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50 results on '"Bozza, Giovanni"'

4. Docetaxel and prednisone with or without enzalutamide as first-line treatment in patients with metastatic castration-resistant prostate cancer: CHEIRON, a randomised phase II trial

Author

Caffo, Orazio, primary, Ortega, Cinzia, additional, Nolè, Franco, additional, Gasparro, Donatello, additional, Mucciarini, Claudia, additional, Aieta, Michele, additional, Zagonel, Vittorina, additional, Iacovelli, Roberto, additional, De Giorgi, Ugo, additional, Facchini, Gaetano, additional, Veccia, Antonello, additional, Palesandro, Erica, additional, Verri, Elena, additional, Buti, Sebastiano, additional, Razzini, Giorgia, additional, Bozza, Giovanni, additional, Maruzzo, Marco, additional, Ciccarese, Chiara, additional, Schepisi, Giuseppe, additional, Rossetti, Sabrina, additional, Maines, Francesca, additional, Kinspergher, Stefania, additional, Fratino, Lucia, additional, Ermacora, Paola, additional, Nicodemo, Maurizio, additional, Giordano, Monica, additional, Sartori, Donata, additional, Scapoli, Daniela, additional, Sabbatini, Roberto, additional, Lo Re, Giovanni, additional, Morelli, Franco, additional, D’Angelo, Alessandro, additional, Vittimberga, Isabella, additional, Lippe, Paolo, additional, Carrozza, Francesco, additional, Messina, Caterina, additional, Galli, Luca, additional, Valcamonico, Francesca, additional, Porta, Camillo, additional, Pappagallo, Giovanni, additional, and Aglietta, Massimo, additional

Published
2021
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5. An inexact Newton-based approach to microwave imaging within the contrast source formulation

Author

Bozza, Giovanni and Pastorino, Matteo

Subjects
Algorithms -- Usage, Imaging systems -- Methods, Electromagnetic waves -- Scattering, Electromagnetic waves -- Observations, Microwave communications -- Equipment and supplies, Microwave communications -- Design and construction, Microwave communications -- Usage, Algorithm, Microwave transmission equipment, Business, Computers, Electronics, Electronics and electrical industries
Abstract

In this paper an approach to microwave imaging based on an Inexact-Newton method within the contrast source formulation of the inverse scattering problem is considered. In this framework, the iteratively linearized equations of the inverse problem are solved by means of the regularizing truncated Landweber algorithm. This approach allows an effective and robust tool to inspect dielectric objects, as it is shown by the reported numerical results. Moreover, thanks to the structure of the involved integral equations within the contrast source formulation, computer memory saving can be obtained with respect to the electric field integral equation framework. Finally, the proposed method is validated against experimental data, kindly provided by the Institute Fresnel, Marseille, France. Index Terms--Electromagnetic inverse scattering, Newton methods, contrast source formulation.

Published
2009

6. A hybrid approach to 3D microwave imaging by using linear sampling and ACO

Author

Brignone, Massimo, Bozza, Giovanni, Randazzo, Andrea, Piana, Michele, and Pastorino, Matteo

Subjects
Algorithms -- Usage, Mathematical optimization -- Research, Stochastic analysis -- Methods, Statistical sampling -- Methods, Microwave communications -- Research, Imaging systems -- Design and construction, Imaging systems -- Technology application, Electromagnetic waves -- Scattering, Electromagnetic waves -- Evaluation, Algorithm, Imaging technology, Technology application, Business, Computers, Electronics, Electronics and electrical industries
Abstract

A hybrid approach is proposed to inspect three-dimensional homogeneous dielectric scatterers by using microwaves. Namely, the considered method consists in two steps: first, the supports of the scatterers are retrieved by the linear sampling method; then the permittivities of the targets are estimated by an ant colony optimization algorithm. The described strategy combines the efficiency of the linear sampling method with the global optimization capabilities of the stochastic procedure. Numerical results assess the capabilities of the approach also in the presence of noise. Index Terms--Ant colony optimization (ACO), inverse scattering, linear sampling method (LSM), stochastic methods.

