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Your search keyword '"Breast neoplasms, male"' showing total 3,170 results
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3,170 results on '"Breast neoplasms, male"'

3. ETHAN - ET for Male BC

Author

Eli Lilly and Company, Translational Breast Cancer Research Consortium (TBCRC), and Jose Pablo Leone, Principal Investigator

Published
2024

17. The Characteristics, Treatment Patterns and Prognosis of Chinese Male Breast Cancer: A Real-world Study

Author

Beijing Medical Award Foundation, The Affiliated Cancer Hospital of Xinjiang Medical University, Hebei Medical University Fourth Hospital, The Third Affiliated Hospital of Kunming Medical University, Sun Yat-sen University, The Affiliated Cancer Hospital of Zhengzhou University, The Third Hospital of Nanchang City, Beijing 302 Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Fujian Provincial Hospital, First Hospital of China Medical University, The Affiliated Hospital of Qingdao University, Guangdong Provincial People's Hospital, First Affiliated Hospital Xi'an Jiaotong University, First People's Hospital of Foshan, Peking University First Hospital, The Affiliated Hospital Of Guizhou Medical University, Guangdong Provincial Hospital of Traditional Chinese Medicine, Jiangmen Central Hospital, The Second Affiliated Hospital, Guangzhou Medical University, The First Affiliated Hospital, Zhejiang University, Peking University Shenzhen Hospital, The Second Affiliated Hospital of Harbin Medical University, Affiliated Sanming First Hospital of Fujian Medical University, Jieyang People's Hospital, National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Shantou Central Hospital, The First Affiliated Hospital with Nanjing Medical University, Lianjiang Pepole's Hospital, Lianjiang, Guangdong Women and Children Hospital, Zhanjiang Central Hospital, Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine, and Ying Lin, MD, PhD

Published
2024

21. Male Breast Cancer: Understanding the Biology for Improved Patient Care

Author

Breast International Group, Swiss Group for Clinical Cancer Research, Cancer Trials Ireland, Borstkanker Onderzoek Groep, Swedish Association of Breast Oncologists, Hellenic Cooperative Oncology Group, Hellenic Oncology Research Group, Latin American Cooperative Oncology Group, and Translational Breast Cancer Research Consortium

Published
2023

29. Probability of a high recurrence score for breast cancer on the Oncotype DX test in males: a case series

Author

Rafael Everton Assunção Ribeiro da Costa, Fergus Tomás Rocha de Oliveira, Cristiane Amaral dos Reis, and Sabas Carlos Vieira

Subjects
Nomograms, Genomics, Medical Records, Breast Neoplasms, Male, Medicine (General), R5-920
Abstract

Abstract Introduction: Male breast cancer (MBC) is a rare disease that accounts for 1% of breast cancers. The Oncotype DX test (a genomic signature that assesses the expression of 21 genes to estimate the recurrence score [RS]) has been widely used in MBC to select patients for adjuvant chemotherapy. Objective: To describe 5 cases of MBC in which a nomogram was used to predict the probability of having a high Oncotype DX score for breast cancer and the need to perform genomic signature. Materials and methods: Case series study in which five patients with MBC treated between 2007 and 2020 at a cancer institution in Teresina (Brazil) were included. A nomogram was performed to evaluate five clinical and pathological variables (age, body size, tumor size, grade, recurrence score status, and histologic type of carcinoma). Case series: The mean age of the patients at diagnosis was 69 years (mean tumor size: 2.6cm). All patients received hormone therapy with tamoxifen, three received chemotherapy, and one received radiation therapy after breast surgery (mastectomy). During a median follow-up period of 88 months, one case had a recurrence (bone metastasis). Based on the nomogram results, two patients had a high probability of a high RS (36% and 45%) and only one patient (case 3) underwent Oncotype DX testing (RS: 20). Conclusions: In the present series of five cases, based on the nomogram results, only two patients (cases 3 and 4) had a high probability of a high Oncotype DX recurrence score; however, due to financial constraints, this test was only performed on one of these two patients. The patient who underwent the test (case 3) did not receive adjuvant chemotherapy and remained alive with bone metastases until the end of the follow-up period. Conversely, the patient who could not undergo the examination (case 4) received adjuvant chemotherapy and was alive without any signs of disease.

Published
2023
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