15 results on '"Brendan Shi"'
Search Results
2. Renal disease is a risk factor for complications and mortality after open reduction internal fixation of proximal humerus fractures
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Seth Ahlquist, MD, Peter P. Hsiue, MD, Clark J. Chen, MD, Brendan Shi, MD, Alexander Upfill-Brown, MD, Ben V. Kelley, MD, Peyman Benharash, MD, Christos Photopoulos, MD, and Alexandra I. Stavrakis, MD
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Proximal humerus fracture ,Open reduction internal fixation ,Chronic renal disease ,End-stage renal disease ,Dialysis ,Readmission ,Orthopedic surgery ,RD701-811 ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Background: Renal osteodystrophy predisposes renal disease patients to fracture. Proximal humerus fractures (PHFs) frequently undergo open reduction internal fixation (ORIF); however, the effect of renal disease on outcomes is unknown. Methods: A retrospective review of the Nationwide Readmissions Database used International Classification of Diseases, 9th Revision, codes to identify patients who underwent ORIF for closed PHF from 2010 to 2014 with no renal disease, predialysis chronic renal disease (CRD), and end-stage renal disease (ESRD). Results: A total of 85,433 patients were identified, including 5498 (6.4%) CRD and 636 (0.7%) ESRD. CRD and ESRD patients had increased age, comorbidities, and rates of Medicare insurance. After adjusting for differences, CRD and ESRD patients were at increased risk of any complication (odds ratio [OR] 2.48, 1.66), blood transfusion (OR 1.85, 3.31), respiratory complications (OR 1.14, 1.59), acute renal failure (OR 4.80, 1.67), systemic infection (OR 2.00, 3.14), surgical site infection (OR 1.52, 3.87), longer length of stay (7.1 and 12.9 days vs. 5.9 days), and higher cost ($21,669 and $35,413 vs. $20,394) during index hospitalization, as well as surgical site infection (OR 1.43, 3.03) and readmission (OR 1.61, 3.69) within 90 days of discharge, respectively, compared with no renal disease patients. During index hospitalization, CRD patients also had increased risk for periprosthetic fracture (OR 4.97) and cardiac complications (OR 1.47), whereas ESRD patients had increased risk of mortality (OR 5.79), wound complication (2.67), and deep vein thrombosis (OR 16.70). Conclusion: These findings suggest renal patients are at increased risk for complications after PHF ORIF, highlighting the importance of close perioperative monitoring and appropriate patient selection in this population, including strong consideration of nonoperative management.
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- 2022
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3. Epidemiology of Revision Total Knee Arthroplasty in the United States, 2012 to 2019
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Alexander Upfill-Brown, MD, MSc, Peter P. Hsiue, MD, Troy Sekimura, MD, Brendan Shi, MD, Seth A. Ahlquist, MD, Jay N. Patel, DO, Micah Adamson, MD, and Alexandra I. Stavrakis, MD
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Revision total knee arthroplasty ,Clinical epidemiology ,National trends ,Healthcare resource utilization ,Orthopedic surgery ,RD701-811 - Abstract
Background: As primary total knee arthroplasty volume continues to increase, so will the number of revision total knee arthroplasty (rTKA) procedures. The purpose of this study is to provide an updated perspective on the incidence, indications, and financial burden of rTKA in the United States. Material and methods: This was a retrospective epidemiologic analysis using the National Inpatient Sample. International Classification of Diseases ninth and tenth revision codes were used to identify patients who underwent rTKA and create cohorts based on rTKA indications from 2012 to 2019. National and regional trends for length of stay, cost, and discharge location were evaluated. Results: A total of 505,160 rTKA procedures were identified. The annual number of rTKA procedures increased by 29.6% over the study period (56,490 to 73,205). The top 3 indications for rTKA were aseptic loosening (23.1%), periprosthetic joint infection (PJI) (20.4%), and instability (11.0%). Over the study period, the proportion of patients discharged to skilled nursing facility decreased from 31.7% to 24.1% (P < .001). Hospital length of stay decreased from 4.0 days in 2012 to 3.8 days in 2019 (P < .001). Hospital costs increased by $1300 from $25,730 to $27,077 (P < .001). The proportion of rTKA cases performed at urban academic centers increased (52.1% to 74.3%, P < .001) while that at urban nonacademic centers decreased (39.0% to 19.2%, P < .001). Conclusion: The top 3 indications for rTKA were aseptic loosening, PJI, and instability, with PJI becoming the most common indication in 2019. These cases are increasingly being performed at urban academic centers and away from urban nonacademic centers. Level of Evidence: 3 (Retrospective cohort study).
