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2,230 results on '"Bowman, Robert"'

1. Unidirectional multipulse helicity-independent all-optical switching in [Ni/Pt] based synthetic ferrimagnets

Author

Sait, Connor RJ, Dąbrowski, Maciej, Scott, Jade N, Hendren, William R, Newman, David G, N'Diaye, Alpha T, Klewe, Christoph, Shafer, Padraic, van der Laan, Gerrit, Keatley, Paul S, Bowman, Robert M, and Hicken, Robert J

Subjects
Physical Sciences, Engineering, Nanotechnology, Chemical sciences, Physical sciences
Abstract

Nickel-platinum-based synthetic ferrimagnets (SFi's) are highly tunable and rare-earth-free materials that allow ultrafast all optical control of magnetism to be explored. This study considers a SFi composed of a ferromagnetic [Ni/Pt] multilayer and a ferromagnetic Co layer, separated by an Ir layer that mediates an antiferromagnetic coupling. Helicity-independent all optical switching (HI-AOS) between two antiparallel magnetization states is observed. AOS may be realized at increased temperature through reduction of the thickness of the Pt layers. Switching is unidirectional and has a strong dependence on the applied magnetic field history, which suggests the possible presence of a nanoscale magnetic texture that may be important in controlling AOS in SFi systems.

Published
2024

3. Mapping genotypes to chromatin accessibility profiles in single cells

Author

Izzo, Franco, Myers, Robert M., Ganesan, Saravanan, Mekerishvili, Levan, Kottapalli, Sanjay, Prieto, Tamara, Eton, Elliot O., Botella, Theo, Dunbar, Andrew J., Bowman, Robert L., Sotelo, Jesus, Potenski, Catherine, Mimitou, Eleni P., Stahl, Maximilian, El Ghaity-Beckley, Sebastian, Arandela, JoAnn, Raviram, Ramya, Choi, Daniel C., Hoffman, Ronald, Chaligné, Ronan, Abdel-Wahab, Omar, Smibert, Peter, Ghobrial, Irene M., Scandura, Joseph M., Marcellino, Bridget, Levine, Ross L., and Landau, Dan A.

Published
2024
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6. Optical properties of Au-Hf thin films

Author

Littlehailes, Hugh, Hendren, William R., Bowman, Robert M., and Huang, Fumin

Subjects
Condensed Matter - Materials Science, Physics - Applied Physics
Abstract

The optical properties of thin films of intermetallic Au$_{3}$Hf were experimentally investigated for the first time, which display clear plasmonic properties in the optical and near infrared region with negative permittivity. In contrast to similar alloys, such as films of Au$_{3}$Zr, the films express more negative $\epsilon'$ values and lower $\epsilon''$ values across most of the wavelengths (370-1570 nm) investigated. The Au$_{3}$Hf films were fabricated by DC magnetron sputtering at a range of deposition temperatures, from room temperature to 415$^{o}$C, and annealed at different vacuum levels. The films mostly formed as a combination of Au$_{3}$Hf, Au$_{2}$Hf and Au$_{4}$Hf phases when deposited below 400$^{o}$C, and exclusively Au$_{3}$Hf phase at above 400$^{o}$C, indicating key conditions for isolating this phase. The films were stable when annealed at 10$^{-8}$ Torr, but when annealed again at 10$^{-6}$ Torr the films oxidised and changed into a mix of Au- Hf phases, suggesting resistance to oxidization may be an issue for un-encapsulated applications at elevated temperatures., Comment: 19 pages, including references, plus 3 pages of supplementary material. 8 figures and 1 table in main text, 1 figure and 1 table in supplementary material

Published
2022

8. Searching for refractory plasmonic materials: the structural and optical properties of Au$_{3}$Zr intermetallic thin films

Author

Littlehailes, Hugh, Hendren, William R., Drakeley, Stacey, Bowman, Robert M., and Huang, Fumin

Subjects
Physics - Applied Physics, Condensed Matter - Materials Science
Abstract

Optical properties of refractory intermetallic thin films of Au$_{3}$Zr were experimentally investigated for the first time, which show distinctive plasmonic properties in the visible and near infrared region. The films were fabricated through DC magnetron sputtering at various deposition temperature ranging from room temperature to 427$^{o}$C and annealed at different vacuum levels. Both the structural and optical properties are found to be critically dependent on deposition temperature and anneal conditions. Films deposited between 205-320$^{o}$C are shown to exhibit lower negative permittivity and better thermal stability, which could be linked to specific crystalline orientations. The films are stable when annealed at 10$^{-8}$ Torr, but are partially oxidized when annealed at 10$^{-6}$ Torr, suggesting oxidization could be a restricting issue for high-temperature applications in ambient environment., Comment: 12 pages, plus 3 pages in attached supplementary information. 7 figures in main text, plus 1 table and 1 figure in attached supplementary information

