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503 results on '"Bracco, C."'

1. A critically prolonged avalanche burial with recorded cardiac electrical activity and complete recovery - a case report

Author: Bracco, C., Strapazzon, G., Sciolla, A., Dupuis, A., Lauria, G., and Fenoglio, L.
Published: 2024
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2. Injection and Beam Dump Systems

Author: Bracco, C., primary, Barnes, M. J., additional, Bartmann, W., additional, Calviani, M., additional, Perez, D. Carbajo, additional, Carlier, E., additional, Ducimetiere, L., additional, Frankl, M. I., additional, Goddard, B., additional, Jowett, J., additional, Lechner, A., additional, Magnin, N., additional, Marcone, A. Perillo, additional, Polzin, T., additional, Rizzoglio, V., additional, Senaj, V., additional, Vega, L., additional, Vlachodimitropoulos, V., additional, and Wiesner, C., additional
Published: 2024
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3. Design and behaviour of the Large Hadron Collider external beam dumps capable of receiving 539 MJ/dump

Author: Maestre, J., Torregrosa, C., Kershaw, K., Bracco, C., Coiffet, T., Ferrari, M., Ximenes, R. Franqueira, Gilardoni, S., Grenier, D., Lechner, A., Maire, V., Ruiz, J. M. Martin, Matheson, E., Solieri, N., Marcone, A. Perillo, Polzin, T., Rizzoglio, V., Senajova, D., Sharp, C., Timmins, M., and Calviani, M.
Subjects: Physics - Accelerator Physics, Physics - Applied Physics, Physics - Instrumentation and Detectors
Abstract: Two 6-t beam dumps, made of a graphite core encapsulated in a stainless steel vessel, are used to absorb the energy of the two Large Hadron Collider (LHC) intense proton beams during operation of the accelerator. Operational issues started to appear in 2015 during LHC Run 2 (2014-2018) as a consequence of the progressive increase of the LHC beam kinetic energy, necessitating technical interventions in the highly radioactive areas around the dumps. Nitrogen gas leaks appeared after highly energetic beam impacts and instrumentation measurements indicated an initially unforeseen movement of the dumps. A computer modelling analysis campaign was launched to understand the origin of these issues, including both Monte Carlo simulations to model the proton beam interaction as well as advanced thermo-mechanical analyses. The main findings were that the amount of instantaneous energy deposited in the dump vessel leads to a strong dynamic response of the whole dump and high accelerations (above 2000g). Based on these findings, an upgraded design, including a new support system and beam windows, was implemented to ensure the dumps' compatibility with the more intense beams foreseen during LHC Run 3 (2022-2025) of 539 MJ per beam. In this paper an integral overview of the operational behaviour of the dumps and the upgraded configurations are discussed., Comment: 36 pages, 21 figures, to be submitted to Journal of Instrumentation (JINST)
Published: 2021
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4. The Large Hadron-Electron Collider at the HL-LHC

Author: Agostini, P., Aksakal, H., Alekhin, S., Allport, P. P., Andari, N., Andre, K. D. J., Angal-Kalinin, D., Antusch, S., Bella, L. Aperio, Apolinario, L., Apsimon, R., Apyan, A., Arduini, G., Ari, V., Armbruster, A., Armesto, N., Auchmann, B., Aulenbacher, K., Azuelos, G., Backovic, S., Bailey, I., Bailey, S., Balli, F., Behera, S., Behnke, O., Ben-Zvi, I., Benedikt, M., Bernauer, J., Bertolucci, S., Biswal, S. S., Blümlein, J., Bogacz, A., Bonvini, M., Boonekamp, M., Bordry, F., Boroun, G. R., Bottura, L., Bousson, S., Bouzas, A. O., Bracco, C., Bracinik, J., Britzger, D., Brodsky, S. J., Bruni, C., Brüning, O., Burkhardt, H., Cakir, O., Calaga, R., Caldwell, A., Calıskan, A., Camarda, S., Catalan-Lasheras, N. C., Cassou, K., Cepila, J., Cetinkaya, V., Chetvertkova, V., Cole, B., Coleppa, B., Cooper-Sarkar, A., Cormier, E., Cornell, A. S., Corsini, R., Cruz-Alaniz, E., Currie, J., Curtin, D., D'Onofrio, M., Dainton, J., Daly, E., Das, A., Das, S. P., Dassa, L., de Blas, J., Rose, L. Delle, Denizli, H., Deshpande, K. S., Douglas, D., Duarte, L., Dupraz, K., Dutta, S., Efremov, A. V., Eichhorn, R., Eskola, K. J., Ferreiro, E. G., Fischer, O., Flores-Sánchez, O., Forte, S., Gaddi, A., Gao, J., Gehrmann, T., Ridder, A. Gehrmann-De, Gerigk, F., Gilbert, A., Giuli, F., Glazov, A., Glover, N., Godbole, R. M., Goddard, B., Gonçalves, V., Gonzalez-Sprinberg, G. A., Goyal, A., Grames, J., Granados, E., Grassellino, A., Gunaydin, Y. O., Guo, Y. C., Guzey, V., Gwenlan, C., Hammad, A., Han, C. C., Harland-Lang, L., Haug, F., Hautmann, F., Hayden, D., Hessler, J., Helenius, I., Henry, J., Hernandez-Sanchez, J., Hesari, H., Hobbs, T. J., Hod, N., Hoffstaetter, G. H., Holzer, B., Honorato, C. G., Hounsell, B., Hu, N., Hug, F., Huss, A., Hutton, A., Islam, R., Iwamoto, S., Jana, S., Jansova, M., Jensen, E., Jones, T., Jowett, J. M., Kaabi, W., Kado, M., Kalinin, D. A., Karadeniz, H., Kawaguchi, S., Kaya, U., Khalek, R. A., Khanpour, H., Kilic, A., Klein, M., Klein, U., Kluth, S., Köksal, M., Kocak, F., Korostelev, M., Kostka, P., Krelina, M., Kretzschmar, J., Kuday, S., Kulipanov, G., Kumar, M., Kuze, M., Lappi, T., Larios, F., Latina, A., Laycock, P., Lei, G., Levitchev, E., Levonian, S., Levy, A., Li, R., Li, X., Liang, H., Litvinenko, V., Liu, M., Liu, T., Liu, W., Liu, Y., Liuti, S., Lobodzinska, E., Longuevergne, D., Luo, X., Ma, W., Machado, M., Mandal, S., Mäntysaari, H., Marhauser, F., Marquet, C., Martens, A., Martin, R., Marzani, S., McFayden, J., Mcintosh, P., Mellado, B., Meot, F., Milanese, A., Milhano, J. G., Militsyn, B., Mitra, M., Moch, S., Najafabadi, M. Mohammadi, Mondal, S., Moretti, S., Morgan, T., Morreale, A., Nadolsky, P., Navarra, F., Nergiz, Z., Newman, P., Niehues, J., Nissen, E. A., Nowakowski, M., Okada, N., Olivier, G., Olness, F., Olry, G., Osborne, J. A., Ozansoy, A., Pan, R., Parker, B., Patra, M., Paukkunen, H., Peinaud, Y., Pellegrini, D., Perez-Segurana, G., Perini, D., Perrot, L., Pietralla, N., Pilicer, E., Pire, B., Pires, J., Placakyte, R., Poelker, M., Polifka, R., Polini, A., Poulose, P., Pownall, G., Pupkov, Y. A., Queiroz, F. S., Rabbertz, K., Radescu, V., Rahaman, R., Rai, S. K., Raicevic, N., Ratoff, P., Rashed, A., Raut, D., Raychaudhuri, S., Repond, J., Rezaeian, A. H., Rimmer, R., Rinolfi, L., Rojo, J., Rosado, A., Ruan, X., Russenschuck, S., Sahin, M., Salgado, C. A., Sampayo, O. A., Satendra, K., Satyanarayan, N., Schenke, B., Schirm, K., Schopper, H., Schott, M., Schulte, D., Schwanenberger, C., Sekine, T., Senol, A., Seryi, A., Setiniyaz, S., Shang, L., Shen, X., Shipman, N., Sinha, N., Slominski, W., Smith, S., Solans, C., Song, M., Spiesberger, H., Stanyard, J., Starostenko, A., Stasto, A., Stocchi, A., Strikman, M., Stuart, M. J., Sultansoy, S., Sun, H., Sutton, M., Szymanowski, L., Tapan, I., Tapia-Takaki, D., Tanaka, M., Tang, Y., Tasci, A. T., Ten-Kate, A. T., Thonet, P., Tomas-Garcia, R., Tommasini, D., Trbojevic, D., Trott, M., Tsurin, I., Tudora, A., Cakir, I. Turk, Tywoniuk, K., Vallerand, C., Valloni, A., Verney, D., Vilella, E., Walker, D., Wallon, S., Wang, B., Wang, K., Wang, X., Wang, Z. S., Wei, H., Welsch, C., Willering, G., Williams, P. H., Wollmann, D., Xiaohao, C., Xu, T., Yaguna, C. E., Yamaguchi, Y., Yamazaki, Y., Yang, H., Yilmaz, A., Yock, P., Yue, C. X., Zadeh, S. G., Zenaiev, O., Zhang, C., Zhang, J., Zhang, R., Zhang, Z., Zhu, G., Zhu, S., Zimmermann, F., Zomer, F., Zurita, J., and Zurita, P.
Subjects: High Energy Physics - Experiment, High Energy Physics - Phenomenology, Nuclear Experiment, Nuclear Theory
Abstract: The Large Hadron electron Collider (LHeC) is designed to move the field of deep inelastic scattering (DIS) to the energy and intensity frontier of particle physics. Exploiting energy recovery technology, it collides a novel, intense electron beam with a proton or ion beam from the High Luminosity--Large Hadron Collider (HL-LHC). The accelerator and interaction region are designed for concurrent electron-proton and proton-proton operation. This report represents an update of the Conceptual Design Report (CDR) of the LHeC, published in 2012. It comprises new results on parton structure of the proton and heavier nuclei, QCD dynamics, electroweak and top-quark physics. It is shown how the LHeC will open a new chapter of nuclear particle physics in extending the accessible kinematic range in lepton-nucleus scattering by several orders of magnitude. Due to enhanced luminosity, large energy and the cleanliness of the hadronic final states, the LHeC has a strong Higgs physics programme and its own discovery potential for new physics. Building on the 2012 CDR, the report represents a detailed updated design of the energy recovery electron linac (ERL) including new lattice, magnet, superconducting radio frequency technology and further components. Challenges of energy recovery are described and the lower energy, high current, 3-turn ERL facility, PERLE at Orsay, is presented which uses the LHeC characteristics serving as a development facility for the design and operation of the LHeC. An updated detector design is presented corresponding to the acceptance, resolution and calibration goals which arise from the Higgs and parton density function physics programmes. The paper also presents novel results on the Future Circular Collider in electron-hadron mode, FCC-eh, which utilises the same ERL technology to further extend the reach of DIS to even higher centre-of-mass energies., Comment: 373 pages, many figures, to be published by J. Phys. G
Published: 2020
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5. Experimental observation of proton bunch modulation in a plasma, at varying plasma densities

Author: Adli, E., Ahuja, A., Apsimon, O., Apsimon, R., Bachmann, A. -M., Barrientos, D., Barros, M. M., Batkiewicz, J., Batsch, F., Bauche, J., Olsen, V. K. Berglyd, Bernardini, M., Biskup, B., Boccardi, A., Bogey, T., Bohl, T., Bracco, C., Braunmüller, F., Burger, S., Burt, G., Bustamante, S., Buttenschön, B., Caldwell, A., Cascella, M., Chappell, J., Chevallay, E., Chung, M., Cooke, D., Damerau, H., Deacon, L., Deubner, L. H., Dexter, A., Doebert, S., Farmer, J., Fedosseev, V. N., Fior, G., Fiorito, R., Fonseca, R. A., Friebel, F., Garolfi, L., Gessner, S., Gorgisyan, I., Gorn, A. A., Granados, E., Grulke, O., Gschwendtner, E., Guerrero, A., Hansen, J., Helm, A., Henderson, J. R., Hessler, C., Hoe, W., Hüther, M., Ibison, M., Jensen, L., Jolly, S., Keeble, F., Kim, S. -Y., Kraus, F., Lefevre, T., LeGodec, G., Li, Y., Liu, S., Lopes, N., Lotov, K. V., Brun, L. Maricalva, Martyanov, M., Mazzoni, S., Godoy, D. Medina, Minakov, V. A., Mitchell, J., Molendijk, J. C., Mompo, R., Moody, J. T., Moreira, M., Muggli, P., Mutin, C., Öz, E., Ozturk, E., Pasquino, C., Pardons, A., Asmus, F. Pena, Pepitone, K., Perera, A., Petrenko, A., Pitman, S., Plyushchev, G., Pukhov, A., Rey, S., Rieger, K., Ruhl, H., Schmidt, J. S., Shalimova, I. A., Shaposhnikova, E., Sherwood, P., Silva, L. O., Soby, L., Sosedkin, A. P., Speroni, R., Spitsyn, R. I., Tuev, P. V., Turner, M., Velotti, F., Verra, L., Verzilov, V. A., Vieira, J., Vincke, H., Welsch, C. P., Williamson, B., Wing, M., Woolley, B., and Xia, G.
Subjects: Physics - Accelerator Physics, Physics - Plasma Physics
Abstract: We give direct experimental evidence for the observation of the full transverse self-modulation of a relativistic proton bunch propagating through a dense plasma. The bunch exits the plasma with a density modulation resulting from radial wakefield effects with a period reciprocal to the plasma frequency. We show that the modulation is seeded by using an intense laser pulse co-propagating with the proton bunch which creates a relativistic ionization front within the bunch. We show by varying the plasma density over one order of magnitude that the modulation period scales with the expected dependence on the plasma density., Comment: 4 figures, AWAKE collaboration paper, Submitted to PRL
Published: 2018
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6. Acceleration of electrons in the plasma wakefield of a proton bunch

Author: The AWAKE Collaboration, Adli, E., Ahuja, A., Apsimon, O., Apsimon, R., Bachmann, A. -M., Barrientos, D., Batsch, F., Bauche, J., Olsen, V. K. Berglyd, Bernardini, M., Bohl, T., Bracco, C., Braunmueller, F., Burt, G., Buttenschoen, B., Caldwell, A., Cascella, M., Chappell, J., Chevallay, E., Chung, M., Cooke, D., Damerau, H., Deacon, L., Deubner, L. H., Dexter, A., Doebert, S., Farmer, J., Fedosseev, V. N., Fiorito, R., Fonseca, R. A., Friebel, F., Garolfi, L., Gessner, S., Gorgisyan, I., Gorn, A. A., Granados, E., Grulke, O., Gschwendtner, E., Hansen, J., Helm, A., Henderson, J. R., Huether, M., Ibison, M., Jensen, L., Jolly, S., Keeble, F., Kim, S. -Y., Kraus, F., Li, Y., Liu, S., Lopes, N., Lotov, K. V., Brun, L. Maricalva, Martyanov, M., Mazzoni, S., Godoy, D. Medina, Minakov, V. A., Mitchell, J., Molendijk, J. C., Moody, J. T., Moreira, M., Muggli, P., Oez, E., Pasquino, C., Pardons, A., Asmus, F. Pena, Pepitone, K., Perera, A., Petrenko, A., Pitman, S., Pukhov, A., Rey, S., Rieger, K., Ruhl, H., Schmidt, J. S., Shalimova, I. A., Sherwood, P., Silva, L. O., Soby, L., Sosedkin, A. P., Speroni, R., Spitsyn, R. I., Tuev, P. V., Turner, M., Velotti, F., Verra, L., Verzilov, V. A., Vieira, J., Welsch, C. P., Williamson, B., Wing, M., Woolley, B., and Xia, G.
Subjects: Physics - Accelerator Physics, High Energy Physics - Experiment, Physics - Plasma Physics
Abstract: High energy particle accelerators have been crucial in providing a deeper understanding of fundamental particles and the forces that govern their interactions. In order to increase the energy or reduce the size of the accelerator, new acceleration schemes need to be developed. Plasma wakefield acceleration, in which the electrons in a plasma are excited, leading to strong electric fields, is one such promising novel acceleration technique. Pioneering experiments have shown that an intense laser pulse or electron bunch traversing a plasma, drives electric fields of 10s GV/m and above. These values are well beyond those achieved in conventional RF accelerators which are limited to ~0.1 GV/m. A limitation of laser pulses and electron bunches is their low stored energy, which motivates the use of multiple stages to reach very high energies. The use of proton bunches is compelling, as they have the potential to drive wakefields and accelerate electrons to high energy in a single accelerating stage. The long proton bunches currently available can be used, as they undergo self-modulation, a particle-plasma interaction which longitudinally splits the bunch into a series of high density microbunches, which then act resonantly to create large wakefields. The AWAKE experiment at CERN uses intense bunches of protons, each of energy 400 GeV, with a total bunch energy of 19 kJ, to drive a wakefield in a 10 m long plasma. Bunches of electrons are injected into the wakefield formed by the proton microbunches. This paper presents measurements of electrons accelerated up to 2 GeV at AWAKE. This constitutes the first demonstration of proton-driven plasma wakefield acceleration. The potential for this scheme to produce very high energy electron bunches in a single accelerating stage means that the results shown here are a significant step towards the development of future high energy particle accelerators., Comment: 7 pages, 4 figures. Updated acknowledgements and one reference
Published: 2018
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7. Proton-driven plasma wakefield acceleration in AWAKE.

Author: Gschwendtner, E, Turner, M, Adli, E, Ahuja, A, Apsimon, O, Apsimon, R, Bachmann, A-M, Batsch, F, Bracco, C, Braunmüller, F, Burger, S, Burt, G, Buttenschön, B, Caldwell, A, Chappell, J, Chevallay, E, Chung, M, Cooke, D, Damerau, H, Deubner, LH, Dexter, A, Doebert, S, Farmer, J, Fedosseev, VN, Fiorito, R, Fonseca, RA, Friebel, F, Garolfi, L, Gessner, S, Goddard, B, Gorgisyan, I, Gorn, AA, Granados, E, Grulke, O, Hartin, A, Helm, A, Henderson, JR, Hüther, M, Ibison, M, Jolly, S, Keeble, F, Kelisani, MD, Kim, S-Y, Kraus, F, Krupa, M, Lefevre, T, Li, Y, Liu, S, Lopes, N, Lotov, KV, Martyanov, M, Mazzoni, S, Minakov, VA, Molendijk, JC, Moody, JT, Moreira, M, Muggli, P, Panuganti, H, Pardons, A, Peña Asmus, F, Perera, A, Petrenko, A, Pukhov, A, Rey, S, Sherwood, P, Silva, LO, Sosedkin, AP, Tuev, PV, Velotti, F, Verra, L, Verzilov, VA, Vieira, J, Welsch, CP, Wendt, M, Williamson, B, Wing, M, Woolley, B, and Xia, G
Subjects: Nuclear and Plasma Physics, Synchrotrons and Accelerators, Physical Sciences, AWAKE, plasma wakefield acceleration, seeded self modulation, AWAKE Collaboration, physics.acc-ph, General Science & Technology
Abstract: In this article, we briefly summarize the experiments performed during the first run of the Advanced Wakefield Experiment, AWAKE, at CERN (European Organization for Nuclear Research). The final goal of AWAKE Run 1 (2013-2018) was to demonstrate that 10-20 MeV electrons can be accelerated to GeV energies in a plasma wakefield driven by a highly relativistic self-modulated proton bunch. We describe the experiment, outline the measurement concept and present first results. Last, we outline our plans for the future. This article is part of the Theo Murphy meeting issue 'Directions in particle beam-driven plasma wakefield acceleration'.
Published: 2019

8. AWAKE readiness for the study of the seeded self-modulation of a 400\,GeV proton bunch

Author: Muggli, P., Adli, E., Apsimon, R., Asmus, F., Baartman, R., Bachmann, A. -M., Marin, M. Barros, Batsch, F., Bauche, J., Olsen, V. K. Berglyd, Bernardini, M., Biskup, B., Boccardi, A., Bogey, T., Bohl, T., Bracco, C., Braunmuller, F., Burger, S., Burt, G., Bustamante, S., Buttenschon, B., Butterworth, A., Caldwell, A., Cascella, M., Chevallay, E., Chung, M., Damerau, H., Deacon, L., Dexter, A., Dirksen, P., Doebert, S., Farmer, J., Fedosseev, V., Feniet, T., Fior, G., Fiorito, R., Fonseca, R., Friebel, F., Gander, P., Gessner, S., Gorgisyan, I., Gorn, A. A., Grulke, O., Gschwendtner, E., Guerrero, A., Hansen, J., Hessler, C., Hofle, W., Holloway, J., Huther, M., Ibison, M., Islam, M. R., Jensen, L., Jolly, S., Kasim, M., Keeble, F., Kim, S. -Y., Krause, F., Lasheen, A., Lefevre, T., LeGodec, G., Li, Y., Liu, S., Lopes, N., Lotov, K. V., Martyanov, M., Mazzoni, S., Godoy, D. Medina, Mete, O., Minakov, V. A., Mompo, R., Moody, J., Moreira, M. T., Mitchell, J., Mutin, C., Norreys, P., Oz, E., Ozturk, E., Pauw, W., Pardone, A., Pasquino, C., Pepitone, K., Petrenko, A., Pitmann, S., Plyushchev, G., Pukhov, A., Rieger, K., Ruhl, H., Schmidt, J., Shalimova, I. A., Shaposhnikova, E., Sherwood, P., Silva, L., Sosedkin, A. P., Spitsyn, R. I., Szczurek, K., Thomas, J., Tuev, P. V., Turner, M., Verzilov, V., Vieira, J., Vincke, H., Welsch, C. P., Williamson, B., Wing, M., Xia, G., and Zhang, H.
Subjects: Physics - Plasma Physics, Physics - Accelerator Physics
Abstract: AWAKE is a proton-driven plasma wakefield acceleration experiment. % We show that the experimental setup briefly described here is ready for systematic study of the seeded self-modulation of the 400\,GeV proton bunch in the 10\,m-long rubidium plasma with density adjustable from 1 to 10$\times10^{14}$\,cm$^{-3}$. % We show that the short laser pulse used for ionization of the rubidium vapor propagates all the way along the column, suggesting full ionization of the vapor. % We show that ionization occurs along the proton bunch, at the laser time and that the plasma that follows affects the proton bunch. %, Comment: Presented as an invited talk at the EPS=Plasma Physics Conference 2017
Published: 2017
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9. PERLE: Powerful Energy Recovery Linac for Experiments - Conceptual Design Report

