Search

Your search keyword '"Brenin, David"' showing total 229 results
Start Over Author "Brenin, David"
229 results on '"Brenin, David"'

1. Use of Mental Health Apps by Patients With Breast Cancer in the United States: Pilot Pre-Post Study

Author

Chow, Philip I, Showalter, Shayna L, Gerber, Matthew, Kennedy, Erin M, Brenin, David, Mohr, David C, Lattie, Emily G, Gupta, Alisha, Ocker, Gabrielle, and Cohn, Wendy F

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

BackgroundNearly half of the patients with breast cancer experience clinically significant mental distress within the first year of receiving their cancer diagnosis. There is an urgent need to identify scalable and cost-efficient ways of delivering empirically supported mental health interventions to patients with breast cancer. ObjectiveThe aim of this study was to evaluate the feasibility of in-clinic recruitment for a mobile phone app study and to evaluate the usability and preliminary impact of a suite of mental health apps (IntelliCare) with phone coaching on psychosocial distress symptoms in patients recently diagnosed with breast cancer. MethodsThis pilot study adopted a within-subject, 7-week pre-post study design. A total of 40 patients with breast cancer were recruited at a US National Cancer Institute–designated clinical cancer center. Self-reported distress (Patient Health Questionnaire-4) and mood symptoms (Patient-Reported Outcomes Measurement Information System depression and anxiety scales) were assessed at baseline and postintervention. App usability was assessed at postintervention. ResultsThe minimum recruitment threshold was met. There was a significant decrease in general distress symptoms, as well as symptoms of depression and anxiety, from baseline to postintervention. Overall, participants reported high levels of ease of app use and learning. Scores for app usefulness and satisfaction were reinforced by some qualitative feedback suggesting that tailoring the apps more for patients with breast cancer could enhance engagement. ConclusionsThere is a dire need for scalable, supportive interventions in cancer. The results from this study inform how scalable mobile phone–delivered programs with additional phone support can be used to support patients with breast cancer. International Registered Report Identifier (IRRID)RR2-10.2196/11452

Published
2020
Full Text
View/download PDF

4. Pain Control in Breast Surgery: Survey of Current Practice and Recommendations for Optimizing Management—American Society of Breast Surgeons Opioid/Pain Control Workgroup

Author

Rao, Roshni, Jackson, Rubie Sue, Rosen, Barry, Brenin, David, Cornett, Wendy, Fayanju, Oluwadamilola M, Chen, Steven L, Golesorkhi, Negar, Ludwig, Kandice, Ma, Ayemoethu, Mautner, Starr Koslow, Sowden, Michelle, Wilke, Lee, Wexelman, Barbara, Blair, Sarah, Gary, Monique, Grobmyer, Stephen, Hwang, E Shelley, James, Ted, Kapoor, Nimmi S, Lewis, Jaime, Lizarraga, Ingrid, Miller, Megan, Neuman, Heather, Showalter, Shayna, Smith, Linda, and Froman, Joshua

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Clinical Research, Pain Research, Patient Safety, Chronic Pain, Neurosciences, Cancer, Breast Cancer, Good Health and Well Being, Analgesics, Opioid, Breast Neoplasms, Female, Humans, Mastectomy, Narcotics, Nerve Block, Pain Management, Pain Measurement, Pain, Postoperative, Practice Patterns, Physicians', Societies, Medical, Surgeons, Surveys and Questionnaires, United States, American Society of Breast Surgeons: Patient Safety & Quality Committee, Research Committee, Oncology and Carcinogenesis, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract

IntroductionThe opioid epidemic in the United States is a public health crisis. Breast surgeons are obligated to provide good pain control for their patients after surgery but also must minimize administration of narcotics to prevent a surgical episode of care from becoming a patient's gateway into opioid dependence.MethodsA survey to ascertain pain management practice patterns after breast surgery was performed. A review of currently available literature that was specific to breast surgery was performed to create recommendations regarding pain management strategies.ResultsA total of 609 surgeons completed the survey and demonstrated significant variations in pain management practices, specifically within regards to utilization of regional anesthesia (e.g., nerve blocks), and quantity of prescribed narcotics. There is excellent data to guide the use of local and regional anesthesia. There are, however, fewer studies to guide narcotic recommendations; thus, these recommendations were guided by prevailing practice patterns.ConclusionsPain management practices after breast surgery have significant variation and represent an opportunity to improve patient safety and quality of care. Multimodality approaches in conjunction with standardized quantities of narcotics are recommended.