Published
2021

9. Single-cell mutation analysis of clonal evolution in myeloid malignancies

Author

Miles, Linde A, Bowman, Robert L, Merlinsky, Tiffany R, Csete, Isabelle S, Ooi, Aik T, Durruthy-Durruthy, Robert, Bowman, Michael, Famulare, Christopher, Patel, Minal A, Mendez, Pedro, Ainali, Chrysanthi, Demaree, Benjamin, Delley, Cyrille L, Abate, Adam R, Manivannan, Manimozhi, Sahu, Sombeet, Goldberg, Aaron D, Bolton, Kelly L, Zehir, Ahmet, Rampal, Raajit, Carroll, Martin P, Meyer, Sara E, Viny, Aaron D, and Levine, Ross L

Subjects
Biological Sciences, Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Biotechnology, Rare Diseases, Genetics, Clinical Research, Hematology, Cancer, Human Genome, 2.1 Biological and endogenous factors, Aetiology, Cell Separation, Clone Cells, DNA Mutational Analysis, Humans, Immunophenotyping, Mutation, Myeloproliferative Disorders, Single-Cell Analysis, General Science & Technology
Abstract

Myeloid malignancies, including acute myeloid leukaemia (AML), arise from the expansion of haematopoietic stem and progenitor cells that acquire somatic mutations. Bulk molecular profiling has suggested that mutations are acquired in a stepwise fashion: mutant genes with high variant allele frequencies appear early in leukaemogenesis, and mutations with lower variant allele frequencies are thought to be acquired later1-3. Although bulk sequencing can provide information about leukaemia biology and prognosis, it cannot distinguish which mutations occur in the same clone(s), accurately measure clonal complexity, or definitively elucidate the order of mutations. To delineate the clonal framework of myeloid malignancies, we performed single-cell mutational profiling on 146 samples from 123 patients. Here we show that AML is dominated by a small number of clones, which frequently harbour co-occurring mutations in epigenetic regulators. Conversely, mutations in signalling genes often occur more than once in distinct subclones, consistent with increasing clonal diversity. We mapped clonal trajectories for each sample and uncovered combinations of mutations that synergized to promote clonal expansion and dominance. Finally, we combined protein expression with mutational analysis to map somatic genotype and clonal architecture with immunophenotype. Our findings provide insights into the pathogenesis of myeloid transformation and how clonal complexity evolves with disease progression.

Published
2020

10. CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis

Author

Dunbar, Andrew J., Kim, Dongjoo, Lu, Min, Farina, Mirko, Bowman, Robert L., Yang, Julie L., Park, Young, Karzai, Abdul, Xiao, Wenbin, Zaroogian, Zach, O’Connor, Kavi, Mowla, Shoron, Gobbo, Francesca, Verachi, Paola, Martelli, Fabrizio, Sarli, Giuseppe, Xia, Lijuan, Elmansy, Nada, Kleppe, Maria, Chen, Zhuo, Xiao, Yang, McGovern, Erin, Snyder, Jenna, Krishnan, Aishwarya, Hill, Corrine, Cordner, Keith, Zouak, Anouar, Salama, Mohamed E., Yohai, Jayden, Tucker, Eric, Chen, Jonathan, Zhou, Jing, McConnell, Timothy, Migliaccio, Anna R., Koche, Richard, Rampal, Raajit, Fan, Rong, Levine, Ross L., and Hoffman, Ronald

Published
2023
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12. Hunting micrometer-sized graphene flakes on gold substrate

Author

Katzen, Joel M., Velický, Matěj, Huang, Yuefeng, Drakeley, Stacey, Hendren, William, Bowman, Robert M., Cai, Qiran, Chen, Ying, Li, Lu Hua, and Huang, Fumin

Subjects
Condensed Matter - Materials Science
Abstract

Gold is widely used as the substrate material in many graphene devices, due to its superior optoelectronic properties and chemical stability. However, there has been little experimental investigation on the optical contrast of graphene films on Au substrates. Here we report accurate measurement of the optical contrast spectra of few-layer graphene flakes on bulk Au. We used a high-resolution optical microscopy with a 100x magnification objective, accurately determining the thickness of flakes as small as one micrometer in lateral size, which are highly desired in many applications. The results are in excellent agreement with theoretical calculations and confirmed by Raman and AFM measurements. Furthermore, we demonstrate that the optical contrast spectroscopy is sensitive enough to detect the adsorption of a sub-monolayer airborne hydrocarbon molecules, which can reveal whether graphene is con-taminated and opens the opportunity to develop miniaturized and ultrasensitive molecular sensors.