Author: Angal-Kalinin, D., Arduini, G., Auchmann, B., Bernauer, J., Bogacz, A., Bordry, F., Bousson, S., Bracco, C., Brüning, O., Calaga, R., Cassou, K., Chetvertkova, V., Cormier, E., Daly, E., Douglas, D., Dupraz, K., Goddard, B., Henry, J., Hutton, A., Jensen, E., Kaabi, W., Klein, M., Kostka, P., Marhauser, F., Martens, A., Milanese, A., Militsyn, B., Peinaud, Y., Pellegrini, D., Pietralla, N., Pupkov, Y. A., Rimmer, R. A., Schirm, K., Schulte, D., Smith, S., Stocchi, A., Valloni, A., Welsch, C., Willering, G., Wollmann, D., Zimmermann, F., and Zomer, F.
Subjects: Physics - Accelerator Physics
Abstract: A conceptual design is presented of a novel ERL facility for the development and application of the energy recovery technique to linear electron accelerators in the multi-turn, large current and large energy regime. The main characteristics of the powerful energy recovery linac experiment facility (PERLE) are derived from the design of the Large Hadron electron Collider, an electron beam upgrade under study for the LHC, for which it would be the key demonstrator. PERLE is thus projected as a facility to investigate efficient, high current (> 10 mA) ERL operation with three re-circulation passages through newly designed SCRF cavities, at 801.58 MHz frequency, and following deceleration over another three re-circulations. In its fully equipped configuration, PERLE provides an electron beam of approximately 1 GeV energy. A physics programme possibly associated with PERLE is sketched, consisting of high precision elastic electron-proton scattering experiments, as well as photo-nuclear reactions of unprecedented intensities with up to 30 MeV photon beam energy as may be obtained using Fabry-Perot cavities. The facility has further applications as a general technology test bed that can investigate and validate novel superconducting magnets (beam induced quench tests) and superconducting RF structures (structure tests with high current beams, beam loading and transients). Besides a chapter on operation aspects, the report contains detailed considerations on the choices for the SCRF structure, optics and lattice design, solutions for arc magnets, source and injector and on further essential components. A suitable configuration derived from the here presented design concept may next be moved forward to a technical design and possibly be built by an international collaboration which is being established., Comment: 112 pages, 63 figures
Published: 2017
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10. Acceleration of electrons in the plasma wakefield of a proton bunch

Author: Adli, E, Ahuja, A, Apsimon, O, Apsimon, R, Bachmann, A-M, Barrientos, D, Batsch, F, Bauche, J, Berglyd Olsen, VK, Bernardini, M, Bohl, T, Bracco, C, Braunmüller, F, Burt, G, Buttenschön, B, Caldwell, A, Cascella, M, Chappell, J, Chevallay, E, Chung, M, Cooke, D, Damerau, H, Deacon, L, Deubner, LH, Dexter, A, Doebert, S, Farmer, J, Fedosseev, VN, Fiorito, R, Fonseca, RA, Friebel, F, Garolfi, L, Gessner, S, Gorgisyan, I, Gorn, AA, Granados, E, Grulke, O, Gschwendtner, E, Hansen, J, Helm, A, Henderson, JR, Hüther, M, Ibison, M, Jensen, L, Jolly, S, Keeble, F, Kim, S-Y, Kraus, F, Li, Y, Liu, S, Lopes, N, Lotov, KV, Maricalva Brun, L, Martyanov, M, Mazzoni, S, Medina Godoy, D, Minakov, VA, Mitchell, J, Molendijk, JC, Moody, JT, Moreira, M, Muggli, P, Öz, E, Pasquino, C, Pardons, A, Peña Asmus, F, Pepitone, K, Perera, A, Petrenko, A, Pitman, S, Pukhov, A, Rey, S, Rieger, K, Ruhl, H, Schmidt, JS, Shalimova, IA, Sherwood, P, Silva, LO, Soby, L, Sosedkin, AP, Speroni, R, Spitsyn, RI, Tuev, PV, Turner, M, Velotti, F, Verra, L, Verzilov, VA, Vieira, J, Welsch, CP, Williamson, B, Wing, M, Woolley, B, and Xia, G
Subjects: Nuclear and Plasma Physics, Physical Sciences, Affordable and Clean Energy, General Science & Technology
Abstract: High-energy particle accelerators have been crucial in providing a deeper understanding of fundamental particles and the forces that govern their interactions. To increase the energy of the particles or to reduce the size of the accelerator, new acceleration schemes need to be developed. Plasma wakefield acceleration1-5, in which the electrons in a plasma are excited, leading to strong electric fields (so called 'wakefields'), is one such promising acceleration technique. Experiments have shown that an intense laser pulse6-9 or electron bunch10,11 traversing a plasma can drive electric fields of tens of gigavolts per metre and above-well beyond those achieved in conventional radio-frequency accelerators (about 0.1 gigavolt per metre). However, the low stored energy of laser pulses and electron bunches means that multiple acceleration stages are needed to reach very high particle energies5,12. The use of proton bunches is compelling because they have the potential to drive wakefields and to accelerate electrons to high energy in a single acceleration stage13. Long, thin proton bunches can be used because they undergo a process called self-modulation14-16, a particle-plasma interaction that splits the bunch longitudinally into a series of high-density microbunches, which then act resonantly to create large wakefields. The Advanced Wakefield (AWAKE) experiment at CERN17-19 uses high-intensity proton bunches-in which each proton has an energy of 400 gigaelectronvolts, resulting in a total bunch energy of 19 kilojoules-to drive a wakefield in a ten-metre-long plasma. Electron bunches are then injected into this wakefield. Here we present measurements of electrons accelerated up to two gigaelectronvolts at the AWAKE experiment, in a demonstration of proton-driven plasma wakefield acceleration. Measurements were conducted under various plasma conditions and the acceleration was found to be consistent and reliable. The potential for this scheme to produce very high-energy electron bunches in a single accelerating stage20 means that our results are an important step towards the development of future high-energy particle accelerators21,22.
Published: 2018

11. LHC Upgrades in preparation of Run 3

Author: Arduini, G., primary, Baglin, V., additional, Bartosik, H., additional, Bottura, L., additional, Bracco, C., additional, Bradu, B., additional, Bregliozzi, G., additional, Brodzinski, K., additional, Bruce, R., additional, Calviani, M., additional, Chiggiato, P., additional, Cruikshank, P., additional, Claudet, S., additional, Delikaris, D., additional, Fartoukh, S., additional, Garion, C., additional, Himmerlich, M., additional, Hostettler, M., additional, Iadarola, G., additional, Kostoglou, S., additional, Le Naour, S., additional, Lechner, A., additional, Lefevre, T., additional, Mether, L., additional, Papaphilippou, Y., additional, Petit, V., additional, Pojer, M., additional, Poyet, A., additional, Redaelli, S., additional, Rodriguez Mateos, F., additional, Rumolo, G., additional, Salvant, B., additional, Sanchez Galan, F., additional, Siemko, A., additional, Solfaroli-Camillocci, M., additional, Sterbini, G., additional, Taborelli, M., additional, Tavian, L., additional, Timko, H., additional, Tock, J.-Ph., additional, Verweij, A., additional, Wendt, M., additional, Wenninger, J., additional, Wollmann, D., additional, and Yin Vallgren, Ch., additional
Published: 2024
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12. Correction to ‘Proton-driven plasma wakefield acceleration in AWAKE’

Author: The AWAKE Collaboration, Gschwendtner, E., Turner, M., Adli, E., Ahuja, A., Apsimon, O., Apsimon, R., Bachmann, A.-M., Batsch, F., Bracco, C., Braunmüller, F., Burger, S., Burt, G., Buttenschön, B., Caldwell, A., Chappell, J., Chevallay, E., Chung, M., Cooke, D., Damerau, H., Deubner, L. H., Dexter, A., Doebert, S., Farmer, J., Fedosseev, V. N., Fiorito, R., Fonseca, R. A., Friebel, F., Garolfi, L., Gessner, S., Goddard, B., Gorgisyan, I., Gorn, A. A., Granados, E., Grulke, O., Hartin, A., Helm, A., Henderson, J. R., Hüther, M., Ibison, M., Jolly, S., Keeble, F., Kelisani, M. D., Kim, S.-Y., Kraus, F., Krupa, M., Lefevre, T., Li, Y., Liu, S., Lopes, N., Lotov, K. V., Martyanov, M., Mazzoni, S., Minakov, V. A., Molendijk, J. C., Moody, J. T., Moreira, M., Muggli, P., Panuganti, H., Pardons, A., Asmus, F. Peña, Perera, A., Petrenko, A., Pukhov, A., Rey, S., Sherwood, P., Silva, L. O., Sosedkin, A. P., Tuev, P. V., Velotti, F., Verra, L., Verzilov, V. A., Vieira, J., Welsch, C. P., Wendt, M., Williamson, B., Wing, M., Woolley, B., and Xia, G.
Published: 2020

13. AWAKE, The Advanced Proton Driven Plasma Wakefield Acceleration Experiment at CERN

Author: Gschwendtner, E., Adli, E., Amorim, L., Apsimon, R., Assmann, R., Bachmann, A. -M., Batsch, F., Bauche, J., Olsen, V. K. Berglyd, Bernardini, M., Bingham, R., Biskup, B., Bohl, T., Bracco, C., Burrows, P. N., Burt, G., Buttenschon, B., Butterworth, A., Caldwell, A., Cascella, M., Chevallay, E., Cipiccia, S., Damerau, H., Deacon, L., Dirksen, P., Doebert, S., Dorda, U., Farmer, J., Fedosseev, V., Feldbaumer, E., Fiorito, R., Fonseca, R., Friebel, F., Gorn, A. A., Grulke, O., Hansen, J., Hessler, C., Hofle, W., Holloway, J., Huther, M., Jaroszynski, D., Jensen, L., Jolly, S., Joulaei, A., Kasim, M., Keeble, F., Li, Y., Liu, S., Lopes, N., Lotov, K. V., Mandry, S., Martorelli, R., Martyanov, M., Mazzoni, S., Mete, O., Minakov, V. A., Mitchell, J., Moody, J., Muggli, P., Najmudin, Z., Norreys, P., Oz, E., Pardons, A., Pepitone, K., Petrenko, A., Plyushchev, G., Pukhov, A., Rieger, K., Ruhl, H., Salveter, F., Savard, N., Schmidt, J., Seryi, A., Shaposhnikova, E., Sheng, Z. M., Sherwood, P., Silva, L., Soby, L., Sosedkin, A. P., Spitsyn, R. I., Trines, R., Tuev, P. V., Turner, M., Verzilov, V., Vieira, J., Vincke, H., Wei, Y., Welsch, C. P., Wing, M., Xia, G., and Zhang, H.
Subjects: Physics - Accelerator Physics, Physics - Plasma Physics
Abstract: The Advanced Proton Driven Plasma Wakefield Acceleration Experiment (AWAKE) aims at studying plasma wakefield generation and electron acceleration driven by proton bunches. It is a proof-of-principle R&D experiment at CERN and the world's first proton driven plasma wakefield acceleration experiment. The AWAKE experiment will be installed in the former CNGS facility and uses the 400 GeV/c proton beam bunches from the SPS. The first experiments will focus on the self-modulation instability of the long (rms ~12 cm) proton bunch in the plasma. These experiments are planned for the end of 2016. Later, in 2017/2018, low energy (~15 MeV) electrons will be externally injected to sample the wakefields and be accelerated beyond 1 GeV. The main goals of the experiment will be summarized. A summary of the AWAKE design and construction status will be presented., Comment: 7 pages, 7 figures, 2 tables
Published: 2015
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14. The Large Hadron–Electron Collider at the HL-LHC

Author: Agostini, P, Aksakal, H, Alekhin, S, Allport, P P, Andari, N, Andre, K D J, Angal-Kalinin, D, Antusch, S, Aperio Bella, L, Apolinario, L, Apsimon, R, Apyan, A, Arduini, G, Ari, V, Armbruster, A, Armesto, N, Auchmann, B, Aulenbacher, K, Azuelos, G, Backovic, S, Bailey, I, Bailey, S, Balli, F, Behera, S, Behnke, O, Ben-Zvi, I, Benedikt, M, Bernauer, J, Bertolucci, S, Biswal, S S, Blümlein, J, Bogacz, A, Bonvini, M, Boonekamp, M, Bordry, F, Boroun, G R, Bottura, L, Bousson, S, Bouzas, A O, Bracco, C, Bracinik, J, Britzger, D, Brodsky, S J, Bruni, C, Brüning, O, Burkhardt, H, Cakir, O, Calaga, R, Caldwell, A, Calıskan, A, Camarda, S, Catalan-Lasheras, N C, Cassou, K, Cepila, J, Cetinkaya, V, Chetvertkova, V, Cole, B, Coleppa, B, Cooper-Sarkar, A, Cormier, E, Cornell, A S, Corsini, R, Cruz-Alaniz, E, Currie, J, Curtin, D, D’Onofrio, M, Dainton, J, Daly, E, Das, A, Das, S P, Dassa, L, de Blas, J, Delle Rose, L, Denizli, H, Deshpande, K S, Douglas, D, Duarte, L, Dupraz, K, Dutta, S, Efremov, A V, Eichhorn, R, Eskola, K J, Ferreiro, E G, Fischer, O, Flores-Sánchez, O, Forte, S, Gaddi, A, Gao, J, Gehrmann, T, Gehrmann-De Ridder, A, Gerigk, F, Gilbert, A, Giuli, F, Glazov, A, Glover, N, Godbole, R M, Goddard, B, Gonçalves, V, Gonzalez-Sprinberg, G A, Goyal, A, Grames, J, Granados, E, Grassellino, A, Gunaydin, Y O, Guo, Y C, Guzey, V, Gwenlan, C, Hammad, A, Han, C C, Harland-Lang, L, Haug, F, Hautmann, F, Hayden, D, Hessler, J, Helenius, I, Henry, J, Hernandez-Sanchez, J, Hesari, H, Hobbs, T J, Hod, N, Hoffstaetter, G H, Holzer, B, Honorato, C G, Hounsell, B, Hu, N, Hug, F, Huss, A, Hutton, A, Islam, R, Iwamoto, S, Jana, S, Jansova, M, Jensen, E, Jones, T, Jowett, J M, Kaabi, W, Kado, M, Kalinin, D A, Karadeniz, H, Kawaguchi, S, Kaya, U, Khalek, R A, Khanpour, H, Kilic, A, Klein, M, Klein, U, Kluth, S, Köksal, M, Kocak, F, Korostelev, M, Kostka, P, Krelina, M, Kretzschmar, J, Kuday, S, Kulipanov, G, Kumar, M, Kuze, M, Lappi, T, Larios, F, Latina, A, Laycock, P, Lei, G, Levitchev, E, Levonian, S, Levy, A, Li, R, Li, X, Liang, H, Litvinenko, V, Liu, M, Liu, T, Liu, W, Liu, Y, Liuti, S, Lobodzinska, E, Longuevergne, D, Luo, X, Ma, W, Machado, M, Mandal, S, Mäntysaari, H, Marhauser, F, Marquet, C, Martens, A, Martin, R, Marzani, S, McFayden, J, Mcintosh, P, Mellado, B, Meot, F, Milanese, A, Milhano, J G, Militsyn, B, Mitra, M, Moch, S, Mohammadi Najafabadi, M, Mondal, S, Moretti, S, Morgan, T, Morreale, A, Nadolsky, P, Navarra, F, Nergiz, Z, Newman, P, Niehues, J, Nissen, E A, Nowakowski, M, Okada, N, Olivier, G, Olness, F, Olry, G, Osborne, J A, Ozansoy, A, Pan, R, Parker, B, Patra, M, Paukkunen, H, Peinaud, Y, Pellegrini, D, Perez-Segurana, G, Perini, D, Perrot, L, Pietralla, N, Pilicer, E, Pire, B, Pires, J, Placakyte, R, Poelker, M, Polifka, R, Polini, A, Poulose, P, Pownall, G, Pupkov, Y A, Queiroz, F S, Rabbertz, K, Radescu, V, Rahaman, R, Rai, S K, Raicevic, N, Ratoff, P, Rashed, A, Raut, D, Raychaudhuri, S, Repond, J, Rezaeian, A H, Rimmer, R, Rinolfi, L, Rojo, J, Rosado, A, Ruan, X, Russenschuck, S, Sahin, M, Salgado, C A, Sampayo, O A, Satendra, K, Satyanarayan, N, Schenke, B, Schirm, K, Schopper, H, Schott, M, Schulte, D, Schwanenberger, C, Sekine, T, Senol, A, Seryi, A, Setiniyaz, S, Shang, L, Shen, X, Shipman, N, Sinha, N, Slominski, W, Smith, S, Solans, C, Song, M, Spiesberger, H, Stanyard, J, Starostenko, A, Stasto, A, Stocchi, A, Strikman, M, Stuart, M J, Sultansoy, S, Sun, H, Sutton, M, Szymanowski, L, Tapan, I, Tapia-Takaki, D, Tanaka, M, Tang, Y, Tasci, A T, Ten-Kate, A T, Thonet, P, Tomas-Garcia, R, Tommasini, D, Trbojevic, D, Trott, M, Tsurin, I, Tudora, A, Turk Cakir, I, Tywoniuk, K, Vallerand, C, Valloni, A, Verney, D, Vilella, E, Walker, D, Wallon, S, Wang, B, Wang, K, Wang, X, Wang, Z S, Wei, H, Welsch, C, Willering, G, Williams, P H, Wollmann, D, Xiaohao, C, Xu, T, Yaguna, C E, Yamaguchi, Y, Yamazaki, Y, Yang, H, Yilmaz, A, Yock, P, Yue, C X, Zadeh, S G, Zenaiev, O, Zhang, C, Zhang, J, Zhang, R, Zhang, Z, Zhu, G, Zhu, S, Zimmermann, F, Zomer, F, Zurita, J, Zurita, P, Agostini, P, Aksakal, H, Alekhin, S, Allport, P P, Andari, N, Andre, K D J, Angal-Kalinin, D, Antusch, S, Aperio Bella, L, Apolinario, L, Apsimon, R, Apyan, A, Arduini, G, Ari, V, Armbruster, A, Armesto, N, Auchmann, B, Aulenbacher, K, Azuelos, G, Backovic, S, Bailey, I, Bailey, S, Balli, F, Behera, S, Behnke, O, Ben-Zvi, I, Benedikt, M, Bernauer, J, Bertolucci, S, Biswal, S S, Blümlein, J, Bogacz, A, Bonvini, M, Boonekamp, M, Bordry, F, Boroun, G R, Bottura, L, Bousson, S, Bouzas, A O, Bracco, C, Bracinik, J, Britzger, D, Brodsky, S J, Bruni, C, Brüning, O, Burkhardt, H, Cakir, O, Calaga, R, Caldwell, A, Calıskan, A, Camarda, S, Catalan-Lasheras, N C, Cassou, K, Cepila, J, Cetinkaya, V, Chetvertkova, V, Cole, B, Coleppa, B, Cooper-Sarkar, A, Cormier, E, Cornell, A S, Corsini, R, Cruz-Alaniz, E, Currie, J, Curtin, D, D’Onofrio, M, Dainton, J, Daly, E, Das, A, Das, S P, Dassa, L, de Blas, J, Delle Rose, L, Denizli, H, Deshpande, K S, Douglas, D, Duarte, L, Dupraz, K, Dutta, S, Efremov, A V, Eichhorn, R, Eskola, K J, Ferreiro, E G, Fischer, O, Flores-Sánchez, O, Forte, S, Gaddi, A, Gao, J, Gehrmann, T, Gehrmann-De Ridder, A, Gerigk, F, Gilbert, A, Giuli, F, Glazov, A, Glover, N, Godbole, R M, Goddard, B, Gonçalves, V, Gonzalez-Sprinberg, G A, Goyal, A, Grames, J, Granados, E, Grassellino, A, Gunaydin, Y O, Guo, Y C, Guzey, V, Gwenlan, C, Hammad, A, Han, C C, Harland-Lang, L, Haug, F, Hautmann, F, Hayden, D, Hessler, J, Helenius, I, Henry, J, Hernandez-Sanchez, J, Hesari, H, Hobbs, T J, Hod, N, Hoffstaetter, G H, Holzer, B, Honorato, C G, Hounsell, B, Hu, N, Hug, F, Huss, A, Hutton, A, Islam, R, Iwamoto, S, Jana, S, Jansova, M, Jensen, E, Jones, T, Jowett, J M, Kaabi, W, Kado, M, Kalinin, D A, Karadeniz, H, Kawaguchi, S, Kaya, U, Khalek, R A, Khanpour, H, Kilic, A, Klein, M, Klein, U, Kluth, S, Köksal, M, Kocak, F, Korostelev, M, Kostka, P, Krelina, M, Kretzschmar, J, Kuday, S, Kulipanov, G, Kumar, M, Kuze, M, Lappi, T, Larios, F, Latina, A, Laycock, P, Lei, G, Levitchev, E, Levonian, S, Levy, A, Li, R, Li, X, Liang, H, Litvinenko, V, Liu, M, Liu, T, Liu, W, Liu, Y, Liuti, S, Lobodzinska, E, Longuevergne, D, Luo, X, Ma, W, Machado, M, Mandal, S, Mäntysaari, H, Marhauser, F, Marquet, C, Martens, A, Martin, R, Marzani, S, McFayden, J, Mcintosh, P, Mellado, B, Meot, F, Milanese, A, Milhano, J G, Militsyn, B, Mitra, M, Moch, S, Mohammadi Najafabadi, M, Mondal, S, Moretti, S, Morgan, T, Morreale, A, Nadolsky, P, Navarra, F, Nergiz, Z, Newman, P, Niehues, J, Nissen, E A, Nowakowski, M, Okada, N, Olivier, G, Olness, F, Olry, G, Osborne, J A, Ozansoy, A, Pan, R, Parker, B, Patra, M, Paukkunen, H, Peinaud, Y, Pellegrini, D, Perez-Segurana, G, Perini, D, Perrot, L, Pietralla, N, Pilicer, E, Pire, B, Pires, J, Placakyte, R, Poelker, M, Polifka, R, Polini, A, Poulose, P, Pownall, G, Pupkov, Y A, Queiroz, F S, Rabbertz, K, Radescu, V, Rahaman, R, Rai, S K, Raicevic, N, Ratoff, P, Rashed, A, Raut, D, Raychaudhuri, S, Repond, J, Rezaeian, A H, Rimmer, R, Rinolfi, L, Rojo, J, Rosado, A, Ruan, X, Russenschuck, S, Sahin, M, Salgado, C A, Sampayo, O A, Satendra, K, Satyanarayan, N, Schenke, B, Schirm, K, Schopper, H, Schott, M, Schulte, D, Schwanenberger, C, Sekine, T, Senol, A, Seryi, A, Setiniyaz, S, Shang, L, Shen, X, Shipman, N, Sinha, N, Slominski, W, Smith, S, Solans, C, Song, M, Spiesberger, H, Stanyard, J, Starostenko, A, Stasto, A, Stocchi, A, Strikman, M, Stuart, M J, Sultansoy, S, Sun, H, Sutton, M, Szymanowski, L, Tapan, I, Tapia-Takaki, D, Tanaka, M, Tang, Y, Tasci, A T, Ten-Kate, A T, Thonet, P, Tomas-Garcia, R, Tommasini, D, Trbojevic, D, Trott, M, Tsurin, I, Tudora, A, Turk Cakir, I, Tywoniuk, K, Vallerand, C, Valloni, A, Verney, D, Vilella, E, Walker, D, Wallon, S, Wang, B, Wang, K, Wang, X, Wang, Z S, Wei, H, Welsch, C, Willering, G, Williams, P H, Wollmann, D, Xiaohao, C, Xu, T, Yaguna, C E, Yamaguchi, Y, Yamazaki, Y, Yang, H, Yilmaz, A, Yock, P, Yue, C X, Zadeh, S G, Zenaiev, O, Zhang, C, Zhang, J, Zhang, R, Zhang, Z, Zhu, G, Zhu, S, Zimmermann, F, Zomer, F, Zurita, J, and Zurita, P
Abstract: The Large Hadron–Electron Collider (LHeC) is designed to move the field of deep inelastic scattering (DIS) to the energy and intensity frontier of particle physics. Exploiting energy-recovery technology, it collides a novel, intense electron beam with a proton or ion beam from the High-Luminosity Large Hadron Collider (HL-LHC). The accelerator and interaction region are designed for concurrent electron–proton and proton–proton operations. This report represents an update to the LHeC’s conceptual design report (CDR), published in 2012. It comprises new results on the parton structure of the proton and heavier nuclei, QCD dynamics, and electroweak and top-quark physics. It is shown how the LHeC will open a new chapter of nuclear particle physics by extending the accessible kinematic range of lepton–nucleus scattering by several orders of magnitude. Due to its enhanced luminosity and large energy and the cleanliness of the final hadronic states, the LHeC has a strong Higgs physics programme and its own discovery potential for new physics. Building on the 2012 CDR, this report contains a detailed updated design for the energy-recovery electron linac (ERL), including a new lattice, magnet and superconducting radio-frequency technology, and further components. Challenges of energy recovery are described, and the lower-energy, high-current, three-turn ERL facility, PERLE at Orsay, is presented, which uses the LHeC characteristics serving as a development facility for the design and operation of the LHeC. An updated detector design is presented corresponding to the acceptance, resolution, and calibration goals that arise from the Higgs and parton-density-function physics programmes. This paper also presents novel results for the Future Circular Collider in electron–hadron (FCC-eh) mode, which utilises the same ERL technology to further extend the reach of DIS to even higher centre-of-mass energies.
Published: 2024