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- 2022
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4. Meniscus Repair in Pediatric Athletes
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Brendan, Shi, Zachary, Stinson, Marie Lyne, Nault, Jennifer, Brey, and Jennifer, Beck
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Adult ,Arthroscopy ,Biological Products ,Athletes ,Humans ,Meniscus ,Physical Therapy, Sports Therapy and Rehabilitation ,Orthopedics and Sports Medicine ,Child ,Menisci, Tibial ,Tibial Meniscus Injuries - Abstract
Meniscus tears are common in the pediatric population, typically occur after noncontact injuries, and can be diagnosed clinically with MRI confirmation. Surgery should be offered to patients with loss of range of motion, persistent symptoms, or displaced/complex tears. Given poor long-term outcomes reported after meniscectomy, repair should be attempted when possible as pediatric menisci are well vascularized and have better outcomes after repair than their adult counterparts. The location of the tear is an important determining factor when deciding on the type of repair to use. Pediatric meniscus repair techniques will be discussed noting differences between pediatric and adult procedures. Further studies are needed to explore the role of biologics and define postoperative protocols.
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- 2022
5. Lower Risk of Revision Surgery After Arthroscopic Versus Open Irrigation and Débridement for Shoulder Septic Arthritis
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Alexander Upfill-Brown, Brendan Shi, Matthew Carter, Carlos Maturana, Chistopher Hart, Akash A. Shah, Dane Brodke, Peter Hsiue, Christos Photopoulos, Christopher Lee, and Alexandra Stavrakis
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Reoperation ,Shoulder ,Arthritis, Infectious ,Arthroscopy ,Debridement ,Humans ,Orthopedics and Sports Medicine ,Surgery ,Retrospective Studies - Abstract
In the treatment of native shoulder septic arthritis, the optimal irrigation and débridement modality-arthroscopic versus open-is a matter of controversy. We aim to compare revision-free survival (RFS), complications, and resource utilization between these approaches.The National Readmission Database was queried from 2016 to 2019 to identify patients using International Classification of Diseases, 10th revision, diagnostic and procedure codes. Days to revision irrigation and débridement (ID) were calculated for patients during index admission or subsequent readmissions. Multivariate regression was used for healthcare utilization analysis. Survival analysis was done using Kaplan-Meier analysis and Cox proportional hazard regression.A total of 4,113 patients with native shoulder septic arthritis undergoing ID were identified, 2,775 arthroscopic (67.5%) and 1,338 open (32.5%). The median follow-up was 170 days (interquartile range 79 to 265). A total of 341 patients (8.3%) underwent revision ID at a median of 9 days. On multivariate analysis, arthroscopic ID was associated with a reduction in hospital costs of $4,154 ( P0.001) and length of stay of 0.78 days ( P = 0.030). Arthroscopic ID was associated with reduced blood transfusions (odds ratio 0.69, P = 0.001) and wound complications (odds ratio 0.30, P0.001). RFS was 96.4%, 94.9%, 93.3%, and 92.6% for arthroscopic ID and 94.1%, 92.6%, 90.4%, and 89.0% for open ID at 10, 30, 90 and 180 days, respectively ( P = 0.00043). On multivariate Cox modeling, arthroscopic ID was associated with improved survival (hazard ratio 0.67, P = 0.00035). On stratified analysis, arthroscopic ID was associated with improved RFS in patients aged 65 years or older ( P0.001), but RFS was similar in those younger than 65 years ( P = 0.17).Risk of revision ID was markedly lower after arthroscopic ID compared with open, although the protective benefit was limited to patients aged 65 years or older. Arthroscopy was also associated with decreased costs, length of stay, and complications. Although surgeons must consider specific patient factors, our results suggest that arthroscopic ID is superior to open ID.III.