Published
2018

15. Supplementary Figure S1 from Jak2V617F Reversible Activation Shows Its Essential Requirement in Myeloproliferative Neoplasms

Author

Dunbar, Andrew J., primary, Bowman, Robert L., primary, Park, Young C., primary, O'Connor, Kavi, primary, Izzo, Franco, primary, Myers, Robert M., primary, Karzai, Abdul, primary, Zaroogian, Zachary, primary, Kim, Won Jun, primary, Fernández-Maestre, Inés, primary, Waarts, Michael R., primary, Nazir, Abbas, primary, Xiao, Wenbin, primary, Codilupi, Tamara, primary, Brodsky, Max, primary, Farina, Mirko, primary, Cai, Louise, primary, Cai, Sheng F., primary, Wang, Benjamin, primary, An, Wenbin, primary, Yang, Julie L., primary, Mowla, Shoron, primary, Eisman, Shira E., primary, Hanasoge Somasundara, Amritha Varshini, primary, Glass, Jacob L., primary, Mishra, Tanmay, primary, Houston, Remie, primary, Guzzardi, Emily, primary, Martinez Benitez, Anthony R., primary, Viny, Aaron D., primary, Koche, Richard P., primary, Meyer, Sara C., primary, Landau, Dan A., primary, and Levine, Ross L., primary

Published
2024
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16. Supplementary Table S2 from Jak2V617F Reversible Activation Shows Its Essential Requirement in Myeloproliferative Neoplasms

Author

Dunbar, Andrew J., primary, Bowman, Robert L., primary, Park, Young C., primary, O'Connor, Kavi, primary, Izzo, Franco, primary, Myers, Robert M., primary, Karzai, Abdul, primary, Zaroogian, Zachary, primary, Kim, Won Jun, primary, Fernández-Maestre, Inés, primary, Waarts, Michael R., primary, Nazir, Abbas, primary, Xiao, Wenbin, primary, Codilupi, Tamara, primary, Brodsky, Max, primary, Farina, Mirko, primary, Cai, Louise, primary, Cai, Sheng F., primary, Wang, Benjamin, primary, An, Wenbin, primary, Yang, Julie L., primary, Mowla, Shoron, primary, Eisman, Shira E., primary, Hanasoge Somasundara, Amritha Varshini, primary, Glass, Jacob L., primary, Mishra, Tanmay, primary, Houston, Remie, primary, Guzzardi, Emily, primary, Martinez Benitez, Anthony R., primary, Viny, Aaron D., primary, Koche, Richard P., primary, Meyer, Sara C., primary, Landau, Dan A., primary, and Levine, Ross L., primary

Published
2024
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17. Data from Jak2V617F Reversible Activation Shows Its Essential Requirement in Myeloproliferative Neoplasms

Author

Dunbar, Andrew J., primary, Bowman, Robert L., primary, Park, Young C., primary, O'Connor, Kavi, primary, Izzo, Franco, primary, Myers, Robert M., primary, Karzai, Abdul, primary, Zaroogian, Zachary, primary, Kim, Won Jun, primary, Fernández-Maestre, Inés, primary, Waarts, Michael R., primary, Nazir, Abbas, primary, Xiao, Wenbin, primary, Codilupi, Tamara, primary, Brodsky, Max, primary, Farina, Mirko, primary, Cai, Louise, primary, Cai, Sheng F., primary, Wang, Benjamin, primary, An, Wenbin, primary, Yang, Julie L., primary, Mowla, Shoron, primary, Eisman, Shira E., primary, Hanasoge Somasundara, Amritha Varshini, primary, Glass, Jacob L., primary, Mishra, Tanmay, primary, Houston, Remie, primary, Guzzardi, Emily, primary, Martinez Benitez, Anthony R., primary, Viny, Aaron D., primary, Koche, Richard P., primary, Meyer, Sara C., primary, Landau, Dan A., primary, and Levine, Ross L., primary