15. PERLE. Powerful energy recovery linac for experiments. Conceptual design report

Author: Angal-Kalinin, D., Arduini, G., Auchmann, B., Bernauer, J., Bogacz, A., Bordry, F., Bousson, S., Bracco, C., Brüning, O., Calaga, R., Cassou, K., Chetvertkova, V., Cormier, E., Daly, E., Douglas, D., Dupraz, K., Goddard, B., Henry, J., Hutton, A., Jensen, E., Kaabi, W., Klein, M., Kostka, P., Lasheras, N., Levichev, E., Marhauser, F., Martens, A., Milanese, A., Militsyn, B., Peinaud, Y., Pellegrini, D., Pietralla, N., Pupkov, Y., Rimmer, R., Schirm, K., Schulte, D., Smith, S., Stocchi, A., Valloni, A., Welsch, C., Willering, G., Wollmann, D., Zimmermann, F., Zomer, F., Angal-Kalinin, D., Arduini, G., Auchmann, B., Bernauer, J., Bogacz, A., Bordry, F., Bousson, S., Bracco, C., Brüning, O., Calaga, R., Cassou, K., Chetvertkova, V., Cormier, E., Daly, E., Douglas, D., Dupraz, K., Goddard, B., Henry, J., Hutton, A., Jensen, E., Kaabi, W., Klein, M., Kostka, P., Lasheras, N., Levichev, E., Marhauser, F., Martens, A., Milanese, A., Militsyn, B., Peinaud, Y., Pellegrini, D., Pietralla, N., Pupkov, Y., Rimmer, R., Schirm, K., Schulte, D., Smith, S., Stocchi, A., Valloni, A., Welsch, C., Willering, G., Wollmann, D., Zimmermann, F., and Zomer, F.
Abstract: A conceptual design is presented of a novel energy-recovering linac (ERL) facility for the development and application of the energy recovery technique to linear electron accelerators in the multi-turn, large current and large energy regime. The main characteristics of the powerful energy recovery linac experiment facility (PERLE) are derived from the design of the Large Hadron electron Collider, an electron beam upgrade under study for the LHC, for which it would be the key demonstrator. PERLE is thus projected as a facility to investigate efficient, high current (HC) (>10 mA) ERL operation with three re-circulation passages through newly designed SCRF cavities, at 801.58 MHz frequency, and following deceleration over another three re-circulations. In its fully equipped configuration, PERLE provides an electron beam of approximately 1 GeV energy. A physics programme possibly associated with PERLE is sketched, consisting of high precision elastic electron–proton scattering experiments, as well as photo-nuclear reactions of unprecedented intensities with up to 30 MeV photon beam energy as may be obtained using Fabry–Perot cavities. The facility has further applications as a general technology test bed that can investigate and validate novel superconducting magnets (beam induced quench tests) and superconducting RF structures (structure tests with HC beams, beam loading and transients). Besides a chapter on operation aspects, the report contains detailed considerations on the choices for the SCRF structure, optics and lattice design, solutions for arc magnets, source and injector and on further essential components. A suitable configuration derived from the here presented design concept may next be moved forward to a technical design and possibly be built by an international collaboration which is being established.
Published: 2024

16. Path to AWAKE: Evolution of the concept

Author: Caldwell, A., Adli, E., Amorim, L., Apsimon, R., Argyropoulos, T., Assmann, R., Bachmann, A. -M., Batsch, F., Bauche, J., Olsen, V. K. Berglyd, Bernardini, M., Bingham, R., Biskup, B., Bohl, T., Bracco, C., Burrows, P. N., Burt, G., Buttenschon, B., Butterworth, A., Cascella, M., Chattopadhyay, S., Chevallay, E., Cipiccia, S., Damerau, H., Deacon, L., Dirksen, P., Doebert, S., Dorda, U., Elsen, E., Farmer, J., Fartoukh, S., Fedosseev, V., Feldbaumer, E., Fiorito, R., Fonseca, R., Friebel, F., Geschonke, G., Goddard, B., Gorn, A. A., Grulke, O., Gschwendtner, E., Hansen, J., Hessler, C., Hillenbrand, S., Hofle, W., Holloway, J., Huang, C., Huther, M., Jaroszynski, D., Jensen, L., Jolly, S., Joulaei, A., Kasim, M., Keeble, F., Kersevan, R., Kumar, N., Li, Y., Liu, S., Lopes, N., Lotov, K. V., Lu, W., Machacek, J., Mandry, S., Martin, I., Martorelli, R., Martyanov, M., Mazzoni, S., Meddahi, M., Merminga, L., Mete, O., Minakov, V. A., Mitchell, J., Moody, J., Muller, A. -S., Najmudin, Z., Noakes, T. C. Q., Norreys, P., Osterhoff, J., Oz, E., Pardons, A., Pepitone, K., Petrenko, A., Plyushchev, G., Pozimski, J., Pukhov, A., Reimann, O., Rieger, K., Roesler, S., Ruhl, H., Rusnak, T., Salveter, F., Savard, N., Schmidt, J., von der Schmitt, H., Seryi, A., Shaposhnikova, E., Sheng, Z. M., Sherwood, P., Silva, L., Simon, F., Soby, L., Sosedkin, A. P., Spitsyn, R. I., Tajima, T., Tarkeshian, R., Timko, H., Trines, R., Tueckmantel, T., Tuev, P. V., Turner, M., Velotti, F., Verzilov, V., Vieira, J., Vincke, H., Wei, Y., Welsch, C. P., Wing, M., Xia, G., Yakimenko, V., Zhang, H., and Zimmermann, F.
Subjects: Physics - Plasma Physics, Physics - Accelerator Physics
Abstract: This report describes the conceptual steps in reaching the design of the AWAKE experiment currently under construction at CERN. We start with an introduction to plasma wakefield acceleration and the motivation for using proton drivers. We then describe the self-modulation instability --- a key to an early realization of the concept. This is then followed by the historical development of the experimental design, where the critical issues that arose and their solutions are described. We conclude with the design of the experiment as it is being realized at CERN and some words on the future outlook. A summary of the AWAKE design and construction status as presented in this conference is given in [1]., Comment: 15 pages, 24 figures, 1 table, 111 references, 121 author from 36 organizations
Published: 2015
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17. Testing Beam-Induced Quench Levels of LHC Superconducting Magnets

Author: Auchmann, B., Baer, T., Bednarek, M., Bellodi, G., Bracco, C., Bruce, R., Cerutti, F., Chetvertkova, V., Dehning, B., Granieri, P. P., Hofle, W., Holzer, E. B., Lechner, A., Del Busto, E. Nebot, Priebe, A., Redaelli, S., Salvachua, B., Sapinski, M., Schmidt, R., Shetty, N., Skordis, E., Solfaroli, M., Steckert, J., Valuch, D., Verweij, A., Wenninger, J., Wollmann, D., and Zerlauth, M.
Subjects: Physics - Accelerator Physics
Abstract: In the years 2009-2013 the Large Hadron Collider (LHC) has been operated with the top beam energies of 3.5 TeV and 4 TeV per proton (from 2012) instead of the nominal 7 TeV. The currents in the superconducting magnets were reduced accordingly. To date only seventeen beam-induced quenches have occurred; eight of them during specially designed quench tests, the others during injection. There has not been a single beam- induced quench during normal collider operation with stored beam. The conditions, however, are expected to become much more challenging after the long LHC shutdown. The magnets will be operating at near nominal currents, and in the presence of high energy and high intensity beams with a stored energy of up to 362 MJ per beam. In this paper we summarize our efforts to understand the quench levels of LHC superconducting magnets. We describe beam-loss events and dedicated experiments with beam, as well as the simulation methods used to reproduce the observable signals. The simulated energy deposition in the coils is compared to the quench levels predicted by electro-thermal models, thus allowing to validate and improve the models which are used to set beam-dump thresholds on beam-loss monitors for Run 2., Comment: 19 pages
Published: 2015
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18. Simulations and measurements of beam loss patterns at the CERN Large Hadron Collider

Author: Bruce, R., Assmann, R. W., Boccone, V., Bracco, C., Brugger, M., Cauchi, M., Cerutti, F., Deboy, D., Ferrari, A., Lari, L., Marsili, A., Mereghetti, A., Mirarchi, D., Quaranta, E., Redaelli, S., Robert-Demolaize, G., Rossi, A., Salvachua, B., Skordis, E., Tambasco, C., Valentino, G., Weiler, T., Vlachoudis, V., and Wollmann, D.
Subjects: Physics - Accelerator Physics, Nuclear Experiment
Abstract: The CERN Large Hadron Collider (LHC) is designed to collide proton beams of unprecedented energy, in order to extend the frontiers of high-energy particle physics. During the first very successful running period in 2010--2013, the LHC was routinely storing protons at 3.5--4 TeV with a total beam energy of up to 146 MJ, and even higher stored energies are foreseen in the future. This puts extraordinary demands on the control of beam losses. An un-controlled loss of even a tiny fraction of the beam could cause a superconducting magnet to undergo a transition into a normal-conducting state, or in the worst case cause material damage. Hence a multi-stage collimation system has been installed in order to safely intercept high-amplitude beam protons before they are lost elsewhere. To guarantee adequate protection from the collimators, a detailed theoretical understanding is needed. This article presents results of numerical simulations of the distribution of beam losses around the LHC that have leaked out of the collimation system. The studies include tracking of protons through the fields of more than 5000 magnets in the 27 km LHC ring over hundreds of revolutions, and Monte-Carlo simulations of particle-matter interactions both in collimators and machine elements being hit by escaping particles. The simulation results agree typically within a factor 2 with measurements of beam loss distributions from the previous LHC run. Considering the complex simulation, which must account for a very large number of unknown imperfections, and in view of the total losses around the ring spanning over 7 orders of magnitude, we consider this an excellent agreement. Our results give confidence in the simulation tools, which are used also for the design of future accelerators.
Published: 2014
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19. Proton-driven plasma wakefield acceleration: a path to the future of high-energy particle physics

Author: AWAKE Collaboration, Assmann, R., Bingham, R., Bohl, T., Bracco, C., Buttenschon, B., Butterworth, A., Caldwell, A., Chattopadhyay, S., Cipiccia, S., Feldbaumer, E., Fonseca, R. A., Goddard, B., Gross, M., Grulke, O., Gschwendtner, E., Holloway, J., Huang, C., Jaroszynski, D., Jolly, S., Kempkes, P., Lopes, N., Lotov, K., Machacek, J., Mandry, S. R., McKenzie, J. W., Meddahi, M., Militsyn, B. L., Moschuering, N., Muggli, P., Najmudin, Z., Noakes, T. C. Q., Norreys, P. A., Oz, E., Pardons, A., Petrenko, A., Pukhov, A., Rieger, K., Reimann, O., Ruhl, H., Shaposhnikova, E., Silva, L. O., Sosedkin, A., Tarkeshian, R., Trines, R. M. G. N., Tuckmantel, T., Vieira, J., Vincke, H., Wing, M., and Xia, G.
Subjects: Physics - Accelerator Physics, High Energy Physics - Experiment, Physics - Plasma Physics
Abstract: New acceleration technology is mandatory for the future elucidation of fundamental particles and their interactions. A promising approach is to exploit the properties of plasmas. Past research has focused on creating large-amplitude plasma waves by injecting an intense laser pulse or an electron bunch into the plasma. However, the maximum energy gain of electrons accelerated in a single plasma stage is limited by the energy of the driver. Proton bunches are the most promising drivers of wakefields to accelerate electrons to the TeV energy scale in a single stage. An experimental program at CERN -- the AWAKE experiment -- has been launched to study in detail the important physical processes and to demonstrate the power of proton-driven plasma wakefield acceleration. Here we review the physical principles and some experimental considerations for a future proton-driven plasma wakefield accelerator., Comment: 12 pages, 5 figures, submitted to Plasma Phys. Control. Fusion special edition for LPAW 2013. Small updates after comments from Journal referees
Published: 2014

20. Proton-driven plasma wakefield acceleration in AWAKE

Author: The AWAKE Collaboration, Gschwendtner, E., Turner, M., Adli, E., Ahuja, A., Apsimon, O., Apsimon, R., Bachmann, A.-M., Batsch, F., Bracco, C., Braunmüller, F., Burger, S., Burt, G., Buttenschön, B., Caldwell, A., Chappell, J., Chevallay, E., Chung, M., Cooke, D., Damerau, H., Deubner, L. H., Dexter, A., Doebert, S., Farmer, J., Fedosseev, V. N., Fiorito, R., Fonseca, R. A., Friebel, F., Garolfi, L., Gessner, S., Goddard, B., Gorgisyan, I., Gorn, A. A., Granados, E., Grulke, O., Hartin, A., Helm, A., Henderson, J. R., Hüther, M., Ibison, M., Jolly, S., Keeble, F., Kelisani, M. D., Kim, S.-Y., Kraus, F., Krupa, M., Lefevre, T., Li, Y., Liu, S., Lopes, N., Lotov, K. V., Martyanov, M., Mazzoni, S., Minakov, V.A., Molendijk, J. C., Moody, J. T., Moreira, M., Muggli, P., Panuganti, H., Pardons, A., Asmus, F. Peña, Perera, A., Petrenko, A., Pukhov, A., Rey, S., Sherwood, P., Silva, L. O., Sosedkin, A. P., Tuev, P. V., Velotti, F., Verra, L., Verzilov, V. A., Vieira, J., Welsch, C. P., Wendt, M., Williamson, B., Wing, M., Woolley, B., and Xia, G.
Published: 2019

21. On the Relation of the LHeC and the LHC

Author: Fernandez, J. L. Abelleira, Adolphsen, C., Adzic, P., Akay, A. N., Aksakal, H., Albacete, J. L., Allanach, B., Alekhin, S., Allport, P., Andreev, V., Appleby, R. B., Arikan, E., Armesto, N., Azuelos, G., Bai, M., Barber, D., Bartels, J., Behnke, O., Behr, J., Belyaev, A. S., Ben-Zvi, I., Bernard, N., Bertolucci, S., Bettoni, S., Biswal, S., Blümlein, J., Böttcher, H., Bogacz, A., Bracco, C., Bracinik, J., Brandt, G., Braun, H., Brodsky, S., Brüning, O., Bulyak, E., Buniatyan, A., Burkhardt, H., Cakir, I. T., Cakir, O., Calaga, R., Caldwell, A., Cetinkaya, V., Chekelian, V., Ciapala, E., Ciftci, R., Ciftci, A. K., Cole, B. A., Collins, J. C., Dadoun, O., Dainton, J., Roeck, A. De., d'Enterria, D., DiNezza, P., D'Onofrio, M., Dudarev, A., Eide, A., Enberg, R., Eroglu, E., Eskola, K. J., Favart, L., Fitterer, M., Forte, S., Gaddi, A., Gambino, P., Morales, H. García, Gehrmann, T., Gladkikh, P., Glasman, C., Glazov, A., Godbole, R., Goddard, B., Greenshaw, T., Guffanti, A., Guzey, V., Gwenlan, C., Han, T., Hao, Y., Haug, F., Herr, W., Hervé, A., Holzer, B. J., Ishitsuka, M., Jacquet, M., Jeanneret, B., Jensen, E., Jimenez, J. M., Jowett, J. M., Jung, H., Karadeniz, H., Kayran, D., Kilic, A., Kimura, K., Klees, R., Klein, M., Klein, U., Kluge, T., Kocak, F., Korostelev, M., Kosmicki, A., Kostka, P., Kowalski, H., Kraemer, M., Kramer, G., Kuchler, D., Kuze, M., Lappi, T., Laycock, P., Levichev, E., Levonian, S., Litvinenko, V. N., Lombardi, A., Maeda, J., Marquet, C., Mellado, B., Mess, K. H., Milanese, A., Milhano, J. G., Moch, S., Morozov, I. I., Muttoni, Y., Myers, S., Nandi, S., Nergiz, Z., Newman, P. R., Omori, T., Osborne, J., Paoloni, E., Papaphilippou, Y., Pascaud, C., Paukkunen, H., Perez, E., Pieloni, T., Pilicer, E., Pire, B., Placakyte, R., Polini, A., Ptitsyn, V., Pupkov, Y., Radescu, V., Raychaudhuri, S., Rinolfi, L., Rizvi, E., Rohini, R., Rojo, J., Russenschuck, S., Sahin, M., Salgado, C. A., Sampei, K., Sassot, R., Sauvan, E., Schaefer, M., Schneekloth, U., Schörner-Sadenius, T., Schulte, D., Senol, A., Seryi, A., Sievers, P., Skrinsky, A. N., Smith, W., South, D., Spiesberger, H., Stasto, A. M., Strikman, M., Sullivan, M., Sultansoy, S., Sun, Y. P., Surrow, B., Szymanowski, L., Taels, P., Tapan, I., Tasci, T., Tassi, E., Kate, H. Ten., Terron, J., Thiesen, H., Thompson, L., Thompson, P., Tokushuku, K., García, R. Tomás, Tommasini, D., Trbojevic, D., Tsoupas, N., Tuckmantel, J., Turkoz, S., Trinh, T. N., Tywoniuk, K., Unel, G., Ullrich, T., Urakawa, J., VanMechelen, P., Variola, A., Veness, R., Vivoli, A., Vobly, P., Wagner, J., Wallny, R., Wallon, S., Watt, G., Weiss, C., Wiedemann, U. A., Wienands, U., Willeke, F., Xiao, B. -W., Yakimenko, V., Zarnecki, A. F., Zhang, Z., Zimmermann, F., Zlebcik, R., and Zomer, F.
Subjects: High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract: The present note relies on the recently published conceptual design report of the LHeC and extends the first contribution to the European strategy debate in emphasising the role of the LHeC to complement and complete the high luminosity LHC programme. The brief discussion therefore focuses on the importance of high precision PDF and $\alpha_s$ determinations for the physics beyond the Standard Model (GUTs, SUSY, Higgs). Emphasis is also given to the importance of high parton density phenomena in nuclei and their relevance to the heavy ion physics programme at the LHC.
Published: 2012

