii) the graft allocation and (iii) after the operation. The 1-year mortality was predicted for individual patients assigned to 3 risk groups at time points A to C. RESULTS The study population consisted of 478 patients with a mean (standard deviation) age of 49.0 (14.3) years. The 1-year mortality rate was 23.0%. There were no significant differences in patient characteristics between the development (n  =   319) and validation (n  =   159) cohorts. The models analysed recipient, donor and intraoperative variables. The discriminatory power (area under the receiver operating characteristic curve) was 0.67 (0.62–0.73), 0.70 (0.63–0.77) and 0.82 (0.77–0.88), respectively, in the development cohort and 0.74 (0.64–0.85), 0.76 (0.66–0.86) and 0.87 (0.79 – 0.95), respectively, in the validation cohort. Survival rates were significantly different among the low- (< 15%), intermediate- (15%–45%) and high-risk (> 45%) groups in both cohorts. CONCLUSIONS Risk prediction models allow estimation of the 1-year mortality risk of individual patients during the lung transplant process. These models may help caregivers identify high-risk patients at times A to C and reduce the risk at subsequent time points. [ABSTRACT FROM AUTHOR]

Published
2023
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20. Ultra-early initiation of postoperative rehabilitation in the post-anaesthesia care unit after major thoracic surgery: case-control study

Author

Pastene, Bruno, Labarriere, Ambroise, Lopez, Alexandre, Charvet, Aude, Culver, Aurélien, Fiocchi, David, Cluzel, Armand, Brioude, Geoffrey, Einav, Sharon, Tankel, James, Hamidou, Zeinab, D’journo, Xavier Benoit, Thomas, Pascal, Leone, Marc, Zieleskiewicz, Laurent, Slim, K., Joris, J., Delaunay, L., Regimbeau, J-M., Ostermann, S., Beyer-Berjot, L., Lavand'Homme, P., Lafortune, I., Szymkiewicz, O., Venara, A., Zieleskiewicz, L., Puppo, N., Beaupère, S., Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), CHU Marseille, Aix-Marseille Université - École de médecine (AMU SMPM MED), Aix-Marseille Université - Faculté des sciences médicales et paramédicales (AMU SMPM), Aix Marseille Université (AMU)-Aix Marseille Université (AMU), Hôpital Nord [CHU - APHM], The Hebrew University of Jerusalem (HUJ), McGill University = Université McGill [Montréal, Canada], Centre d'études et de recherche sur les services de santé et la qualité de vie (CEReSS), Aix Marseille Université (AMU), Hôpital de la Timone [CHU - APHM] (TIMONE), CHU Clermont-Ferrand, Centre Hospitalier Universitaire de Liège (CHU-Liège), Clinique Générale Annecy, CHU Amiens-Picardie, Université de Genève = University of Geneva (UNIGE), Cliniques Universitaires Saint-Luc [Bruxelles], Hospices Civils de Lyon (HCL), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), CHU d'Angers [Département Urgences], Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM), Hôpital Saint-Joseph [Marseille], UNICANCER, and Lucas, Nelly

Subjects
Pulmonary Atelectasis, Postoperative Complications, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, [SDV.MHEP.CHI] Life Sciences [q-bio]/Human health and pathology/Surgery, Case-Control Studies, Humans, Thoracic Surgery, Anesthesia, General Medicine, [SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery, Pneumonia, [SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system
Abstract

Background Physiotherapy is a major cornerstone of enhanced rehabilitation after surgery (ERAS) and reduces the development of atelectasis after thoracic surgery. By initiating physiotherapy in the post-anaesthesia care unit (PACU), the aim was to evaluate whether the ultra-early initiation of rehabilitation (in the first hour following tracheal extubation) would improve the outcomes of patients undergoing elective thoracic surgery. Methods A case–control study with a before-and-after design was conducted. From a historical control group, patients were paired at a 3:1 ratio with an intervention group. This group consisted of patients treated with the ultra-early rehabilitation programme after elective thoracic surgery (clear fluids, physiotherapy, and ambulation). The primary outcome was the incidence of postoperative atelectasis and/or pneumonia during the hospital stay. Results After pairing, 675 patients were allocated to the historical control group and 225 patients to the intervention group. A significant decrease in the incidence of postoperative atelectasis and/or pneumonia was found in the latter (11.4 versus 6.7 per cent respectively; P = 0.042) and remained significant on multivariate analysis (OR 0.53, 95 per cent c.i. 0.26 to 0.98; P = 0.045). A subgroup analysis of the intervention group showed that early ambulation during the PACU stay was associated with a further significant decrease in the incidence of postoperative atelectasis and/or pneumonia (2.2 versus 9.5 per cent; P = 0.012). Conclusions Ultra-early rehabilitation in the PACU was associated with a decrease in the incidence of postoperative atelectasis and/or pneumonia after major elective thoracic surgery.