Published
2024
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18. Jak2V617F Reversible Activation Shows Its Essential Requirement in Myeloproliferative Neoplasms

Author

Dunbar, Andrew J., primary, Bowman, Robert L., additional, Park, Young C., additional, O'Connor, Kavi, additional, Izzo, Franco, additional, Myers, Robert M., additional, Karzai, Abdul, additional, Zaroogian, Zachary, additional, Kim, Won Jun, additional, Fernández-Maestre, Inés, additional, Waarts, Michael R., additional, Nazir, Abbas, additional, Xiao, Wenbin, additional, Codilupi, Tamara, additional, Brodsky, Max, additional, Farina, Mirko, additional, Cai, Louise, additional, Cai, Sheng F., additional, Wang, Benjamin, additional, An, Wenbin, additional, Yang, Julie L., additional, Mowla, Shoron, additional, Eisman, Shira E., additional, Hanasoge Somasundara, Amritha Varshini, additional, Glass, Jacob L., additional, Mishra, Tanmay, additional, Houston, Remie, additional, Guzzardi, Emily, additional, Martinez Benitez, Anthony R., additional, Viny, Aaron D., additional, Koche, Richard P., additional, Meyer, Sara C., additional, Landau, Dan A., additional, and Levine, Ross L., additional

Published
2024
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19. Compensatory CSF2-driven macrophage activation promotes adaptive resistance to CSF1R inhibition in breast-to-brain metastasis

Author

Klemm, Florian, Möckl, Aylin, Salamero-Boix, Anna, Alekseeva, Tijna, Schäffer, Alexander, Schulz, Michael, Niesel, Katja, Maas, Roeltje R., Groth, Marie, Elie, Benelita T., Bowman, Robert L., Hegi, Monika E., Daniel, Roy T., Zeiner, Pia S., Zinke, Jenny, Harter, Patrick N., Plate, Karl H., Joyce, Johanna A., and Sevenich, Lisa

Published
2021
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21. Plasmacytoid dendritic cell expansion defines a distinct subset of RUNX1-mutated acute myeloid leukemia

Author

Xiao, Wenbin, Chan, Alexander, Waarts, Michael R., Mishra, Tanmay, Liu, Ying, Cai, Sheng F., Yao, Jinjuan, Gao, Qi, Bowman, Robert L., Koche, Richard P., Csete, Isabelle S., DelGaudio, Nicole L., Derkach, Andriy, Baik, Jeeyeon, Yanis, Sophia, Famulare, Christopher A., Patel, Minal, Arcila, Maria E., Stahl, Maximilian, Rampal, Raajit K., Tallman, Martin S., Zhang, Yanming, Dogan, Ahmet, Goldberg, Aaron D., Roshal, Mikhail, and Levine, Ross L.

Published
2021
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22. Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis

Author

Kleppe, Maria, Spitzer, Matthew H, Li, Sheng, Hill, Corinne E, Dong, Lauren, Papalexi, Efthymia, De Groote, Sofie, Bowman, Robert L, Keller, Matthew, Koppikar, Priya, Rapaport, Franck T, Teruya-Feldstein, Julie, Gandara, Jorge, Mason, Christopher E, Nolan, Garry P, and Levine, Ross L

Subjects
Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Biological Sciences, Stem Cell Research - Nonembryonic - Non-Human, Hematology, Regenerative Medicine, Stem Cell Research, 1.1 Normal biological development and functioning, Underpinning research, Aetiology, 2.1 Biological and endogenous factors, Inflammatory and immune system, Alleles, Animals, Bone Marrow Transplantation, Cell Cycle, Cell Differentiation, Enzyme Activation, Gene Expression Regulation, Hematopoiesis, Hematopoietic Stem Cells, Immunosuppression Therapy, Interferon Type I, Interleukin-3, Janus Kinase 1, Mice, Knockout, Myeloid Cells, Signal Transduction, Stress, Physiological, Jak1, cytokine signaling, hematopoietic stem cells, stress hematopoiesis, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences
Abstract

JAK1 is a critical effector of pro-inflammatory cytokine signaling and plays important roles in immune function, while abnormal JAK1 activity has been linked to immunological and neoplastic diseases. Specific functions of JAK1 in the context of hematopoiesis, and specifically within hematopoietic stem cells (HSCs), have not clearly been delineated. Here, we show that conditional Jak1 loss in HSCs reduces their self-renewal and markedly alters lymphoid/myeloid differentiation in vivo. Jak1-deficient HSCs exhibit decreased competitiveness in vivo and are unable to rescue hematopoiesis in the setting of myelosuppression. They exhibit increased quiescence, an inability to enter the cell cycle in response to hematopoietic stress, and a marked reduction in cytokine sensing, including in response to type I interferons and IL-3. Moreover, Jak1 loss is not fully rescued by expression of a constitutively active Jak2 allele. Together, these data highlight an essential role for Jak1 in HSC homeostasis and stress responses.

