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A recent study conducted by the Leibniz Institute for Prevention Research and Epidemiology in Bremen, Germany, aimed to identify biomarkers associated with the intake of sweet and fatty snacks in European children. The research found 66 metabolites that were statistically significant for various snack categories, with three biomarkers of chocolate intake being externally replicated. However, further validation of these potential biomarkers in children is needed. This study highlights the importance of using metabolite biomarkers to objectively assess children's food intake and establish diet-disease relationships. [Extracted from the article]

A recent report from the School of Science in Bremen, Germany discusses the chemical and metabolic reactivity of polyphenols in food processing and metabolism. The researchers highlight the diverse chemical transformations that occur in black tea and coffee chemistry, resulting in a wide range of polyphenolic compounds. They also emphasize the role of gut microbiota in converting dietary polyphenols into novel structures. The study utilizes advanced analytical techniques, such as mass spectrometry, to unravel the complexity of polyphenols. The research concludes by discussing the nonselective protein binding and loss of enzymatic function associated with polyphenols. [Extracted from the article]

The article from the University of Bremen presents new research on managing recurrent urinary tract infections (rUTI). Topics include the effectiveness of urine culture and ultrasonography in diagnosing rUTI, the comparative benefits and risks of antibiotic versus non-antibiotic preventive measures, and the impact of increased fluid intake and hygienic practices on infection rates.

A recent study conducted at the University of Bremen in Germany explores the potential use of zeolites as carrier materials for the controlled release of the anticancer drug 5-fluorouracil (5-FU). The researchers used density functional theory calculations and ab initio molecular dynamics simulations to investigate the interaction between 5-FU and faujasite-type zeolites with different Si/Al ratios. They found that the presence of multiple protons in the zeolite framework enhances the adsorption energy of 5-FU, and that the high affinity of water to the framework protons can trigger the release of 5-FU. This research provides valuable insights into the storage and release mechanisms of 5-FU in zeolites, which could have implications for drug delivery applications. [Extracted from the article]

A recent study conducted by researchers at the School of Sciences in Bremen, Germany, has developed a five-enzyme cascade for the synthesis of a cyclic dinucleotide called 2'3'-cGAMP. This cascade allows for the multi-step synthesis of pharmaceutically relevant active ingredients in a one-pot reaction without the need for purification of intermediates. The researchers achieved an overall conversion rate of 57% of the substrates into 2'3'-cGAMP. This research has been peer-reviewed and provides valuable insights into the development of multi-enzyme cascades for pharmaceutical synthesis. [Extracted from the article]

A report from the Department of Neurology in Bremen, Germany discusses the use of psychological treatments for MS-related fatigue. The researchers argue that the evidence for energy conservation training is weak and propose a new treatment approach based on the subjective representation of fatigue as an inflammatory state. They suggest a three-step treatment approach involving short-term control of fatigue, extinction to reduce avoidance behavior, and pacing. The researchers hope that this new approach will improve the treatment of fatigue in the future. The research has been peer-reviewed and published in the Journal of the Neurological Sciences. [Extracted from the article]

A recent study conducted by the University of Bremen in Germany examined the factors contributing to regional variations in outpatient antibiotic prescribing. The study found that socioeconomic and healthcare density differences did not fully explain these variations. Instead, factors such as poor coordination between in-patient and ambulatory health services, lack of information on antimicrobial resistance, and regional variations in patient expectations were identified as barriers to rational prescribing behavior. The study suggests that interventions targeting professional development, better collaboration structures, and clearer guidelines could support more appropriate antibiotic prescribing. Additionally, better networking and social support among physicians may help lower prescription rates. [Extracted from the article]

A study conducted at the University of Bremen in Germany has found that alumina ceramic textiles may be an effective alternative to antimicrobial dressings for treating wounds. Antimicrobial dressings can lead to antibiotic-resistant strains and hinder wound healing. The alumina textiles, which have a hierarchical structure and high specific surface area, were found to be highly efficient in capturing bacteria from the wound bed and preventing bacterial infiltration. The study suggests that ceramic textiles could be a promising material for wound dressings. [Extracted from the article]

Researchers from the School of Sciences in Bremen, Germany have synthesized a series of amphiphilic p-sulfonatocalix[4]arenes with varying alkyl chain lengths and studied their ability to activate the uptake of cell-penetrating peptides (CPPs) into cells. The researchers found that these compounds, particularly the dodecyl derivative CX4-C12, were highly effective in delivering CPPs into the cytosol of live cells. Mechanistic studies suggest that these compounds directly translocate CPP-counterion complexes into the cytosol, bypassing the endocytosis pathway. This research provides valuable insights into the development of efficient methods for delivering CPP-conjugated cargo molecules into cells. [Extracted from the article]

