2,297 results on '"Braunwald E"'
Search Results
2. Risk and benefits of baseline antiplatelet therapy in 58,598 patients with atrial fibrillation randomized to NOACs vs warfarin
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Patel, S, primary, Palazzolo, M G, additional, Antman, E M, additional, Braunwald, E, additional, Carnicelli, A P, additional, Connolly, S J, additional, Granger, C B, additional, Patel, M R, additional, Wallentin, L, additional, Ruff, C T, additional, and Giugliano, R P, additional
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- 2023
- Full Text
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3. Impact of Sacubitril/Valsartan Versus Ramipril on Total Heart Failure Events in the PARADISE-MI Trial
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Pfeffer, M, Claggett, B, Lewis, E, Granger, C, Kober, L, Maggioni, A, Mann, D, Mcmurray, J, Rouleau, J, Solomon, S, Steg, P, Berwanger, O, Cikes, M, De Pasquale, C, Fernandez, A, Filippatos, G, Jering, K, Landmesser, U, Menon, V, Merkely, B, Petrie, M, Petrov, I, Schou, M, Senni, M, Sim, D, van der Meer, P, Lefkowitz, M, Zhou, Y, Wang, Y, Braunwald, E, Pfeffer M. A., Claggett B., Lewis E. F., Granger C. B., Kober L., Maggioni A. P., Mann D. L., McMurray J. J. V., Rouleau J. -L., Solomon S. D., Steg P. G., Berwanger O., Cikes M., De Pasquale C. G., Fernandez A., Filippatos G., Jering K., Landmesser U., Menon V., Merkely B., Petrie M. C., Petrov I., Schou M., Senni M., Sim D., van der Meer P., Lefkowitz M., Zhou Y., Wang Y., Braunwald E., Pfeffer, M, Claggett, B, Lewis, E, Granger, C, Kober, L, Maggioni, A, Mann, D, Mcmurray, J, Rouleau, J, Solomon, S, Steg, P, Berwanger, O, Cikes, M, De Pasquale, C, Fernandez, A, Filippatos, G, Jering, K, Landmesser, U, Menon, V, Merkely, B, Petrie, M, Petrov, I, Schou, M, Senni, M, Sim, D, van der Meer, P, Lefkowitz, M, Zhou, Y, Wang, Y, Braunwald, E, Pfeffer M. A., Claggett B., Lewis E. F., Granger C. B., Kober L., Maggioni A. P., Mann D. L., McMurray J. J. V., Rouleau J. -L., Solomon S. D., Steg P. G., Berwanger O., Cikes M., De Pasquale C. G., Fernandez A., Filippatos G., Jering K., Landmesser U., Menon V., Merkely B., Petrie M. C., Petrov I., Schou M., Senni M., Sim D., van der Meer P., Lefkowitz M., Zhou Y., Wang Y., and Braunwald E.
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- 2022
4. Long-term safety and efficacy of anacetrapib in patients with atherosclerotic vascular disease
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Sammons, E, Hopewell, JC, Chen, F, Stevens, W, Wallendszus, K, Valdes-Marquez, E, Dayanandan, R, Knott, C, Murphy, K, Wincott, E, Baxter, A, Goodenough, R, Lay, M, Hill, M, Macdonnell, S, Fabbri, G, Lucci, D, Fajardo-Moser, M, Brenner, S, Hao, D, Zhang, H, Liu, J, Wuhan, B, Mosegaard, S, Herrington, W, Wanner, C, Angermann, C, Ertl, G, Maggioni, A, Barter, P, Mihaylova, B, Mitchel, Y, Blaustein, R, Goto, S, Tobert, J, DeLucca, P, Chen, Y, Chen, Z, Gray, A, Haynes, R, Armitage, J, Baigent, C, Wiviott, S, Cannon, C, Braunwald, E, Collins, R, Bowman, L, Landray, M, and Group, HPS3/TIMI55-REVEAL Collaborative
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Cardiology and Cardiovascular Medicine - Abstract
Aims REVEAL was the first randomized controlled trial to demonstrate that adding cholesteryl ester transfer protein inhibitor therapy to intensive statin therapy reduced the risk of major coronary events. We now report results from extended follow-up beyond the scheduled study treatment period. Methods and results A total of 30 449 adults with prior atherosclerotic vascular disease were randomly allocated to anacetrapib 100 mg daily or matching placebo, in addition to open-label atorvastatin therapy. After stopping the randomly allocated treatment, 26 129 survivors entered a post-trial follow-up period, blind to their original treatment allocation. The primary outcome was first post-randomization major coronary event (i.e. coronary death, myocardial infarction, or coronary revascularization) during the in-trial and post-trial treatment periods, with analysis by intention-to-treat. Allocation to anacetrapib conferred a 9% [95% confidence interval (CI) 3–15%; P = 0.004] proportional reduction in the incidence of major coronary events during the study treatment period (median 4.1 years). During extended follow-up (median 2.2 years), there was a further 20% (95% CI 10–29%; P Conclusion The beneficial effects of anacetrapib on major coronary events increased with longer follow-up, and no adverse effects emerged on non-vascular mortality or morbidity. These findings illustrate the importance of sufficiently long treatment and follow-up duration in randomized trials of lipid-modifying agents to assess their full benefits and potential harms. Trial registration International Standard Randomized Controlled Trial Number (ISRCTN) 48678192; ClinicalTrials.gov No. NCT01252953; EudraCT No. 2010-023467-18.
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- 2022
5. Prognostic importance of NT-proBNP following high-risk myocardial infarction in the PARADISE-MI Trial
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Jering, K, primary, Claggett, B, additional, Pfeffer, M A, additional, Granger, C, additional, Kober, L, additional, Lewis, E F, additional, Maggioni, A P, additional, Mann, D L, additional, McMurray, J J V, additional, Prescott, M F, additional, Rouleau, J L, additional, Solomon, S D, additional, Steg, P G, additional, Von Lewinski, D, additional, and Braunwald, E, additional
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- 2022
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6. PARADISE-MI – event rates and treatment effect of sacubitril/valsartan v ramipril by the presence or absence of transient pulmonary congestion and/or LVEF less or greater than 40
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Petrie, M, primary, Solomon, S, additional, Claggett, B L, additional, Jering, K, additional, Steg, G, additional, Granger, C, additional, Lewis, E, additional, Kober, L, additional, Mann, D, additional, Rouleau, J L, additional, McMurray, J J, additional, Maggioni, A, additional, Braunwald, E, additional, and Pfeffer, M A, additional
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- 2022
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7. Lipoprotein(a), cardiovascular events, and benefit of P2Y12 inhibition: insights from the PEGASUS-TIMI 54 trial
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Patel, S, primary, Morrow, D, additional, Bonaca, M, additional, Palazzolo, M, additional, Jarolim, P, additional, Steg, P G, additional, Bhatt, D, additional, Storey, R, additional, Cohen, M, additional, Braunwald, E, additional, Sabatine, M, additional, and O'Donoghue, M, additional
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- 2022
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8. Angiotensin receptor–neprilysin inhibition in acute myocardial infarction
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Pfeffer, M, Claggett, B, Lewis, E, Granger, C, Kober, L, Maggioni, A, Mann, D, Mcmurray, J, Rouleau, J, Solomon, S, Steg, P, Berwanger, O, Cikes, M, De Pasquale, C, East, C, Fernandez, A, Jering, K, Landmesser, U, Mehran, R, Merkely, B, Mody, F, Petrie, M, Petrov, I, Schou, M, Senni, M, Sim, D, van der Meer, P, Lefkowitz, M, Zhou, Y, Gong, J, Braunwald, E, Pfeffer M. A., Claggett B., Lewis E. F., Granger C. B., Kober L., Maggioni A. P., Mann D. L., McMurray J. J. V., Rouleau J. -L., Solomon S. D., Steg P. G., Berwanger O., Cikes M., De Pasquale C. G., East C., Fernandez A., Jering K., Landmesser U., Mehran R., Merkely B., Mody F. V., Petrie M. C., Petrov I., Schou M., Senni M., Sim D., van der Meer P., Lefkowitz M., Zhou Y., Gong J., Braunwald E., Pfeffer, M, Claggett, B, Lewis, E, Granger, C, Kober, L, Maggioni, A, Mann, D, Mcmurray, J, Rouleau, J, Solomon, S, Steg, P, Berwanger, O, Cikes, M, De Pasquale, C, East, C, Fernandez, A, Jering, K, Landmesser, U, Mehran, R, Merkely, B, Mody, F, Petrie, M, Petrov, I, Schou, M, Senni, M, Sim, D, van der Meer, P, Lefkowitz, M, Zhou, Y, Gong, J, Braunwald, E, Pfeffer M. A., Claggett B., Lewis E. F., Granger C. B., Kober L., Maggioni A. P., Mann D. L., McMurray J. J. V., Rouleau J. -L., Solomon S. D., Steg P. G., Berwanger O., Cikes M., De Pasquale C. G., East C., Fernandez A., Jering K., Landmesser U., Mehran R., Merkely B., Mody F. V., Petrie M. C., Petrov I., Schou M., Senni M., Sim D., van der Meer P., Lefkowitz M., Zhou Y., Gong J., and Braunwald E.
- Abstract
BACKGROUND In patients with symptomatic heart failure, sacubitril–valsartan has been found to reduce the risk of hospitalization and death from cardiovascular causes more effectively than an angiotensin-converting–enzyme inhibitor. Trials comparing the effects of these drugs in patients with acute myocardial infarction have been lacking. METHODS We randomly assigned patients with myocardial infarction complicated by a reduced left ventricular ejection fraction, pulmonary congestion, or both to receive either sacubitril–valsartan (97 mg of sacubitril and 103 mg of valsartan twice daily) or ramipril (5 mg twice daily) in addition to recommended therapy. The primary outcome was death from cardiovascular causes or incident heart failure (outpatient symptomatic heart failure or heart failure leading to hospitalization), whichever occurred first. RESULTS A total of 5661 patients underwent randomization; 2830 were assigned to receive sacubitril–valsartan and 2831 to receive ramipril. Over a median of 22 months, a primary-outcome event occurred in 338 patients (11.9%) in the sacubitril–valsartan group and in 373 patients (13.2%) in the ramipril group (hazard ratio, 0.90; 95% confidence interval [CI], 0.78 to 1.04; P=0.17). Death from cardiovascular causes or hospitalization for heart failure occurred in 308 patients (10.9%) in the sacubitril–valsartan group and in 335 patients (11.8%) in the ramipril group (hazard ratio, 0.91; 95% CI, 0.78 to 1.07); death from cardiovascular causes in 168 (5.9%) and 191 (6.7%), respectively (hazard ratio, 0.87; 95% CI, 0.71 to 1.08); and death from any cause in 213 (7.5%) and 242 (8.5%), respectively (hazard ratio, 0.88; 95% CI, 0.73 to 1.05). Treatment was discontinued because of an adverse event in 357 patients (12.6%) in the sacubitril–valsartan group and 379 patients (13.4%) in the ramipril group. CONCLUSIONS Sacubitril–valsartan was not associated with a significantly lower incidence of death from cardiovascular causes or incident hear
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- 2021
9. Atrial amyloidosis: mechanisms and clinical manifestations
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Vergaro, G, Aimo, A, Rapezzi, C, Castiglione, V, Fabiani, I, Pucci, A, Buda, G, Passino, C, Lupon, J, Bayes-Genis, A, Emdin, M, and Braunwald, E
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Atrial disease ,Heart ,Amyloidosis ,Natriuretic peptides ,Atrial fibrillation - Abstract
Cardiac amyloidosis (CA) is now recognized as an important cause of heart failure. Increased wall thickness and diastolic dysfunction of the left ventricle are the most easily detectable manifestations of CA, but amyloid accumulates in all cardiac structures. Involvement of the left and right atria may be due to the haemodynamic effects of ventricular diastolic dysfunction, the effects of amyloid infiltration into the atrial wall, and the cardiotoxic damage of atrial cardiomyocytes by amyloid precursors. Atrial amyloidosis is an early manifestation of CA, and is associated with an increased risk of atrial fibrillation and thromboembolic events. Furthermore, atrial amyloidosis can be found even in the absence of systemic disease and ventricular involvement. This condition is named isolated atrial amyloidosis and is due to a local overproduction of atrial natriuretic peptide. In this review we summarize the evidence on the mechanisms and clinical relevance of atrial amyloidosis.
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- 2022
10. Unstable Angina: A Classification
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Braunwald, E., Bleifeld, Walter, editor, Hamm, Christian W., editor, and Braunwald, Eugene, editor
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- 1990
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11. Epistaxis in anticoagulated patients with atrial fibrillation in the ENGAGE AF-TIMI 48 trial
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Semco, R S, primary, Bergmark, B A, additional, Bergmark, R W, additional, Murphy, S A, additional, Ruff, C T, additional, Antman, E M, additional, Braunwald, E, additional, and Giugliano, R P, additional
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- 2021
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12. Edoxaban vs. warfarin in patients with atrial fibrillation on amiodarone: a subgroup analysis of the ENGAGE AF-TIMI 48 trial
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Steffel, J., Giugliano, R.P., Braunwald, E., Murphy, S.A., Atar, D., Heidbuchel, H., Camm, A.J., Antman, E.M., and Ruff, C.T.
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- 2015
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13. Impact of treatment with saxagliptin on glycaemic stability and β-cell function in the SAVOR-TIMI 53 study
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Leibowitz, G., Cahn, A., Bhatt, D. L., Hirshberg, B., Mosenzon, O., Wei, C., Jermendy, G., Sheu, W. H.-H., Sendon, J. L., Im, K., Braunwald, E., Scirica, B. M., and Raz, I.
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- 2015
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14. Rivaroxaban versus placebo in patients with acute coronary syndromes (ATLAS ACS-TIMI 46): a randomised, double-blind, phase II trial
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Mega, JL, Braunwald, E, Mohanavelu, S, Burton, P, Poulter, R, Misselwitz, F, Hricak, V, Barnathan, ES, Bordes, P, Witkowski, A, Markov, V, Oppenheimer, L, and Gibson, CM
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- 2009
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15. Angiotensin Receptor-Neprilysin Inhibition in Acute Myocardial Infarction
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Pfeffer, MA, Claggett, B, Lewis, EF, Granger, CB, Kober, L, Maggioni, AP, Mann, DL, McMurray, JJV, Rouleau, JL, Solomon, SD, Steg, PG, Berwanger, O, Cikes, M, De Pasquale, CG, East, C, Fernandez, A, Jering, K, Landmesser, U, Mehran, R, Merkely, B, Mody, FV, Petrie, MC, Petrov, I, Schou, M, Senni, M, Sim, D, van der Meer, P, Lefkowitz, M, Zhou, Y, Gong, J, Braunwald, E, Sionis A., and PARADISE-MI Invest & Comm
- Abstract
Sacubitril-Valsartan in Acute Myocardial Infarction In a randomized trial, 5661 patients with acute myocardial infarction and a reduced left ventricular ejection fraction, pulmonary congestion, or both were assigned to receive either sacubitril-valsartan or ramipril. At a median of 22 months, there was no significant difference between the two groups in the incidence of death from cardiovascular causes or incident heart failure. Background In patients with symptomatic heart failure, sacubitril-valsartan has been found to reduce the risk of hospitalization and death from cardiovascular causes more effectively than an angiotensin-converting-enzyme inhibitor. Trials comparing the effects of these drugs in patients with acute myocardial infarction have been lacking. Methods We randomly assigned patients with myocardial infarction complicated by a reduced left ventricular ejection fraction, pulmonary congestion, or both to receive either sacubitril-valsartan (97 mg of sacubitril and 103 mg of valsartan twice daily) or ramipril (5 mg twice daily) in addition to recommended therapy. The primary outcome was death from cardiovascular causes or incident heart failure (outpatient symptomatic heart failure or heart failure leading to hospitalization), whichever occurred first. Results A total of 5661 patients underwent randomization; 2830 were assigned to receive sacubitril-valsartan and 2831 to receive ramipril. Over a median of 22 months, a primary-outcome event occurred in 338 patients (11.9%) in the sacubitril-valsartan group and in 373 patients (13.2%) in the ramipril group (hazard ratio, 0.90; 95% confidence interval [CI], 0.78 to 1.04; P=0.17). Death from cardiovascular causes or hospitalization for heart failure occurred in 308 patients (10.9%) in the sacubitril-valsartan group and in 335 patients (11.8%) in the ramipril group (hazard ratio, 0.91; 95% CI, 0.78 to 1.07); death from cardiovascular causes in 168 (5.9%) and 191 (6.7%), respectively (hazard ratio, 0.87; 95% CI, 0.71 to 1.08); and death from any cause in 213 (7.5%) and 242 (8.5%), respectively (hazard ratio, 0.88; 95% CI, 0.73 to 1.05). Treatment was discontinued because of an adverse event in 357 patients (12.6%) in the sacubitril-valsartan group and 379 patients (13.4%) in the ramipril group. Conclusions Sacubitril-valsartan was not associated with a significantly lower incidence of death from cardiovascular causes or incident heart failure than ramipril among patients with acute myocardial infarction. (Funded by Novartis; PARADISE-MI ClinicalTrials.gov number, .)