22. A Large Hadron Electron Collider at CERN

Author: Fernandez, J. L. Abelleira, Adolphsen, C., Adzic, P., Akay, A. N., Aksakal, H., Albacete, J. L., Allanach, B., Alekhin, S., Allport, P., Andreev, V., Appleby, R. B., Arikan, E., Armesto, N., Azuelos, G., Bai, M., Barber, D., Bartels, J., Behnke, O., Behr, J., Belyaev, A. S., Ben-Zvi, I., Bernard, N., Bertolucci, S., Bettoni, S., Biswal, S., Blümlein, J., Böttcher, H., Bogacz, A., Bracco, C., Bracinik, J., Brandt, G., Braun, H., Brodsky, S., Brüning, O., Bulyak, E., Buniatyan, A., Burkhardt, H., Cakir, I. T., Cakir, O., Calaga, R., Caldwell, A., Cetinkaya, V., Chekelian, V., Ciapala, E., Ciftci, R., Ciftci, A. K., Cole, B. A., Collins, J. C., Dadoun, O., Dainton, J., Roeck, A. De., d'Enterria, D., DiNezza, P., D'Onofrio, M., Dudarev, A., Eide, A., Enberg, R., Eroglu, E., Eskola, K. J., Favart, L., Fitterer, M., Forte, S., Gaddi, A., Gambino, P., Morales, H. García, Gehrmann, T., Gladkikh, P., Glasman, C., Glazov, A., Godbole, R., Goddard, B., Greenshaw, T., Guffanti, A., Guzey, V., Gwenlan, C., Han, T., Hao, Y., Haug, F., Herr, W., Hervé, A., Holzer, B. J., Ishitsuka, M., Jacquet, M., Jeanneret, B., Jensen, E., Jimenez, J. M., Jowett, J. M., Jung, H., Karadeniz, H., Kayran, D., Kilic, A., Kimura, K., Klees, R., Klein, M., Klein, U., Kluge, T., Kocak, F., Korostelev, M., Kosmicki, A., Kostka, P., Kowalski, H., Kraemer, M., Kramer, G., Kuchler, D., Kuze, M., Lappi, T., Laycock, P., Levichev, E., Levonian, S., Litvinenko, V. N., Lombardi, A., Maeda, J., Marquet, C., Mellado, B., Mess, K. H., Milanese, A., Milhano, J. G., Moch, S., Morozov, I. I., Muttoni, Y., Myers, S., Nandi, S., Nergiz, Z., Newman, P. R., Omori, T., Osborne, J., Paoloni, E., Papaphilippou, Y., Pascaud, C., Paukkunen, H., Perez, E., Pieloni, T., Pilicer, E., Pire, B., Placakyte, R., Polini, A., Ptitsyn, V., Pupkov, Y., Radescu, V., Raychaudhuri, S., Rinolfi, L., Rizvi, E., Rohini, R., Rojo, J., Russenschuck, S., Sahin, M., Salgado, C. A., Sampei, K., Sassot, R., Sauvan, E., Schaefer, M., Schneekloth, U., Schörner-Sadenius, T., Schulte, D., Senol, A., Seryi, A., Sievers, P., Skrinsky, A. N., Smith, W., South, D., Spiesberger, H., Stasto, A. M., Strikman, M., Sullivan, M., Sultansoy, S., Sun, Y. P., Surrow, B., Szymanowski, L., Taels, P., Tapan, I., Tasci, T., Tassi, E., Kate, H. Ten., Terron, J., Thiesen, H., Thompson, L., Thompson, P., Tokushuku, K., García, R. Tomás, Tommasini, D., Trbojevic, D., Tsoupas, N., Tuckmantel, J., Turkoz, S., Trinh, T. N., Tywoniuk, K., Unel, G., Ullrich, T., Urakawa, J., VanMechelen, P., Variola, A., Veness, R., Vivoli, A., Vobly, P., Wagner, J., Wallny, R., Wallon, S., Watt, G., Weiss, C., Wiedemann, U. A., Wienands, U., Willeke, F., Xiao, B. -W., Yakimenko, V., Zarnecki, A. F., Zhang, Z., Zimmermann, F., Zlebcik, R., and Zomer, F.
Subjects: High Energy Physics - Experiment, Physics - Accelerator Physics
Abstract: This document provides a brief overview of the recently published report on the design of the Large Hadron Electron Collider (LHeC), which comprises its physics programme, accelerator physics, technology and main detector concepts. The LHeC exploits and develops challenging, though principally existing, accelerator and detector technologies. This summary is complemented by brief illustrations of some of the highlights of the physics programme, which relies on a vastly extended kinematic range, luminosity and unprecedented precision in deep inelastic scattering. Illustrations are provided regarding high precision QCD, new physics (Higgs, SUSY) and electron-ion physics. The LHeC is designed to run synchronously with the LHC in the twenties and to achieve an integrated luminosity of O(100) fb$^{-1}$. It will become the cleanest high resolution microscope of mankind and will substantially extend as well as complement the investigation of the physics of the TeV energy scale, which has been enabled by the LHC.
Published: 2012

23. A Large Hadron Electron Collider at CERN: Report on the Physics and Design Concepts for Machine and Detector

Author: Fernandez, J. L. Abelleira, Adolphsen, C., Akay, A. N., Aksakal, H., Albacete, J. L., Alekhin, S., Allport, P., Andreev, V., Appleby, R. B., Arikan, E., Armesto, N., Azuelos, G., Bai, M., Barber, D., Bartels, J., Behnke, O., Behr, J., Belyaev, A. S., Ben-Zvi, I., Bernard, N., Bertolucci, S., Bettoni, S., Biswal, S., Blümlein, J., Böttcher, H., Bogacz, A., Bracco, C., Brandt, G., Braun, H., Brodsky, S., Brüning, O., Bulyak, E., Buniatyan, A., Burkhardt, H., Cakir, I. T., Cakir, O., Calaga, R., Cetinkaya, V., Ciapala, E., Ciftci, R., Ciftci, A. K., Cole, B. A., Collins, J. C., Dadoun, O., Dainton, J., Roeck, A. De., d'Enterria, D., Dudarev, A., Eide, A., Enberg, R., Eroglu, E., Eskola, K. J., Favart, L., Fitterer, M., Forte, S., Gaddi, A., Gambino, P., Morales, H. García, Gehrmann, T., Gladkikh, P., Glasman, C., Godbole, R., Goddard, B., Greenshaw, T., Guffanti, A., Guzey, V., Gwenlan, C., Han, T., Hao, Y., Haug, F., Herr, W., Hervé, A., Holzer, B. J., Ishitsuka, M., Jacquet, M., Jeanneret, B., Jimenez, J. M., Jowett, J. M., Jung, H., Karadeniz, H., Kayran, D., Kilic, A., Kimura, K., Klein, M., Klein, U., Kluge, T., Kocak, F., Korostelev, M., Kosmicki, A., Kostka, P., Kowalski, H., Kramer, G., Kuchler, D., Kuze, M., Lappi, T., Laycock, P., Levichev, E., Levonian, S., Litvinenko, V. N., Lombardi, A., Maeda, J., Marquet, C., Maxfield, S. J., Mellado, B., Mess, K. H., Milanese, A., Moch, S., Morozov, I. I., Muttoni, Y., Myers, S., Nandi, S., Nergiz, Z., Newman, P. R., Omori, T., Osborne, J., Paoloni, E., Papaphilippou, Y., Pascaud, C., Paukkunen, H., Perez, E., Pieloni, T., Pilicer, E., Pire, B., Placakyte, R., Polini, A., Ptitsyn, V., Pupkov, Y., Radescu, V., Raychaudhuri, S., Rinolfi, L., Rohini, R., Rojo, J., Russenschuck, S., Sahin, M., Salgado, C. A., Sampei, K., Sassot, R., Sauvan, E., Schneekloth, U., Schörner-Sadenius, T., Schulte, D., Senol, A., Seryi, A., Sievers, P., Skrinsky, A. N., Smith, W., Spiesberger, H., Stasto, A. M., Strikman, M., Sullivan, M., Sultansoy, S., Sun, Y. P., Surrow, B., Szymanowski, L., Taels, P., Tapan, I., Tasci, A. T., Tassi, E., Kate, H. Ten., Terron, J., Thiesen, H., Thompson, L., Tokushuku, K., García, R. Tomás, Tommasini, D., Trbojevic, D., Tsoupas, N., Tuckmantel, J., Turkoz, S., Trinh, T. N., Tywoniuk, K., Unel, G., Urakawa, J., VanMechelen, P., Variola, A., Veness, R., Vivoli, A., Vobly, P., Wagner, J., Wallny, R., Wallon, S., Watt, G., Weiss, C., Wiedemann, U. A., Wienands, U., Willeke, F., Xiao, B. -W., Yakimenko, V., Zarnecki, A. F., Zhang, Z., Zimmermann, F., Zlebcik, R., and Zomer, F.
Subjects: Physics - Accelerator Physics, High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract: The physics programme and the design are described of a new collider for particle and nuclear physics, the Large Hadron Electron Collider (LHeC), in which a newly built electron beam of 60 GeV, up to possibly 140 GeV, energy collides with the intense hadron beams of the LHC. Compared to HERA, the kinematic range covered is extended by a factor of twenty in the negative four-momentum squared, $Q^2$, and in the inverse Bjorken $x$, while with the design luminosity of $10^{33}$ cm$^{-2}$s$^{-1}$ the LHeC is projected to exceed the integrated HERA luminosity by two orders of magnitude. The physics programme is devoted to an exploration of the energy frontier, complementing the LHC and its discovery potential for physics beyond the Standard Model with high precision deep inelastic scattering measurements. These are designed to investigate a variety of fundamental questions in strong and electroweak interactions. The physics programme also includes electron-deuteron and electron-ion scattering in a $(Q^2, 1/x)$ range extended by four orders of magnitude as compared to previous lepton-nucleus DIS experiments for novel investigations of neutron's and nuclear structure, the initial conditions of Quark-Gluon Plasma formation and further quantum chromodynamic phenomena. The LHeC may be realised either as a ring-ring or as a linac-ring collider. Optics and beam dynamics studies are presented for both versions, along with technical design considerations on the interaction region, magnets and further components, together with a design study for a high acceptance detector. Civil engineering and installation studies are presented for the accelerator and the detector. The LHeC can be built within a decade and thus be operated while the LHC runs in its high-luminosity phase. It thus represents a major opportunity for progress in particle physics exploiting the investment made in the LHC.
Published: 2012
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24. Injection and dump considerations for a 16.5 TeV HE-LHC

Author: Goddard, B., Barnes, M., Bartmann, W., Borburgh, J., Bracco, C., Ducimetière, L., Kain, V., Meddahi, M., Mertens, V., Senaj, V., and Uythoven, J.
Subjects: Physics - Accelerator Physics
Abstract: Injection and beam dumping is considered for a 16.5 TeV hadron accelerator in the current LHC tunnel, with an injection energy in the range 1 - 1.3 TeV. The present systems are described and the possible upgrade scenarios investigated for higher beam rigidity. In addition to the required equipment performance, the machine protection related aspects are explored. The expected constraints on the machine layout are also given. The technological challenges for the different equipment subsystems are detailed, and areas where R&D is necessary are highlighted., Comment: 6 pages, contribution to the EuCARD-AccNet-EuroLumi Workshop: The High-Energy Large Hadron Collider, Malta, 14 -- 16 Oct 2010; CERN Yellow Report CERN-2011-003, pp. 128-133
Published: 2011

25. The UA9 experimental layout

Author: Scandale, W., Arduini, G., Assmann, R., Bracco, C., Cerutti, F., Christiansen, J., Gilardoni, S., Laface, E., Losito, R., Masi, A., Metral, E., Mirarchi, D., Montesano, S., Previtali, V., Redaelli, S., Valentino, G., Schoofs, P., Smirnov, G., Tlustos, L., Bagli, E., Baricordi, S., Dalpiaz, P., Guidi, V., Mazzolari, A., Vincenzi, D., Dabagov, S., Murtas, F., Carnera, A., Della Mea, G., De Salvador, D., Lombardi, A., Lytovchenko, O., Tonezzer, M., Cavoto, G., Ludovici, L., Santacesaria, R., Valente, P., Galluccio, F., Afonin, A. G., Bulgakov, M. K., Chesnokov, Yu. A., Maisheev, V. A., Yazynin, I. A., Kovalenko, A. D., Taratin, A. M., Gavrikov, Yu. A., Ivanov, Yu. M., Lapina, L. P., Skorobogatov, V. V., Ferguson, W., Fulcher, J., Hall, G., Pesaresi, M., Raymond, M., Rose, A., Ryan, M., Zorba, O., Robert-Demolaize, G., Markiewicz, T., Oriunno, M., and Wienands, U.
Subjects: Physics - Accelerator Physics
Abstract: The UA9 experimental equipment was installed in the CERN-SPS in March '09 with the aim of investigating crystal assisted collimation in coasting mode. Its basic layout comprises silicon bent crystals acting as primary collimators mounted inside two vacuum vessels. A movable 60 cm long block of tungsten located downstream at about 90 degrees phase advance intercepts the deflected beam. Scintillators, Gas Electron Multiplier chambers and other beam loss monitors measure nuclear loss rates induced by the interaction of the beam halo in the crystal. Roman pots are installed in the path of the deflected particles and are equipped with a Medipix detector to reconstruct the transverse distribution of the impinging beam. Finally UA9 takes advantage of an LHC-collimator prototype installed close to the Roman pot to help in setting the beam conditions and to analyze the efficiency to deflect the beam. This paper describes in details the hardware installed to study the crystal collimation during 2010., Comment: 15pages, 11 figure, submitted to JINST
Published: 2011
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26. Measurements of heavy ion beam losses from collimation

Author: Bruce, R., Assmann, R. W., Bellodi, G., Bracco, C., Braun, H. H., Gilardoni, S., Holzer, E. B., Jowett, J. M., Redaelli, S., and Weiler, T.
Subjects: Physics - Accelerator Physics
Abstract: The collimation efficiency for Pb ion beams in the LHC is predicted to be lower than requirements. Nuclear fragmentation and electromagnetic dissociation in the primary collimators create fragments with a wide range of Z/A ratios, which are not intercepted by the secondary collimators but lost where the dispersion has grown sufficiently large. In this article we present measurements and simulations of loss patterns generated by a prototype LHC collimator in the CERN SPS. Measurements were performed at two different energies and angles of the collimator. We also compare with proton loss maps and find a qualitative difference between Pb ions and protons, with the maximum loss rate observed at different places in the ring. This behavior was predicted by simulations and provides a valuable benchmark of our understanding of ion beam losses caused by collimation., Comment: 12 pages, 20 figures
Published: 2009
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27. A simple derivation of Kepler's laws without solving differential equations

Author: Provost, J. -P. and Bracco, C.
Subjects: Physics - Popular Physics, Physics - History and Philosophy of Physics
Abstract: Proceeding like Newton with a discrete time approach of motion and a geometrical representation of velocity and acceleration, we obtain Kepler's laws without solving differential equations. The difficult part of Newton's work, when it calls for non trivial properties of ellipses, is avoided by the introduction of polar coordinates. Then a simple reconsideration of Newton's figure naturally leads to en explicit expression of the velocity and to the equation of the trajectory. This derivation, which can be fully apprehended by beginners at university (or even before) can be considered as a first application of mechanical concepts to a physical problem of great historical and pedagogical interest.
Published: 2008
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28. A Pedagogical Discussion Concerning the Gravitational Energy Radiated by Keplerian Systems

Author: Bracco, C., Provost, J. -P., and Salati, P.
Subjects: Physics - Popular Physics, Physics - General Physics
Abstract: We first discuss the use of dimensional arguments (and of the quadrupolar emission hypothesis) in the derivation of the gravitational power radiated on a circular orbit. Then, we show how to simply obtain the instantaneous power radiated on a general Keplerian orbit by approximating it locally by a circle. This allows recovering with a good precision, in the case of an ellipse, the highly non trivial dependence on the eccentricity of the average power given by general relativity. The whole approach is understandable by undergraduate students., Comment: A simpler method has been used in the calculations, which requires now only standard knowledge (the radius of curvature is defined by the normal acceleration). Two figures have been added. Concerning the dimensional analysis, the comparison with electromagnetism has been detailed
Published: 2008
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29. The electron accelerators for the AWAKE experiment at CERN—Baseline and Future Developments

Author: Pepitone, K., Doebert, S., Apsimon, R., Bauche, J., Bernardini, M., Bracco, C., Burt, G., Chauchet, A., Chevallay, E., Chritin, N., Curt, S., Damerau, H., Kelisani, M. Dayyani, Delory, C., Fedosseev, V., Friebel, F., Galleazzi, F., Gorgisyan, I., Gschwendtner, E., Hansen, J., Jensen, L., Keeble, F., Maricalva, L., Mazzoni, S., McMonagle, G., Mete, O., Pardons, A., Pasquino, C., Verzilov, V., Schmidt, J.S., Soby, L., Williamson, B., Yamakawa, E., Pitman, S., and Mitchell, J.
Published: 2018
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30. Predicting locally advanced rectal cancer response to neoadjuvant therapy with 18F-FDG PET and MRI radiomics features

Author: Giannini, V., Mazzetti, S., Bertotto, I., Chiarenza, C., Cauda, S., Delmastro, E., Bracco, C., Di Dia, A., Leone, F., Medico, E., Pisacane, A., Ribero, D., Stasi, M., and Regge, D.
Published: 2019
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31. Scintillation in scalar-tensor theories of gravity

Author: Bracco, C. and Teyssandier, P.
Subjects: General Relativity and Quantum Cosmology
Abstract: We study the scintillation produced by time-varying gravitational fields within scalar-tensor theories of gravity. The problem is treated in the geometrical optics approximation for a very distant light source emitting quasi plane monochromatic electromagnetic waves. We obtain a general formula giving the time dependence of the photon flux received by a freely falling observer. In the weak-field approximation, we show that the contribution to the scintillation effect due to the focusing of the light beam by a gravitational wave is of first order in the amplitude of the scalar perturbation. Thus scalar-tensor theories contrast with general relativity, which predicts that the only first-order effect is due to the spectral shift. Moreover, we find that the scintillation effects caused by the scalar field have a local character: they depend only on the value of the perturbation at the observer. This effect provides in principle a mean to detect the presence of a long range scalar field in the Universe, but its smallness constitutes a tremendous challenge for detection., Comment: 8 pages; to appear in Astronomy and Astrophysics
Published: 1998

32. Reaching record-low [formula omitted] at the CERN Large Hadron Collider using a novel scheme of collimator settings and optics

Author: Bruce, R., Bracco, C., De Maria, R., Giovannozzi, M., Mereghetti, A., Mirarchi, D., Redaelli, S., Quaranta, E., and Salvachua, B.
Published: 2017
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33. Tailoring transverse beam characteristics with the new CERN PS Booster charge-exchange injection system.

Author: Renner, E, Albright, S, Antoniou, F, Asvesta, F, Bartosik, H, Bracco, C, Di Giovanni, G P, Mikulec, B, Prebibaj, T, Skowronski, P, and Velotti, F M
Published: 2023
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34. First results of running the LHC with lead ions at a beam energy of 6.8 Z TeV.

Author: Bruce, R., Alemany Fernandez, R., Argyropoulos, T., Bartosik, H., Bracco, C., Cai, R., D'Andrea, M., Frasca, A., Hermes, P., Jowett, J.M., Mirarchi, D., Redaelli, S., Solfaroli, M., Triantafyllou, N., and Wenninger, J.
Published: 2023
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35. Quality indicators in the intensity modulated/image-guided radiotherapy era

Author: Gabriele, P., Maggio, A., Garibaldi, E., Bracco, C., Delmastro, E., Gabriele, D., Rosi, A., Munoz, F., Di Muzio, N., Corvò, R., and Stasi, M.
Published: 2016
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36. AWAKE, The Advanced Proton Driven Plasma Wakefield Acceleration Experiment at CERN

Author: Gschwendtner, E., Adli, E., Amorim, L., Apsimon, R., Assmann, R., Bachmann, A.-M., Batsch, F., Bauche, J., Berglyd Olsen, V.K., Bernardini, M., Bingham, R., Biskup, B., Bohl, T., Bracco, C., Burrows, P.N., Burt, G., Buttenschön, B., Butterworth, A., Caldwell, A., Cascella, M., Chevallay, E., Cipiccia, S., Damerau, H., Deacon, L., Dirksen, P., Doebert, S., Dorda, U., Farmer, J., Fedosseev, V., Feldbaumer, E., Fiorito, R., Fonseca, R., Friebel, F., Gorn, A.A., Grulke, O., Hansen, J., Hessler, C., Hofle, W., Holloway, J., Hüther, M., Jaroszynski, D., Jensen, L., Jolly, S., Joulaei, A., Kasim, M., Keeble, F., Li, Y., Liu, S., Lopes, N., Lotov, K.V., Mandry, S., Martorelli, R., Martyanov, M., Mazzoni, S., Mete, O., Minakov, V.A., Mitchell, J., Moody, J., Muggli, P., Najmudin, Z., Norreys, P., Öz, E., Pardons, A., Pepitone, K., Petrenko, A., Plyushchev, G., Pukhov, A., Rieger, K., Ruhl, H., Salveter, F., Savard, N., Schmidt, J., Seryi, A., Shaposhnikova, E., Sheng, Z.M., Sherwood, P., Silva, L., Soby, L., Sosedkin, A.P., Spitsyn, R.I., Trines, R., Tuev, P.V., Turner, M., Verzilov, V., Vieira, J., Vincke, H., Wei, Y., Welsch, C.P., Wing, M., Xia, G., and Zhang, H.
Published: 2016
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37. Status of the proton and electron transfer lines for the AWAKE Experiment at CERN

Author: Schmidt, J.S., Bauche, J., Biskup, B., Bracco, C., Doebert, S., Goddard, B., Gschwendtner, E., Jensen, L.K., Jones, O.R., Mazzoni, S., Meddahi, M., Pepitone, K., Petrenko, A., Velotti, F.M., and Vorozhtsov, A.
Published: 2016
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38. Path to AWAKE: Evolution of the concept

