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21. A randomized phase III study comparing pegylated liposomal doxorubicin with capecitabine as first-line chemotherapy in elderly patients with metastatic breast cancer: results of the OMEGA study of the Dutch Breast Cancer Research Group BOOG†

Author

Smorenburg, C. H., de Groot, S. M., van Leeuwen-Stok, A. E., Hamaker, M. E., Wymenga, A. N., de Graaf, H., de Jongh, F. E., Braun, J. J., Los, M., Maartense, E., van Tinteren, H., Nortier, J. W. R., and Seynaeve, C.

Published
2014
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24. Stable Carbon Isotopes δ13C as a Proxy for Characterizing Carbon Sources and Processes in a Small Tropical Headwater Catchment: Nsimi, Cameroon

Author

Nkoue Ndondo, Gustave Raoul, primary, Probst, J.-L., additional, Ndjama, J., additional, Ndam Ngoupayou, Jules Remy, additional, Boeglin, J.-L., additional, Takem, G. E., additional, Brunet, F., additional, Mortatti, J., additional, Gauthier-Lafaye, F., additional, Braun, J.-J., additional, and Ekodeck, G. E., additional

Published
2020
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32. MAGIC and Fermi-LAT gamma-ray results on unassociated HAWC sources

Author

Ahnen, M. L. (M. L.), Ansoldi, S. (S.), Antonelli, L. A. (L. A.), Arcaro, C. (C.), Baack, D. (D.), Babic, A. (A.), Banerjee, B. (B.), Bangale, P. (P.), Barres de Almeida, U. (U.), Barrio, J. A. (J. A.), Becerra Gonzalez, J. (J.), Bednarek, W. (W.), Bernardini, E. (E.), Berse, R. C. (R. Ch.), Berti, A. (A.), Bhattacharyya, W. (W.), Biland, A. (A.), Blanch, O. (O.), Bonnoli, G. (G.), Carosi, R. (R.), Carosi, A. (A.), Ceribella, G. (G.), Chatterjee, A. (A.), Colak, S. M. (S. M.), Colin, P. (P.), Colombo, E. (E.), Contreras, J. L. (J. L.), Cortina, J. (J.), Covino, S. (S.), Cumani, P. (P.), Da Vela, P. (P.), Dazzi, F. (F.), De Angelis, A. (A.), De Lotto, B. (B.), Delfino, M. (M.), Delgado, J. (J.), Di Pierro, F. (F.), Dominguez, A. (A.), Prester, D. D. (D. Dominis), Dorner, D. (D.), Doro, M. (M.), Einecke, S. (S.), Elsaesser, D. (D.), Ramazani, V. F. (V. Fallah), Fernandez-Barra, A. (A.), Fidalgo, D. (D.), Fonseca, M. V. (M. V.), Font, L. (L.), Fruck, C. (C.), Galindo, D. (D.), Garcia Lopez, R. J. (R. J.), Garczarczyk, M. (M.), Gaug, M. (M.), Giammaria, P. (P.), Godinovic, N. (N.), Gora, D. (D.), Guberman, D. (D.), Hadasch, D. (D.), Hahn, A. (A.), Hassan, T. (T.), Hayashida, M. (M.), Herrera, J. (J.), Hose, J. (J.), Hrupec, D. (D.), Ishio, K. (K.), Konno, Y. (Y.), Kubo, H. (H.), Kushida, J. (J.), Kuvezdic, D. (D.), Lelas, D. (D.), Lindfors, E. (E.), Lombardi, S. (S.), Longo, F. (F.), Lopez, M. (M.), Maggio, C. (C.), Majumdar, P. (P.), Makariev, M. (M.), Maneva, G. (G.), Manganaro, M. (M.), Mannheim, K. (K.), Maraschi, L. (L.), Mariotti, M. (M.), Martinez, M. (M.), Masuda, S. (S.), Mazin, D. (D.), Mielke, K. (K.), Minev, M. (M.), Miranda, J. M. (J. M.), Mirzoyan, R. (R.), Moralejo, A. (A.), Moreno, V. (V.), Moretti, E. (E.), Nagayoshi, T. (T.), Neustroev, V. (V.), Niedzwiecki, A. (A.), Nievas Rosillo, M. (M.), Nigro, C. (C.), Nilsson, K. (K.), Ninci, D. (D.), Nishijima, K. (K.), Noda, K. (K.), Nogues, L. (L.), Paiano, S. (S.), Palacio, J. (J.), Paneque, D. (D.), Paoletti, R. (R.), Paredes, J. M. (J. M.), Pedaletti, G. (G.), Peresano, M. (M.), Persic, M. (M.), Moroni, P. G. (P. G. Prada), F'randini, E. (E.), Puljak, I. (I.), Garcia, J. R. (J. R.), Reichardt, I. (I.), Rhode, W. (W.), Ribo, M. (M.), Rico, J. (J.), Righi, C. (C.), Rugliancich, A. (A.), Saito, T. (T.), Satalecka, K. (K.), Schweizer, T. (T.), Sitarek, J. (J.), Snidaric, I. (I.), Sobczynska, D. (D.), Stamerra, A. (A.), Strzys, M. (M.), Suric, T. (T.), Takahashi, M. (M.), Takalo, L. (L.), Tavecchio, F. (F.), Temnikov, P. (P.), Terzic, T. (T.), Teshima, M. (M.), Torres-Alba, N. (N.), Treves, A. (A.), Tsujimoto, S. (S.), Vanzo, G. (G.), Vazquez Acosta, M. (M.), Vovk, I. (I.), Ward, J. E. (J. E.), Will, M. (M.), Zaric, D. (D.), Albert, A. (A.), Alfaro, R. (R.), Alvarez, C. (C.), Arceo, R. (R.), Arteaga-Velazquez, J. C. (J. C.), Avila Rojas, D. (D.), Solares, H. A. (H. A. Ayala), Becerri, A. (A.), Behnont-Moreno, E. (E.), BenZvi, S. Y. (S. Y.), Berna, A. (A.), Braun, J. (J.), Caballero-Mora, K. S. (K. S.), Capistran, T. (T.), Carraminana, A. (A.), Casanova, S. (S.), Castillo, M. (M.), Cotti, U. (U.), Cotzomi, J. (J.), Coutino de Leon, S. (S.), De Leon, C. (C.), De la Fuente, E. (E.), Diaz Hernandez, R. (R.), Dichiara, S. (S.), Dingus, B. L. (B. L.), DuVernois, M. A. (M. A.), Diaz-Velez, J. C. (J. C.), Ellsworth, R. W. (R. W.), Engel, K. (K.), Enriquez-Rivera, O. (O.), Fiorino, D. W. (D. W.), Fleischhack, H. (H.), Fraija, N. (N.), Garcia-Gonzalez, J. A. (J. A.), Garfias, F. (F.), Gonzalez-Munoz, A. (A.), Gonzalez, M. M. (M. M.), Goodman, J. A. (J. A.), Hampel-Arias, Z. (Z.), Harding, J. P. (J. P.), Hernandez, S. (S.), Hueyotl-Zahuantitla, F. (F.), Hui, C. M. (C. M.), Huntemeyer, P. (P.), Iriarte, A. (A.), Jardin-Blicq, A. (A.), Joshi, V. (V.), Kaufmann, S. (S.), Lara, A. (A.), Lauer, R. J. (R. J.), Lee, W. H. (W. H.), Lennarz, D. (D.), Leon Vargas, H. (H.), Linnemann, J. T. (J. T.), Longinotti, A. L. (A. L.), Luis-Raya, G. (G.), Luna-Garcia, R. (R.), Lopez-Coto, R. (R.), Malone, K. (K.), Marinelli, S. S. (S. S.), Martinez, O. (O.), Martinez-Castellanos, I. (I.), Martinez-Castro, J. (J.), Martinez-Huerta, H. (H.), Matthews, J. A. (J. A.), Miranda-Romagnoli, P. (P.), Moreno, E. (E.), Mostafa, M. (M.), Nayerhoda, A. (A.), Nellen, L. (L.), Newbold, M. (M.), Nisa, M. U. (M. U.), Noriega-Papaqui, R. (R.), Pelayo, R. (R.), Pretz, J. (J.), Perez-Perez, E. G. (E. G.), Ren, Z. (Z.), Rho, C. D. (C. D.), Riviere, C. (C.), Rosa-Gonzalez, D. (D.), Rosenberg, M. (M.), Ruiz-Velasco, E. (E.), Greus, F. S. (F. Salesa), Sandoval, A. (A.), Schneider, M. (M.), Arroyo, M. S. (M. Seglar), Sinnis, G. (G.), Smith, A. J. (A. J.), Springer, R. W. (R. W.), Surajbali, P. (P.), Taboada, I. (I.), Tibolla, O. (O.), Tollefson, K. (K.), Torres, I. (I.), Ukwatta, T. N. (T. N.), Vianello, G. (G.), Villasenor, L. (L.), Werner, F. (F.), Westerhoff, S. (S.), Wood, J. (J.), Yapici, T. (T.), Yodh, G. (G.), Zepeda, A. (A.), Zhou, H. (H.), Alvarez, J. D. (J. D.), Ajello, M. (M.), Baldini, L. (L.), Barbiellini, G. (G.), Berenji, B. (B.), Bissaldi, E. (E.), Blandford, R. D. (R. D.), Bonino, R. (R.), Bottacini, E. (E.), Brandt, T. J. (T. J.), Bregeon, J. (J.), Brue, P. (P.), Cameron, R. A. (R. A.), Caputo, R. (R.), Caraveo, P. A. (P. A.), Castro, D. (D.), Cavazzuti, E. (E.), Chiaro, G. (G.), Ciprini, S. (S.), Costantin, D. (D.), D'Ammando, F. (F.), de Palma, F. (F.), Desai, A. (A.), Di Lalla, N. (N.), Di Mauro, M. (M.), Di