4 results on '"Braganó, P."'
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2. Nomenclature for renal replacement therapy and blood purification techniques in critically ill patients: practical applications
- Author
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Villa, Gianluca, Neri, M., Bellomo, R., Cerda, J., De Gaudio, Angelo Raffaele, De Rosa, S., Garzotto, F., Honore, P. M., Kellum, J., Lorenzin, A., Payen, D., Ricci, Z., Samoni, S., Vincent, J. L., Wendon, J., Zaccaria, M., Ronco, C., Bagshaw, S. M., Balducci, A., Baldwin, I., Barbarigo, F., Braganó, P., Braunsky, J., Calletti, F., Chawla, L., Di Somma, S., Doi, K., Dosil Rosende, P., Emmett, M., Fecondini, L., Galavotti, D., Gibney, N., Goldstein, S. L., Guadagni, G., Honorè, P., Hoste, E., Inadome, S., Kashani, K., Katz, N., Kenley, R., Kobayashi, Y., Lannoy, J., Lewington, A., Mariano, F., McCullough, P. A., Mehta, R. L., Menneguerre, J., Mettifogo, M., Ostermann, M., Pani, A., Pirazzoli, P., Pohlmeier, R., Pouchoulin, D., Rosner, M., Seamann, M., Shaw, A., Tolwani, A., Supporting clinical sciences, and Internal Medicine Specializations
- Subjects
CRRT machine ,HIGH-VOLUME HEMOFILTRATION ,INTENSIVE-CARE-UNIT ,medicine.medical_treatment ,Continuous plasmafiltration coupled with adsorption ,continuous veno-venous hemodiafiltration ,continuous veno-venous hemodialysis ,continuous veno-venous hemofiltration ,hemoperfusion ,high volume hemofiltration ,pressure sensor ,pump ,terminology ,critical care and Intensive care medicine ,030232 urology & nephrology ,Review ,Continuous veno-venous hemofiltration ,Critical Care and Intensive Care Medicine ,High volume hemofiltration ,0302 clinical medicine ,Continuous veno-venous hemodiafiltration ,DIALYSIS ,Medicine and Health Sciences ,FAILURE ,Medicine(all) ,Acute kidney injury ,Acute Kidney Injury ,RANDOMIZED CONTROLLED-TRIAL ,Terminology ,Continuous veno-venous hemodialysis ,Renal Replacement Therapy ,medicine.symptom ,medicine.medical_specialty ,Consensus ,Critical Care ,Pressure sensor ,POLYMYXIN-B HEMOPERFUSION ,Critical Illness ,ACUTE KIDNEY INJURY ,Hemodiafiltration ,Extracorporeal ,EXTRACORPOREAL MEMBRANE-OXYGENATION ,Sepsis ,03 medical and health sciences ,Hemofiltration ,medicine ,Extracorporeal membrane oxygenation ,Humans ,Renal replacement therapy ,Intensive care medicine ,Septic shock ,business.industry ,Hemoperfusion ,Pump ,SEPTIC SHOCK ,Organ dysfunction ,Généralités ,030208 emergency & critical care medicine ,medicine.disease ,LIVER SUPPORT ,business - Abstract
This article reports the conclusions of the second part of a consensus expert conference on the nomenclature of renal replacement therapy (RRT) techniques currently utilized to manage acute kidney injury and other organ dysfunction syndromes in critically ill patients. A multidisciplinary approach was taken to achieve harmonization of definitions, components, techniques, and operations of the extracorporeal therapies. The article describes the RRT techniques in detail with the relevant technology, procedures, and phases of treatment and key aspects of volume management/fluid balance in critically ill patients. In addition, the article describes recent developments in other extracorporeal therapies, including therapeutic plasma exchange, multiple organ support therapy, liver support, lung support, and blood purification in sepsis. This is a consensus report on nomenclature harmonization in extracorporeal blood purification therapies, such as hemofiltration, plasma exchange, multiple organ support therapies, and blood purification in sepsis., 0, SCOPUS: re.j, info:eu-repo/semantics/published
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- 2016
3. Nomenclature for renal replacement therapy in acute kidney injury: Basic principles
- Author
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Neri, Mauro, Villa, Gianluca, Garzotto, Francesco, Bagshaw, Sean, Bellomo, ELENA MARIA RITA, Cerda, Jorge, Ferrari, Fiorenza, Guggia, Silvia, Joannidis, Michael, Kellum, John, Kim, Jeong Chul, Mehta, Ravindra L., Ricci, Zaccaria, Trevisani, Alberto, Marafon, Silvio, Clark, William R., Vincent, Jean Louis, Ronco, Claudio, Bagshaw, S. M., Balducci, Alessandro, Baldwin, I., Barbarigo, F., Bellomo, R., Braganó, P., Braunsky, J., Calletti, F., Cerda, J., Chawla, L., De Rosa, S., Di Somma, S., Doi, K., Dosil Rosende, P., Emmett, M., Fecondini, L., Galavotti, D., Kellum, J., Garzotto, F., Lorenzin, A., Neri, M., Ronco, C., Goldstein, S. L., Guadagni, G., Honoré, P., Hoste, E., Kashani, K., Katz, N., Kenley, R., Lannoy, J., Lewington, A., Mariano, F., Mccullough, P. A., Mehta, R. L., Menneguerre, J., Mettifogo, M., Ostermann, M., Pani, A., Pirazzoli, P., Pohlmeier, R., Pouchoulin, D., Ricci, Z., Rosner, M., Seamann, M., Shaw, A., Tolwani, A., Villa, G., Vincent, J. L., and Wendon, J.
