429 results on '"Brain, Body and Cognition"'
Search Results
2. Vertiges& troubles cognitifs: Le prix cérébral à payer pour garder l’équilibre
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Vrije Universiteit Brussel - Brain Body and Cognition Research Group, Department of Psychology and Educational Sciences, Lacroix, Emilie, Vrije Universiteit Brussel - Brain Body and Cognition Research Group, Department of Psychology and Educational Sciences, and Lacroix, Emilie
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- 2021
3. A State-of-the-Art Review on the Use of Modafinil as A Performance-enhancing Drug in the Context of Military Operationality
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VUB - Brain, Body and Cognition, Department of Psychology, Van Puyvelde Martine, Jeroen Van Cutsem, Lacroix, Emilie, Nathalie Pattyn, VUB - Brain, Body and Cognition, Department of Psychology, Van Puyvelde Martine, Jeroen Van Cutsem, Lacroix, Emilie, and Nathalie Pattyn
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Introduction: Modafinil is an eugeroic drug that has been examined to maintain or recover wakefulness, alertness, and cognitive performance when sleep deprived. In a nonmilitary context, the use of modafinil as a nootropic or smart drug, i.e., to improve cognitive performance without being sleep deprived, increases. Although cognitive performance is receiving more explicit attention in a military context, research into the impact of modafinil as a smart drug in function of operationality is lacking. Therefore, the current review aimed at presenting a current state-of-the-art and research agenda on modafinil as a smart drug. Beside the question whether modafinil has an effect or not on cognitive performance, we examined four research questions based on the knowledge on modafinil in sleep-deprived subjects: (1) Is there a difference between the effect of modafinil as a smart drug when administered in repeated doses versus one single dose?; (2) Is the effect of modafinil as a smart drug dose-dependent?; (3) Are there individual-related and/or task-related impact factors?; and (4) What are the reported mental and/or somatic side effects of modafinil as a smart drug? Method: We conducted a systematic search of the literature in the databases PubMed, Web of Science, and Scopus, using the search terms "Modafinil" and "Cognitive enhance*" in combination with specific terms related to the research questions. The inclusion criteria were studies on healthy human subjects with quantifiable cognitive outcome based on cognitive tasks. Results: We found no literature on the impact of a repeated intake of modafinil as a smart drug, although, in users, intake occurs on a regular basis. Moreover, although modafinil was initially said to comprise no risk for abuse, there are now indications that modafinil works on the same neurobiological mechanisms as other addictive stimulants. There is also no thorough research into a potential risk for overconfidence, whereas this risk was identif
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- 2021
4. Accelerated Repetitive Transcranial Magnetic Stimulation to Treat Major Depression: The Past, Present, and Future
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Chen, Leo, Klooster, Deborah C W, Tik, Martin, Thomas, Elizabeth H X, Downar, Jonathan, Fitzgerald, Paul B, Williams, Nolan R, Baeken, Chris, Clinical sciences, Brain, Body and Cognition, Neuroprotection & Neuromodulation, and Psychiatry
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Psychiatry and Mental health ,Treatment Outcome ,Depressive Disorder, Major/drug therapy ,Humans ,Depression/therapy ,Antidepressive Agents/therapeutic use ,Transcranial Magnetic Stimulation/adverse effects - Abstract
Repetitive transcranial magnetic stimulation (rTMS) is an effective and evidence-based therapy for treatment-resistant major depressive disorder. A conventional course of rTMS applies 20-30 daily sessions over 4-6 weeks. The schedule of rTMS delivery can be accelerated by applying multiple stimulation sessions per day, which reduces the duration of a treatment course with a predefined number of sessions. Accelerated rTMS reduces time demands, improves clinical efficiency, and potentially induces faster onset of antidepressant effects. However, considerable heterogeneity exists across study designs. Stimulation protocols vary in parameters such as the stimulation target, frequency, intensity, number of pulses applied per session or over a course of treatment, and duration of intersession intervals. In this article, clinician-researchers and neuroscientists who have extensive research experience in accelerated rTMS synthesize a consensus based on two decades of investigation and development, from early studies ("Past") to contemporaneous theta burst stimulation, a time-efficient form of rTMS gaining acceptance in clinical settings ("Present"). We propose descriptive nomenclature for accelerated rTMS, recommend avenues to optimize therapeutic and efficiency potential, and suggest using neuroimaging and electrophysiological biomarkers to individualize treatment protocols ("Future"). Overall, empirical studies show that accelerated rTMS protocols are well tolerated and not associated with serious adverse effects. Importantly, the antidepressant efficacy of accelerated rTMS appears comparable to conventional, once daily rTMS protocols. Whether accelerated rTMS induces antidepressant effects more quickly remains uncertain. On present evidence, treatment protocols incorporating high pulse dose and multiple treatments per day show promise and improved efficacy.
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- 2023
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5. Prefrontal transcranial direct current stimulation over the right prefrontal cortex reduces proactive and reactive control performance towards emotional material in healthy individuals
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Marie-Anne Vanderhasselt, Alvaro Sanchez-Lopez, Matias Pulopulos, Lais B. Razza, Stefanie De Smet, André Russowsky Brunoni, Chris Baeken, Rudi De Raedt, Jens Allaert, Clinical sciences, Brain, Body and Cognition, Neuroprotection & Neuromodulation, and Psychiatry
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Right prefrontal cortex ,Clinical Psychology ,Proactive and reactive cognitive control ,Psychiatry and Mental health ,Neuromodulation ,neuromodulation ,Medicine and Health Sciences ,Pupil dilation ,Social Sciences ,anticipation ,Anticipation - Abstract
The prefrontal cortex plays a crucial role in cognitive processes, both during anticipatory and reactive modes of cognitive control. Transcranial Direct Current Stimulation (tDCS) can modulate these cognitive resources. How-ever, there is a lack of research exploring the impact of tDCS on emotional material processing in the prefrontal cortex, particularly in regard to proactive and reactive modes of cognitive control. In this study, 35 healthy volun-teers underwent both real and sham tDCS applied to the right prefrontal cortex in a counterbalanced order, and then completed the Cued Emotion Control Task (CECT). Pupil dilation, a measure of cognitive resource allocation, and behavioral outcomes, such as reaction time and accuracy, were collected. The results indicate that, as com-pared to sham stimulation, active right-sided tDCS reduced performance and resource allocation in both proactive and reactive modes of cognitive control. These findings highlight the importance of further research on the effects of tDCS applied to the right prefrontal cortex on cognitive engagement, particularly for clinical trials utilizing the present electrode montage in combination with cognitive interventions.
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- 2023
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6. Measuring Personality Systems in Older Adults: Age-Neutrality of the Dutch BIS/BAS Questionnaire
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Sophie A Derksen, Xenia Brancart, Gina Rossi, Brussels University Consultation Center, Metajuridica, Psychology, Brain, Body and Cognition, Personality and Psychopathology, and Faculty of Psychology and Educational Sciences
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Psychiatry and Mental health ,Psychology Research and Behavior Management ,General Psychology - Abstract
Sophie A Derksen, Xenia Brancart, Gina Rossi Department of Psychology, Personality and Psychopathology Research Group (PEPS), Vrije Universiteit Brussel (VUB), Brussels, BelgiumCorrespondence: Sophie A Derksen, PE-PEPS, Vrije Universiteit Brussel (VUB), Pleinlaan 2, Brussels, 1050, Belgium, Email sophiederksen@outlook.comIntroduction: With a rapidly aging population, age-neutrality of psychological instruments is becoming ever more important for accurate assessment of older adults. This study aims to test the age-neutrality of the Dutch Behavioral Inhibition System/Behavioral Approach System (BIS/BAS) scales by means of Differential Item Functioning (DIF) and Differential Test Functioning (DTF) analyses.Methods: DIF and DTF analyses were conducted using an odds ratio approach. Potential DIF was examined for the two primary scales and three BAS subscales in 390 Dutch-speaking participants divided over three age groups.Results: Overall, the BIS-BAS scales lacked age-neutrality when comparing older adults to young adults: eight out of 20 items (ie, 40%) displayed DIF according to the adjusted Bonferroni corrected cut-offs, which exceeds the threshold of 25% for large DIF. Thus, for 40% of the test items, items were differently endorsed by young and older adults with the same position on the construct measured by the item. Therefore, the implications of the item-level DIF on the scale level were investigated across age groups. DTF analyses revealed large DTF for all BIS and BAS scales according to the adjusted Bonferroni corrected cut-offs.Discussion: DIF found in items on the BIS scale and BAS-Drive and BAS-Fun Seeking scale can probably be explained by a difference in degree of expression across age groups. A solution could be the development of age-specific norms. DIF on BAS-Reward Responsiveness subscale could be partly due to measuring a different construct across age groups. Rephrasing or replacing such items with DIF may increase age-neutrality of the BIS/BAS Scales.Keywords: older adults, BIS/BAS questionnaire, personality, assessment, differential item functioning
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- 2023
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7. Relationships Between DSM-5 Personality Disorders and Early Maladaptive Schemas from the Perspective of Dimensional and Categorical Comorbidity
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Bettina Steylaerts, Eva Dierckx, Chris Schotte, Faculty of Psychology and Educational Sciences, Society and Ageing Research Lab, Brussels University Consultation Center, Psychology, Brain, Body and Cognition, and Personality and Psychopathology
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Clinical Psychology ,Experimental and Cognitive Psychology - Abstract
Background Personality disorders (PDs) are highly prevalent in clinical populations, causing patients to suffer from significant everyday impairment. According to Young’s schema theory, early maladaptive schemas (EMSs) are the driving force behind PDs. Methods Within a large clinical sample of 2043 psychiatric patients, we measured personality pathology through the ADP-IV and EMSs through the YSQ-SF. We provide new perspectives into the existing research by controlling for personality pathology that is highly comorbid within the sample, using dimensional (PD traits) and categorical (PD diagnoses) paradigms. Associations between EMS and ADP-IV dimensional scales were examined through partial correlations, while controlling for all other highly intercorrelated PD trait scales. Within the categorical paradigm, we investigated relationships between EMS scales and ADP-IV PD diagnoses by means of logistic regression analyses, while controlling for the three PDs that were most prevalent and comorbid in the sample, namely borderline, avoidant and obsessive–compulsive PD. In all analyses, we added gender and general psychopathology—assessed through the SCL-90-R total score—as extra control variables. Results Substantial results, supported by both the correlation and regression analyses, strengthen previous evidence for relationships between paranoid PD and Mistrust/abuse EMS, schizotypal PD and Social isolation EMS, borderline PD and Abandonment EMS, narcissistic PD and Entitlement EMS, avoidant PD and Emotional inhibition EMS, dependent PD and Abandonment EMS and obsessive–compulsive PD and Unrelenting standards EMS. Moreover, we found substantial evidence for previously underreported relationships between avoidant PD and Social Isolation EMS, avoidant PD and Failure to achieve EMS, dependent PD and Dependence/incompetence EMS and dependent PD and Subjugation EMS. Conclusions By taking into account the clinical reality of dimensional and categorical comorbidity, this research allows for a more purified imageof the relations between PDs and EMSs, uncontaminated by the influence of comorbid PDs. Hence, our results provide relevant insights for the theoretical assumptions underlying PD-targeted cognitive-behavioral and schema therapy.