Venere, L. (L.), Favuzzi, C. (C.), Fukazawa, Y. (Y.), Funk, S. (S.), Fusco, P. (P.), Gargano, F. (F.), Gasparrini, D. (D.), Giglietto, N. (N.), Giordano, F. (F.), Giroletti, M. (M.), Glanzman, T. (T.), Green, D. (D.), Grenier, I. A. (I. A.), Guiriec, S. (S.), Harding, A. K. (A. K.), Hays, E. (E.), Hewitt, J. W. (J. W.), Horan, D. (D.), Johannesson, G. (G.), Kuss, M. (M.), Larsson, S. (S.), Liodakis, i. (i), Loparco, F. (F.), Lubrano, P. (P.), Magill, J. D. (J. D.), Maldera, S. (S.), Manfreda, A. (A.), Mazziotta, M. N. (M. N.), Mereu, I. (I.), Michelson, R. F. (R. F.), Mizuno, T. (T.), Monzani, M. E. (M. E.), Morselli, A. (A.), Moskalenko, I. V. (I. V.), Negro, M. (M.), Nuss, E. (E.), Omodei, N. (N.), Orienti, M. (M.), Orlando, E. (E.), Ormes, J. F. (J. F.), Palatiello, M. (M.), Paliya, V. S. (V. S.), Pesce-Rollins, M. (M.), Petrosian, V. (V.), Piron, F. (F.), Porter, T. A. (T. A.), Principe, G. (G.), Raino, S. (S.), Rani, B. (B.), Razzano, M. (M.), Razzaque, S. (S.), Reimer, A. (A.), Reimer, O. (O.), Sgro, C. (C.), Siskind, E. J. (E. J.), Spandre, G. (G.), Spinelli, P. (P.), Tajima, H. (H.), Thayer, J. B. (J. B.), Thompson, D. J. (D. J.), Torres, D. F. (D. F.), Torresi, E. (E.), Troja, E. (E.), Valverde, J. (J.), Wood, K. (K.), Yassine, M. (M.), Ahnen, M. L. (M. L.), Ansoldi, S. (S.), Antonelli, L. A. (L. A.), Arcaro, C. (C.), Baack, D. (D.), Babic, A. (A.), Banerjee, B. (B.), Bangale, P. (P.), Barres de Almeida, U. (U.), Barrio, J. A. (J. A.), Becerra Gonzalez, J. (J.), Bednarek, W. (W.), Bernardini, E. (E.), Berse, R. C. (R. Ch.), Berti, A. (A.), Bhattacharyya, W. (W.), Biland, A. (A.), Blanch, O. (O.), Bonnoli, G. (G.), Carosi, R. (R.), Carosi, A. (A.), Ceribella, G. (G.), Chatterjee, A. (A.), Colak, S. M. (S. M.), Colin, P. (P.), Colombo, E. (E.), Contreras, J. L. (J. L.), Cortina, J. (J.), Covino, S. (S.), Cumani, P. (P.), Da Vela, P. (P.), Dazzi, F. (F.), De Angelis, A. (A.), De Lotto, B. (B.), Delfino, M. (M.), Delgado, J. (J.), Di Pierro, F. (F.), Dominguez, A. (A.), Prester, D. D. (D. Dominis), Dorner, D. (D.), Doro, M. (M.), Einecke, S. (S.), Elsaesser, D. (D.), Ramazani, V. F. (V. Fallah), Fernandez-Barra, A. (A.), Fidalgo, D. (D.), Fonseca, M. V. (M. V.), Font, L. (L.), Fruck, C. (C.), Galindo, D. (D.), Garcia Lopez, R. J. (R. J.), Garczarczyk, M. (M.), Gaug, M. (M.), Giammaria, P. (P.), Godinovic, N. (N.), Gora, D. (D.), Guberman, D. (D.), Hadasch, D. (D.), Hahn, A. (A.), Hassan, T. (T.), Hayashida, M. (M.), Herrera, J. (J.), Hose, J. (J.), Hrupec, D. (D.), Ishio, K. (K.), Konno, Y. (Y.), Kubo, H. (H.), Kushida, J. (J.), Kuvezdic, D. (D.), Lelas, D. (D.), Lindfors, E. (E.), Lombardi, S. (S.), Longo, F. (F.), Lopez, M. (M.), Maggio, C. (C.), Majumdar, P. (P.), Makariev, M. (M.), Maneva, G. (G.), Manganaro, M. (M.), Mannheim, K. (K.), Maraschi, L. (L.), Mariotti, M. (M.), Martinez, M. (M.), Masuda, S. (S.), Mazin, D. (D.), Mielke, K. (K.), Minev, M. (M.), Miranda, J. M. (J. M.), Mirzoyan, R. (R.), Moralejo, A. (A.), Moreno, V. (V.), Moretti, E. (E.), Nagayoshi, T. (T.), Neustroev, V. (V.), Niedzwiecki, A. (A.), Nievas Rosillo, M. (M.), Nigro, C. (C.), Nilsson, K. (K.), Ninci, D. (D.), Nishijima, K. (K.), Noda, K. (K.), Nogues, L. (L.), Paiano, S. (S.), Palacio, J. (J.), Paneque, D. (D.), Paoletti, R. (R.), Paredes, J. M. (J. M.), Pedaletti, G. (G.), Peresano, M. (M.), Persic, M. (M.), Moroni, P. G. (P. G. Prada), F'randini, E. (E.), Puljak, I. (I.), Garcia, J. R. (J. R.), Reichardt, I. (I.), Rhode, W. (W.), Ribo, M. (M.), Rico, J. (J.), Righi, C. (C.), Rugliancich, A. (A.), Saito, T. (T.), Satalecka, K. (K.), Schweizer, T. (T.), Sitarek, J. (J.), Snidaric, I. (I.), Sobczynska, D. (D.), Stamerra, A. (A.), Strzys, M. (M.), Suric, T. (T.), Takahashi, M. (M.), Takalo, L. (L.), Tavecchio, F. (F.), Temnikov, P. (P.), Terzic, T. (T.), Teshima, M. (M.), Torres-Alba, N. (N.), Treves, A. (A.), Tsujimoto, S. (S.), Vanzo, G. (G.), Vazquez Acosta, M. (M.), Vovk, I. (I.), Ward, J. E. (J. E.), Will, M. (M.), Zaric, D. (D.), Albert, A. (A.), Alfaro, R. (R.), Alvarez, C. (C.), Arceo, R. (R.), Arteaga-Velazquez, J. C. (J. C.), Avila Rojas, D. (D.), Solares, H. A. (H. A. Ayala), Becerri, A. (A.), Behnont-Moreno, E. (E.), BenZvi, S. Y. (S. Y.), Berna, A. (A.), Braun, J. (J.), Caballero-Mora, K. S. (K. S.), Capistran, T. (T.), Carraminana, A. (A.), Casanova, S. (S.), Castillo, M. (M.), Cotti, U. (U.), Cotzomi, J. (J.), Coutino de Leon, S. (S.), De Leon, C. (C.), De la Fuente, E. (E.), Diaz Hernandez, R. (R.), Dichiara, S. (S.), Dingus, B. L. (B. L.), DuVernois, M. A. (M. A.), Diaz-Velez, J. C. (J. C.), Ellsworth, R. W. (R. W.), Engel, K. (K.), Enriquez-Rivera, O. (O.), Fiorino, D. W. (D. W.), Fleischhack, H. (H.), Fraija, N. (N.), Garcia-Gonzalez, J. A. (J. A.), Garfias, F. (F.), Gonzalez-Munoz, A. (A.), Gonzalez, M. M. (M. M.), Goodman, J. A. (J. A.), Hampel-Arias, Z. (Z.), Harding, J. P. (J. P.), Hernandez, S. (S.), Hueyotl-Zahuantitla, F. (F.), Hui, C. M. (C. M.), Huntemeyer, P. (P.), Iriarte, A. (A.), Jardin-Blicq, A. (A.), Joshi, V. (V.), Kaufmann, S. (S.), Lara, A. (A.), Lauer, R. J. (R. J.), Lee, W. H. (W. H.), Lennarz, D. (D.), Leon Vargas, H. (H.), Linnemann, J. T. (J. T.), Longinotti, A. L. (A. L.), Luis-Raya, G. (G.), Luna-Garcia, R. (R.), Lopez-Coto, R. (R.), Malone, K. (K.), Marinelli, S. S. (S. S.), Martinez, O. (O.), Martinez-Castellanos, I. (I.), Martinez-Castro, J. (J.), Martinez-Huerta, H. (H.), Matthews, J. A. (J. A.), Miranda-Romagnoli, P. (P.), Moreno, E. (E.), Mostafa, M. (M.), Nayerhoda, A. (A.), Nellen, L. (L.), Newbold, M. (M.), Nisa, M. U. (M. U.), Noriega-Papaqui, R. (R.), Pelayo, R. (R.), Pretz, J. (J.), Perez-Perez, E. G. (E. G.), Ren, Z. (Z.), Rho, C. D. (C. D.), Riviere, C. (C.), Rosa-Gonzalez, D. (D.), Rosenberg, M. (M.), Ruiz-Velasco, E. (E.), Greus, F. S. (F. Salesa), Sandoval, A. (A.), Schneider, M. (M.), Arroyo, M. S. (M. Seglar), Sinnis, G. (G.), Smith, A. J. (A. J.), Springer, R. W. (R. W.), Surajbali, P. (P.), Taboada, I. (I.), Tibolla, O. (O.), Tollefson, K. (K.), Torres, I. (I.), Ukwatta, T. N. (T. N.), Vianello, G. (G.), Villasenor, L. (L.), Werner, F. (F.), Westerhoff, S. (S.), Wood, J. (J.), Yapici, T. (T.), Yodh, G. (G.), Zepeda, A. (A.), Zhou, H. (H.), Alvarez, J. D. (J. D.), Ajello, M. (M.), Baldini, L. (L.), Barbiellini, G. (G.), Berenji, B. (B.), Bissaldi, E. (E.), Blandford, R. D. (R. D.), Bonino, R. (R.), Bottacini, E. (E.), Brandt, T. J. (T. J.), Bregeon, J. (J.), Brue, P. (P.), Cameron, R. A. (R. A.), Caputo, R. (R.), Caraveo, P. A. (P. A.), Castro, D. (D.), Cavazzuti, E. (E.), Chiaro, G. (G.), Ciprini, S. (S.), Costantin, D. (D.), D'Ammando, F. (F.), de Palma, F. (F.), Desai, A. (A.), Di Lalla, N. (N.), Di Mauro, M. (M.), Di Venere, L. (L.), Favuzzi, C. (C.), Fukazawa, Y. (Y.), Funk, S. (S.), Fusco, P. (P.), Gargano, F. (F.), Gasparrini, D. (D.), Giglietto, N. (N.), Giordano, F. (F.), Giroletti, M. (M.), Glanzman, T. (T.), Green, D. (D.), Grenier, I. A. (I. A.), Guiriec, S. (S.), Harding, A. K. (A. K.), Hays, E. (E.), Hewitt, J. W. (J. W.), Horan, D. (D.), Johannesson, G. (G.), Kuss, M. (M.), Larsson, S. (S.), Liodakis, i. (i), Loparco, F. (F.), Lubrano, P. (P.), Magill, J. D. (J. D.), Maldera, S. (S.), Manfreda, A. (A.), Mazziotta, M. N. (M. N.), Mereu, I. (I.), Michelson, R. F. (R. F.), Mizuno, T. (T.), Monzani, M. E. (M. E.), Morselli, A. (A.), Moskalenko, I. V. (I. V.), Negro, M. (M.), Nuss, E. (E.), Omodei, N. (N.), Orienti, M. (M.), Orlando, E. (E.), Ormes, J. F. (J. F.), Palatiello, M. (M.), Paliya, V. S. (V. S.), Pesce-Rollins, M. (M.), Petrosian, V. (V.), Piron, F. (F.), Porter, T. A. (T. A.), Principe, G. (G.), Raino, S. (S.), Rani, B. (B.), Razzano, M. (M.), Razzaque, S. (S.), Reimer, A. (A.), Reimer, O. (O.), Sgro, C. (C.), Siskind, E. J. (E. J.), Spandre, G. (G.), Spinelli, P. (P.), Tajima, H. (H.), Thayer, J. B. (J. B.), Thompson, D. J. (D. J.), Torres, D. F. (D. F.), Torresi, E. (E.), Troja, E. (E.), Valverde, J. (J.), Wood, K. (K.), and Yassine, M. (M.)