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medicine.medical_specialty ,CRRT efficiency ,medicine.medical_treatment ,Critical Illness ,030232 urology & nephrology ,Transmembrane pressure ,Ultrafiltration ,CRRT modalities ,Review ,030204 cardiovascular system & hematology ,urologic and male genital diseases ,Clearance ,Convection ,CRRT membranes ,Diffusion ,Dose ,Terminology ,Critical Care and Intensive Care Medicine ,Extracorporeal ,03 medical and health sciences ,0302 clinical medicine ,Renal Dialysis ,Terminology as Topic ,medicine ,Humans ,Renal replacement therapy ,Intensive care medicine ,Acute Kidney Injury ,Renal Replacement Therapy ,business.industry ,Critically ill ,Consensus conference ,Acute kidney injury ,Généralités ,medicine.disease ,Critical illness ,business - Abstract
This article reports the conclusions of a consensus expert conference on the basic principles and nomenclature of renal replacement therapy (RRT) currently utilized to manage acute kidney injury (AKI). This multidisciplinary consensus conference discusses common definitions, components, techniques, and operations of the machines and platforms used to deliver extracorporeal therapies, utilizing a "machine-centric" rather than a "patient-centric" approach. We provide a detailed description of the performance characteristics of membranes, filters, transmembrane transport of solutes and fluid, flows, and methods of measurement of delivered treatment, focusing on continuous renal replacement therapies (CRRT) which are utilized in the management of critically ill patients with AKI. This is a consensus report on nomenclature harmonization for principles of extracorporeal renal replacement therapies. Devices and operations are classified and defined in detail to serve as guidelines for future use of terminology in papers and research., 0, SCOPUS: re.j, info:eu-repo/semantics/published
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- 2016
4. Urinary and serum hormones profiles after testosterone enanthate administration in male hypogonadism: Concerns on the detection of doping with testosterone in treated hypogonadal athletes
- Author
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Luigi, L., Sgrò, P., Romanelli, F., Mazzarino, M., Donati, F., Braganó, M., Bianchini, S., Fierro, V., Casasco, M., Botrè, F., and Lenzi, A.
- Abstract
Objective: To describe serum and urinary hormones, androgens metabolites and testosterone/epitestosterone ratio profiles after testosterone administration in male hypogonadal volunteers, and to evaluate their possible usefulness in detecting doping with testosterone in treated hypogonadal athletes. Design: Controlled open label design vs placebo; pharmacokinetic study. Participants: Ten male volunteers affected by severe hypogonadism (serum testosterone <2.31 ng/ml). Interventions and main outcome measures: Serum and urinary parameters were evaluated, by radioimmunoassay and gas chromatography-mass spectrometry, before and at different time points for 7/3 weeks after a single administration of testosterone enanthate (250 mg) or placebo, respectively. Results: As partially known, testosterone administration increased, with great individual variability, urinary concentrations of glucuronide testosterone, androsterone, etiocholanolone, 5α-androstane-3α,17β-diol, 5β-androstane-3α,17β-diol, testosterone/epitestosterone and testosterone/LH ratios; and decreased epitestosterone and 5α-androstane-3β,17β-diol/5β-an-drostane-3α,17β-diol ratio. Serum testosterone and dihydrotestosterone increased in all volunteers, and concentrations higher than the upper reference limits were observed in many volunteers until 2 weeks after testosterone administration. Conclusion: Whereas the observed prolonged hyperandrogenism partially limited data interpretation, the reported characteristics of variation of urinary parameters might be used to suspect testosterone misuse in hypogonadal athletes treated with testosterone enanthate. In this sense, while the actual threshold for testosterone/epitestosterone ratio was confirmed to be of reduced usefulness, we suggest a contemporary evaluation of whole urinary androgen metabolites profile and serum androgens, at specific time points after testosterone enanthate administration. Moreover, an adequate tailoring of treatment, to avoid transitory hyperandrogenism, is highly advisable. Further studies on strategies for detecting doping with testosterone in hypogonadal athletes are warranted.
- Published
- 2009
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