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1. Integrating deep learning CT-scan model, biological and clinical variables to predict severity of COVID-19 patients

Author

Lassau, Nathalie, Ammari, Samy, Chouzenoux, Emilie, Gortais, Hugo, Herent, Paul, Devilder, Matthieu, Soliman, Samer, Meyrignac, Olivier, Talabard, Marie-Pauline, Lamarque, Jean-Philippe, Dubois, Remy, Loiseau, Nicolas, Trichelair, Paul, Bendjebbar, Etienne, Garcia, Gabriel, Balleyguier, Corinne, Merad, Mansouria, Stoclin, Annabelle, Jegou, Simon, Griscelli, Franck, Tetelboum, Nicolas, Li, Yingping, Verma, Sagar, Terris, Matthieu, Dardouri, Tasnim, Gupta, Kavya, Neacsu, Ana, Chemouni, Frank, Sefta, Meriem, Jehanno, Paul, Bousaid, Imad, Boursin, Yannick, Planchet, Emmanuel, Azoulay, Mikael, Dachary, Jocelyn, Brulport, Fabien, Gonzalez, Adrian, Dehaene, Olivier, Schiratti, Jean-Baptiste, Schutte, Kathryn, Pesquet, Jean-Christophe, Talbot, Hugues, Pronier, Elodie, Wainrib, Gilles, Clozel, Thomas, Barlesi, Fabrice, Bellin, Marie-France, and Blum, Michael G. B.

Published
2021
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2. Supplementary Table S2 from Frequent Homologous Recombination Deficiency in High-grade Endometrial Carcinomas

Author

de Jonge, Marthe M., primary, Auguste, Aurélie, primary, van Wijk, Lise M., primary, Schouten, Philip C., primary, Meijers, Matty, primary, ter Haar, Natalja T., primary, Smit, Vincent T.H.B.M., primary, Nout, Remi A., primary, Glaire, Mark A., primary, Church, David N., primary, Vrieling, Harry, primary, Job, Bastien, primary, Boursin, Yannick, primary, de Kroon, Cor D., primary, Rouleau, Etienne, primary, Leary, Alexandra, primary, Vreeswijk, Maaike P.G., primary, and Bosse, Tjalling, primary

Published
2023
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3. Data from Improving the Performance of Somatic Mutation Identification by Recovering Circulating Tumor DNA Mutations

Author

Fu, Yu, primary, Jovelet, Cécile, primary, Filleron, Thomas, primary, Pedrero, Marion, primary, Motté, Nelly, primary, Boursin, Yannick, primary, Luo, Yufei, primary, Massard, Christophe, primary, Campone, Mario, primary, Levy, Christelle, primary, Diéras, Véronique, primary, Bachelot, Thomas, primary, Garrabey, Julie, primary, Soria, Jean-Charles, primary, Lacroix, Ludovic, primary, André, Fabrice, primary, and Lefebvre, Celine, primary

Published
2023
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4. Supplementary Figure S2 from Frequent Homologous Recombination Deficiency in High-grade Endometrial Carcinomas

Author

de Jonge, Marthe M., primary, Auguste, Aurélie, primary, van Wijk, Lise M., primary, Schouten, Philip C., primary, Meijers, Matty, primary, ter Haar, Natalja T., primary, Smit, Vincent T.H.B.M., primary, Nout, Remi A., primary, Glaire, Mark A., primary, Church, David N., primary, Vrieling, Harry, primary, Job, Bastien, primary, Boursin, Yannick, primary, de Kroon, Cor D., primary, Rouleau, Etienne, primary, Leary, Alexandra, primary, Vreeswijk, Maaike P.G., primary, and Bosse, Tjalling, primary

Published
2023
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5. Supplementary Table 1 from Improving the Performance of Somatic Mutation Identification by Recovering Circulating Tumor DNA Mutations