Abstract

The HAWC Collaboration released the 2HWC catalogue of TeV sources, in which 19 show no association with any known high-energy (HE; E ≳ 10 GeV) or very-high-energy (VHE; E ≳ 300 GeV) sources. This catalogue motivated follow-up studies by both the Major Atmospheric Gamma-ray Imaging Cherenkov (MAGIC) and Fermi-LAT (Large Area Telescope) observatories with the aim of investigating gamma-ray emission over a broad energy band. In this paper, we report the results from the first joint work between High Altitude Water Cherenkov (HAWC), MAGIC, and Fermi-LAT on three unassociated HAWC sources: 2HWC J2006+341, 2HWC J1907+084*, and 2HWC J1852+013*. Although no significant detection was found in the HE and VHE regimes, this investigation shows that a minimum 1° extension (at 95 per cent confidence level) and harder spectrum in the GeV than the one extrapolated from HAWC results are required in the case of 2HWC J1852+013*, whilst a simply minimum extension of 0.16° (at 95 per cent confidence level) can already explain the scenario proposed by HAWC for the remaining sources. Moreover, the hypothesis that these sources are pulsar wind nebulae is also investigated in detail.

Published
2019

35. OZCAR: The French Network of Critical Zone Observatories

Author

Gaillardet, J., primary, Braud, I., additional, Hankard, F., additional, Anquetin, S., additional, Bour, O., additional, Dorfliger, N., additional, de Dreuzy, J.R., additional, Galle, S., additional, Galy, C., additional, Gogo, S., additional, Gourcy, L., additional, Habets, F., additional, Laggoun, F., additional, Longuevergne, L., additional, Le Borgne, T., additional, Naaim-Bouvet, F., additional, Nord, G., additional, Simonneaux, V., additional, Six, D., additional, Tallec, T., additional, Valentin, C., additional, Abril, G., additional, Allemand, P., additional, Arènes, A., additional, Arfib, B., additional, Arnaud, L., additional, Arnaud, N., additional, Arnaud, P., additional, Audry, S., additional, Comte, V. Bailly, additional, Batiot, C., additional, Battais, A., additional, Bellot, H., additional, Bernard, E., additional, Bertrand, C., additional, Bessière, H., additional, Binet, S., additional, Bodin, J., additional, Bodin, X., additional, Boithias, L., additional, Bouchez, J., additional, Boudevillain, B., additional, Moussa, I. Bouzou, additional, Branger, F., additional, Braun, J. J., additional, Brunet, P., additional, Caceres, B., additional, Calmels, D., additional, Cappelaere, B., additional, Celle-Jeanton, H., additional, Chabaux, F., additional, Chalikakis, K., additional, Champollion, C., additional, Copard, Y., additional, Cotel, C., additional, Davy, P., additional, Deline, P., additional, Delrieu, G., additional, Demarty, J., additional, Dessert, C., additional, Dumont, M., additional, Emblanch, C., additional, Ezzahar, J., additional, Estèves, M., additional, Favier, V., additional, Faucheux, M., additional, Filizola, N., additional, Flammarion, P., additional, Floury, P., additional, Fovet, O., additional, Fournier, M., additional, Francez, A. J., additional, Gandois, L., additional, Gascuel, C., additional, Gayer, E., additional, Genthon, C., additional, Gérard, M. F., additional, Gilbert, D., additional, Gouttevin, I., additional, Grippa, M., additional, Gruau, G., additional, Jardani, A., additional, Jeanneau, L., additional, Join, J. L., additional, Jourde, H., additional, Karbou, F., additional, Labat, D., additional, Lagadeuc, Y., additional, Lajeunesse, E., additional, Lastennet, R., additional, Lavado, W., additional, Lawin, E., additional, Lebel, T., additional, Le Bouteiller, C., additional, Legout, C., additional, Lejeune, Y., additional, Le Meur, E., additional, Le Moigne, N., additional, Lions, J., additional, Lucas, A., additional, Malet, J. P., additional, Marais-Sicre, C., additional, Maréchal, J. C., additional, Marlin, C., additional, Martin, P., additional, Martins, J., additional, Martinez, J. M., additional, Massei, N., additional, Mauclerc, A., additional, Mazzilli, N., additional, Molénat, J., additional, Moreira-Turcq, P., additional, Mougin, E., additional, Morin, S., additional, Ngoupayou, J. Ndam, additional, Panthou, G., additional, Peugeot, C., additional, Picard, G., additional, Pierret, M. C., additional, Porel, G., additional, Probst, A., additional, Probst, J. L., additional, Rabatel, A., additional, Raclot, D., additional, Ravanel, L., additional, Rejiba, F., additional, René, P., additional, Ribolzi, O., additional, Riotte, J., additional, Rivière, A., additional, Robain, H., additional, Ruiz, L., additional, Sanchez-Perez, J. M., additional, Santini, W., additional, Sauvage, S., additional, Schoeneich, P., additional, Seidel, J. L., additional, Sekhar, M., additional, Sengtaheuanghoung, O., additional, Silvera, N., additional, Steinmann, M., additional, Soruco, A., additional, Tallec, G., additional, Thibert, E., additional, Lao, D. Valdes, additional, Vincent, C., additional, Viville, D., additional, Wagnon, P., additional, and Zitouna, R., additional