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- 2021
16. A new initiative of the European Heart Journal: the Desmond Julian Award
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Crea, Filippo, Braunwald, E., Crea F. (ORCID:0000-0001-9404-8846), Crea, Filippo, Braunwald, E., and Crea F. (ORCID:0000-0001-9404-8846)
- Abstract
N/a
- Published
- 2021
17. Comparison of the Efficacy and Safety Outcomes of Edoxaban in 8040 Women Versus 13 065 Men with Atrial Fibrillation in the ENGAGE AF-TIMI 48 Trial
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Zelniker, T. A., Ardissino, M., Andreotti, F., O'Donoghue, M. L., Yin, O., Park, J. -G., Murphy, S. A., Ruff, C. T., Lanz, H. J., Antman, E. M., Braunwald, E., Giugliano, R. P., Merlini, P. A., Andreotti F. (ORCID:0000-0002-1456-6430), Zelniker, T. A., Ardissino, M., Andreotti, F., O'Donoghue, M. L., Yin, O., Park, J. -G., Murphy, S. A., Ruff, C. T., Lanz, H. J., Antman, E. M., Braunwald, E., Giugliano, R. P., Merlini, P. A., and Andreotti F. (ORCID:0000-0002-1456-6430)
- Abstract
Background: Female sex is an independent risk factor for stroke and systemic embolic events in patients with atrial fibrillation. This study aimed to examine the efficacy and safety profile of edoxaban in women versus men. Methods: The ENGAGE AF-TIMI 48 trial (Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48) randomly assigned 21 105 patients (8040 women) with atrial fibrillation and CHADS2 score ≥2 either to a higher-dose edoxaban regimen, a lower-dose edoxaban regimen, or warfarin. The primary end points of the trial were the composite of stroke or systemic embolic events (efficacy), and International Society on Thrombosis and Haemostasis-defined major bleeding (safety). Results: In comparison with men, women were older, had lower body weight, were more likely to have hypertension and renal dysfunction, but less likely to smoke, drink alcohol, or have diabetes or coronary artery disease. Pretreatment endogenous factor Xa activity was significantly higher in women than in men (92.5% versus 86.1%, P<0.001). Treatment with edoxaban in women resulted in greater peak edoxaban concentration and inhibition of endogenous factor Xa in comparison with men, resulting in similar endogenous factor Xa activity between the sexes 2 to 4 hours after dose. Treatment with higher-dose edoxaban regimen (versus warfarin) resulted in similar reduction in the risk of stroke/systemic embolic events (women: hazard ratio [HR], 0.87 [0.69-1.11], men: HR, 0.87 [0.71-1.06]; P-interaction=0.97) and major bleeding (women: HR, 0.74 [0.59-0.92], men: HR, 0.84 [0.72-0.99]; P-interaction=0.34) in women and men. However, women assigned to higher-dose edoxaban regimen experienced greater reductions in hemorrhagic stroke (HR, 0.30 [95% CI, 0.15-0.59] versus HR, 0.70 [95% CI, 0.46-1.06]), intracranial bleeding (HR, 0.20 [95% CI, 0.10-0.39] versus HR, 0.63 [95% CI, 0.44-0.89]), and life-threatening or fatal bleeding (HR, 0.25 [95%
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- 2021
18. Supplement to: Vorapaxar in the secondary prevention of atherothrombotic events.
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Morrow, D A, Braunwald, E, and Bonaca, M P
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- 2012
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19. Free Communications 9: Large clinical trials 2 Efficacy and safety of edoxaban vs. warfarin in high-risk patients: The ENGAGE AF-TIMI 48 trial: WSC-1119
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Rost, N S, Giugliano, R P, Ruff, C T, Murphy, S A, Crompton, A E, Mercuri, M, Antman, E M, and Braunwald, E M
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- 2014
20. Atrial Failure as a Clinical Entity: JACC Review Topic of the Week
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Bisbal F, Baranchuk A, Braunwald E, Bayés de Luna A, and Bayés-Genís A
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atrial failure, atrial fibrillation, atrial function, heart failure, interatrial block, stroke ,cardiovascular system ,cardiovascular diseases - Abstract
Atrial dysfunction has been widely considered a marker or consequence of other cardiac conditions rather than the cause itself. Here, we propose the term atrial failure as a clinically relevant entity, defined as any atrial dysfunction causing impaired heart performance, symptoms, and worsening quality of life or life expectancy. Aspects of the etiology, mechanisms, and consequences of atrial failure are discussed. Recent advances in cardiac electrophysiology and imaging have improved our understanding of the highly complex atrial anatomy and function, underlying the paramount importance of the atria in optimal heart performance. It is time to reappraise the concept of the failing atrium as a primary cause or aggravating factor of the symptoms in many of our patients. The concept of atrial failure may foster basic and translational research to gain a better understanding of how to identify and manage atrial dysfunction.
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- 2020
21. Conducting clinical trials in heart failure during (and after) the COVID-19 pandemic: An Expert Consensus Position Paper from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)
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Anker, S.D. Butler, J. Khan, M.S. Abraham, W.T. Bauersachs, J. Bocchi, E. Bozkurt, B. Braunwald, E. Chopra, V.K. Cleland, J.G. Ezekowitz, J. Filippatos, G. Friede, T. Hernandez, A.F. Lam, C.S.P. Lindenfeld, J. McMurray, J.J.V. Mehra, M. Metra, M. Packer, M. Pieske, B. Pocock, S.J. Ponikowski, P. Rosano, G.M.C. Teerlink, J.R. Tsutsui, H. Van Veldhuisen, D.J. Verma, S. Voors, A.A. Wittes, J. Zannad, F. Zhang, J. Seferovic, P. Coats, A.J.S.
- Abstract
The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has important implications for the safety of participants in clinical trials and the research staff caring for them and, consequently, for the trials themselves. Patients with heart failure may be at greater risk of infection with COVID-19 and the consequences might also be more serious, but they are also at risk of adverse outcomes if their clinical care is compromised. As physicians and clinical trialists, it is our responsibility to ensure safe and effective care is delivered to trial participants without affecting the integrity of the trial. The social contract with our patients demands no less. Many regulatory authorities from different world regions have issued guidance statements regarding the conduct of clinical trials during this COVID-19 crisis. However, international trials may benefit from expert guidance from a global panel of experts to supplement local advice and regulations, thereby enhancing the safety of participants and the integrity of the trial. Accordingly, the Heart Failure Association of the European Society of Cardiology on 21 and 22 March 2020 conducted web-based meetings with expert clinical trialists in Europe, North America, South America, Australia, and Asia. The main objectives of this Expert Position Paper are to highlight the challenges that this pandemic poses for the conduct of clinical trials in heart failure and to offer advice on how they might be overcome, with some practical examples. While this panel of experts are focused on heart failure clinical trials, these discussions and recommendations may apply to clinical trials in other therapeutic areas. © 2020 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2020.
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- 2020
22. Heart Failure: An Update
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Braunwald, E
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- 2013
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23. Baseline characteristics of the patient population in the Saxagliptin Assessment of Vascular Outcomes Recorded in patients with diabetes mellitus (SAVOR)-TIMI 53 trial†
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Mosenzon, O., Raz, I., Scirica, B. M., Hirshberg, B., Stahre, C. I., Steg, P. G., Davidson, J., Ohman, P., Price, D. L., Frederich, B., Udell, J. A., Braunwald, E., and Bhatt, D. L.
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- 2013
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24. Serial measurement of biomarkers and the risk of stroke or systemic embolism and bleeding in patients with atrial fibrillation in ENGAGE AF-TIMI 48
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Oyama, K, primary, Giugliano, R, additional, Berg, D, additional, Ruff, C, additional, Tang, M, additional, Murphy, S, additional, Lanz, H, additional, Grosso, M, additional, Antman, E, additional, Braunwald, E, additional, and Morrow, D, additional
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- 2020
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25. Is there a role for half-dose anticoagulation in atrial fibrillation? Randomized comparison of 2 doses of edoxaban in 14,014 patients in ENGAGE AF-TIMI 48
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Steffel, J, primary, Ruff, C.T, additional, Braunwald, E, additional, Park, J.G, additional, Murphy, S, additional, Antman, E.M, additional, and Giugliano, R.P, additional
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- 2020
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26. Meeting Report: ESC Forum on Drug Eluting Stents European Heart House, Nice, 27–28 September 2007
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Daemen, Joost, Simoons, Maarten L., Wijns, William, Bagust, Adrian, Bos, Gert, Bowen, James M., Braunwald, Eugene, Camenzind, Edoardo, Chevalier, Bernard, DiMario, Carlo, Fajadet, Jean, Gitt, Anselm, Guagliumi, Giulio, Hillege, Hans L., James, Stefan, Jüni, Peter, Kastrati, Adnan, Kloth, Sabine, Kristensen, Steen D., Krucoff, Mitchell, Legrand, Victor, Pfisterer, Matthias, Rothman, Martin, Serruys, Patrick W., Silber, Sigmund, Steg, Philippe G., Tariah, Ibrahim, Wallentin, Lars, Windecker, Stephan W., Aimonetti, A., Allocco, D., Baczynska, A., Bagust, A., Berenger, M., Bos, G., Boam, A., Bowen, J.M., Braunwald, E., Calle, J.P., Camenzind, E., Campo, G., Carlier, S., Chevalier, B., Daemen, J., de Schepper, J., Di Bisceglie, G., DiMario, C., Dobbels, H., Fajadet, J., Farb, A., Ghislain, J.C., Gitt, A., Guagliumi, G., Hellbardt, S., Hillege, H.L., ten Hoedt, R., Isaia, C., James, S., de Jong, P., Jüni, P., Kastrati, A., Klasen, E., Kloth, S., Kristensen, S.D., Krucoff, M., Legrand, V., Lekehal, M., LeNarz, L., Ni Mhullain, F., Nagai, H., Patteet, A., Paunovic, D., Pfisterer, M., Potgieter, A., Purdy, I., Raveau-Landon, C., Rothman, M., Serruys, P.W., Silber, S., Simoons, M.L., Steg, P.G., Tariah, I., Ternstrom, S., Van Wuytswinkel, J., Waliszewski, M., Wallentin, L., Wijns, W., and Windecker, S.W.
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- 2009
27. Foreword
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BRAUNWALD, E, primary
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- 2004
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28. Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials
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Fulcher, J, Mihaylova, B, O'Connell, R, Emberson, J, Blackwell, L, Reith, C, Koren, M, Tonkin, A, Ridker, P, Barnes, E, Ford, I, Kean, S, Trompet, S, Macfarlane, P, Cannon, C, Pedersen, TR, Wilhelmsen, L, LaRosa, J, Packard, C, Robertson, M, Young, R, Tobert, J, Flather, M, Goto, S, Kastelein, J, Newman, C, Shear, C, Varigos, J, White, H, Armitage, J, Davies, K, Halls, H, Harper, C, Herrington, W, Holland, L, Kirby, A, Oconnell, R, Preiss, D, Spata, E, Wilson, K, Lonn, E, Wanner, C, Koenig, W, Gotto, A, Kjekshus, J, Yusuf, S, Collins, R, Simes, J, Baigent, C, Keech, A, De Lemos, J, Braunwald, E, Blazing, M, Murphy, S, Downs, JR, Clearfield, M, Holdaas, H, Gordon, D, Davis, B, Dahlof, B, Poulter, N, Sever, P, Knopp, RH, Fellstrom, B, Jardine, A, Schmieder, R, Zannad, F, Colhoun, HM, Betteridge, DJ, Durrington, PN, Hitman, GA, Fuller, J, Neil, A, Sacks, F, Moye, L, Pfeffer, M, Hawkins, CM, Wedel, H, Wikstrand, J, Krane, V, Tavazzi, L, Maggioni, A, Marchioli, R, Tognoni, G, Franzosi, MG, Bowman, L, Landray, MJ, Parish, S, Peto, R, Sleight, P, Ridker, PM, Macmahon, S, Marschner, I, Shaw, J, Serruys, PW, Nakamura, H, Knatterud, G, Furberg, C, Byington, R, Sattar, N, and Jukema, JW
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medicine.medical_specialty ,Statin ,medicine.drug_class ,Atorvastatin ,030204 cardiovascular system & hematology ,ATORVASTATIN ,PURLs® ,Rate ratio ,Article ,03 medical and health sciences ,0302 clinical medicine ,Medicine, General & Internal ,Risk Factors ,Internal medicine ,General & Internal Medicine ,medicine ,Humans ,Rosuvastatin ,CORONARY-HEART-DISEASE ,030212 general & internal medicine ,Myocardial infarction ,ROSUVASTATIN ,Stroke ,ELDERLY-PATIENTS ,Aged ,Randomized Controlled Trials as Topic ,Aged, 80 and over ,RISK ,Science & Technology ,Cholesterol Treatment Trialists' Collaboration ,Vascular disease ,business.industry ,CHOLESTEROL ,Age Factors ,General Medicine ,11 Medical And Health Sciences ,medicine.disease ,R1 ,3. Good health ,LOWERING THERAPY ,Regimen ,MYOCARDIAL-INFARCTION ,Cardiovascular Diseases ,CARDIOVASCULAR-DISEASE ,Hydroxymethylglutaryl-CoA Reductase Inhibitors ,business ,PRIMARY PREVENTION ,Life Sciences & Biomedicine ,medicine.drug - Abstract
Background: Statin therapy has been shown to reduce major vascular events and vascular mortality in a wide range of individuals, but there is uncertainty about its efficacy and safety among older people. We undertook a meta-analysis of data from all large statin trials to compare the effects of statin therapy at different ages.Methods: In this meta-analysis, randomised trials of statin therapy were eligible if they aimed to recruit at least 1000 participants with a scheduled treatment duration of at least 2 years. We analysed individual participant data from 22 trials (n=134 537) and detailed summary data from one trial (n=12 705) of statin therapy versus control, plus individual participant data from five trials of more intensive versus less intensive statin therapy (n=39 612). We subdivided participants into six age groups (55 years or younger, 56–60 years, 61–65 years, 66–70 years, 71–75 years, and older than 75 years). We estimated effects on major vascular events (ie, major coronary events, strokes, and coronary revascularisations), cause-specific mortality, and cancer incidence as the rate ratio (RR) per 1·0 mmol/L reduction in LDL cholesterol. We compared proportional risk reductions in different age subgroups by use of standard χ2 tests for heterogeneity when there were two groups, or trend when there were more than two groups.Findings: 14 483 (8%) of 186 854 participants in the 28 trials were older than 75 years at randomisation, and the median follow-up duration was 4·9 years. Overall, statin therapy or a more intensive statin regimen produced a 21% (RR 0·79, 95% CI 0·77–0·81) proportional reduction in major vascular events per 1·0 mmol/L reduction in LDL cholesterol. We observed a significant reduction in major vascular events in all age groups. Although proportional reductions in major vascular events diminished slightly with age, this trend was not statistically significant (ptrend=0·06). Overall, statin or more intensive therapy yielded a 24% (RR 0·76, 95% CI 0·73–0·79) proportional reduction in major coronary events per 1·0 mmol/L reduction in LDL cholesterol, and with increasing age, we observed a trend towards smaller proportional risk reductions in major coronary events (ptrend=0·009). We observed a 25% (RR 0·75, 95% CI 0·73–0·78) proportional reduction in the risk of coronary revascularisation procedures with statin therapy or a more intensive statin regimen per 1·0 mmol/L lower LDL cholesterol, which did not differ significantly across age groups (ptrend=0·6). Similarly, the proportional reductions in stroke of any type (RR 0·84, 95% CI 0·80–0·89) did not differ significantly across age groups (ptrend=0·7). After exclusion of four trials which enrolled only patients with heart failure or undergoing renal dialysis (among whom statin therapy has not been shown to be effective), the trend to smaller proportional risk reductions with increasing age persisted for major coronary events (ptrend=0·01), and remained non-significant for major vascular events (ptrend=0·3). The proportional reduction in major vascular events was similar, irrespective of age, among patients with pre-existing vascular disease (ptrend=0·2), but appeared smaller among older than among younger individuals not known to have vascular disease (ptrend=0·05). We found a 12% (RR 0·88, 95% CI 0·85–0·91) proportional reduction in vascular mortality per 1·0 mmol/L reduction in LDL cholesterol, with a trend towards smaller proportional reductions with older age (ptrend=0·004), but this trend did not persist after exclusion of the heart failure or dialysis trials (ptrend=0·2). Statin therapy had no effect at any age on non-vascular mortality, cancer death, or cancer incidence.Interpretation: Statin therapy produces significant reductions in major vascular events irrespective of age, but there is less direct evidence of benefit among patients older than 75 years who do not already have evidence of occlusive vascular disease. This limitation is now being addressed by further trials.Funding: Australian National Health and Medical Research Council, National Institute for Health Research Oxford Biomedical Research Centre, UK Medical Research Council, and British Heart Foundation.
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- 2019
29. Recent trials of lipid lowering
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Ray, K. K., Cannon, C. P., and Braunwald, E.
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- 2007
30. Personal reflections on fibrinolytic therapy of acute myocardial infarction
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BRAUNWALD, E.
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- 2006
31. Chairmen's summary
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BRAUNWALD, E and GURFINKEL, E
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- 1999
32. Advances in unstable angina: the role of low molecular weight heparins
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BRAUNWALD, E and GURFINKEL, E
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- 1999
33. Management of unstable angina based on considerations of aetiology
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Braunwald, E
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- 1999
34. Reduction in Subtypes and Sizes of Myocardial Infarction With Ticagrelor in PEGASUS-TIMI 54
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Bonaca, M.P., Wiviott, S.D., Morrow, D.A., Steg, P.G., Hamm, C., Bhatt, D.L., Storey, R.F., Cohen, M., Kuder , J., Im, K., Magnani, G., Budaj, A., Nicolau, J.C., Parkhomenko, A., Lopez-Sendon, J., Dellborg, M., Diaz, R., Van de Werf, F., Corbalan, R., Goudev, A., Jensen, E.C., Johanson, P., Braunwald, E., and Sabatine, M.S.