Published
2022

22. Benignant and malignant epidemiology among surgical resections for suspicious solitary lung cancer without preoperative tissue diagnosis.

Author

Armand, Elsa, Boulate, David, Fourdrain, Alex, Nguyen, Ngoc-Anh-Thu, Resseguier, Noémie, Brioude, Geoffrey, Trousse, Delphine, Doddoli, Christophe, D'journo, Xavier-Benoit, and Thomas, Pascal-Alexandre

Subjects
SURGICAL excision, LUNG cancer, EPIDEMIOLOGY, DATABASES, LOGISTIC regression analysis
Abstract

Open in new tab Download slide OBJECTIVES The aim of this study was to describe the epidemiology of patients undergoing diagnostic and/or curative surgical pulmonary resections for lung opacities suspected of being localized primary lung cancers without preoperative tissue confirmation. METHODS We performed a single-centre retrospective study of a prospectively implemented institutional database of all patients who underwent pulmonary resection between January 2010 and December 2020. Patients were selected when surgery complied with the Fleischner society guidelines. We performed a multivariable logistic regression to determine the preoperative variables associated with malignancy. RESULTS Among 1392 patients, 213 (15.3%) had a final diagnosis of benignancy. We quantified futile parenchymal resections in 29 (2.1%) patients defined by an anatomical resection of >2 lung segments for benign lesions that did not modified the clinical management. Compared with patients with malignancies, patients with benignancies were younger (57.5 vs 63.9 years, P  < 0.001), had lower preoperative risk profile (thoracoscore 0.4 vs 2.1, P  < 0.001), had a higher proportion of wedge resection (50.7% vs 12.2%, P  < 0.01) and experienced a lower burden of postoperative complication (Clavien–Dindo IV or V, 0.4% vs 5.6%, P  < 0.001). Preoperative independent variables associated with malignancy were (adjusted odd ratio [95% confident interval]) age 1.02 [1.00; 1.04], smoking (year-pack) 1.005 (1.00; 1.01), history of cardiovascular disease 2.06 [1.30; 3.30], history of controlled cancer 2.74 [1.30; 6.88] and clinical N involvement 4.20 [1.11; 37.44]. CONCLUSIONS Futile parenchymal lung resection for suspicious opacities without preoperative tissue diagnosis is rare (2.1%) while surgery for benign lesions represented 15.3% and has a satisfactory safety profile with very low postoperative morbi-mortality. [ABSTRACT FROM AUTHOR]

Published
2023
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23. Extracorporeal life support as a bridge to pulmonary retransplantation: prognostic factors for survival in a multicentre cohort analysis

Author

Inci, Ilhan, primary, Ehrsam, Jonas Peter, additional, Van Raemdonck, Dirk, additional, Ceulemans, Laurens Joseph, additional, Krüger, Thorsten, additional, Koutsokera, Angela, additional, Schiavon, Marco, additional, Faccioli, Eleonora, additional, Nosotti, Mario, additional, Rosso, Lorenzo, additional, D’Ovidio, Frank, additional, Leiva-Juarez, Miguel, additional, Aigner, Clemens, additional, Slama, Alexis, additional, Saleh, Waleed, additional, Alkattan, Khaled Manaa, additional, Thomas, Pascal Alexandre, additional, Brioude, Geoffrey, additional, Benazzo, Alberto, additional, and Hoetzenecker, Konrad, additional

Published
2021
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24. Surgical resection of Masaoka stage III thymic epithelial tumours with great vessels involvement: a retrospective multicentric analysis from the European Society of Thoracic Surgeons thymic database