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2018
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36. Safety and tolerability of subcutaneous trastuzumab for the adjuvant treatment of human epidermal growth factor receptor 2-positive early breast cancer: SafeHer phase III study's primary analysis of 2573 patients

Author

Gligorov, J, Ataseven, B, Verrill, M, de Laurentiis, M, Jung, K, Azim, H, Al-Sakaff, N, Lauer, S, Shing, M, Pivot, X, Koroveshi, D, Bouzid, K, Casalnuovo, M, Cascallar, D, Korbenfeld, E, Bastick, P, Beith, J, Colosimo, M, Friedlander, M, Ganju, V, Green, M, Patterson, K, Redfern, A, Richardson, G, Ceric, T, Gordana, K, Beato, C, Ferrari, M, Hegg, R, Helena, V, Ismael, G, Lessa, A, Mano, M, Morelle, A, Nogueira, J, Timcheva, K, Tomova, A, Tsakova, M, Zlatareva-Petrova, A, Asselah, J, Assi, H, Brezden-Masley, C, Chia, S, Freedman, O, Harb, M, Joy, A, Kulkarni, S, Prady, C, Gaete, A, Matamala, L, Torres, R, Yanez, E, Franco, S, Urrego, M, Gugic, D, Vrbanec, D, Melichar, B, Prausova, J, Vyzula, R, Pilarte, R, Leon, M, Munoz, R, Ramos, G, Azeem, H, Aziz, A, El Zawahry, H, Osegueda, F, Alexandre, J, Artignan, X, Barletta, H, Beguier, E, Berdah, J, Marty, C, Bollet, M, Bourgeois, H, Bressac, C, Burki, F, Campone, M, Coeffic, D, Cojocarasu, O, Dagada, C, Dalenc, F, Del Piano, F, Desauw, C, Desmoulins, I, Dohollou, N, Egreteau, J, Ferrero, J, Foa, C, Garidi, R, Gasnault, L, Guardiola, E, Hamizi, S, Jarcau, R, Jacquin, J, Jaubert, D, Jolimoy, G, Mineur, H, Largillier, R, Leduc, B, Martin, P, Melis, A, Monge, J, Moullet, I, Mousseau, M, Nguyen, S, Orfeuvre, H, Petit, T, Priou, F, Bach, I, Simon, H, Stefani, L, Uwer, L, Youssef, A, Aktas, B, von der Assen, A, Augustin, D, Balser, C, Bauer, L, Bechtner, C, Beyer, G, Brucker, C, Buckner, U, Busch, S, Christensen, B, Deryal, M, Farrokh, A, Faust, E, Friedrichs, K, Graf, H, Griesshammer, M, Grischke, E, Hanle, C, Heider, A, Henschen, S, Hesse, T, Jackisch, C, Kisro, J, Kohler, A, Kuemmel, S, Lampe, D, Lantzsch, T, Latos, K, Lex, B, Liedtke, C, Luedders, D, Maintz, C, Muller, V, Overkamp, F, Park-Simon, T, Paul, M, Prechtl, A, Ringsdorf, U, Runnebaum, I, Ruth, S, Salat, C, Scheffen, I, Schilling, J, Schmatloch, S, Schmidt, M, Schneeweiss, A, Schrader, I, Seipelt, G, Simon, E, Stefek, A, Stickeler, E, Thill, M, Tio, J, Tuczek, A, Warm, M, Weigel, M, Wischnik, A, Wojcinski, S, Ziegler-Lohr, K, Aravantinos, G, Ardavanis, A, Fountzilas, G, Gogas, H, Kakolyris, S, Mavroudis, D, Papadimitriou, C, Papandreou, C, Papazisis, K, Castro, H, Hernandez-Monroy, C, Ngan, R, Yeo, W, Bittner, N, Boer, K, Csejtei, A, Horvath, Z, Kocsis, J, Mangel, L, Mezei, K, Nagy, Z, Szanto, J, Atmakusuma, D, Fadjari, H, Kurnianda, D, Prayogo, N, Tanggo, E, Coate, L, Hennessy, B, Kelly, C, Martin, M, Nasim, S, O'Connor, M, Aieta, M, Allegrini, G, Amadori, D, Bidoli, P, Biti, G, Bordonaro, R, Bottini, A, Carterni, G, Cavanna, L, Cazzaniga, M, Cognetti, F, Contu, A, Cruciani, G, Donadio, M, Falcone, A, Farci, D, Forcignano, R, Frassoldati, A, Gaion, F, Gamucci, T, Giotta, F, Livi, L, Lorusso, V, Maiello, E, Marchetti, P, Mariani, G, Mion, M, Moscetti, L, Musolino, A, Pazzola, A, Pedrazzoli, P, Pigi, A, de Placido, S, Caremoli, E, Santoro, A, Tienghi, A, Ahn, J, Lee, K, Lee, S, Seo, J, Sohn, J, Cesas, A, Juozaityte, E, Cheah, N, Chong, F, Devi, B, Phua, V, Teoh, D, Ching, L, Yusof, M, Corona, J, Dominguez, A, Mendoza, R, Hernandez, C, Ramiro, A, Santos, J, Espinosa, P, Villarreal Garza, C, Errihani, H, Bakker, S, van den Berkmortel, F, Blaisse, R, Huinink, D, van den Bosch, J, Braun, J, Dercksen, M, Droogendijk, H, Erdkamp, F, Haringhuizen, A, de Jongh, F, Kok, T, Los, M, Madretsma, S, Terwogt, J, van der Padt, A, van Rossum-Schornagel, Q, Smilde, T, de Valk, B, van der Velden, A, van Warmerdam, L, van de Wouw, A, North, R, Kersten, C, Mjaaland, I, Wist, E, Aziz, Z, Masood, N, Rashid, K, Shah, M, Alcedo, J, Aleman, D, Neciosup, S, Reategui, R, Valdiviezo, N, Vera, L, Fernando, G, Roque, F, Strebel, H, Krzemieniecki, K, Litwiniuk, M, Mruk, A, Pienkowski, T, Sawrycki, P, Slomian, G, Tomczak, P, Afonso, N, Cardoso, F, Damasceno, M, Nave, M, Badulescu, F, Ciule, L, Curescu, S, Eniu, A, Filip, D, Grecea, D, Jinga, D, Lungulescu, D, Oprean, C, Stanculeanu, D, Turdean, M, Dvornichenko, V, Emelyanov, S, Lichinitser, M, Manikhas, A, Sakaeva, D, Shirinkin, V, Stroyakovskiy, D, Abulkhair, O, Zekri, J, Filipovic, S, Kovcin, V, Nedovic, J, Pesic, J, Vasovic, S, Ng, R, Bystricky, B, Leskova, J, Mardiak, J, Misurova, E, Wagnerova, M, Takac, I, Demetriou, G, Dreosti, L, Govender, P, Jordaan, J, Veersamy, P, Romero, J, Lopez, N, Arias, C, Chacon, J, Aramburo, A, Morales, L, Garcia, M, Estevez, L, Garcia-Palomo Perez, A, Garcia Saenz, J, Garcia Sanchis, L, Cubells, L, Cortijo, L, Santiago, S, De Aranguiz, B, Manas, J, Gallego, P, Cussac, A, Ferrandiz, C, Garrido, M, Alvarez, P, Vega, J, Del Prado, P, Janez, N, Murillo, S, Rosales, A, Jaso, L, Fernandez, I, Martorell, A, Carrion, R, Simon, S, Alcibar, A, Lorenzo, J, Garcia, V, Asensio, T, Maicas, M, Villanueva Silva, M, Killander, F, Svensson, J, Fehr, M, Hauser, N, Muller, A, Pagani, O, Passmann-Kegel, H, Popescu, R, Rabaglio, M, Rauch, D, Schlatter, C, Zaman, K, Chang, T, Huang, C, Wang, H, Yu, J, Bandidwattanawong, C, Maneechavakajorn, J, Seetalarom, K, Dejthevaporn, T, Somwangprasert, A, Vongsaisuwon, M, Akbulut, H, Altundag, K, Arican, A, Bozcuk, H, Eralp, Y, Idris, M, Isikdogan, A, Senol, C, Sevinc, A, Uygun, K, Yucel, E, Yucel, I, Yumuk, F, Shparyk, Y, Voitko, N, Jaloudi, M, Adams, J, Agrawal, R, Ahmed, S, Alhasso, A, Allerton, R, Anwar, S, Archer, C, Ashford, R, Barraclough, L, Bertelli, G, Bishop, J, Branson, T, Butt, M, Chakrabarti, A, Chakraborti, P, Churn, M, Crowley, C, Davis, R, Dhadda, A, Eldeeb, H, Fraser, J, Hall, J, Hickish, T, Hogg, M, Howe, T, Joffe, J, Kelleher, M, Kelly, S, Kendall, A, Kristeleit, H, Lumsden, G, Macmillan, C, Macpherson, I, Malik, Z, Mithal, N, Neal, A, Panwar, U, Proctor, A, Proctor, S, Raj, S, Rehman, S, Sandri, I, Scatchard, K, Sherwin, E, Sims, E, Singer, J, Smith, S, Tahir, S, Taylor, W, Tsalic, M, Wardley, A, Waters, S, Wheatley, D, Wright, K, Yuille, F, Alonso, I, Artagaveytia, N, Rodriguez, R, Arbona, E, Garcia, Y, Lion, L, Marcano, D, Van Thuan, T, Gligorov J., Ataseven B., Verrill M., de Laurentiis M., Jung K. H., Azim H. A., Al-Sakaff N., Lauer S., Shing M., Pivot X., Koroveshi D., Bouzid K., Casalnuovo M., Cascallar D., Korbenfeld E. P., Bastick P., Beith J., Colosimo M., Friedlander M., Ganju V., Green M., Patterson K., Redfern A., Richardson G., Ceric T., Gordana K., Beato C. A., Ferrari M., Hegg R., Helena V., Ismael G. F., Lessa A. E., Mano M., Morelle A., Nogueira J. A., Timcheva K., Tomova A., Tsakova M., Zlatareva-Petrova A., Asselah J., Assi H., Brezden-Masley C., Chia S., Freedman O., Harb M., Joy A. A., Kulkarni S., Prady C., Gaete A. A. A., Matamala L., Torres R., Yanez E., Franco S., Urrego M., Gugic D., Vrbanec D., Melichar B., Prausova J., Vyzula R., Pilarte R. G., Leon M. I., Munoz R., Ramos G., Azeem H. A., Aziz A. A., El Zawahry H., Osegueda F. R., Alexandre J., Artignan X., Barletta H., Beguier E., Berdah J. -F., Marty C. B., Bollet M., Bourgeois H., Bressac C., Burki F., Campone M., Coeffic D., Cojocarasu O. Z., Dagada C., Dalenc F., Del Piano F., Desauw C., Desmoulins I., Dohollou N., Egreteau J., Ferrero J. -M., Foa C., Garidi R., Gasnault L., Guardiola E., Hamizi S., Jarcau R., Jacquin J. -P., Jaubert D., Jolimoy G., Mineur H. L., Largillier R., Leduc B., Martin P., Melis A., Monge J., Moullet I., Mousseau M., Nguyen S., Orfeuvre H., Petit T., Priou F., Bach I. S., Simon H., Stefani L., Uwer L., Youssef A., Aktas B., von der Assen A., Augustin D., Balser C., Bauer L. -E., Bechtner C., Beyer G., Brucker C., Buckner U., Busch S., Christensen B., Deryal M., Farrokh A., Faust E., Friedrichs K., Graf H., Griesshammer M., Grischke E. -M., Hanle C., Heider A., Henschen S., Hesse T., Jackisch C., Kisro J., Kohler A., Kuemmel S., Lampe D., Lantzsch T., Latos K., Lex B., Liedtke C., Luedders D., Maintz C., Muller V., Overkamp F., Park-Simon T. -W., Paul M., Prechtl A., Ringsdorf U., Runnebaum I., Ruth S., Salat C., Scheffen I., Schilling J., Schmatloch S., Schmidt M., Schneeweiss A., Schrader