Researchers from the University of Bremen in Germany have conducted a study on astrocyte cultures to investigate the release of pyruvate, a compound believed to have neuroprotective functions. The study found that astrocytes establish a transient extracellular steady state concentration of pyruvate, which is influenced by modulation of mitochondrial pyruvate metabolism. The research provides insights into the processes involved in astrocytic pyruvate release and its potential role in neuroprotection. The study was funded by the University of Bremen and has been peer-reviewed. [Extracted from the article]

A recent report from the University of Bremen highlights the emotional and psychological toll that qualitative field-based research on violence, particularly gender-based violence (GBV), can have on researchers. The existing self-care strategies for practitioners in this field often fail to address the unique challenges faced by researchers. The report suggests that collaborative and relational approaches, such as peer-support and fostering "caring communities," are necessary for coping with the emotional and psychological toll of GBV research. These strategies become particularly important in the absence of support and care at the structural and institutional level. The research emphasizes the need for a more holistic and supportive approach to self-care in this field. [Extracted from the article]

A study conducted by the University of Bremen examines the impact of the European Union's Article 17 on copyright content moderation on YouTube in Germany and France. The study measures overblocking due to copyright moderation and changes in the diversity of cultural products on YouTube. The findings reveal significant differences between the two countries in terms of video takedowns related to copyright, as well as a decrease in cultural diversity on YouTube's platform. The research contributes to the field of content moderation and establishes new methodological frameworks for further exploration. [Extracted from the article]

A recent report from researchers at the University of Bremen in Germany discusses the use of numerical simulation to understand mass transport in complex structures. The study focuses on the importance of resolving the complex morphology and considering both convection and diffusion in the simulation. The researchers used computational fluid dynamics (CFD) simulations and experimental measurements to analyze gas flow in open-cell foams. The results showed a good match between the simulations and measurements, demonstrating the effectiveness of both methods for analyzing multi-scale transport. This research has been peer-reviewed and provides valuable insights into mass transport analysis. [Extracted from the article]

A new report from the University of Bremen discusses the implications of including policies on paid family care in the concept of care policy for older people. The report evaluates the relationship between these policies and gender inequality, with most researchers agreeing that policies supporting extra-familial care can reduce gender inequality by promoting women's participation in paid work. However, the role of policies offering pay and social security for family care in promoting gender equality is still debated. The report argues that new policies on paid family care have the potential to reduce gender inequality under specific conditions, and suggests that including these policies in the study of care policy could clarify their contribution to fostering gender equality. [Extracted from the article]

A new report from the University of Bremen in Germany discusses the cultural and institutional contexts of family care and its relationship to care policies, gender, and the family. The report highlights the lack of research on family care in the context of contemporary care policies and presents seven articles that explore theoretical debates and cross-national differences in family care. The research concludes that analyzing the development of family care in its institutional and cultural contexts can enhance our understanding of the changing relationship between family, gender, and care. For more information, readers can refer to the Journal of Family Research. [Extracted from the article]

New research conducted by the University of Bremen explores the intergenerational effects of child maltreatment on adolescents' anxiety and depression in Ethiopia. The study found that child abuse and neglect were prevalent among both adolescents and their parents, with 68% of adolescents and 65% of parents reporting exposure to maltreatment. The research also revealed that adolescents with parents who had a history of child abuse and neglect were more likely to experience maltreatment themselves. The study suggests that intervention plans should consider multiple access points to address the mental health needs of affected youth in Africa. [Extracted from the article]

A recent study conducted by researchers at the University of Bremen in Germany evaluated the psychometric qualities of the German HEXACO-60 personality inventory. The study examined both self-reports and observer-reports to assess the consistency, validity, and measurement invariance of the inventory. The findings showed satisfying internal consistency, rank-order stability, agreement among raters, and consensus among informant-raters. The study concluded that the informant perspective provides valid additional benefits for assessing personality traits within the HEXACO framework. This research has been peer-reviewed and published in the European Journal of Psychological Assessment. [Extracted from the article]