Author

Mendogni, Paolo, Toker, Alper, Moser, Bernhard, Trancho, Florentino Hernando, Aigner, Clemens, Bravio, Ivan Gomes, Novoa, Nuria Maria, Molins, Laureano, Costardi, Lorena, Voltolini, Luca, Ardò, Nicoletta Pia, Verdonck, Bram, Ampollini, Luca, Zisis, Charlambos, Barmin, Vitaly, Enyedi, Attila, Ruffini, Enrico, Van Raemdonck, Dirk, Thomas, Pascal-Alexandre, Weder, Walter, Rocco, Gaetano, Brunelli, Alessandro, Detterbeck, Frank C, Venuta, Federico, Falcoz, Pierre-Emmanuel, Tosi, Davide, Bonitta, Gianluca, Nosotti, Mario, Ozkan, Berker, Cımenoglu, Berk, Thanner, Jürgen, Olivero, Carlos Fraile, Alvarado, Rodriguez, Boada, Marc, Bongiolatti, Stefano, Sollitto, Francesco, Van Schil, Paul, Bocchialini, Giovanni, Brioude, Geoffrey, and European Association of Thoracic Surgeons (ESTS) Thymic Working Group

Subjects
Pulmonary and Respiratory Medicine, Surgeons, recurrence, Vena Cava, Superior, Thymoma, great vessels, survival, thymectomy, thymic tumours, thymoma, Medizin, General Medicine, Thymus Neoplasms, Humans, Surgery, Human medicine, Neoplasms, Glandular and Epithelial, Cardiology and Cardiovascular Medicine, Neoplasm Staging, Retrospective Studies
Abstract

OBJECTIVES The aim of this study was to analyse the outcomes of an international cohort of patients affected by Masaoka stage III thymic epithelial tumours with vascular involvement and treated by surgery. METHODS Study design was the observational multicentre retrospective cohort study. Data were extracted from the European Society of Thoracic Surgeons thymic database; additional variables were collected. Inclusion criteria were as follows: stage III (Masaoka–Koga) thymic epithelial tumours; surgery with radical intention; clinical or pathological great vessels involvement; and radiologically suspected or diagnosed intraoperatively. Outcome items were analysed. RESULTS Sixty-five patients submitted to surgery from 2001 to 2017 fulfilled inclusion criteria. Thymoma and thymic carcinoma patients did not differ for demographics and clinical characteristics. The majority of great vessel treated were superior vena cava or innominate veins (72.3%). Eleven patients (16.9%) had postoperative cardiopulmonary complications; vascular stenosis was observed in 3 patients (4.6%). The multivariable Cox analysis for disease-free survival showed an increased hazard of recurrence for thymic carcinoma (hazard ratio = 3.59; 95% confidence interval: 1.66–7.78, P = 0.001). The 1-, 3-, 5- and 10-year overall survival rates were 0.86, 0.84, 0.81, and 0.53, respectively. There was no significant difference in overall survival according to resection status or between thymoma and thimic carcinoma. The univariable Cox regression model did not show an increased hazard of death for myasthenic patients considering all resection status and for patients who received neoadjuvant therapy. CONCLUSIONS We observed that clinical outcomes of patients treated for stage III thymic epithelial tumours with vascular involvement are satisfactory suggesting to increase the confidence in dealing with these complex surgeries. Complete resection should be achieved, even though extensive vascular reconstructions are required.

Published
2021

25. Corrigendum to ‘Thymomectomy plus total thymectomy versus simple thymomectomy for early-stage thymoma without myasthenia gravis: a European Society of Thoracic Surgeons Thymic Working Group Study’

