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38 results on '"Bravo J.C."'

1. Manufacturing reflection holographic couplers for see-through applications recorded in photopolymers without prisms: An experimental validation

Author

Sirvent-Verdú J.J., Bravo J.C., Colomina-Martínez J., Nájar G., Neipp C., Francés J., Gallego S., and Beléndez A.

Subjects
holography, photopolymers, see-through, holographic couplers, reflection holograms, Applied optics. Photonics, TA1501-1820, Optics. Light, QC350-467
Abstract

In the present work, the viability of a novel recording geometry to produce reflection holographic couplers is analyzed. Recalling the idea of previous works, photopolymers are used as the recording material because they have been proven to be well-suited for the intended see-through application: the capability to provide a virtual image without compromising the information about the surrounding environment. Moreover, holography fundamentals give us the proper background to examine the proposed design, where no prisms or microlenses arrays are used. Aiming to support the analysis, we provide experimental evidence that the produced reflection holographic gratings exhibit the correct properties to work as a coupler, where the sensitivity of the material and its properties are studied and examined.

Published
2024
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2. Manufacturing reflection holographic couplers for see-through applications recorded in photopolymers without prisms: An experimental validation

Author

Sirvent-Verdú J.J., Bravo J.C., Colomina-Martínez J., Piñol-Galera C., Nájar G., Neipp C., Francés J., Gallego S., and Beléndez A.

Subjects
Physics, QC1-999
Abstract

In the present work, the viability of a novel recording geometry to produce reflection holographic couplers is analyzed. Recalling the idea of previous works, photopolymers are used as the recording material, as they are well-suited for the intended see-through application. Moreover, Kogelnik’s theory fundamentals give us the proper background to examine the proposed design, where no prisms or microlenses arrays are used. Aiming to support the analysis, we provide experimental evidence that the produced gratings exhibit the correct properties to work as a coupler.

Published
2023
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12. Long term follow up of patients treated for Helicobacter pylori infection

Author

Mera, R., Fontham, E.T.H., Bravo, L.E., Bravo, J.C., Piazuelo, M.B., Camargo, M.C., and Correa, P.

Subjects
Stomach cancer -- Development and progression, Helicobacter infections -- Care and treatment, Helicobacter infections -- Complications and side effects, Long-term care of the sick -- Research, Health
Published
2005

13. Epstein-Barr virus in gastric adenocarcinomas: association with ethnicity and CDKN2A promoter methylation. (Original Article)

Author

Vo, Q.N., Geradts, J., Gulley, M.L., Boudreau, D.A., Bravo, J.C., and Schneider, B.G.

Subjects
Adenocarcinoma -- Physiological aspects, Stomach cancer -- Physiological aspects, Epstein-Barr virus -- Physiological aspects, Health, Physiological aspects
Abstract

Aims: It has been shown previously (by immunohistochemistry) that gastric adenocarcinomas harbouring Epstein-Barr virus (EBV) frequently lose p16 protein. This study aimed to examine the mechanisms of inactivation of the [...]

Published
2002

15. Regions of allelic imbalance in the distal portion of chromosome 12q in gastric cancer. (Original Article)

Author

Schneider, B.G., Rha, S.Y., Chung, H.C., Bravo, J.C., Mera, R., Torres, J.C., Plaisance, Jr., K.T., Schlegel, R., McBride, C.M., Reveles, X.T., and Leach, R.J.

Subjects
Tumor suppressor genes -- Physiological aspects -- Research -- Genetic aspects, Human chromosome abnormalities -- Physiological aspects -- Research -- Genetic aspects, Cancer -- Genetic aspects, Stomach cancer -- Genetic aspects -- Physiological aspects -- Research, Allelomorphism -- Physiological aspects -- Research -- Genetic aspects, Health, Physiological aspects, Research, Genetic aspects
Abstract

Aims: To define regions of loss on the distal portion of chromosome 1 2q in gastric adenocarcinoma. Methods: Microsatellite analysis on chromosome 12 was performed on 19 human gastric cancer [...]

Published
2003

19. Distribution, fractionation and mobility assessment of heavy metals in a spiked soil using a multi-species soil system

Author

Carbonell, G., Bravo, J.C., López-Mancisidor, P., Pro, J., Fernández Torija, C., and Tarazona, J.V.

Subjects
ENVIRONMENT AND ECOLOGY, AGRICULTURAL SOILS, ORGANIC AMENDMENTS, HEAVY METALS, BIOAVAILABILITY, SOIL TRANSPORT PROCESSES, SOIL TOXICITY, SOIL POLLUTION, SIMULATION MODELS, EXPERIMENTATION, SUELOS AGRICOLAS, ENMIENDAS ORGANICAS, METALES PESADOS, BIODISPONIBILIDAD, PROCESOS DE TRANSPORTE EN EL SUELO, TOXICIDAD DEL SUELO, POLUCION DEL SUELO, MODELOS DE SIMULACION, EXPERIMENTACION
Abstract