Published
2008

10. Pain predicts overall survival in men with metastatic castration-resistant prostate cancer treated with radium-223

Author

Roviello,Giandomenico, Gallicchio,Rosj, Bozza,Giovanni, Rodriquenz,Maria Grazia, Aieta,Michele, Storto,Giovanni, Roviello,Giandomenico, Gallicchio,Rosj, Bozza,Giovanni, Rodriquenz,Maria Grazia, Aieta,Michele, and Storto,Giovanni

Abstract

Giandomenico Roviello,1 Rosj Gallicchio,2 Giovanni Bozza,1 Maria Grazia Rodriquenz,1 Michele Aieta,1 Giovanni Storto2 1Division of Medical Oncology, Department of Onco-Hematology, IRCCS CROB, Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, PZ, Italy; 2Nuclear Medicine Department, IRCCS CROB, Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, PZ, Italy Background: Radium-223 dichloride is an alpha emitter approved for metastatic castration-resistant prostate cancer (mCRPC). Unfortunately, little data are available on the prognostic factors during radium-223-based therapy.Patients and methods: Patients with histologically confirmed progressive CRPC with two or more bone metastases and symptomatic disease were eligible. Previous therapy with a novel hormonal therapy was allowed. The patients received six intravenous injections of radium-223 every 4 weeks. A visual analog scale (VAS) was adopted to evaluate patients’ basal pain.Results: A total of 25 patients were evaluated. Of these, 6 (24%) reported VAS <4. After a median follow-up of 8 months, all patients died with a median overall survival of 8.3 months (95% CI: 5.2–11.8 months), 12.6 months in the patients with VAS <4 vs 6.6 months in the patients with VAS ≥4 (P=0.03).Conclusion: The present study suggests that VAS could be prognostic of the survival of mCRPC treated with radium-223 irrespective of the limitations of a small number of patients and the retrospective nature of the data. Keywords: radium-223, pain, prostate cancer, radioactive therapy

Published
2018

11. Lenvatinib for the treatment of renal cell carcinoma

Author

Roviello, Giandomenico, primary, Corona, Silvia Paola, additional, Bozza, Giovanni, additional, Aieta, Michele, additional, Generali, Daniele, additional, Rodriquenz, Maria Grazia, additional, Mileo, Anna Maria, additional, Imperatori, Marco, additional, Ianza, Anna, additional, Conca, Raffaele, additional, and Sobhani, Navid, additional

Published
2018
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13. Pain predicts overall survival in men with metastatic castration-resistant prostate cancer treated with radium-223.

Author

Roviello, Giandomenico, Gallicchio, Rosj, Bozza, Giovanni, Rodriquenz, Maria Grazia, Aieta, Michele, and Storto, Giovanni

Subjects
CASTRATION-resistant prostate cancer, VISUAL analog scale, INTRAVENOUS injections, BONE metastasis
Abstract

Background: Radium-223 dichloride is an alpha emitter approved for metastatic castration-resistant prostate cancer (mCRPC). Unfortunately, little data are available on the prognostic factors during radium-223-based therapy. Patients and methods: Patients with histologically confirmed progressive CRPC with two or more bone metastases and symptomatic disease were eligible. Previous therapy with a novel hormonal therapy was allowed. The patients received six intravenous injections of radium-223 every 4 weeks. A visual analog scale (VAS) was adopted to evaluate patients' basal pain. Results: A total of 25 patients were evaluated. Of these, 6 (24%) reported VAS <4. After a median follow-up of 8 months, all patients died with a median overall survival of 8.3 months (95% CI: 5.2–11.8 months), 12.6 months in the patients with VAS <4 vs 6.6 months in the patients with VAS ≥4 (P=0.03). Conclusion: The present study suggests that VAS could be prognostic of the survival of mCRPC treated with radium-223 irrespective of the limitations of a small number of patients and the retrospective nature of the data. [ABSTRACT FROM AUTHOR]

Published
2019
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14. A multicenter phase II trial of nab‐paclitaxel and capecitabine in HER‐2 negative and triple‐ negative advanced breast cancer: Could be an old regimen a valid approach to a changing disease?

Author

Ciccarese, Mariangela, Orlando, Laura, Fedele, Palma, Schiavone, Paola, Maiello, Evaristo, Cilenti, Giuseppina, Aieta, Michele, Bozza, Giovanni, Forcignanò, Rosachiara, Febbraro, Antonio, Bordonaro, Roberto, Romito, Sante, Rinaldi, Antonio, Borsellino, Nicolo', Riccardi, Ferdinando, Pisconti, Salvatore, Lorusso, Vito, Colucci, Giuseppe, Surico, Giammarco, and Saracino, Valeria

Subjects
ANTINEOPLASTIC agents, THERAPEUTIC use of antimetabolites, ANTIMETABOLITES, BREAST tumors, CANCER chemotherapy, CANCER patients, LONGITUDINAL method, MEDICAL cooperation, METASTASIS, PACLITAXEL, RESEARCH
Abstract

The article discusses an endocrine sensitive disease, the treatment of choice has hormonal therapy plus CDK4/6 inhibitors that proposed sequentially endocrine resistance occurs. Topics include the use of chemotherapy regimen has suggested in case of progressive disease became refractory to hormonal treatment; and presence of an endocrine sensitive disease, the treatment of choice has hormonal therapy plus CDK4/6 inhibitors has proposed endocrine resistance.