- Abstract
Background: Ticagrelor reduced cardiovascular death, myocardial infarction (MI), or stroke in patients with prior MI in PEGASUSTIMI 54 (Prevention of Cardiovascular Events [eg, Death From Heart or Vascular Disease, Heart Attack, or Stroke] in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin). MI can occur in diverse settings and with varying severity; therefore, understanding the types and sizes of MI events prevented is of clinical importance.\ud Methods and Results: MIs were adjudicated by a blinded clinical events committee and categorized by subtype and fold elevation of peak cardiac troponin over the upper limit of normal. A total of 1042 MIs occurred in 898 of the 21 162 randomized patients over a median follow-up of 33 months. The majority of the MIs (76%) were spontaneous (Type 1), with demand MI (Type 2) and stent thrombosis (Type 4b) accounting for 13% and 9%, respectively; sudden death (Type 3), percutaneous coronary intervention–related (Type 4a) and coronary artery bypass graft–related (Type 5) each accounted for
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- 2018
35. 460Edoxaban versus warfarin in atrial fibrillation patients with low, mid and high body weight: analysis of outcomes in the engage AF TIMI 48 trial
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Boriani, G, primary, Ruff, C T, additional, Kuder, J F, additional, Shi, M, additional, Lanz, H, additional, Antman, E M, additional, Braunwald, E, additional, and Giugliano, R P, additional
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- 2019
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36. P3526Heart Failure hospitalization and mortality in non-valvular Atrial Fibrillation: The ENGAGE-AF TIMI 48 Trial
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Inciardi, R M, primary, Giugliano, R, additional, Nordio, F, additional, Ruff, C, additional, Antman, E, additional, Rutman, H, additional, Braunwald, E, additional, and Solomon, S D, additional
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- 2019
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37. 410Heart failure risk stratification and efficacy of dapagliflozin in patients with type 2 diabetes mellitus
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Berg, D, primary, Wiviott, S, additional, Scirica, B, additional, Gurmu, Y, additional, Mosenzon, O, additional, Murphy, S, additional, Bhatt, D, additional, Leiter, L, additional, McGuire, D, additional, Wilding, J, additional, Johansson, P, additional, Langkilde, A, additional, Raz, I, additional, Braunwald, E, additional, and Sabatine, M, additional
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- 2019
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38. P4606Comparing biomarker profiles in patients with stable atherosclerosis treated with anacetrapib versus placebo: a nested proteomic study from HPS3/TIMI 55-REVEAL
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Berg, D, primary, Morrow, D, additional, and Braunwald, E, additional
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- 2019
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39. 4331Safety and efficacy of sacubitril/valsartan by dose level in patients hospitalized with acute heart failure: Observations from PIONEER-HF
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Morrow, D A, primary, Velazquez, E J, additional, Devore, A D, additional, Duffy, C I, additional, Gurmu, Y, additional, McCague, K, additional, Rocha, R, additional, and Braunwald, E, additional
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- 2019
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40. 1135Angiotensin receptor-neprilysin inhibition in patients with de novo acute decompensated heart failure: a prespecified subgroup analysis of the PIONEER-HF trial
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Ambrosy, A, primary, Braunwald, E, additional, Morrow, D, additional, Devore, A, additional, McCague, K, additional, Duffy, C, additional, Rocha, R, additional, and Velazquez, E, additional
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- 2019
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41. Edoxaban versus warfarin in patients with atrial fibrillation
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Robert P. Giugliano, Christian T. Ruff, Eugene Braunwald, Sabina A. Murphy, Stephen D. Wiviott, Jonathan L. Halperin, Albert L. Waldo, Michael D. Ezekowitz, Jeffrey I. Weitz, Jind?ich ?pinar, Witold Ruzyllo, Mikhail Ruda, Yukihiro Koretsune, Joshua Betcher, Minggao Shi, Laura T. Grip, Shirali P. Patel, Indravadan Patel, James J. Hanyok, Michele Mercuri, Elliott M. Antman, Braunwald E, Antman EM, Giugliano RP, Ruff CT, Morin SE, Hoffman EB, Murphy SA, Deenadayalu N, Grip L, Mercuri M, Lanz H, Patel I, Curt V, Duggal A, Hanyok J, Davé J, Morgan D, Choi Y, Shi M, Jin J, Xie J, Crerand W, Kappelhof J, Maxwell W, Skinner M, Patel S, Betcher J, Selicato G, Otto C. Jr, Reissner C, Smith K, Ostroske J, Ron A, Giugliano R, Connolly S, Camm J, Ezekowitz M, Halperin J, Waldo A, Paolasso E, Aylward P, Heidbuchel H, Nicolau JC, Goudev A, Roy D, Weitz J, Corbalán R, Yang Y, Botero R, Bergovec M, Ŝpinar J, Grande P, Hassager C, Voitk J, Huikuri H, Nieminen M, Blanc JJ, LeHeuzey JY, Mitrovic V, Alexopoulos D, Sotomora G, Kiss R, SomaRaju B, Lewis B, Merlini P, Metra M, Koretsune Y, Yamashita T, García Castillo A, Ophuis T, White H, Atar D, Horna M, Babilonia N, Ruzyllo W, Morais J, Dorobantu M, Ruda M, Ostojic M, Duris T, Dalby A, Chung N, Zamorano JL, Juul Möller S, Moccetti T, Chen SA, Sritara P, Oto A, Parkhomenko A, Senior R, Verheugt F, Skene A, Anderson J, Bauer K, Easton JD, Goto S, Wiviott S, Lowe C, Awtry E, Berger CJ, Croce K, Desai A, Gelfand E, Goessling W, Greenberger NJ, Ho C, Leeman DE, Link MS, Norden AD, Pande A, Rost N, Ruberg F, Silverman S, Singhal A, Vita JA, Vogelmann O, Gonzalez C, Ahuad Guerrero R, Rodriguez M, Albisu J, Rosales E, Allall O, Reguero M, Alvarez C, Garcia M, Ameriso S, Ameriso P, Amuchastegui M, Caceres M, Beloscar J, Petrucci J, Berli M, Budassi N, Valle M, Bustamante Labarta G, Saravia M, Caccavo A, Fracaro V, Cartasegna L, Novas V, Caruso O, Zarandon RS, Colombo H, Morandini M, Cuello J, Rosell M, Cuneo C, Bocanera M, D'Amico A, Cendali G, Dran R, Moreno V, Estol C, Davolos M, Facello A, Facello M, Falu E, Iriarte M, Femenia F, Arrieta M, Fuselli J, Zanotti A, Gant Lopez J, Meiller F, Garcia Duran R, Perlo D, Garrido M, Ceirano C, Giacomi G, Eden M, Giannaula R, Huerta M, Goicoechea R, von Wulffen M, Hominal M, Bianchini M, Jure H, Jure D, Kevorkian R, Monaco F, Lanternier G, Belcuore M, Liniado G, Iglesias M, Litvak B, Nigro A, Llanos J, Vignau S, Lorente C, Shatsky K, Lotti J, Raimondi G, Mackinnon I, Carne M, Manuale O, Calderon M, Marino J, Funes I, Muntaner J, Gandur H, Nul D, Verdini E, Piskorz D, Tommasi A, Povedano G, Casares E, Pozzer D, Fernandez E, Prado A, Venturini C, Ramos H, Navarrete S, Alvarez M, Sanchez A, Bowen L, Sanjurjo M, Codutti O, Saravia Toledo S, Formoso I, Schmidberg J, Goloboulicz A, Schygiel P, Buzzetti C, Severino P, Morara P, Sosa Liprandi M, Teves M, Vico M, Morell Y, Anderson C, Paraskevaidis T, Arstall M, Hoffmann B, Colquhoun D, Price Smith S, Crimmins D, Slattery A, Dart A, Kay S, Davis S, Silver G, Flecknoe Brown S, Roberts J, Gates P, Jones S, Lehman R, Morrison H, McKeirnan M, Li J, Paul V, Batta C, Purnell P, Perrett L, Szto G, O'Shea V, Capiau L, Banaeian F, De Bleecker J, de Koning K, De Tollenaere M, De Bruyne L, Desfontaines P, Tincani G, Meeusen K, Herzet J, Malmendier D, Mairesse G, Raepers M, Parqué J, Clinckemaille N, Scavée C, Huyberechts D, Stockman D, Jacobs C, Vandekerckhove Y, Derycker K, Vanwelden J, van Welden J, Vervoort G, Mestdagh I, Vrolix M, Beerts C, Wollaert B, Denie D, Amato Vincenzo de Paola A, Coutinho E, Andrade Lotufo P, de Melo RF, Atie J, Motta C, Augusto Alves da Costa F, Ferraz RF, Bertolim Precoma D, Sehnem E, Botelho R, Cunha S, Brondani R, Fleck N, Chaves Junior H, Silva J, Costantini C, Barroso D, De Patta M, Pereira V, Duda N, Laimer R, Dutra O, Morgado S, Faustino Saporito W, Seroqui M, Ferreira L, Araújo E, Finimundi H, Daitz C, Gagliardi R, Pereira G, Gomes M, Gomes A, Guimarães A, Ninho L, Jaeger C, Pereira L, Jorge J, Cury C, Kaiser S, Almeida A, Kalil C, Radaelli G, Kunz Sebba Barroso de Souza W, Morales K, Leaes P, Luiz RO, Pimenta Almeida J, Gozalo A, Reis G, Avellar K, Reis Katz Weiand L, Leipelt J, Rocha J, Barros R, Rodrigues L, Rocha MR, Rodrigues A, Rodrigues D, Rossi dos Santos F, Pagnan LG, Sampaio R, do Val R, Saraiva J, Vicente C, Simoes M, Carraro A, Sobral Filho D, Lustosa E, Villas Boas F, Almeida M, Zimmermann S, Zimmermann EB, Chompalova B, Parishev G, Denchev S, Milcheva N, Donova T, Gergova V, Georgiev B, Kostova E, Kinova E, Hergeldjieva V, Kamenova P, Manolova A, Vasilev I, Mihov A, Miteva B, Mincheva V, Stoyanovski V, Nikolov F, Vasilev D, Pencheva G, Kostov K, Petranov S, Milusheva T, Popov A, Staneva A, Momchilova Lozeva D, Todorov G, Nyagina M, Tumbev H, Tumbeva D, Tzekova M, Kitova M, Manoylov E, Archibald J, Antle S, Bhargava R, Stafford C, Bose S, Hundseth M, Cha J, Otis J, Chehayeb R, Lepage C, Chilvers M, Vansickle L, Cleveland D, Valley S, Constance C, Gauthier M, Costi P, Masson C, Coutu B, Denis I, du Preez M, Kubanska A, Dufresne M, Krider J, Eikelboom J, Zondag M, Fortin C, Viau C, Green M, Houbraken D, Hatheway R, Mabee J, Heath J, Scott L, Ho K, Ho V, Hoag G, Standring R, Huynh T, Perkins L, Kouz S, Roy M, Labonte R, Dewar C, Lainesse A, St Germain L, Lam S, Lam H, Lichtenstein T, Roberts P, Luton R, Douglas S, Ma P, Seib M, MacCallum C, Matthews J, Malette P, Vaillancourt T, Maranda C, Studenikow E, Mawji A, Morely A, Morrison D, Roth M, Mucha M, Najarali A, Lamoureux U, Nicholson R, O'Hara G, Banville P, O'Mahony W, Bolton R, Parkash R, Carroll L, Pesant Y, Sardin V, Polasek P, Turri L, Qureshi A, Nethercott C, Ricci J, Bozek B, Rupka D, Marchand C, Shu D, Silverio G, St Hilaire R, Morissette A, Sussman J, Kailey P, Syan G, Bobbie C, Talajic M, David D, Talbot P, Tremblay M, Teitelbaum I, Teitelbaum J, Velthuysen G, Giesbrecht L, Wahby R, Morley A, Wharton S, Caterini T, Woodford T, Balboa W, Matus LR, Bugueño C, Mondaca PM, Cobos J, Obreque C, Corbalan R, Parada A, Florenzano F, Diaz PA, Lopetegui M, Rebolledo C, Manriquez L, Silva LM, Martinez D, Llamas RR, Opazo M, Pérez MC, Pincetti C, Carrasco GT, Potthoff S, Staub JZ, Campisto Y, Stockins B, Lara CL, Yovaniniz P, Azua MG, Bai F, Xu GL, Chen JZ, Xie XD, Chen XP, Zhang X, Dong YG, Feng C, Fu GS, Zhang P, Hong K, You ZG, Hong L, Qiu Y, Jiang XJ, Qu Z, Li L, Liu H, Li TF, Kong YQ, Li WM, Liu B, Li ZQ, Liu Y, Liao DN, Gu XJ, Liu L, Lu ZH, Ma SM, Yang ZY, Wang DM, Qi SY, Wang GP, Shi XJ, Wei M, Huang D, Wu SL, Li YE, Xu JH, Gu JY, Xu YM, Liang YZ, Yang K, Li AY, Yang YJ, Zheng X, Zheng Y, Gao M, Yin YH, Xu YP, Yu B, Li LL, Yuan ZY, Qiang H, Zhang HQ, Lin YN, Zhang Z, Kang H, Zhao RP, Han RJ, Zhao XL, Wang JQ, Zheng ZQ, Li BG, Zhou SX, Zhang YL, Accini J, Accini M, Cano N, Pineda LL, Delgado Restrepo J, Arroyave C, Fernández Ruiz R, Diaz IA, Hernandez H, Delgado P, Jaramillo Muñoz C, Builes A, Manzur F, Rodriguez ER, Moncada Corredor M, Giraldo DL, Orozco Linares L, Fonseca J, Quintero A, Gonzales C, Sanchez Vallejo G, Mejia IP, Bagatin J, Carevic V, Car S, Jeric M, Ciglenecki N, Tusek S, Ferri Certic J, Romic I, Francetic I, Ausperger KM, Jelic V, Jurinjak SJ, Knezevic A, Buksa B, Samardzic P, Lukenda KC, Steiner R, Kirner D, Sutalo K, Bakliza Z, Vrazic H, Lucijanic T, Bar M, Brodova P, Berka L, Kunkelova V, Brtko M, Burianova H, Cermak O, Elbl L, Ferkl R, Florian J, Francek L, Golan L, Gregor P, Honkova M, Hubac J, Jandik J, Jarkovsky P, Jelinek Z, Jerabek O, Jirmar R, Kobza R, Kochrt M, Kostkova G, Kosek Z, Kovar P, Kuchar R, Kvasnicka J, Ludka O, Machova V, Krocova E, Melichar M, Nechanicky R, Olsr J, Peterka K, Petrova I, Havlova I, Pisova J, Podrazil P, Jirsova E, Reichert P, Slaby J, Spacek R, Spinar J, Labrova R, Vodnansky P, Samkova D, Zidkova E, Dodt K, Christensen H, Christensen L, Loof A, Ibsen H, Madsen H, Iversen H, Veng Olsen T, Nielsen H, Olsen R, Overgaard K, Petrovic V, Raymond I, Raae D, Sand N, Svenningsen A, Torp Pedersen C, Jakobsen U, Wiggers H, Serup Hansen K, Kaik J, Stern A, Kolk R, Laane E, Rivis L, Paumets M, Laheäär M, Rosenthal A, Rajasalu R, Vahula V, Ratnik E, Kaarleenkaski S, Hussi E, Valpas S, Jäkälä P, Lappalainen T, Mäenpää A, Viitaniemi J, Nyman K, Sankari T, Rasi H, Salminen O, Virtanen V, Nappila H, Le Heuzey J, Agraou B, El Jarroudi F, Amarenco P, Boursin P, Babuty D, Boyer M, Belhassane A, Berbari H, Blanc J, Dias P, Coisne D, Berger N, Decoulx E, El Jarroudi M, Dinanian S, Arfaoui M, Hermida J, Deruche E, Kacet S, Corbut S, Poulard J, Leparree S, Roudaut R, Duprat C, Al Zoebi A, Wurow A, Bernhardt P, Dichristin U, Berrouschot J, Vierbeck S, Beyer