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Objectives: Various risk assessment tools have been developed to evaluate the risk of hereditary breast/ovarian cancer. This study aims to estimate the risk of breast/ovarian cancer in a sample of the general population in Iran using the IBIS software. Methods: A total of 2020 women aged 18-79 years were consecutively selected from the gynecology clinic of Imam Hossein Medical Center between April 2019 and 2021. The Tyrer-Cusick (IBIS) questionnaire was used to collect data on variables such as age, BMI, age at menarche, age at first pregnancy, menopausal status, history of hormone replacement therapy (HRT), and family history of breast/ovarian cancer. The risks of developing breast/ovarian cancer were calculated, with patients having a calculated risk of more than 20% considered high-risk and those below 20% considered low-risk. Results: Out of the 2020 cases studied, 69 (3.4%) were classified as high-risk for developing breast/ovarian cancer. The moderate risk of breast/ovarian cancer in patients with a positive family history was 18.47%, compared to 10.15% in those without a family history. All high-risk individuals had a positive family history, while only 9.4% of the low-risk population had a family history; this difference was statistically significant (p<0.001). Conclusion: Routine assessment of family history of cancer in all patients is recommended, with positive cases being further evaluated using a cancer risk assessment tool and referred for genetic counseling as appropriate. [ABSTRACT FROM AUTHOR]

Objectives: The accurate, rapid diagnosis of stress urinary incontinence (SUI) in women can profoundly improve their sexual and psychosocial life. In this study, the diagnostic power of SUI was assessed by transperineal ultrasound. Methods: In this hospital‐based case‐control study, married women who were referred to the gynecologic and ultrasound wards with negative urinalysis and culture results were enrolled by random sampling. Patients with positive cough signs based on the urodynamic testing data were considered cases, whereas control women showed no cough symptoms and were recruited from the same ward. Results: There was a significant difference (P <.001) in bladder neck descent (mean ± SD, 10.89 ± 5.51 versus 7.08 ± 2.60 mm, respectively; P =.0001) and the retrovesical (β) angle with the Valsalva maneuver (144.22° ± 19.63° versus 111.81° ± 24.47°; P <.001) between the case and control groups. Also, the β angle without the Valsalva maneuver was higher in the case group (112.35° ± 23.10°) than the control group (120.17° ± 25.16°; P =.001). There was no case of a urinary leak, urethral diverticulitis, a bladder stone or mass, and cystourethrocele in the patients of each group. The results of multivariate logistic regression with a backward method showed that bladder neck descent (odds ratio [OR], 1.24; 95% confidence interval [CI], 1.09–1.40), the β angles with and without the Valsalva maneuver (OR, 1.1; 95% CI, 1.06–1.13; and OR, 1.04; 95% CI, 1.01–1.06) were the predictors of SUI. A β angle higher than 127° with the Valsalva maneuver, with an area under the curve of 0.89 (95% CI, 0.75–0.96), could very well predict the SUI response. This finding shows that it can be very well used to distinguish between normal and non‐normal responses, with 89% sensitivity and 79% specificity. Conclusions: The β angle with the Valsalva maneuver could very well predict the SUI response. [ABSTRACT FROM AUTHOR]