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1. Performance of the National OCS Program (NOP) in US Heart and Lung Transplants

Author

Hassanein, W., primary, Zafar, F., additional, Hassanein, A., additional, Al Salihi, M., additional, Reddy, S., additional, Dang, N., additional, Ihnken, K., additional, Kaw, A., additional, LaFrancesca, S., additional, Omara, M., additional, Tsonis, L., additional, Huang, Y., additional, Lezberg, P., additional, Jothidasan, A., additional, Damme, L., additional, Zhou, X., additional, Gensini, F., additional, Brann, S., additional, and Khayal, T., additional

Published
2024
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2. (622) First Report on the Performance of the National OCS Program (NOP) in U.S. Heart and Lung Transplants

Author

Hassanein, W., primary, Kane, L., additional, Lezberg, P., additional, Hassanein, A., additional, Dang, N., additional, LaFrancesca, S., additional, Kaw, A., additional, Brann, S., additional, Omara, M., additional, Reddy, S., additional, Ihnken, K., additional, Salihi, M. Al, additional, Zafar, F., additional, and Khayal, T., additional

Published
2023
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4. Trans-continental analysis of over, 2000 Inflammatory Bowel Disease patients implicates geography, disease type, and exposure to immunosuppression as drivers of SARS-CoV-2 seroprevalence : data from the ICARUS-IBD Consortium

Author

Wong, S. Y., Helmus, D., Marlow, L., Pazos, V. Martinez, Brann, S., Wellens, J., Kedia, S., Mak, J. W. Y., Bergemalm, Daniel, Argollo, M., Zaltman, C., Steinwurz, F., Rubin, D., Allez, M., Halfvarson, J., Abreu, M. T., Lindsay, J., Dutta, U., Silverberg, M. S., Ng, S. C., Ahuja, V., Watanabe, K., Vermeire, S., Colombel, J. F., Satsangi, J., Wong, S. Y., Helmus, D., Marlow, L., Pazos, V. Martinez, Brann, S., Wellens, J., Kedia, S., Mak, J. W. Y., Bergemalm, Daniel, Argollo, M., Zaltman, C., Steinwurz, F., Rubin, D., Allez, M., Halfvarson, J., Abreu, M. T., Lindsay, J., Dutta, U., Silverberg, M. S., Ng, S. C., Ahuja, V., Watanabe, K., Vermeire, S., Colombel, J. F., and Satsangi, J.

Published
2022
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7. DOP20 Functional viral neutralisation responses after SARS-CoV-2 infection in Inflammatory Bowel Disease patients receiving infusion therapies: Report from the ICARUS-IBD Consortium

Author

Wellens, J, primary, Edmans, M, additional, Obolski, U, additional, Marlow, L, additional, Brann, S, additional, Dunachie, S, additional, Eyre, D, additional, Helmus, D, additional, Barnes, E, additional, Colombel, J F, additional, Wong, S Y, additional, Klenerman, P, additional, Lindsay, J O, additional, Thompson, C P, additional, and Satsangi, J, additional

Published
2022
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8. P342 Trans-continental analysis of over, 2000 Inflammatory Bowel Disease patients implicates geography, disease type, and exposure to immunosuppression as drivers of SARS-CoV-2 seroprevalence: data from the ICARUS-IBD Consortium

Author

Wong, S Y, primary, Helmus, D, additional, Marlow, L, additional, Martinez Pazos, V, additional, Brann, S, additional, Wellens, J, additional, Kedia, S, additional, Mak, J W Y, additional, Bergemalm, D, additional, Argollo, M, additional, Zaltman, C, additional, Steinwurz, F, additional, Rubin, D, additional, Allez, M, additional, Halfvarson, J, additional, Abreu, M T, additional, Lindsay, J, additional, Dutta, U, additional, Silverberg, M S, additional, Ng, S C, additional, Ahuja, V, additional, Watanabe, K, additional, Vermeire, S, additional, Colombel, J F, additional, and Satsangi, J, additional

Published
2022
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25. Cohort profile: The Triple B Pregnancy Cohort Study: A longitudinal study of the relationship between alcohol, tobacco and other substance use during pregnancy and the health and well-being of Australian children and families