Published
2017

23. Synthetic biological circuit tested in spaceflight

Author

Kitto, Rebekah Z., Dhillon, Yadvender, Bevington, James, Horne, Mera, Giegé, Philippe, Drouard, Laurence, Heintz, Dimitri, Villette, Claire, Corre, Nicolas, Arrivé, Mathilde, Manefield, Michael J, Bowman, Robert, Favier, Jean-Jacques, Osborne, Barnaby, Welch, Chris, McKay, Christopher P., and Hammond, Ming C.

Published
2021
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25. Observation of Room Temperature Exchange Cavity Magnon‐Polaritons in Metallic Thin Films.

Author

Smith, Mawgan A., Lafferty, Adam L., Joseph, Alban, McMaster, Matthew R., Scott, Jade N., Hendren, William R., Bowman, Robert M., Weides, Martin P., and Macêdo, Rair

Subjects
METALLIC thin films, MAGNETIC insulators, MAGNETIC films, SPIN waves, MAGNONS, STANDING waves
Abstract

Cavity magnonics has become an intriguing field due to its potential to enable next‐generation technologies centered around controlling information exchange in hybrid resonant systems. Investigating the tunability of magnon‐photon coupling is key to advancing the field. Here, the observation of coupling between the first order magnon mode in a metallic thin film with a cavity photon mode is reported. An electromagnetic perturbation theory that takes account of perpendicular standing spin waves and their respective dissipation is utilized to estimate the coupling strength. The metallic thin film exhibits notably lower dissipation for the higher‐order magnon mode, which is not observed in a thin film magnetic insulator. As such, and given that metallic Kittel magnons typically exhibit lower coherence times than their insulator counterparts, the excitation and coupling to specific higher order modes could lengthen these times compared to previous observations, which may be useful for future integration into quantum devices. [ABSTRACT FROM AUTHOR]

Published
2024
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26. Deconvoluting hepatic processing of carbon nanotubes.

Author

Alidori, Simone, Bowman, Robert L, Yarilin, Dmitry, Romin, Yevgeniy, Barlas, Afsar, Mulvey, J Justin, Fujisawa, Sho, Xu, Ke, Ruggiero, Alessandro, Riabov, Vladimir, Thorek, Daniel LJ, Ulmert, Hans David S, Brea, Elliott J, Behling, Katja, Kzhyshkowska, Julia, Manova-Todorova, Katia, Scheinberg, David A, and McDevitt, Michael R

Subjects
Liver, Animals, Mice, Inbred BALB C, Macaca fascicularis, Mice, Nanotubes, Carbon, Materials Testing, Endocytosis, Pharmacokinetics, Female, Male, Inbred BALB C, Nanotubes, Carbon
Abstract

Single-wall carbon nanotubes present unique opportunities for drug delivery, but have not advanced into the clinic. Differential nanotube accretion and clearance from critical organs have been observed, but the mechanism not fully elucidated. The liver has a complex cellular composition that regulates a range of metabolic functions and coincidently accumulates most particulate drugs. Here we provide the unexpected details of hepatic processing of covalently functionalized nanotubes including receptor-mediated endocytosis, cellular trafficking and biliary elimination. Ammonium-functionalized fibrillar nanocarbon is found to preferentially localize in the fenestrated sinusoidal endothelium of the liver but not resident macrophages. Stabilin receptors mediate the endocytic clearance of nanotubes. Biocompatibility is evidenced by the absence of cell death and no immune cell infiltration. Towards clinical application of this platform, nanotubes were evaluated for the first time in non-human primates. The pharmacologic profile in cynomolgus monkeys is equivalent to what was reported in mice and suggests that nanotubes should behave similarly in humans.