Published
2020
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24. A Two-Step Iterative Inexact-Newton Method for Electromagnetic Imaging of Dielectric Structures from Real Data

Author

Estatico, Claudio, Bozza, Giovanni, Massa, Andrea, Pastorino, Matteo, and Randazzo, Andrea

Subjects
TK7885 Computer Engineering, TK5105.5 Computer Networks, QC661 Electromagnetic Theory, QC760 Electromagnetism
Abstract

A new inverse scattering method is assessed against some of the real input data measured by the Institut Fresnel, Marseille, France. The method is based on the application of an Inexact-Newton method to the Lippmann-Schwinger integral equation of the inverse scattering problem within the second-order Born approximation. The regularization properties of the approach are evaluated by considering the reconstruction of multiple dielectric cylinders.

Published
2005

41. The epidermal growth factor receptors as biological targets in penile cancer

Author

Di Lorenzo, Giuseppe, Buonerba, Carlo, Ferro, Matteo, Calderoni, Giuseppe, Bozza, Giovanni, Federico, Piera, Tedesco, Beatrice, Ruggieri, Vitalba, and Aieta, Michele

Abstract

Penile cancer is a rare disease, with an incidence that is higher in less developed countries and is in the range of 1 – 10 per 100000 men worldwide. Early diagnosis is essential for cure, as 5 year cancer-specific survival is 90 – 100 % in patients with intraepithelial neoplasms and in those with low-grade superficial tumors without lymphovascular invasion, but it drops to 30% in men with multiple mobile or bilateral inguinal lymph nodes. The EGFR family plays a major role in penile cancer biology, with distinct receptors being involved in HPV-positive and -negative tumors. A number of anti-EGFR agents were used in penile cancer patients outside the context of a clinical trial, mainly as a salvage treatment after failure of first-line chemotherapy. A total of 28 patients received anti-EGFR monoclonal antibodies, with 50% of them showing a response to treatment, and a median PFS of ∼ 3 months. The rarity of the disease poses great challenge in terms of education and awareness of the general population, planning of preventive measures on a large scale, as well as conduction of prospective trials and approval of high-cost biological therapy.

Published
2015
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42. A New Microwave Axial Tomograph for the Inspection of Dielectric Materials.

Author

Salvadè, Andrea, Pastorino, Matteo, Monleone, Ricardo, Bozza, Giovanni, and Randazzo, Andrea

Subjects
TOMOGRAPH, IMAGING systems, DIELECTRICS, COMPUTER software, COMPUTER input-output equipment, NEWTON-Raphson method, ITERATIVE methods (Mathematics), RADAR
Abstract

In this paper, the development of a microwave axial tomograph for the inspection of dielectric materials is discussed. In particular, hardware and software solutions are pointed out. An experimental bistatic imaging setup is described. Moreover, the results of several forward-scattering simulations, which are aimed at defining suitable working conditions, are reported. Finally, to invert the collected field-scattered data, a deterministic inexact Newton method is applied. The approach is evaluated by using synthetic data, and the results of a preliminary experimental reconstruction are reported. [ABSTRACT FROM AUTHOR]

Published
2009
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44. A Two-Step Iterative Inexact-Newton Method for Electromagnetic Imaging of Dielectric Structures from Real Data

Author

Estatico, Claudio, Bozza, Giovanni, Massa, Andrea, Pastorino, Matteo, Randazzo, Andrea, Estatico, Claudio, Bozza, Giovanni, Massa, Andrea, Pastorino, Matteo, and Randazzo, Andrea

Abstract

A new inverse scattering method is assessed against some of the real input data measured by the Institut Fresnel, Marseille, France. The method is based on the application of an Inexact-Newton method to the Lippmann-Schwinger integral equation of the inverse scattering problem within the second-order Born approximation. The regularization properties of the approach are evaluated by considering the reconstruction of multiple dielectric cylinders.