I., Seipelt G., Simon E., Stefek A., Stickeler E., Thill M., Tio J., Tuczek A., Warm M., Weigel M., Wischnik A., Wojcinski S., Ziegler-Lohr K., Aravantinos G., Ardavanis A., Fountzilas G., Gogas H., Kakolyris S., Mavroudis D., Papadimitriou C., Papandreou C., Papazisis K., Castro H., Hernandez-Monroy C. E., Ngan R., Yeo W., Bittner N., Boer K., Csejtei A., Horvath Z., Kocsis J., Mangel L. C., Mezei K., Nagy Z., Szanto J., Atmakusuma D., Fadjari H., Kurnianda D., Prayogo N., Tanggo E. H., Coate L., Hennessy B., Kelly C., Martin M., Nasim S., O'Connor M., Aieta M., Allegrini G., Amadori D., Bidoli P., Biti G., Bordonaro R., Bottini A., Carterni G., Cavanna L., Cazzaniga M., Cognetti F., Contu A., Cruciani G., Donadio M., Falcone A., Farci D., Forcignano R. C., Frassoldati A., Gaion F., Gamucci T., Giotta F., Livi L., Lorusso V., Maiello E., Marchetti P., Mariani G., Mion M., Moscetti L., Musolino A., Pazzola A., Pedrazzoli P., Pigi A., de Placido S., Caremoli E. R., Santoro A., Tienghi A., Ahn J. -S., Lee K. S., Lee S. H., Seo J. H., Sohn J. -H., Cesas A., Juozaityte E., Cheah N. L. C., Chong F. L. T., Devi B. C. R., Phua V., Teoh D., Ching L. W., Yusof M., Corona J., Dominguez A., Mendoza R. L. G., Hernandez C. A., Ramiro A. J., Santos J. M., Espinosa P. M., Villarreal Garza C. M., Errihani H., Bakker S., van den Berkmortel F., Blaisse R. J. B., Huinink D. T. B., van den Bosch J., Braun J. J., Dercksen M. W., Droogendijk H., Erdkamp F., Haringhuizen A., de Jongh F. E., Kok T. C., Los M., Madretsma S., Terwogt J. M. M., van der Padt A., van Rossum-Schornagel Q. C., Smilde T. J., de Valk B., van der Velden A., van Warmerdam L., van de Wouw A. J., North R., Kersten C., Mjaaland I., Wist E., Aziz Z., Masood N., Rashid K., Shah M., Alcedo J. C., Aleman D., Neciosup S., Reategui R., Valdiviezo N., Vera L., Fernando G., Roque F., Strebel H. M., Krzemieniecki K., Litwiniuk M., Mruk A., Pienkowski T., Sawrycki P., Slomian G., Tomczak P., Afonso N., Cardoso F., Damasceno M., Nave M., Badulescu F., Ciule L., Curescu S., Eniu A., Filip D., Grecea D., Jinga D. -C., Lungulescu D., Oprean C. M., Stanculeanu D. L., Turdean M., Dvornichenko V., Emelyanov S., Lichinitser M., Manikhas A., Sakaeva D., Shirinkin V., Stroyakovskiy D., Abulkhair O., Zekri J., Filipovic S., Kovcin V., Nedovic J., Pesic J., Vasovic S., Ng R., Bystricky B., Leskova J., Mardiak J., Misurova E., Wagnerova M., Takac I., Demetriou G. S., Dreosti L., Govender P., Jordaan J. P., Veersamy P., Romero J. L. A., Lopez N. B., Arias C. C., Chacon J., Aramburo A. F., Morales L. A. F., Garcia M., Estevez L. G., Garcia-Palomo Perez A., Garcia Saenz J. A., Garcia Sanchis L., Cubells L. G., Cortijo L. G., Santiago S. G., De Aranguiz B. H. F., Manas J. J. I., Gallego P. J., Cussac A. L., Ferrandiz C. L., Garrido M. L., Alvarez P. L., Vega J. M. L., Del Prado P. M., Janez N. M., Murillo S. M., Rosales A. M., Jaso L. M., Fernandez I. P., Martorell A. P., Carrion R. P., Simon S. P., Alcibar A. P., Lorenzo J. P., Garcia V. Q., Asensio T. R. Y. C., Maicas M. D. T., Villanueva Silva M. J., Killander F., Svensson J. H., Fehr M., Hauser N., Muller A., Pagani O., Passmann-Kegel H., Popescu R., Rabaglio M., Rauch D., Schlatter C., Zaman K., Chang T. -W., Huang C. -S., Wang H. -C., Yu J. -C., Bandidwattanawong C., Maneechavakajorn J., Seetalarom K., Dejthevaporn T. S., Somwangprasert A., Vongsaisuwon M., Akbulut H., Altundag K., Arican A., Bozcuk H., Eralp Y., Idris M., Isikdogan A., Senol C. H., Sevinc A., Uygun K., Yucel E., Yucel I., Yumuk F., Shparyk Y., Voitko N., Jaloudi M., Adams J., Agrawal R., Ahmed S., Alhasso A., Allerton R., Anwar S., Archer C., Ashford R., Barraclough L., Bertelli G., Bishop J., Branson T., Butt M., Chakrabarti A., Chakraborti P., Churn M., Crowley C., Davis R., Dhadda A., Eldeeb H., Fraser J., Hall J., Hickish T., Hogg M., Howe T., Joffe J., Kelleher M., Kelly S., Kendall A., Kristeleit H., Lumsden G., Macmillan C., MacPherson I., Malik Z., Mithal N., Neal A., Panwar U., Proctor A., Proctor S. J., Raj S., Rehman S., Sandri I., Scatchard K., Sherwin E., Sims E., Singer J., Smith S., Tahir S., Taylor W., Tsalic M., Wardley A., Waters S., Wheatley D., Wright K., Yuille F., Alonso I., Artagaveytia N., Rodriguez R., Arbona E., Garcia Y., Lion L., Marcano D., Van Thuan T., Gligorov, J, Ataseven, B, Verrill, M, de Laurentiis, M, Jung, K, Azim, H, Al-Sakaff, N, Lauer, S, Shing, M, Pivot, X, Koroveshi, D, Bouzid, K, Casalnuovo, M, Cascallar, D, Korbenfeld, E, Bastick, P, Beith, J, Colosimo, M, Friedlander, M, Ganju, V, Green, M, Patterson, K, Redfern, A, Richardson, G, Ceric, T, Gordana, K, Beato, C, Ferrari, M, Hegg, R, Helena, V, Ismael, G, Lessa, A, Mano, M, Morelle, A, Nogueira, J, Timcheva, K, Tomova, A, Tsakova, M, Zlatareva-Petrova, A, Asselah, J, Assi, H, Brezden-Masley, C, Chia, S, Freedman, O, Harb, M, Joy, A, Kulkarni, S, Prady, C, Gaete, A, Matamala, L, Torres, R, Yanez, E, Franco, S, Urrego, M, Gugic, D, Vrbanec, D, Melichar, B, Prausova, J, Vyzula, R, Pilarte, R, Leon, M, Munoz, R, Ramos, G, Azeem, H, Aziz, A, El Zawahry, H, Osegueda, F, Alexandre, J, Artignan, X, Barletta, H, Beguier, E, Berdah, J, Marty, C, Bollet, M, Bourgeois, H, Bressac, C, Burki, F, Campone, M, Coeffic, D, Cojocarasu, O, Dagada, C, Dalenc, F, Del Piano, F, Desauw, C, Desmoulins, I, Dohollou, N, Egreteau, J, Ferrero, J, Foa, C, Garidi, R, Gasnault, L, Guardiola, E, Hamizi, S, Jarcau, R, Jacquin, J, Jaubert, D, Jolimoy, G, Mineur, H, Largillier, R, Leduc, B, Martin, P, Melis, A, Monge, J, Moullet, I, Mousseau, M, Nguyen, S, Orfeuvre, H, Petit, T, Priou, F, Bach, I, Simon, H, Stefani, L, Uwer, L, Youssef, A, Aktas, B, von der Assen, A, Augustin, D, Balser, C, Bauer, L, Bechtner, C, Beyer, G, Brucker, C, Buckner, U, Busch, S, Christensen, B, Deryal, M, Farrokh, A, Faust, E, Friedrichs, K, Graf, H, Griesshammer, M, Grischke, E, Hanle, C, Heider, A, Henschen, S, Hesse, T, Jackisch, C, Kisro, J, Kohler, A, Kuemmel, S, Lampe, D, Lantzsch, T, Latos, K, Lex, B, Liedtke, C, Luedders, D, Maintz, C, Muller, V, Overkamp, F, Park-Simon, T, Paul, M, Prechtl, A, Ringsdorf, U, Runnebaum, I, Ruth, S, Salat, C, Scheffen, I, Schilling, J, Schmatloch, S, Schmidt, M, Schneeweiss, A, Schrader, I, Seipelt, G, Simon, E, Stefek, A, Stickeler, E, Thill, M, Tio, J, Tuczek, A, Warm, M, Weigel, M, Wischnik, A, Wojcinski, S, Ziegler-Lohr, K, Aravantinos, G, Ardavanis, A, Fountzilas, G, Gogas, H, Kakolyris, S, Mavroudis, D, Papadimitriou, C, Papandreou, C, Papazisis, K, Castro, H, Hernandez-Monroy, C, Ngan, R, Yeo, W, Bittner, N, Boer, K, Csejtei, A, Horvath, Z, Kocsis, J, Mangel, L, Mezei, K, Nagy, Z, Szanto, J, Atmakusuma, D, Fadjari, H, Kurnianda, D, Prayogo, N, Tanggo, E, Coate, L, Hennessy, B, Kelly, C, Martin, M, Nasim, S, O'Connor, M, Aieta, M, Allegrini, G, Amadori, D, Bidoli, P, Biti, G, Bordonaro, R, Bottini, A, Carterni, G, Cavanna, L, Cazzaniga, M, Cognetti, F, Contu, A, Cruciani, G, Donadio, M, Falcone, A, Farci, D, Forcignano, R, Frassoldati, A, Gaion, F, Gamucci, T, Giotta, F, Livi, L, Lorusso, V, Maiello, E, Marchetti, P, Mariani, G, Mion, M, Moscetti, L, Musolino, A, Pazzola, A, Pedrazzoli, P, Pigi, A, de Placido, S, Caremoli, E, Santoro, A, Tienghi, A, Ahn, J, Lee, K, Lee, S, Seo, J, Sohn, J, Cesas, A, Juozaityte, E, Cheah, N, Chong, F, Devi, B, Phua, V, Teoh, D, Ching, L, Yusof, M, Corona, J, Dominguez, A, Mendoza, R, Hernandez, C, Ramiro, A, Santos, J, Espinosa, P, Villarreal Garza, C, Errihani, H, Bakker, S, van den Berkmortel, F, Blaisse, R, Huinink, D, van den Bosch, J, Braun, J, Dercksen, M, Droogendijk, H, Erdkamp, F, Haringhuizen, A, de Jongh, F, Kok, T, Los, M, Madretsma, S, Terwogt, J, van der Padt, A, van Rossum-Schornagel, Q, Smilde, T, de Valk, B, van der Velden, A, van Warmerdam, L, van de Wouw, A, North, R, Kersten, C, Mjaaland, I, Wist, E, Aziz, Z, Masood, N, Rashid, K, Shah, M, Alcedo, J, Aleman, D, Neciosup, S, Reategui, R, Valdiviezo, N, Vera, L, Fernando, G, Roque, F, Strebel, H, Krzemieniecki, K, Litwiniuk, M, Mruk, A, Pienkowski, T, Sawrycki, P, Slomian, G, Tomczak, P, Afonso, N, Cardoso, F, Damasceno, M, Nave, M, Badulescu, F, Ciule, L, Curescu, S, Eniu, A, Filip, D, Grecea, D, Jinga, D, Lungulescu, D, Oprean, C, Stanculeanu, D, Turdean, M, Dvornichenko, V, Emelyanov, S, Lichinitser, M, Manikhas, A, Sakaeva, D, Shirinkin, V, Stroyakovskiy, D, Abulkhair, O, Zekri, J, Filipovic, S, Kovcin, V, Nedovic, J, Pesic, J, Vasovic, S, Ng, R, Bystricky, B, Leskova, J, Mardiak, J, Misurova, E, Wagnerova, M, Takac, I, Demetriou, G, Dreosti, L, Govender, P, Jordaan, J, Veersamy, P, Romero, J, Lopez, N, Arias, C, Chacon, J, Aramburo, A, Morales, L, Garcia, M, Estevez, L, Garcia-Palomo