Author: Caldwell, A., Adli, E., Amorim, L., Apsimon, R., Argyropoulos, T., Assmann, R., Bachmann, A.-M., Batsch, F., Bauche, J., Berglyd Olsen, V.K., Bernardini, M., Bingham, R., Biskup, B., Bohl, T., Bracco, C., Burrows, P.N., Burt, G., Buttenschön, B., Butterworth, A., Cascella, M., Chattopadhyay, S., Chevallay, E., Cipiccia, S., Damerau, H., Deacon, L., Dirksen, P., Doebert, S., Dorda, U., Elsen, E., Farmer, J., Fartoukh, S., Fedosseev, V., Feldbaumer, E., Fiorito, R., Fonseca, R., Friebel, F., Geschonke, G., Goddard, B., Gorn, A.A., Grulke, O., Gschwendtner, E., Hansen, J., Hessler, C., Hillenbrand, S., Hofle, W., Holloway, J., Huang, C., Hüther, M., Jaroszynski, D., Jensen, L., Jolly, S., Joulaei, A., Kasim, M., Keeble, F., Kersevan, R., Kumar, N., Li, Y., Liu, S., Lopes, N., Lotov, K.V., Lu, W., Machacek, J., Mandry, S., Martin, I., Martorelli, R., Martyanov, M., Mazzoni, S., Meddahi, M., Merminga, L., Mete, O., Minakov, V.A., Mitchell, J., Moody, J., Müller, A.-S., Najmudin, Z., Noakes, T.C.Q., Norreys, P., Osterhoff, J., Öz, E., Pardons, A., Pepitone, K., Petrenko, A., Plyushchev, G., Pozimski, J., Pukhov, A., Reimann, O., Rieger, K., Roesler, S., Ruhl, H., Rusnak, T., Salveter, F., Savard, N., Schmidt, J., von der Schmitt, H., Seryi, A., Shaposhnikova, E., Sheng, Z.M., Sherwood, P., Silva, L., Simon, F., Soby, L., Sosedkin, A.P., Spitsyn, R.I., Tajima, T., Tarkeshian, R., Timko, H., Trines, R., Tückmantel, T., Tuev, P.V., Turner, M., Velotti, F., Verzilov, V., Vieira, J., Vincke, H., Wei, Y., Welsch, C.P., Wing, M., Xia, G., Yakimenko, V., Zhang, H., and Zimmermann, F.
Published: 2016
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39. CDKN2A and BAP1 germline mutations predispose to melanoma and mesothelioma

Author: Betti, M., Aspesi, A., Biasi, A., Casalone, E., Ferrante, D., Ogliara, P., Gironi, L.C., Giorgione, R., Farinelli, P., Grosso, F., Libener, R., Rosato, S., Turchetti, D., Maffè, A., Casadio, C., Ascoli, V., Dianzani, C., Colombo, E., Piccolini, E., Pavesi, M., Miccoli, S., Mirabelli, D., Bracco, C., Righi, L., Boldorini, R., Papotti, M., Matullo, G., Magnani, C., Pasini, B., and Dianzani, I.
Published: 2016
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40. AWAKE: A Proton-Driven Plasma Wakefield Acceleration Experiment at CERN

Author: Bracco, C., Amorim, L.D., Assmann, R., Batsch, F., Bingham, R., Burt, G., Buttenschön, B., Butterworth, A., Caldwell, A., Chattopadhyay, S., Cipiccia, S., Deacon, L.C., Doebert, S., Dorda, U., Feldbaumer, E., Fonseca, R.A., Fedossev, V., Goddard, B., Grebenyuk, J., Grulke, O., Gschwendtner, E., Hansen, J., Hessler, C., Hofle, W., Holloway, J., Jaroszynski, D., Jenkins, M., Jensen, L., Jolly, S., Jones, R., Kasim, M.F., Lopes, N., Lotov, K., Mandry, S.R., Martyanov, M., Meddahi, M., Mete, O., Minakov, V., Moody, J., Muggli, P., Najmudin, Z., Norreys, P.A., Öz, E., Pardons, A., Petrenko, A., Pukhov, A., Rieger, K., Reimann, O., Seryi, A.A., Shaposhnikova, E., Sherwood, P., Silva, L.O., Sosedkin, A., Tarkeshian, R., Trines, R.M.G.M., Velotti, F.M., Vieira, J., Vincke, H., Welsch, C., Wing, M., and Xia, G.
Published: 2016
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41. Pattern of comorbidities and 1-year mortality in elderly patients with COPD hospitalized in internal medicine wards: data from the RePoSI Registry

Author: Argano, C, Scichilone, N, Natoli, G, Nobili, A, Corazza, G, Mannucci, P, Perticone, F, Corrao, S, Pietrangelo, A, Licata, G, Violi, F, Marengoni, A, Salerno, F, Cesari, M, Tettamanti, M, Pasina, L, Franchi, C, Miglio, G, Cortesi, L, Ardoino, I, Novella, A, Prisco, D, Silvestri, E, Emmi, G, Bettiol, A, Caterina, C, Biolo, G, Zanetti, M, Guadagni, M, Zaccari, M, Chiuch, M, Vanoli, M, Grignani, G, Pulixi, E, Bernardi, M, Bassi, S, Santi, L, Zaccherini, G, Lupattelli, G, Mannarino, E, Bianconi, V, Paciullo, F, Alcidi, R, Nuti, R, Valenti, R, Ruvio, M, Cappelli, S, Palazzuoli, A, Girelli, D, Busti, F, Marchi, G, Barbagallo, M, Dominguez, L, Cocita, F, Beneduce, V, Plances, L, Mularo, S, Raspanti, M, Cavallaro, F, Zoli, M, Lazzari, I, Brunori, M, Fabbri, E, Magalotti, D, Arno, R, Pasini, F, Capecchi, P, Palasciano, G, Modeo, M, Di Gennaro, C, Cappellini, M, Maira, D, Di Stefano, V, Fabio, G, Seghezzi, S, Mancarella, M, De Amicis, M, De Luca, G, Scaramellini, N, Rossi, P, Damanti, S, Clerici, M, Conti, F, Bonini, G, Ottolini, B, Di Sabatino, A, Miceli, E, Lenti, M, Pisati, M, Dominioni, C, Murialdo, G, Marra, A, Cattaneo, F, Pontremoli, R, Beccati, V, Nobili, G, Secchi, M, Ghelfi, D, Anastasio, L, Sofia, L, Carbone, M, Cipollone, F, Guagnano, M, Valeriani, E, Rossi, I, Mancuso, G, Calipari, D, Bartone, M, Delitala, G, Berria, M, Pes, C, Delitala, A, Muscaritoli, M, Molfino, A, Petrillo, E, Zuccala, G, D'Aurizio, G, Romanelli, G, Zucchelli, A, Manzoni, F, Volpini, A, Picardi, A, Gentilucci, U, Gallo, P, Dell'Unto, C, Annoni, G, Corsi, M, Bellelli, G, Zazzetta, S, Mazzola, P, Szabo, H, Bonfanti, A, Arturi, F, Succurro, E, Rubino, M, Tassone, B, Sesti, G, Serra, M, Bleve, M, Gasbarrone, L, Sajeva, M, Brucato, A, Ghidoni, S, Fabris, F, Bertozzi, I, Bogoni, G, Rabuini, M, Cosi, E, Scarinzi, P, Amabile, A, Omenetto, E, Prandini, T, Manfredini, R, Fabbian, F, Boari, B, De Giorgi, A, Tiseo, R, De Giorgio, R, Paolisso, G, Rizzo, M, Borghi, C, Strocchi, E, Ianniello, E, Soldati, M, Sabba, C, Vella, F, Suppressa, P, Schilardi, A, Loparco, F, De Vincenzo, G, Comitangelo, A, Amoruso, E, Fenoglio, L, Falcetta, A, Bracco, C, Fracanzani Silvia Fargion, A, Tiraboschi, S, Cespiati, A, Oberti, G, Sigon, G, Peyvandi, F, Rossio, R, Ferrari, B, Colombo, G, Agosti, P, Monzani, V, Savojardo, V, Folli, C, Ceriani, G, Pallini, G, Dallegri, F, Ottonello, L, Liberale, L, Caserza, L, Salam, K, Liberato, N, Tognin, T, Bianchi, G, Giaquinto, S, Purrello, F, Di Pino, A, Piro, S, Rozzini, R, Falanga, L, Spazzini, E, Ferrandina, C, Montrucchio, G, Petitti, P, Peasso, P, Favale, E, Poletto, C, Salmi, R, Gaudenzi, P, Perri, L, Landolfi, R, Montalto, M, Mirijello, A, Guasti, L, Castiglioni, L, Maresca, A, Squizzato, A, Campiotti, L, Grossi, A, Bertolotti, M, Mussi, C, Lancellotti, G, Libbra, M, Dondi, G, Pellegrini, E, Carulli, L, Galassi, M, Grassi, Y, Perticone, M, Battaglia, R, Filice, M, Maio, R, Stanghellini, V, Ruggeri, E, del Vecchio, S, Salvi, A, Leonardi, R, Damiani, G, Capeci, W, Gabrielli, A, Mattioli, M, Martino, G, Biondi, L, Pettinari, P, Ghio, R, Col, A, Minisola, S, Colangelo, L, Cilli, M, Labbadia, G, Afeltra, A, Marigliano, B, Pipita, M, Castellino, P, Zanoli, L, Pignataro, S, Gennaro, A, Blanco, J, Saracco, V, Fogliati, M, Bussolino, C, Mete, F, Gino, M, Cittadini, A, Vigorito, C, Arcopinto, M, Salzano, A, Bobbio, E, Sirico, D, Moreo, G, Gasparini, F, Prolo, S, Pina, G, Ballestrero, A, Ferrando, F, Berra, S, Dassi, S, Nava, M, Graziella, B, Baldassarre, S, Fragapani, S, Gruden, G, Galanti, G, Mascherini, G, Petri, C, Stefani, L, Girino, M, Piccinelli, V, Nasso, F, Gioffre, V, Pasquale, M, Scattolin, G, Martinelli, S, Turrin, M, Sechi, L, Catena, C, Colussi, G, Passariello, N, Rinaldi, L, Berti, F, Famularo, G, Tarsitani, P, Castello, R, Pasino, M, Ceda, G, Maggio, M, Morganti, S, Artoni, A, Del Giacco, S, Firinu, D, Losa, F, Paoletti, G, Costanzo, G, Montalto, G, Licata, A, Malerba, V, Montalto, F, Lasco, A, Basile, G, Catalano, A, Malatino, L, Stancanelli, B, Terranova, V, Di Marca, S, Di Quattro, R, La Malfa, L, Caruso, R, Mecocci, P, Ruggiero, C, Boccardi, V, Meschi, T, Lauretani, F, Ticinesi, A, Nouvenne, A, Minuz, P, Fondrieschi, L, Pirisi, M, Fra, G, Sola, D, Porta, M, Riva, P, Quadri, R, Larovere, E, Novelli, M, Scanzi, G, Mengoli, C, Provini, S, Ricevuti, L, Simeone, E, Scurti, R, Tolloso, F, Tarquini, R, Valoriani, A, Dolenti, S, Vannini, G, Tedeschi, A, Trotta, L, Volpi, R, Bocchi, P, Vignali, A, Harari, S, Lonati, C, Cattaneo, M, Napoli, F, Argano C., Scichilone N., Natoli G., Nobili A., Corazza G. R., Mannucci P. M., Perticone F., Corrao S., Pietrangelo A., Licata G., Violi F., Marengoni A., Salerno F., Cesari M., Tettamanti M., Pasina L., Franchi C., Miglio G., Cortesi L., Ardoino I., Novella A., Prisco D., Silvestri E., Emmi G., Bettiol A., Caterina C., Biolo G., Zanetti M., Guadagni M., Zaccari M., Chiuch M., Vanoli M., Grignani G., Pulixi E. A., Bernardi M., Bassi S. L., Santi L., Zaccherini G., Lupattelli G., Mannarino E., Bianconi V., Paciullo F., Alcidi R., Nuti R., Valenti R., Ruvio M., Cappelli S., Palazzuoli A., Girelli D., Busti F., Marchi G., Barbagallo M., Dominguez L., Cocita F., Beneduce V., Plances L., Mularo S., Raspanti M., Cavallaro F., Zoli M., Lazzari I., Brunori M., Fabbri E., Magalotti D., Arno R., Pasini F. L., Capecchi P. L., Palasciano G., Modeo M. E., Di Gennaro C., Cappellini M. D., Maira D., Di Stefano V., Fabio G., Seghezzi S., Mancarella M., De Amicis M. M., De Luca G., Scaramellini N., Rossi P. D., Damanti S., Clerici M., Conti F., Bonini G., Ottolini B. B., Di Sabatino A., Miceli E., Lenti M. V., Pisati M., Dominioni C. C., Murialdo G., Marra A., Cattaneo F., Pontremoli R., Beccati V., Nobili G., Secchi M. B., Ghelfi D., Anastasio L., Sofia L., Carbone M., Cipollone F., Guagnano M. T., Valeriani E., Rossi I., Mancuso G., Calipari D., Bartone M., Delitala G., Berria M., Pes C., Delitala A., Muscaritoli M., Molfino A., Petrillo E., Zuccala G., D'Aurizio G., Romanelli G., Zucchelli A., Manzoni F., Volpini A., Picardi A., Gentilucci U. V., Gallo P., Dell'Unto C., Annoni G., Corsi M., Bellelli G., Zazzetta S., Mazzola P., Szabo H., Bonfanti A., Arturi F., Succurro E., Rubino M., Tassone B., Sesti G., Serra M. G., Bleve M. A., Gasbarrone L., Sajeva M. R., Brucato A., Ghidoni S., Fabris F., Bertozzi I., Bogoni G., Rabuini M. V., Cosi E., Scarinzi P., Amabile A., Omenetto E., Prandini T., Manfredini R., Fabbian F., Boari B., De Giorgi A., Tiseo R., De Giorgio R., Paolisso G., Rizzo M. R., Borghi C., Strocchi E., Ianniello E., Soldati M., Sabba C., Vella F. S., Suppressa P., Schilardi A., Loparco F., De Vincenzo G. M., Comitangelo A., Amoruso E., Fenoglio L., Falcetta A., Bracco C., Fracanzani Silvia Fargion A. L., Tiraboschi S., Cespiati A., Oberti G., Sigon G., Peyvandi F., Rossio R., Ferrari B., Colombo G., Agosti P., Monzani V., Savojardo V., Folli C., Ceriani G., Pallini G., Dallegri F., Ottonello L., Liberale L., Caserza L., Salam K., Liberato N. L., Tognin T., Bianchi G. B., Giaquinto S., Purrello F., Di Pino A., Piro S., Rozzini R., Falanga L., Spazzini E., Ferrandina C., Montrucchio G., Petitti P., Peasso P., Favale E., Poletto C., Salmi R., Gaudenzi P., Perri L., Landolfi R., Montalto M., Mirijello A., Guasti L., Castiglioni L., Maresca A., Squizzato A., Campiotti L., Grossi A., Bertolotti M., Mussi C., Lancellotti G., Libbra M. V., Dondi G., Pellegrini E., Carulli L., Galassi M., Grassi Y., Perticone M., Battaglia R., FIlice M., Maio R., Stanghellini V., Ruggeri E., del Vecchio S., Salvi A., Leonardi R., Damiani G., Capeci W., Gabrielli A., Mattioli M., Martino G. P., Biondi L., Pettinari P., Ghio R., Col A. D., Minisola S., Colangelo L., Cilli M., Labbadia G., Afeltra A., Marigliano B., Pipita M. E., Castellino P., Zanoli L., Pignataro S., Gennaro A., Blanco J., Saracco V., Fogliati M., Bussolino C., Mete F., Gino M., Cittadini A., Vigorito C., Arcopinto M., Salzano A., Bobbio E., Marra A. M., Sirico D., Moreo G., Gasparini F., Prolo S., Pina G., Ballestrero A., Ferrando F., Berra S., Dassi S., Nava M. C., Graziella B., Baldassarre S., Fragapani S., Gruden G., Galanti G., Mascherini G., Petri C., Stefani L., Girino M., Piccinelli V., Nasso F., Gioffre V., Pasquale M., Scattolin G., Martinelli S., Turrin M., Sechi L., Catena C., Colussi G., Passariello N., Rinaldi L., Berti F., Famularo G., Tarsitani P., Castello R., Pasino M., Ceda G. P., Maggio M. G., Morganti S., Artoni A., Del Giacco S., Firinu D., Losa F., Paoletti G., Costanzo G., Montalto G., Licata A., Malerba V., Montalto F. A., Lasco A., Basile G., Catalano A., Malatino L., Stancanelli B., Terranova V., Di Marca S., Di Quattro R., La Malfa L., Caruso R., Mecocci P., Ruggiero C., Boccardi V., Meschi T., Lauretani F., Ticinesi A., Nouvenne A., Minuz P., Fondrieschi L., Pirisi M., Fra G. P., Sola D., Porta M., Riva P., Quadri R., Larovere E., Novelli M., Scanzi G., Mengoli C., Provini S., Ricevuti L., Simeone E., Scurti R., Tolloso F., Tarquini R., Valoriani A., Dolenti S., Vannini G., Tedeschi A., Trotta L., Volpi R., Bocchi P., Vignali A., Harari S., Lonati C., Cattaneo M., Napoli F., Argano, C, Scichilone, N, Natoli, G, Nobili, A, Corazza, G, Mannucci, P, Perticone, F, Corrao, S, Pietrangelo, A, Licata, G, Violi, F, Marengoni, A, Salerno, F, Cesari, M, Tettamanti, M, Pasina, L, Franchi, C, Miglio, G, Cortesi, L, Ardoino, I, Novella, A, Prisco, D, Silvestri, E, Emmi, G, Bettiol, A, Caterina, C, Biolo, G, Zanetti, M, Guadagni, M, Zaccari, M, Chiuch, M, Vanoli, M, Grignani, G, Pulixi, E, Bernardi, M, Bassi, S, Santi, L, Zaccherini, G, Lupattelli, G, Mannarino, E, Bianconi, V, Paciullo, F, Alcidi, R, Nuti, R, Valenti, R, Ruvio, M, Cappelli, S, Palazzuoli, A, Girelli, D, Busti, F, Marchi, G, Barbagallo, M, Dominguez, L, Cocita, F, Beneduce, V, Plances, L, Mularo, S, Raspanti, M, Cavallaro, F, Zoli, M, Lazzari, I, Brunori, M, Fabbri, E, Magalotti, D, Arno, R, Pasini, F, Capecchi, P, Palasciano, G, Modeo, M, Di Gennaro, C, Cappellini, M, Maira, D, Di Stefano, V, Fabio, G, Seghezzi, S, Mancarella, M, De Amicis, M, De Luca, G, Scaramellini, N, Rossi, P, Damanti, S, Clerici, M, Conti, F, Bonini, G, Ottolini, B, Di Sabatino, A, Miceli, E, Lenti, M, Pisati, M, Dominioni, C, Murialdo, G, Marra, A, Cattaneo, F, Pontremoli, R, Beccati, V, Nobili, G, Secchi, M, Ghelfi, D, Anastasio, L, Sofia, L, Carbone, M, Cipollone, F, Guagnano, M, Valeriani, E, Rossi, I, Mancuso, G, Calipari, D, Bartone, M, Delitala, G, Berria, M, Pes, C, Delitala, A, Muscaritoli, M, Molfino, A, Petrillo, E, Zuccala, G, D'Aurizio, G, Romanelli, G, Zucchelli, A, Manzoni, F, Volpini, A, Picardi, A, Gentilucci, U, Gallo, P, Dell'Unto, C, Annoni, G, Corsi, M, Bellelli, G, Zazzetta, S, Mazzola, P, Szabo, H, Bonfanti, A, Arturi, F, Succurro, E, Rubino, M, Tassone, B, Sesti, G, Serra, M, Bleve, M, Gasbarrone, L, Sajeva, M, Brucato, A, Ghidoni, S, Fabris, F, Bertozzi, I, Bogoni, G, Rabuini, M, Cosi, E, Scarinzi, P, Amabile, A, Omenetto, E, Prandini, T, Manfredini, R, Fabbian, F, Boari, B, De Giorgi, A, Tiseo, R, De Giorgio, R, Paolisso, G, Rizzo, M, Borghi, C, Strocchi, E, Ianniello, E, Soldati, M, Sabba, C, Vella, F, Suppressa, P, Schilardi, A, Loparco, F, De Vincenzo, G, Comitangelo, A, Amoruso, E, Fenoglio, L, Falcetta, A, Bracco, C, Fracanzani Silvia Fargion, A, Tiraboschi, S, Cespiati, A, Oberti, G, Sigon, G, Peyvandi, F, Rossio, R, Ferrari, B, Colombo, G, Agosti, P, Monzani, V, Savojardo, V, Folli, C, Ceriani, G, Pallini, G, Dallegri, F, Ottonello, L, Liberale, L, Caserza, L, Salam, K, Liberato, N, Tognin, T, Bianchi, G, Giaquinto, S, Purrello, F, Di Pino, A, Piro, S, Rozzini, R, Falanga, L, Spazzini, E, Ferrandina, C, Montrucchio, G, Petitti, P, Peasso, P, Favale, E, Poletto, C, Salmi, R, Gaudenzi, P, Perri, L, Landolfi, R, Montalto, M, Mirijello, A, Guasti, L, Castiglioni, L, Maresca, A, Squizzato, A, Campiotti, L, Grossi, A, Bertolotti, M, Mussi, C, Lancellotti, G, Libbra, M, Dondi, G, Pellegrini, E, Carulli, L, Galassi, M, Grassi, Y, Perticone, M, Battaglia, R, Filice, M, Maio, R, Stanghellini, V, Ruggeri, E, del Vecchio, S, Salvi, A, Leonardi, R, Damiani, G, Capeci, W, Gabrielli, A, Mattioli, M, Martino, G, Biondi, L, Pettinari, P, Ghio, R, Col, A, Minisola, S, Colangelo, L, Cilli, M, Labbadia, G, Afeltra, A, Marigliano, B, Pipita, M, Castellino, P, Zanoli, L, Pignataro, S, Gennaro, A, Blanco, J, Saracco, V, Fogliati, M, Bussolino, C, Mete, F, Gino, M, Cittadini, A, Vigorito, C, Arcopinto, M, Salzano, A, Bobbio, E, Sirico, D, Moreo, G, Gasparini, F, Prolo, S, Pina, G, Ballestrero, A, Ferrando, F, Berra, S, Dassi, S, Nava, M, Graziella, B, Baldassarre, S, Fragapani, S, Gruden, G, Galanti, G, Mascherini, G, Petri, C, Stefani, L, Girino, M, Piccinelli, V, Nasso, F, Gioffre, V, Pasquale, M, Scattolin, G, Martinelli, S, Turrin, M, Sechi, L, Catena, C, Colussi, G, Passariello, N, Rinaldi, L, Berti, F, Famularo, G, Tarsitani, P, Castello, R, Pasino, M, Ceda, G, Maggio, M, Morganti, S, Artoni, A, Del Giacco, S, Firinu, D, Losa, F, Paoletti, G, Costanzo, G, Montalto, G, Licata, A, Malerba, V, Montalto, F, Lasco, A, Basile, G, Catalano, A, Malatino, L, Stancanelli, B, Terranova, V, Di Marca, S, Di Quattro, R, La Malfa, L, Caruso, R, Mecocci, P, Ruggiero, C, Boccardi, V, Meschi, T, Lauretani, F, Ticinesi, A, Nouvenne, A, Minuz, P, Fondrieschi, L, Pirisi, M, Fra, G, Sola, D, Porta, M, Riva, P, Quadri, R, Larovere, E, Novelli, M, Scanzi, G, Mengoli, C, Provini, S, Ricevuti, L, Simeone, E, Scurti, R, Tolloso, F, Tarquini, R, Valoriani, A, Dolenti, S, Vannini, G, Tedeschi, A, Trotta, L, Volpi, R, Bocchi, P, Vignali, A, Harari, S, Lonati, C, Cattaneo, M, Napoli, F, Argano C., Scichilone N., Natoli G., Nobili A., Corazza G. R., Mannucci P. M., Perticone F., Corrao S., Pietrangelo A., Licata G., Violi F., Marengoni A., Salerno F., Cesari M., Tettamanti M., Pasina L., Franchi C., Miglio G., Cortesi L., Ardoino I., Novella A., Prisco D., Silvestri E., Emmi G., Bettiol A., Caterina C., Biolo G., Zanetti M., Guadagni M., Zaccari M., Chiuch M., Vanoli M., Grignani G., Pulixi E. A., Bernardi M., Bassi S. L., Santi L., Zaccherini G., Lupattelli G., Mannarino E., Bianconi V., Paciullo F., Alcidi R., Nuti R., Valenti R., Ruvio M., Cappelli S., Palazzuoli A., Girelli D., Busti F., Marchi G., Barbagallo M., Dominguez L., Cocita F., Beneduce V., Plances L., Mularo S., Raspanti M., Cavallaro F., Zoli M., Lazzari I., Brunori M., Fabbri E., Magalotti D., Arno R., Pasini F. L., Capecchi P. L., Palasciano G., Modeo M. E., Di Gennaro C., Cappellini M. D., Maira D., Di Stefano V., Fabio G., Seghezzi S., Mancarella M., De Amicis M. M., De Luca G., Scaramellini N., Rossi P. D., Damanti S., Clerici M., Conti F., Bonini G., Ottolini B. B., Di Sabatino A., Miceli E., Lenti M. V., Pisati M., Dominioni C. C., Murialdo G., Marra A., Cattaneo F., Pontremoli R., Beccati V., Nobili G., Secchi M. B., Ghelfi D., Anastasio L., Sofia L., Carbone M., Cipollone F., Guagnano M. T., Valeriani E., Rossi I., Mancuso G., Calipari D., Bartone M., Delitala G., Berria M., Pes C., Delitala A., Muscaritoli M., Molfino A., Petrillo E., Zuccala G., D'Aurizio G., Romanelli G., Zucchelli A., Manzoni F., Volpini A., Picardi A., Gentilucci U. V., Gallo P., Dell'Unto C., Annoni G., Corsi M., Bellelli G., Zazzetta S., Mazzola P., Szabo H., Bonfanti A., Arturi F., Succurro E., Rubino M., Tassone B., Sesti G., Serra M. G., Bleve M. A., Gasbarrone L., Sajeva M. R., Brucato A., Ghidoni S., Fabris F., Bertozzi I., Bogoni G., Rabuini M. V., Cosi E., Scarinzi P., Amabile A., Omenetto E., Prandini T., Manfredini R., Fabbian F., Boari B., De Giorgi A., Tiseo R., De Giorgio R., Paolisso G., Rizzo M. R., Borghi C., Strocchi E., Ianniello E., Soldati M., Sabba C., Vella F. S., Suppressa P., Schilardi A., Loparco F., De Vincenzo G. M., Comitangelo A., Amoruso E., Fenoglio L., Falcetta A., Bracco C., Fracanzani Silvia Fargion A. L., Tiraboschi S., Cespiati A., Oberti G., Sigon G., Peyvandi F., Rossio R., Ferrari B., Colombo G., Agosti P., Monzani V., Savojardo V., Folli C., Ceriani G., Pallini G., Dallegri F., Ottonello L., Liberale L., Caserza L., Salam K., Liberato N. L., Tognin T., Bianchi G. B., Giaquinto S., Purrello F., Di Pino A., Piro S., Rozzini R., Falanga L., Spazzini E., Ferrandina C., Montrucchio G., Petitti P., Peasso P., Favale E., Poletto C., Salmi R., Gaudenzi P., Perri L., Landolfi R., Montalto M., Mirijello A., Guasti L., Castiglioni L., Maresca A., Squizzato A., Campiotti L., Grossi A., Bertolotti M., Mussi C., Lancellotti G., Libbra M. V., Dondi G., Pellegrini E., Carulli L., Galassi M., Grassi Y., Perticone M., Battaglia R., FIlice M., Maio R., Stanghellini V., Ruggeri E., del Vecchio S., Salvi A., Leonardi R., Damiani G., Capeci W., Gabrielli A., Mattioli M., Martino G. P., Biondi L., Pettinari P., Ghio R., Col A. D., Minisola S., Colangelo L., Cilli M., Labbadia G., Afeltra A., Marigliano B., Pipita M. E., Castellino P., Zanoli L., Pignataro S., Gennaro A., Blanco J., Saracco V., Fogliati M., Bussolino C., Mete F., Gino M., Cittadini A., Vigorito C., Arcopinto M., Salzano A., Bobbio E., Marra A. M., Sirico D., Moreo G., Gasparini F., Prolo S., Pina G., Ballestrero A., Ferrando F., Berra S., Dassi S., Nava M. C., Graziella B., Baldassarre S., Fragapani S., Gruden G., Galanti G., Mascherini G., Petri C., Stefani L., Girino M., Piccinelli V., Nasso F., Gioffre V., Pasquale M., Scattolin G., Martinelli S., Turrin M., Sechi L., Catena C., Colussi G., Passariello N., Rinaldi L., Berti F., Famularo G., Tarsitani P., Castello R., Pasino M., Ceda G. P., Maggio M. G., Morganti S., Artoni A., Del Giacco S., Firinu D., Losa F., Paoletti G., Costanzo G., Montalto G., Licata A., Malerba V., Montalto F. A., Lasco A., Basile G., Catalano A., Malatino L., Stancanelli B., Terranova V., Di Marca S., Di Quattro R., La Malfa L., Caruso R., Mecocci P., Ruggiero C., Boccardi V., Meschi T., Lauretani F., Ticinesi A., Nouvenne A., Minuz P., Fondrieschi L., Pirisi M., Fra G. P., Sola D., Porta M., Riva P., Quadri R., Larovere E., Novelli M., Scanzi G., Mengoli C., Provini S., Ricevuti L., Simeone E., Scurti R., Tolloso F., Tarquini R., Valoriani A., Dolenti S., Vannini G., Tedeschi A., Trotta L., Volpi R., Bocchi P., Vignali A., Harari S., Lonati C., Cattaneo M., and Napoli F.
Abstract: Currently, chronic obstructive pulmonary disease (COPD) represents the fourth cause of death worldwide with significant economic burden. Comorbidities increase in number and severity with age and are identified as important determinants that influence the prognosis. In this observational study, we retrospectively analyzed data collected from the RePoSI register. We aimed to investigate comorbidities and outcomes in a cohort of hospitalized elderly patients with the clinical diagnosis of COPD. Socio-demographic, clinical characteristics and laboratory findings were considered. The association between variables and in-hospital, 3-month and 1-year follow-up were analyzed. Among 4696 in-patients, 932 (19.8%) had a diagnosis of COPD. Patients with COPD had more hospitalization, a significant overt cognitive impairment, a clinically significant disability and more depression in comparison with non-COPD subjects. COPD patients took more drugs, both at admission, in-hospital stay, discharge and 3-month and 1-year follow-up. 14 comorbidities were more frequent in COPD patients. Cerebrovascular disease was an independent predictor of in-hospital mortality. At 3-month follow-up, male sex and hepatic cirrhosis were independently associated with mortality. ICS-LABA therapy was predictor of mortality at in-hospital, 3-month and 1-year follow-up. This analysis showed the severity of impact of COPD and its comorbidities in the real life of internal medicine and geriatric wards.
Published: 2021