Westendorf J, Sehr B, Bouzo M, Schnelzer P, Braun R, Ladenburger K, Buhr M, Weihrauch D, Contzen C, Kara M, Daut W, Ayasse D, Degtyareva E, Kranz P, Drescher T, Herfurth B, Faghih M, Forck Boedeker K, Schneider K, Fuchs R, Manuela W, Grigat C, Otto A, Hartmann A, Peitz M, Heuer H, Dieckheuer U, Hoffmann U, Dorn S, Hoffmann S, Schuppe M, Horacek T, Fink P, Junggeburth J, Schmid S, Jungmair W, Schoen B, Kleinecke Pohl U, Meusel P, Koenig H, Bauch F, Lohrbaecher Kozak I, Grosse B, Lueders S, Venneklaas U, Luttermann M, Wulf M, Maus O, Hoefer K, Meissner G, Braemer U, Meyer Pannwitt U, Frahm E, Vogt S, Muegge A, Barbera S, Mueller Glamann M, Raddatz K, Piechatzek R, Lewinsky D, Pohl W, Proskynitopoulos N, Kuhlmann M, Rack K, Pilipenko H, Rinke A, Kühlenborg A, Schaefer A, Szymanowski N, Schellong S, Frommhold R, Schenkenberger I, Finsterbusch T, Dreykluft K, Schiewe C, Schmidt A, Schmidt M, Schreckenberg A, Hellmers J, Seibert H, Gold G, Sohn H, Baylacher M, Spitzer S, Bonin K, Stoehring R, Taggeselle J, Zarpentin C, Veltkamp R, Ludwig I, Voehringer, Buchholz M, Weyland K, Winkelmann B, Buelow Johansen B, Wolde C, Winter K, Mavronasiou E, Bourlios P, Tziortziotis A, Karamitsos C, Exarchou E, Kifnidis K, Daskalaki A, Moschos N, Dimitra K, Olympios C, Kartsagkoulis E, Pyrgakis V, Korantanis K, Ayau Milla O, Ramirez Vde L, Guzman Melgar I, Jimenez T, Ovando Lavagnino A, Guevara S, Rodas Estrada M, Sanchez M, Pozuelos JM, Sanchez Samayoa C, Guerra L, Velasquez Camas L, Almaraz SP, Dioszeghy P, Muskoczki E, Edes I, Szatmari J, Fiok J, Varga A, Kanakaridisz N, Kosztyu M, Kis E, Feil JF, Jakal A, Koczka M, Kovacs I, Baranyai M, Kovacs Z, Lupkovics G, Karakai HH, Matoltsy A, Kiss T, Medvegy M, Kiss K, Merkely B, Kolumban E, Nagy A, Palinkas A, Toth SR, Sayour A, Bognar A, Simor T, Ruzsa D, Sipos T, Szakal I, Tomcsanyi J, Marosi A, Vertes A, Kincses M, Malhan S, Abdullakutty J, Agarwal D, Ranka R, Arneja J, Memon A, Arora V, Shree R, Avvaru G, Shaikh A, Babu P, Rao B, Babu R, Reddy J, Banker D, Sheth T, Benjarge P, Surushe S, Bharani A, Solanki R, Bhargava V, Rathi A, Biniwale A, Bhuti M, Calambur N, Somaraju B, Karnwal N, Chopda M, Mali N, Goyal N, Saini A, Gupta J, Singh P, Hadan S, Savanth P, Hardas S, Thakor G, Hiremath J, Ghume A, Jain R, Pahuja M, Joseph S, Oommen D, Joseph J, Thomas R, Joshi H, Iby, Kale V, Raut N, Kandekar B, Kandekar S, Kishore R, Krishnan H, Kotiwale V, Kulkarni R, Deokar M, Kulkarni G, Lawande A, Kumar P, Karpuram M, Kumar A, Francis J, Kumbla M, Anthony A, Lavhe P, Kale M, Mardikar H, Bhaskarwar P, Mathur A, Sharma P, Menon J, Francis V, Namjoshi D, Shelke S, Narendra J, Natarajan S, Oomaan A, Gurusamy P, Angel J, Purayil MP, Shams S, Pandurangi U, Sababathi R, Parekh P, Jasani B, Patki N, Babbar A, Pinto B, Kharalkar H, Premchand R, Jambula H, Rao M, Vuriya A, Ravi Shankar A, Reddy R, Bekal S, Barai A, Saha D, Gadepalli R, Sant H, Jadhav D, Sarna M, Arora T, Sawhney J, Singh R, Sethi K, Bansal N, Sethia A, Sethia S, Shetty G, Sudheer R, Singh G, Gupta R, Srinivas A, Thankaraj L, Varma S, Kaur A, Vinod MV, Thakur B, Zanwar I, Dharmarao A, Atar S, Lasri E, Dicker D, Marcoviciu D, Elias M, Ron GA, Francis A, Ghantous R, Goldhaber A, Goldhaber M, Gottlieb S, Rouwaida S, Grossman E, Dagan T, Hasin Y, Roshrosh M, Hayek T, Majdoub A, Klainman E, Genin I, Lahav M, Gilat T, Ben Ari M, Lishner M, Karny M, Ouzan E, Givoni H, Rozenman Y, Logvinenko S, Schiff E, Sterlin J, Shochat M, Aloni I, Swissa M, Belatsky V, Tsalihin D, Kisos D, Zeltser D, Platner N, Berni A, Giovannelli F, Boriani G, Cervi E, Comi G, Peruzzotti L, Cuccia C, Forgione C, De Caterina R, De Pace D, De Servi S, Mariani M, Di Lenarda A, Mazzone C, Di Pasquale G, Di Niro M, Fattore L, Bosco B, Grassia V, Murena E, Laffi, Gaggioli G, Lo Pinto G, Raggi F, Marino P, Francalacci G, Babbolin M, Bulgari M, Penco M, Lioy E, Marciano C, Pirelli S, Paradiso G, Piseddu G, Fenu L, Raisaro A, Granzow K, Rasura M, Cannoni S, Severi S, Breschi M, Toschi V, Gagliano M, Zacà V, Furiozzi F, Hirahara T, Akihisa U, Masaki W, Ajioka M, Matsushita C, Anzai T, Mino K, Arakawa S, Tsukimine A, Endo H, Fujiwara M, Fujii K, Kozeni S, Fujii E, Kotera M, Fujimoto S, Omae K, Fujimoto K, Ichishita Y, Fujita T, Ito Y, Fukamizu S, Harada J, Fukuda N, Fujimoto C, Funazaki T, Yamaguchi A, Furukawa Y, Kamitake C, Hagiwara N, Naganuma M, Hara S, Kumagai S, Harada K, Fuki Y, Haruna T, Nakahara Y, Hashimoto Y, Shimazu Y, Hiasa Y, Oga Y, Higashikata T, Nakagawa Y, Hirayama A, Kawaguchi A, Iesaka Y, Miyamoto C, Iijima T, Higuchi K, Ino H, Noguchi H, Inomata T, Nakamura K, Ishibashi Y, Nozaki T, Ishii Y, Tomita H, Ishimaru S, Ise M, Itamoto K, Ito T, Onishi M, Iwade K, Sakuma Y, Iwasaki T, Nagatome H, Kakinoki S, Adachi C, Kamakura S, Nakahara F, Kamijo M, Iida S, Kamiyama K, Fujii R, Kato K, Ishida A, Kazatani Y, Ichikawa Y, Kitazawa H, Igarashi C, Kobayashi Y, Kikuchi R, Kohno M, Tamura S, Yumoto I, Kurabayashi M, Koya E, Masuyama T, Kaneno Y, Matsuda K, Ebina E, Meno H, Satake M, Mita T, Takeda M, Miyamoto N, Kimizu T, Miyauchi Y, Sakamoto S, Munemasa M, Murata J, Nagai Y, Sakata Y, Naito S, Oyama H, Nishi Y, Nagase T, Ochiai J, Junko H, Ogawa T, Sugeno M, Oguro H, Tanabe M, Okada K, Moriyama Y, Okajima K, Nakashima M, Okazaki O, Wada H, Okishige K, Kitani S, Okumura K, Narita Y, Onaka H, Moriyama H, Ozaki Y, Tanikawa I, Sakagami S, Nakano A, Sakuragi S, Hayashi N, Sakurai S, Ooki H, Sasaki T, Oosawa N, Satoh A, Fujimoto E, Seino Y, Narumi M, Shirai T, Shigenari M, Shoji Y, Ueda J, Sugi K, Miyazaki E, Sumii K, Asakura H, Takagi M, Mohri S, Takahashi W, Yoshida K, Takahashi A, Kishi N, Takahashi T, Sakurai Y, Takeda K, Yahata A, Takenaka T, Yamagishi K, Takeuchi S, Watanabe E, Tanaka K, Uchida M, Tanouchi J, Nishiya Y, Tsuboi H, Tsuboi N, Terakura K, Uematsu M, Yasumoto S, Ueyama Y, Usuda K, Sakai Y, Yagi M, Sato A, Yagi H, Kuroda T, Yamabe H, Sakamoto Y, Yamada T, Yamano R, Yamagishi T, Sasaki S, Yamamoto Y, Yamashina A, Takiguchi M, Yonehara T, Yoshino H, Nomura H, Yoshioka K, Fujiwara Y, Bayram Llamas E, Hurtado A, Calvo Vargas C, Limon MC, Cardona Muñoz E, Hernandez S, Carrillo J, Delgadillo T, Cásares Ramirez M, Valles JF, Garcia N, Colin MA, Garcia Castillo A, Jaramillo A, Leiva Pons J, de la Mora S, Llamas Esperón G, Grajales A, Mendez Machado G, Avila H, Ruiz LN, Magallanes G, Sánchez Díaz C, Ortiz A, Sánchez RV, Velazquez EM, Alhakim M, van Welsen I, Bruning T, Jones A, Buiks C, de Groot J, Radder I, de Vos R, Hazeleger R, Daniels R, Kietselaer B, Muijs L, Mannaerts H, Kooiman E, Mevissen H, van der Heijden D, Hofmeyer H, Anscombe R, O'Meeghan T, Kjentjes M, Benatar J, Borthwick L, Doughty R, Copley M, Fisher R, Monkley R, Green B, Scott D, Hamer A, Tomlinson J, Hart H, Turner A, Cammell R, Troughton R, Skelton L, Young C, Kennett K, Claussen H, Hofsøy K, Melbue R, Sandvik J, Thunhaug H, Tveit A, Enger S, Bustamante G, Guillen MT, Cabrera J, Mendoza RE, Chavez C, Luna C, Lema J, Carrion A, Llerena N, Bedregal SA, Medina Palomino F, Rodriguez J, Minchola J, Bautista C, Negron Miguel S, Armas BH, Rodriguez A, Romero N, Torres P, Rodriguez KF, Yanac Chavez P, Delgado S, Sambaz CM, Barcinas R, Zapanta M, Coching R, Vallenas M, Matiga G, Enad C, Rogelio G, Joaquin F, Roxas A. Jr, Gilo L, To R, Aquino M, Villamor L, Nario K, Adamus J, Korzeniowska Adamus J, Baszak J, Bronisz M, Cieslak B, Busz Papiez B, Krzystolik A, Cymerman K, Dabrowska M, Ptak A, Derlaga B, Laskowska Derlaga E, Domanska E, Guziewicz M, Gieroba A, Zajac E, Gniot J, Mroczkowski P, Januszewicz A, Makowiecka Ciesla M, Jazwinska Tarnawska E, Ciezak P, Jurowiecki J, Kaczmarek B, Pacholska A, Kaminski L, Kania G, Tymendorf K, Karczmarczyk A, Kaliszczak R, Konieczny M, Benicka E, Korzeniak R, Borowski W, Krzyzanowski W, Muzyk Osikowicz M, Kus W, Lesnik J, Wierzykowski T, Lewczuk J, Stopyra Poczatek M, Lubinski A, Szymanska K, Lysek R, Jaguszewska G, Matyszczak Toniak L, Sznajder R, Wnetrzak Michalska R, Kosmaczewska A, Mazur S, Chmielowski A, Miekus P, Kosmalska K, Mosiewicz J, Myslinski W, Napora P, Biniek D, Nessler J, Nessler B, Niezgoda K, Nej A, Nowak J, Olszewski M, Podjacka D, Janczewska D, Pogorzelska H, Polaszewska Pulkownik V, Bojanowska E, Raczak G, Zienciuk Krajka A, Rewinska H, Rozmyslowicz Szerminska W, Ronkowski R, Norwa Otto B, Sendrowski D, Spyra J, Szolkiewicz M, Malanska A, Turbak R, Wrobel W, Muzalewski P, Wysokinski A, Kudlicki J, Zarebinski M, Krauze R, Zielinski M, Nawrot M, Matias F, Correia J, Gil V, Lopes S, Madeira J, Maymone D, Martins D, Neves E, Monteiro P, Oliveira D, Marques AL, Castro C, Salgado A, Gonçalves A, Sao Marcos H, Santos O, Nunes LV, Sao Teotonio H, Santos J, Soares D, Albulescu P, Ciortea M, Apetrei E, Matei C, Bartos D, Badila E, Bengus C, Ochean V, Bobescu E, Doka B, Bolohan F, Ciobotaru G, Andor M, Coman I, Ghionea M, Constantinescu M, Creteanu M, Parasteac M, Cristea M, Anciu M, Crisu D, Jemna D, Dobre I, Voicu O, Dobreanu D, Sirbu I, Dragomir D, Jurca S, Iosipescu L, Costache L, Minescu B, Serban D, Pop C, Cozma M, Popescu M, Ardelean A, Sipciu D, Plosca P, Stamate S, Spinu C, Topolnitchi L, Topolnitchi O, Tudoran M, Tudoran C, Zhukova N, Arutyunov G, Chernyavskaya T, Ballyuzek M, Alexandrova L, Barbarash O, Bashkireva A, Bart B, Larina V, Belenky D, Kosolapov Y, Berns S, Yukhno E, Bokarev I, Khlevchuk T, Chumakova G, Pokutneva O, Demko A, Masin A, Dovgalevsky P, Puchinyan N, Drapkina O, Zyatenkova E, Egorova L, Esip V, Kirichek N, Filatov A, Soin I, Gilinskaya O, Valuyshkih E, Glezer M, Valovyeva S, Golitsyn S, Kratskina T, Goloshchekin B, Laptev I, Gratsiansky N, Mazovets O, Karpov Y, Buza V, Kosenko B, Khirmanov V, Kireenkov I, Khokhlov A, Sinitsina O, Khokhlov R, Tsareva E, Khrustalev O, Khrustalev A, Kostenko V, Karabalieva S, Koziolova N, Polyanskaya E, Kozyrev O, Kostenko O, Kuznetsov V, Rychkov A, Lavrova O, Tereschenko L, Levashov S, Volkova E, Libis R, Maslova A, Libov I, Moiseeva Y, Lila A, Belousova L, Lukyanov Y, Lamden D, Nikolaev K, Nikolaev A, Nikolskaya I, Khromova O, Novikova N, Patrusheva S, Panchenko E, Laguta P, Panov A, Nilk R, Polkanova E, Matveeva I, Poluyanova N, Pikalova N, Raskina T, Letaeva M, Rebrov A, Karoli N, Repin M, Rodina N, Shaposhnik I, Lebedev E, Shogenov Z, Agirov M, Sidorenko B, Vorontsova S, Sinitsina I, Orlov V, Golshmid M, Sizova Z, Lapidus N, Sobolev K, Erofeeva S, Suprun E, Dronov D, Tarasov N, Isakov L, Tereshenko S, Kositsyna I, Tikhonova E, Solovyev A, Timofeev A, Bulygin S, Ustyugov S, Rossovskaya M, Vishnevsky A, Kirgizova A, Volkov D, Yakusevich V, Petrochenko A, Yakushin S, Nikulina N, Zateyshchikov D, Zotova I, Zateyshchikova A, Mankhaeva B, Zenin S, Kononenko O, Zubeeva G, Motylev I, Apostolovic S, Djordjevic Radojkovic D, Celic V, Majstorovic A, Cemerlic Adjic N, Bjelobrk M, Despotovic N, Erceg P, Ilic S, Ilic B, Krotin M, Djokovic A, Miloradovic V, Djokic I, Otasevic P, Tasic N, Potpara T, Polovina M, Putnikovic B, Kalezic T, Seferovic P, Milinkovic I, Tavciovski D, Davicevic Z, Vasiljevic Pokrajcic Z, Mitrovic P, Vujisic Tesic B, Tesic M, Ambrovicova V, Ambrovic I, Banikova A, Dukat A, Kosmalova V, Dulkova K, Dulka T, Vankova L, Dzupina A, Dzupinova M, Hatalova K, Hatala R, Hranai M, Hofmanova J, Kasperova V, Reptova A, Mazur J, Pella D, Fedacko J, Ruffini L, Morsky J, Slanina M, Kmec J, Zachar A, Kokles M, Zareczky P, Bollova D, Badenhorst J, Erasmus L, Basson M, Poynton M, Allman J, Ellis G, Botha L, Engelbrecht J, Mostert M, Essop M, Nunkoo T, Gani M, Wilson L, Kelfkens Y, Mitha I, Taljaard J, Naidoo D, Duki Y, Snyders F, Munnik M, Soma P, Johnston H, van der Merwe N, Goosen Y, van Zyl L, le Roux M, Venter T, Wessels L, Bae HJ, Han MG, Cha JK, Kim DH, Cho BR, Ryu DR, Choi HH, Hong KS, Chung WS, Oh YS, Han SH, Lee KH, Hong TJ, Lee HW, Hyon MS, Jung JW, Jeon HK, Lee JM, Kang DH, Choi KJ, Kim CJ, Jin ES, Kim DS, Seo JS, Kim HS, Cha MJ, Kim JT, Park MS, Kim JH, Park JH, Kim JS, Park SJ, Kim SH, Seo JB, Kim YJ, Chun MY, Lee MH, Joung BY, Lee SH, Shin DG, Namgung J, Kwak JJ, Rha SW, Na JO, Rim SJ, Kim JY, Arcocha Torres M, Rey AM, Blanco Coronado J, Puertas I, Bruguera Cortada J, Cabero P, Calvo C, Calvo G, de Arce Borda A, Asensio A, Diez Tejedor E, Guevara MP, Gonzalez Juanatey J, Moure M, Hernandez Madrid A, Delgado A, Lopez Garcia Aranda V, Barquero R, Manzano L, Abril SB, Merino J, Diaz Pintado M, Arias J, Fernandez M, Alvarez RF, Terns M, Delgado MD, Villuendas R, Astier L, Appelros P, Åkerberg A, Blom KB, Andersson R, Blomström P, Persson L, Carlsson T, Bengtsson AS, Dettmann S, Östberg S, Engdahl J, Karlsson L, Herlitz J, Winberg L, Jernhed H, Koskinen P, Håkansson E, Kozak P, Edlund M, Malmqvist L, Eriksson G, Randers F, Moodh J, Rautio A, Johansson M, Rönn F, Sundholm C, Stenberg A, Gunnarsson A, Thulin J, Broberg M, Slater IP, Cheng CC, Wu WS, Chiang CE, Yu WC, Chiang FT, Wu YW, Chiou CW, Yeh TC, Hsia CH, Chen YP, Huang JL, Chen YF, Kuo CT, Wang CL, Lai WT, Lin TH, Lee JT, Pai