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- 2022
6. Reduced Costs, Complications, and Length of Stay After Arthroscopic Versus Open Irrigation and Débridement for Knee Septic Arthritis
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Alexander Upfill-Brown, Brendan Shi, Matthew Carter, Carlos Maturana, Dane Brodke, Akash A. Shah, Peter Hsiue, Christos Photopoulos, Christopher Lee, and Alexandra Stavrakis
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Arthritis, Infectious ,Debridement ,Humans ,Orthopedics and Sports Medicine ,Surgery ,Length of Stay ,Therapeutic Irrigation ,Retrospective Studies - Abstract
In the treatment of native knee bacterial septic arthritis, the optimal irrigation and débridement modality-arthroscopic versus open-is a matter of controversy. We aim to compare revision-free survival, complications, and resource utilization between these approaches.The National Readmission Database was queried from 2016 to 2019 to identify patients using International Classification of Diseases, 10th revision, diagnostic and procedure codes. Days to revision irrigation and débridement (ID), if any, were calculated for patients during index admission or subsequent readmissions. Multivariate regression was used for healthcare utilization analysis. Survival analysis was done using Kaplan-Meier analysis and Cox proportional hazard regression.A total of 14,365 patients with native knee septic arthritis undergoing ID were identified, 8,063 arthroscopic (56.1%) and 6,302 open (43.9%). The mean follow-up was 148 days (interquartile range 53 to 259). A total of 2,156 patients (15.0%) underwent revision ID. On multivariate analysis, arthroscopic ID was associated with a reduction in hospital costs of $5,674 and length of stay of 1.46 days (P0.001 for both). Arthroscopic ID was associated with lower overall complications (odds ratio [OR] 0.63, P0.001), need for blood transfusion (OR 0.58, P0.001), and wound complications (OR 0.32, P0.001). Revision-free survival after index ID was 95.3% at 3 days, 91.0% at 10 days, 88.3% at 30 days, 86.0% at 90 days, and 84.5% at 180 days. No statistically significant difference was observed between surgical approaches on Cox modeling.Risk of revision ID did not differ between arthroscopic and open ID; however, arthroscopy was associated with decreased costs, length of stay, and complications. Additional study is necessary to confirm these findings and characterize which patients require an open ID.III.
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- 2022
7. Higher rates of readmission following acute total hip arthroplasty versus open reduction internal fixation for elderly acetabular fractures, a national study from 2010 to 2019
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Alexander Upfill-Brown, Brendan Shi, Carlos Maturana, Dane Brodke, Akash A Shah, Benjamin V Kelley, Erik N Mayer, Sai K Devana, and Christopher Lee
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Orthopedics and Sports Medicine ,Surgery ,General Medicine - Published
- 2023
8. Postoperative Care/Rehabilitation
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Brendan Shi and Christopher Lee
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- 2023
9. List of Contributors
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J.D. Adams, Jesse Jay Caballero, James Gainer, Brandi Hartley, Yohan Jang, Daniel Oscar Johansen, Adam D. Kessler, Christopher Lee, Travis Parkulo, Cassandra Anne Ricketts, John T. Riehl, Adam A. Sassoon, Abhijit Seetharam, David Seligson, Brendan Shi, Jan Szatkowski, and James Widmaier
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- 2023
10. 138. Racial disparities in utilization of and short-term outcomes following cervical disc replacement vs anterior cervical discectomy and fusion
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Alexander Upfill-Brown, Brendan Shi, Durga Ghosh, Jeremy Policht, Beau Sperry, Akash A. Shah, William Sheppard, Elizabeth L. Lord, A. Nick Shamie, and Don Y. Park
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Surgery ,Orthopedics and Sports Medicine ,Neurology (clinical) - Published
- 2022
11. Paper 23: The Impact of Graft Choice on Return to Sport Testing After Adolescent ACL Reconstruction
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Kevin Chen, Abbie Bennett, Jennifer Beck, and Brendan Shi
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Orthopedics and Sports Medicine - Abstract
Objectives: The number of anterior cruciate ligament (ACL) injuries and reconstructions observed in the adolescent population continues to rise. While the use of quadriceps tendon autograft has increased in popularity in this population, there remains no consensus on the ideal graft for pediatric ACL reconstruction. The objective of this study was to compare three commonly used ACL graft types with respect to i) performance on return to sport assessments and ii) timing to clearance for return to sports in an adolescent population. Methods: All patients, less than or equal to 19 years of age, who underwent reconstruction for ACL tears between 2016 and 2020 at a large, urban, academic institution were identified. Graft choice was made in a shared decision-making model with patient, parents, and surgeon. Patient demographics, laterality, graft type, time from surgery to clearance, number of physical therapy (PT) visits, and presence of concomitant meniscus injuries were collected from the electronic medical record. At a minimum