42. Hyperglycemia at admission, comorbidities, and in-hospital mortality in elderly patients hospitalized in internal medicine wards: data from the RePoSI Registry

Author: Corrao, S, Nobili, A, Natoli, G, Mannucci, P, Perticone, F, Pietrangelo, A, Argano, C, Licata, G, Violi, F, Corazza, G, Marengoni, A, Salerno, F, Cesari, M, Tettamanti, M, Pasina, L, Franchi, C, Cortesi, L, Miglio, G, Ardoino, I, Novella, A, Prisco, D, Silvestri, E, Emmi, G, Bettiol, A, Caterina, C, Biolo, G, Zanetti, M, Guadagni, M, Zaccari, M, Chiuch, M, Vanoli, M, Grignani, G, Pulixi, E, Bernardi, M, Bassi, S, Santi, L, Zaccherini, G, Lupattelli, G, Mannarino, E, Bianconi, V, Paciullo, F, Alcidi, R, Nuti, R, Valenti, R, Ruvio, M, Cappelli, S, Palazzuoli, A, Girelli, D, Busti, F, Marchi, G, Barbagallo, M, Dominguez, L, Cocita, F, Beneduce, V, Plances, L, Mularo, S, Raspanti, M, Zoli, M, Lazzari, I, Brunori, M, Fabbri, E, Magalotti, D, Arno, R, Pasini, F, Capecchi, P, Palasciano, G, Modeo, M, Di Gennaro, C, Cappellini, M, Maira, D, Di Stefano, V, Fabio, G, Seghezzi, S, Mancarella, M, De Amicis, M, De Luca, G, Scaramellini, N, Rossi, P, Damanti, S, Clerici, M, Conti, F, Bonini, G, Ottolini, B, Di Sabatino, A, Miceli, E, Lenti, M, Pisati, M, Dominioni, C, Murialdo, G, Marra, A, Cattaneo, F, Pontremoli, R, Beccati, V, Nobili, G, Secchi, M, Ghelfi, D, Anastasio, L, Sofia, L, Carbone, M, Cipollone, F, Guagnano, M, Valeriani, E, Rossi, I, Mancuso, G, Calipari, D, Bartone, M, Delitala, G, Berria, M, Pes, C, Delitala, A, Muscaritoli, M, Molfino, A, Petrillo, E, Zuccala, G, D'Aurizio, G, Romanelli, G, Zucchelli, A, Manzoni, F, Volpini, A, Picardi, A, Gentilucci, U, Gallo, P, Dell'Unto, C, Annoni, G, Corsi, M, Bellelli, G, Zazzetta, S, Mazzola, P, Szabo, H, Bonfanti, A, Arturi, F, Succurro, E, Rubino, M, Tassone, B, Sesti, G, Serra, M, Bleve, M, Gasbarrone, L, Sajeva, M, Brucato, A, Ghidoni, S, Fabris, F, Bertozzi, I, Bogoni, G, Rabuini, M, Cosi, E, Scarinzi, P, Amabile, A, Omenetto, E, Prandini, T, Manfredini, R, Fabbian, F, Boari, B, De Giorgi, A, Tiseo, R, De Giorgio, R, Paolisso, G, Rizzo, M, Borghi, C, Strocchi, E, Ianniello, E, Soldati, M, Sabba, C, Vella, F, Suppressa, P, Schilardi, A, Loparco, F, De Vincenzo, G, Comitangelo, A, Amoruso, E, Fenoglio, L, Falcetta, A, Bracco, C, Fargion, A, Tiraboschi, S, Cespiati, A, Oberti, G, Sigon, G, Peyvandi, F, Rossio, R, Ferrari, B, Colombo, G, Agosti, P, Monzani, V, Savojardo, V, Folli, C, Ceriani, G, Pallini, G, Dallegri, F, Ottonello, L, Liberale, L, Caserza, L, Salam, K, Liberato, N, Tognin, T, Bianchi, G, Giaquinto, S, Purrello, F, Di Pino, A, Piro, S, Rozzini, R, Falanga, L, Spazzini, E, Ferrandina, C, Montrucchio, G, Petitti, P, Peasso, P, Favale, E, Poletto, C, Salmi, R, Gaudenzi, P, Perri, L, Landolfi, R, Montalto, M, Mirijello, A, Guasti, L, Castiglioni, L, Maresca, A, Squizzato, A, Campiotti, L, Grossi, A, Bertolotti, M, Mussi, C, Lancellotti, G, Libbra, M, Dondi, G, Pellegrini, E, Carulli, L, Galassi, M, Grassi, Y, Perticone, M, Battaglia, R, Filice, M, Maio, R, Stanghellini, V, Ruggeri, E, del Vecchio, S, Salvi, A, Leonardi, R, Damiani, G, Capeci, W, Gabrielli, A, Mattioli, M, Martino, G, Biondi, L, Pettinari, P, Ghio, R, Col, A, Minisola, S, Colangelo, L, Cilli, M, Labbadia, G, Afeltra, A, Marigliano, B, Pipita, M, Castellino, P, Zanoli, L, Pignataro, S, Gennaro, A, Blanco, J, Saracco, V, Fogliati, M, Bussolino, C, Mete, F, Gino, M, Cittadini, A, Vigorito, C, Arcopinto, M, Salzano, A, Bobbio, E, Sirico, D, Moreo, G, Gasparini, F, Prolo, S, Pina, G, Ballestrero, A, Ferrando, F, Berra, S, Dassi, S, Nava, M, Graziella, B, Baldassarre, S, Fragapani, S, Gruden, G, Galanti, G, Mascherini, G, Petri, C, Stefani, L, Girino, M, Piccinelli, V, Nasso, F, Gioffre, V, Pasquale, M, Scattolin, G, Martinelli, S, Turrin, M, Sechi, L, Catena, C, Colussi, G, Passariello, N, Rinaldi, L, Berti, F, Famularo, G, Tarsitani, P, Castello, R, Pasino, M, Ceda, G, Maggio, M, Morganti, S, Artoni, A, Del Giacco, S, Firinu, D, Losa, F, Paoletti, G, Costanzo, G, Montalto, G, Licata, A, Malerba, V, Montalto, F, Lasco, A, Basile, G, Catalano, A, Malatino, L, Stancanelli, B, Terranova, V, Di Marca, S, Di Quattro, R, La Malfa, L, Caruso, R, Mecocci, P, Ruggiero, C, Boccardi, V, Meschi, T, Lauretani, F, Ticinesi, A, Nouvenne, A, Minuz, P, Fondrieschi, L, Pirisi, M, Fra, G, Sola, D, Porta, M, Riva, P, Quadri, R, Larovere, E, Novelli, M, Scanzi, G, Mengoli, C, Provini, S, Ricevuti, L, Simeone, E, Scurti, R, Tolloso, F, Tarquini, R, Valoriani, A, Dolenti, S, Vannini, G, Tedeschi, A, Trotta, L, Volpi, R, Bocchi, P, Vignali, A, Harari, S, Lonati, C, Cattaneo, M, Napoli, F, Corrao S., Nobili A., Natoli G., Mannucci P. M., Perticone F., Pietrangelo A., Argano C., Licata G., Violi F., Corazza G. R., Marengoni A., Salerno F., Cesari M., Tettamanti M., Pasina L., Franchi C., Cortesi L., Miglio G., Ardoino I., Novella A., Prisco D., Silvestri E., Emmi G., Bettiol A., Caterina C., Biolo G., Zanetti M., Guadagni M., Zaccari M., Chiuch M., Vanoli M., Grignani G., Pulixi E. A., Bernardi M., Bassi S. L., Santi L., Zaccherini G., Lupattelli G., Mannarino E., Bianconi V., Paciullo F., Alcidi R., Nuti R., Valenti R., Ruvio M., Cappelli S., Palazzuoli A., Girelli D., Busti F., Marchi G., Barbagallo M., Dominguez L., Cocita F., Beneduce V., Plances L., Mularo S., Raspanti M., Zoli M., Lazzari I., Brunori M., Fabbri E., Magalotti D., Arno R., Pasini F. L., Capecchi P. L., Palasciano G., Modeo M. E., Di Gennaro C., Cappellini M. D., Maira D., Di Stefano V., Fabio G., Seghezzi S., Mancarella M., De Amicis M. M., De Luca G., Scaramellini N., Rossi P. D., Damanti S., Clerici M., Conti F., Bonini G., Ottolini B. B., Di Sabatino A., Miceli E., Lenti M. V., Pisati M., Dominioni C. C., Murialdo G., Marra A., Cattaneo F., Pontremoli R., Beccati V., Nobili G., Secchi M. B., Ghelfi D., Anastasio L., Sofia L., Carbone M., Cipollone F., Guagnano M. T., Valeriani E., Rossi I., Mancuso G., Calipari D., Bartone M., Delitala G., Berria M., Pes C., Delitala A., Muscaritoli M., Molfino A., Petrillo E., Zuccala G., D'Aurizio G., Romanelli G., Zucchelli A., Manzoni F., Volpini A., Picardi A., Gentilucci U. V., Gallo P., Dell'Unto C., Annoni G., Corsi M., Bellelli G., Zazzetta S., Mazzola P., Szabo H., Bonfanti A., Arturi F., Succurro E., Rubino M., Tassone B., Sesti G., Serra M. G., Bleve M. A., Gasbarrone L., Sajeva M. R., Brucato A., Ghidoni S., Fabris F., Bertozzi I., Bogoni G., Rabuini M. V., Cosi E., Scarinzi P., Amabile A., Omenetto E., Prandini T., Manfredini R., Fabbian F., Boari B., De Giorgi A., Tiseo R., De Giorgio R., Paolisso G., Rizzo M. R., Borghi C., Strocchi E., Ianniello E., Soldati M., Sabba C., Vella F. S., Suppressa P., Schilardi A., Loparco F., De Vincenzo G. M., Comitangelo A., Amoruso E., Fenoglio L., Falcetta A., Bracco C., Fargion A. L. F. S., Tiraboschi S., Cespiati A., Oberti G., Sigon G., Peyvandi F., Rossio R., Ferrari B., Colombo G., Agosti P., Monzani V., Savojardo V., Folli C., Ceriani G., Pallini G., Dallegri F., Ottonello L., Liberale L., Caserza L., Salam K., Liberato N. L., Tognin T., Bianchi G. B., Giaquinto S., Purrello F., Di Pino A., Piro S., Rozzini R., Falanga L., Spazzini E., Ferrandina C., Montrucchio G., Petitti P., Peasso P., Favale E., Poletto C., Salmi R., Gaudenzi P., Perri L., Landolfi R., Montalto M., Mirijello A., Guasti L., Castiglioni L., Maresca A., Squizzato A., Campiotti L., Grossi A., Bertolotti M., Mussi C., Lancellotti G., Libbra M. V., Dondi G., Pellegrini E., Carulli L., Galassi M., Grassi Y., Perticone M., Battaglia R., FIlice M., Maio R., Stanghellini V., Ruggeri E., del Vecchio S., Salvi A., Leonardi R., Damiani G., Capeci W., Gabrielli A., Mattioli M., Martino G. P., Biondi L., Pettinari P., Ghio R., Col A. D., Minisola S., Colangelo L., Cilli M., Labbadia G., Afeltra A., Marigliano B., Pipita M. E., Castellino P., Zanoli L., Pignataro S., Gennaro A., Blanco J., Saracco V., Fogliati M., Bussolino C., Mete F., Gino M., Cittadini A., Vigorito C., Arcopinto M., Salzano A., Bobbio E., Marra A. M., Sirico D., Moreo G., Gasparini F., Prolo S., Pina G., Ballestrero A., Ferrando F., Berra S., Dassi S., Nava M. C., Graziella B., Baldassarre S., Fragapani S., Gruden G., Galanti G., Mascherini G., Petri C., Stefani L., Girino M., Piccinelli V., Nasso F., Gioffre V., Pasquale M., Scattolin G., Martinelli S., Turrin M., Sechi L., Catena C., Colussi G., Passariello N., Rinaldi L., Berti F., Famularo G., Tarsitani P., Castello R., Pasino M., Ceda G. P., Maggio M. G., Morganti S., Artoni A., Del Giacco S., Firinu D., Losa F., Paoletti G., Costanzo G., Montalto G., Licata A., Malerba V., Montalto F. A., Lasco A., Basile G., Catalano A., Malatino L., Stancanelli B., Terranova V., Di Marca S., Di Quattro R., La Malfa L., Caruso R., Mecocci P., Ruggiero C., Boccardi V., Meschi T., Lauretani F., Ticinesi A., Nouvenne A., Minuz P., Fondrieschi L., Pirisi M., Fra G. P., Sola D., Porta M., Riva P., Quadri R., Larovere E., Novelli M., Scanzi G., Mengoli C., Provini S., Ricevuti L., Simeone E., Scurti R., Tolloso F., Tarquini R., Valoriani A., Dolenti S., Vannini G., Tedeschi A., Trotta L., Volpi R., Bocchi P., Vignali A., Harari S., Lonati C., Cattaneo M., Napoli F., Corrao, S, Nobili, A, Natoli, G, Mannucci, P, Perticone, F, Pietrangelo, A, Argano, C, Licata, G, Violi, F, Corazza, G, Marengoni, A, Salerno, F, Cesari, M, Tettamanti, M, Pasina, L, Franchi, C, Cortesi, L, Miglio, G, Ardoino, I, Novella, A, Prisco, D, Silvestri, E, Emmi, G, Bettiol, A, Caterina, C, Biolo, G, Zanetti, M, Guadagni, M, Zaccari, M, Chiuch, M, Vanoli, M, Grignani, G, Pulixi, E, Bernardi, M, Bassi, S, Santi, L, Zaccherini, G, Lupattelli, G, Mannarino, E, Bianconi, V, Paciullo, F, Alcidi, R, Nuti, R, Valenti, R, Ruvio, M, Cappelli, S, Palazzuoli, A, Girelli, D, Busti, F, Marchi, G, Barbagallo, M, Dominguez, L, Cocita, F, Beneduce, V, Plances, L, Mularo, S, Raspanti, M, Zoli, M, Lazzari, I, Brunori, M, Fabbri, E, Magalotti, D, Arno, R, Pasini, F, Capecchi, P, Palasciano, G, Modeo, M, Di Gennaro, C, Cappellini, M, Maira, D, Di Stefano, V, Fabio, G, Seghezzi, S, Mancarella, M, De Amicis, M, De Luca, G, Scaramellini, N, Rossi, P, Damanti, S, Clerici, M, Conti, F, Bonini, G, Ottolini, B, Di Sabatino, A, Miceli, E, Lenti, M, Pisati, M, Dominioni, C, Murialdo, G, Marra, A, Cattaneo, F, Pontremoli, R, Beccati, V, Nobili, G, Secchi, M, Ghelfi, D, Anastasio, L, Sofia, L, Carbone, M, Cipollone, F, Guagnano, M, Valeriani, E, Rossi, I, Mancuso, G, Calipari, D, Bartone, M, Delitala, G, Berria, M, Pes, C, Delitala, A, Muscaritoli, M, Molfino, A, Petrillo, E, Zuccala, G, D'Aurizio, G, Romanelli, G, Zucchelli, A, Manzoni, F, Volpini, A, Picardi, A, Gentilucci, U, Gallo, P, Dell'Unto, C, Annoni, G, Corsi, M, Bellelli, G, Zazzetta, S, Mazzola, P, Szabo, H, Bonfanti, A, Arturi, F, Succurro, E, Rubino, M, Tassone, B, Sesti, G, Serra, M, Bleve, M, Gasbarrone, L, Sajeva, M, Brucato, A, Ghidoni, S, Fabris, F, Bertozzi, I, Bogoni, G, Rabuini, M, Cosi, E, Scarinzi, P, Amabile, A, Omenetto, E, Prandini, T, Manfredini, R, Fabbian, F, Boari, B, De Giorgi, A, Tiseo, R, De Giorgio, R, Paolisso, G, Rizzo, M, Borghi, C, Strocchi, E, Ianniello, E, Soldati, M, Sabba, C, Vella, F, Suppressa, P, Schilardi, A, Loparco, F, De Vincenzo, G, Comitangelo, A, Amoruso, E, Fenoglio, L, Falcetta, A, Bracco, C, Fargion, A, Tiraboschi, S, Cespiati, A, Oberti, G, Sigon, G, Peyvandi, F, Rossio, R, Ferrari, B, Colombo, G, Agosti, P, Monzani, V, Savojardo, V, Folli, C, Ceriani, G, Pallini, G, Dallegri, F, Ottonello, L, Liberale, L, Caserza, L, Salam, K, Liberato, N, Tognin, T, Bianchi, G, Giaquinto, S, Purrello, F, Di Pino, A, Piro, S, Rozzini, R, Falanga, L, Spazzini, E, Ferrandina, C, Montrucchio, G, Petitti, P, Peasso, P, Favale, E, Poletto, C, Salmi, R, Gaudenzi, P, Perri, L, Landolfi, R, Montalto, M, Mirijello, A, Guasti, L, Castiglioni, L, Maresca, A, Squizzato, A, Campiotti, L, Grossi, A, Bertolotti, M, Mussi, C, Lancellotti, G, Libbra, M, Dondi, G, Pellegrini, E, Carulli, L, Galassi, M, Grassi, Y, Perticone, M, Battaglia, R, Filice, M, Maio, R, Stanghellini, V, Ruggeri, E, del Vecchio, S, Salvi, A, Leonardi, R, Damiani, G, Capeci, W, Gabrielli, A, Mattioli, M, Martino, G, Biondi, L, Pettinari, P, Ghio, R, Col, A, Minisola, S, Colangelo, L, Cilli, M, Labbadia, G, Afeltra, A, Marigliano, B, Pipita, M, Castellino, P, Zanoli, L, Pignataro, S, Gennaro, A, Blanco, J, Saracco, V, Fogliati, M, Bussolino, C, Mete, F, Gino, M, Cittadini, A, Vigorito, C, Arcopinto, M, Salzano, A, Bobbio, E, Sirico, D, Moreo, G, Gasparini, F, Prolo, S, Pina, G, Ballestrero, A, Ferrando, F, Berra, S, Dassi, S, Nava, M, Graziella, B, Baldassarre, S, Fragapani, S, Gruden, G, Galanti, G, Mascherini, G, Petri, C, Stefani, L, Girino, M, Piccinelli, V, Nasso, F, Gioffre, V, Pasquale, M, Scattolin, G, Martinelli, S, Turrin, M, Sechi, L, Catena, C, Colussi, G, Passariello, N, Rinaldi, L, Berti, F, Famularo, G, Tarsitani, P, Castello, R, Pasino, M, Ceda, G, Maggio, M, Morganti, S, Artoni, A, Del Giacco, S, Firinu, D, Losa, F, Paoletti, G, Costanzo, G, Montalto, G, Licata, A, Malerba, V, Montalto, F, Lasco, A, Basile, G, Catalano, A, Malatino, L, Stancanelli, B, Terranova, V, Di Marca, S, Di Quattro, R, La Malfa, L, Caruso, R, Mecocci, P, Ruggiero, C, Boccardi, V, Meschi, T, Lauretani, F, Ticinesi, A, Nouvenne, A, Minuz, P, Fondrieschi, L, Pirisi, M, Fra, G, Sola, D, Porta, M, Riva, P, Quadri, R, Larovere, E, Novelli, M, Scanzi, G, Mengoli, C, Provini, S, Ricevuti, L, Simeone, E, Scurti, R, Tolloso, F, Tarquini, R, Valoriani, A, Dolenti, S, Vannini, G, Tedeschi, A, Trotta, L, Volpi, R, Bocchi, P, Vignali, A, Harari, S, Lonati, C, Cattaneo, M, Napoli, F, Corrao S., Nobili A., Natoli G., Mannucci P. M., Perticone F., Pietrangelo A., Argano C., Licata G., Violi F., Corazza G. R., Marengoni A., Salerno F., Cesari M., Tettamanti M., Pasina L., Franchi C., Cortesi L., Miglio G., Ardoino I., Novella A., Prisco D., Silvestri E., Emmi G., Bettiol A., Caterina C., Biolo G., Zanetti M., Guadagni M., Zaccari M., Chiuch M., Vanoli M., Grignani G., Pulixi E. A., Bernardi M., Bassi S. L., Santi L., Zaccherini G., Lupattelli G., Mannarino E., Bianconi V., Paciullo