Published
2016

28. Deep generative model deciphers derailed trajectories in acute myeloid leukemia

Author

Nazaret, Achille, primary, Fan, Joy Linyue, additional, Lavallee, Vincent-Philippe, additional, Cornish, Andrew E., additional, Kiseliovas, Vaidotas, additional, Masilionis, Ignas, additional, Chun, Jaeyoung, additional, Bowman, Robert L., additional, Eisman, Shira E., additional, Wang, James, additional, Shi, Lingting, additional, Levine, Ross L., additional, Mazutis, Linas, additional, Blei, David, additional, Pe'er, Dana, additional, and Azizi, Elham, additional

Published
2023
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29. Mutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity

Author

Majeti, Ravi, primary, Schwede, Matthew, additional, Jahn, Katharina, additional, Kuipers, Jack, additional, Miles, Linde, additional, Bowman, Robert, additional, Robinson, Troy, additional, Furudate, Ken, additional, Uryu, Hidetaka, additional, Tanaka, Tomoyuki, additional, Sasaki, Yuya, additional, Ediriwickrema, Asiri, additional, Benard, Brooks, additional, Gentles, Andrew, additional, Levine, Ross, additional, Beerenwinkel, Niko, additional, and Takahashi, Koichi, additional

Published
2023
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31. Single-cell genotypic and phenotypic analysis of measurable residual disease in acute myeloid leukemia

Author

Robinson, Troy M., primary, Bowman, Robert L., additional, Persaud, Sonali, additional, Liu, Ying, additional, Neigenfind, Rosemary, additional, Gao, Qi, additional, Zhang, Jingping, additional, Sun, Xiaotian, additional, Miles, Linde A., additional, Cai, Sheng F., additional, Sciambi, Adam, additional, Llanso, Aaron, additional, Famulare, Christopher, additional, Goldberg, Aaron, additional, Dogan, Ahmet, additional, Roshal, Mikhail, additional, Levine, Ross L., additional, and Xiao, Wenbin, additional

Published
2023
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34. Hematopoietic-specific heterozygous loss of Dnmt3a exacerbates colitis-associated colon cancer

Author

Feng, Yang, primary, Yuan, Qingchen, additional, Newsome, Rachel C., additional, Robinson, Troy, additional, Bowman, Robert L., additional, Zuniga, Ashley N., additional, Hall, Kendra N., additional, Bernsten, Cassandra M., additional, Shabashvili, Daniil E., additional, Krajcik, Kathryn I., additional, Gunaratne, Chamara, additional, Zaroogian, Zachary J., additional, Venugopal, Kartika, additional, Casellas Roman, Heidi L., additional, Levine, Ross L., additional, Chatila, Walid K., additional, Yaeger, Rona, additional, Riva, Alberto, additional, Jobin, Christian, additional, Kopinke, Daniel, additional, Avram, Dorina, additional, and Guryanova, Olga A., additional

Published
2023
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37. All optical switching in transition metal synthetic ferrimagnetic multilayer systems with enhanced interlayer exchange coupling

Author

Sait, Connor R. J., primary, Dąbrowski, Maciej, additional, Scott, Jade N., additional, Hendren, William R., additional, Newman, David G., additional, N’Diaye, Alpha T., additional, Klewe, Christoph, additional, Shafer, Padraic, additional, van der Laan, Gerrit, additional, Keatley, Paul S., additional, Bowman, Robert M., additional, and Hicken, Robert J., additional

Published
2023
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38. Abstract A49: Characterizing the order of mutation acquisition in acute myeloid leukemia using large-scale single-cell sequencing

Author

Schwede, Matthew, primary, Jahn, Katharina, additional, Miles, Linde A, additional, Bowman, Robert L, additional, Kuipers, Jack, additional, Robinson, Troy M, additional, Ediriwickrema, Asiri, additional, Gentles, Andrew J, additional, Levine, Ross, additional, Beerenwinkel, Niko, additional, Takahashi, Koichi, additional, and Majeti, Ravindra, additional

Published
2023
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40. Integrating Individual and Social Contexts into Self-Reflection Technologies

Author

Bhattacharjee, Ananya, primary, Kulzhabayeva, Dana, additional, Reza, Mohi, additional, Kumar, Harsh, additional, Seong, Eunchae, additional, Wu, Xuening, additional, Rifat, Mohammad Rashidujjaman, additional, Bowman, Robert, additional, Kornfield, Rachel, additional, Mariakakis, Alex, additional, Ahmed, Syed Ishtiaque, additional, De Choudhury, Munmun, additional, Doherty, Gavin, additional, Czerwinski, Mary P, additional, and Williams, Joseph Jay, additional