PY, Lin KH, Shyu KG, Chiu CZ, Tseng WK, Pan YF, Ueng KC, Lee SC, Wang JH, Tsai WC, Yeh HI, Kuo JY, Jirasirirojanakorn K, Pornchaiyasit K, Kaewsuwanna P, Sinthusopa W, Kiatchoosakun S, Sriprasert S, Laothavorn P, Bamrungpong P, Piyayotai D, Sripracha A, Panpunuan P, Sukonthasarn A, Mekara W, Vorasettakarnkij Y, Puripun E, Acikel M, Akilli H, Demir H, Ata N, Bayata S, Cakmak N, Calik A, Cayli M, Ceyhan C, Erdogan D, Ermis C, Kabul K, Kanadasi M, Turgut O, Tandogan I, Yalcin R, Yigit F, Yigit Z, Zoghi M, Batushkin V, Azhdari M, Bazylevych A, Vlasyuk Z, Bereznyakov I, Lebedynskaya M, Dotsenko S, Kulynych R, Dzyak G, Vasilyeva L, Faynyk A, Sorokivskyy M, Gavrysyuk V, Dzublik Y, Horbach L, Husyev V, Godlevska O, Samburg Y, Karpenko O, Nevolina I, Karpenko Y, Blihar O, Kaydashev I, Gerasimenko N, Kolomyyits S, Vasylets V, Kopytsya M, Petyunina O, Kotseruba V, Dvoieglazova M, Koval V, Ohirko O, Koval' O, Kaplan P, Kraiz I, Usan N, Kraydashenko O, Stets R, Kupnovytska I, Kyyak Y, Lizogub V, Gorna O, Malynovsky Y, Fedotov S, Ostrovska L, Ushakova Sokolova L, Dovgan N, Potapenko P, Nekrasa A, Prokhorov O, Leonidova V, Rebrov B, Gamachek O, Rishko M, Chendey T, Rudyk I, Shatilo V, Ishchuk V, Shcherbak V, Goncharova I, Shvetz N, Zamlynskyy M, Sirenko Y, Stanislavchuk M, Perebetiuk L, Sychov O, Lyzohub S, Tseluyko V, Kuznetsov I, Tykhonova S, Vakaliuk I, Drapchak I, Vatutin M, Sklyanna O, Vizir V, Goncharov O, Volkov V, Serik S, Yagensky A, Nahrebetskyy V, Yena L, Mudruk I, Zharinov O, Logvinov Y, Zhurba S, Shandra T, Aggarwal R, Smith S, Beeton I, Dunn S, Blagden M, Price R, Dougal K, Chapman O, Davies D, Choy A, Duff J, Cohen A, Wilmott R, D'Costa D, Douglas H, Dickinson D, Lie F, Ramasamy V, Lindsay S, Atkinson C, Linker N, Finlayson M, Lip G, Brown R, MacCallum P, Ebano P, MacLeod M, McGhee C, Marazzi P, Jones D, Maxwell T, Isted C, More R, Helliwell L, Moriarty A, Mackin A, Murdoch D, Andrews A, Newby D, Flint L, Pye M, Wright L, Avery D, Young G, Sopher M, Kennard S, Storey R, Bridge C, Turner W, Walker M, Venkataraman A, Gilchrist M, Watkin R, Chung A, Wright A, Wright J, Abi Mansour P, Panella M, Adams K, Lohman J, Adler J, Barash B, Adler P, Reiling S, Beck P, Ahmad A, Hussain A, Ahmadpour H, Lim G, Akhter F, Brubaker S, Alexander J, Genova Peeva E, Aliyar P, Godsey W, Allison J, Biscardi R, Almquist A, MacDonald H, Alsheikh T, Lane B, Amin K, Khetarpal S, Amin M, Persechino F, York T, Arnold T, Shoaf R, Arouni A, Rasmussen L, Attanti S, Strickland S, Aude Y, Cobos D, Awasty V, Baldwin E, Ayesu K, Thompson B, Baine S, Batista M, Baman R, Campbell G, Barber M, Altonen D, Barker T, Faircloth C, Barrington P, Gordon L, Bartkowiak A, Benton J, Beasley R, Hoffman T, Bedoya R, Luis Valdes M, Bedwell N, Craig M, Beinart S, Swaim D, Bensimhon D, Garman V, Berk M, Ibarra M, Bernard J, Eldred R, Bilal B, Preston S, Bilazarian S, Langone L, Bingham S, Antonino M, Block T, Talbot Lawson C, Blonder R, Ensminger E, Bloomberg R, Bloomberg K, Blue B, Vernon M, Borsheim M, Hickenbotham D, Bouchard A, Wade W, Bowden W, Ziegler K, Bradley A, Terry P, Brilakis E, Frey W, Brown H, Triano A, Bybee K, Al Maliky T, Cader C, Morton S, Canaday D, Canosa R, Hartranft E, Caplan J, Jameson L, Carr K, Phan D, Chang M, Hatfield G, Charlat M, Tamayo M, Chaturvedi S, Sawaya K, Ciaramita J, Bagby J, Clapp T, Clay A, McClelland M, Dutka C, Cohen R, Bossaers J, Colan D, Salpas S, Cole J, Fisher M, Concha M, Martinez E, Corbett B, Svadbik L, Cossu S, Mullinax K, Cottiero R, Masson E, Cowan L, Nelson L, Curtis B, Sarpola N, Dang N, Morgan T, Daniels S, Leka G, Datta S, Wulf A, Dave K, Dave B, Davuluri A, Ebreo N, De Lemos J, Debes C, Dean J, Warmack D, DeGarmo R, Carey J, Steward A, Desire A, Waters L, Devenport S, Briscoe C, Dhar S, Ucik S, DiGiovanna M, Tisdale L, Donovan D, Rodriguez L, Dotani I, Olson A, Drozdiak R, Habibi S, D'Souza A, Cullen T, Eade J, Dunn K, Eldadah Z, Quick R, Ellis J, Cristaldi J, Erenrich N, Johnson C, O'Brien J, Ettinger N, Shipp A, Everhart B, DeSalle D, Fahmy R, Watkins D, Feld L, Tameron A, Feldman J, Tang N, Felten W, Prior J, Fialkow J, Calvo M, Finkel M, Shriver D, Finkelstein S, Fischell T, Drew B, Fishbein G, Donahue S, Flores E, Slayton C, Forman S, Solis A, Frais M, Thrope C, Franco M, Gentry P, French W, Morales C, Friedlander I, Gaffney M, Jones J, Garb J, Miranda J, George F, Valentine H, Gerber J, Hinchion N, Gillespie E, Keane Richmond P, Gogia H, Ewing B, Goldscher D, Latteri J, Goldstein M, Gowda S, Rafala E, Graham S, Bonora M, Griffin S, Aull L, Griffin J, Goodman V, Grossman C, Davis A, Grove D, Mabe K, Guarino J, Gabela W, Guarnieri T, Guerrero, Foster B, Guthrie R, Felsman D, Gvora T, McLean R, Hack T, Morelli L, Hamroff G, Bentivenga L, Han M, Cavanna L, Harris J, Bobade M, Hearne S, Krater C, Heiman M, Dandekar U, Shah D, Henderson D, Millard D, Henry S, Harkins V, Hermany P, Batchell K, Herrod J, Miranda D, Herson S, Carey G, Hinchman D, Vieira P, Hippert R, Dutter S, Hoekstra J, Homan J, Homayouni A, Horton K, Sloss D, Hotchkiss D, Turner N, Houchin V, Howard V, Hays D, Howard L, Craft D, Huang P, Truva C, Hunter J, Battistelli E, Hurst P, Garza M, Hussain M, Tambawala M, Ison R, Butcher S, Jardula M, Andresen T, Johnson F, Phillips T, Jones R, Hughett G, Jovin I, Nichols M, Judson P, Royes A, Kahn B, Coombs V, Kai W, Dugal J, Kandath D, Kostedt G, Kaplan K, Cook S, Kapoor A, Ruggiero M, Karunaratne H, Behm K, Kastelic R, Davis C, Keller R, Keller J, Kerkering M, Bartholomaus D, Kersh R, Buhler A, Kesselbrenner M, DiCorcia L, Khan B, Binns M, Khan M, Khan G, Kindman L, Averett P, Korpas D, Godfrey C, Kotha P, Sanchez E, Kozlowski J, Watts S, Krichmar P, Marquez D, Laliotis A, Jauregui V, Lambert C, Coyle GS, Landau C, Ferguson D, Lang J, Simmons T, Langevin E, Faucett S, Ledbetter L, Royse H, Lentz M, Smith D, Lesser M, Hartley L, Lewis D, Bonds C, Lillestol M, Miller D, Ling L, Murphy R, Littlefield R, Wofford E, Lomnitz D, Lone B, Davids M, Looby R, Ault S, Lui H, Wright H, Lurie M, Edelstein J, Macomber J, Bush D, Magee A, Doctor A, Mainigi S, Lisiecki B, Makam S, Casas R, Mandviwala M, Marar I, Rabadi Marar D, Marenberg M, Bedenko E, Massin E, Hicks T, McCartney M, Stubbs L, McGarvey J, Schwarz L, McGuire K, McKenzie M, Rodkey K, McKnight T, Paul J, McLaurin B, Lack A, Mega J, Marti J, Meholick A, Skinner J, Mehrle A, Wall J, Mendelson R, Cervellione K, Mercado A, Cajulis C, Michlin B, Romero Colon J, Milas J, Sanders D, Miller R, Sanchez S, Miller S, Gryczan J, Mody F, Strugatsky S, Moran J, Garner S, Morledge J, Bowman B, Mouhaffel A, Parrott N, Mounsey P, Schuler C, Mowdy M, Todd S, Mullen P, Raziano S, Murphy A, Oehmann V, Nadar V, Parker A, Naidu J, West M, Nallasivan M, Goza J, Nguyen T, Nomanee S, Nielsen R, Wilmot M, Oberoi M, Thakkar N, Oppenheimer K, McCormick J, Orchard R, Garcia L, Osborne J, Gonzalez M, Oza S, Joseph L, Patnam S, Dennison K, Pavon H, Gorry N, Pearlstein R, Montayne S, Pentz W, Duncan D, Peters P, Chacon L, Petruzziello F, Morlando F, Pettis K, Brown F, Pezzella S, Kirk D, Poulathas A, Cush S, Pratt R, Neeper L, Pribble A, Lowe K, Pudi K, Sham L, Pugeda J, Ebert J, Quadrel M, Rafla E, Quinlan E, Reed C, Quinn J, Hemmen C, Rama P, Domingo D, Redondo V, Wroblewski J, Renzi M, Stanley E, Richwine R, Pazier P, Riofrio K, Braun D, Robinson J, Cherrico M, Roehll W, Hollihan P, Rosado, Barnhorst M, Rosado J, Bamhorst M, Rosen R, Martin C, Ross S, Freeman R, Ruoff G, Nelson T, Sacco J, Ball E, Samal A, Schomburg J, Sandberg J, Lafave J, Savin V, Clifton R, Schaefer S, Fekete A, Schneider R, Schneider W, Schulman D, Mercer S, Seals A, Ullig T, Holt A, Seide H, Mather N, Shah G, Witt P, Shalaby A, Seese M, Shanes J, Fleets J, Shaoulian E, Hren A, Sheikh K, Hengerer T, Shih H, Browning J, Shoukfeh M, Stephenson L, Siler T, Champagne M, Simpson P, Meyer R, Singh N, Turner K, Singh V, Nelson M, Skierka R, Hughes B, Keene R, Smith R, Hodnett P, Spangenthal S, Thomason L, Sperling M, Vasquez E, Spivack E, McCartney P, Staniloae C, Liu M, Steljes A, Cox C, Struble R, Vittitow T, Suresh D, Frost J, Swerchowsky V, Freemyer D, Szulawski I, Herwehe S, Tahirkheli N, Springer K, Takata T, Bruton T, Talano J, Leo L, Tami L, Corchado D, Tatarko M, Swauger M, Tawney K, Dastoli K, Teague S, Young K, Tee H, Mitchell T, Teixeira J, Southam D, Torres M, Tucker P, Salas L, Updegrove J, Hanna K, Val Mejias J, Harrelson KG, Vemireddy D, Cardoza T, Verma S, Parsons T, Vicari R, Warren K, Vijay N, Washam M, Vossler M, Kilcup S, Walsh R, Renaud K, Ward S, Locklear T, Waxman F, Sanchez G, Weiss R, St Laurent B, Westcott J, Williams D, Gibson C, Williams R, Dowling C, Willis J, VonGerichten S, Wood K, Capasso Gulve E, Worley S, Pointer S, Yarows S, Sheehan T, Yasin M, Yi J, Dongas B, Yousuf K, Zakhary B, Curtis S, Zeig S, Mason T, Zellner C, Harden M, Roper E, Waseem M, Grammer M., PERRONE FILARDI, PASQUALE, Cardiovascular Division (SZG), Brigham and Women's Hospital [Boston], Mount Sinai Medical Center, Icahn School of Medicine at Mount Sinai [New York] (MSSM), University Hospitals Case Medical Center (CLEVELAND - UHCMC), University Hospitals Case Medical Center, Jefferson Medical College (JMC), Thomas Jefferson University Hospitals, Thrombosis and Atherosclerosis Research Institute (TARI), McMaster University [Hamilton, Ontario], University Hospital Brno, Institute of Cardiology (WARSAW - Cardiology), Institute of Cardiology, Cardiology Research Center (MOSCOU - CRC), Cardiology Research Center, National Hopital Organization (OSAKA - NHO), Osaka National Hospital, Université de Brest (UBO), Centre d'Investigation Clinique (CIC - Brest), Université de Brest (UBO)-Institut National de la Santé et de la Recherche Médicale (INSERM), Graduate School, Endocrinology, ACS - Amsterdam Cardiovascular Sciences, Cardiology, Nursing, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, General Internal Medicine, Giugliano, Rp, Ruff, Ct, Braunwald, E, Murphy, Sa, Wiviott, Sd, Halperin, Jl, Waldo, Al, Ezekowitz, Md, Weitz, Ji, Špinar, J, Ruzyllo, W, Ruda, M, Koretsune, Y, Betcher, J, Shi, M, Grip, Lt, Patel, Sp, Patel, I, Hanyok, Jj, Mercuri, M, Antman, Em, Comi, Giancarlo, ENGAGE AF TIMI 48, Investigators, Robert P., Giugliano, Christian T., Ruff, Eugene, Braunwald, Sabina A., Murphy, Stephen D., Wiviott, Jonathan L., Halperin, Albert L., Waldo, Michael D., Ezekowitz, Jeffrey I., Weitz, Jind?ich, ?pinar, Witold, Ruzyllo, Mikhail, Ruda, Yukihiro, Koretsune, Joshua, Betcher, Minggao, Shi, Laura T., Grip, Shirali P., Patel, Indravadan, Patel, James J., Hanyok, Michele, Mercuri, Elliott M., Antman, Morin, Se, Hoffman, Eb, Deenadayalu, N, Grip, L, Lanz, H, Curt, V, Duggal, A, Hanyok, J, Davé, J, Morgan, D, Choi, Y, Jin, J, Xie, J, Crerand, W, Kappelhof, J, Maxwell, W, Skinner, M, Patel, S, Selicato, G, Otto C., Jr, Reissner, C, Smith, K, Ostroske, J, Ron, A, Giugliano, R, Connolly, S, Camm, J, Ezekowitz, M, Halperin, J, Waldo, A, Paolasso, E, Aylward, P, Heidbuchel, H, Nicolau, Jc, Goudev, A, Roy, D, Weitz, J, Corbalán, R, Yang, Y, Botero, R, Bergovec, M, Ŝpinar, J, Grande, P, Hassager, C, Voitk, J, Huikuri, H, Nieminen, M, Blanc, Jj, Leheuzey, Jy, Mitrovic, V, Alexopoulos, D, Sotomora, G, Kiss, R, Somaraju, B, Lewis, B, Merlini, P, Metra, M, Yamashita, T, García Castillo, A, Ophuis, T, White, H, Atar, D, Horna, M, Babilonia, N, Morais, J, Dorobantu, M, Ostojic, M, Duris, T, Dalby, A, Chung, N, Zamorano, Jl, Juul Möller, S, Moccetti, T, Chen, Sa, Sritara, P, Oto, A, Parkhomenko, A, Senior, R, Verheugt, F, Skene, A, Anderson, J, Bauer, K, Easton, Jd, Goto, S, Wiviott, S, Lowe, C, Awtry, E, Berger, Cj, Croce, K, Desai, A, Gelfand, E, Goessling, W, Greenberger, Nj, Ho, C, Leeman, De, Link, M, Norden, Ad, Pande, A, Rost, N, Ruberg, F, Silverman, S, Singhal, A, Vita, Ja, Vogelmann, O, Gonzalez, C, Ahuad Guerrero, R, Rodriguez, M, Albisu, J, Rosales, E, Allall, O, Reguero, M, Alvarez, C, Garcia, M, Ameriso, S, Ameriso, P, Amuchastegui, M, Caceres, M, Beloscar, J, Petrucci, J, Berli, M, Budassi, N, Valle, M, Bustamante Labarta, G, Saravia, M, Caccavo, A, Fracaro, V, Cartasegna, L, Novas, V, Caruso, O, Zarandon, R, Colombo, H, Morandini, M, Cuello, J, Rosell, M, Cuneo, C, Bocanera, M, D'Amico, A, Cendali, G, Dran, R, Moreno, V, Estol, C, Davolos, M, Facello, A, Facello, M, Falu, E, Iriarte, M, Femenia, F, Arrieta, M, Fuselli, J, Zanotti, A, Gant Lopez, J, Meiller, F, Garcia Duran, R, Perlo, D, Garrido, M, Ceirano, C, Giacomi, G, Eden, M, Giannaula, R, Huerta, M, Goicoechea, R, von Wulffen, M, Hominal, M, Bianchini, M, Jure, H, Jure, D, Kevorkian, R, Monaco, F, Lanternier, G, Belcuore, M, Liniado, G, Iglesias, M, Litvak, B, Nigro, A, Llanos, J, Vignau, S, Lorente, C, Shatsky, K, Lotti, J, Raimondi, G, Mackinnon, I, Carne, M, Manuale, O, Calderon, M, Marino, J, Funes, I, Muntaner, J, Gandur, H, Nul, D, Verdini, E, Piskorz, D, Tommasi, A, Povedano, G, Casares, E, Pozzer, D, Fernandez, E, Prado, A, Venturini, C, Ramos, H, Navarrete, S, Alvarez, M, Sanchez, A, Bowen, L, Sanjurjo, M, Codutti, O, Saravia