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- 2023
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8. The effects of left dorsolateral prefrontal transcranial direct current stimulation on episodic future thinking following acute psychosocial stress
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Linde De Wandel, Stefanie De Smet, Matias M. Pulopulos, Gilbert M. D. Lemmens, Vanesa Hidalgo, Alicia Salvador, Marie-Anne Vanderhasselt, Jens Pruessner, Chris Baeken, Brussels Heritage Lab, Clinical sciences, Brain, Body and Cognition, Neuroprotection & Neuromodulation, and Psychiatry
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Psychiatry and Mental health ,ddc:150 ,Arts and Humanities (miscellaneous) ,Montreal ImagingStress Task ,Transcranial direct current stimulation ,episodic futurethinking ,Montreal Imaging Stress Task ,cortisol ,episodic future thinking ,trait rumination ,Psychology(all) ,Transcranial direct currentstimulation ,General Psychology - Abstract
INTRODUCTION: Research on stress-related disorders and brain imaging suggests that (acute) stress might impact the capacity to mentally simulate specific episodic future events (EFT) through the effects of cortisol on brain regions supporting this cognitive function, such as the prefrontal cortices. This study aims to examine the mechanisms underlying this link, using transcranial Direct Current Stimulation (tDCS) over the left dorsolateral prefrontal cortex. METHODS: 60 healthy participants were subjected to the Montreal Imaging Stress Task (MIST), followed by either active or sham tDCS. After stimulation, the EFT task was administered. Salivary cortisol was measured throughout the protocol. RESULTS: Higher cortisol AUCi values were linked to less specific episodic future thoughts. Moreover, active tDCS enhanced EFT specificity irrespective of cortisol, especially in high trait ruminators. We did not observe an effect from active tDCS on cortisol AUCi, and equally there was no interaction effect between cortisol AUCi and stimulation condition predictive for EFT specificity. CONCLUSION: Although we did not find evidence for the effects of tDCS on the HPA-system, our data reveal a crucial link between two critical predictors of mental health for the first time, and provide a solution to help rehabilitate EFT deficits.Trial registration: Netherlands National Trial Register identifier: ntr004..
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- 2023
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9. Assessing Internalizing Symptoms and Their Relation with Levels of Impairment: Evidence-Based Cutoffs for Interpreting Inventory of Depression and Anxiety Symptoms (IDAS-II) Scores
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A. De la Rosa-Cáceres, O. M. Lozano, M. Sanchez-Garcia, F. Fernandez-Calderon, G. Rossi, C. Diaz-Batanero, Brussels University Consultation Center, Metajuridica, Psychology, Brain, Body and Cognition, and Personality and Psychopathology
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Impairment ,PROMs ,Clinical Psychology ,assessment ,cutoffs ,depression ,61 Psicología ,anxiety ,Emotional Disorders - Abstract
Tests and scales measuring psychological disorders should provide information about how scores relate to other constructs such as quality of life or functional impairment. Such information is necessary to allow their scores contribute to clinical decision-making. The current study analyzes the clinical utility of the Spanish version of the Inventory for Depression and Anxiety Symptoms (IDAS-II) to discriminate between different levels of functional impairment and identify the IDAS-II scales that contribute most to explaining impairment. The total sample (N=1390) consists of two subsamples: a community sample of the general population (n=1072) selected by random sampling; and a sample of patients (n=318) from public and private mental health services. The Spanish IDAS-II for measuring internalizing symptoms and WHODAS 2.0 for measuring impairment were administered to all participants. All scales show statistically significant higher scores in the patient sample, with Cohen's d effect sizes values greater than 0.30, except for well-being (d=0.19). The cutoff values and their confidence intervals do not overlap with the means of either the community or patient sample. AUC values for most of the scales are above .70, except for appetite gain, ordering, euphoria, cleaning, and well-being. Multiple linear regression model using IDAS-II scales explains 57.1% of the variance of the WHODAS 2.0 (F 12.1377=155.305; p, Funding for open access publishing: Universidad de Huelva/ CBUA. This work was supported by the grant “Reliable and clinical relevant change of Inventory of Depression and Anxiety Symptoms II – IDAS-II: a longitudinal clinical utility study (RELY-IDAS-II)”, project PID2020-116187RB-I00 on Proyectos I+D+i 2020 “Retos del Conocimiento” provided by Ministerio de Ciencia e Innovación (Spain); grant number FPU19/00144 provided by Ministerio de Universidades (Spain) and grant number PRX21/00319 provided by Ministerio de Ciencia e Innovación (Spain).
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- 2023
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10. Prevalence of Insomnia and Sleep Habits during the First and Second Wave of COVID-19 in Belgium
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Aurore Roland, Clara Colomb, Stéphane Noël, Arcady Putilov, Halszka Oginska, Bérénice Delwiche, Oumaima Benkirane, Maxime Windal, Nathalie Vanlaer, Giovanni Briganti, Judith Carrasquer-Ferrer, Behrouz Riahi, Charles Konreich, Daniel Neu, Johan Newell, Olivier Vermylen, Philippe Peigneux, Nathalie Pattyn, Johan Verbraecken, Ilse De Volder, Tim Vantilborgh, Joeri Hofmans, Martine Van Puyvelde, Olivier Mairesse, Faculty of Psychology and Educational Sciences, Psychology, Brussels University Consultation Center, Clinical sciences, Faculty of Medicine and Pharmacy, Physiotherapy, Human Physiology and Anatomy, Brain, Body and Cognition, Human Physiology and Sports Physiotherapy Research Group, and Work and Organizational Psychology
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Pandemic ,insomnia ,COVID-19 ,Psychology ,Sleep medicine, psychology ,sleep ,sleep habits ,pandemic ,General Psychology - Abstract
Belgium has one of the highest numbers of COVID-19 cases per 1 million inhabitants. The pandemic has led to significant societal changes with repercussions on sleep and on mental health. We aimed to investigate the effect of the first and the second wave of COVID-19 on the sleep of the Belgian populationWe launched two online questionnaires, one during the first lockdown (7240 respondents) and one during the second (3240 respondents), to test differences in self-reported clinical insomnia (as measured by the Insomnia Severity Index) and sleep habits during the two lockdowns in comparison with the pre-COVID period. The number of persons with clinical insomnia rose during the first lockdown (19.22%) and further during the second (28.91%) in comparison with pre-lockdown (7.04-7.66%). Bed and rise times were delayed and there was an increased time in bed and sleep onset latency. There was further a decrease in total sleep time and in sleep efficiency during both confinements. The prevalence of clinical insomnia quadrupled during the second wave in comparison with the pre-lockdown situation. Sleep habits were most altered in the younger population, indicating a greater risk for this group to develop a sleep-wake rhythm disorder.
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- 2023
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11. Dynamic causal modeling of cerebello-cerebral connectivity when sequencing trait-implying actions
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Min Pu, Qianying Ma, Naem Haihambo, Meijia Li, Chris Baeken, Kris Baetens, Natacha Deroost, Elien Heleven, Frank Van Overwalle, Brussels Heritage Lab, Psychology, Brain, Body and Cognition, Faculty of Psychology and Educational Sciences, Clinical sciences, Neuroprotection & Neuromodulation, Psychiatry, Brussels University Consultation Center, and Pharmaceutical and Pharmacological Sciences
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Psychiatry and Mental health ,Cellular and Molecular Neuroscience ,dynamic causal modeling (DCM) ,Neuroscience(all) ,Cognitive Neuroscience ,mentalizing ,Clinical psychology ,social action sequences ,Effective connectivity ,social violations ,Executive control ,the cerebellum - Abstract
Prior studies suggest that the cerebellum contributes to the prediction of action sequences as well as the detection of social violations. In this dynamic causal modeling study, we explored the effective connectivity of the cerebellum with the cerebrum in processing social action sequences. A first model aimed to explore functional cerebello-cerebral connectivity when learning trait/stereotype-implying action sequences. We found many significant bidirectional connectivities between mentalizing areas of the cerebellum and the cerebrum including the temporo-parietal junction (TPJ) and medial prefrontal cortex (mPFC). Within the cerebrum, we found significant connectivity between the right TPJ and the mPFC, and between the TPJ bilaterally. A second model aimed to investigate cerebello-cerebral connectivity when conflicting information arises. We found many significant closed loops between the cerebellum and cerebral mentalizing (e.g. dorsal mPFC) and executive control areas (e.g. medial and lateral prefrontal cortices). Additional closed loops were found within the cerebral mentalizing and executive networks. The current results confirm prior research on effective connectivity linking the cerebellum with mentalizing areas in the cerebrum for predicting social sequences, and extend it to cerebral executive areas for social violations. Overall, this study emphasizes the critical role of cerebello-cerebral connectivity in understanding social sequences.
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- 2022
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12. The effects of stimulating the cerebellum on social sequences
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Catoira, Beatriz, Overwalle, Frank Van, Schuerbeek, Peter Van, Raeymaekers, Hubert, Heleven, Elien, Baetens, Kris, Deroost, Natacha, Baeken, Chris, Clinical sciences, Brain, Body and Cognition, Faculty of Medicine and Pharmacy, Psychology, Brussels University Consultation Center, Supporting clinical sciences, Radiology, Medical Imaging, Pharmaceutical and Pharmacological Sciences, Neuroprotection & Neuromodulation, and Psychiatry
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Research on the involvement of the cerebellum in social behavior and its relationship with social mentalizing has just begun. Social mentalizing is the ability to attribute mental states such as desires, intentions, and beliefs to others. This ability involves the use of social action sequences which are believed to be stored in the cerebellum. In order to better understand the neurobiology of social mentalizing, we applied cerebellar transcranial direct current stimulation (tDCS) on 23 healthy participants in the MRI scanner, immediately followed by measuring their brain activity during a task that required to generate the correct sequence of social actions involving false (i.e., outdated) and true beliefs, social routines and non-social (control) events. The results revealed that stimulation decreased task performance along with decreased brain activation in mentalizing areas, including the temporoparietal junction and the precuneus. This decrease was strongest for true belief sequences compared to the other sequences. These findings support the functional impact of the cerebellum on the mentalizing network and belief mentalizing, contributing to the understanding of the role of the cerebellum in social sequences.
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- 2023
13. No place in France for repetitive transcranial magnetic stimulation in the therapeutic armamentarium of treatment-resistant depression?
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Jean-Marie Batail, Raphaël Gaillard, Emmanuel Haffen, Emmanuel Poulet, Anne Sauvaget, David Szekely, Jérôme Brunelin, Samuel Bulteau, Maxime Bubrovszky, Julien Smadja, Alexis Bourla, Noomane Bouaziz, Dominique Januel, Maud Rotharmel, Martijn Arns, Jonathan Downar, Paul B. Fitzgerald, André R. Brunoni, Stefano Pallanti, Giordano D'Urso, Chris Baeken, Nolan R. Williams, Bruno Millet, Jean-Pascal Lefaucheur, Dominique Drapier, Centre d'Investigation Clinique [Rennes] (CIC), Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Pontchaillou [Rennes], Centre d'Investigation Clinique de Besançon (Inserm CIC 1431), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement français du sang [Bourgogne-Franche-Comté] (EFS BFC)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center (CRNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), MIP UR 4334 - T2 - Coordinations motrices (MIP T2), Motricité, interactions, performance UR 4334 / Movement - Interactions - Performance (MIP), Le Mans Université (UM)-Nantes Université - UFR des Sciences et Techniques des Activités Physiques et Sportives (Nantes Univ - UFR STAPS), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Le Mans Université (UM)-Nantes Université - UFR des Sciences et Techniques des Activités Physiques et Sportives (Nantes Univ - UFR STAPS), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), MethodS in Patients-centered outcomes and HEalth ResEarch (SPHERE), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Nantes Université - UFR des Sciences Pharmaceutiques et Biologiques (Nantes Univ - UFR Pharmacie), Institut du Cerveau = Paris Brain Institute (ICM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Excitabilité nerveuse et thérapeutique (ENT), Hôpital Henri Mondor-EA 4391, Service de Physiologie Explorations Fonctionnelles-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Centre Hospitalier Guillaume Régnier [Rennes], Hawaii Academy of Science, 3,4, U.S. Food and Drug Administration, Brussels Heritage Lab, Clinical sciences, Brain, Body and Cognition, Neuroprotection & Neuromodulation, and Psychiatry
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Psychiatry and Mental health ,General Neuroscience ,treatment-resistant depression ,Biophysics ,repetitive transcranial magnetic stimulation ,[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] ,Neurology (clinical) ,France - Published
- 2023
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14. To Do or Not to Do
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Naem Haihambo, Qianying Ma, Kris Baetens, Min Pu, Natacha Deroost, Chris Baeken, Frank van Overwalle, Psychology, Faculty of Psychology and Educational Sciences, Brain, Body and Cognition, Brussels University Consultation Center, Clinical sciences, Neuroprotection & Neuromodulation, and Psychiatry
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Behavioral Neuroscience ,Cognitive Neuroscience - Abstract
Humans read the minds of others to predict their actions and efficiently navigate social environments, a capacity called mentalizing. Accumulating evidence suggests that the cerebellum, especially Crus 1 and 2, and lobule IX are involved in identifying the sequence of others’ actions. In the current study, we investigated the neural correlates that underly predicting others’ intentions and how this plays out in the sequence of their actions. We developed a novel intention prediction task, which required participants to put protagonists’ behaviors in the correct chronological order based on the protagonists’ honest or deceitful intentions (i.e., inducing true or false beliefs in others). We found robust activation of cerebellar lobule IX and key mentalizing areas in the neocortex when participants ordered protagonists’ intentional behaviors compared with not ordering behaviors or to ordering object scenarios. Unlike a previous task that involved prediction based on personality traits that recruited cerebellar Crus 1 and 2, and lobule IX (Haihambo et al., 2021), the present task recruited only the cerebellar lobule IX. These results suggest that cerebellar lobule IX may be generally involved in social action sequence prediction, and that different areas of the cerebellum are specialized for distinct mentalizing functions.
