352 results on '"Brüggemann, Roger J. M."'
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2. How to Dose Vancomycin in Overweight and Obese Patients with Varying Renal (Dys)function in the Novel Era of AUC 400–600 mg·h/L-Targeted Dosing
3. High Variability in Isavuconazole Unbound Fraction in Clinical Practice: A Call to Reconsider Pharmacokinetic/Pharmacodynamic Targets and Breakpoints
4. Population Pharmacokinetics of Total and Unbound Isavuconazole in Critically Ill Patients: Implications for Adaptive Dosing Strategies
5. Correction to: An Integral Pharmacokinetic Analysis of Piperacillin and Tazobactam in Plasma and Urine in Critically Ill Patients
6. Ciprofloxacin Pharmacokinetics After Oral and Intravenous Administration in (Morbidly) Obese and Non-obese Individuals: A Prospective Clinical Study
7. An Integral Pharmacokinetic Analysis of Piperacillin and Tazobactam in Plasma and Urine in Critically Ill Patients
8. Pooled Population Pharmacokinetic Analysis for Exploring Ciprofloxacin Pharmacokinetic Variability in Intensive Care Patients
9. Isavuconazole as prophylaxis and therapy for invasive fungal diseases: a real-life observational study.
10. Evaluation of the drug–drug interaction between triazole antifungals and cystic fibrosis transmembrane conductance regulator modulators in a real-life cohort
11. Development and validation of an UPLC–MS/MS assay for the simultaneous quantification of seven commonly used antibiotics in human plasma and its application in therapeutic drug monitoring
12. Taskforce report on the diagnosis and clinical management of COVID-19 associated pulmonary aspergillosis
13. COVID-19-associated Aspergillus tracheobronchitis: the interplay between viral tropism, host defence, and fungal invasion
14. Oral Antibiotics in Patients with Short Bowel Syndrome: Do or Don’t?
15. How to Dose Vancomycin in Overweight and Obese Patients with Varying Renal (Dys)function in the Novel Era of AUC 400–600 mg·h/L-Targeted Dosing
16. Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition: an expert opinion
17. Pharmacokinetics and Pharmacodynamics of Posaconazole
18. A Population Pharmacokinetic Model Does Not Predict the Optimal Starting Dose of Tacrolimus in Pediatric Renal Transplant Recipients in a Prospective Study: Lessons Learned and Model Improvement
19. A Prospective Clinical Study Characterizing the Influence of Morbid Obesity on the Pharmacokinetics of Gentamicin: Towards Individualized Dosing in Obese Patients
20. Antifungal PK/PD in the Critically Ill
21. Dosing Recommendations for Vancomycin in Children and Adolescents with Varying Levels of Obesity and Renal Dysfunction: a Population Pharmacokinetic Study in 1892 Children Aged 1–18 Years
22. The potential impact of hematocrit correction on evaluation of tacrolimus target exposure in pediatric kidney transplant patients
23. Correction to: Tobramycin Clearance Is Best Described by Renal Function Estimates in Obese and Nonobese Individuals: Results of a Prospective Rich Sampling Pharmacokinetic Study
24. Pharmacokinetic investigations of isavuconazole in paediatric cancer patients show reduced exposure of isavuconazole after opening capsules for administration via a nasogastric tube.
25. A Population Pharmacokinetic Model to Predict the Individual Starting Dose of Tacrolimus Following Pediatric Renal Transplantation
26. Repurposing antifungals: population pharmacokinetics of itraconazole and hydroxy-itraconazole following administration of a nanocrystal formulation
27. Tobramycin Clearance Is Best Described by Renal Function Estimates in Obese and Non-obese Individuals: Results of a Prospective Rich Sampling Pharmacokinetic Study
28. Oral antimicrobial agents in patients with short bowel syndrome: worth a try!
29. Effect of Haloperidol on Survival Among Critically Ill Adults With a High Risk of Delirium: The REDUCE Randomized Clinical Trial
30. Antifungal PK/PD in the Critically Ill
31. Dose Reduction of Caspofungin in Intensive Care Unit Patients with Child Pugh B Will Result in Suboptimal Exposure
32. Fundament and Prerequisites for the Application of an Antifungal TDM Service
33. Clinical Relevance of the Pharmacokinetic Interactions of Azole Antifungal Drugs with Other Coadministered Agents
34. Single-Dose Fluconazole versus Standard 2-Week Therapy for Oropharyngeal Candidiasis in HIV-Infected Patients: A Randomized, Double-Blind, Double-Dummy Trial
35. Aspergillus Test Profiles and Mortality in Critically Ill COVID-19 Patients
36. Molecular Mechanisms of 5-Fluorocytosine Resistance in Yeasts and Filamentous Fungi
37. Pharmacokinetic drug interactions of azoles
38. Dysregulated Innate and Adaptive Immune Responses Discriminate Disease Severity in COVID-19
39. Moderate correlation between systemic IL‐6 responses and CRP with trough concentrations of voriconazole
40. A Multidisciplinary Approach to Fungal Infections: One-Year Experiences of a Center of Expertise in Mycology
41. Efficacy and pharmacodynamics of voriconazole combined with anidulafungin in azole-resistant invasive aspergillosis
42. Effect of azole antifungal therapy on vincristine toxicity in childhood acute lymphoblastic leukaemia
43. Outcomes Associated With Use of a Kinin B2 Receptor Antagonist Among Patients With COVID-19
44. Dose recommendations for gentamicin in the real-world obese population with varying body weight and renal (dys)function
45. Diagnosing COVID-19-associated pulmonary aspergillosis
46. Optimization of flucloxacillin dosing regimens in critically ill patients using population pharmacokinetic modelling of total and unbound concentrations
47. Efficacy and safety of selective decontamination of the digestive tract (SDD) to prevent recurrent hepatic cyst infections in polycystic liver disease: a retrospective case series
48. Higher Dosage of Ciprofloxacin Necessary in Critically Ill Patients: A New Dosing Algorithm Based on Renal Function and Pathogen Susceptibility
49. Prophylaxis Against Invasive Fungal Disease for Neutropenic Children and Young Adults
50. Implications for IV posaconazole dosing in the era of obesity
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