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Mindfulness witnessed a substantial popularity surge in the past decade, especially as digitally self-administered interventions became available at relatively low costs. Yet, it is uncertain whether they effectively help reduce stress. In a preregistered (OSF https://doi.org/10.17605/OSF.IO/UF4JZ ; retrospective registration at ClinicalTrials.gov NCT06308744 ) multi-site study (nsites = 37, nparticipants = 2,239, 70.4% women, Mage = 22.4, s.d.age = 10.1, all fluent English speakers), we experimentally tested whether four single, standalone mindfulness exercises effectively reduced stress, using Bayesian mixed-effects models. All exercises proved to be more efficacious than the active control. We observed a mean difference of 0.27 (d = -0.56; 95% confidence interval, -0.43 to -0.69) between the control condition (M = 1.95, s.d. = 0.50) and the condition with the largest stress reduction (body scan: M = 1.68, s.d. = 0.46). Our findings suggest that mindfulness may be beneficial for reducing self-reported short-term stress for English speakers from higher-income countries.

Through diverse roles, zinc determines a greater number of critical life functions than any other single micronutrient. Beyond the well-recognized importance of zinc for child growth and resistance to infections, zinc has numerous specific roles covering the regulation of glucose metabolism, and growing evidence links zinc deficiency with increased risk of diabetes and cardiometabolic disorders. Zinc nutriture is, thus, vitally important to health across the life course. Zinc deficiency is also one of the most common forms of micronutrient malnutrition globally. A clearer estimate of the burden of health disparity attributable to zinc deficiency in adulthood and later life emerges when accounting for its contribution to global elevated fasting blood glucose and related noncommunicable diseases (NCDs). Yet progress attenuating its prevalence has been limited due, in part, to the lack of sensitive and specific methods to assess human zinc status. This narrative review covers recent developments in our understanding of zincs role in health, the impact of the changing climate and global context on zinc intake, novel functional biomarkers showing promise for monitoring population-level interventions, and solutions for improving population zinc intake. It aims to spur on implementation of evidence-based interventions for preventing and controlling zinc deficiency across the life course. Increasing zinc intake and combating global zinc deficiency requires context-specific strategies and a combination of complementary, evidence-based interventions, including supplementation, food fortification, and food and agricultural solutions such as biofortification, alongside efforts to improve zinc bioavailability. Enhancing dietary zinc content and bioavailability through zinc biofortification is an inclusive nutrition solution that can benefit the most vulnerable individuals and populations affected by inadequate diets to the greatest extent.

Abstract This study examines the relationship between respondents’ vaccine hesitancy, reported media consumption patterns, ideological leanings, and trust in science. A large-scale survey conducted in the US in 2022 (N = 1,646) assessed self-reported COVID-19 vaccination, trust in science, and reported media consumption. Findings show that, regardless of personal ideology, individuals who consumed less conservative media and had a more ideologically diverse media diet were more likely to be fully vaccinated and boosted. Additionally, consuming more conservative media was negatively associated with trust in science, but this relationship was weaker among those with a more ideologically diverse media diet. By incorporating data from an earlier wave of the survey in the summer of 2020, before COVID-19 vaccines were available, we found that a less conservative and more ideologically diverse media diet in 2022 predicted vaccination behavior in 2022, controlling for prior vaccine intentions and media consumption in 2020. A similar survey conducted in the UK in the summer of 2020 paralleled patterns in the US regarding vaccine intentions and media consumption. These results suggest that an ideologically diverse media diet is associated with reduced vaccine hesitancy. Public health initiatives might benefit from encouraging ideologically diverse media consumption.

Abstract Background The Brazilian Policy for Comprehensive Care for People with Rare Diseases was implemented in 2014; however, national epidemiological data on rare diseases (RDs) are scarce and mainly focused on specific disorders. To address this gap, University Hospitals, Reference Services for Neonatal Screening, and Reference Services for Rare Diseases, all of which are public health institutions, established the Brazilian Rare Diseases Network (RARAS) in 2020. The objective of this study was to perform a comprehensive nationwide epidemiological investigation of individuals with RDs in Brazil. This retrospective survey collected data from patients receiving care in 34 healthcare facilities affiliated with RARAS in 2018 and 2019. Results The survey included 12,530 participants with a median age of 15.0 years, with women representing 50.5% of the cohort. Classification according to skin color demonstrated that 5044 (47.4%) participants were admixed. Most had a confirmed diagnosis (63.2%), with a predominance of phenylketonuria (PKU), cystic fibrosis (CF), and acromegaly. Common clinical manifestations included global developmental delay and seizures. The average duration of the diagnostic odyssey was 5.4 years (± 7.9 years). Among the confirmed diagnoses, 52.2% were etiological (biochemical: 42.5%; molecular: 30.9%), while 47.8% were clinical. Prenatal diagnoses accounted for 1.2%. Familial recurrence and consanguinity rates were 21.6% and 6.4%, respectively. Mainstay treatments included drug therapy (55.0%) and rehabilitation (15.6%). The Public Health System funded most diagnoses (84.2%) and treatments (86.7%). Hospitalizations were reported in 44.5% of cases, and the mortality rate was 1.5%, primarily due to motor neuron disease and CF. Conclusion This study marks a pioneering national-level data collection effort for rare diseases in Brazil, offering novel insights to advance the understanding, management, and resource allocation for RDs. It unveils an average diagnostic odyssey of 5.4 years and a higher prevalence of PKU and CF, possibly associated with the specialized services network, which included newborn screening services.