of 6 months postoperatively, patients completed a formal return to sport test (RTS) including isometric strength assessments, Y- balance testing, and hop testing. Treatment cohorts based on graft type were compared with respect to RTS performance and timing to clearance. Associations between patient demographics and return to sport timing and performance were also assessed. Clearance for return to sport was determined by the treating surgeon with limb symmetry index of 90% on RTS as the goal for clearance. Results: A total of 110 adolescents, 44 female (40%), with a mean age of 16.3 years (SD, 1.7; range, 10-19) met our inclusion criteria (Table 1). Average time to first RTS assessment was 280 days (9.3 months) and average time to clearance was 371 days (12.2 months) after surgery. ACL grafts included 58 (52.7%) hamstring autografts, 26 (23.6%) bone-patellar tendon-bone (BPTB) autografts, 21 (19.1%) bone quadriceps (BQT) autografts, and 5 (4.6%) iliotibial band (ITB) autografts. ITB patients were younger on average (12.5 years old) than those receiving hamstring, BPTB or BQT grafts. There were no significant differences between groups with respect to laterality, number of physical therapy visits, or rate of concurrent meniscus surgery. Patients receiving BQT grafts were more likely to be cleared within 1 year of surgery compared to hamstring graft patients (82.4% vs. 39.6%, p=0.002) and had similar rates of clearance within 1 year compared to BPTB patients (82.4% vs. 65.2%, p=0.230). Patients with BQT and BPTB grafts both demonstrated significantly better hamstring strength symmetry compared to hamstring graft patients (5.8% strength deficit compared to healthy side vs. 1.3% vs. 29.3%, pConclusions: In this study of 110 adolescent ACL reconstruction patients who underwent return to sport evaluations, we found no significant difference between BPTB and BQT autografts with respect to RTS performance and time to clearance. Hamstring autograft was associated with significantly worse hamstring strength asymmetry and significantly lower rates of clearance within 1 year. Concurrent meniscus surgery, age, gender, and number of PT sessions completed prior to RTS evaluation were not significantly associated with timing of clearance or performance on the RTS assessment. [Table: see text][Table: see text]
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- 2022
12. Poster 120: The Impact of the COVID-19 Pandemic on Injury Onset and Timing in Division 1 NCAA Athletes
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Shannon Wu, Alexander Upfill-Brown, Amador Bugarin, Kristofer Jones, Thomas Kremen, and Brendan Shi
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Orthopedics and Sports Medicine - Abstract
Objectives: The spread of the coronavirus disease 2019 (COVID-19) in February and March of 2020 led to the delay or cancellation of major sporting leagues and events across the globe. Collegiate athletic competitions were postponed until the end of the 2020 calendar year and organized collegiate athletic practices and training camps throughout 2020 were either cancelled or significantly reduced in frequency. The impact of the COVID-19 pandemic on injury epidemiology in collegiate athletics has not yet been investigated. We aim to describe the types of athletic injuries sustained by high level collegiate athletes before and after the COVID-19 pandemic. Methods: The Pacific 12 (Pac-12) Health Analytics Program contains all injuries sustained by intercollegiate athletes in the Pac-12 conference. This database was queried for injuries that occurred across all sports from January 2019 to June 2021. For all sports, timing of injury onset (acute versus overuse), severity of injury, rate of procedural intervention, injury mechanism (contact versus non-contact), and likelihood of injury during the 4th quarter of competition (final 25% of competition) was compared between the season immediately preceding the COVID-19 pandemic and the season immediately after. In this database, injury timing is defined as overuse if symptom onset occurred more than 24 hours after the precipitating incident. Results were stratified by upper and lower extremity as well as sport. Sub group analyses were also performed on knee and shoulder injuries among athletes competing in sports with historically high rates of knee and shoulder injuries. Multivariate analysis including gender was performed. Results: A total of 12,319 sport-related injuries across 23 sports were identified. The overall proportion of injuries sustained during the 4th quarter of competition was higher in the post-pandemic season (28.5% vs. 25.9%, p=0.015) and the overall proportion of non-contact injury was higher in the post-pandemic season (46.1% vs. 39.8%, pConclusions: Compared with the season immediately preceding the COVID-19 pandemic, athletes competing in the post-pandemic season were at higher risk of non-contact injury and injury near the end of a competition. There was a higher risk of overuse knee injuries and non-contact knee and shoulder injuries in the post-pandemic season. These findings are the first to describe the effect of a global pandemic on an athlete’s injury risk profile upon return to sport and may be used to guide decisions regarding athlete workload and training. [Table: see text][Table: see text][Table: see text]
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- 2022
13. To improve existing marsh bird survey protocols, we need to evaluate closure assumptions