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- 2023
15. Personalizing Repetitive Transcranial Magnetic Stimulation Parameters for Depression Treatment Using Multimodal Neuroimaging
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P A J M Boon, Michael A. J. Ferguson, D C W Klooster, Chris Baeken, Brain, Body and Cognition, Clinical sciences, Neuroprotection & Neuromodulation, and Psychiatry
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CORTEX ,Computer science ,medicine.medical_treatment ,Cognitive Neuroscience ,RTMS ,Neuroimaging ,Electroencephalography ,NONINVASIVE BRAIN-STIMULATION ,Nuclear Medicine and imaging ,law.invention ,Magnetic resonance imaging ,Randomized controlled trial ,law ,SYNAPTIC PLASTICITY ,TARGETS ,medicine ,Medicine and Health Sciences ,Humans ,Radiology, Nuclear Medicine and imaging ,Biological Psychiatry ,Depressive Disorder, Major ,medicine.diagnostic_test ,IDENTIFICATION ,business.industry ,Depression ,CLINICAL-RESPONSE ,Brain ,FUNCTIONAL CONNECTIVITY ,medicine.disease ,Personalized medicine ,Transcranial magnetic stimulation ,Psychiatry and Mental health ,TMS ,EXCITABILITY ,Connectome ,Major depressive disorder ,Neurology (clinical) ,business ,Radiology ,Neuroscience ,Diffusion MRI - Abstract
Repetitive transcranial magnetic stimulation (rTMS) is a tool that can be used to administer treatment for neuropsychiatric disorders such as major depressive disorder, although the clinical efficacy is still rather modest. Overly general stimulation protocols that consider neither patient-specific depression symptomology nor individualized brain characteristics, such as anatomy or structural and functional connections, may be the cause of the high inter- and intraindividual variability in rTMS clinical responses. Multimodal neuroimaging can provide the necessary insights into individual brain characteristics and can therefore be used to personalize rTMS parameters. Optimal coil positioning should include a three-step process: 1) identify the optimal (indirect) target area based on the exact symptom pattern of the patient; 2) derive the cortical (direct) target location based on functional and/or structural connectomes derived from functional and diffusion magnetic resonance imaging data; and 3) determine the ideal coil position by computational modeling, such that the electric field distribution overlaps with the cortical target. These TMS-induced electric field simulations, derived from anatomical and diffusion magnetic resonance imaging data, can be further applied to compute optimal stimulation intensities. In addition to magnetic resonance imaging, electroencephalography can provide complementary information regarding the ongoing brain oscillations. This information can be used to determine the optimal timing and frequency of the stimuli. The heightened benefits of these personalized stimulation approaches are logically reasoned, but speculative. Randomized clinical trials will be required to compare clinical responses from standard rTMS protocols to personalized protocols. Ultimately, an optimized clinical response may result from precision protocols derived from combinations of personalized stimulation parameters.
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- 2022
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16. Unpacking psychological inequalities in organisations: Psychological capital reconsidered
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Edina Dóci, Lena Knappert, Sanne Nijs, Joeri Hofmans, Department of Human Resource Studies, Management and Organisation, Psychology, Faculty of Psychology and Educational Sciences, Work and Organizational Psychology, and Brain, Body and Cognition
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WORK ,RACE ,IMPACT ,Bourdieu ,POWER ,psychological capital ,EMPLOYEE PERFORMANCE ,critical work and organisational psychology ,JOB-PERFORMANCE ,critical theory ,Arts and Humanities (miscellaneous) ,inequalities ,Developmental and Educational Psychology ,STEREOTYPE CONTENT ,GENDER ,OCCUPATIONAL SEGREGATION ,Applied Psychology ,SOCIAL-CLASS - Abstract
In this paper, we argue that psychological capital is unequally distributed among people from different social classes, ethnic backgrounds and genders. Confronting the limitations of the current, individualistic perspective on psychological capital, we offer a re-conceptualisation of the construct from a critical, interdisciplinary perspective, placing it at the intersection of sociology and psychology. We discuss the various mechanisms through which social inequalities may cause differential access to psychological capital for members of low- and high-status social groups and show how this differential access to psychological capital results in and exacerbates social inequalities. By doing this, we postulate a recursive theory on psychological capital that both recognises the formative effect of socio-organisational structures on one's psychology and vice versa.
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- 2022
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17. Psychometric Properties of the Cognitive Emotion Regulation Questionnaire and Shortened Versions in Dutch Speaking Community-Dwelling Older Adults
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Gina Rossi, Xenia Brancart, Carmen Diaz-Batanero, Brussels University Consultation Center, Metajuridica, Psychology, Brain, Body and Cognition, Personality and Psychopathology, and Faculty of Psychology and Educational Sciences
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Most studies on the psychometric properties of the Cognitive Emotion Regulation Questionnaire (CERQ) were done in adolescents and adults. The scarce studies in older adults were mainly limited to associations of CERQ scales with internalising symptoms and wellbeing. Only one study explored the underlying factor structure in Spanish older adults and concluded that only a 27 item CERQ version showed adequate fit when tested with confirmatory factor analysis. The present study analyses the psychometric properties of all three versions of the CERQ in a sample of 451 community-dwelling older adults: the original 36 item CERQ, the short 18 item CERQ developed by the original authors and a Spanish 27 item CERQ version. Because gender differences among strategies used have been reported, the present study examined and provided first evidence for the gender invariance of the CERQ structure. Moreover, cognitive emotion regulation strategies correlated like hypothesized with clinical symptoms in general, and behavioural inhibition and activation systems and coping styles. The nomological net was highly similar for the original CERQ and shortened versions. The shortened versions of the CERQ consequently can be viable alternatives to the CERQ in settings where short assessment instruments are needed.
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- 2023
18. Longitudinal changes in global structural brain connectivity and cognitive performance in former hospitalized COVID‑19 survivors: an exploratory study
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B. Tassignon, A. Radwan, J. Blommaert, L. Stas, S. D. Allard, F. De Ridder, E. De Waele, L. C. Bulnes, N. Hoornaert, P. Lacor, E. Lathouwers, R. Mertens, M. Naeyaert, H. Raeymaekers, L. Seyler, A. M. Van Binst, L. Van Imschoot, L. Van Liedekerke, J. Van Schependom, P. Van Schuerbeek, M. Vandekerckhove, R. Meeusen, S. Sunaert, G. Nagels, J. De Mey, K. De Pauw, Human Physiology and Sports Physiotherapy Research Group, Physiotherapy, Human Physiology and Anatomy, Biostatistics and medical informatics, Public Health Sciences, Internal Medicine, Clinical sciences, Intensive Care, Brain, Body and Cognition, Psychology, Faculty of Psychology and Educational Sciences, Faculty of Medicine and Pharmacy, UZB Other, Microbiology and Infection Control, Faculty of Physical Education and Physical Therapy, Radiology, Supporting clinical sciences, Neurology, Laboratorium for Micro- and Photonelectronics, Artificial Intelligence supported Modelling in clinical Sciences, Electronics and Informatics, Neuroprotection & Neuromodulation, Medical Imaging, Rectorate, Experimental and Applied Psychology, Brubotics Rehabilitation Research Center, International Relations and Mobility, and Body Composition and Morphology
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Science & Technology ,SARS-CoV-2 ,General Neuroscience ,Neuroscience(all) ,Neurosciences ,SEGMENTATION ,RISK-TAKING ,Magnetic resonance imaging ,Recovery ,FMRI ,SIMILARITY ,Medicine and Health Sciences ,magnetic resonance imaging ,Neurosciences & Neurology ,NETWORK ,Life Sciences & Biomedicine ,DIFFUSION MRI - Abstract
Background Long-term sequelae of COVID-19 can result in reduced functionality of the central nervous system and substandard quality of life. Gaining insight into the recovery trajectory of admitted COVID-19 patients on their cognitive performance and global structural brain connectivity may allow a better understanding of the diseases' relevance. Objectives To assess whole-brain structural connectivity in former non-intensive-care unit (ICU)- and ICU-admitted COVID-19 survivors over 2 months following hospital discharge and correlate structural connectivity measures to cognitive performance. Methods Participants underwent Magnetic Resonance Imaging brain scans and a cognitive test battery after hospital discharge to evaluate structural connectivity and cognitive performance. Multilevel models were constructed for each graph measure and cognitive test, assessing the groups' influence, time since discharge, and interactions. Linear regression models estimated whether the graph measurements affected cognitive measures and whether they differed between ICU and non-ICU patients. Results Six former ICU and six non-ICU patients completed the study. Across the various graph measures, the characteristic path length decreased over time (β = 0.97, p = 0.006). We detected no group-level effects (β = 1.07, p = 0.442) nor interaction effects (β = 1.02, p = 0.220). Cognitive performance improved for both non-ICU and ICU COVID-19 survivors on four out of seven cognitive tests 2 months later (p Conclusion Adverse effects of COVID-19 on brain functioning and structure abate over time. These results should be supported by future research including larger sample sizes, matched control groups of healthy non-infected individuals, and more extended follow-up periods.
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- 2023
19. Exploring Recent Adverse and Positive Life Events: A Qualitative Study Among Lonely Older Adults
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Eva Dierckx, Liesbeth De Donder, Lise Switsers, Sarah Dury, Personality and Psychopathology, Educational Science, Psychology, Brain, Body and Cognition, Participation and Learning in Detention, Belgian Ageing Studies, and Brussels research center for Innovation in Learning and Diversity
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Gerontology ,Health (social science) ,Social network ,business.industry ,media_common.quotation_subject ,Meaningful use ,Breaking point ,Life events ,Living situation ,Loneliness ,Feeling ,medicine ,medicine.symptom ,business ,Psychology ,media_common ,Qualitative research - Abstract
This study investigates experiences of recent adverse and positive life events, and how these impact lonely older adults. Qualitative individual interviews were con- ducted with 53 community-dwelling, lonely older people aged 60 years and over. Analyses identified four key findings. First, the results pointed to a variety of recent life events in different domains (i.e., health, financial status, social network, living situation and meaningful use of time), which are experienced subjectively by par- ticipants. Second, life events occur at micro-biographical, meso-institutional, and macro-societal levels. Third, recent life events can signal gradual transitions or can constitute a breaking point. Fourth, while lonely older adults experience different recent adverse life events related to loss experiences, they also experience differ- ent positive recent life events, which might have the potential to increase their well- being or reduce feelings of loneliness. Finally, recent life events can have (cumula- tive)effects on their well-being. The conclusions highlight the need for an in-depth understanding of life events experienced in later life, given their potential role as balancing factors in the well-being of lonely older adults, as well as providing some implications for practice and policy.
