561 results on '"Brayden, David J."'
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2. Safety of surfactant excipients in oral drug formulations
3. Localised Delivery of Macromolecules to the Large Intestine: Translation to Clinical Trials
4. Buccal delivery of small molecules and biologics: Of mucoadhesive polymers, films, and nanoparticles – An update
5. Best practices in current models mimicking drug permeability in the gastrointestinal tract - An UNGAP review
6. Measuring the oral bioavailability of protein hydrolysates derived from food sources: A critical review of current bioassays
7. Formulation strategies to improve the efficacy of intestinal permeation enhancers,
8. Sodium glycodeoxycholate and sodium deoxycholate as epithelial permeation enhancers: in vitro and ex vivo intestinal and buccal bioassays
9. Comparison of the effects of the intestinal permeation enhancers, SNAC and sodium caprate (C10): Isolated rat intestinal mucosae and sacs
10. A Critical Overview of the Biological Effects of Excipients (Part II): Scientific Considerations and Tools for Oral Product Development
11. Salcaprozate sodium (SNAC) enhances permeability of octreotide across isolated rat and human intestinal epithelial mucosae in Ussing chambers
12. A head-to-head Caco-2 assay comparison of the mechanisms of action of the intestinal permeation enhancers: SNAC and sodium caprate (C10)
13. Reproducible Synthesis of Biocompatible Albumin Nanoparticles Designed for Intra-articular Administration of Celecoxib to Treat Osteoarthritis
14. Labrasol® is an efficacious intestinal permeation enhancer across rat intestine: Ex vivo and in vivo rat studies
15. Effect of Overencapsulation on the Disintegration and Dissolution of Licensed Formulations for Blinding in Randomized Controlled Trials
16. An in Situ Bioadhesive Foam as a Large Intestinal Delivery Platform for Macromolecules to Treat Inflammatory Bowel Disease
17. Erratum to “Sodium glycodeoxycholate and sodium deoxycholate as epithelial permeation enhancers: in vitro and ex vivo intestinal and buccal bioassays” [European Journal of Pharmaceutical Sciences 159 (2021) 105737]
18. Physicochemical, pharmacokinetic and pharmacodynamic analyses of amphiphilic cyclodextrin-based nanoparticles designed to enhance intestinal delivery of insulin
19. TNFα-dependent anhedonia and upregulation of hippocampal serotonin transporter activity in a mouse model of collagen-induced arthritis
20. Sodium caprate enables the blood pressure-lowering effect of Ile-Pro-Pro and Leu-Lys-Pro in spontaneously hypertensive rats by indirectly overcoming PepT1 inhibition
21. Labrasol® and Salts of Medium-Chain Fatty Acids Can Be Combined in Low Concentrations to Increase the Permeability of a Macromolecule Marker Across Isolated Rat Intestinal Mucosae
22. Buccal delivery of small molecules and biologics: of mucoadhesive polymers, films, and nanoparticles
23. A comparison of three Peyer’s patch “M-like” cell culture models: particle uptake, bacterial interaction, and epithelial histology
24. Evaluation of PepT1 transport of food-derived antihypertensive peptides, Ile-Pro-Pro and Leu-Lys-Pro using in vitro, ex vivo and in vivo transport models
25. Nanoparticle passage through porcine jejunal mucus: Microfluidics and rheology
26. Intra-articular delivery of a nanocomplex comprising salmon calcitonin, hyaluronic acid, and chitosan using an equine model of joint inflammation
27. Coated minispheres of salmon calcitonin target rat intestinal regions to achieve systemic bioavailability: Comparison between intestinal instillation and oral gavage
28. Oral delivery strategies for nutraceuticals: Delivery vehicles and absorption enhancers
29. Evolving peptides for oral intake
30. Evaluation of Selenomethionine Entrapped in Nanoparticles for Oral Supplementation Using In Vitro, Ex Vivo and In Vivo Models
31. Stability, toxicity and intestinal permeation enhancement of two food-derived antihypertensive tripeptides, Ile-Pro-Pro and Leu-Lys-Pro
32. High-content analysis for drug delivery and nanoparticle applications
33. Sodium caprate-induced increases in intestinal permeability and epithelial damage are prevented by misoprostol
34. First-in-class thyrotropin-releasing hormone (TRH)-based compound binds to a pharmacologically distinct TRH receptor subtype in human brain and is effective in neurodegenerative models
35. Human: Veterinary Technology Cross Over
36. Investigation of coco-glucoside as a novel intestinal permeation enhancer in rat models
37. A head-to-head multi-parametric high content analysis of a series of medium chain fatty acid intestinal permeation enhancers in Caco-2 cells
38. Progress in the delivery of nanoparticle constructs: towards clinical translation
39. Drug Delivery Systems in Domestic Animal Species
40. The role of citric acid in oral peptide and protein formulations: Relationship between calcium chelation and proteolysis inhibition
41. Effects of surfactant-based permeation enhancers on mannitol permeability, histology, and electrogenic ion transport responses in excised rat colonic mucosae
42. Development of a Non-Aqueous Dispersion to Improve Intestinal Epithelial Flux of Poorly Permeable Macromolecules
43. Characterization of the physicochemical interactions between exenatide and two intestinal permeation enhancers: Sodium caprate (C10) and salcaprozate sodium (SNAC)
44. Formulation, Characterisation and Evaluation of the Antihypertensive Peptides, Isoleucine-Proline-Proline and Leucine-Lysine-Proline in Chitosan Nanoparticles Coated with Zein for Oral Drug Delivery
45. Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat
46. An intra-articular salmon calcitonin-based nanocomplex reduces experimental inflammatory arthritis
47. Colonic absorption of salmon calcitonin using tetradecyl maltoside (TDM) as a permeation enhancer
48. Editorial overview: New technologies: drug delivery and medical devices combinations, more than the sum of the parts
49. Zinc sulphate attenuates chloride secretion in Human colonic mucosae in vitro
50. Evaluation of alkylmaltosides as intestinal permeation enhancers: Comparison between rat intestinal mucosal sheets and Caco-2 monolayers
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