Author

Guerrera, Francesco, primary, Falcoz, Pierre Emmanuel, additional, Moser, Bernhard, additional, van Raemdonck, Dirk, additional, Bille, Andrea, additional, Toker, Alper, additional, Spaggiari, Lorenzo, additional, Ampollini, Luca, additional, Filippini, Claudia, additional, Thomas, Pascal Alexandre, additional, Verdonck, Bram, additional, Mendogni, Paolo, additional, Aigner, Clemens, additional, Voltolini, Luca, additional, Novoa, Nuria, additional, Patella, Miriam, additional, Mantovani, Sara, additional, Bravio, Ivan Gomes, additional, Zisis, Charalambos, additional, Guirao, Angela, additional, Londero, Francesco, additional, Congregado, Miguel, additional, Rocco, Gaetano, additional, Pont, Bert Du, additional, Martucci, Nicola, additional, Esch, Matthias, additional, Brunelli, Alessandro, additional, Detterbeck, Frank C, additional, Venuta, Federico, additional, Weder, Walter, additional, Ruffini, Enrico, additional, Klepetko, Walter, additional, Olland, Anne, additional, DuPont, Bert, additional, Nonaka, Daisuke, additional, Ozkan, Berker, additional, Lo Iacono, Giorgio, additional, Braggio, Cesare, additional, Filosso, Pier Luigi, additional, Brioude, Geoffrey, additional, van Schil, Paul, additional, Nosotti, Mario, additional, Valdivia, Daniel, additional, Bongiolatti, Stefano, additional, Inci, Ilhan, additional, Dimitra, Rontogianni, additional, Sànchez, David, additional, Grossi, William, additional, Moreno-Merino, Sergio, additional, and Teschner, Martin, additional

Published
2021
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27. Oesophageal pressure as a surrogate of pleural pressure in mechanically ventilated patients

Author

Tilmont, Antoine, primary, Coiffard, Benjamin, additional, Yoshida, Takeshi, additional, Daviet, Florence, additional, Baumstarck, Karine, additional, Brioude, Geoffrey, additional, Hraiech, Sami, additional, Forel, Jean-Marie, additional, Roch, Antoine, additional, Brochard, Laurent, additional, Papazian, Laurent, additional, and Guervilly, Christophe, additional

Published
2021
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28. Extracorporeal life support as a bridge to pulmonary retransplantation: prognostic factors for survival in a multicentre cohort analysis.

Author

Inci, Ilhan, Ehrsam, Jonas Peter, Raemdonck, Dirk Van, Ceulemans, Laurens Joseph, Krüger, Thorsten, Koutsokera, Angela, Schiavon, Marco, Faccioli, Eleonora, Nosotti, Mario, Rosso, Lorenzo, D'Ovidio, Frank, Leiva-Juarez, Miguel, Aigner, Clemens, Slama, Alexis, Saleh, Waleed, Alkattan, Khaled Manaa, Thomas, Pascal Alexandre, Brioude, Geoffrey, Benazzo, Alberto, and Hoetzenecker, Konrad

Subjects
EXTRACORPOREAL membrane oxygenation, TRANSPLANTATION of organs, tissues, etc., PROGNOSIS, COHORT analysis, MORTALITY risk factors, REGRESSION analysis, OVERALL survival
Abstract

Open in new tab Download slide Open in new tab Download slide OBJECTIVES Pulmonary retransplant (ReTx) is considered a controversial procedure. Despite literature reporting outcomes following ReTx, limited data exist in recipients bridged to their ReTx on extracorporeal life support (ECLS). The goal of this study was to investigate the outcomes of recipients bridged to a first-time ReTx by ECLS. METHODS We performed a retrospective multicentre cohort analysis from 10 centres in Europe, Asia and North America. The primary outcome was overall survival. Risk factors were analysed using Cox regression models. RESULTS ECLS as a bridge to a first-time ReTx was performed in 50 recipients (ECLS-ReTx). During the study period, 210 recipients underwent a first-time ReTx without bridging on ECLS (regular-ReTx) and 4959 recipients had a primary pulmonary transplant (index-Tx). The overall 1-year (55%) and 5-year (29%) survival was significantly worse for the ECLS-ReTx group. Compared to the index-Tx group, the mortality risk was significantly higher after ECLS-ReTx [hazard ratio 2.76 (95% confidence interval 1.94–3.91); P  < 0.001] and regular-ReTx [hazard ratio 1.65 (95% confidence interval 1.36–2); P  < 0.001]. In multivariable analysis, recipient age ≥35 years, time interval <1 year from index-Tx, primary graft dysfunction as transplant indication, venoarterial-extracorporeal membrane oxygenation and Zurich donor score ≥4 points were significant risk factors for mortality in ECLS-ReTx recipients. CONCLUSIONS Recipients for ECLS-ReTx should be carefully selected. Risk factors, such as recipient age, intertransplant interval, primary graft dysfunction as transplant indication and type of ECLS should be kept in mind before bridging these patients on ECLS to ReTx. [ABSTRACT FROM AUTHOR]