Published
2023
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41. Table S1 from Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers

Author

Glass, Jacob L., primary, Hassane, Duane, primary, Wouters, Bas J., primary, Kunimoto, Hiroyoshi, primary, Avellino, Roberto, primary, Garrett-Bakelman, Francine E., primary, Guryanova, Olga A., primary, Bowman, Robert, primary, Redlich, Shira, primary, Intlekofer, Andrew M., primary, Meydan, Cem, primary, Qin, Tingting, primary, Fall, Mame, primary, Alonso, Alicia, primary, Guzman, Monica L., primary, Valk, Peter J.M., primary, Thompson, Craig B., primary, Levine, Ross, primary, Elemento, Olivier, primary, Delwel, Ruud, primary, Melnick, Ari, primary, and Figueroa, Maria E., primary

Published
2023
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42. Table S3 (part 3) from Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers

Author

Glass, Jacob L., primary, Hassane, Duane, primary, Wouters, Bas J., primary, Kunimoto, Hiroyoshi, primary, Avellino, Roberto, primary, Garrett-Bakelman, Francine E., primary, Guryanova, Olga A., primary, Bowman, Robert, primary, Redlich, Shira, primary, Intlekofer, Andrew M., primary, Meydan, Cem, primary, Qin, Tingting, primary, Fall, Mame, primary, Alonso, Alicia, primary, Guzman, Monica L., primary, Valk, Peter J.M., primary, Thompson, Craig B., primary, Levine, Ross, primary, Elemento, Olivier, primary, Delwel, Ruud, primary, Melnick, Ari, primary, and Figueroa, Maria E., primary

Published
2023
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43. Data from Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers

Author

Glass, Jacob L., primary, Hassane, Duane, primary, Wouters, Bas J., primary, Kunimoto, Hiroyoshi, primary, Avellino, Roberto, primary, Garrett-Bakelman, Francine E., primary, Guryanova, Olga A., primary, Bowman, Robert, primary, Redlich, Shira, primary, Intlekofer, Andrew M., primary, Meydan, Cem, primary, Qin, Tingting, primary, Fall, Mame, primary, Alonso, Alicia, primary, Guzman, Monica L., primary, Valk, Peter J.M., primary, Thompson, Craig B., primary, Levine, Ross, primary, Elemento, Olivier, primary, Delwel, Ruud, primary, Melnick, Ari, primary, and Figueroa, Maria E., primary

Published
2023
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44. Data from Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins

Author

Zhang, Maomao, primary, Di Martino, Julie S., primary, Bowman, Robert L., primary, Campbell, Nathaniel R., primary, Baksh, Sanjeethan C., primary, Simon-Vermot, Theresa, primary, Kim, Isabella S., primary, Haldeman, Pearce, primary, Mondal, Chandrani, primary, Yong-Gonzales, Vladimir, primary, Abu-Akeel, Mohsen, primary, Merghoub, Taha, primary, Jones, Drew R., primary, Zhu, Xiphias Ge, primary, Arora, Arshi, primary, Ariyan, Charlotte E., primary, Birsoy, Kivanç, primary, Wolchok, Jedd D., primary, Panageas, Katherine S., primary, Hollmann, Travis, primary, Bravo-Cordero, Jose Javier, primary, and White, Richard M., primary

Published
2023
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45. Supplemental Table 3 from Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins

Author

Zhang, Maomao, primary, Di Martino, Julie S., primary, Bowman, Robert L., primary, Campbell, Nathaniel R., primary, Baksh, Sanjeethan C., primary, Simon-Vermot, Theresa, primary, Kim, Isabella S., primary, Haldeman, Pearce, primary, Mondal, Chandrani, primary, Yong-Gonzales, Vladimir, primary, Abu-Akeel, Mohsen, primary, Merghoub, Taha, primary, Jones, Drew R., primary, Zhu, Xiphias Ge, primary, Arora, Arshi, primary, Ariyan, Charlotte E., primary, Birsoy, Kivanç, primary, Wolchok, Jedd D., primary, Panageas, Katherine S., primary, Hollmann, Travis, primary, Bravo-Cordero, Jose Javier, primary, and White, Richard M., primary

Published
2023
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46. Data from PRMT5 Inhibition Modulates E2F1 Methylation and Gene-Regulatory Networks Leading to Therapeutic Efficacy in JAK2V617F-Mutant MPN