Perez, A, Garcia Saenz, J, Garcia Sanchis, L, Cubells, L, Cortijo, L, Santiago, S, De Aranguiz, B, Manas, J, Gallego, P, Cussac, A, Ferrandiz, C, Garrido, M, Alvarez, P, Vega, J, Del Prado, P, Janez, N, Murillo, S, Rosales, A, Jaso, L, Fernandez, I, Martorell, A, Carrion, R, Simon, S, Alcibar, A, Lorenzo, J, Garcia, V, Asensio, T, Maicas, M, Villanueva Silva, M, Killander, F, Svensson, J, Fehr, M, Hauser, N, Muller, A, Pagani, O, Passmann-Kegel, H, Popescu, R, Rabaglio, M, Rauch, D, Schlatter, C, Zaman, K, Chang, T, Huang, C, Wang, H, Yu, J, Bandidwattanawong, C, Maneechavakajorn, J, Seetalarom, K, Dejthevaporn, T, Somwangprasert, A, Vongsaisuwon, M, Akbulut, H, Altundag, K, Arican, A, Bozcuk, H, Eralp, Y, Idris, M, Isikdogan, A, Senol, C, Sevinc, A, Uygun, K, Yucel, E, Yucel, I, Yumuk, F, Shparyk, Y, Voitko, N, Jaloudi, M, Adams, J, Agrawal, R, Ahmed, S, Alhasso, A, Allerton, R, Anwar, S, Archer, C, Ashford, R, Barraclough, L, Bertelli, G, Bishop, J, Branson, T, Butt, M, Chakrabarti, A, Chakraborti, P, Churn, M, Crowley, C, Davis, R, Dhadda, A, Eldeeb, H, Fraser, J, Hall, J, Hickish, T, Hogg, M, Howe, T, Joffe, J, Kelleher, M, Kelly, S, Kendall, A, Kristeleit, H, Lumsden, G, Macmillan, C, Macpherson, I, Malik, Z, Mithal, N, Neal, A, Panwar, U, Proctor, A, Proctor, S, Raj, S, Rehman, S, Sandri, I, Scatchard, K, Sherwin, E, Sims, E, Singer, J, Smith, S, Tahir, S, Taylor, W, Tsalic, M, Wardley, A, Waters, S, Wheatley, D, Wright, K, Yuille, F, Alonso, I, Artagaveytia, N, Rodriguez, R, Arbona, E, Garcia, Y, Lion, L, Marcano, D, Van Thuan, T, Gligorov J., Ataseven B., Verrill M., de Laurentiis M., Jung K. H., Azim H. A., Al-Sakaff N., Lauer S., Shing M., Pivot X., Koroveshi D., Bouzid K., Casalnuovo M., Cascallar D., Korbenfeld E. P., Bastick P., Beith J., Colosimo M., Friedlander M., Ganju V., Green M., Patterson K., Redfern A., Richardson G., Ceric T., Gordana K., Beato C. A., Ferrari M., Hegg R., Helena V., Ismael G. F., Lessa A. E., Mano M., Morelle A., Nogueira J. A., Timcheva K., Tomova A., Tsakova M., Zlatareva-Petrova A., Asselah J., Assi H., Brezden-Masley C., Chia S., Freedman O., Harb M., Joy A. A., Kulkarni S., Prady C., Gaete A. A. A., Matamala L., Torres R., Yanez E., Franco S., Urrego M., Gugic D., Vrbanec D., Melichar B., Prausova J., Vyzula R., Pilarte R. G., Leon M. I., Munoz R., Ramos G., Azeem H. A., Aziz A. A., El Zawahry H., Osegueda F. R., Alexandre J., Artignan X., Barletta H., Beguier E., Berdah J. -F., Marty C. B., Bollet M., Bourgeois H., Bressac C., Burki F., Campone M., Coeffic D., Cojocarasu O. Z., Dagada C., Dalenc F., Del Piano F., Desauw C., Desmoulins I., Dohollou N., Egreteau J., Ferrero J. -M., Foa C., Garidi R., Gasnault L., Guardiola E., Hamizi S., Jarcau R., Jacquin J. -P., Jaubert D., Jolimoy G., Mineur H. L., Largillier R., Leduc B., Martin P., Melis A., Monge J., Moullet I., Mousseau M., Nguyen S., Orfeuvre H., Petit T., Priou F., Bach I. S., Simon H., Stefani L., Uwer L., Youssef A., Aktas B., von der Assen A., Augustin D., Balser C., Bauer L. -E., Bechtner C., Beyer G., Brucker C., Buckner U., Busch S., Christensen B., Deryal M., Farrokh A., Faust E., Friedrichs K., Graf H., Griesshammer M., Grischke E. -M., Hanle C., Heider A., Henschen S., Hesse T., Jackisch C., Kisro J., Kohler A., Kuemmel S., Lampe D., Lantzsch T., Latos K., Lex B., Liedtke C., Luedders D., Maintz C., Muller V., Overkamp F., Park-Simon T. -W., Paul M., Prechtl A., Ringsdorf U., Runnebaum I., Ruth S., Salat C., Scheffen I., Schilling J., Schmatloch S., Schmidt M., Schneeweiss A., Schrader I., Seipelt G., Simon E., Stefek A., Stickeler E., Thill M., Tio J., Tuczek A., Warm M., Weigel M., Wischnik A., Wojcinski S., Ziegler-Lohr K., Aravantinos G., Ardavanis A., Fountzilas G., Gogas H., Kakolyris S., Mavroudis D., Papadimitriou C., Papandreou C., Papazisis K., Castro H., Hernandez-Monroy C. E., Ngan R., Yeo W., Bittner N., Boer K., Csejtei A., Horvath Z., Kocsis J., Mangel L. C., Mezei K., Nagy Z., Szanto J., Atmakusuma D., Fadjari H., Kurnianda D., Prayogo N., Tanggo E. H., Coate L., Hennessy B., Kelly C., Martin M., Nasim S., O'Connor M., Aieta M., Allegrini G., Amadori D., Bidoli P., Biti G., Bordonaro R., Bottini A., Carterni G., Cavanna L., Cazzaniga M., Cognetti F., Contu A., Cruciani G., Donadio M., Falcone A., Farci D., Forcignano R. C., Frassoldati A., Gaion F., Gamucci T., Giotta F., Livi L., Lorusso V., Maiello E., Marchetti P., Mariani G., Mion M., Moscetti L., Musolino A., Pazzola A., Pedrazzoli P., Pigi A., de Placido S., Caremoli E. R., Santoro A., Tienghi A., Ahn J. -S., Lee K. S., Lee S. H., Seo J. H., Sohn J. -H., Cesas A., Juozaityte E., Cheah N. L. C., Chong F. L. T., Devi B. C. R., Phua V., Teoh D., Ching L. W., Yusof M., Corona J., Dominguez A., Mendoza R. L. G., Hernandez C. A., Ramiro A. J., Santos J. M., Espinosa P. M., Villarreal Garza C. M., Errihani H., Bakker S., van den Berkmortel F., Blaisse R. J. B., Huinink D. T. B., van den Bosch J., Braun J. J., Dercksen M. W., Droogendijk H., Erdkamp F., Haringhuizen A., de Jongh F. E., Kok T. C., Los M., Madretsma S., Terwogt J. M. M., van der Padt A., van Rossum-Schornagel Q. C., Smilde T. J., de Valk B., van der Velden A., van Warmerdam L., van de Wouw A. J., North R., Kersten C., Mjaaland I., Wist E., Aziz Z., Masood N., Rashid K., Shah M., Alcedo J. C., Aleman D., Neciosup S., Reategui R., Valdiviezo N., Vera L., Fernando G., Roque F., Strebel H. M., Krzemieniecki K., Litwiniuk M., Mruk A., Pienkowski T., Sawrycki P., Slomian G., Tomczak P., Afonso N., Cardoso F., Damasceno M., Nave M., Badulescu F., Ciule L., Curescu S., Eniu A., Filip D., Grecea D., Jinga D. -C., Lungulescu D., Oprean C. M., Stanculeanu D. L., Turdean M., Dvornichenko V., Emelyanov S., Lichinitser M., Manikhas A., Sakaeva D., Shirinkin V., Stroyakovskiy D., Abulkhair O., Zekri J., Filipovic S., Kovcin V., Nedovic J., Pesic J., Vasovic S., Ng R., Bystricky B., Leskova J., Mardiak J., Misurova E., Wagnerova M., Takac I., Demetriou G. S., Dreosti L., Govender P., Jordaan J. P., Veersamy P., Romero J. L. A., Lopez N. B., Arias C. C., Chacon J., Aramburo A. F., Morales L. A. F., Garcia M., Estevez L. G., Garcia-Palomo Perez A., Garcia Saenz J. A., Garcia Sanchis L., Cubells L. G., Cortijo L. G., Santiago S. G., De Aranguiz B. H. F., Manas J. J. I., Gallego P. J., Cussac A. L., Ferrandiz C. L., Garrido M. L., Alvarez P. L., Vega J. M. L., Del Prado P. M., Janez N. M., Murillo S. M., Rosales A. M., Jaso L. M., Fernandez I. P., Martorell A. P., Carrion R. P., Simon S. P., Alcibar A. P., Lorenzo J. P., Garcia V. Q., Asensio T. R. Y. C., Maicas M. D. T., Villanueva Silva M. J., Killander F., Svensson J. H., Fehr M., Hauser N., Muller A., Pagani O., Passmann-Kegel H., Popescu R., Rabaglio M., Rauch D., Schlatter C., Zaman K., Chang T. -W., Huang C. -S., Wang H. -C., Yu J. -C., Bandidwattanawong C., Maneechavakajorn J., Seetalarom K., Dejthevaporn T. S., Somwangprasert A., Vongsaisuwon M., Akbulut H., Altundag K., Arican A., Bozcuk H., Eralp Y., Idris M., Isikdogan A., Senol C. H., Sevinc A., Uygun K., Yucel E., Yucel I., Yumuk F., Shparyk Y., Voitko N., Jaloudi M., Adams J., Agrawal R., Ahmed S., Alhasso A., Allerton R., Anwar S., Archer C., Ashford R., Barraclough L., Bertelli G., Bishop J., Branson T., Butt M., Chakrabarti A., Chakraborti P., Churn M., Crowley C., Davis R., Dhadda A., Eldeeb H., Fraser J., Hall J., Hickish T., Hogg M., Howe T., Joffe J., Kelleher M., Kelly S., Kendall A., Kristeleit H., Lumsden G., Macmillan C., MacPherson I., Malik Z., Mithal N., Neal A., Panwar U., Proctor A., Proctor S. J., Raj S., Rehman S., Sandri I., Scatchard K., Sherwin E., Sims E., Singer J., Smith S., Tahir S., Taylor W., Tsalic M., Wardley A., Waters S., Wheatley D., Wright K., Yuille F., Alonso I., Artagaveytia N., Rodriguez R., Arbona E., Garcia Y., Lion L., Marcano D., and Van Thuan T.

