Search

Your search keyword '"Bridot, J.-L."' showing total 10 results
Start Over Author "Bridot, J.-L."
10 results on '"Bridot, J.-L."'

2. Nanoparticle containing rare earth ions: A tunable tool for MRI

Author

Rivière, C., Roux, S., Bazzi, R., Bridot, J.-L., Billotey, C., Perriat, P., Tillement, O., Laboratoire de Physique de la Matière Condensée et Nanostructures (LPMCN), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Univers, Transport, Interfaces, Nanostructures, Atmosphère et environnement, Molécules (UMR 6213) (UTINAM), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Laboratoire de Physico-Chimie des Matériaux Luminescents (LPCML), Physicochimie des Electrolytes, Colloïdes et Sciences Analytiques (PECSA), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université de Mons-Hainaut, Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé (CREATIS), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Groupe d'Etudes de Métallurgie Physique et Physique des Matériaux (GEMPPM), Institut National des Sciences Appliquées de Lyon (INSA Lyon), and Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[CHIM]Chemical Sciences
Published
2011

3. Gadolinium oxide hybrid nanoparticles: combining imagery and therapy

Author

Roux, S., Bridot, J. L., Dayde, D., Riviere, C., Billorey, C., Lepape, A., Marc Janier, Perriat, P., Tillement, O., Laboratoire de psychologie sociale et de psychologie cognitive (LAPSCO), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Centre National de la Recherche Scientifique (CNRS), Service de Réanimation (Nord), Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Centre de Recherche et d'Application en Traitement de l'Image et du Signal (CREATIS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-École Supérieure Chimie Physique Électronique de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Matériaux, ingénierie et science [Villeurbanne] (MATEIS), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physico-Chimie des Matériaux Luminescents (LPCML), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Centre National de la Recherche Scientifique (CNRS)-Université Blaise Pascal - Clermont-Ferrand 2 (UBP), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA), Université de Lyon-Université de Lyon-École Supérieure de Chimie Physique Électronique de Lyon (CPE)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), and Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)

Subjects
ComputingMilieux_MISCELLANEOUS, [SPI.MAT]Engineering Sciences [physics]/Materials
Abstract

International audience

Published
2008

4. Optimised synthetic route for tuneable shell Si02@Fe304 core-shell nanoparticles

Author

Vogt, Carmen M., Toprak, Muhammet, Shi, J., Torres, N. F., Fadeel, B., Laurent, S., Bridot, J. -L, Müller, R. N., Muhammed, Mamoun, Vogt, Carmen M., Toprak, Muhammet, Shi, J., Torres, N. F., Fadeel, B., Laurent, S., Bridot, J. -L, Müller, R. N., and Muhammed, Mamoun

Abstract

Multifunctional nanoparticles (that have in their structure different components that can perform various functions) are subject of intensive research activities as they find a large variety of applications in numerous biomedical fields from enhancement of image contrast in MRI to different magnetically controllable drug delivery systems. In this study we report on the synthesis of well-separated, monodisperse single core-shell Si02@Fe304 nanoparticles with an overall diameter of ̃30 nm. The influence of stirring rate and reaction time on synthesis of tuneable shell thickness core-shell nanoparticles is reported. Particles' cell toxicity and performance as MRI contrast agents were also studied due to their promising biological applications (as contrast agents, cell labelling and separation, drug delivery systems, etc.) and results are promising in terms of MRI performance as well as having no significant cytotoxicity., QC 20141014

Published
2009

6. CMR 2007: 7.07: Hybrid gadolinium oxide nanoparticles: contrast agents combining diagnosis and therapy

Author

Bridot, J.-L., primary, Dayde, D., additional, Faure, A.-C., additional, Laurent, S., additional, Rivière, C., additional, Billotey, C., additional, Hiba, B., additional, Janier, M., additional, Josserand, V., additional, Coll, J.-L., additional, Vander Elst, L., additional, Muller, R., additional, Sabattier, R., additional, Lerondel, S., additional, Lepape, A., additional, Perriat, P., additional, Roux, S., additional, and Tillement, O., additional

Published
2007
Full Text
View/download PDF

8. Nanosized Hybrid Particles with Double Luminescence for Biological Labeling

Author

Louis, C., Bazzi, R., Marquette, C. A., Bridot, J.-L., Roux, S., Ledoux, G., Mercier, B., Blum, L., Perriat, P., and Tillement, O.

Abstract

Doubly luminescent core/shell structure nanoparticles were synthesized for biological detection. In the first step gadolinium oxide (Gd2O3) core doped with the luminescent Tb3+ ions was obtained by applying, with modifications, the polyol route, which allows direct precipitation of oxide nanoparticles in a polyalcohol medium. The presence of Tb3+ ions in the Gd2O3 crystalline matrix confers attractive optical properties for long-term studies and multilabeling such as a high photostability and narrow emission bands. The water sensitivity of these particles, which is detrimental for the Tb ion's luminescence, was overcome by embedding the oxide core in a functionalized polysiloxane shell prepared by hydrolysis condensation of a mixture of APTES and TEOS. This protective layer allows the dispersion of the particles in aqueous solution without loss of luminescence intensity. Moreover, the luminescence of polysiloxane-coated Gd2O3 nanoparticles is more intense than that in the case of the naked Gd2O3 core. Due to the presence of amino groups, organic dyes and biotargeting groups (nucleic acid, biotin, streptavidin) were covalently linked to the polysiloxane network. These particles are efficient for detection of biomolecules whose presence is revealed by the high fluorescence of organic dyes and/or the photostable Tb3+ ion's luminescence.

Published
2005

9. Synthesis, Characterization of Dihydrolipoic Acid Capped Gold Nanoparticles, and Functionalization by the Electroluminescent Luminol

Author

Roux, S., Garcia, B., Bridot, J.-L., Salome, M., Marquette, C., Lemelle, L., Gillet, P., Blum, L., Perriat, P., and Tillement, O.

Abstract

The use of gold nanoparticles as biological probes requires the improvement of colloidal stability. Dihydrolipoic acid (DHLA), a dithiol obtained by the reduction of thioctic acid, appears therefore very attractive for the stabilization and the further functionalization of gold nanoparticles because DHLA is characterized by a carboxylic acid group and two thiol functions. The ionizable carboxylic acid groups ensure, for pH ≥ 8, the water solubility of DHLA-capped gold (Au@DHLA) nanoparticles, prepared by the Brust protocol, and the stability of the resulting colloid by electrostatic repulsions. Moreover almost all DHLA, adsorbed onto gold, adopts a conformation allowing their immobilization by both sulfur ends. It is proved by sulfur K-edge X-ray absorption near edge structure spectroscopy, which appears as an appropriate tool for determining the chemical form of sulfur atoms present in the organic monolayer. Such a grafting renders the DHLA monolayers more resistant to displacement by dithiothreitol than mercaptoundecanoic acid monolayers. The presence of DHLA on gold particles allows their functionalization by the electroluminescent luminol through amine coupling reactions assisted by 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride and N-hydroxysuccinimide. As a luminol-functionalized particle is nine times as bright as a single luminol molecule, the use of the particles as a biological probe with a lower threshold of detection is envisaged.

Published
2005

Catalog

Books, media, physical & digital resources
See catalog results