Author

Pastore, Friederike, primary, Bhagwat, Neha, primary, Pastore, Alessandro, primary, Radzisheuskaya, Aliaksandra, primary, Karzai, Abdul, primary, Krishnan, Aishwarya, primary, Li, Bing, primary, Bowman, Robert L., primary, Xiao, Wenbin, primary, Viny, Aaron D., primary, Zouak, Anouar, primary, Park, Young C., primary, Cordner, Keith B., primary, Braunstein, Stephanie, primary, Maag, Jesper L., primary, Grego, Alexander, primary, Mehta, Jaanvi, primary, Wang, Min, primary, Lin, Hong, primary, Durham, Benjamin H., primary, Koche, Richard P., primary, Rampal, Raajit K., primary, Helin, Kristian, primary, Scherle, Peggy, primary, Vaddi, Kris, primary, and Levine, Ross L., primary

Published
2023
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47. Supplementary figures from Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins

Author

Zhang, Maomao, primary, Di Martino, Julie S., primary, Bowman, Robert L., primary, Campbell, Nathaniel R., primary, Baksh, Sanjeethan C., primary, Simon-Vermot, Theresa, primary, Kim, Isabella S., primary, Haldeman, Pearce, primary, Mondal, Chandrani, primary, Yong-Gonzales, Vladimir, primary, Abu-Akeel, Mohsen, primary, Merghoub, Taha, primary, Jones, Drew R., primary, Zhu, Xiphias Ge, primary, Arora, Arshi, primary, Ariyan, Charlotte E., primary, Birsoy, Kivanç, primary, Wolchok, Jedd D., primary, Panageas, Katherine S., primary, Hollmann, Travis, primary, Bravo-Cordero, Jose Javier, primary, and White, Richard M., primary

Published
2023
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48. Table S3 (part 1) from Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers

Author

Glass, Jacob L., primary, Hassane, Duane, primary, Wouters, Bas J., primary, Kunimoto, Hiroyoshi, primary, Avellino, Roberto, primary, Garrett-Bakelman, Francine E., primary, Guryanova, Olga A., primary, Bowman, Robert, primary, Redlich, Shira, primary, Intlekofer, Andrew M., primary, Meydan, Cem, primary, Qin, Tingting, primary, Fall, Mame, primary, Alonso, Alicia, primary, Guzman, Monica L., primary, Valk, Peter J.M., primary, Thompson, Craig B., primary, Levine, Ross, primary, Elemento, Olivier, primary, Delwel, Ruud, primary, Melnick, Ari, primary, and Figueroa, Maria E., primary

Published
2023
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49. Supplemental Table 5 from Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins

Author

Zhang, Maomao, primary, Di Martino, Julie S., primary, Bowman, Robert L., primary, Campbell, Nathaniel R., primary, Baksh, Sanjeethan C., primary, Simon-Vermot, Theresa, primary, Kim, Isabella S., primary, Haldeman, Pearce, primary, Mondal, Chandrani, primary, Yong-Gonzales, Vladimir, primary, Abu-Akeel, Mohsen, primary, Merghoub, Taha, primary, Jones, Drew R., primary, Zhu, Xiphias Ge, primary, Arora, Arshi, primary, Ariyan, Charlotte E., primary, Birsoy, Kivanç, primary, Wolchok, Jedd D., primary, Panageas, Katherine S., primary, Hollmann, Travis, primary, Bravo-Cordero, Jose Javier, primary, and White, Richard M., primary

Published
2023
Full Text
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50. Supplemental Table 4 from Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins

Author

Zhang, Maomao, primary, Di Martino, Julie S., primary, Bowman, Robert L., primary, Campbell, Nathaniel R., primary, Baksh, Sanjeethan C., primary, Simon-Vermot, Theresa, primary, Kim, Isabella S., primary, Haldeman, Pearce, primary, Mondal, Chandrani, primary, Yong-Gonzales, Vladimir, primary, Abu-Akeel, Mohsen, primary, Merghoub, Taha, primary, Jones, Drew R., primary, Zhu, Xiphias Ge, primary, Arora, Arshi, primary, Ariyan, Charlotte E., primary, Birsoy, Kivanç, primary, Wolchok, Jedd D., primary, Panageas, Katherine S., primary, Hollmann, Travis, primary, Bravo-Cordero, Jose Javier, primary, and White, Richard M., primary

Published
2023
Full Text
View/download PDF

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