F., Alcidi R., Nuti R., Valenti R., Ruvio M., Cappelli S., Palazzuoli A., Girelli D., Busti F., Marchi G., Barbagallo M., Dominguez L., Cocita F., Beneduce V., Plances L., Mularo S., Raspanti M., Zoli M., Lazzari I., Brunori M., Fabbri E., Magalotti D., Arno R., Pasini F. L., Capecchi P. L., Palasciano G., Modeo M. E., Di Gennaro C., Cappellini M. D., Maira D., Di Stefano V., Fabio G., Seghezzi S., Mancarella M., De Amicis M. M., De Luca G., Scaramellini N., Rossi P. D., Damanti S., Clerici M., Conti F., Bonini G., Ottolini B. B., Di Sabatino A., Miceli E., Lenti M. V., Pisati M., Dominioni C. C., Murialdo G., Marra A., Cattaneo F., Pontremoli R., Beccati V., Nobili G., Secchi M. B., Ghelfi D., Anastasio L., Sofia L., Carbone M., Cipollone F., Guagnano M. T., Valeriani E., Rossi I., Mancuso G., Calipari D., Bartone M., Delitala G., Berria M., Pes C., Delitala A., Muscaritoli M., Molfino A., Petrillo E., Zuccala G., D'Aurizio G., Romanelli G., Zucchelli A., Manzoni F., Volpini A., Picardi A., Gentilucci U. V., Gallo P., Dell'Unto C., Annoni G., Corsi M., Bellelli G., Zazzetta S., Mazzola P., Szabo H., Bonfanti A., Arturi F., Succurro E., Rubino M., Tassone B., Sesti G., Serra M. G., Bleve M. A., Gasbarrone L., Sajeva M. R., Brucato A., Ghidoni S., Fabris F., Bertozzi I., Bogoni G., Rabuini M. V., Cosi E., Scarinzi P., Amabile A., Omenetto E., Prandini T., Manfredini R., Fabbian F., Boari B., De Giorgi A., Tiseo R., De Giorgio R., Paolisso G., Rizzo M. R., Borghi C., Strocchi E., Ianniello E., Soldati M., Sabba C., Vella F. S., Suppressa P., Schilardi A., Loparco F., De Vincenzo G. M., Comitangelo A., Amoruso E., Fenoglio L., Falcetta A., Bracco C., Fargion A. L. F. S., Tiraboschi S., Cespiati A., Oberti G., Sigon G., Peyvandi F., Rossio R., Ferrari B., Colombo G., Agosti P., Monzani V., Savojardo V., Folli C., Ceriani G., Pallini G., Dallegri F., Ottonello L., Liberale L., Caserza L., Salam K., Liberato N. L., Tognin T., Bianchi G. B., Giaquinto S., Purrello F., Di Pino A., Piro S., Rozzini R., Falanga L., Spazzini E., Ferrandina C., Montrucchio G., Petitti P., Peasso P., Favale E., Poletto C., Salmi R., Gaudenzi P., Perri L., Landolfi R., Montalto M., Mirijello A., Guasti L., Castiglioni L., Maresca A., Squizzato A., Campiotti L., Grossi A., Bertolotti M., Mussi C., Lancellotti G., Libbra M. V., Dondi G., Pellegrini E., Carulli L., Galassi M., Grassi Y., Perticone M., Battaglia R., FIlice M., Maio R., Stanghellini V., Ruggeri E., del Vecchio S., Salvi A., Leonardi R., Damiani G., Capeci W., Gabrielli A., Mattioli M., Martino G. P., Biondi L., Pettinari P., Ghio R., Col A. D., Minisola S., Colangelo L., Cilli M., Labbadia G., Afeltra A., Marigliano B., Pipita M. E., Castellino P., Zanoli L., Pignataro S., Gennaro A., Blanco J., Saracco V., Fogliati M., Bussolino C., Mete F., Gino M., Cittadini A., Vigorito C., Arcopinto M., Salzano A., Bobbio E., Marra A. M., Sirico D., Moreo G., Gasparini F., Prolo S., Pina G., Ballestrero A., Ferrando F., Berra S., Dassi S., Nava M. C., Graziella B., Baldassarre S., Fragapani S., Gruden G., Galanti G., Mascherini G., Petri C., Stefani L., Girino M., Piccinelli V., Nasso F., Gioffre V., Pasquale M., Scattolin G., Martinelli S., Turrin M., Sechi L., Catena C., Colussi G., Passariello N., Rinaldi L., Berti F., Famularo G., Tarsitani P., Castello R., Pasino M., Ceda G. P., Maggio M. G., Morganti S., Artoni A., Del Giacco S., Firinu D., Losa F., Paoletti G., Costanzo G., Montalto G., Licata A., Malerba V., Montalto F. A., Lasco A., Basile G., Catalano A., Malatino L., Stancanelli B., Terranova V., Di Marca S., Di Quattro R., La Malfa L., Caruso R., Mecocci P., Ruggiero C., Boccardi V., Meschi T., Lauretani F., Ticinesi A., Nouvenne A., Minuz P., Fondrieschi L., Pirisi M., Fra G. P., Sola D., Porta M., Riva P., Quadri R., Larovere E., Novelli M., Scanzi G., Mengoli C., Provini S., Ricevuti L., Simeone E., Scurti R., Tolloso F., Tarquini R., Valoriani A., Dolenti S., Vannini G., Tedeschi A., Trotta L., Volpi R., Bocchi P., Vignali A., Harari S., Lonati C., Cattaneo M., and Napoli F.
Abstract: Aims: The association between hyperglycemia at hospital admission and relevant short- and long-term outcomes in elderly population is known. We assessed the effects on mortality of hyperglycemia, disability, and multimorbidity at admission in internal medicine ward in patients aged ≥ 65 years. Methods: Data were collected from an active register of 102 internal medicine and geriatric wards in Italy (RePoSi project). Patients were recruited during four index weeks of a year. Socio-demographic data, reason for hospitalization, diagnoses, treatment, severity and comorbidity indexes (Cumulative Illness rating Scale CIRS-SI and CIRS-CI), renal function, functional (Barthel Index), and cognitive status (Short Blessed Test) and mood disorders (Geriatric Depression Scale) were recorded. Mortality rates were assessed in hospital 3 and 12 months after discharge. Results: Of the 4714 elderly patients hospitalized, 361 had a glycemia level ≥ 250 mg/dL at admission. Compared to subjects with lower glycemia level, patients with glycemia ≥ 250 mg/dL showed higher rates of male sex, smoke and class III obesity. These patients had a significantly lower Barthel Index (p = 0.0249), higher CIRS-SI and CIRS-CI scores (p = 0.0025 and p = 0.0013, respectively), and took more drugs. In-hospital mortality rate was 9.2% and 5.1% in subjects with glycemia ≥ 250 and < 250 mg/dL, respectively (p = 0.0010). Regression analysis showed a strong association between in-hospital death and glycemia ≥ 250 mg/dL (OR 2.07; [95% CI 1.34–3.19]), Barthel Index ≤ 40 (3.28[2.44–4.42]), CIRS-SI (1.87[1.27–2.77]), and male sex (1.54[1.16–2.03]). Conclusions: The stronger predictors of in-hospital mortality for older patients admitted in general wards were glycemia level ≥ 250 mg/dL, Barthel Index ≤ 40, CIRS-SI, and male sex.
Published: 2021

43. Choline-containing compounds quantification by 1H NMR spectroscopy using external reference and noise measurements

Author: Mazzetti, S., Bracco, C., Regge, D., Caivano, R., Russo, F., and Stasi, M.
Published: 2013
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44. Had the Planet Mars Not Existed: Kepler's Equant Model and Its Physical Consequences

Author: Bracco, C. and Provost, J.P
Abstract: We examine the equant model for the motion of planets, which was the starting point of Kepler's investigations before he modified it because of Mars observations. We show that, up to first order in eccentricity, this model implies for each orbit a velocity, which satisfies Kepler's second law and Hamilton's hodograph, and a centripetal acceleration with an r[superscript -2] dependence on the distance to the Sun. If this dependence is assumed to be universal, Kepler's third law follows immediately. This elementary exercise in kinematics for undergraduates emphasizes the proximity of the equant model coming from ancient Greece with our present knowledge. It adds to its historical interest a didactical relevance concerning, in particular, the discussion of the Aristotelian or Newtonian conception of motion. (Contains 3 figures and 15 footnotes.)
Published: 2009
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45. A Simple Derivation of Kepler's Laws without Solving Differential Equations

Author: Provost, J.-P and Bracco, C.
Abstract: Proceeding like Newton with a discrete time approach of motion and a geometrical representation of velocity and acceleration, we obtain Kepler's laws without solving differential equations. The difficult part of Newton's work, when it calls for non-trivial properties of ellipses, is avoided by the introduction of polar coordinates. Then a simple reconsideration of Newton's figure naturally leads to an explicit expression of the velocity and to the equation of the trajectory. This derivation, which can be fully apprehended by undergraduates or by secondary school teachers (who might use it with their pupils), can be considered as a first application of mechanical concepts to a physical problem of great historical and pedagogical interest. (Contains 11 footnotes and 1 figure.)
Published: 2009
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46. The stripping foil test stand in the Linac4 transfer line

Author: Weterings, W., Bracco, C., Noulibos, R., Sillanoli, Y., and van Trappen, P.
Published: 2015
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47. Feasibility of crystal-assisted collimation in the CERN accelerator complex

Author: Scandale, W., primary, Arduini, G., additional, Assmann, R., additional, Bracco, C., additional, Butcher, M., additional, Cerutti, F., additional, D’Andrea, M., additional, Esposito, L. S., additional, Garattini, M., additional, Gilardoni, S., additional, Laface, E., additional, Lari, L., additional, Losito, R., additional, Masi, A., additional, Metral, E., additional, Mirarchi, D., additional, Montesano, S., additional, Petrucci, S., additional, Previtali, V., additional, Redaelli, S., additional, Rossi, R., additional, Schoofs, P., additional, Silari, M., additional, Tlustos, L., additional, Burmistrov, L., additional, Natochii, A., additional, Dubos, S., additional, Puill, V., additional, Stocchi, A., additional, Bagli, E., additional, Bandiera, L., additional, Baricordi, E., additional, Dalpiaz, P., additional, Fiorini, M., additional, Guidi, V., additional, Mazzolari, A., additional, Vincenzi, D., additional, Addesa, F., additional, Cavoto, G., additional, Iacoangeli, F., additional, Ludovici, L., additional, Santacesaria, R., additional, Valente, P., additional, Galluccio, F., additional, Vallazza, E., additional, Bolognini, D., additional, Foggetta, L., additional, Hasan, S., additional, Lietti, D., additional, Mascagna, V., additional, Mattera, A., additional, Prest, M., additional, Ambrosi, G., additional, Azzarello, P., additional, Bertucci, B., additional, Ionica, M., additional, Battiston, R., additional, Zuccon, P., additional, Burger, W. J., additional, Carnera, A., additional, Della Mea, G., additional, Lombardi, A., additional, De Salvador, D., additional, Milan, R., additional, Vomiero, A., additional, Claps, G., additional, Dabagov, S., additional, Murtas, F., additional, Kovalenko, A. D., additional, Taratin, A. M., additional, Uzhinskiy, V. V., additional, Smirnov, G. I., additional, Denisov, A. S., additional, Gavrikov, Yu. A., additional, Ivanov, Yu. M., additional, Lapina, L. P., additional, Malyarenko, L. G., additional, Skorobogatov, V. V., additional, Suvorov, V. M., additional, Vavilov, S. A., additional, Afonin, A. G., additional, Chesnokov, Yu. A., additional, Durum, A. A., additional, Maisheev, V. A., additional, Sandomirskij, Yu. E., additional, Yanovich, A. A., additional, Yazynin, I. A., additional, Markiewicz, T., additional, Oriunno, M., additional, Wienands, U., additional, Mokhov, N., additional, Still, D., additional, Auzinger, G., additional, Borg, J., additional, Ferguson, W., additional, Fulcher, J., additional, James, T., additional, Hall, G., additional, Pesaresi, M., additional, Raymond, M., additional, Rose, A., additional, Ryan, M., additional, and Zorba, O., additional
Published: 2022
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48. Feasibility of crystal-assisted collimation in the CERN accelerator complex

Author: Scandale, W., Arduini, G., Assmann, R., Bracco, C., Butcher, M., Cerutti, F., D’Andrea, M., Esposito, L. S., Garattini, M., Gilardoni, S., Laface, E., Lari, L., Losito, R., Masi, A., Metral, E., Mirarchi, D., Montesano, S., Petrucci, S., Previtali, V., Redaelli, S., Rossi, R., Schoofs, P., Silari, M., Tlustos, L., Burmistrov, L., Natochii, A., Dubos, S., Puill, V., Stocchi, A., Bagli, E., Bandiera, L., Baricordi, E., Dalpiaz, P., Fiorini, M., Guidi, V., Mazzolari, A., Vincenzi, D., Addesa, F., Cavoto, G., Iacoangeli, F., Ludovici, L., Santacesaria, R., Valente, P., Galluccio, F., Vallazza, E., Bolognini, D., Foggetta, L., Hasan, S., Lietti, D., Mascagna, V., Mattera, A., Prest, M., Ambrosi, G., Azzarello, P., Bertucci, B., Ionica, M., Battiston, R., Zuccon, P., Burger, W. J., Carnera, A., Della Mea, G., Lombardi, A., De Salvador, D., Milan, R., Vomiero, A., Claps, G., Dabagov, S., Murtas, F., Kovalenko, A. D., Taratin, A. M., Uzhinskiy, V. V., Smirnov, G. I., Denisov, A. S., Gavrikov, Yu. A., Ivanov, Yu. M., Lapina, L. P., Malyarenko, L. G., Skorobogatov, V. V., Suvorov, V. M., Vavilov, S. A., Afonin, A. G., Chesnokov, Yu. A., Durum, A. A., Maisheev, V. A., Sandomirskij, Yu. E., Yanovich, A. A., Yazynin, I. A., Markiewicz, T., Oriunno, M., Wienands, U., Mokhov, N., Still, D., Auzinger, G., Borg, J., Ferguson, W., Fulcher, J., James, T., Hall, G., Pesaresi, M., Raymond, M., Rose, A., Ryan, M., and Zorba, O.
Subjects: Nuclear and High Energy Physics, Charged particle channeling, collimation, Settore ING-IND/22 - Scienza e Tecnologia dei Materiali, Astronomy and Astrophysics, particle accelerators, crystal-assisted collimation, Accelerators and Storage Rings, Atomic and Molecular Physics, and Optics, bent crystal, crystal channeling
Abstract: Bent silicon crystals mounted on high-accuracy angular actuators were installed in the CERN Super Proton Synchrotron (SPS) and extensively tested to assess the feasibility of crystal-assisted collimation in circular hadron colliders. The adopted layout was exploited and regularly upgraded for about a decade by the UA9 Collaboration. The investigations provided the compelling evidence of a strong reduction of beam losses induced by nuclear inelastic interactions in the aligned crystals in comparison with amorphous orientation. A conceptually similar device, installed in the betatron cleaning insertion of CERN Large Hadron Collider (LHC), was operated through the complete acceleration and storage cycle and demonstrated a large reduction of the background leaking from the collimation region and radiated into the cold sections of the accelerator and the experimental detectors. The implemented layout and the relevant results of the beam tests performed in the SPS and in the LHC with stored proton and ion beams are extensively discussed.
Published: 2022