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- 2023
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20. Neuroplasticity-Related Genes and Dopamine Receptors Associated with Regional Cortical Thickness Increase Following Electroconvulsive Therapy for Major Depressive Disorder
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Gong-Jun Ji, Jiao Li, Wei Liao, Yingru Wang, Lei Zhang, Tongjian Bai, Ting Zhang, Wen Xie, Kongliang He, Chuyan Zhu, Juergen Dukart, Chris Baeken, Yanghua Tian, Kai Wang, Clinical sciences, Brain, Body and Cognition, Neuroprotection & Neuromodulation, and Psychiatry
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Cellular and Molecular Neuroscience ,Psychiatry and Mental health ,Neurology ,major depressive disorder ,Neuroscience(all) ,Neuroscience (miscellaneous) ,Gene Expression ,Neurotransmitter ,cortical thickness ,electroconvulsive therapy - Abstract
Electroconvulsive therapy (ECT) is an effective neuromodulatory therapy for major depressive disorder (MDD). Treatment is associated with regional changes in brain structure and function, indicating activation of neuroplastic processes. To investigate the underlying neurobiological mechanism of macroscopic reorganization following ECT, we longitudinally (before and after ECT in two centers) collected magnetic resonance images for 96 MDD patients. Similar patterns of cortical thickness (CT) changes following ECT were observed in two centers. These CT changes were spatially colocalized with a weighted combination of genes enriched for neuroplasticity-related ontology terms and pathways (e.g., synaptic pruning) as well as with a higher density of D2/3 dopamine receptors. A multiple linear regression model indicated that the region-specific gene expression and receptor density patterns explained 40% of the variance in CT changes after ECT. In conclusion, these findings suggested that dopamine signaling and neuroplasticity-related genes are associated with the ECT-induced morphological reorganization.
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- 2023
21. The left ventrolateral prefrontal cortex as a more optimal target for accelerated rTMS treatment protocols for depression?
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Guo-Rong Wu, Chris Baeken, Brussels Heritage Lab, Clinical sciences, Brain, Body and Cognition, Neuroprotection & Neuromodulation, and Psychiatry
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covariance analysis ,Psychiatry and Mental health ,major depressive disorder ,General Neuroscience ,Accelerated HF-rTMS ,sgACC ,Biophysics ,Neurology (clinical) ,(18)FDG PET - Published
- 2023
22. Factor structure invariance of the Defense Style Questionnaire-60 in outpatients
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De Page, Louis, Rossi, Gina, Brussels University Consultation Center, Metajuridica, Psychology, Brain, Body and Cognition, and Personality and Psychopathology
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This study examined the content validity and consumer satisfaction of a newly developed forensic Measurement invariance across important subgroups such as gender and language has not yet been corroborated for Defense Style Questionnaire (DSQ). We examined the structure of the DSQ-60 (N= 509) using Exploratory Structural Equation Modelling with target rotation to the three factor-structure (Image distorting, Affect regulating and Adaptive style). We did find good fit to this 3-factor model for the data of the total group of outpatients. Next, we explored measurement invariance for both gender and language (French and Dutch). We did find configural invariance (i.e. pattern invariance) across gender and language. However, metric invariance (i.e. equal factor loadings) was not supported for gender and language. Moreover, the highest scale loadings were not always on the factor that would be expected based on three-factor solutions found earlier with different DSQ versions (i.e. an adaptive, image distorting style, and affect regulating style). We did find an adaptive and an image distorting factor. The third factor did not clearly represent the affect regulating style. We conclude that, although the widespread use of the DSQ, researchers must be careful in their use and interpretation of the DSQ-scales across important subgroups such as gender and language. Yet the DSQ is still a good screening measure for immature defenses and can give an indication of the presence of relatively more mature versus more immature defenses in an individual.
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- 2023
23. Immediate Effects of the Honda Walking Assist on Spatiotemporal Gait Characteristics in Older Adults
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Mahyar Firouzi, Emma De Keersmaec, Nina Lefeber, Stijn Roggeman, Erika Joos, Eric Kerckhofs, David Beckwée, Eva Swinnen, Brussels University Consultation Center, Rehabilitation Research, Physiotherapy, Human Physiology and Anatomy, Psychology, Brain, Body and Cognition, Faculty of Physical Education and Physical Therapy, Movement and Sport Sciences, Movement and Nutrition for Health and Performance, Physical Medicine and Rehabilitation, Clinical sciences, and Frailty in Ageing
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Rehabilitation ,Physical Therapy, Sports Therapy and Rehabilitation ,Geriatrics and Gerontology - Abstract
We compared changes in spatiotemporal gait parameters of 11 healthy older adults (mean age: 88.6 years) over 3 conditions of walking with the Honda Walking Assist (HWA), a hip-assistive exoskeleton. Differences in 14 gait parameters between (1) normal overground walking, (2) walking with a nonassisting HWA, and (3) optimally assisting HWA were analyzed using Friedman and Wilcoxon signed rank tests. Significant differences depending on type of assistance were found for 9 parameters. None persisted following Bonferroni corrections. Single-session individualized HWA assistance does not induce immediate changes in gait parameters. This does not contradict the potential of multiple training sessions with the HWA.
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- 2023
24. How Reliable are Personality Judgment by Political Experts? The Curious Case of Donald Trump
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Jeroen Joly, Joeri Hofmans, Work and Organizational Psychology, Psychology, and Brain, Body and Cognition
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General Medicine - Abstract
Recent studies have highlighted the importance of personality in electoral politics. With the rise of populist and atypical personalities across stable and established democracies, pundits, journalists and other political experts often rely on their assessments of politicians’ personalities to explain their behavior. Additionally, numerous citizens depend on their expertise and assessments to form their own opinion. Given that most political experts have never personally met these politicians, how reliable are their assessments of high-profile politicians’ personality? We address this question by analyzing inter-rater reliability of ratings of US President Trumps’ personality by seven Belgian political experts. Using the NEO-FFI, our analyses indicate low inter-rater agreement on most of the Big Five personality traits and the facets of Trumps’ personality. Therefore, the excessive use of analyses based on third party assessments and interpretations of politicians’ personality should be regarded with caution given their potential impact on the wider public.
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- 2023
25. Transcranial direct current stimulation versus intermittent theta-burst stimulation for the improvement of working memory performance
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Lais B. Razza, Matthias S. Luethi, Tamires Zanão, Stefanie De Smet, Carlos Buchpiguel, Geraldo Busatto, Juliana Pereira, Izio Klein, Mitchel Kappen, Marina Moreno, Chris Baeken, Marie-Anne Vanderhasselt, André R. Brunoni, Brain, Body and Cognition, Clinical sciences, Neuroprotection & Neuromodulation, and Psychiatry
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non-invasive brain stimulation ,prefrontal cortex ,Combined interventions ,DORSOLATERAL PREFRONTAL CORTEX ,Working memory ,Social Sciences ,DEPRESSION ,EFFICACY ,Prefrontal cortex ,MAGNETIC STIMULATION ,Synergistic effects ,TDCS ,Clinical Psychology ,Psychiatry and Mental health ,combined interventions ,Medicine and Health Sciences ,Non-invasive brain stimulation ,BRAIN ,Working Memory ,HEALTHY - Abstract
Non-invasive brain stimulation (NIBS) techniques have been increasingly used over the dorsolateral prefrontal cortex (DLPFC) to enhance working memory (WM) performance. Not-withstanding, NIBS protocols have shown either small or inconclusive cognitive effects on healthy and neuropsychiatric samples. Therefore, we assessed working memory performance and safety of transcranial direct current stimulation (tDCS), intermittent theta-burst stimulation (iTBS), and both therapies combined vs placebo over the neuronavigated left DLPFC of healthy participants. Twenty-four subjects were included to randomly undergo four sessions of NIBS, once a week: tDCS alone, iTBS alone, combined protocol and placebo. The 2-back task and an adverse effect scale were applied after each NIBS session. Results revealed a significantly faster response for iTBS (b=-21.49, p= 0.04), but not for tDCS and for the interaction tDCS vs. iTBS (b= 13.67, p= 0.26 and b= 40.5, p= 0.20, respectively). No changes were observed for accuracy and no serious adverse effects were found among protocols. Although tolerable, an absence of syner-gistic effects for the combined protocol was seen. Nonetheless, future trials accessing different outcomes for the combined protocols, as well as studies investigating iTBS over the left DLPFC for cognition and exploring sources of variability for tDCS are encouraged. (c) 2022 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC -ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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- 2023
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26. Stimulation of the dorsolateral prefrontal cortex modulates brain cue reactivity to reward (un)availability
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Damien Brevers, Chris Baeken, Stefanie De Smet, Beatriz Catoira, Sara De Witte, Qinghua He, Pierre Maurage, Laimi Schultze-Steinen, Guillaume Sescousse, Claudia Vila Verde, Claus Vögele, Joël Billieux, UCL - SSH/IPSY - Psychological Sciences Research Institute, Brussels Heritage Lab, Clinical sciences, Brain, Body and Cognition, Neuroprotection & Neuromodulation, Psychiatry, and Faculty of Medicine and Pharmacy
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Cognitive Neuroscience ,Neuroscience(all) ,Reward availability ,fMRI ,Prefrontal Cortex ,Brain ,Experimental and Cognitive Psychology ,behavioral disciplines and activities ,Transcranial Magnetic Stimulation ,Psychiatry and Mental health ,Neuropsychology and Physiological Psychology ,Dorsolateral Prefrontal Cortex ,nervous system ,Reward ,Cue reactivity ,rTMS ,Humans ,Dorsolateral prefrontal cortex ,Cues ,Ventral striatum ,cue reactivity ,psychological phenomena and processes - Abstract
Brain imaging studies have shown that stimulation of the left dorsolateral prefrontal cortex (dlPFC), which plays a pivotal role in high-order cognitive control processes, modulates brain reactivity to reward-related cues. Nevertheless, the impact of contextual factors such as reward availability (the reward that is depicted in the cue exposure task) on such modulation effect remains unclear. Here we tested whether a single session of high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) over the left dlPFC differently impacts brain reactivity to cues signalling either availability or unavailability of a sports betting opportunity. Employing a within-subject design (verum versus sham HF-rTMS) among thirty-two frequent sports bettors, we first observed that, as compared to the sham condition, verum HF-rTMS modulated brain reactivity to game cues prior to being made (un)available for betting, through simultaneous increases (posterior insula and caudate nucleus) and decreases (occipital pole) in brain activation. Second, verum HF-rTMS led to increased ventral striatal activity towards cues available for betting but did not modulate brain response to cues unavailable for betting. Third, exploratory functional connectivity analyses revealed increased negative coupling in the verum condition between the left dlPFC and the right and left superior frontal gyrus toward available and non-available betting cues, respectively. Taken together, these findings demonstrate that transient stimulation of the left dlPFC led to a general modulation in brain activity and functional connectivity in responses to cues, and that this effect is only partly dependent on cues signalling for reward (un)availability.
