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3 results on '"Braakhuis, Linde L F"'

1. Systematic review of published literature on oxaliplatin and mitomycin C as chemotherapeutic agents for hyperthermic intraperitoneal chemotherapy in patients with peritoneal metastases from colorectal cancer

Author

Wisselink, Daan D, Braakhuis, Linde L F, Gallo, Gaetano, van Grevenstein, Wilhelmina M U, van Dieren, Susan, Kok, Niels F M, de Reuver, Philip R, Tanis, Pieter J, de Hingh, Ignace H J T, Wisselink, Daan D, Braakhuis, Linde L F, Gallo, Gaetano, van Grevenstein, Wilhelmina M U, van Dieren, Susan, Kok, Niels F M, de Reuver, Philip R, Tanis, Pieter J, and de Hingh, Ignace H J T

Published
2019

2. Systematic review of published literature on oxaliplatin and mitomycin C as chemotherapeutic agents for hyperthermic intraperitoneal chemotherapy in patients with peritoneal metastases from colorectal cancer

Author

MS CGO, Cancer, Wisselink, Daan D, Braakhuis, Linde L F, Gallo, Gaetano, van Grevenstein, Wilhelmina M U, van Dieren, Susan, Kok, Niels F M, de Reuver, Philip R, Tanis, Pieter J, de Hingh, Ignace H J T, MS CGO, Cancer, Wisselink, Daan D, Braakhuis, Linde L F, Gallo, Gaetano, van Grevenstein, Wilhelmina M U, van Dieren, Susan, Kok, Niels F M, de Reuver, Philip R, Tanis, Pieter J, and de Hingh, Ignace H J T

Published
2019

3. Systematic review of published literature on oxaliplatin and mitomycin C as chemotherapeutic agents for hyperthermic intraperitoneal chemotherapy in patients with peritoneal metastases from colorectal cancer.

Author

Wisselink DD, Braakhuis LLF, Gallo G, van Grevenstein WMU, van Dieren S, Kok NFM, de Reuver PR, Tanis PJ, and de Hingh IHJT

Subjects
Antineoplastic Agents therapeutic use, Colorectal Neoplasms drug therapy, Colorectal Neoplasms pathology, Colorectal Neoplasms surgery, Combined Modality Therapy, Cytoreduction Surgical Procedures, Humans, Peritoneal Neoplasms drug therapy, Peritoneal Neoplasms secondary, Peritoneal Neoplasms surgery, Colorectal Neoplasms therapy, Hyperthermia, Induced, Mitomycin therapeutic use, Oxaliplatin therapeutic use, Peritoneal Neoplasms therapy
Abstract

Background: The role of hyperthermic intraperitoneal chemotherapy (HIPEC) with oxaliplatin in addition to cytoreductive surgery (CRS) has recently been questioned in peritoneal metastases of colorectal cancer. Whether this applies to all published CRS/HIPEC regimens is unclear., Methods: A systematic literature search identified 46 studies on CRS/HIPEC using either oxaliplatin of mitomycin C with at least one oncological outcome parameter RESULTS: Oxaliplatin and mitomycin C studies were comparable regarding extent of disease, but differed substantially regarding synchronous versus metachronous presentation, application of neo-adjuvant systemic chemotherapy, duration of HIPEC, and completeness of cytoreduction for at least one of the oncological endpoints. Severe postoperative complication rate seemed significantly higher after oxaliplatin-based CRS/HIPEC., Conclusion: Published cohorts on oxaliplatin-based CRS/HIPEC differed essentially from MMC-based procedures, especially considering the application of oxaliplatin-containing neo-adjuvant systemic therapy and shorter exposure time to intraperitoneal chemotherapy in oxaliplatin studies. No meaningful comparison could be made regarding DFS and OS., (Copyright © 2019 Elsevier B.V. All rights reserved.)

Published
2019
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