Author

Fu, Yu, primary, Jovelet, Cécile, primary, Filleron, Thomas, primary, Pedrero, Marion, primary, Motté, Nelly, primary, Boursin, Yannick, primary, Luo, Yufei, primary, Massard, Christophe, primary, Campone, Mario, primary, Levy, Christelle, primary, Diéras, Véronique, primary, Bachelot, Thomas, primary, Garrabey, Julie, primary, Soria, Jean-Charles, primary, Lacroix, Ludovic, primary, André, Fabrice, primary, and Lefebvre, Celine, primary

Published
2023
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6. Supplementary Figure 2 from Improving the Performance of Somatic Mutation Identification by Recovering Circulating Tumor DNA Mutations

Author

Fu, Yu, primary, Jovelet, Cécile, primary, Filleron, Thomas, primary, Pedrero, Marion, primary, Motté, Nelly, primary, Boursin, Yannick, primary, Luo, Yufei, primary, Massard, Christophe, primary, Campone, Mario, primary, Levy, Christelle, primary, Diéras, Véronique, primary, Bachelot, Thomas, primary, Garrabey, Julie, primary, Soria, Jean-Charles, primary, Lacroix, Ludovic, primary, André, Fabrice, primary, and Lefebvre, Celine, primary

Published
2023
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7. Supplementary Figure 3 from Improving the Performance of Somatic Mutation Identification by Recovering Circulating Tumor DNA Mutations

Author

Fu, Yu, primary, Jovelet, Cécile, primary, Filleron, Thomas, primary, Pedrero, Marion, primary, Motté, Nelly, primary, Boursin, Yannick, primary, Luo, Yufei, primary, Massard, Christophe, primary, Campone, Mario, primary, Levy, Christelle, primary, Diéras, Véronique, primary, Bachelot, Thomas, primary, Garrabey, Julie, primary, Soria, Jean-Charles, primary, Lacroix, Ludovic, primary, André, Fabrice, primary, and Lefebvre, Celine, primary

Published
2023
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8. Supplementary Methods from Frequent Homologous Recombination Deficiency in High-grade Endometrial Carcinomas

Author

de Jonge, Marthe M., primary, Auguste, Aurélie, primary, van Wijk, Lise M., primary, Schouten, Philip C., primary, Meijers, Matty, primary, ter Haar, Natalja T., primary, Smit, Vincent T.H.B.M., primary, Nout, Remi A., primary, Glaire, Mark A., primary, Church, David N., primary, Vrieling, Harry, primary, Job, Bastien, primary, Boursin, Yannick, primary, de Kroon, Cor D., primary, Rouleau, Etienne, primary, Leary, Alexandra, primary, Vreeswijk, Maaike P.G., primary, and Bosse, Tjalling, primary

Published
2023
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9. Supplementary Figure 1 from Improving the Performance of Somatic Mutation Identification by Recovering Circulating Tumor DNA Mutations

Author

Fu, Yu, primary, Jovelet, Cécile, primary, Filleron, Thomas, primary, Pedrero, Marion, primary, Motté, Nelly, primary, Boursin, Yannick, primary, Luo, Yufei, primary, Massard, Christophe, primary, Campone, Mario, primary, Levy, Christelle, primary, Diéras, Véronique, primary, Bachelot, Thomas, primary, Garrabey, Julie, primary, Soria, Jean-Charles, primary, Lacroix, Ludovic, primary, André, Fabrice, primary, and Lefebvre, Celine, primary

Published
2023
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10. Added Value of Whole-Exome and Transcriptome Sequencing for Clinical Molecular Screenings of Advanced Cancer Patients With Solid Tumors

Author

Koeppel, Florence, Bobard, Alexandre, Lefebvre, Céline, Pedrero, Marion, Deloger, Marc, Boursin, Yannick, Richon, Catherine, Chen-Min-Tao, Romy, Robert, Guillaume, Meurice, Guillaume, Rouleau, Etienne, Michiels, Stefan, Massard, Christophe, Scoazec, Jean-Yves, Solary, Eric, Soria, Jean-Charles, André, Fabrice, and Lacroix, Ludovic

Published
2018
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11. AI-based multi-modal integration of clinical characteristics, lab tests and chest CTs improves COVID-19 outcome prediction of hospitalized patients