One of the MSMEs developed Batik as a regional product is Rezti's Batik. Rezti's Batik is located in Ambulu, Jember Regency, about 28.4 km from the University of Jember. Increasing the number of consumer orders has made Rezti's Batik production continue to increase. One of the obstacles faced by Rezti's Batik is the process of making Batik which takes a long time because the drying process still relies on heat from the sun, which takes 4-6 hours. The process can also take longer if the rainy season slows the production process's completion. The solution method is the manufacture of appropriate technology in the form of installing a batik cloth dryer. The batik cloth drying installation implementation at Rezti's Batik is a drying system that utilizes heat from the furnace in the sagging process as a heating medium. The designed dryer consists of a stove as a heat generator which will later be distributed with air from the blower so that the hot air will spread evenly throughout the room.

School-wide positive behavior interventions and supports (SWPBIS) is a tiered framework that supports the academic, social, and behavioral needs of students. In this study, we conducted a conceptual replication of Grasley-Boy et al. (2022a) and used a series of two-level linear multilevel analyses to examine the impact of SWPBIS fidelity on 10 exclusionary discipline outcomes for students with disabilities (SWD). Specifically, we compared schools that implemented multiple SWPBIS tiers with fidelity to schools that only implemented Tier 1 with fidelity from a sample of 558 schools in 113 districts in California. Findings indicate a statistically significant decrease in multiple out-of-school suspension categories as well as referrals to law enforcement for SWD in schools that implemented all tiers with fidelity. We provide recommendations for using findings to inform school efforts to reduce exclusionary discipline for SWD.

Multitiered support for professional development (MTS-PD) is emerging as a research-supported, three-tiered framework to support teachers' classroom management skills through targeted training and ongoing coaching. In this study, we applied MTS-PD to increase elementary general education teachers' treatment fidelity of a targeted behavioral support (i.e., self-monitoring) and examined whether increases in treatment fidelity were accompanied by increases in on-task behavior for three focal students who were identified as at-risk of being identified for having an emotional/behavior disorder. Results, which were evaluated in the context of a multiple-probe, single-case research design, indicated that MTS-PD increased teachers' treatment fidelity. However, outcomes were inconsistent with regard to increases in focal students' on-task behavior and decreases in rate of disruptive behavior as a result of increases in treatment fidelity. Results of this study demonstrate that MTS-PD can support teacher implementation of targeted behavioral supports. Practical and research implications are discussed.

BACKGROUND: Zinc-biofortified potatoes have considerable potential to reduce zinc deficiency because of their low levels of phytate, an inhibitor of zinc absorption, and their high consumption, especially in the Andean region of Peru. OBJECTIVES: The purpose of this study was to measure fractional and total zinc absorption from a test meal of biofortified compared with regular potatoes. METHODS: We undertook a single-blinded randomized crossover study (using 67Zn and 70Zn stable isotopes) in which 37 women consumed 500-g biofortified or regular potatoes twice a day. Urine samples were collected to determine fractional and total zinc absorption. RESULTS: The zinc content of the biofortified potato and regular potato was 0.48 (standard deviation [SD]: 0.02) and 0.32 (SD: 0.03) mg/100 g fresh weight, respectively. Mean fractional zinc absorption (FZA) from the biofortified potatoes was lower than from the regular potatoes, 20.8% (SD: 5.4%) and 25.5% (SD: 7.0%), respectively (P < 0.01). However, total zinc absorbed was significantly higher (0.49; SD: 0.13 and 0.40; SD: 0.11 mg/500 g, P < 0.01, respectively). CONCLUSIONS: The results of this study demonstrate that biofortified potatoes provide more absorbable zinc than regular potatoes. Zinc-biofortified potatoes could contribute toward reducing zinc deficiency in populations where potatoes are a staple food. This trial was registered at clinicaltrials.gov as NCT05154500.