The concentration, distribution and fractionation of metals in a metal spiked soils were studied using a Multi-Species-Soil-System (MSx3), a terrestrial microcosms that allows a combined assessment of the chemical fate and effects on terrestrial organisms. Samples of a natural soil were spiked with a mixture of the metals Cd, Co, Cr, Cu, Mn, Ni, Pb and Zn and placed on the top of soil columns simulating the heavy metal concentration due to an agricultural organic amendment (manure, sewage sludge) equivalent to 2, 5 and 10 times the original background of soil metal concentration. After 21 days exposure, metal mobility was assessed using three complementary approaches: the metal concentrations at four depths in the soil profiles (I, II, III and IV), the metal fractionation in the top soil and the percent metal detected in leachates. The upper soil profile had the highest metal concentration for the majority of the metals. For Cd, Mn and Co highest concentrations were in the bottom profile. Maximum metal mobility in leachates was for Cd (24.67%) >Co (3.65%) >Mn (3.18%) >Zn (0.55%) > and Cu (0.012%). Nickel and Cr percentages were ,0.1%. Lead mobility from soil to water was 0.004% and 0.008% for the lowest and highest treatments, respectively., En un suelo control fortificado con una mezcla de metales (Cd, Co, Cr, Cu, Mn, Ni, Pb, Zn), se ha estudiado la concentración, distribución y fraccionamiento de metales utilizando un microcosmos terrestre, Multi-Species-Soil-System (MSx3), que permite conocer el destino y los efectos de contaminantes sobre los organismos del suelo. Se fortificaron muestras de un suelo control con la mezcla de metales mencionada y se colocaron en la parte superior de las columnas de suelo, simulando el contenido de metales pesados que contiene una enmienda agraria, con residuos orgánicos (composts de residuos sólidos urbanos, lodos de depuradora), equivalente a 2, 5 y 10 veces la concentración basal de metales en el suelo control utilizado. Después de 21 días de exposición, se determinó la movilidad de los metales usando tres aproximaciones complementarias: la concentración de metales en los cuatro perfiles en que la columna de suelo fue dividida (I, II, III y IV), el fraccionamiento secuencial en el perfil superior del suelo y el porcentaje de metales que llega a los lixiviados. El perfil superior mostró, para la mayoría de los metales considerados, las concentraciones más altas, mientras que las concentraciones más elevadas de Cd, Mn y Co aparecieron en el perfil más profundo. En los lixiviados procedentes de las columnas tratadas con la mayor dosis de metales (10x) se detectaron Cd (24,67%) >Co (3,65%) > Mn (3,18%) ,> Zn (0,55%) > Cu (0,012%); sin embargo los valores Ni y Cr en estos mismos lixiviados fueron 0,1% se encontraron para Co en cualquiera de los lixiviados, tratados o control. La movilidad del Pb fue 0,004% y 0,008% para las dosis más baja y más alta respectivamente.

Published
2009

21. Non-active power multivector

Author

Bravo, J.C., primary, Castilla, M., additional, Montano, J.C., additional, Ordonez, M., additional, Castilla, M. V., additional, Lopez, A., additional, Borras, D., additional, and Gutierrez, J., additional

Published
2010
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31. Antioxidant micronutrients and gastric cancer

Author

Correa, P., primary, Malcom, G., additional, Schmidt, B., additional, Fontham, E., additional, Ruiz, B., additional, Bravo, J.C., additional, Bravo, L.E., additional, Zarama, G., additional, and Realpe, J.L., additional

Published
1998
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32. Loss of p16/CDKN2A tumor suppressor protein in gastric adenocarcinoma is associated with epstein-barr virus and anatomic location in the body of the stomach

Author

Schneider, B.G., Gulley, M.L., Eagan, P., Bravo, J.C., Mera, R., and Geradts, J.

Abstract

Gastric adenocarcinomas (n = 125) were analyzed by immunohistochemistry for the presence of p16, the CDKN2A gene product. This protein was lost in 31 of 125 cases (25%), and loss was associated with location of the tumor in the body of the stomach (P = .001). Loss of p16 was also associated with the presence of Epstein-Barr virus (EBV) in tumor cells as determined by in situ hybridization (P = .022). This effect may relate to anatomic site, because EBV-associated tumors originate more frequently in the body of the stomach. When p16 status was evaluated for ethnic origin of the patient (non-Hispanic white, Hispanic, or black), a strong trend (P = .057) was found for African-American patients to have fewer p16-negative tumors than other patients. This also may relate to anatomic location, because fewer tumors from black patients arose in the body of the stomach (P = .022). No significant associations were detected between p16 status and histological subtype (intestinal v diffuse), the presence of microsatellite instability, grade or stage of the tumor, or age, gender, or survival of the patient. In conclusion, p16 loss is quite common in gastric adenocarcinoma, and such loss is more common in EBV-infected tumors arising in the body of the stomach.

Published
2000
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33. Sulphomucins favour adhesion of Helicobacter pylori to metaplastic gastric mucosa

Author

Bravo, J.C. and Correa, P.

Abstract

AimsTo assess the influence of sulphomucin secretion on Helicobacter pylori colonisation and adhesion to metaplastic gastric cells.MethodsGastric biopsies from 230 H pylori positive patients with intestinal metaplasia were analysed. Sulphated mucins and H pylori were visualised using a new technique combining high iron diamine-alcian blue mucin stains with the Steiner silver stain for the bacteria.ResultsSulphomucin secretion anywhere in the mucosa and a histological diagnosis of dysplasia increase the risk of H pylori adhesion to metaplastic cells (odds ratios 19.9 and 4.3, respectively). However, only 9.4% of cases showing sulphomucin secretion and 10.8% of cases with dysplasia had evidence of adhesion of H pylori bacteria to metaplastic cells.ConclusionsThe findings suggest that H pylori may play a role in the advanced stages of carcinogenesis. It will be of interest to investigate if the relative small proportion of type III metaplasias that actually progress to carcinoma show persistence of H pylori.

Published
1999

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