Author

Lassau, Nathalie, Ammari, Samy, Chouzenoux, Emilie, Gortais, Hugo, HERENT, Paul, Devilder, Matthieu, Soliman, Samer, Meyrignac, Olivier, Talabard, Marie-Pauline, Lamarque, Jean-Philippe, Dubois, Rémy, Loiseau, Nicolas, Trichelair, Paul, Bendjebbar, Etienne, Garcia, Gabriel, Balleyguier, Corinne, Merad, Mansouria, Stoclin, Annabelle, Jegou, Simon, Griscelli, Franck, Tetelboum, Nicolas, Li, Yingping, Verma, Sagar, Terris, Matthieu, Dardouri, Tasnim, Gupta, Kavya, Neacsu, Ana, Chemouni, Frank, Sefta, Meriem, Jehanno, Paul, Bousaid, Imad, Boursin, Yannick, Planchet, Emmanuel, Azoulay, Mikael, Dachary, Jocelyn, Brulport, Fabien, González, Adrián, Dehaene, Olivier, Schiratti, Jean-Baptiste, Schutte, Kathryn, Pesquet, Jean-Christophe, Talbot, Hugues, Pronier, Elodie, Wainrib, Gilles, Clozel, Thomas, Barlesi, Fabrice, Bellin, Marie-France, Blum, Michael, Unité BioMaps (BIOMAPS), Service Hospitalier Frédéric Joliot (SHFJ), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Département d'imagerie médicale [Gustave Roussy], Institut Gustave Roussy (IGR), OPtimisation Imagerie et Santé (OPIS), Inria Saclay - Ile de France, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre de vision numérique (CVN), Institut National de Recherche en Informatique et en Automatique (Inria)-CentraleSupélec-CentraleSupélec, AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Owkin France, and Inria Saclay Ile de France

Subjects
[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases, [SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

With 15% of severe cases among hospitalized patients​, the SARS-COV-2 pandemic has put tremendous pressure on Intensive Care Units, and made the identification of early predictors of future severity a public health priority. We collected​ ​ clinical and biological data, as well as CT scan images and radiology reports from 1,003 coronavirus-infected patients from two French hospitals. Radiologists' manual CT annotations were also available. We first identified 11 clinical variables and 3 types of radiologist-reported features significantly associated with prognosis. Next, focusing on the CT images, we trained deep learning models to automatically segment the scans and reproduce radiologists' annotations. We also built CT image-based deep learning models that predicted future severity better than models based on the radiologists' scan reports. Finally, we showed that including CT scan features alongside the clinical and biological data yielded more accurate predictions than using clinical and biological data alone. These findings show that CT scans provide insightful early predictors of future severity.

Published
2020

12. AI-based multi-modal integration (ScanCov scores) of clinical characteristics, lab tests and chest CTs improves COVID-19 outcome prediction of hospitalized patients

Author

Lassau, Nathalie, Ammari, Samy, Chouzenoux, Emilie, Gortais, Hugo, Herent, Paul, Devilder, Matthieu, Soliman, Samer, Meyrignac, Olivier, Talabard, Marie-Pauline, Lamarque, Jean-Philippe, Dubois, Rémy, Loiseau, Nicolas, Trichelair, Paul, Bendjebbar, Etienne, Garcia, Gabriel, Balleyguier, Corinne, Merad, Mansouria, Stoclin, Annabelle, Jegou, Simon, Griscelli, Franck, Tetelboum, Nicolas, Li, Yingping, Verma, Sagar, Terris, Matthieu, Dardouri, Tasnim, Gupta, Kavya, Neacsu, Ana, Chemouni, Frank, Sefta, Meriem, Jehanno, Paul, Bousaid, Imad, Boursin, Yannick, Planchet, Emmanuel, Azoulay, Mikael, Dachary, Jocelyn, Brulport, Fabien, González, Adrián, Dehaene, Olivier, Schiratti, Jean-Baptiste, Schutte, Kathryn, Pesquet, Jean-Christophe, Talbot, Hugues, Pronier, Elodie, Wainrib, Gilles, Clozel, Thomas, Barlesi, Fabrice, Bellin, Marie-France, Blum, Michael, Unité BioMaps (BIOMAPS), Service Hospitalier Frédéric Joliot (SHFJ), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Département d'imagerie médicale [Gustave Roussy], Institut Gustave Roussy (IGR), OPtimisation Imagerie et Santé (OPIS), Inria Saclay - Ile de France, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre de vision numérique (CVN), Institut National de Recherche en Informatique et en Automatique (Inria)-CentraleSupélec-Université Paris-Saclay-CentraleSupélec-Université Paris-Saclay, AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Owkin France, Département de soins aigus [Gustave Roussy] (DSA), Inria Saclay Ile de France, LaBoratoire d'Imagerie biOmédicale MultimodAle Paris-Saclay (BIOMAPS), Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases, [SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