45. A Two-Step Iterative Inexact-Newton Method for Electromagnetic Imaging of Dielectric Structures from Real Data

Author

Estatico, Claudio, Bozza, Giovanni, Massa, Andrea, Pastorino, Matteo, Randazzo, Andrea, Estatico, Claudio, Bozza, Giovanni, Massa, Andrea, Pastorino, Matteo, and Randazzo, Andrea

Abstract

A new inverse scattering method is assessed against some of the real input data measured by the Institut Fresnel, Marseille, France. The method is based on the application of an Inexact-Newton method to the Lippmann-Schwinger integral equation of the inverse scattering problem within the second-order Born approximation. The regularization properties of the approach are evaluated by considering the reconstruction of multiple dielectric cylinders.

46. A Two-Step Iterative Inexact-Newton Method for Electromagnetic Imaging of Dielectric Structures from Real Data

Author

Estatico, Claudio, Bozza, Giovanni, Massa, Andrea, Pastorino, Matteo, Randazzo, Andrea, Estatico, Claudio, Bozza, Giovanni, Massa, Andrea, Pastorino, Matteo, and Randazzo, Andrea

Abstract

A new inverse scattering method is assessed against some of the real input data measured by the Institut Fresnel, Marseille, France. The method is based on the application of an Inexact-Newton method to the Lippmann-Schwinger integral equation of the inverse scattering problem within the second-order Born approximation. The regularization properties of the approach are evaluated by considering the reconstruction of multiple dielectric cylinders.

47. A Two-Step Iterative Inexact-Newton Method for Electromagnetic Imaging of Dielectric Structures from Real Data

Author

Estatico, Claudio, Bozza, Giovanni, Massa, Andrea, Pastorino, Matteo, Randazzo, Andrea, Estatico, Claudio, Bozza, Giovanni, Massa, Andrea, Pastorino, Matteo, and Randazzo, Andrea

Abstract

A new inverse scattering method is assessed against some of the real input data measured by the Institut Fresnel, Marseille, France. The method is based on the application of an Inexact-Newton method to the Lippmann-Schwinger integral equation of the inverse scattering problem within the second-order Born approximation. The regularization properties of the approach are evaluated by considering the reconstruction of multiple dielectric cylinders.

48. A Two-Step Iterative Inexact-Newton Method for Electromagnetic Imaging of Dielectric Structures from Real Data

Author

Estatico, Claudio, Bozza, Giovanni, Massa, Andrea, Pastorino, Matteo, Randazzo, Andrea, Estatico, Claudio, Bozza, Giovanni, Massa, Andrea, Pastorino, Matteo, and Randazzo, Andrea

Abstract

A new inverse scattering method is assessed against some of the real input data measured by the Institut Fresnel, Marseille, France. The method is based on the application of an Inexact-Newton method to the Lippmann-Schwinger integral equation of the inverse scattering problem within the second-order Born approximation. The regularization properties of the approach are evaluated by considering the reconstruction of multiple dielectric cylinders.

49. A Two-Step Iterative Inexact-Newton Method for Electromagnetic Imaging of Dielectric Structures from Real Data

Author

Estatico, Claudio, Bozza, Giovanni, Massa, Andrea, Pastorino, Matteo, Randazzo, Andrea, Estatico, Claudio, Bozza, Giovanni, Massa, Andrea, Pastorino, Matteo, and Randazzo, Andrea

Abstract

A new inverse scattering method is assessed against some of the real input data measured by the Institut Fresnel, Marseille, France. The method is based on the application of an Inexact-Newton method to the Lippmann-Schwinger integral equation of the inverse scattering problem within the second-order Born approximation. The regularization properties of the approach are evaluated by considering the reconstruction of multiple dielectric cylinders.

50. A Two-Step Iterative Inexact-Newton Method for Electromagnetic Imaging of Dielectric Structures from Real Data

Author

Estatico, Claudio, Bozza, Giovanni, Massa, Andrea, Pastorino, Matteo, Randazzo, Andrea, Estatico, Claudio, Bozza, Giovanni, Massa, Andrea, Pastorino, Matteo, and Randazzo, Andrea

Abstract

A new inverse scattering method is assessed against some of the real input data measured by the Institut Fresnel, Marseille, France. The method is based on the application of an Inexact-Newton method to the Lippmann-Schwinger integral equation of the inverse scattering problem within the second-order Born approximation. The regularization properties of the approach are evaluated by considering the reconstruction of multiple dielectric cylinders.

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