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- 2023
27. Combining transcranial direct current stimulation with group cognitive behavioral therapy developed to treat rumination : a clinical pilot study
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Paula Horczak, Chanyu Wang, Sara De Witte, Stefanie De Smet, Jonathan Remue, Rudi De Raedt, Marie-Anne Vanderhasselt, Guo-Rong Wu, Gilbert M. D. Lemmens, Chris Baeken, Brussels Heritage Lab, Neuroprotection & Neuromodulation, Clinical sciences, Brain, Body and Cognition, and Psychiatry
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NIBS ,major depressive disorder ,Neuroscience(all) ,Clinical Neurology ,Clinical psychology ,group cognitive behavioral therapy ,Social Sciences ,rumination ,psychotherapy ,Psychiatry and Mental health ,Generalized anxiety disorder ,Repetitive negative thinking ,Neurology ,Rumination ,Medicine and Health Sciences ,Transcranial direct current stimulation ,Neurology (clinical) ,transcranial direct current stimulation ,generalized anxiety disorder ,repetitive negative thinking - Abstract
BackgroundAs part of repetitive negative thinking (RNT), rumination is a maladaptive cognitive response style to stress or negative mood which can increase the risk of depression and may prohibit complete recovery. Cognitive behavioral therapy (CBT) and transcranial direct current stimulation (tDCS) both proved to be effective in decreasing rumination. However, the combined effects of tDCS and CBT interventions on rumination have not yet been explored. The first aim of this pilot study is to investigate whether the combination of tDCS and CBT has an accumulating positive effect on modulating state rumination. The second aim is to assess the feasibility and safety profile of the proposed combined approach.MethodSeventeen adults aged 32–60 years, suffering from RNT, were referred by their primary care professional to participate in an 8-week group intervention for RNT (“Drop It”) comprising 8 sessions of CBT. Before each CBT session, patients underwent one double-blinded prefrontal active (2 mA for 20 min) or sham tDCS (anode over F3, cathode over the right supraorbital region) combined with an internal cognitive attention task focused on individual RNT, i.e., online tDCS priming. During each session, the Brief State Rumination Inventory was used to assess state rumination.ResultsA mixed effects model analysis revealed no significant differences between the stimulation conditions, weekly sessions, or their interaction in terms of state rumination scores.ConclusionOverall, the combination of online tDCS priming followed by group CBT was found to be safe and feasible. On the other hand, no significant additional effects of this combined approach on state rumination were established. Although our pilot study may have been too small to find significant clinical effects, future larger RCT studies on combined tDCS-CBT treatment protocols may reevaluate the selection of internal cognitive attention tasks and more objective neurophysiological measurements, consider the optimal timing of the combination (concurrently or sequentially), or may add additional tDCS sessions when following CBT.
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- 2023
28. Contemporary Methodological Considerations for Key Issues in Research on Personality Disorder Development
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Joeri Hofmans, Jasmine Vergauwe, Barbara De Clercq, Psychology, Work and Organizational Psychology, and Brain, Body and Cognition
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Psychiatry and Mental health ,Clinical Psychology ,longitudinal ,analysis ,Medicine and Health Sciences ,Social Sciences ,personality disorders ,time ,methods - Abstract
In the present article, we aim to contribute to further progress in the field of personality disorder (PD) development by highlighting several recent methodological innovations related to (a) the measurement of personality pathology, (b) the modeling of typical features of personality pathology, and (c) the assessment of processes that characterize PD development. For each of those issues, we discuss key points of attention and methodological strategies, illustrated with recent publications in the PD research field as potential resources for future research.
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- 2023
29. The role of <scp>BIS</scp> / <scp>BAS</scp> in effective coping with psychological contract breach
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Yang Yang, Tim Vantilborgh, Psychology, Work and Organisational Psychology, Brussels University Consultation Center, Brain, Body and Cognition, and Work and Organizational Psychology
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Arts and Humanities (miscellaneous) ,Negotiating ,Adaptation, Psychological ,Humans ,Contracts ,General Medicine ,General Psychology ,Personality - Abstract
Psychological contract (PC) breach perceptions are formed when employees detect discrepancies between obligated and delivered inducements. PCB stresses and strains employees to varying degrees and has detrimental consequences for employees and the organisation. Employees activate various coping strategies to respond to the stress elicited by PCB, and effective coping helps enhance employees' well-being. In this study, we propose and test a moderated mediation model, where approach and avoidance coping strategies mediate the relationship between PCB and stress, and employees' goal-based personality (i.e., behavioural inhibition system-BIS and behavioural activation system-BAS) moderates the relationship between PCB and coping strategies. We further examine the effectiveness of the subdimensions of coping, as well as how BIS/BAS influences the choice of these subdimensions in a sample of Western employees. Our results suggest approach coping effectively reduces stress elicited by PCB, whereas avoidance coping increases stress. Moreover, employees with higher BAS are more likely to engage in approach coping, whereas those with higher BIS use avoidance coping. We advance the research on coping with PCB by showing a more nuanced understanding of the subdimensions of coping as well as exploring diverse personality models in moderating the choice of coping strategies.
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- 2021
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30. The baby and the bathwater: On the need for substantive–methodological synergy in organizational research
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Mo Wang, John P. Meyer, Thomas A. O'Neill, José A. Navarro, Evy Kuijpers, Zhonglin Wen, Eva Ceulemans, Jesse T. Vullinghs, Simon A. Houle, Vicente González-Romá, Katariina Salmela-Aro, Yvonne Van Rossenberg, István Tóth-Király, Herbert W. Marsh, Alexandre J. S. Morin, Jasmine Vergauwe, Sabine Sonnentag, Charles C. Driver, Nicolas Gillet, Léandre Alexis Chénard-Poirier, Elizabeth Olivier, Joeri Hofmans, Kit-Tai Hau, Ellen L. Hamaker, Theresa Leyens, Claude Fernet, Louis Tay, Matthew J. W. McLarnon, Bart Wille, Reinhard Pekrun, Robert J. Vallerand, Christian Vandenberghe, Tim Vantilborgh, Anne Mäkikangas, David Litalien, Joshua L. Howard, Omar Solinger, Kevin J. Grimm, Marylène Gagné, Rex B. Kline, Heiko Breitsohl, Leerstoel Hamaker, Methodology and statistics for the behavioural and social sciences, Work and Organizational Psychology, Psychology, Brain, Body and Cognition, Faculty of Psychology and Educational Sciences, Brussels University Consultation Center, Work and Organisational Psychology, Management and Organisation, Amsterdam Business Research Institute, Vrije Universiteit Brussel (VUB), Qualité de vie et Santé psychologique [Tours] (QualiPsy - E.E. 1901), Université de Tours, Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), and Université de Tours (UT)
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Social Psychology ,[SHS.PSY]Humanities and Social Sciences/Psychology ,050109 social psychology ,Latent variable ,Space (commercial competition) ,Field (computer science) ,Psicologia del treball ,0502 economics and business ,0501 psychology and cognitive sciences ,ComputingMilieux_MISCELLANEOUS ,Applied Psychology ,Reliability (statistics) ,Industrial psychology ,Descriptive statistics ,Syntax (programming languages) ,05 social sciences ,Methodology ,Metodologia ,Missing data ,Epistemology ,Psychology ,Institute for Management Research ,[STAT.ME]Statistics [stat]/Methodology [stat.ME] ,sustantive-methodological synergy ,Research methods ,050203 business & management ,Diversity (business) - Abstract
Murphy (2021) argues that the field of Industrial-Organizational (I/O) Psychology needs to pay more attention to descriptive statistics ('Table 1'; e.g., M, SD, reliability, correlations) when reporting and interpreting results. We agree that authors need to present a clear and transparent description of their data and that descriptive statistics and plots can be helpful in making sense of one's data and analyses (Tay et al., 2016). Many journals already require this. Although this information can be presented in the manuscript, more details can be placed in online supplements where there are fewer space limitations (e.g., detailed presentation and discussion of descriptive statistics, missing data and outliers, plots and diagrams, conceptual issues, and computer syntax). However, we strongly disagree with the claim that 'increasing complexity and diversity of data-analytic methods in organizational research has created several problems in our field' (p. 2). This claim suffers from two important oversights: (1) it neglects the crucial role of methodological fit, or the notion that theory, methods, and analyses need to be aligned, and (2) it neglects the fact that in I/O research, most constructs are not directly observable but need to be inferred indirectly though latent variable models. We expand on both issues, using examples to illustrate that the complexity and diversity of data-analytic methods is not a threat but a blessing for I/O research (and beyond). Finally, we conclude by highlighting the need for substantive-methodological synergies to solve some of the issues raised by Murphy (2021).
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- 2021
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31. The Involvement of the Posterior Cerebellum in Reconstructing and Predicting Social Action Sequences
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Naem Haihambo, Meijia Li, Elien Heleven, Min Pu, Natacha Deroost, Chris Baeken, Kris Baetens, Qianying Ma, Frank Van Overwalle, Psychology, Brain, Body and Cognition, Faculty of Psychology and Educational Sciences, Clinical sciences, Neuroprotection & Neuromodulation, Psychiatry, and Pharmaceutical and Pharmacological Sciences
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Cerebellum ,Magnetic Resonance Imaging ,Implicit learning ,Variety (cybernetics) ,Social actions ,medicine.anatomical_structure ,Mentalization ,Neurology ,Social neuroscience ,Action (philosophy) ,Theory of mind ,medicine ,Humans ,Neurology (clinical) ,Psychology ,Cognitive psychology - Abstract
Recent advances in social neuroscience have highlighted the critical role of the cerebellum and especially the posterior cerebellar Crus in social mentalizing (i.e., theory of mind). Research in the past 5 years has provided growing evidence supporting the view that the posterior cerebellum builds internal action models of our social interactions to predict how other people's actions will be executed, and what our most likely responses to these actions will be. This paper presents an overview of a series of fMRI experiments on novel tasks involving a combination of (a) the learning or generation of chronological sequences of social actions either in an explicit or implicit manner, which (b) require social mentalizing on another person's mental state such as goals, beliefs, and implied traits. Together, the results strongly confirm the central role of the posterior cerebellar Crus in identifying and automatizing action sequencing during social mentalizing, and in predicting future action sequences based on social mentalizing inferences about others. This research program has important implications: It provides for the first time (a) fruitful starting points for diagnosing and investigating social sequencing dysfunctions in a variety of mental disorders which have also been related to cerebellar dysfunctions, (b) provides the necessary tools for testing whether non-invasive neurostimulation targeting the posterior cerebellum has a causal effect on social functioning, and (c) whether these stimulation techniques and training programs guided by novel cerebellar social sequencing insights, can be exploited to increase posterior cerebellar plasticity in order to alleviate social impairments in mental disorders.
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- 2021
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32. Towards a more effective strategy to detect community-dwelling frail older adults: validation of risk factors
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Anne van der Vorst, Ellen Elisa De Roeck, Jan De Lepeleire, Birgitte Schoenmakers, Eva Dierckx, Liesbeth De Donder, Deborah Lambotte, Michaël Van der Elst, Health Services Research, RS: CAPHRI - R1 - Ageing and Long-Term Care, Psychology, Brain, Body and Cognition, Personality and Psychopathology, Psychopathology and Information Processing in Older Adults, Educational Science, Faculty of Psychology and Educational Sciences, and Belgian Ageing Studies
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Gerontology ,Frail Older Adults ,Prevalence ,Early detection ,Context (language use) ,Sample (statistics) ,DETERMINANTS ,Odds ,Validity ,03 medical and health sciences ,0302 clinical medicine ,PEOPLE ,Medicine ,030212 general & internal medicine ,MIGRANTS ,GENDER-DIFFERENCES ,Frailty ,business.industry ,Health Policy ,DISABILITY ,INTERDISCIPLINARY INTERVENTION ,MULTIFACTORIAL ,PROFILES ,Frailty assessment ,Detection ,Risk factors ,Older adults ,Business, Management and Accounting (miscellaneous) ,Marital status ,Human medicine ,HEALTH ,business ,030217 neurology & neurosurgery - Abstract
PurposeIn the context of early detection of frail older people, prior research found several risk factors of multidimensional frailty. The current study aims to validate these risk factors.Design/methodology/approachTwo data sets, Belgian Ageing Studies and Detection, Support and Care for older people: Prevention and Empowerment (BAS and D-SCOPE), in three Belgian municipalities (Ghent, Knokke-Heist and Thienen) were used and compared. The BAS data set (N = 1496) is a representative sample of community-dwelling older adults (60+), while the recruitment of the D-SCOPE sample (validation sample, N = 869) is based on risk factors (e.g. age, marital status, moved in the past 10 years). Frailty was measured with the comprehensive frailty assessment instrument (CFAI). The validity was examined by means of prevalence rates, distribution and the odds rates within both data sets.FindingsThe validation sample had an increase in the percentage of elderly who were mildly and highly frail for physical frailty (men: +17.0 percent point, women: +20.7 percent point), for psychological frailty (men: +13.4 percent point, women: +13.7 percent point), for social frailty (men: +24.8 percent point, women: +4.8 percent point) and environmental frailty (men: +24.2 percent point, women: +6.8 percent point). The present results indicate that the risk of being mildly or highly frail was higher in the validation sample in comparison with the BAS data.Originality/valueThe present study proved the validity of aforementioned risk factors. Selecting older people based on these risk factors proved to be an effective strategy for detecting frail older people.