49. Antibiotic use and associated factors in a large sample of hospitalised older people

Author: Ardoino, I, Mannucci, Pm, Nobili, A, Franchi, C, Tettamanti, M, Pasina, L, Corrao, S, Marengoni, A, Salerno, F, Cesari, M, Perticone, F, Licata, G, Violi, F, Corazza, Gr, Prisco, D, Silvestri, E, Emmi, G, Bettiol, A, Caterina, C, Biolo, G, Zanetti, M, Guadagni, M, Zaccari, M, Chiuch, M, Vanoli, M, Grignani, G, Pulixi, Ea, Bernardi, M, Bassi, Sl, Santi, L, Zaccherini, G, Lupattelli, G, Mannarino, E, Bianconi, V, Paciullo, F, Alcidi, R, Nuti, R, Valenti, R, Ruvio, M, Cappelli, S, Palazzuoli, A, Girelli, D, Busti, F, Marchi, G, Barbagallo, M, Dominguez, L, Cocita, F, Beneduce, V, Plances, L, Natoli, G, Mularo, S, Raspanti, M, Cavallaro, F, Zoli, M, Lazzari, I, Brunori, M, Fabbri, E, Magalotti, D, Arn?, R, Pasini, Fl, Capecchi, Pl, Palasciano, G, Modeo, Me, Di Gennaro, C, Cappellini, Md, Maira, D, Di Stefano, V, Fabio, G, Seghezzi, S, Mancarella, M, De Amicis, Mm, De Luca, G, Scaramellini, N, Rossi, Pd, Damanti, S, Clerici, M, Conti, F, Bonini, G, Ottolini, Bb, Di Sabatino, A, Miceli, E, Lenti, Mv, Pisati, M, Dominioni, Cc, Murialdo, G, Marra, A, Cattaneo, F, Pontremoli, R, Beccati, V, Nobili, G, Secchi, Mb, Ghelfi, D, Anastasio, L, Sofia, L, Carbone, M, Cipollone, F, Guagnano, Mt, Valeriani, E, Rossi, I, Mancuso, G, Calipari, D, Bartone, M, Delitala, G, Berria, M, Pes, C, Delitala, A, Muscaritoli, M, Molfino, A, Petrillo, E, Zuccal?, G, D'Aurizio, G, Romanelli, G, Zucchelli, A, Manzoni, F, Volpini, A, Picardi, A, Gentilucci, Uv, Gallo, P, Dell'Unto, C, Annoni, G, Corsi, M, Bellelli, G, Zazzetta, S, Mazzola, P, Szabo, H, Bonfanti, A, Arturi, F, Succurro, E, Rubino, M, Tassone, B, Sesti, G, Serra, Mg, Bleve, Ma, Gasbarrone, L, Sajeva, Mr, Brucato, A, Ghidoni, S, Fabris, F, Bertozzi, I, Bogoni, G, Rabuini, Mv, Cosi, E, Scarinzi, P, Amabile, A, Omenetto, E, Prandini, T, Manfredini, R, Fabbian, F, Boari, B, De Giorgi, A, Tiseo, R, De Giorgio, R, Paolisso, G, Rizzo, Mr, Borghi, C, Strocchi, E, Ianniello, E, Soldati, M, Sabb?, C, Vella, Fs, Suppressa, P, Agosti, P, Schilardi, A, Loparco, F, De Vincenzo, Gm, Comitangelo, A, Amoruso, E, Fenoglio, L, Falcetta, A, Bracco, C, Fracanzani, Al, Fargion, S, Tiraboschi, S, Cespiati, A, Oberti, G, Sigon, G, Peyvandi, F, Rossio, R, Ferrari, B, Colombo, G, Monzani, V, Savojardo, V, Folli, C, Ceriani, G, Pallini, G, Dallegri, F, Ottonello, L, Liberale, L, Caserza, L, Salam, K, Liberato, Nl, Tognin, T, Bianchi, Gb, Giaquinto, S, Purrello, F, Di Pino, A, Piro, S, Rozzini, R, Falanga, L, Spazzini, E, Ferrandina, C, Montrucchio, G, Petitti, P, Peasso, P, Favale, E, Poletto, C, Salmi, R, Gaudenzi, P, Perri, L, Landolfi, R, Montalto, M, Mirijello, A, Guasti, L, Castiglioni, L, Maresca, A, Squizzato, A, Campiotti, L, Grossi, A, Bertolotti, M, Mussi, C, Lancellotti, G, Libbra, Mv, Dondi, G, Pellegrini, E, Carulli, L, Galassi, M, Grassi, Y, Perticone, M, Battaglia, R, Filice, M, Maio, R, Stanghellini, V, Ruggeri, E, del Vecchio, S, Salvi, A, Leonardi, R, Damiani, G, Capeci, W, Gabrielli, A, Mattioli, M, Martino, Gp, Biondi, L, Pettinari, P, Ghio, R, Dal Col, A, Minisola, S, Colangelo, L, Cilli, M, Labbadia, G, Afeltra, A, Marigliano, B, Pipita, Me, Castellino, P, Zanoli, L, Pignataro, S, Gennaro, A, Blanco, J, Saracco, V, Fogliati, M, Bussolino, C, Mete, F, Gino, M, Cittadini, A, Vigorito, C, Arcopinto, M, Salzano, A, Bobbio, E, Marra, Am, Sirico, D, Moreo, G, Gasparini, F, Prolo, S, Pina, G, Ballestrero, A, Ferrando, F, Berra, S, Dassi, S, Nava, Mc, Graziella, B, Baldassarre, S, Fragapani, S, Gruden, G, Galanti, G, Mascherini, G, Petri, C, Stefani, L, Girino, M, Piccinelli, V, Nasso, F, Gioffr?, V, Pasquale, M, Scattolin, G, Martinelli, S, Turrin, M, Sechi, L, Catena, C, Colussi, G, Passariello, N, Rinaldi, L, Berti, F, Famularo, G, Tarsitani, P, Castello, R, Pasino, M, Ceda, Gp, Maggio, Mg, Morganti, S, Artoni, A, Del Giacco, S, Firinu, D, Losa, F, Paoletti, G, Costanzo, G, Montalto, G, Licata, A, Malerba, V, Montalto, Fa, Lasco, A, Basile, G, Catalano, A, Malatino, L, Stancanelli, B, Terranova, V, Di Marca, S, Di Quattro, R, La Malfa, L, Caruso, R, Mecocci, P, Ruggiero, C, Boccardi, V, Meschi, T, Lauretani, F, Ticinesi, A, Nouvenne, A, Minuz, P, Fondrieschi, L, Pirisi, M, Fra, Gp, Sola, D, Porta, M, Riva, P, Quadri, R, Larovere, E, Novelli, M, Scanzi, G, Mengoli, C, Provini, S, Ricevuti, L, Simeone, E, Scurti, R, Tolloso, F, Tarquini, R, Valoriani, A, Dolenti, S, Vannini, G, Tedeschi, A, Trotta, L, Volpi, R, Bocchi, P, Vignali, A, Harari, S, Lonati, C, Cattaneo, M, Nieves, Rd, Alberto, Mm, Pedro, Ar, Vanessa, Lp, Lara, T, Xavier, Cv, Francesc, F, Jesus, Dm, Esperanza, Bt, Esther, Dcb, Maria, Sp, Romero, M, Blanca, Pl, Cristina, Lgc, Victoria, Vgm, Saez, L, Bosco, J, Susana, Sb, Marta, Ag, Concepcion, Gb, Antonio, Fm, Hernandez, Mg, Borrego, Mp, Raquel, Pc, Florencia, Pr, Beatriz, Go, Sara, Cg, Alfonso, Gcc, Marta, Pm, Alberto, Rc, Antonio, Aa, Montserrat, Gg, Angel, Brm, Manuel, Mj, Ignacio, Nv, Lucia, As, Alfonso, L, David, Rb, Iniguez, Vi, Monica, Rp, Ardoino I., Mannucci P.M., Nobili A., Franchi C., Tettamanti M., Pasina L., Corrao S., Marengoni A., Salerno F., Cesari M., Perticone F., Licata G., Violi F., Corazza G.R., Ardoino, I, Mannucci, P M, Nobili, A, Franchi, C, and Rinaldi, Luca
Subjects: Registrie, Male, 0301 basic medicine, Antibiotics, Logistic regression, 0302 clinical medicine, Drug Prescription, 80 and over, Prevalence, Immunology and Allergy, LS4_4, Hospital Mortality, Registries, 030212 general & internal medicine, Multivariate Analysi, Respiratory Tract Infections, Aged, 80 and over, Anti-Bacterial Agents, Hospitalization, Italy, Antibiotic use, Female, Human, Microbiology (medical), medicine.medical_specialty, Logistic Model, Internal medicine ward, medicine.drug_class, 030106 microbiology, Immunology, Socio-culturale, Drug Prescriptions, Microbiology, Odds, 03 medical and health sciences, Antibiotic resistance, Anti-Bacterial Agent, medicine, Older people, Aged, Geriatric Assessment, Humans, Logistic Models, Multivariate Analysis, Medical prescription, business.industry, Confidence interval, Antibiotic use, Internal medicine ward, Older people, Emergency medicine, business
Abstract: Objectives: The aims of this study were to assess (i) the prevalence of antibiotic use, (ii) factors associated with their use and (iii) the association with in-hospital mortality in a large sample of hospitalised older people in Italy.Methods: Data were obtained from the 2010-2017 REPOSI register held in more than 100 internal medicine and geriatric wards in Italy. Patients aged >= 65 years with at least one antibiotic prescription during their hospitalisation were selected. Multivariable logistic regression models were used to determine factors associated with antibiotic use.Results: A total of 5442 older patients were included in the analysis, of whom 2786 (51.2%) were prescribed antibiotics during their hospitalisation. The most frequently prescribed antibiotic class was beta-lactams, accounting for 50% of the total prescriptions. Poor physical independence, corticosteroid use and being hospitalised in Northern Italy were factors associated with a higher likelihood of being prescribed antibiotics. Antibiotic use was associated with an increased risk of in-hospital mortality (odds ratio = 2.52, 95% confidence interval 1.82-3.48) also when accounting for factors associated with their use.Conclusion: Hospitalised older people are often prescribed antibiotics. Factors related to poor physical independence and corticosteroid use are associated with increased antibiotic use. Being prescribed antibiotics is also associated with an increased risk of in-hospital death. These results demand the implementation of specific stewardship programmes to improve the correct use of antibiotics in hospital settings and to reduce the risk of antimicrobial resistance. (C) 2019 International Society for Antimicrobial Chemotherapy. Published by Elsevier Ltd. All rights reserved.
Published: 2019

50. The Large Hadron–Electron Collider at the HL-LHC

Author: Agostini, P., Aksakal, H., Apolinario, L., Goyal, A., Grames, J., Granados, E., Grassellino, A., Gunaydin, Y. O., Guo, Y. C., Guzey, V., Gwenlan, C., Hammad, A., Han, C. C., Apsimon, R., Harland-Lang, L., Haug, F., Hautmann, F., Hayden, D., Hessler, J., Helenius, I., Henry, J., Hernandez-Sanchez, J., Hesari, H., Hobbs, T. J., Apyan, A., Hod, N., Hoffstaetter, G. H., Holzer, B., Honorato, C. G., Hounsell, B., Hu, N., Hug, F., Huss, A., Hutton, A., Islam, R., Arduini, G., Iwamoto, S., Jana, S., Jansova, M., Jensen, E., Jones, T., Jowett, J. M., Kaabi, W., Kado, M., Kalinin, D. A., Karadeniz, H., Ari, V., Kawaguchi, S., Kaya, U., Khalek, R. A., Khanpour, H., Kilic, A., Klein, M., Klein, U., Kluth, S., Köksal, M., Kocak, F., Armbruster, A., Korostelev, M., Kostka, P., Krelina, M., Kretzschmar, J., Kuday, S., Kulipanov, G., Kumar, M., Kuze, M., Lappi, T., Larios, F., Armesto, N., Latina, A., Laycock, P., Lei, G., Levitchev, E., Levonian, Serguei V., Levy, A., Li, R., Li, X., Liang, H., Litvinenko, V., Auchmann, B., Liu, M., Liu, T., Liu, W., Liu, Y., Liuti, S., Lobodzinska, Ewelina, Longuevergne, D., Luo, X., Ma, W., Machado, M., Aulenbacher, K., Mandal, S., Mäntysaari, H., Marhauser, F., Marquet, C., Martens, A., Martin, R., Marzani, S., McFayden, J., Mcintosh, P., Mellado, B., Azuelos, G., Meot, F., Milanese, A., Milhano, J. G., Militsyn, B., Mitra, M., Moch, S., Mohammadi Najafabadi, M., Mondal, S., Moretti, S., Morgan, T., Alan, H., Backovic, S., Morreale, A., Nadolsky, P., Navarra, F., Nergiz, Z., Newman, P., Niehues, J., Nissen, E. A., Nowakowski, M., Okada, N., Olivier, G., Bailey, I., Olness, F., Olry, G., Osborne, J. A., Ozansoy, A., Pan, R., Parker, B., Patra, M., Paukkunen, H., Peinaud, Y., Pellegrini, D., Bailey, S., Perez-Segurana, G., Perini, D., Perrot, L., Pietralla, N., Pilicer, E., Pire, B., Pires, J., Placakyte, R., Poelker, M., Polifka, R., Balli, F., Polini, A., Poulose, P., Pownall, G., Pupkov, Y. A., Queiroz, F. S., Rabbertz, K., Radescu, V., Rahaman, R., Rai, S. K., Raicevic, N., Behera, S., Ratoff, P., Rashed, A., Raut, D., Raychaudhuri, S., Repond, J., Rezaeian, A. H., Rimmer, R., Rinolfi, L., Rojo, J., Rosado, A., Behnke, O., Ruan, X., Russenschuck, S., Sahin, M., Salgado, C. A., Sampayo, O. A., Satendra, K., Satyanarayan, N., Schenke, B., Schirm, K., Schopper, H., Ben-Zvi, I., Schott, M., Schulte, D., Schwanenberger, C., Sekine, T., Senol, A., Seryi, A., Setiniyaz, S., Shang, L., Shen, X., Shipman, N., Benedikt, M., Sinha, N., Slominski, W., Smith, S., Solans, C., Song, M., Spiesberger, H., Stanyard, J., Starostenko, A., Stasto, A., Stocchi, A., Bernauer, J., Strikman, M., Stuart, M. J., Sultansoy, S., Sun, H., Sutton, M., Szymanowski, L., Tapan, I., Tapia-Takaki, D., Tanaka, M., Tang, Y., Bertolucci, S., Tasci, A. T., Ten-Kate, A. T., Thonet, P., Tomas-Garcia, R., Tommasini, D., Trbojevic, D., Trott, M., Tsurin, I., Tudora, A., Turk Cakir, I., Alekhin, S., Biswal, S. S., Tywoniuk, K., Vallerand, C., Valloni, A., Verney, D., Vilella, E., Walker, D., Wallon, S., Wang, B., Wang, K., Blümlein, Johannes, Wang, X., Wang, Z. S., Wei, H., Welsch, C., Willering, G., Williams, P. H., Wollmann, D., Xiaohao, C., Xu, T., Yaguna, C. E., Bogacz, A., Yamaguchi, Y., Yamazaki, Y., Yang, H., Yilmaz, A., Yock, P., Yue, C. X., Zadeh, S. G., Zenaiev, O., Zhang, C., Zhang, J., Bonvini, M., Zhang, R., Zhang, Z., Zhu, G., Zhu, S., Zimmermann, F., Zomer, F., Zurita, J., Zurita, P., LHeC Collaboration, Group, FCC-he Study, Boonekamp, M., Bordry, F., Boroun, G. R., Bottura, L., Bousson, S., Bouzas, A. O., Allport, P. P., Bracco, C., Bracinik, J., Britzger, D., Brodsky, S. J., Bruni, C., Brüning, O., Burkhardt, H., Cakir, O., Calaga, R., Caldwell, A., Andari, N., Calıskan, A., Camarda, S., Catalan-Lasheras, N. C., Cassou, K., Cepila, J., Cetinkaya, V., Chetvertkova, V., Cole, B., Coleppa, B., Cooper-Sarkar, A., Andre, K. D. J., Cormier, E., Cornell, A. S., Corsini, R., Cruz-Alaniz, E., Currie, J., Curtin, D., D'Onofrio, M., Dainton, J., Daly, E., Das, A., Angal-Kalinin, D., Das, S. P., Dassa, L., de Blas, J., Delle Rose, L., Denizli, H., Deshpande, K. S., Douglas, D., Duarte, L., Dupraz, K., Dutta, S., Antusch, S., Efremov, A. V., Eichhorn, R., Eskola, K. J., Ferreiro, E. G., Fischer, O., Flores-Sánchez, O., Forte, S., Gaddi, A., Gao, J., Gehrmann, T., Aperio Bella, L., Gehrmann-De Ridder, A., Gerigk, F., Gilbert, A., Giuli, F., Glazov, Alexander, Glover, N., Godbole, R. M., Goddard, B., Gonçalves, V., Gonzalez-Sprinberg, G. A., Université Paris-Saclay, Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Centre d'Etudes Lasers Intenses et Applications (CELIA), Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11), Université de Strasbourg (UNISTRA), Centre de Physique Théorique [Palaiseau] (CPHT), École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), LHeC, FCC-he Study Group, Çetinkaya, Volkan, Çalışkan, Abdullatif, Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Bordeaux (UB), Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X), Agostini P, Aksakal H, Duarte Lucía, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Física., Helsinki Institute of Physics, Particle Physics and Astrophysics, and Calıskan, Abdullatif
Subjects: energy recovery, lepton nucleus: scattering, parton: distribution function, hiukkasfysiikka, 7. Clean energy, 01 natural sciences, accelerator physics, High Energy Physics - Phenomenology (hep-ph), HEAVY FLAVOR CONTRIBUTIONS, energy-recovery- linac, Nuclear Experiment, colliding beams [electron p], deep-inelastic scattering, top and electroweak physics, new physics, Physics, STRUCTURE-FUNCTION RATIOS, Monte Carlo [numerical calculations], buildings, primary [vertex], High Energy Physics - Phenomenology, electron p: colliding beams, kinematics, Nuclear Physics - Theory, final state: hadronic, p: distribution function, beyond Standard Model, vertex: primary, numerical calculations: Monte Carlo, distribution function [parton], High-lumiLHC, STRUCTURE-FUNCTION F-2(X, [PHYS.NUCL]Physics [physics]/Nuclear Theory [nucl-th], ion: beam, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], 114 Physical sciences, Nuclear Theory (nucl-th), deep inelastic scattering, quantum chromodynamics, ddc:530, 010306 general physics, high-lumi LHC, QCD, Higgs, nuclear physics, beyond standard Model, 010308 nuclear & particles physics, resolution, scattering [electron p], structure function [nucleus], sensitivity, beam [electron], energy-recovery-linac, acceptance, Nuclear Theory, HIGH-ENERGY FACTORIZATION, distribution function [p], density [parton], High-lumi LHC, High Energy Physics - Experiment, design [detector], High Energy Physics - Experiment (hep-ex), electron: linear accelerator, electron hadron: scattering, CERN LHC Coll: upgrade, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], scattering [electron hadron], FCC, electron: beam, Nuclear Experiment (nucl-ex), linear accelerator [electron], lattice, superconductivity, Energy-recoverylinac, Beyond Standard Mode, Nuclear physics, electron nucleus: colliding beams, parton: density, colliding beams [electron nucleus], Particle Physics - Experiment, NUCLEON STRUCTURE FUNCTIONS, Nuclear and High Energy Physics, scattering [lepton nucleus], beam [ion], FOS: Physical sciences, nucleus: structure function, hadronic [final state], electron p: scattering, TRANSVERSE-MOMENTUM DEPENDENCE, 0103 physical sciences, Nuclear Physics - Experiment, structure, upgrade [CERN LHC Coll], detector: design, Particle Physics - Phenomenology, DEEP-INELASTIC-SCATTERING, electroweak interaction, 3-LOOP SPLITTING FUNCTIONS, CLASSICAL RADIATION ZEROS, calibration, Accelerators and Storage Rings, magnet, high [current], 13. Climate action, [PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph], LHeC, Physics::Accelerator Physics, JET CROSS-SECTIONS, High Energy Physics::Experiment, current: high
Abstract: The Large Hadron-Electron Collider (LHeC) is designed to move the field of deep inelastic scattering (DIS) to the energy and intensity frontier of particle physics. Exploiting energy-recovery technology, it collides a novel, intense electron beam with a proton or ion beam from the High-Luminosity Large Hadron Collider (HL-LHC). The accelerator and interaction region are designed for concurrent electron-proton and proton-proton operations. This report represents an update to the LHeC's conceptual design report (CDR), published in 2012. It comprises new results on the parton structure of the proton and heavier nuclei, QCD dynamics, and electroweak and top-quark physics. It is shown how the LHeC will open a new chapter of nuclear particle physics by extending the accessible kinematic range of lepton-nucleus scattering by several orders of magnitude. Due to its enhanced luminosity and large energy and the cleanliness of the final hadronic states, the LHeC has a strong Higgs physics programme and its own discovery potential for new physics. Building on the 2012 CDR, this report contains a detailed updated design for the energy-recovery electron linac (ERL), including a new lattice, magnet and superconducting radio-frequency technology, and further components. Challenges of energy recovery are described, and the lower-energy, high-current, three-turn ERL facility, PERLE at Orsay, is presented, which uses the LHeC characteristics serving as a development facility for the design and operation of the LHeC. An updated detector design is presented corresponding to the acceptance, resolution, and calibration goals that arise from the Higgs and parton-density-function physics programmes. This paper also presents novel results for the Future Circular Collider in electron-hadron (FCC-eh) mode, which utilises the same ERL technology to further extend the reach of DIS to even higher centre-of-mass energies., Journal of Physics G: Nuclear and Particle Physics, 48 (11), ISSN:0305-4616, ISSN:0954-3899, ISSN:1361-6471, ISSN:0954-3889
Published: 2021

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