Search

To date, the search for radio technosignatures has focused on sky location as a primary discriminant between technosignature candidates and anthropogenic radio frequency interference (RFI). In this work, we investigate the possibility of searching for technosignatures by identifying the presence and nature of intensity scintillations arising from the turbulent, ionized plasma of the interstellar medium. Past works have detailed how interstellar scattering can both enhance and diminish the detectability of narrowband radio signals. We use the NE2001 Galactic free electron density model to estimate scintillation timescales to which narrowband signal searches would be sensitive, and discuss ways in which we might practically detect strong intensity scintillations in detected signals. We further analyze the RFI environment of the Robert C. Byrd Green Bank Telescope with the proposed methodology and comment on the feasibility of using scintillation as a filter for technosignature candidates.

The Breakthrough Listen search for intelligent life is, to date, the most extensive technosignature search of nearby celestial objects. We present a radio technosignature search of the centers of 97 nearby galaxies, observed by Breakthrough Listen at the Robert C. Byrd Green Bank Telescope. We performed a narrowband Doppler drift search using the turboSETI pipeline with a minimum signal-to-noise parameter threshold of 10, across a drift rate range of ±4 Hz s ^−1 , with a spectral resolution of 3 Hz and a time resolution of ∼18.25 s. We removed radio frequency interference (RFI) by using an on-source/off-source cadence pattern of six observations and discarding signals with Doppler drift rates of 0. We assess factors affecting the sensitivity of the Breakthrough Listen data reduction and search pipeline using signal injection and recovery techniques and apply new methods for the investigation of the RFI environment. We present results in four frequency bands covering 1–11 GHz, and place constraints on the presence of transmitters with equivalent isotropic radiated power on the order of 10 ^26 W, corresponding to the theoretical power consumption of Kardashev Type II civilizations.

Although tuberculosis (TB) is usually curable with antibiotics, poor adherence to medication can lead to increased transmission, drug resistance, and death. Prior research has shown several factors to be associated with poor adherence, but this problem remains a substantial barrier to global TB control. We studied patients in a high-incidence district of Lima, Peru to identify factors associated with premature termination of treatment (treatment default).We conducted a prospective cohort study of adult smear-positive TB patients enrolled between January 2010 and December 2011 with no history of TB disease. Descriptive statistics and multivariable logistic regression analyses were performed to determine risk factors associated with treatment default.Of the 1233 patients studied, 127 (10%) defaulted from treatment. Patients who defaulted were more likely to have used illegal drugs (OR = 4.78, 95% CI: 3.05-7.49), have multidrug-resistant TB (OR = 3.04, 95% CI: 1.58-5.85), not have been tested for HIV (OR = 2.30, 95% CI: 1.50-3.54), drink alcohol at least weekly (OR = 2.22, 95% CI: 1.40-3.52), be underweight (OR = 2.08, 95% CI: 1.21-3.56), or not have completed secondary education (OR = 1.55, 95% CI: 1.03-2.33).Our study identified several factors associated with defaulting from treatment, suggesting a complex set of causes that might lead to default. Addressing these factors individually would be difficult, but they might help to identify certain high-risk patients for supplemental intervention prior to treatment interruption. Treatment adherence remains a barrier to successful TB care and reducing the frequency of default is important for both the patients' health and the health of the community.