Author

Hutchinson, D., Wilson, J., Allsop, Steve, Elliott, E., Najman, J., Burns, L., Bartu, A., Jacobs, S., Honan, I., McCormack, C., Rossen, L., Fiedler, H., Stone, C., Khor, S., Ryan, J., Youssef, G., Olsson, C., Mattick, R., Cassar, J., Popescu, A., Campbell, G., Taylor, L., Gomez, M., Black, E., Braunstein, D., Dewberry, L., Kelly, E., Aiken, A., Brann, S., Clews, S., Dawe, S., Gordon, A., Haber, P., Hamilton, D., Lewis, A., McBride, Nyanda, Moore, E., Mutch, R., Oei, J., Patton, G., Rapee, R., Slade, T., Shanahan, M., Stephens, C., Teague, S., Ward, M., Hutchinson, D., Wilson, J., Allsop, Steve, Elliott, E., Najman, J., Burns, L., Bartu, A., Jacobs, S., Honan, I., McCormack, C., Rossen, L., Fiedler, H., Stone, C., Khor, S., Ryan, J., Youssef, G., Olsson, C., Mattick, R., Cassar, J., Popescu, A., Campbell, G., Taylor, L., Gomez, M., Black, E., Braunstein, D., Dewberry, L., Kelly, E., Aiken, A., Brann, S., Clews, S., Dawe, S., Gordon, A., Haber, P., Hamilton, D., Lewis, A., McBride, Nyanda, Moore, E., Mutch, R., Oei, J., Patton, G., Rapee, R., Slade, T., Shanahan, M., Stephens, C., Teague, S., and Ward, M.

Published
2018

33. The relationship of maternal gestational drug and alcohol intake, psychosocial functioning and lifetime mental disorder with anxiety and stress during pregnancy

Author

Brann, S, Hutchinson, Delyse, Wilson, J, Bucello, C, Honan, I, Gomez, M, Mattick, R, Allsop, S, Najman, J, Elliott, E, Burns, L, Jacobs, S, Olsson, C, Bartu, A, Brann, S, Hutchinson, Delyse, Wilson, J, Bucello, C, Honan, I, Gomez, M, Mattick, R, Allsop, S, Najman, J, Elliott, E, Burns, L, Jacobs, S, Olsson, C, and Bartu, A

Published
2012

34. The Triple B Study: pilot data on the association between drug and alcohol use in pregnancy and child development at one and three years of age

Author

Bucello, C, Fielder, H, Hutchinson, Delyse, Wilson, J, Honan, I, Brann, S, Mattick, R, Allsop, S, Sanson, A, Elliott, E, Burns, L, Jacobs, S, Olsson, C, Shand, F, McBride, N, Bucello, C, Fielder, H, Hutchinson, Delyse, Wilson, J, Honan, I, Brann, S, Mattick, R, Allsop, S, Sanson, A, Elliott, E, Burns, L, Jacobs, S, Olsson, C, Shand, F, and McBride, N

Published
2012

36. The relationship of maternal gestational drug and alcohol intake, psychosocial functioning and lifetime mental disorder with anxiety and stress during pregnancy

Author

Unknown, Brann, S., Hutchinson, D., Wilson, J., Bucello, C., Honan, I., Gomez, M., Mattick, R., Allsop, Steve, Najman, J., Elliott, E., Burns, L., Jacobs, S., Olsson, C., Bartu, Anne, Unknown, Brann, S., Hutchinson, D., Wilson, J., Bucello, C., Honan, I., Gomez, M., Mattick, R., Allsop, Steve, Najman, J., Elliott, E., Burns, L., Jacobs, S., Olsson, C., and Bartu, Anne

Published
2012

37. The Triple B Study: The relationship between pregnancy planning, parental substance use and maternal foetal attachment

Author

Unknown, Honan, I., Hutchinson, D., Wilson, J., Brann, S., Bucello, C., Gomez, M., Mattick, R., Allsop, Steve, Najman, J., Elliott, E., Burns, L., Jacobs, S., Olsson, C., Bartu, Anne, Unknown, Honan, I., Hutchinson, D., Wilson, J., Brann, S., Bucello, C., Gomez, M., Mattick, R., Allsop, Steve, Najman, J., Elliott, E., Burns, L., Jacobs, S., Olsson, C., and Bartu, Anne

Published
2012

41. Einfluβ einer Autobahn auf die Gehalte an IES, Chlorophyll, RNS und Protein bei Betula pendula und Cornus sanguinea.

Author

Brann, S., Oertli, J. J., and Flückiger, W.