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Auriel M. V. Fournier, Therin M. Bradshaw, Heath M. Hagy, and Brendan Shirkey
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call‐broadcast surveys ,closure ,detection ,marsh birds ,migration ,General. Including nature conservation, geographical distribution ,QH1-199.5 - Abstract
Abstract Our collective understanding of secretive marsh birds has increased in the past decades due to the development and implementation of the North American Standardized Marsh Bird Monitoring Protocol (hereafter, Protocol). The Protocol proposes call broadcast surveys to increase vocalization and detection rates within 3 standardized survey periods aimed at surveying peak breeding activity for a suite of secretive marsh birds. We noted a trend in the literature linking occupancy modeling with the survey design from the Protocol, despite some evidence that vocalizations decline across survey periods, which could indicate lack of population closure. An underlying assumption of occupancy modeling is closure, and the Protocol was designed to focus on only birds which will remain in an area throughout the breeding season and not migrants that may only be present in the first survey period. Including migrating marsh birds, especially if a large percentage of marsh bird detections are migrants, can bias occupancy estimates and lead to erroneous density and population size estimates that may affect conclusions about habitat resource and bird associations. We urge researchers and managers to carefully consider the analytical and field techniques when designing studies for marsh birds and to not simply pair the biweekly survey design within the Protocol with occupancy modeling and ignore closure assumptions, turnover rates, and potential differences in resource use by migrating and breeding marsh birds. Specifically, we suggest that researchers consider short survey interval times (e.g., ~2 days rather than 2 weeks) or continuous call monitoring using automated recorded devices deployed for 1–2 weeks per survey location when using occupancy analysis on secretive marsh birds. We also call for future study of turnover rates, stopover duration, and vocalization rates during migration and breeding periods to better inform study designs and increase the appropriateness of statistical analysis.
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- 2023
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14. Population genetics and geographic origins of mallards harvested in northwestern Ohio.
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Michael L Schummer, John Simpson, Brendan Shirkey, Samuel R Kucia, Philip Lavretsky, and Douglas C Tozer
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Medicine ,Science - Abstract
The genetic composition of mallards in eastern North America has been changed by release of domestically-raised, game-farm mallards to supplement wild populations for hunting. We sampled 296 hatch-year mallards harvested in northwestern Ohio, October-December 2019. The aim was to determine their genetic ancestry and geographic origin to understand the geographic extent of game-farm mallard introgression into wild populations in more westward regions of North America. We used molecular analysis to detect that 35% of samples were pure wild mallard, 12% were early generation hybrids between wild and game-farm mallards (i.e., F1-F3), and the remaining 53% of samples were assigned as part of a hybrid swarm. Percentage of individuals in our study with some form of hybridization with game-farm mallard (65%) was greater than previously detected farther south in the mid-continent (~4%), but less than the Atlantic coast of North America (~ 92%). Stable isotope analysis using δ2Hf suggested that pure wild mallards originated from areas farther north and west than hybrid mallards. More specifically, 17% of all Ohio samples had δ2Hf consistent with more western origins in the prairies, parkland, or boreal regions of the mid-continent of North America, with 55%, 35%, and 10% of these being genetically wild, hybrid swarm, and F3, respectively. We conclude that continued game-farm introgression into wild mallards is not isolated to the eastern population of mallards in North America, and may be increasing and more widespread than previously detected. Mallards in our study had greater incidence of game-farm hybridization than other locales in the mid-continent but less than eastern North American regions suggesting further need to understand game-farm mallard genetic variation and movement across the continent.
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- 2023
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15. Purely antiferromagnetic magnetoelectric random access memory
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Tobias Kosub, Martin Kopte, Ruben Hühne, Patrick Appel, Brendan Shields, Patrick Maletinsky, René Hübner, Maciej Oskar Liedke, Jürgen Fassbender, Oliver G. Schmidt, and Denys Makarov
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Science - Abstract
Magnetoelectric coupling allows switching of magnetic states via gate voltage pulses. Here the authors propose and demonstrate a purely antiferromagnetic magnetoelectric random access memory based on Cr2O3, reporting 50-fold reduction of writing threshold compared to ferromagnetic counterparts.
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- 2017
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