Published
2022
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29. Screening and topical decolonization of preoperative nasal Staphylococcus aureus carriers to reduce the incidence of postoperative infections after lung cancer surgery: a propensity matched study

Author

Fourdrain, Alex, primary, Bouabdallah, Ilies, primary, Gust, Lucile, primary, Cassir, Nadim, primary, Brioude, Geoffrey, primary, Falcoz, Pierre-Emmanuel, primary, Alifano, Marco, primary, Le Rochais, Jean-Philippe, primary, D’Annoville, Thomas, primary, Trousse, Delphine, primary, Loundou, Anderson, primary, Leone, Marc, primary, Papazian, Laurent, primary, Thomas, Pascal Alexandre, primary, and D’Journo, Xavier Benoit, primary

Published
2019
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31. Lancement d’un programme de chirurgie thoracique robot-assistée : étude de la sécurité des soins et de la qualité dans le cadre de la courbe d’apprentissage

Author

De Lesquen, Henri, Bouabdallah, Ilies, Mège, Diane, David, Charles-Henri, Chenesseau, Joséphine, Gust, Lucile, Brioude, Geoffrey, Trousse, Delphine, D’Journo, Xavier-Benoit, Doddoli, Christophe, and Thomas, Pascal-Alexandre

Subjects
Thoracic surgery, VATS
Abstract

JCTCV:21(4), The purpose of this study was to compare our initial experience with RATS pulmonary lobectomy with that of our well-established VATS program. Methods: We compared the early outcomes of those 81 patients having had a 3-port full thoracoscopic lobectomy performed by the most experienced VATS surgeon with those 91 patients having had a 3-arm RATS lobectomy performed by a single surgeon during a 24-month period. Results: Operative time was longer in the RATS group (mean: 134.5 ± 154.2 minutes vs. 37.7 ± 47.3 minutes; p = 0.004). Overall morbidity was similar (43.4% vs. 39.1%; p = 0.57). Five patients in the VATS group required blood transfusions and only one in the RATS group (p = 0.12). Readmission rates at 90 days were similar (3.9% vs. 6.9%; p = 0.38). The 90-day mortality rates were 2.6% and 0% (p = 0.12). More N2 nodes were removed in the VATS group (mean: 9.92 ± 5.41 vs. 6.24 ± 5.584; p < 0.0001). The proportion of lymph node upstaging was similar in both groups (16% vs. 13%; p = 0.65). Conclusions: Our early experience of pulmonary lobectomy by RATS appears to be as safe and more mature than VATS, with regards to the 90-day postoperative period.

Published
2017
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32. Screening and topical decolonization of preoperative nasal Staphylococcus aureus carriers to reduce the incidence of postoperative infections after lung cancer surgery: a propensity matched study.

Author

Fourdrain, Alex, Bouabdallah, Ilies, Gust, Lucile, Cassir, Nadim, Brioude, Geoffrey, Falcoz, Pierre-Emmanuel, Alifano, Marco, Rochais, Jean-Philippe Le, D'Annoville, Thomas, Trousse, Delphine, Loundou, Anderson, Leone, Marc, Papazian, Laurent, Thomas, Pascal Alexandre, and D'Journo, Xavier Benoit

Published
2020
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34. Atrial anastomosis

Author

Gust, Lucile, primary, D’Journo, Xavier-Benoit, additional, Brioude, Geoffrey, additional, Trousse, Delphine, additional, Dizier, Stephanie, additional, Doddoli, Christophe, additional, Leone, Marc, additional, and Thomas, Pascal-Alexandre, additional

Published
2018
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35. Preparation of the hilum

Author

Gust, Lucile, primary, D’Journo, Xavier-Benoit, additional, Brioude, Geoffrey, additional, Trousse, Delphine, additional, Dizier, Stephanie, additional, Doddoli, Christophe, additional, Leone, Marc, additional, and Thomas, Pascal-Alexandre, additional

Published
2018
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36. Explantation of the native lung