Toledo, S, Formoso, I, Schmidberg, J, Goloboulicz, A, Schygiel, P, Buzzetti, C, Severino, P, Morara, P, Sosa Liprandi, M, Teves, M, Vico, M, Morell, Y, Anderson, C, Paraskevaidis, T, Arstall, M, Hoffmann, B, Colquhoun, D, Price Smith, S, Crimmins, D, Slattery, A, Dart, A, Kay, S, Davis, S, Silver, G, Flecknoe Brown, S, Roberts, J, Gates, P, Jones, S, Lehman, R, Morrison, H, Mckeirnan, M, Li, J, Paul, V, Batta, C, Purnell, P, Perrett, L, Szto, G, O'Shea, V, Capiau, L, Banaeian, F, De Bleecker, J, de Koning, K, De Tollenaere, M, De Bruyne, L, Desfontaines, P, Tincani, G, Meeusen, K, Herzet, J, Malmendier, D, Mairesse, G, Raepers, M, Parqué, J, Clinckemaille, N, Scavée, C, Huyberechts, D, Stockman, D, Jacobs, C, Vandekerckhove, Y, Derycker, K, Vanwelden, J, van Welden, J, Vervoort, G, Mestdagh, I, Vrolix, M, Beerts, C, Wollaert, B, Denie, D, Amato Vincenzo de Paola, A, Coutinho, E, Andrade Lotufo, P, de Melo, Rf, Atie, J, Motta, C, Augusto Alves da Costa, F, Ferraz, Rf, Bertolim Precoma, D, Sehnem, E, Botelho, R, Cunha, S, Brondani, R, Fleck, N, Chaves Junior, H, Silva, J, Costantini, C, Barroso, D, De Patta, M, Pereira, V, Duda, N, Laimer, R, Dutra, O, Morgado, S, Faustino Saporito, W, Seroqui, M, Ferreira, L, Araújo, E, Finimundi, H, Daitz, C, Gagliardi, R, Pereira, G, Gomes, M, Gomes, A, Guimarães, A, Ninho, L, Jaeger, C, Pereira, L, Jorge, J, Cury, C, Kaiser, S, Almeida, A, Kalil, C, Radaelli, G, Kunz Sebba Barroso de Souza, W, Morales, K, Leaes, P, Luiz, Ro, Pimenta Almeida, J, Gozalo, A, Reis, G, Avellar, K, Reis Katz Weiand, L, Leipelt, J, Rocha, J, Barros, R, Rodrigues, L, Rocha, Mr, Rodrigues, A, Rodrigues, D, Rossi dos Santos, F, Pagnan, Lg, Sampaio, R, do Val, R, Saraiva, J, Vicente, C, Simoes, M, Carraro, A, Sobral Filho, D, Lustosa, E, Villas Boas, F, Almeida, M, Zimmermann, S, Zimmermann, Eb, Chompalova, B, Parishev, G, Denchev, S, Milcheva, N, Donova, T, Gergova, V, Georgiev, B, Kostova, E, Kinova, E, Hergeldjieva, V, Kamenova, P, Manolova, A, Vasilev, I, Mihov, A, Miteva, B, Mincheva, V, Stoyanovski, V, Nikolov, F, Vasilev, D, Pencheva, G, Kostov, K, Petranov, S, Milusheva, T, Popov, A, Staneva, A, Momchilova Lozeva, D, Todorov, G, Nyagina, M, Tumbev, H, Tumbeva, D, Tzekova, M, Kitova, M, Manoylov, E, Archibald, J, Antle, S, Bhargava, R, Stafford, C, Bose, S, Hundseth, M, Cha, J, Otis, J, Chehayeb, R, Lepage, C, Chilvers, M, Vansickle, L, Cleveland, D, Valley, S, Constance, C, Gauthier, M, Costi, P, Masson, C, Coutu, B, Denis, I, du Preez, M, Kubanska, A, Dufresne, M, Krider, J, Eikelboom, J, Zondag, M, Fortin, C, Viau, C, Green, M, Houbraken, D, Hatheway, R, Mabee, J, Heath, J, Scott, L, Ho, K, Ho, V, Hoag, G, Standring, R, Huynh, T, Perkins, L, Kouz, S, Roy, M, Labonte, R, Dewar, C, Lainesse, A, St Germain, L, Lam, S, Lam, H, Lichtenstein, T, Roberts, P, Luton, R, Douglas, S, Ma, P, Seib, M, Maccallum, C, Matthews, J, Malette, P, Vaillancourt, T, Maranda, C, Studenikow, E, Mawji, A, Morely, A, Morrison, D, Roth, M, Mucha, M, Najarali, A, Lamoureux, U, Nicholson, R, O'Hara, G, Banville, P, O'Mahony, W, Bolton, R, Parkash, R, Carroll, L, Pesant, Y, Sardin, V, Polasek, P, Turri, L, Qureshi, A, Nethercott, C, Ricci, J, Bozek, B, Rupka, D, Marchand, C, Shu, D, Silverio, G, St Hilaire, R, Morissette, A, Sussman, J, Kailey, P, Syan, G, Bobbie, C, Talajic, M, David, D, Talbot, P, Tremblay, M, Teitelbaum, I, Teitelbaum, J, Velthuysen, G, Giesbrecht, L, Wahby, R, Morley, A, Wharton, S, Caterini, T, Woodford, T, Balboa, W, Matus, Lr, Bugueño, C, Mondaca, Pm, Cobos, J, Obreque, C, Corbalan, R, Parada, A, Florenzano, F, Diaz, Pa, Lopetegui, M, Rebolledo, C, Manriquez, L, Silva, Lm, Martinez, D, Llamas, Rr, Opazo, M, Pérez, Mc, Pincetti, C, Carrasco, Gt, Potthoff, S, Staub, Jz, Campisto, Y, Stockins, B, Lara, Cl, Yovaniniz, P, Azua, Mg, Bai, F, Xu, Gl, Chen, Jz, Xie, Xd, Chen, Xp, Zhang, X, Dong, Yg, Feng, C, Fu, G, Zhang, P, Hong, K, You, Zg, Hong, L, Qiu, Y, Jiang, Xj, Qu, Z, Li, L, Liu, H, Li, Tf, Kong, Yq, Li, Wm, Liu, B, Li, Zq, Liu, Y, Liao, Dn, Gu, Xj, Liu, L, Lu, Zh, Ma, Sm, Yang, Zy, Wang, Dm, Qi, Sy, Wang, Gp, Shi, Xj, Wei, M, Huang, D, Wu, Sl, Li, Ye, Xu, Jh, Gu, Jy, Xu, Ym, Liang, Yz, Yang, K, Li, Ay, Yang, Yj, Zheng, X, Zheng, Y, Gao, M, Yin, Yh, Xu, Yp, Yu, B, Li, Ll, Yuan, Zy, Qiang, H, Zhang, Hq, Lin, Yn, Zhang, Z, Kang, H, Zhao, Rp, Han, Rj, Zhao, Xl, Wang, Jq, Zheng, Zq, Li, Bg, Zhou, Sx, Zhang, Yl, Accini, J, Accini, M, Cano, N, Pineda, Ll, Delgado Restrepo, J, Arroyave, C, Fernández Ruiz, R, Diaz, Ia, Hernandez, H, Delgado, P, Jaramillo Muñoz, C, Builes, A, Manzur, F, Rodriguez, Er, Moncada Corredor, M, Giraldo, Dl, Orozco Linares, L, Fonseca, J, Quintero, A, Gonzales, C, Sanchez Vallejo, G, Mejia, Ip, Bagatin, J, Carevic, V, Car, S, Jeric, M, Ciglenecki, N, Tusek, S, Ferri Certic, J, Romic, I, Francetic, I, Ausperger, Km, Jelic, V, Jurinjak, Sj, Knezevic, A, Buksa, B, Samardzic, P, Lukenda, Kc, Steiner, R, Kirner, D, Sutalo, K, Bakliza, Z, Vrazic, H, Lucijanic, T, Bar, M, Brodova, P, Berka, L, Kunkelova, V, Brtko, M, Burianova, H, Cermak, O, Elbl, L, Ferkl, R, Florian, J, Francek, L, Golan, L, Gregor, P, Honkova, M, Hubac, J, Jandik, J, Jarkovsky, P, Jelinek, Z, Jerabek, O, Jirmar, R, Kobza, R, Kochrt, M, Kostkova, G, Kosek, Z, Kovar, P, Kuchar, R, Kvasnicka, J, Ludka, O, Machova, V, Krocova, E, Melichar, M, Nechanicky, R, Olsr, J, Peterka, K, Petrova, I, Havlova, I, Pisova, J, Podrazil, P, Jirsova, E, Reichert, P, Slaby, J, Spacek, R, Spinar, J, Labrova, R, Vodnansky, P, Samkova, D, Zidkova, E, Dodt, K, Christensen, H, Christensen, L, Loof, A, Ibsen, H, Madsen, H, Iversen, H, Veng Olsen, T, Nielsen, H, Olsen, R, Overgaard, K, Petrovic, V, Raymond, I, Raae, D, Sand, N, Svenningsen, A, Torp Pedersen, C, Jakobsen, U, Wiggers, H, Serup Hansen, K, Kaik, J, Stern, A, Kolk, R, Laane, E, Rivis, L, Paumets, M, Laheäär, M, Rosenthal, A, Rajasalu, R, Vahula, V, Ratnik, E, Kaarleenkaski, S, Hussi, E, Valpas, S, Jäkälä, P, Lappalainen, T, Mäenpää, A, Viitaniemi, J, Nyman, K, Sankari, T, Rasi, H, Salminen, O, Virtanen, V, Nappila, H, Le Heuzey, J, Agraou, B, El Jarroudi, F, Amarenco, P, Boursin, P, Babuty, D, Boyer, M, Belhassane, A, Berbari, H, Blanc, J, Dias, P, Coisne, D, Berger, N, Decoulx, E, El Jarroudi, M, Dinanian, S, Arfaoui, M, Hermida, J, Deruche, E, Kacet, S, Corbut, S, Poulard, J, Leparree, S, Roudaut, R, Duprat, C, Al Zoebi, A, Wurow, A, Bernhardt, P, Dichristin, U, Berrouschot, J, Vierbeck, S, Beyer Westendorf, J, Sehr, B, Bouzo, M, Schnelzer, P, Braun, R, Ladenburger, K, Buhr, M, Weihrauch, D, Contzen, C, Kara, M, Daut, W, Ayasse, D, Degtyareva, E, Kranz, P, Drescher, T, Herfurth, B, Faghih, M, Forck Boedeker, K, Schneider, K, Fuchs, R, Manuela, W, Grigat, C, Otto, A, Hartmann, A, Peitz, M, Heuer, H, Dieckheuer, U, Hoffmann, U, Dorn, S, Hoffmann, S, Schuppe, M, Horacek, T, Fink, P, Junggeburth, J, Schmid, S, Jungmair, W, Schoen, B, Kleinecke Pohl, U, Meusel, P, Koenig, H, Bauch, F, Lohrbaecher Kozak, I, Grosse, B, Lueders, S, Venneklaas, U, Luttermann, M, Wulf, M, Maus, O, Hoefer, K, Meissner, G, Braemer, U, Meyer Pannwitt, U, Frahm, E, Vogt, S, Muegge, A, Barbera, S, Mueller Glamann, M, Raddatz, K, Piechatzek, R, Lewinsky, D, Pohl, W, Proskynitopoulos, N, Kuhlmann, M, Rack, K, Pilipenko, H, Rinke, A, Kühlenborg, A, Schaefer, A, Szymanowski, N, Schellong, S, Frommhold, R, Schenkenberger, I, Finsterbusch, T, Dreykluft, K, Schiewe, C, Schmidt, A, Schmidt, M, Schreckenberg, A, Hellmers, J, Seibert, H, Gold, G, Sohn, H, Baylacher, M, Spitzer, S, Bonin, K, Stoehring, R, Taggeselle, J, Zarpentin, C, Veltkamp, R, Ludwig, I, Voehringer, Buchholz, M, Weyland, K, Winkelmann, B, Buelow Johansen, B, Wolde, C, Winter, K, Mavronasiou, E, Bourlios, P, Tziortziotis, A, Karamitsos, C, Exarchou, E, Kifnidis, K, Daskalaki, A, Moschos, N, Dimitra, K, Olympios, C, Kartsagkoulis, E, Pyrgakis, V, Korantanis, K, Ayau Milla, O, Ramirez Vde, L, Guzman Melgar, I, Jimenez, T, Ovando Lavagnino, A, Guevara, S, Rodas Estrada, M, Sanchez, M, Pozuelos, Jm, Sanchez Samayoa, C, Guerra, L, Velasquez Camas, L, Almaraz, Sp, Dioszeghy, P, Muskoczki, E, Edes, I, Szatmari, J, Fiok, J, Varga, A, Kanakaridisz, N, Kosztyu, M, Kis, E, Feil, Jf, Jakal, A, Koczka, M, Kovacs, I, Baranyai, M, Kovacs, Z, Lupkovics, G, Karakai, Hh, Matoltsy, A, Kiss, T, Medvegy, M, Kiss, K, Merkely, B, Kolumban, E, Nagy, A, Palinkas, A, Toth, Sr, Sayour, A, Bognar, A, Simor, T, Ruzsa, D, Sipos, T, Szakal, I, Tomcsanyi, J, Marosi, A, Vertes, A, Kincses, M, Malhan, S, Abdullakutty, J, Agarwal, D, Ranka, R, Arneja, J, Memon, A, Arora, V, Shree, R, Avvaru, G, Shaikh, A, Babu, P, Rao, B, Babu, R, Reddy, J, Banker, D, Sheth, T, Benjarge, P, Surushe, S, Bharani, A, Solanki, R, Bhargava, V, Rathi, A, Biniwale, A, Bhuti, M, Calambur, N, Karnwal, N, Chopda, M, Mali, N, Goyal, N, Saini, A, Gupta, J, Singh, P, Hadan, S, Savanth, P, Hardas, S, Thakor, G, Hiremath, J, Ghume, A, Jain, R, Pahuja, M, Joseph, S, Oommen, D, Joseph, J, Thomas, R, Joshi, H, Iby, Kale, V, Raut, N, Kandekar, B, Kandekar, S, Kishore, R, Krishnan, H, Kotiwale, V, Kulkarni, R, Deokar, M, Kulkarni, G, Lawande, A, Kumar, P, Karpuram, M, Kumar, A, Francis, J, Kumbla, M, Anthony, A, Lavhe, P, Kale, M, Mardikar, H, Bhaskarwar, P, Mathur, A, Sharma, P, Menon, J, Francis, V, Namjoshi, D, Shelke, S, Narendra, J, Natarajan, S, Oomaan, A, Gurusamy, P, Angel, J, Purayil, Mp, Shams, S, Pandurangi, U, Sababathi, R, Parekh, P, Jasani, B, Patki, N, Babbar, A, Pinto, B, Kharalkar, H, Premchand, R, Jambula, H, Rao, M, Vuriya, A, Ravi Shankar, A, Reddy, R, Bekal, S, Barai, A, Saha, D, Gadepalli, R, Sant, H, Jadhav, D, Sarna, M, Arora, T, Sawhney, J, Singh, R, Sethi, K, Bansal, N, Sethia, A, Sethia, S, Shetty, G, Sudheer, R, Singh, G, Gupta, R, Srinivas, A, Thankaraj, L, Varma, S, Kaur, A, Vinod, Mv, Thakur, B, Zanwar, I, Dharmarao, A, Atar, S, Lasri, E, Dicker, D, Marcoviciu, D, Elias, M, Ron, Ga, Francis, A, Ghantous, R, Goldhaber, A, Goldhaber, M, Gottlieb, S, Rouwaida, S, Grossman, E, Dagan, T, Hasin, Y, Roshrosh, M, Hayek, T, Majdoub, A, Klainman, E, Genin, I, Lahav, M, Gilat, T, Ben Ari, M, Lishner, M, Karny, M, Ouzan, E, Givoni, H, Rozenman, Y, Logvinenko, S, Schiff, E, Sterlin, J, Shochat, M, Aloni, I, Swissa, M, Belatsky, V, Tsalihin, D, Kisos, D, Zeltser, D, Platner, N, Berni, A, Giovannelli, F, Boriani, G, Cervi, E, Comi, G, Peruzzotti, L, Cuccia, C, Forgione, C, De Caterina, R, De Pace, D, De Servi, S, Mariani, M, Di Lenarda, A, Mazzone, C, Di Pasquale, G, Di Niro, M, Fattore, L, Bosco, B, Grassia, V, Murena, E, Laffi, Gaggioli, G, Lo Pinto, G, Raggi, F, Marino, P, Francalacci, G, Babbolin, M, Bulgari, M, Penco, M, Lioy, E, PERRONE FILARDI, Pasquale, Marciano, C, Pirelli, S, Paradiso, G, Piseddu, G, Fenu, L, Raisaro, A, Granzow, K, Rasura, M, Cannoni, S, Severi, S, Breschi, M, Toschi, V, Gagliano, M, Zacà, V, Furiozzi, F, Hirahara, T, Akihisa, U, Masaki, W, Ajioka, M, Matsushita, C, Anzai, T, Mino, K, Arakawa, S, Tsukimine, A, Endo, H, Fujiwara, M, Fujii, K, Kozeni, S, Fujii, E, Kotera, M, Fujimoto, S, Omae, K, Fujimoto, K, Ichishita, Y, Fujita, T, Ito, Y, Fukamizu, S, Harada, J, Fukuda, N, Fujimoto, C, Funazaki, T, Yamaguchi, A, Furukawa, Y, Kamitake, C, Hagiwara, N, Naganuma, M, Hara, S, Kumagai, S, Harada, K, Fuki, Y, Haruna, T, Nakahara, Y, Hashimoto, Y, Shimazu, Y, Hiasa, Y, Oga, Y, Higashikata, T, Nakagawa, Y, Hirayama, A, Kawaguchi, A, Iesaka, Y, Miyamoto, C, Iijima, T, Higuchi, K, Ino, H, Noguchi, H, Inomata, T, Nakamura, K, Ishibashi, Y, Nozaki, T, Ishii, Y, Tomita, H, Ishimaru, S, Ise, M, Itamoto, K, Ito, T, Onishi, M, Iwade, K, Sakuma, Y, Iwasaki, T, Nagatome, H, Kakinoki, S, Adachi, C, Kamakura, S, Nakahara, F, Kamijo, M, Iida, S, Kamiyama, K, Fujii, R, Kato, K, Ishida, A, Kazatani, Y, Ichikawa, Y, Kitazawa, H, Igarashi, C, Kobayashi, Y, Kikuchi, R, Kohno, M, Tamura, S, Yumoto, I, Kurabayashi, M, Koya, E, Masuyama, T, Kaneno, Y, Matsuda, K, Ebina, E, Meno, H, Satake, M, Mita, T, Takeda, M, Miyamoto, N, Kimizu, T, Miyauchi, Y, Sakamoto, S, Munemasa, M, Murata, J, Nagai, Y, Sakata, Y, Naito, S, Oyama, H, Nishi, Y, Nagase, T, Ochiai, J, Junko, H, Ogawa, T, Sugeno, M, Oguro, H, Tanabe, M, Okada, K, Moriyama, Y, Okajima, K, Nakashima, M, Okazaki, O, Wada, H, Okishige, K, Kitani, S, Okumura, K, Narita, Y, Onaka, H, Moriyama, H, Ozaki, Y, Tanikawa, I, Sakagami, S, Nakano, A, Sakuragi, S, Hayashi, N, Sakurai, S, Ooki, H, Sasaki, T, Oosawa, N, Satoh, A, Fujimoto, E, Seino, Y, Narumi, M, Shirai, T, Shigenari, M, Shoji, Y, Ueda, J, Sugi, K, Miyazaki, E, Sumii, K, Asakura, H, Takagi, M, Mohri, S, Takahashi, W, Yoshida, K, Takahashi, A, Kishi, N, Takahashi, T, Sakurai, Y, Takeda, K, Yahata, A, Takenaka, T, Yamagishi, K, Takeuchi, S, Watanabe, E, Tanaka, K, Uchida, M, Tanouchi, J, Nishiya, Y, Tsuboi, H, Tsuboi, N, Terakura, K, Uematsu, M, Yasumoto, S, Ueyama, Y, Usuda, K, Sakai, Y, Yagi, M, Sato, A, Yagi, H, Kuroda, T, Yamabe, H, Sakamoto, Y, Yamada, T, Yamano, R, Yamagishi, T, Sasaki, S, Yamamoto, Y, Yamashina, A, Takiguchi, M, Yonehara, T, Yoshino, H, Nomura, H, Yoshioka, K, Fujiwara, Y, Bayram