Universal screening and progress monitoring are evidence-based practices in early intervention/early childhood special education (EI/ECSE). Individual Growth and Development Indicators (IGDIs) for infants/toddlers are measures that programs can use for universal screening, progress monitoring, intervention decision-making, and accountability. Prior to the COVID-19 pandemic, IGDIs were administered and scored exclusively in person by certified early educators. Because of COVID-19, EI/ECSE practitioners could no longer conduct in-person assessments. We report how two early intervention programs implemented IGDIs using remote protocols that included (a) preparation of parents for IGDI administration at home, (b) session observation by program staff using videoconferencing, and (c) remote coding of the child's performance by program staff when interacting with a parent/caregiver play partner using the standard toy set. The remote protocols are described, and uptake by the programs is compared before and during the pandemic. Equivalence of children's scores from in-person versus remote protocols is reported, as well as caregivers' and program staff's preferences. Implications for remote early childhood services are discussed.

Abstract Biological polymers, such as polysaccharides and polypeptides, offer renewable and biodegradable solutions for a more sustainable future. These polymers comprise natural building blocks, such as amino acids and glycans, which ensure their true environmental benefits at the end of their lifecycle. For example, cellulose is a highly sustainable material with many excellent properties, including renewability, biodegradability, and versatility in its functionality. It can be used in various forms, such as textiles, packaging materials, and building insulation. Here, we studied advanced cellulosic materials produced by blending or creating bi-composites with biomanufactured proteins inspired by squid ring teeth (SRT). Biomanufactured proteins can be synthesized in larger quantities, have a controlled production process, be modified to create desirable variants, and their production can be scaled up or down. Specifically, we engineered recombinant SRT proteins to have high electrostatic charge, induce crystallinity, and provide polar hydroxyl groups, which enhances cellulosic materials’ triboelectric response. The triboelectric voltage of blend triacetate and cellulose fibers increased by 72–108% and 49–57%, respectively, with a protein content of 10% wt. Furthermore, coating proteins on cellulosic fibers to create bi-composite fibers is a highly effective method for doubling (200%) the triboelectric performance. This finding has important implications for developing sustainable triboelectric materials and producing advanced materials using biomanufacturing.

The horizontal-to-vertical spectral ratio (HVSR) method has been used to characterize site-effect parameters that are indispensable in seismic hazard and risk-reduction studies in urban areas and rapid land-use planning. This method is widely used because it is the cheapest and simplest geophysical method for the acquisition and processing stages. In subsequent developments, the HVSR method has been widely used to determine elastic rock parameters, particularly shear wave velocity (vS), through the HVSR curve inversion process. Furthermore, the vS structural model can be used to delineate the presence of complex geological structures, particularly faults and sedimentary basins. Bandar Lampung is a city in Lampung Province with many fault structures and groundwater basins to the south. There are 83 HVSR measurement points around Bandar Lampung for delineating the presence of fault structures and groundwater basins. We produced the HVSR curve from the measurement results and then performed an inversion process using the particle swarm optimization algorithm to obtain vS for the depth profile. Subsequently, from this profile, we produced a two-dimensional (2D) lateral and vertical model. The mean vS value was calculated from all the measurement points, and we found stiff soil layers reaching depths of approximately 5 m, with a value of vS < 330 m/s. A bedrock layer with a velocity exceeding 1250 m/s was visible at a depth of 100 m. Based on the 2D model, the vS structure shows that the city of Bandar Lampung is divided into two zones, with a NW-SE boundary. The north-middle-eastern part of the city consists of harder rocks. This harder rock is characterized by extremely high vS values, starting from a depth of 50 m. In contrast, the south-middle-west exhibits a low-moderate vS anomaly associated with groundwater basins SW of the city. From the 2D vS structural model, fault structures can be found along the city, characterized by a contrast of vS values from low to medium and from medium to high.

School-wide positive behavior interventions and supports (SWPBIS) is widely implemented across the United States. Evidence suggests that SWPBIS, when implemented with fidelity, has a significant and positive impact on schools, including lower suspensions and higher reading and mathematics achievement. A critical component of this research is measuring fidelity of SWPBIS implementation in schools. In this study, we re-evaluated the reliability and validity of a widely used fidelity tool, the Tiered Fidelity Inventory (TFI), within a single-state sample. Using data from 693 schools in the U.S. state of California, we found a hierarchical factor structure based on subscales and tiers fit the data best when controlling for the multilevel nature of the data; however, there was no relation between the latent fidelity variables and changes in suspensions. Implications of these results are discussed, including different approaches to scoring and conceptualizing fidelity of implementation for SWPBIS, along with considerations for future research using the TFI.