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- 2021
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33. Bernheim’s Anamnestic Comparative Self-Assessment (ACSA)
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Peter Theuns, Dries Verlet, Brussels University Consultation Center, Psychology, Brain, Body and Cognition, and End-of-life Care Research Group
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self-anchoring scale ,Subjective Well-Being ,ACSA ,Anamnestic Comparative Self-Assessment ,Quality Of Life - Published
- 2022
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34. Effectiveness, satisfaction and meaningfulness of a 6-step detection and prevention program for frail community-dwelling older adults: a mixed-method evaluation
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D-SCOPE, Society and Ageing Research Lab, Brussels University Consultation Center, Psychology, Brain, Body and Cognition, Personality and Psychopathology, Educational Science, and Brussels Interdisciplinary Research centre on Migration and Minorities
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detection and prevention program ,Older People ,Frailty - Abstract
Background: As people age, the risk of becoming frail increases, often leading to negative outcomes and less well-being. Within the light of prevention, early detection and guidance to the right care and support is crucial. This study aimed to give an overview of the descriptive results of the D-SCOPE program and evaluate the process. Methods: The D-SCOPE program was developed as a detection and prevention program for frail community-dwelling older adults. The program creates a continuum of care and support, consisting of 6 steps: (1) Targeted case-finding using risk profiles for purposeful selection, (2) Preventive home-visit by an older volunteer, (3) Home visits by a professional, (4), Warm referral, (5) Monthly follow-up and (6) Long-term follow-up by home visit. The effectiveness of this program, in terms of satisfaction and meaningfulness, was studied quantitatively by means of a randomized controlled trial amongst 869 people with a frailty risk profile and qualitatively by 15 focus groups interviews. Results: The quantitative study revealed that 83.9% of the participants found the different home visits within the D-SCOPE program useful. The focus group interviews shed light on several issues and advantages: a more efficient case finding due to the applied risk factors for frailty, a more intensive tailor-made care and support due to the warm referral, the importance of both small-scaled and larger interventions based on the wishes irrespective of the state of frailty of the older persons, the focus on a strengths-based instead of a deficit-based approach and the follow up as being one of the greatest strengths of the project. However, to fully understand the benefits of the program a shift in mind from intervention to prevention is necessary. Conclusions: Our quantitative data show that most participants found the home visits meaningful and were satisfied with the intervention. The qualitative findings provided more insights into the experiences of the participants with the process. Based on these insights of the 6-step model of preventive home visits, municipalities and organizations can apply this model to carry out more targeted home visits
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- 2022
35. The Role of the Posterior Cerebellum in Dysfunctional Social Sequencing
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Chris Baeken, Cleo L. Crunelle, Xavier Noël, Frank Van Overwalle, Kris Baetens, Elien Heleven, Charles Kornreich, Marie-Anne Vanderhasselt, Maria Leggio, Salvatore Campanella, Psychology, Brain, Body and Cognition, Clinical sciences, Neuroprotection & Neuromodulation, Psychiatry, Faculty of Medicine and Pharmacy, Pharmaceutical and Pharmacological Sciences, and Faculty of Psychology and Educational Sciences
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Crus ,Mechanism (biology) ,Addiction ,media_common.quotation_subject ,Emotional mentalizing ,Dysfunctional family ,Mental disorders ,medicine.disease ,Non-invasive stimulation ,Social mentalizing ,Neurology ,Action (philosophy) ,Social neuroscience ,Social cognition ,Neurologie ,Cerebellum ,medicine ,Humans ,Autism ,Neurology (clinical) ,Social Behavior ,Psychology ,media_common ,Cognitive psychology ,Social behavior - Abstract
Recent advances in social neuroscience have highlighted the critical role of the cerebellum in social cognition, and especially the posterior cerebellum. Studies have supported the view that the posterior cerebellum builds internal action models of our social interactions to predict how other people’s actions will be executed and what our most likely responses are to these actions. This mechanism allows to better anticipate action sequences during social interactions in an automatic and intuitive way and to fine-tune these anticipations, making it easier to understand other’s social behaviors and mental states (e.g. beliefs, intentions, traits). In this paper, we argue that the central role of the posterior cerebellum in identifying and automatizing social action sequencing provides a fruitful starting point for investigating social dysfunctions in a variety of clinical pathologies, such as autism, obsessive–compulsive and bipolar disorder, depression, and addiction. Our key hypothesis is that dysfunctions of the posterior cerebellum lead to under- or overuse of inflexible social routines and lack of plasticity for learning new, more adaptive, social automatisms. We briefly review past research supporting this view and propose a program of research to test our hypothesis. This approach might alleviate a variety of mental problems of individuals who suffer from inflexible automatizations that stand in the way of adjustable and intuitive social behavior, by increasing posterior cerebellar plasticity using noninvasive neurostimulation or neuro-guided training programs., SCOPUS: no.j, info:eu-repo/semantics/published
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- 2022
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36. Going above and beyond for your Beliefs
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Y. Yang, I. Brans, T. Vantilborgh, Psychology, Faculty of Psychology and Educational Sciences, Brussels University Consultation Center, Brain, Body and Cognition, Work and Organisational Psychology, and Work and Organizational Psychology
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Organizational Behavior and Human Resource Management ,antecedent ,Pro-social rule breaking ,Human Factors and Ergonomics ,ideological psychological contract ,core self-evaluation - Abstract
Ideological psychological contracts (PC) describe perceived obligations that relate to an organization’s mission, values, and principles, and they relate closely to employees’ self-concept. The ideological currency is prevalent across various professions and organizations. In this study, we argue that employees engage in corrective behavior (i.e., pro-social rule breaking; PSRB) in response to large discrepancies between obligated and delivered ideological inducements (i.e., ideological PC breach). We measure breach obligated and delivered ideological inducements separately to examine their different effects on PSRB. Based on prior theoretical models, we examine core self-evaluation (i.e., CSE) and include perceptions of ideological PC breach and fulfillment as antecedents of PSRB, as well as the role of CSE in the relationship between perceptions of ideological PC breach and fulfillment and PSRB. Our results suggest that PSRB negatively relates to both the breach and fulfillment continua, and delivered ideological inducements relates more strongly to PSRB than obligated ideological inducements. Moreover, CSE does not moderate the relationship between ideological PC breach and fulfillment and PSRB. These results further our understanding of how ideological PCs shape employees’ behavior. By examining the moderating role of CSE, we advance the PC literature by showing that ideological PC breach and fulfillment perceptions are better antecedents of PSRB than CSE.
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- 2022
37. Participation of inpatients in multidisciplinary team meetings: An explorative study of mental healthcare workers' perception
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Kevin, Berben, Eva, Dierckx, Ann, Van Hecke, Sofie, Verhaeghe, Society and Ageing Research Lab, Brussels University Consultation Center, Psychology, Brain, Body and Cognition, and Personality and Psychopathology
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Patient Care Team ,Inpatients ,Cross-Sectional Studies ,Health Personnel ,Humans ,Perception ,Patient Participation ,Pshychiatric Mental Health - Abstract
Aim: To explore the perception of mental healthcare workers about participation of inpatients during multidisciplinary team meetings (MTMs) and to determine which demographic and contextual factors are associated with this perception. Methods: A cross-sectional multicentre study in 17 psychiatric hospitals with 701 mental healthcare workers was performed between 29 April and 19 May 2019. For measuring the perception of the mental healthcare workers, the Patient Participation during Multidisciplinary Team meetings Questionnaire was used. Results: 93 % of the mental healthcare workers indicate that they are willing to allow patients to participate in a MTM. Most mental healthcare workers prefer an active role for the patient when participating in a MTM (93 %) and a collaborative role for the patient when making decisions in a MTM (75 %). Level of education, discipline, experience with patient participation in MTMs, working in a team where patient participation is applied, and recent training on patient participation, are associated with the mental healthcare worker's perception on patient participation in MTMs. Conclusion: Mental healthcare workers report a great willingness to involve inpatients in MTMs. However, social workers, nurses, and pedagogues feel less competent and are less positive about the effects of patient participation in MTMs. Mental healthcare workers with recent training in patient participation and experience in patient participation in MTMs feel more competent and believe more often that the patient should fulfil a more autonomous role when participating in a MTM. These results can be used to understand and improve patient participation in MTMs in mental healthcare.
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- 2022
38. Impact of Sleep Fragmentation on Cognition and Fatigue
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Oumaïma Benkirane, Bérénice Delwiche, Olivier Mairesse, Philippe Peigneux, Faculty of Psychology and Educational Sciences, Brussels University Consultation Center, Psychology, and Brain, Body and Cognition
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Sleep/physiology ,sleep fragmentation ,cognitive fatigue ,cognitive functions ,polysomnography ,Health, Toxicology and Mutagenesis ,Public Health, Environmental and Occupational Health ,Humans ,Cognition/physiology ,Sleep Deprivation/psychology ,Wakefulness/physiology - Abstract
Sleep continuity and efficacy are essential for optimal cognitive functions. How sleep fragmentation (SF) impairs cognitive functioning, and especially cognitive fatigue (CF), remains elusive. We investigated the impact of induced SF on CF through the TloadDback task, measuring interindividual variability in working memory capacity. Sixteen participants underwent an adaptation polysomnography night and three consecutive nights, once in a SF condition induced by non-awakening auditory stimulations, once under restorative sleep (RS) condition, counterbalanced within-subject. In both conditions, participants were administered memory, vigilance, inhibition and verbal fluency testing, and for CF the TloadDback, as well as sleep questionnaires and fatigue and sleepiness visual analog scales were administered. Subjective fatigue increased and sleep architecture was altered after SF (reduced sleep efficiency, percentage of N3 and REM, number of NREM and REM phases) despite similar total sleep time. At the behavioral level, only inhibition deteriorated after SF, and CF similarly evolved in RS and SF conditions. In line with prior research, we show that SF disrupts sleep architecture and exerts a deleterious impact on subjective fatigue and inhibition. However, young healthy participants appear able to compensate for CF induced by three consecutive SF nights. Further studies should investigate SF effects in extended and/or pathological disruption settings.