Author

Gust, Lucile, primary, D’Journo, Xavier-Benoit, additional, Brioude, Geoffrey, additional, Trousse, Delphine, additional, Dizier, Stephanie, additional, Doddoli, Christophe, additional, Leone, Marc, additional, and Thomas, Pascal-Alexandre, additional

Published
2018
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37. Bronchial anastomosis

Author

Gust, Lucile, primary, D’Journo, Xavier-Benoit, additional, Brioude, Geoffrey, additional, Trousse, Delphine, additional, Dizier, Stephanie, additional, Doddoli, Christophe, additional, Leone, Marc, additional, and Thomas, Pascal-Alexandre, additional

Published
2018
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38. Lung dissection

Author

Gust, Lucile, primary, D’Journo, Xavier-Benoit, additional, Brioude, Geoffrey, additional, Trousse, Delphine, additional, Dizier, Stephanie, additional, Doddoli, Christophe, additional, Leone, Marc, additional, and Thomas, Pascal-Alexandre, additional

Published
2018
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39. Preparation of the graft

Author

Gust, Lucile, primary, D’Journo, Xavier-Benoit, additional, Brioude, Geoffrey, additional, Trousse, Delphine, additional, Dizier, Stephanie, additional, Doddoli, Christophe, additional, Leone, Marc, additional, and Thomas, Pascal-Alexandre, additional

Published
2018
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41. Retrograde flush

Author

Gust, Lucile, primary, D’Journo, Xavier-Benoit, additional, Brioude, Geoffrey, additional, Trousse, Delphine, additional, Dizier, Stephanie, additional, Doddoli, Christophe, additional, Leone, Marc, additional, and Thomas, Pascal-Alexandre, additional

Published
2018
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43. Mediastinal staging by videomediastinoscopy in clinical N1 non-small cell lung cancer: a prospective multicentre study

Author

Decaluwé, Herbert, primary, Dooms, Christophe, additional, D'Journo, Xavier Benoit, additional, Call, Sergi, additional, Sanchez, David, additional, Haager, Benedikt, additional, Beelen, Roel, additional, Kara, Volkan, additional, Klikovits, Thomas, additional, Aigner, Clemens, additional, Tournoy, Kurt, additional, Zahin, Mahmood, additional, Moons, Johnny, additional, Brioude, Geoffrey, additional, Trujillo, Juan Carlos, additional, Klepetko, Walter, additional, Turna, Akif, additional, Passlick, Bernward, additional, Molins, Laureano, additional, Rami-Porta, Ramon, additional, Thomas, Pascal, additional, and Leyn, Paul De, additional

Published
2017
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44. Surgical therapy of thymic tumours with pleural involvement: an ESTS Thymic Working Group Project†

Author

Moser, Bernhard, primary, Fadel, Elie, additional, Fabre, Dominique, additional, Keshavjee, Shaf, additional, de Perrot, Marc, additional, Thomas, Pascal, additional, Brioude, Geoffrey, additional, Van Raemdonck, Dirk, additional, Viskens, Sophie, additional, Lang-Lazdunski, Loic, additional, Bille, Andrea, additional, Weder, Walter, additional, Jungraithmayr, Wolfgang, additional, Ruffini, Enrico, additional, Guerrera, Francesco, additional, Gómez de Antonio, David, additional, Liberman, Moishe, additional, Novoa, Nuria, additional, Scarci, Marco, additional, Janik, Stefan, additional, and Klepetko, Walter, additional

Published
2017
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48. Journal of Thoracic Oncology Volume 8 Supplement 2 November 2013 WCLC 2013 Abstracts Official Publication of the International Association for the Study of Lung Cancer

Author

Filosso, Pier Luigi, Guerrera, Francesco, Ferolla, Piero, Pascal- Alexandre Thomas, Rea, Federico, Lucchi, Marco, Lococo, Filippo, Paul, Marinus A., Varela, Gonzalo, Ruffini, Enrico, Dell, Thomas Wad, Perrot, Marc De, Darling, Gail, Daddi, Nicolò, Puma, Francesco, Gridelli, Cesare, Brioude, Geoffrey, Marulli, Giuseppe, Bora, Giulia, Mussi, Alfredo, Margaritora, Stefano, Novoa, Nuria, and Shaf Keshavjiee

Published
2013
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