Abstract

Aim To assess the safety and tolerability of adjuvant subcutaneous trastuzumab (Herceptin® SC, H SC), delivered from an H SC Vial via hand-held syringe (Cohort A) or single-use injection device (Cohort B), with or without chemotherapy, for human epidermal growth factor receptor 2 (HER2)-positive stage I to IIIC early breast cancer (EBC) in the phase III SafeHer study (NCT01566721). Methods Patients received 600 mg fixed-dose H SC every 3 weeks for 18 cycles. The chemotherapy partner was at the investigators' discretion (H SC monotherapy was limited to ≤10% of the population). Data from the first H SC dose until 28 days (plus a 5-day window) after the last dose are presented. Results are descriptive. Results In the overall population, 2282/2573 patients (88.7%) experienced adverse events (AEs). Of the above, 128 (5.0%) patients experienced AEs leading to study drug discontinuation; 596 (23.2%) experienced grade ≥ 3 AEs and 326 (12.7%) experienced serious AEs. Grade ≥ 3 cardiac disorders were reported in 24 patients (0.9%), including congestive heart failure in eight (0.3%). As expected, the AE rates varied according to the timing of chemotherapy in both cohorts, with higher rates in concurrent versus sequential chemotherapy subgroups. In the concurrent chemotherapy subgroup, AEs were more common during the actual period of concurrent chemotherapy compared with the period when patients did not receive concurrent chemotherapy. Conclusion SafeHer confirms the safety and tolerability of the H SC 600 mg fixed dose for 1 year (every 3 weeks for 18 cycles) as adjuvant therapy with concurrent or sequential chemotherapy for HER2-positive EBC. These primary analysis results are consistent with the known safety profile for intravenous H and H SC.