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- 2022
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39. Prognostic potential of the cortisol response to therapeutic rTMS
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Cristian G. Giron, Bella B.B. Zhang, Chris Baeken, Georg S. Kranz, Brain, Body and Cognition, Clinical sciences, Neuroprotection & Neuromodulation, and Psychiatry
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Psychiatry and Mental health ,therapeutic rTMS ,cortisol response ,Biological Psychiatry - Published
- 2022
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40. Brainstem glucose metabolism predicts reward dependence scores in treatment-resistant major depression
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Chris Baeken, Guo-Rong Wu, Brain, Body and Cognition, Clinical sciences, Neuroprotection & Neuromodulation, and Psychiatry
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DIMENSIONS ,CORTEX ,medicine.medical_specialty ,MOOD DISORDERS ,HF-RTMS ,Treatment resistance ,Reticular formation ,treatment resistance ,03 medical and health sciences ,0302 clinical medicine ,CONNECTIVITY ,Internal medicine ,Medicine and Health Sciences ,medicine ,Applied Psychology ,18FDG ,business.industry ,TEMPERAMENT ,Dopaminergic ,Novelty seeking ,medicine.disease ,CHARACTER INVENTORY ,STATE ,030227 psychiatry ,Ventral tegmental area ,Psychiatry and Mental health ,Endocrinology ,medicine.anatomical_structure ,PET ,PERSONALITY-TRAIT ,Reward dependence ,reward dependence ,TCI ,depression ,Harm avoidance ,Temperament and Character Inventory ,(18)FDG PET ,Brainstem ,business ,SYSTEM ,030217 neurology & neurosurgery - Abstract
BackgroundIt has been suggested that individual differences in temperament could be involved in the (non-)response to antidepressant (AD) treatment. However, how neurobiological processes such as brain glucose metabolism may relate to personality features in the treatment-resistant depressed (TRD) state remains largely unclear.MethodsTo examine how brainstem metabolism in the TRD state may predict Cloninger's temperament dimensions Harm Avoidance (HA), Novelty Seeking (NS), and Reward Dependence (RD), we collected 18fluorodeoxyglucose positron emission tomography (18FDG PET) scans in 40 AD-free TRD patients. All participants were assessed with the Temperament and Character Inventory (TCI). We applied a multiple kernel learning (MKL) regression to predict the HA, NS, and RD from brainstem metabolic activity, the origin of respectively serotonergic, dopaminergic, and noradrenergic neurotransmitter (NT) systems.ResultsThe MKL model was able to significantly predict RD but not HA and NS from the brainstem metabolic activity. The MKL pattern regression model identified increased metabolic activity in the pontine nuclei and locus coeruleus, the medial reticular formation, the dorsal/median raphe, and the ventral tegmental area that contributed to the predictions of RD.ConclusionsThe MKL algorithm identified a likely metabolic marker in the brainstem for RD in major depression. Although 18FDG PET does not investigate specific NT systems, the predictive value of brainstem glucose metabolism on RD scores however indicates that this temperament dimension in the TRD state could be mediated by different monoaminergic systems, all involved in higher order reward-related behavior.
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- 2022
41. This is not who you are
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Min Pu, Qianying Ma, Elien Heleven, Jeroen Delplanque, Kris Baetens, Naem Haihambo, Chris Baeken, Natacha Deroost, Frank Van Overwalle, Psychology, Faculty of Psychology and Educational Sciences, Brain, Body and Cognition, Brussels University Consultation Center, Pharmaceutical and Pharmacological Sciences, Clinical sciences, Neuroprotection & Neuromodulation, and Psychiatry
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Behavioral Neuroscience ,Mentalization ,Reading ,Cerebellum ,Cognitive Neuroscience ,Humans ,Prefrontal Cortex ,Magnetic Resonance Imaging - Abstract
Recent research has indicated that the posterior cerebellum plays a crucial role in social cognition by encoding sequences of social actions. This study investigates its role in learning sequences of stereotype-implying actions by group members. We presented a set of five sentences that each described a group member who performed either stereotype-consistent or inconsistent actions. Participants were instructed to memorize the temporal order of the sentences and infer a common stereotype of the group. As a comparison, we included control conditions where participants had to memorize sequences of nonsocial consistent events or simply read stereotype-consistent sentences without memorizing their order. The results showed that the posterior cerebellum was strongly activated when participants were memorizing the order of the social actions, as opposed to simply reading these social actions. More importantly, when the social actions were inconsistent as opposed to consistent with the stereotype of the group, the posterior cerebellum was activated more strongly. This activation occurred together with cortical recruitment of the mentalizing network involving the dorsomedial prefrontal cortex (dmPFC) during social actions, and additionally the conflict monitoring network involving the lateral prefrontal cortex (PFC) and posterior medial frontal cortex (pmFC) during stereotype-inconsistent actions. These findings suggest that the cerebellum supports not only learning of low-level action sequences, but also of their high-level social implications.
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- 2022
42. A drop in cognitive performance, whodunit?
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Jeroen Van Cutsem, Peter Van Schuerbeek, Nathalie Pattyn, Hubert Raeymaekers, Johan De Mey, Romain Meeusen, Bart Roelands, Human Physiology and Sports Physiotherapy Research Group, Physiotherapy, Human Physiology and Anatomy, Artificial Intelligence supported Modelling in clinical Sciences, Supporting clinical sciences, Radiology, Medical Imaging, Brain, Body and Cognition, Body Composition and Morphology, and International Relations and Mobility
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Adult ,cognition ,Carryover effects ,Cognitive Neuroscience ,heart rate variability ,Brain ,Experimental and Cognitive Psychology ,Physical Therapy, Sports Therapy and Rehabilitation ,Mental Fatigue ,Cognitive fatigue ,Young Adult ,Neuropsychology and Physiological Psychology ,Heart Rate ,Radiology Nuclear Medicine and imaging ,Stroop Test ,Humans ,magnetic resonance imaging ,Female - Abstract
INTRODUCTION: The discussion on the mechanism(s) underlying mental fatigue is still ongoing. We want to reconfirm a performance-impairing effect of executing a lengthy cognitive task on the subsequent task, and determine how this effect is subtended by neurophysiological variations and subjective experience. METHODS: Twenty participants (12 females; age: 23 ± 1 y) performed an experimental (EXP) and a control trial (CON) in a randomized counter-balanced order. In both trials a 90-min cognitive task had to be performed (EXP, Stroop task; CON, documentary), that was preceded and followed up by a 10-min flanker task that was completed in the MRI scanner. Throughout the protocol, subjective self-evaluation, peripheral autonomic activation and metabolic measures, cognitive performance and functional brain imagery were recorded. Due to equipment issues, only 11 participants could be included in the analysis of the peripheral autonomic activation. RESULTS: Flanker performance dropped both in EXP and CON (p = .010). Heart rate variability increased in time, both in EXP and CON (p ≤ .047). A time-on-task related drop in Stroop performance (p = .007) and higher subjective mental fatigue was observed in EXP compared to CON (p < .001). Moreover, the BOLD signal of response inhibition-associated brain activity in corpus callosum, somatosensory association cortex and anterior cingulate cortex was reduced during the post-flanker task in EXP compared to CON (p < .001). Discussion Our results indicate two different processes: 1) A time-on-task effect as a peripheral physiological deactivation that coincided with the observed post-flanker performance drop both in EXP and CON; and 2) An increase in the level of subjective mental fatigue with prolonged performance on a 90-min Stroop task that is associated with a decrease in response inhibition-associated brain activity in both grey and white matter, specifically in the EXP-condition. CONCLUSION: Our results highlight the multifactoriality of carryover effects, in the present study increased parasympathetic activity was linked with the drop in performance.
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- 2022
43. A search for relevant contextual factors in intervention studies: a stepwise approach with online information
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Michael Van der Elst, Birgitte Schoenmakers, Eva Dierckx, Liesbeth De Donder, Ellen De Roeck, Daan Duppen, Bram Fret, Jos M G A Schols, Gertrudis I J M Kempen, Jan De Lepeleire, RS: CAPHRI - R1 - Ageing and Long-Term Care, Health Services Research, Brussels University Consultation Center, Psychology, Brain, Body and Cognition, Personality and Psychopathology, Participation and Learning in Detention, Belgian Ageing Studies, Educational Science, and Brussels research center for Innovation in Learning and Diversity
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HEALTH SERVICES ADMINISTRATION & MANAGEMENT ,PRIMARY CARE ,PEOPLE ,General Medicine ,Human medicine ,PUBLIC HEALTH - Abstract
ObjectiveThe aim of the present study is to describe a stepwise approach to study which contextual factors might moderate the effect of healthcare interventions and to test feasibility of this approach within the D-SCOPE project.DesignExploratory case study.SettingIn the D-SCOPE project, a complex intervention by means of home visits was set up to improve access to tailored care in three municipalities (Ghent, Knokke-Heist and Tienen).MethodsOne designed and tested an approach including five steps: (1) a theoretical/conceptual discussion of relevant contextual factor domains was held; (2) a search was done to find appropriate web-based public datasets which covered these topics with standardised information; (3) a list of all identified contextual factors was made (inventory); (4) to reduce the long list of contextual factors, a concise list of most relevant contextual factors was developed based on the opinion of two independent reviewers and (5) a nominal grouping technique (NGT) was applied.ResultsThree public web-based datasets were found resulting in an inventory of 157 contextual factors. After the selection by two independent reviewers, 41 contextual factors were left over and presented in a NGT which selected 10 contextual factors. The NGT included seven researchers, all familiar with the D-SCOPE intervention, with various educational backgrounds and expertise and lasted approximately 1 hour.ConclusionThe present study shows that a five-step approach is feasible to determine relevant contextual factors that might affect the results of an intervention study. Such information may be used to correct for in the statistical analyses and for interpretation of the outcomes of intervention studies.NCT03168204
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- 2022
44. Can transcranial direct current stimulation (tDCS) of the cerebellum improve implicit social and cognitive sequence learning?
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Qianying Ma, Min Pu, Meijia Li, Naem Haihambo, Kris Baetens, Elien Heleven, Natacha Deroost, Chris Baeken, Frank Van Overwalle, Psychology, Brain, Body and Cognition, Faculty of Psychology and Educational Sciences, Brussels University Consultation Center, Clinical sciences, Neuroprotection & Neuromodulation, and Psychiatry
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Clinical Psychology ,Brain stimulation ,Cerebellum ,Medicine and Health Sciences ,Social Sciences ,Serial reaction time task (SRT) ,Social sequencing ,Cognitive sequencing ,Transcranial direct current stimulation (tDCS) - Abstract
Accumulating evidence shows that the posterior cerebellum is involved in mentalizing inferences of social events by detecting sequence information in these events, and building and updating internal models of these sequences. By applying anodal and sham cerebellar transcranial direct current stimulation (tDCS) on the posteromedial cere-bellum of healthy participants, and using a serial reaction time (SRT) task paradigm, the current study examined the causal involvement of the cerebellum in implicitly learning sequences of social beliefs of others (Belief SRT) and non-social colored shapes (Cognitive SRT). Apart from the social or cognitive domain differences, both tasks were structurally identical. Results of anodal stimulation (i.e., 2 mA for 20 min) during the social Belief SRT task, did not show significant improvement in reaction times, however it did reveal generally faster responses for the Cognitive SRT task. This improved performance could also be observed after the cessation of stimulation after 30 min, and up to one week later. Our findings suggest a general positive effect of anodal cerebellar tDCS on implicit non-social Cognitive sequence learning, supporting a causal role of the cerebellum in this learning pro-cess. We speculate that the lack of tDCS modulation of the social Belief SRT task is due to the familiar and over -learned nature of attributing social beliefs, suggesting that easy and automatized tasks leave little room for improvement through tDCS.
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- 2022
45. Registered report: Does transcranial direct current stimulation of the primary motor cortex improve implicit motor sequence learning in Parkinson's disease?