Published
2020

8. Novel Form of Breast Intraoperative Radiation Therapy with CT-Guided High-Dose-Rate Brachytherapy: Interim Results of a Prospective Phase-II Clinical Trial

Author

Turkheimer, Lena M, primary, Petroni, Gina R, additional, Berger, Adam C, additional, Schroen, Anneke T, additional, Brenin, David R, additional, Lazar, Melissa, additional, Libby, Bruce, additional, Janowski, Einsley M, additional, Showalter, Timothy N, additional, and Showalter, Shayna L, additional

Published
2023
Full Text
View/download PDF

22. Mastectomy

Author

Brenin, David R., Kinne, David W., Markman, Maurie, editor, and Torosian, Michael H., editor

Published
2002
Full Text
View/download PDF

23. Maintenance of Certification: What Everyone Needs to Know

Author

Callender, Glenda G., Kaplan, Brian J., White, Richard L., Brenin, David R., Chagpar, Anees B., Dalal, Kimberly M., Howard-McNatt, Marissa, Howe, James, Kim, Joseph, Kurtzman, Scott H., Mansour, John C., Mittendorf, Elizabeth A., Stewart, IV, John H., Temple, Larissa K. F., Stella, Patti, Cummings, Charmaine, Wong, Sandra L., and Klimberg, V. Suzanne

Published
2015
Full Text
View/download PDF

31. Contributors

Author

Atkins, Kristen A., primary, Barry, Catherine, additional, Berry, Gerald J., additional, Brenin, David R., additional, Chen, Yunn-Yi, additional, Hazard, Florette K. Gray, additional, Jensen, Kristin C., additional, Kempson, Richard L., additional, Kitayama, Jonathan M., additional, Kong, Christina S., additional, Longacre, Teri A., additional, Ly, Amy, additional, McKenney, Jesse K., additional, Nicholson, Brandi Tamara, additional, Patterson, James W., additional, Peng, Yan, additional, Rogers, William M., additional, Schroen, Anneke T., additional, and van de Rijn, Matt, additional

Published
2013
Full Text
View/download PDF

42. Pluripotent embryonic stem cells from the rat are capable of producing chimeras

Author

Iannaccone, Philip M., Taborn, Greg U., Garton, Ray L., Caplice, Matthew D., and Brenin, David R.

Subjects
Mosaicism -- Physiological aspects, Stem cells -- Research, Biological sciences
Abstract

Rat embryonic stem cells (RESC-01) injected in rat blastocysts generate chimeras. Primary rat embryonic fibroblasts are the best source for the development of RESC-01 cells which are alkaline phosphatase positive and SSEA-1 and show increased differentiation in vitro. RESC-01 cells develop cystic embryoid bodies which exhibit rhythmic compression.

Published
1994

49. Anti-Yo Mediated Paraneoplastic Cerebellar Degeneration Associated with Pseudobulbar Affect in a Patient with Breast Cancer

Author

Martin, Allison N., Dillon, Patrick M., Jones, David E., Brenin, David R., and Lapides, David A.

Subjects
Article Subject
Abstract

Paraneoplastic cerebellar degeneration (PCD) is a rare anti-Yo mediated paraneoplastic syndromes rarely that is infrequently associated with breast cancer. We present a case of a 52-year-old female presenting with diplopia, gait instability, dysarthria, dysphagia, nystagmus, and, most notably, new onset paroxysmal episodes of uncontrollable crying concerning for pseudobulbar affect (PBA). Serologic testing showed anti-Yo antibodies. The patient was found to have stage IIIA breast cancer as the inciting cause of the paraneoplastic syndrome. The patient was treated with neoadjuvant chemotherapy, modified radical mastectomy, adjuvant Herceptin, and pertuzumab. She was given IVIG for paraneoplastic syndrome, antidepressants, and dextromethorphan-quinidine (Nuedexta), the first FDA-approved therapy for PBA. With multimodality therapy, she demonstrated significant improvement in neurologic and mood symptoms associated with PCD and PBA.

Published
2017
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results