Subjects
*EXPRESS highways, *INDOLEACETIC acid, *CHLOROPHYLL, *RNA, *PLANT clones, *EUROPEAN white birch
Abstract

The article discusses the effect of a motorway on the contents of Indole Acetic Acid (IAA), chlorophyll, Ribo Nucleic acid (RNA) and protein of young potted clones of Betula pendula and Cornus sanguinea. When these clones were exposed in the dividing strip of a motorway, contents of chlorophyll, RNA and protein decreased more rapidly during the growing period than those of control plants. The content of IAA in autumn was also lower. The article states that these results are interpreted as an earlier senescence of the plants at the motorway.

Published
1980
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42. Notizen

Author

Chronicle, Jewish and Brann, S.

Published
1857

43. Surgical management of a gigantic circumflex coronary artery aneurysm with fistulous connection to the coronary sinus.

Author

Chamberlain, M H, Henry, R, Brann, S, and Angelini, G D

Abstract

We report the successful management of a gigantic circumflex coronary artery aneurysm with fistulisation into the coronary sinus. Transoesophageal echocardiography allowed continuous visualisation of ventricular wall motion during dissection and closure of the aneurysm whilst operating on cardiopulmonary bypass on the beating heart.

Published
2001
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45. DOP20 Functional viral neutralisation responses after SARS-CoV-2 infection in Inflammatory Bowel Disease patients receiving infusion therapies: Report from the ICARUS-IBD Consortium

Author

Wellens J, Edmans M, Obolski U, Marlow L, Brann S, Dunachie S, David Eyre, Helmus D, Barnes E, Colombel J, Wong S, Klenerman P, Lindsay J, Thompson C, and Satsangi J

Subjects
Gastroenterology, General Medicine
Abstract

Background Recent data have highlighted adverse clinical outcomes in IBD patients treated with infliximab/thiopurines (IFX/THIO) upon infection with SARS-CoV-2, as well as attenuated serological responses after infection and vaccination in patients treated with IFX. To provide mechanistic insight, we explored the serological and functional anti-viral response after infection in IBD patients treated with VDZ, IFX or IFX/THIO compared to healthy controls to guide clinical decision-making regarding treatment and vaccination strategies. Methods Serum from 640 IBD patients attending routine infusions in Oxford and London in May to December 2020 was screened for anti-SARS-CoV-2 antibody responses by the Abbott assay. Serum from seropositive patients was compared to seropositive health care workers (Table 1). Antibody reactivity to the SARS-CoV-2 wild type strain receptor-binding domain (RBD), full-length spike, and nucleocapsid was assayed by IgG/IgA ELISA over time as well as by IgG high-throughput MSD V-PLEX ELISA at the time of seropositivity. A pseudotyped SARS-CoV-2 virus microneutralization assay was used to detect neutralising antibodies to the wild type, and an ELISA-based inhibition assay to compare differential inhibition of the wild type vs. delta variant SARS-CoV-2 RBD-ACE2 interaction. Results All IBD patients showed significantly reduced IgG antibody responses compared to healthy controls for all SARS-CoV-2 antigens, using MSD V-PLEX ELISA (Figure 1). The greatest reduction in IgG response by ELISA was observed in individuals treated with IFX/THIO (p=0.00019), whereas IgG response over time declined significantly faster in the IFX treated group (p=0.019). IgA responses were significantly reduced in the IFX/THIO group compared to healthy controls (p=0.009), but not in the IFX or VDZ monotherapy group. The rate of decline in these monotherapy groups was also not significantly different to healthy controls. Functional SARS-CoV-2 neutralisation was significantly lower in all IBD patients compared to healthy controls, with the greatest reduction in patients receiving IFX/THIO (Figure 2A; p=0.00000091). The delta variant inhibition capacity was significantly reduced in 68.1% of IBD patients (30/44, Figure 2B; p=0.0005). Conclusion IFX/THIO is associated with significantly lower IgA and IgG responses, and with impaired functional SARS-CoV-2 neutralising antibody capacity, compared to healthy individuals. Whilst IgG and neutralisation responses are reduced in each group of IBD patients, these findings were most pronounced in the combination treatment group. As neutralising antibody responses are associated with protection, this observation may impact on decision-making regarding treatment and vaccination/antiviral strategies.