Published
2017

38. Relation entre allergènes de l’environnement intérieur, sensibilisation et symptômes de rhinite et asthme allergiques [= Relationships between indoor allergens, sensitization, and allergic asthma and rhinitis symptoms]

Author

Casset, A. (Anne) and Braun, J. (J-J)

Subjects
immunology, complications, immune system diseases, adverse effects, etiology, Sciences du Vivant [q-bio]/Médecine humaine et pathologie, respiratory tract diseases
Abstract

INTRODUCTION: There is a strong and consistent association between immediate hypersensitivity, asthma and exposure to allergens. However, the role that the inhaled allergen plays and the timing of events related to sensitization are still controversial. BACKGROUND: Information obtained by studies of the follow-up of cohorts underlines the fact that there is no continuum between specific IgE responses and the development of childhood asthma. Allergic rhinitis and asthma result from a complex and multifactorial interaction between genetic factors, exposure to allergens, and many biological or chemical co-factors. However, when the child is exposed to an allergen, sensitization to the allergen is a risk factor for childhood asthma and severity of the disease. CONCLUSIONS AND VIEWPOINTS: Despite numerous epidemiological studies, the association and links between atopy, allergens, environment, sensitization and allergic rhinitis and/or asthma remain difficult to evaluate and poorly understood. Complementary studies are also necessary for the standardization of therapeutic strategies. english abstract journal article review 2010 Oct 2010 09 20 imported

Published
2010

39. Résultats atypiques et faux négatifs de la scintigraphie au 67Ga et de la TEP-TDM au 18F-FDG chez une patiente avec sarcoïdose et cancer du sein bilattéral

Author

Keomany, J., Imperiale, A., Thiriat, S., Braun, J.-J., Constantinesco, A., Service de Biophysique et Médecine Nucléaire, CHU Strasbourg-Université Louis Pasteur - Strasbourg I-Hôpital de Hautepierre [Strasbourg], Service ORL, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, neurospin institut d'imagerie biomédicale, and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)

Subjects
[SPI.MECA.BIOM]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Biomechanics [physics.med-ph], [PHYS.MECA.BIOM]Physics [physics]/Mechanics [physics]/Biomechanics [physics.med-ph], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2009
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40. 18-FDG PET-CT in sarcoidisosis management : revue and report of 20 cases

Author

Braun, J.-J., Kessler, R., Constantinesco, André, Imperiale, A., Remond, Yves, Service ORL, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, service de pneumologie Lyautey, Service de pneumologie, CHU Strasbourg-Hopital Civil, Service de Biophysique et Médecine Nucléaire, and CHU Strasbourg-Université Louis Pasteur - Strasbourg I-Hôpital de Hautepierre [Strasbourg]

Subjects
[SPI.MECA.BIOM] Engineering Sciences [physics]/Mechanics [physics.med-ph]/Biomechanics [physics.med-ph], [PHYS.MECA.BIOM] Physics [physics]/Mechanics [physics]/Biomechanics [physics.med-ph], [SPI.MECA.BIOM]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Biomechanics [physics.med-ph], [PHYS.MECA.BIOM]Physics [physics]/Mechanics [physics]/Biomechanics [physics.med-ph], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2008

41. Buiten het ziekenhuis opgelopen pneumonie: verwekkers en beloop bij patiënten opgenomen in een algemeen ziekenhuis

Author

Braun, J. J., de Graaff, C. S., de Goey, J., Zwinderman, A. H., Petit, P. L., and Epidemiology and Data Science

Abstract

OBJECTIVE: To determine prognostic factors and the significance of (non-invasive) microbiological tests for the clinical course of patients admitted to one general hospital with community-acquired pneumonia (CAP). DESIGN: Prospective observational study. METHOD: Patients admitted to one location of a general hospital with symptoms of CAP during the period January 1998-December 1999 were included. Data from the anamnesis, physical examination and laboratory tests were recorded and samples were taken for diagnosis of the possible pathogens. Cultures were made of sputum and blood, serum and sputum were examined for infection with viral and atypical microorganisms, and the urine was screened for Streptococcus pneumoniae and Legionella antigens. RESULTS: Of the 157 patients studied, 28 (18%) died as a direct result of CAP. In a stepwise multivariate analysis, age > or = 65 years, increased serum-creatinine levels and hypercapnia were independent predictors of mortality. Streptococcus pneumoniae and Haemophilus influenzae were detected 53 and 19 times, respectively, and were the bacterial pathogens most frequently found. Among the nonbacterial pathogens, Mycoplasma pneumoniae was found 37 times and serologic tests for influenza A or B virus were positive in 34 cases. In 62 patients (39%), extensive microbiological tests revealed signs of a combined infection and in 20 patients (13%) no microorganism could be detected. An elevated serum-procalcitonin level was associated with bacterial infections. As a consequence of their retrospective nature, the results of the extensive serological tests did not contribute to reaching a diagnosis in daily clinical practice. In comparison with the literature, there was a markedly high number of subclinical or atypical infections with Legionella (8%) and Bordetella (18%) and a high incidence of viral and atypical microorganisms as the cause of CAP

Published
2004

43. Land degradation and ecosystem services

Author

Lal, R, Lorenz, K, Hüttl, R F, Schneider, B U, von Braun, J, Lal, R ( R ), Lorenz, K ( K ), Hüttl, R F ( R F ), Schneider, B U ( B U ), von Braun, J ( J ), Bai, Zhanguo, Dent, David, Wu, Yunjin, de Jong, Rogier; https://orcid.org/0000-0002-6919-0936, Lal, R, Lorenz, K, Hüttl, R F, Schneider, B U, von Braun, J, Lal, R ( R ), Lorenz, K ( K ), Hüttl, R F ( R F ), Schneider, B U ( B U ), von Braun, J ( J ), Bai, Zhanguo, Dent, David, Wu, Yunjin, and de Jong, Rogier; https://orcid.org/0000-0002-6919-0936

Abstract

Destructive land use is driving long-term losses of ecosystem function and productivity. Satellite measurements of Normalized Difference Vegetation Index (NDVI) since 1981 provide a global yardstick, revealing that a quarter of the land surface has been degrading over the last quarter of a century; every continent and biome is affected with Africa south of the equator, southeast (SE) Asia and south (S) China hardest hit. The loss of primary productivity is equivalent to more than a billion Mg C but the associated emissions from loss of biomass and soil organic carbon are much greater. Degradation is not confined to farmland (18 % of the degrading area is cropland; 47 % is classed as forest); neither is it strongly associated with drylands, population pressure or poverty. A case study using more detailed data for China explores the effects of soil resilience and the association between land degradation and land use. NDVI can only be a proxy measure of land degradation; assessment of ecosystem services is a further step removed. Remotely-­sensed data can be used along with climatic and topographic data as an input to models that predict the provision of these services but the processes, drivers and effects beyond NPP are unseen and more importantly, unmeasured. This is an issue for emerging markets in environmental services.

Published
2013

45. Mesoaxial polydactyly is a major feature in Bardet–Biedl syndrome patients with LZTFL1 (BBS17) mutations

Author

Schaefer, E., primary, Lauer, J., additional, Durand, M., additional, Pelletier, V., additional, Obringer, C., additional, Claussmann, A., additional, Braun, J.‐J., additional, Redin, C., additional, Mathis, C., additional, Muller, J., additional, Schmidt‐Mutter, C., additional, Flori, E., additional, Marion, V., additional, Stoetzel, C., additional, and Dollfus, H., additional

Published
2013
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46. Maintenance treatment with capecitabine and bevacizumab versus observation after induction treatment with chemotherapy and bevacizumab in metastatic colorectal cancer (mCRC): The phase III CAIRO3 study of the Dutch Colorectal Cancer Group (DCCG).

Author

Koopman, Miriam, primary, Simkens, Lieke HJ, additional, Ten Tije, Albert J., additional, Creemers, Geert-Jan, additional, Loosveld, Olaf JL, additional, de Jongh, Felix E., additional, Erdkamp, Frans, additional, Erjavec, Zoran, additional, van der Torren, Adelheid ME, additional, Van der Hoeven, Jacobus JM, additional, Nieboer, Peter, additional, Braun, J. J., additional, Jansen, Rob L., additional, Haasjes, Janny G., additional, Cats, Annemieke, additional, Wals, Jacob J., additional, Mol, Linda, additional, Dalesio, Otilia, additional, van Tinteren, Harm, additional, and Punt, Cornelis J. A., additional

Published
2013
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