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Frank Van Overwalle, Kris Baetens, Natacha Deroost, Mahyar Firouzi, Eva Swinnen, Chris Baeken, Brussels University Consultation Center, Rehabilitation Research, Physiotherapy, Human Physiology and Anatomy, Doctoraatsbegeleiding, Psychology, Brain, Body and Cognition, Clinical sciences, Neuroprotection & Neuromodulation, and Psychiatry
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Male ,0301 basic medicine ,Serial reaction time ,medicine.medical_specialty ,Motor Cortex/physiology ,Parkinson's disease ,medicine.medical_treatment ,Transcranial Direct Current Stimulation ,Procedural memory ,03 medical and health sciences ,Cellular and Molecular Neuroscience ,Cognition ,0302 clinical medicine ,Physical medicine and rehabilitation ,Double-Blind Method ,Basal ganglia ,Reaction Time ,medicine ,Learning ,Humans ,Cognition/physiology ,Aged ,Parkinson Disease/physiopathology ,Transcranial Direct Current Stimulation/methods ,Transcranial direct-current stimulation ,business.industry ,Motor Cortex ,Parkinson Disease ,Learning/physiology ,Middle Aged ,medicine.disease ,030104 developmental biology ,Reaction Time/physiology ,Brain stimulation ,Female ,Sequence learning ,Primary motor cortex ,aged, 80 and over ,business ,Photic Stimulation ,030217 neurology & neurosurgery ,Photic Stimulation/methods - Abstract
Implicit motor sequence learning (IMSL) is a cognitive function that is known to be directly associated with impaired motor function in Parkinson's disease (PD). Research on healthy young participants shows the potential for transcranial direct current stimulation (tDCS), a noninvasive brain stimulation technique, over the primary motor cortex (M1) to enhance IMSL. tDCS has direct effects on the underlying cortex, but also induces distant (basal ganglia) network effects-hence its potential value in PD, a prime model of basal ganglia dysfunction. To date, only null effects have been reported in persons with PD. However, these studies did not determine the reacquisition effects, although previous studies in healthy young adults suggest that tDCS specifically exerts its beneficial effects on IMSL on reacquisition rather than acquisition. In the current study, we will therefore establish possible reacquisition effects, which are of a particular interest, as long-term effects are vital for the successful functional rehabilitation of persons with PD. Using a sham-controlled, counterbalanced design, we will investigate the potential of tDCS delivered over M1 to enhance IMSL, as measured by the serial reaction time task, in persons with PD and a neurologically healthy age- and sex-matched control (HC) group. Multilevel Mixed Models will be implemented to analyze the sequence-specific aspect of IMSL (primary outcome) and general learning (secondary outcome). We will determine not only the immediate effects that may occur concurrently with the application of tDCS but also the short-term (5 min post-tDCS) and long-term (1 week post-tDCS) reacquisition effects.
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- 2021
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46. Group Intervention ‘Drop it!’ Decreases Repetitive Negative Thinking in Major Depressive Disorder and/or Generalized Anxiety Disorder: A Randomised Controlled Study
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Gilbert Lemmens, Jonathan Remue, Dirk Van den Abbeele, Rudi De Raedt, Roland Rogiers, Roos Colman, Chris Baeken, Edward R. Watkins, Brain, Body and Cognition, Clinical sciences, Neuroprotection & Neuromodulation, and Psychiatry
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050103 clinical psychology ,Generalized anxiety disorder ,media_common.quotation_subject ,medicine.medical_treatment ,Experimental and Cognitive Psychology ,law.invention ,03 medical and health sciences ,Metacognitive therapy ,0302 clinical medicine ,Randomized controlled trial ,law ,medicine ,0501 psychology and cognitive sciences ,media_common ,major depressive disorder ,05 social sciences ,medicine.disease ,030227 psychiatry ,Group intervention ,Cognitive behavioral therapy ,Psychiatry and Mental health ,Clinical Psychology ,Repetitive negative thinking ,Cognitive behavior therapy ,Randomized Controlled Trial ,Rumination ,Major depressive disorder ,Anxiety ,Worry ,medicine.symptom ,Psychology ,Clinical psychology - Abstract
Background: Repetitive negative thinking (RNT) is considered to be an important transdiagnostic factor in the onset, course and recurrence of both depressive and anxiety disorders. This study aimed to investigate whether an add-on group intervention ‘Drop it’, compared to treatment as usual, would improve RNT, anxiety and depressive symptoms, as well as quality of life and self-esteem of patients with Major Depressive Disorder (MDD) and/or Generalized Anxiety Disorder (GAD). Methods: Eighty patients were randomly allocated to 8 sessions of group intervention (n = 45) or a delayed treatment control group (n = 35). Both conditions continued their ongoing mental health care. Assessments took place before randomization, 12 weeks later (after group intervention) and at 3- and 9- months follow-up. Results: Although all outcomes improved after the intervention, only the uncontrollability of rumination, worrying, distancing oneself from one’s thoughts, and quality of life remained statistically significant after Bonferroni correction compared to the delayed treatment control group. Conclusions: Group intervention improves RNT and quality of life of patients treated for MDD and/or GAD. Improvements remain stable until 9 months after treatment. Limitations of the study included the small sample size, the lack of a long-term follow-up in the delayed treatment control group and the inclusion of highly educated patients with mainly high comorbid generalized anxiety disorder and depression.
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- 2021
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47. Change in unit‐level job attitudes following strategic interventions: A meta‐analysis of longitudinal studies
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Daniel Balliet, Omar Solinger, Tim Vantilborgh, Jeff Joireman, Management and Organisation, Amsterdam Business Research Institute, Social Psychology, IBBA, Psychology, Brain, Body and Cognition, and Work and Organizational Psychology
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organizational change ,Organizational Behavior and Human Resource Management ,longitudinal ,Sociology and Political Science ,analysis ,Restructuring ,temporal ,Psychological intervention ,Cost cutting ,skin and connective tissue diseases ,Unit level ,General Psychology ,Applied Psychology ,job satisfaction ,commitment ,meta‐ ,SDG 8 - Decent Work and Economic Growth ,Job attitude ,unit level ,meta-analysis ,job attitudes ,social exchange ,Social exchange theory ,Meta-analysis ,Job satisfaction ,Demographic economics ,sense organs ,Psychology ,set point ,HRM - Abstract
The present meta-analysis tests how cost- and people-oriented strategic interventions impact temporal-dynamic changes in unit-level job attitudes within organizations. Analyses are based on 573 effect sizes across 137 longitudinal studies containing unit-level change in job attitudes across three time periods (pre-change, during change, and post-change). Results reveal that unit-level job attitudes (a) decline during cost-oriented changes (e.g., restructuring) and remain at lower levels following the changes (supporting a sustained change model); (b) increase during people-oriented changes (i.e., HRM investments) and remain at higher levels following the interventions (consistent with a sustained change model); and (c) remain unchanged over time when cost- and people-oriented interventions are combined. Tests of a process model further reveal that cost-oriented (people-oriented) interventions impact unit-level job attitudes by reducing (increasing) perceived support (relative to a no intervention control). The pattern of findings suggests that long-term, unit-level change in job attitudes can be anticipated to follow from strategic interventions, although some of the negative impact of cost cutting can be mitigated by maintaining perceptions of support.
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- 2021
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48. Relating within-person personality variability to organizational citizenship behavior and counterproductive work behavior: A resource-based perspective
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Juul Vossen, Joeri Hofmans, Psychology, Faculty of Psychology and Educational Sciences, Work and Organizational Psychology, and Brain, Body and Cognition
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Organizational citizenship behavior ,workperformance ,Social Psychology ,Resource based ,media_common.quotation_subject ,Field (Bourdieu) ,05 social sciences ,Within person ,Perspective (graphical) ,within-person personality variability ,050109 social psychology ,relative variability index ,Resource (project management) ,0502 economics and business ,Personality ,0501 psychology and cognitive sciences ,Psychology ,Social psychology ,Counterproductive work behavior ,050203 business & management ,media_common - Abstract
Research on the effects of within-person personality variability has mainly focused on the consequences for subjective well-being. Drawing on a resource-based approach, we extend this field to the work domain, expecting that since deviating from one’s average trait level is resource intensive, it should relate negatively to behaviors that require the investment of additional resources, such as organizational citizenship behavior (OCB), while it should relate positively to behaviors that replenish one’s resources, such as counterproductive work behavior. Using two personality dimensions that are predictive for work-performance (conscientiousness and core self-evaluations), and a new variability index that is not confounded by the mean, we find an effect of personality variability on negative performance outcomes (counterproductive work behavior), while no relation is found with positive forms of extra-role performance (organizational citizenship behavior). These results were replicated across three separate experience sampling studies, confirming that, while within-person personality variability is related to performance, those relationships are relatively weak and they do not hold for every performance facet.
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- 2021
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49. Translating trait to state assessment: The case of grandiose narcissism
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Fien Heyde, Bart Wille, Evy Kuijpers, Jasmine Vergauwe, Joeri Hofmans, Psychology, Work and Organizational Psychology, and Brain, Body and Cognition
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Multidisciplinary ,general ,Social Sciences - Abstract
Although interest in within-person variability in grandiose narcissism is growing, measurement tools are lacking that allow studying fluctuations in this personality characteristic in a differentiated manner (i.e., distinguishing narcissistic admiration and rivalry). This study explores whether a measurement approach using the six-item version of the Narcissistic Grandiosity Scale (NGS Rosenthal et al. (2007)) and six additional newly formulated adjectives allows assessing state admiration and rivalry. Structural characteristics and convergent validity of this approach were examined in an experience sampling study in which 114 adults participated, providing state assessments twice a day (total number of observations = 1306). Multilevel bifactor analyses revealed three factors (i.e., one general and two specific factors) at both within- and between-person levels. Further, admiration and rivalry showed a pattern of within-person associations with fluctuations in self-esteem and Big Five states that were consistent with theoretical expectations. Finally, average state admiration and average state rivalry correlated substantively with trait measures of these respective constructs assessed one week prior to the experience sampling design.
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- 2023
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50. Severity Indices of Personality Problems-Short Form in Old-Age Psychiatry
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Gina Rossi, Sebastiaan P J van Alphen, Jill Lobbestael, Arjan C Videler, Daniel L. Segal, Barbera E van Reijswoud, Inge Debast, Section Clinical Psychology, RS: FPN CPS III, Tranzo, Scientific center for care and wellbeing, Medical and Clinical Psychology, Geestelijke Gezondheidszorg, Psychology, Personality and Psychopathology, Psychopathology and Information Processing in Older Adults, Brain, Body and Cognition, and Metajuridica
- Subjects
Male ,Personality Tests ,Self Disclosure ,Psychometrics ,DISORDERS ,Health, Toxicology and Mutagenesis ,media_common.quotation_subject ,FEATURES ,Geriatric Psychiatry ,MEDLINE ,macromolecular substances ,Personality Disorders ,Severity of Illness Index ,Arts and Humanities (miscellaneous) ,Surveys and Questionnaires ,Severity of illness ,Old age psychiatry ,Humans ,Personality ,DIAGNOSTIC-ACCURACY ,PROBLEMS SIPP-118 ,Reliability (statistics) ,Aged ,media_common ,CONSTRUCT-VALIDITY ,Aged, 80 and over ,ISSUES ,CHALLENGES ,musculoskeletal, neural, and ocular physiology ,Reproducibility of Results ,Construct validity ,ADULTS ,Middle Aged ,Diagnostic and Statistical Manual of Mental Disorders ,Clinical Psychology ,nervous system ,Self-disclosure ,Personality problems ,Female ,Self Report ,Psychology ,Clinical psychology - Abstract
The Severity Indices of Personality Problems (SIPP; Verheul et al., 2008) is a popular self-report questionnaire that measures severity of maladaptive personality functioning. Two studies demonstrated the utility of the short form (SIPP-SF) among older adults but validation in clinical settings is lacking. Therefore, we examined the psychometric properties of the SIPP-SF in a large sample of older adult Dutch outpatients (N = 124; age range = 60-85 years, M = 69.8, SD = 5.3). The SIPP-SF domains showed good to excellent internal reliability (Cronbach's α = .75-.91) and effectively discriminated between participants with and without a personality disorder, as assessed with the Structured Clinical Interview for DSM-IV Axis II Personality Disorders (SCID-II). Convergent validity of the SIPP-SF was examined with instruments for measuring personality pathology among older adults (Informant Personality questionnaire [HAP]; Gerontological Personality Disorders Scale [GPS]). The GPS generally correlated with the SIPP-SF domains in expected directions, with small to large effect sizes. For the HAP, only 1 scale correlated with all SIPP-SF domains. No associations were found between the SIPP-SF and psychiatric symptomatology as measured by the Brief Symptom Inventory (BSI). The SIPP-SF appears to be a promising instrument for assessing maladaptive personality functioning among older adult outpatients.
- Published
- 2021
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