Llamas, E, Hurtado, A, Calvo Vargas, C, Limon, Mc, Cardona Muñoz, E, Hernandez, S, Carrillo, J, Delgadillo, T, Cásares Ramirez, M, Valles, Jf, Garcia, N, Colin, Ma, Garcia Castillo, A, Jaramillo, A, Leiva Pons, J, de la Mora, S, Llamas Esperón, G, Grajales, A, Mendez Machado, G, Avila, H, Ruiz, Ln, Magallanes, G, Sánchez Díaz, C, Ortiz, A, Sánchez, Rv, Velazquez, Em, Alhakim, M, van Welsen, I, Bruning, T, Jones, A, Buiks, C, de Groot, J, Radder, I, de Vos, R, Hazeleger, R, Daniels, R, Kietselaer, B, Muijs, L, Mannaerts, H, Kooiman, E, Mevissen, H, van der Heijden, D, Hofmeyer, H, Anscombe, R, O'Meeghan, T, Kjentjes, M, Benatar, J, Borthwick, L, Doughty, R, Copley, M, Fisher, R, Monkley, R, Green, B, Scott, D, Hamer, A, Tomlinson, J, Hart, H, Turner, A, Cammell, R, Troughton, R, Skelton, L, Young, C, Kennett, K, Claussen, H, Hofsøy, K, Melbue, R, Sandvik, J, Thunhaug, H, Tveit, A, Enger, S, Bustamante, G, Guillen, Mt, Cabrera, J, Mendoza, Re, Chavez, C, Luna, C, Lema, J, Carrion, A, Llerena, N, Bedregal, Sa, Medina Palomino, F, Rodriguez, J, Minchola, J, Bautista, C, Negron Miguel, S, Armas, Bh, Rodriguez, A, Romero, N, Torres, P, Rodriguez, Kf, Yanac Chavez, P, Delgado, S, Sambaz, Cm, Barcinas, R, Zapanta, M, Coching, R, Vallenas, M, Matiga, G, Enad, C, Rogelio, G, Joaquin, F, Roxas A., Jr, Gilo, L, To, R, Aquino, M, Villamor, L, Nario, K, Adamus, J, Korzeniowska Adamus, J, Baszak, J, Bronisz, M, Cieslak, B, Busz Papiez, B, Krzystolik, A, Cymerman, K, Dabrowska, M, Ptak, A, Derlaga, B, Laskowska Derlaga, E, Domanska, E, Guziewicz, M, Gieroba, A, Zajac, E, Gniot, J, Mroczkowski, P, Januszewicz, A, Makowiecka Ciesla, M, Jazwinska Tarnawska, E, Ciezak, P, Jurowiecki, J, Kaczmarek, B, Pacholska, A, Kaminski, L, Kania, G, Tymendorf, K, Karczmarczyk, A, Kaliszczak, R, Konieczny, M, Benicka, E, Korzeniak, R, Borowski, W, Krzyzanowski, W, Muzyk Osikowicz, M, Kus, W, Lesnik, J, Wierzykowski, T, Lewczuk, J, Stopyra Poczatek, M, Lubinski, A, Szymanska, K, Lysek, R, Jaguszewska, G, Matyszczak Toniak, L, Sznajder, R, Wnetrzak Michalska, R, Kosmaczewska, A, Mazur, S, Chmielowski, A, Miekus, P, Kosmalska, K, Mosiewicz, J, Myslinski, W, Napora, P, Biniek, D, Nessler, J, Nessler, B, Niezgoda, K, Nej, A, Nowak, J, Olszewski, M, Podjacka, D, Janczewska, D, Pogorzelska, H, Polaszewska Pulkownik, V, Bojanowska, E, Raczak, G, Zienciuk Krajka, A, Rewinska, H, Rozmyslowicz Szerminska, W, Ronkowski, R, Norwa Otto, B, Sendrowski, D, Spyra, J, Szolkiewicz, M, Malanska, A, Turbak, R, Wrobel, W, Muzalewski, P, Wysokinski, A, Kudlicki, J, Zarebinski, M, Krauze, R, Zielinski, M, Nawrot, M, Matias, F, Correia, J, Gil, V, Lopes, S, Madeira, J, Maymone, D, Martins, D, Neves, E, Monteiro, P, Oliveira, D, Marques, Al, Castro, C, Salgado, A, Gonçalves, A, Sao Marcos, H, Santos, O, Nunes, Lv, Sao Teotonio, H, Santos, J, Soares, D, Albulescu, P, Ciortea, M, Apetrei, E, Matei, C, Bartos, D, Badila, E, Bengus, C, Ochean, V, Bobescu, E, Doka, B, Bolohan, F, Ciobotaru, G, Andor, M, Coman, I, Ghionea, M, Constantinescu, M, Creteanu, M, Parasteac, M, Cristea, M, Anciu, M, Crisu, D, Jemna, D, Dobre, I, Voicu, O, Dobreanu, D, Sirbu, I, Dragomir, D, Jurca, S, Iosipescu, L, Costache, L, Minescu, B, Serban, D, Pop, C, Cozma, M, Popescu, M, Ardelean, A, Sipciu, D, Plosca, P, Stamate, S, Spinu, C, Topolnitchi, L, Topolnitchi, O, Tudoran, M, Tudoran, C, Zhukova, N, Arutyunov, G, Chernyavskaya, T, Ballyuzek, M, Alexandrova, L, Barbarash, O, Bashkireva, A, Bart, B, Larina, V, Belenky, D, Kosolapov, Y, Berns, S, Yukhno, E, Bokarev, I, Khlevchuk, T, Chumakova, G, Pokutneva, O, Demko, A, Masin, A, Dovgalevsky, P, Puchinyan, N, Drapkina, O, Zyatenkova, E, Egorova, L, Esip, V, Kirichek, N, Filatov, A, Soin, I, Gilinskaya, O, Valuyshkih, E, Glezer, M, Valovyeva, S, Golitsyn, S, Kratskina, T, Goloshchekin, B, Laptev, I, Gratsiansky, N, Mazovets, O, Karpov, Y, Buza, V, Kosenko, B, Khirmanov, V, Kireenkov, I, Khokhlov, A, Sinitsina, O, Khokhlov, R, Tsareva, E, Khrustalev, O, Khrustalev, A, Kostenko, V, Karabalieva, S, Koziolova, N, Polyanskaya, E, Kozyrev, O, Kostenko, O, Kuznetsov, V, Rychkov, A, Lavrova, O, Tereschenko, L, Levashov, S, Volkova, E, Libis, R, Maslova, A, Libov, I, Moiseeva, Y, Lila, A, Belousova, L, Lukyanov, Y, Lamden, D, Nikolaev, K, Nikolaev, A, Nikolskaya, I, Khromova, O, Novikova, N, Patrusheva, S, Panchenko, E, Laguta, P, Panov, A, Nilk, R, Polkanova, E, Matveeva, I, Poluyanova, N, Pikalova, N, Raskina, T, Letaeva, M, Rebrov, A, Karoli, N, Repin, M, Rodina, N, Shaposhnik, I, Lebedev, E, Shogenov, Z, Agirov, M, Sidorenko, B, Vorontsova, S, Sinitsina, I, Orlov, V, Golshmid, M, Sizova, Z, Lapidus, N, Sobolev, K, Erofeeva, S, Suprun, E, Dronov, D, Tarasov, N, Isakov, L, Tereshenko, S, Kositsyna, I, Tikhonova, E, Solovyev, A, Timofeev, A, Bulygin, S, Ustyugov, S, Rossovskaya, M, Vishnevsky, A, Kirgizova, A, Volkov, D, Yakusevich, V, Petrochenko, A, Yakushin, S, Nikulina, N, Zateyshchikov, D, Zotova, I, Zateyshchikova, A, Mankhaeva, B, Zenin, S, Kononenko, O, Zubeeva, G, Motylev, I, Apostolovic, S, Djordjevic Radojkovic, D, Celic, V, Majstorovic, A, Cemerlic Adjic, N, Bjelobrk, M, Despotovic, N, Erceg, P, Ilic, S, Ilic, B, Krotin, M, Djokovic, A, Miloradovic, V, Djokic, I, Otasevic, P, Tasic, N, Potpara, T, Polovina, M, Putnikovic, B, Kalezic, T, Seferovic, P, Milinkovic, I, Tavciovski, D, Davicevic, Z, Vasiljevic Pokrajcic, Z, Mitrovic, P, Vujisic Tesic, B, Tesic, M, Ambrovicova, V, Ambrovic, I, Banikova, A, Dukat, A, Kosmalova, V, Dulkova, K, Dulka, T, Vankova, L, Dzupina, A, Dzupinova, M, Hatalova, K, Hatala, R, Hranai, M, Hofmanova, J, Kasperova, V, Reptova, A, Mazur, J, Pella, D, Fedacko, J, Ruffini, L, Morsky, J, Slanina, M, Kmec, J, Zachar, A, Kokles, M, Zareczky, P, Bollova, D, Badenhorst, J, Erasmus, L, Basson, M, Poynton, M, Allman, J, Ellis, G, Botha, L, Engelbrecht, J, Mostert, M, Essop, M, Nunkoo, T, Gani, M, Wilson, L, Kelfkens, Y, Mitha, I, Taljaard, J, Naidoo, D, Duki, Y, Snyders, F, Munnik, M, Soma, P, Johnston, H, van der Merwe, N, Goosen, Y, van Zyl, L, le Roux, M, Venter, T, Wessels, L, Bae, Hj, Han, Mg, Cha, Jk, Kim, Dh, Cho, Br, Ryu, Dr, Choi, Hh, Chung, W, Oh, Y, Han, Sh, Lee, Kh, Hong, Tj, Lee, Hw, Hyon, M, Jung, Jw, Jeon, Hk, Lee, Jm, Kang, Dh, Choi, Kj, Kim, Cj, Jin, E, Kim, D, Seo, J, Kim, H, Cha, Mj, Kim, Jt, Park, M, Kim, Jh, Park, Jh, Kim, J, Park, Sj, Kim, Sh, Seo, Jb, Kim, Yj, Chun, My, Lee, Mh, Joung, By, Lee, Sh, Shin, Dg, Namgung, J, Kwak, Jj, Rha, Sw, Na, Jo, Rim, Sj, Kim, Jy, Arcocha Torres, M, Rey, Am, Blanco Coronado, J, Puertas, I, Bruguera Cortada, J, Cabero, P, Calvo, C, Calvo, G, de Arce Borda, A, Asensio, A, Diez Tejedor, E, Guevara, Mp, Gonzalez Juanatey, J, Moure, M, Hernandez Madrid, A, Delgado, A, Lopez Garcia Aranda, V, Barquero, R, Manzano, L, Abril, Sb, Merino, J, Diaz Pintado, M, Arias, J, Fernandez, M, Alvarez, Rf, Terns, M, Delgado, Md, Villuendas, R, Astier, L, Appelros, P, Åkerberg, A, Blom, Kb, Andersson, R, Blomström, P, Persson, L, Carlsson, T, Bengtsson, A, Dettmann, S, Östberg, S, Engdahl, J, Karlsson, L, Herlitz, J, Winberg, L, Jernhed, H, Koskinen, P, Håkansson, E, Kozak, P, Edlund, M, Malmqvist, L, Eriksson, G, Randers, F, Moodh, J, Rautio, A, Johansson, M, Rönn, F, Sundholm, C, Stenberg, A, Gunnarsson, A, Thulin, J, Broberg, M, Slater, Ip, Cheng, Cc, Wu, W, Chiang, Ce, Yu, Wc, Chiang, Ft, Wu, Yw, Chiou, Cw, Yeh, Tc, Hsia, Ch, Chen, Yp, Huang, Jl, Chen, Yf, Kuo, Ct, Wang, Cl, Lai, Wt, Lin, Th, Lee, Jt, Pai, Py, Lin, Kh, Shyu, Kg, Chiu, Cz, Tseng, Wk, Pan, Yf, Ueng, Kc, Lee, Sc, Wang, Jh, Tsai, Wc, Yeh, Hi, Kuo, Jy, Jirasirirojanakorn, K, Pornchaiyasit, K, Kaewsuwanna, P, Sinthusopa, W, Kiatchoosakun, S, Sriprasert, S, Laothavorn, P, Bamrungpong, P, Piyayotai, D, Sripracha, A, Panpunuan, P, Sukonthasarn, A, Mekara, W, Vorasettakarnkij, Y, Puripun, E, Acikel, M, Akilli, H, Demir, H, Ata, N, Bayata, S, Cakmak, N, Calik, A, Cayli, M, Ceyhan, C, Erdogan, D, Ermis, C, Kabul, K, Kanadasi, M, Turgut, O, Tandogan, I, Yalcin, R, Yigit, F, Yigit, Z, Zoghi, M, Batushkin, V, Azhdari, M, Bazylevych, A, Vlasyuk, Z, Bereznyakov, I, Lebedynskaya, M, Dotsenko, S, Kulynych, R, Dzyak, G, Vasilyeva, L, Faynyk, A, Sorokivskyy, M, Gavrysyuk, V, Dzublik, Y, Horbach, L, Husyev, V, Godlevska, O, Samburg, Y, Karpenko, O, Nevolina, I, Karpenko, Y, Blihar, O, Kaydashev, I, Gerasimenko, N, Kolomyyits, S, Vasylets, V, Kopytsya, M, Petyunina, O, Kotseruba, V, Dvoieglazova, M, Koval, V, Ohirko, O, Koval', O, Kaplan, P, Kraiz, I, Usan, N, Kraydashenko, O, Stets, R, Kupnovytska, I, Kyyak, Y, Lizogub, V, Gorna, O, Malynovsky, Y, Fedotov, S, Ostrovska, L, Ushakova Sokolova, L, Dovgan, N, Potapenko, P, Nekrasa, A, Prokhorov, O, Leonidova, V, Rebrov, B, Gamachek, O, Rishko, M, Chendey, T, Rudyk, I, Shatilo, V, Ishchuk, V, Shcherbak, V, Goncharova, I, Shvetz, N, Zamlynskyy, M, Sirenko, Y, Stanislavchuk, M, Perebetiuk, L, Sychov, O, Lyzohub, S, Tseluyko, V, Kuznetsov, I, Tykhonova, S, Vakaliuk, I, Drapchak, I, Vatutin, M, Sklyanna, O, Vizir, V, Goncharov, O, Volkov, V, Serik, S, Yagensky, A, Nahrebetskyy, V, Yena, L, Mudruk, I, Zharinov, O, Logvinov, Y, Zhurba, S, Shandra, T, Aggarwal, R, Smith, S, Beeton, I, Dunn, S, Blagden, M, Price, R, Dougal, K, Chapman, O, Davies, D, Choy, A, Duff, J, Cohen, A, Wilmott, R, D'Costa, D, Douglas, H, Dickinson, D, Lie, F, Ramasamy, V, Lindsay, S, Atkinson, C, Linker, N, Finlayson, M, Lip, G, Brown, R, Maccallum, P, Ebano, P, Macleod, M, Mcghee, C, Marazzi, P, Jones, D, Maxwell, T, Isted, C, More, R, Helliwell, L, Moriarty, A, Mackin, A, Murdoch, D, Andrews, A, Newby, D, Flint, L, Pye, M, Wright, L, Avery, D, Young, G, Sopher, M, Kennard, S, Storey, R, Bridge, C, Turner, W, Walker, M, Venkataraman, A, Gilchrist, M, Watkin, R, Chung, A, Wright, A, Wright, J, Abi Mansour, P, Panella, M, Adams, K, Lohman, J, Adler, J, Barash, B, Adler, P, Reiling, S, Beck, P, Ahmad, A, Hussain, A, Ahmadpour, H, Lim, G, Akhter, F, Brubaker, S, Alexander, J, Genova Peeva, E, Aliyar, P, Godsey, W, Allison, J, Biscardi, R, Almquist, A, Macdonald, H, Alsheikh, T, Lane, B, Amin, K, Khetarpal, S, Amin, M, Persechino, F, York, T, Arnold, T, Shoaf, R, Arouni, A, Rasmussen, L, Attanti, S, Strickland, S, Aude, Y, Cobos, D, Awasty, V, Baldwin, E, Ayesu, K, Thompson, B, Baine, S, Batista, M, Baman, R, Campbell, G, Barber, M, Altonen, D, Barker, T, Faircloth, C, Barrington, P, Gordon, L, Bartkowiak, A, Benton, J, Beasley, R, Hoffman, T, Bedoya, R, Luis Valdes, M, Bedwell, N, Craig, M, Beinart, S, Swaim, D, Bensimhon, D, Garman, V, Berk, M, Ibarra, M, Bernard, J, Eldred, R, Bilal, B, Preston, S, Bilazarian, S, Langone, L, Bingham, S, Antonino, M, Block, T, Talbot Lawson, C, Blonder, R, Ensminger, E, Bloomberg, R, Bloomberg, K, Blue, B, Vernon, M, Borsheim, M, Hickenbotham, D, Bouchard, A, Wade, W, Bowden, W, Ziegler, K, Bradley, A, Terry, P, Brilakis, E, Frey, W, Brown, H, Triano, A, Bybee, K, Al Maliky, T, Cader, C, Morton, S, Canaday, D, Canosa, R, Hartranft, E, Caplan, J, Jameson, L, Carr, K, Phan, D, Chang, M, Hatfield, G, Charlat, M, Tamayo, M, Chaturvedi, S, Sawaya, K, Ciaramita, J, Bagby, J, Clapp, T, Clay, A, Mcclelland, M, Dutka, C, Cohen, R, Bossaers, J, Colan, D, Salpas, S, Cole, J, Fisher, M, Concha, M, Martinez, E, Corbett, B, Svadbik, L, Cossu, S, Mullinax, K, Cottiero, R, Masson, E, Cowan, L, Nelson, L, Curtis, B, Sarpola, N, Dang, N, Morgan, T, Daniels, S, Leka, G, Datta, S, Wulf, A, Dave, K, Dave, B, Davuluri, A, Ebreo, N, De Lemos, J, Debes, C, Dean, J, Warmack, D, Degarmo, R, Carey, J, Steward, A, Desire, A, Waters, L, Devenport, S, Briscoe, C, Dhar, S, Ucik, S, Digiovanna, M, Tisdale, L, Donovan, D, Rodriguez, L, Dotani, I, Olson, A, Drozdiak, R, Habibi, S, D'Souza, A, Cullen, T, Eade, J, Dunn, K, Eldadah, Z, Quick, R, Ellis, J, Cristaldi, J, Erenrich, N, Johnson, C, O'Brien, J, Ettinger, N, Shipp, A, Everhart, B, Desalle, D, Fahmy, R, Watkins, D, Feld, L, Tameron, A, Feldman, J, Tang, N, Felten, W, Prior, J, Fialkow, J, Calvo, M, Finkel, M, Shriver, D, Finkelstein, S, Fischell, T, Drew, B, Fishbein, G, Donahue, S, Flores, E, Slayton, C, Forman, S, Solis, A, Frais, M, Thrope, C, Franco, M, Gentry, P, French, W, Morales, C, Friedlander, I, Gaffney, M, Jones, J, Garb, J, Miranda, J, George, F, Valentine, H, Gerber, J, Hinchion, N, Gillespie, E, Keane