A recent report from Bremen, Germany discusses the treatment of a rare condition called dentinogenic ghost cell tumor (DGCT) in a 12-year-old boy. DGCT is a benign tumor that can cause extensive damage to the jaw and has a tendency to recur. The case involved the tumor infiltrating the temporomandibular joint (TMJ), which posed challenges for surgery and reconstruction. A two-staged reconstructive approach was used, involving the restoration of mandibular anatomy and the use of a customized TMJ prosthesis. The long-term effects on growth and the need for additional interventions will be evaluated in follow-up. This research has been peer-reviewed. [Extracted from the article]

A recent report discusses research findings on breast cancer screening attendance in Spain. Despite organized screening programs, significant attendance inequalities persist among different population groups. The study used a quantitative intersectional perspective to identify intersectional positions at risk of not undergoing breast cancer screening. Decision tree models and ensemble algorithms were applied to identify factors influencing screening attendance, such as regional differences, education, age, and marital status. The study concludes that targeted interventions can be developed to increase attendance among high-risk groups. [Extracted from the article]

Researchers from the University of Bremen in Germany have conducted a study on sustainability-oriented secondary chemistry education in mainland China. The study focused on the cultural aspects of socio-scientific issues, specifically addressing Confucian ecological ethics. A lesson plan was developed and implemented online due to the COVID-19 pandemic, and it included activities to raise students' awareness of environmentally friendly attitudes and behaviors. The research concluded that incorporating Confucian ecological ethics can contribute to chemistry education for sustainable development in Confucian societies. This study provides valuable insights into the intersection of cultural values and science education in China. [Extracted from the article]

A recent study conducted at the University of Bremen in Germany has provided new insights into chemicals and chemistry. The researchers investigated the reaction between 1,2-bis(2,5-dimethylthiophen-3-yl)ethane-1,2-dione (DTEthane) and metal precursors of group four (M=Ti, Zr, Hf). They found that the resulting complexes had different molecular structures and chiral properties depending on the metal center. Quantum chemical calculations were used to evaluate the trend of dimer formation. The study highlights the importance of coplanarity and conjugation in determining the chiral properties of these complexes. [Extracted from the article]

Bremen, Germany, Europe, Antineoplastic Monoclonal Antibodies, Antineoplastics, Antirheumatics, Biotechnology, CD20 Monoclonal Antibodies, Chemotherapy, Drugs and Therapies, Health and Medicine, Hemic and Lymphatic Diseases and Conditions, Immune System Diseases and Conditions, Immunologic Agents, Immunology, Immunoproliferative Disorders, Lymphoproliferative Disorders, Medical Devices, Monoclonal Antibodies, Pharmaceuticals, Rituximab Therapy, Tyrosine Kinase Inhibitors Keywords: Bremen; Germany; Europe; Antineoplastic Monoclonal Antibodies; Antineoplastics; Antirheumatics; Biotechnology; CD20 Monoclonal Antibodies; Chemotherapy; Drugs and Therapies; Health and Medicine; Hemic and Lymphatic Diseases and Conditions; Immune System Diseases and Conditions; Immunologic Agents; Immunology; Immunoproliferative Disorders; Lymphoproliferative Disorders; Medical Devices; Monoclonal Antibodies; Pharmaceuticals; Rituximab Therapy; Tyrosine Kinase Inhibitors EN Bremen Germany Europe Antineoplastic Monoclonal Antibodies Antineoplastics Antirheumatics Biotechnology CD20 Monoclonal Antibodies Chemotherapy Drugs and Therapies Health and Medicine Hemic and Lymphatic Diseases and Conditions Immune System Diseases and Conditions Immunologic Agents Immunology Immunoproliferative Disorders Lymphoproliferative Disorders Medical Devices Monoclonal Antibodies Pharmaceuticals Rituximab Therapy Tyrosine Kinase Inhibitors 2964 2964 1 10/30/23 20231031 NES 231031 2023 NOV 3 (NewsRx) -- By a News Reporter-Staff News Editor at Immunotherapy Weekly -- A new study on Immune System Diseases and Conditions - Lymphoproliferative Disorders is now available. [Extracted from the article]

Researchers at the University of Bremen have published a report on violent behavior, specifically focusing on the concept of "culture of honor." The researchers explain that a culture of honor involves individuals deterring others through signaling their commitment to violent retaliation. They argue that both individual and system-level honor contribute to an increase in violence, but as system-level honor becomes more prevalent, the impact of individual honor diminishes. The researchers analyzed the effect of culture of honor on school violence among 15-year-old adolescents and found that the deterrent effect must be unrealistically high to generate an equilibrium of average violence. This research has been peer-reviewed and provides insights into the relationship between honor and violence. [Extracted from the article]