46. Cohort profile: The Triple B Pregnancy Cohort Study: A longitudinal study of the relationship between alcohol, tobacco and other substance use during pregnancy and the health and well-being of Australian children and families

Author

Hutchinson, D., Wilson, J., Allsop, S., Elliott, E., Najman, J., Burns, L., Bartu, A., Jacobs, S., Honan, I., Mccormack, C., Rossen, L., Fiedler, H., Stone, C., Sarah Khor, Ryan, J., Youssef, G. J., Olsson, C. A., Mattick, R. P., Cassar, J., Popescu, A., Campbell, G., Taylor, L., Gomez, M., Black, E., Braunstein, D., Dewberry, L., Kelly, E., Aiken, A., Brann, S., Clews, S., Dawe, S., Gordon, A., Haber, P., Hamilton, D., Lewis, A., Mcbride, N., Moore, E., Mutch, R., Oei, J., Patton, G., Rapee, R., Slade, T., Shanahan, M., Stephens, C., Teague, S., and Ward, M.

47. Let's talk about how you should teach slavery.

Author

BRANN, S. KHALILAH

Subjects
*SLAVERY, *AFRICANS, *EDUCATION
Abstract

The article examines the need to teach slavery in New York City schools in a way which shows Africans as descendants of humans and not of slaves.

Published
2018

50. First Report on the Performance of the National OCS Program (NOP) in U.S. Heart and Lung Transplants.

Author

Hassanein, W., Kane, L., Lezberg, P., Hassanein, A., Dang, N., LaFrancesca, S., Kaw, A., Brann, S., Omara, M., Reddy, S., Ihnken, K., Salihi, M. Al, Zafar, F., and Khayal, T.

Subjects
*HEART transplantation, *LUNG transplantation, *HOMOGRAFTS, *TRANSPLANTATION of organs, tissues, etc., *CLINICAL medicine, *LUNG volume
Abstract

NOP utilizes a national network of dedicated cardiothoracic surgical procurement and Organ Care System (OCS) ex-vivo perfusion clinical expertise. The NOP was established to: maximize the utilization of donor hearts and lungs for transplantation; overcome the logistical and infrastructural burden of distant donor organ procurement and national allocation; standardize the clinical quality of care for ex-vivo perfusion and assessment of cardiothoracic allografts by minimizing learning curves; and to establish a better work-life balance for the valuable surgical and clinical transplant staff at transplant programs. We established sixteen NOP launching points across the continental U.S. to provide broad geographical coverage and facilitate national procurement of cardiothoracic organs (Figure 1). Each launch point is equipped with OCS heart and lung systems, cardiothoracic surgical procurement, and OCS perfusion expertise. The entire NOP program is supported by a 24X7 national hotline and coordinators team to provide timely response to the transplant programs' demand for NOP donor procurements. From January to October 2022 there were 321 heart and lung transplants from DBD and DCD donors performed on OCS technology across 35 U.S. heart and lung transplant programs. The percent utilization of NOP in these cases is shown in Figure 2. In its first year of operation, the NOP has been successfully integrated in the process of cardiothoracic organ transplants across the US and is growing. Importantly, there is growing confidence in distant procurement of hearts and lung from DBD and DCD donors by leveraging the NOP launch points. The continued adoption of NOP by transplant programs could potentially lead to a significant increase in heart and lung transplant volume in the U.S. [ABSTRACT FROM AUTHOR]

Published
2023
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