Richmond, P, Gogia, H, Ewing, B, Goldscher, D, Latteri, J, Goldstein, M, Gowda, S, Rafala, E, Graham, S, Bonora, M, Griffin, S, Aull, L, Griffin, J, Goodman, V, Grossman, C, Davis, A, Grove, D, Mabe, K, Guarino, J, Gabela, W, Guarnieri, T, Guerrero, Foster, B, Guthrie, R, Felsman, D, Gvora, T, Mclean, R, Hack, T, Morelli, L, Hamroff, G, Bentivenga, L, Han, M, Cavanna, L, Harris, J, Bobade, M, Hearne, S, Krater, C, Heiman, M, Dandekar, U, Shah, D, Henderson, D, Millard, D, Henry, S, Harkins, V, Hermany, P, Batchell, K, Herrod, J, Miranda, D, Herson, S, Carey, G, Hinchman, D, Vieira, P, Hippert, R, Dutter, S, Hoekstra, J, Homan, J, Homayouni, A, Horton, K, Sloss, D, Hotchkiss, D, Turner, N, Houchin, V, Howard, V, Hays, D, Howard, L, Craft, D, Huang, P, Truva, C, Hunter, J, Battistelli, E, Hurst, P, Garza, M, Hussain, M, Tambawala, M, Ison, R, Butcher, S, Jardula, M, Andresen, T, Johnson, F, Phillips, T, Jones, R, Hughett, G, Jovin, I, Nichols, M, Judson, P, Royes, A, Kahn, B, Coombs, V, Kai, W, Dugal, J, Kandath, D, Kostedt, G, Kaplan, K, Cook, S, Kapoor, A, Ruggiero, M, Karunaratne, H, Behm, K, Kastelic, R, Davis, C, Keller, R, Keller, J, Kerkering, M, Bartholomaus, D, Kersh, R, Buhler, A, Kesselbrenner, M, Dicorcia, L, Khan, B, Binns, M, Khan, M, Khan, G, Kindman, L, Averett, P, Korpas, D, Godfrey, C, Kotha, P, Sanchez, E, Kozlowski, J, Watts, S, Krichmar, P, Marquez, D, Laliotis, A, Jauregui, V, Lambert, C, Coyle, G, Landau, C, Ferguson, D, Lang, J, Simmons, T, Langevin, E, Faucett, S, Ledbetter, L, Royse, H, Lentz, M, Smith, D, Lesser, M, Hartley, L, Lewis, D, Bonds, C, Lillestol, M, Miller, D, Ling, L, Murphy, R, Littlefield, R, Wofford, E, Lomnitz, D, Lone, B, Davids, M, Looby, R, Ault, S, Lui, H, Wright, H, Lurie, M, Edelstein, J, Macomber, J, Bush, D, Magee, A, Doctor, A, Mainigi, S, Lisiecki, B, Makam, S, Casas, R, Mandviwala, M, Marar, I, Rabadi Marar, D, Marenberg, M, Bedenko, E, Massin, E, Hicks, T, Mccartney, M, Stubbs, L, Mcgarvey, J, Schwarz, L, Mcguire, K, Mckenzie, M, Rodkey, K, Mcknight, T, Paul, J, Mclaurin, B, Lack, A, Mega, J, Marti, J, Meholick, A, Skinner, J, Mehrle, A, Wall, J, Mendelson, R, Cervellione, K, Mercado, A, Cajulis, C, Michlin, B, Romero Colon, J, Milas, J, Sanders, D, Miller, R, Sanchez, S, Miller, S, Gryczan, J, Mody, F, Strugatsky, S, Moran, J, Garner, S, Morledge, J, Bowman, B, Mouhaffel, A, Parrott, N, Mounsey, P, Schuler, C, Mowdy, M, Todd, S, Mullen, P, Raziano, S, Murphy, A, Oehmann, V, Nadar, V, Parker, A, Naidu, J, West, M, Nallasivan, M, Goza, J, Nguyen, T, Nomanee, S, Nielsen, R, Wilmot, M, Oberoi, M, Thakkar, N, Oppenheimer, K, Mccormick, J, Orchard, R, Garcia, L, Osborne, J, Gonzalez, M, Oza, S, Joseph, L, Patnam, S, Dennison, K, Pavon, H, Gorry, N, Pearlstein, R, Montayne, S, Pentz, W, Duncan, D, Peters, P, Chacon, L, Petruzziello, F, Morlando, F, Pettis, K, Brown, F, Pezzella, S, Kirk, D, Poulathas, A, Cush, S, Pratt, R, Neeper, L, Pribble, A, Lowe, K, Pudi, K, Sham, L, Pugeda, J, Ebert, J, Quadrel, M, Rafla, E, Quinlan, E, Reed, C, Quinn, J, Hemmen, C, Rama, P, Domingo, D, Redondo, V, Wroblewski, J, Renzi, M, Stanley, E, Richwine, R, Pazier, P, Riofrio, K, Braun, D, Robinson, J, Cherrico, M, Roehll, W, Hollihan, P, Rosado, Barnhorst, M, Rosado, J, Bamhorst, M, Rosen, R, Martin, C, Ross, S, Freeman, R, Ruoff, G, Nelson, T, Sacco, J, Ball, E, Samal, A, Schomburg, J, Sandberg, J, Lafave, J, Savin, V, Clifton, R, Schaefer, S, Fekete, A, Schneider, R, Schneider, W, Schulman, D, Mercer, S, Seals, A, Ullig, T, Holt, A, Seide, H, Mather, N, Shah, G, Witt, P, Shalaby, A, Seese, M, Shanes, J, Fleets, J, Shaoulian, E, Hren, A, Sheikh, K, Hengerer, T, Shih, H, Browning, J, Shoukfeh, M, Stephenson, L, Siler, T, Champagne, M, Simpson, P, Meyer, R, Singh, N, Turner, K, Singh, V, Nelson, M, Skierka, R, Hughes, B, Keene, R, Smith, R, Hodnett, P, Spangenthal, S, Thomason, L, Sperling, M, Vasquez, E, Spivack, E, Mccartney, P, Staniloae, C, Liu, M, Steljes, A, Cox, C, Struble, R, Vittitow, T, Suresh, D, Frost, J, Swerchowsky, V, Freemyer, D, Szulawski, I, Herwehe, S, Tahirkheli, N, Springer, K, Takata, T, Bruton, T, Talano, J, Leo, L, Tami, L, Corchado, D, Tatarko, M, Swauger, M, Tawney, K, Dastoli, K, Teague, S, Young, K, Tee, H, Mitchell, T, Teixeira, J, Southam, D, Torres, M, Tucker, P, Salas, L, Updegrove, J, Hanna, K, Val Mejias, J, Harrelson, Kg, Vemireddy, D, Cardoza, T, Verma, S, Parsons, T, Vicari, R, Warren, K, Vijay, N, Washam, M, Vossler, M, Kilcup, S, Walsh, R, Renaud, K, Ward, S, Locklear, T, Waxman, F, Sanchez, G, Weiss, R, St Laurent, B, Westcott, J, Williams, D, Gibson, C, Williams, R, Dowling, C, Willis, J, Vongerichten, S, Wood, K, Capasso Gulve, E, Worley, S, Pointer, S, Yarows, S, Sheehan, T, Yasin, M, Yi, J, Dongas, B, Yousuf, K, Zakhary, B, Curtis, S, Zeig, S, Mason, T, Zellner, C, Harden, M, Roper, E, Waseem, M, and Grammer, M.
- Subjects
Male ,Pyridines ,[SDV]Life Sciences [q-bio] ,Embolism ,Kaplan-Meier Estimate ,030204 cardiovascular system & hematology ,chemistry.chemical_compound ,0302 clinical medicine ,Edoxaban ,Atrial Fibrillation ,MESH: Double-Blind Method ,030212 general & internal medicine ,MESH: Warfarin ,Stroke ,MESH: Aged ,MESH: Middle Aged ,Cardiovascular diseases [NCEBP 14] ,Hazard ratio ,General Medicine ,MESH: Follow-Up Studies ,Middle Aged ,3. Good health ,MESH: Atrial Fibrillation ,Cardiovascular Diseases ,Anesthesia ,Cardiology ,Female ,Adult ,Aged ,Anticoagulants ,Double-Blind Method ,Follow-Up Studies ,Hemorrhage ,Humans ,Thiazoles ,Warfarin ,MESH: Hemorrhage ,Andexanet alfa ,medicine.drug ,medicine.medical_specialty ,MESH: Enoxaparin ,MESH: Anticoagulants ,MESH: Stroke ,Dabigatran ,03 medical and health sciences ,Internal medicine ,medicine ,MESH: Kaplan-Meier Estimate ,Rivaroxaban ,MESH: Humans ,business.industry ,MESH: Cardiovascular Diseases ,MESH: Adult ,medicine.disease ,Confidence interval ,MESH: Male ,chemistry ,business ,MESH: Female ,MESH: Embolism - Abstract
Contains fulltext : 125374.pdf (Publisher’s version ) (Open Access) BACKGROUND: Edoxaban is a direct oral factor Xa inhibitor with proven antithrombotic effects. The long-term efficacy and safety of edoxaban as compared with warfarin in patients with atrial fibrillation is not known. METHODS: We conducted a randomized, double-blind, double-dummy trial comparing two once-daily regimens of edoxaban with warfarin in 21,105 patients with moderate-to-high-risk atrial fibrillation (median follow-up, 2.8 years). The primary efficacy end point was stroke or systemic embolism. Each edoxaban regimen was tested for noninferiority to warfarin during the treatment period. The principal safety end point was major bleeding. RESULTS: The annualized rate of the primary end point during treatment was 1.50% with warfarin (median time in the therapeutic range, 68.4%), as compared with 1.18% with high-dose edoxaban (hazard ratio, 0.79; 97.5% confidence interval [CI], 0.63 to 0.99; P
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- 2013
42. P285Comparison of analysis methodologies for net outcome with edoxaban vs warfarin in patients with atrial fibrillation in the ENGAGE AF-TIMI 48 trial
- Author
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Hamershock, R, primary, De Caterina, R, additional, Antman, E, additional, Murphy, S, additional, Ruff, C, additional, Rutman, H, additional, Mercuri, M, additional, Lanz, H, additional, Braunwald, E, additional, and Giugliano, R, additional
- Published
- 2018
- Full Text
- View/download PDF
43. P4808Edoxaban and implantable cardiac device interventions - Insights from the ENGAGE AF-TIMI 48 trial
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Steffel, J, primary, Ruff, C, additional, Braunwald, E, additional, Hamershock, R, additional, Murphy, S, additional, Nieminen, M, additional, Lanz, H, additional, Mercury, M, additional, Peterson, N, additional, Antman, E, additional, and Giugliano, R, additional
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- 2018
- Full Text
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44. Cholesterol And Total Mortality: Need For Larger Trials
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Collins, R., Keech, A., Peto, R., Sleight, P., Kjekshus, J., Wilhelmsen, I., MacMahon, S., Shaw, J., Simes, J., Braunwald, E., Buring, J., Hennekens, C., Pfeffer, M., Sacks, F., Probstfield, J., Yusuf, S., Downs, J. R., Gotto, A., Cobbe, S., Ford, I., and Shepherd, J.
- Published
- 1992
45. Meeting Report: ESC Forum on Drug Eluting Stents European Heart House, Nice, 27-28 September 2007
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Daemen, Joost, Simoons, Maarten L., Wijns, William, Bagust, Adrian, Bos, Gert, Bowen, James M., Braunwald, Eugene, Camenzind, Edoardo, Chevalier, Bernard, DiMario, Carlo, Fajadet, Jean, Gitt, Anselm, Guagliumi, Giulio, Hillege, Hans L., James, Stefan, Jüni, Peter, Kastrati, Adnan, Kloth, Sabine, Kristensen, Steen D., Krucoff, Mitchell, Legrand, Victor, Pfisterer, Matthias, Rothman, Martin, Serruys, Patrick W., Silber, Sigmund, Steg, Philippe G., Tariah, Ibrahim, Wallentin, Lars, Windecker, Stephan W., Aimonetti, A., Allocco, D., Baczynska, A., Bagust, A., Berenger, M., Bos, G., Boam, A., Bowen, J.M., Braunwald, E., Calle, J.P., Camenzind, E., Campo, G., Carlier, S., Chevalier, B., Daemen, J., de Schepper, J., Di Bisceglie, G., DiMario, C., Dobbels, H., Fajadet, J., Farb, A., Ghislain, J.C., Gitt, A., Guagliumi, G., Hellbardt, S., Hillege, H.L., ten Hoedt, R., Isaia, C., James, S., de Jong, P., Jüni, P., Kastrati, A., Klasen, E., Kloth, S., Kristensen, S.D., Krucoff, M., Legrand, V., Lekehal, M., LeNarz, L., Ni Mhullain, F., Nagai, H., Patteet, A., Paunovic, D., Pfisterer, M., Potgieter, A., Purdy, I., Raveau-Landon, C., Rothman, M., Serruys, P.W., Silber, S., Simoons, M.L., Steg, P.G., Tariah, I., Ternstrom, S., Van Wuytswinkel, J., Waliszewski, M., Wallentin, L., Wijns, W., Windecker, S.W., Daemen, Joost, Simoons, Maarten L., Wijns, William, Bagust, Adrian, Bos, Gert, Bowen, James M., Braunwald, Eugene, Camenzind, Edoardo, Chevalier, Bernard, DiMario, Carlo, Fajadet, Jean, Gitt, Anselm, Guagliumi, Giulio, Hillege, Hans L., James, Stefan, Jüni, Peter, Kastrati, Adnan, Kloth, Sabine, Kristensen, Steen D., Krucoff, Mitchell, Legrand, Victor, Pfisterer, Matthias, Rothman, Martin, Serruys, Patrick W., Silber, Sigmund, Steg, Philippe G., Tariah, Ibrahim, Wallentin, Lars, Windecker, Stephan W., Aimonetti, A., Allocco, D., Baczynska, A., Bagust, A., Berenger, M., Bos, G., Boam, A., Bowen, J.M., Braunwald, E., Calle, J.P., Camenzind, E., Campo, G., Carlier, S., Chevalier, B., Daemen, J., de Schepper, J., Di Bisceglie, G., DiMario, C., Dobbels, H., Fajadet, J., Farb, A., Ghislain, J.C., Gitt, A., Guagliumi, G., Hellbardt, S., Hillege, H.L., ten Hoedt, R., Isaia, C., James, S., de Jong, P., Jüni, P., Kastrati, A., Klasen, E., Kloth, S., Kristensen, S.D., Krucoff, M., Legrand, V., Lekehal, M., LeNarz, L., Ni Mhullain, F., Nagai, H., Patteet, A., Paunovic, D., Pfisterer, M., Potgieter, A., Purdy, I., Raveau-Landon, C., Rothman, M., Serruys, P.W., Silber, S., Simoons, M.L., Steg, P.G., Tariah, I., Ternstrom, S., Van Wuytswinkel, J., Waliszewski, M., Wallentin, L., Wijns, W., and Windecker, S.W.
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- 2017
46. Impaired Cardiac Performance in Rats with Long-Term Spontaneous Hypertension
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Pfeffer, J., Pfeffer, M., Fletcher, P., Braunwald, E., and Strauer, Bodo Eckehard, editor
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- 1981
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47. Symposium 'Limiting of Infarct Size'
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Jennings, R. B., Reimer, K. A., Hort, W., Kalbfleisch, H., Frenzel, H., Kübler, W., Röhrig, D., Schuler, G., Schwarz, F., Spieckermann, P. G., Maroko, R. P., Hjalmarson, A., Bussmann, W.-D., Braunwald, E., and Schlegel, Bernhard, editor
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- 1982
- Full Text
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48. Digoxin therapy and mortality following confirmed or suspected myocardial infarction: Experience in the MILIS study
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MILIS Group, Muller, J. E., Turi, Z. G., Stone, P. H., Rude, R. E., Raabe, D. S., Jaffe, A. S., Gold, H. K., Gustafson, N., Poole, W. K., Passamani, E., Braunwald, E., Smith, Thomas W., Erdmann, Erland, editor, Greef, K., editor, and Skou, J. C., editor
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- 1986
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49. Adjuvant Therapy for Coronary Reperfusion in Evolving Acute Myocardial Infarction
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Kloner, R. A., Braunwald, E., Schmutzler, Horst, editor, Rutsch, Wolfgang, editor, and Dougherty, Frank Christopher, editor
- Published
- 1989
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50. Silent Myocardial Ischemia: A Critical Appraisal : International Round Table, Tel Aviv, December 1989
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Kellermann, J.J, Braunwald, E., Kellermann, J.J, and Braunwald, E.
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- Silent myocardial ischemia--Congresses, Coronary Disease--congresses
- Published
- 2015
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