The SARS-COV-2 pandemic has put pressure on Intensive Care Units, and made theidentification of early predictors of disease severity a priority. We collected clinical,biological, chest CT scan data, and radiology reports from 1,003 coronavirus-infectedpatients from two French hospitals. Among 58 variables measured at admission, 11clinical and 3 radiological variables were associated with severity. Next, using 506,341chest CT images, we trained and evaluated deep learning models to segment thescans and reproduce radiologists' annotations. We also built CT image-based deeplearning models that predicted severity better than models based on the radiologists'reports. Finally, we showed that adding CT scan information—either throughradiologist lesion quantification or through deep learning—to clinical and biologicaldata, improves prediction of severity. These findings show that CT scans containnovel and unique prognostic information, which we included in a 6-variable ScanCovseverity score.

Published
2020

13. Mutational Profile of Metastatic Breast Cancers: A Retrospective Analysis

Author

Lefebvre, Celine, Bachelot, Thomas, Filleron, Thomas, Pedrero, Marion, Campone, Mario, Soria, Jean-Charles, Massard, Christophe, Lévy, Christelle, Arnedos, Monica, Lacroix-Triki, Magali, Garrabey, Julie, Boursin, Yannick, Deloger, Marc, Fu, Yu, Commo, Frédéric, Scott, Véronique, Lacroix, Ludovic, Dieci, Maria Vittoria, Kamal, Maud, Diéras, Véronique, Gonçalves, Anthony, Ferrerro, Jean-Marc, Romieu, Gilles, Vanlemmens, Laurence, Mouret Reynier, Marie-Ange, Théry, Jean-Christophe, Le Du, Fanny, Guiu, Séverine, Dalenc, Florence, Clapisson, Gilles, Bonnefoi, Hervé, Jimenez, Marta, Le Tourneau, Christophe, and André, Fabrice

Subjects
Gene mutation -- Health aspects, Breast cancer -- Genetic aspects -- Development and progression -- Care and treatment, Biological sciences
Abstract

Background Major advances have been achieved in the characterization of early breast cancer (eBC) genomic profiles. Metastatic breast cancer (mBC) is associated with poor outcomes, yet limited information is available on the genomic profile of this disease. This study aims to decipher mutational profiles of mBC using next-generation sequencing. Methods and Findings Whole-exome sequencing was performed on 216 tumor-blood pairs from mBC patients who underwent a biopsy in the context of the SAFIR01, SAFIR02, SHIVA, or Molecular Screening for Cancer Treatment Optimization (MOSCATO) prospective trials. Mutational profiles from 772 primary breast tumors from The Cancer Genome Atlas (TCGA) were used as a reference for comparing primary and mBC mutational profiles. Twelve genes (TP53, PIK3CA, GATA3, ESR1, MAP3K1, CDH1, AKT1, MAP2K4, RB1, PTEN, CBFB, and CDKN2A) were identified as significantly mutated in mBC (false discovery rate [FDR] < 0.1). Eight genes (ESR1, FSIP2, FRAS1, OSBPL3, EDC4, PALB2, IGFN1, and AGRN) were more frequently mutated in mBC as compared to eBC (FDR < 0.01). ESR1 was identified both as a driver and as a metastatic gene (n = 22, odds ratio = 29, 95% CI [9-155], p = 1.2e-12) and also presented with focal amplification (n = 9) for a total of 31 mBCs with either ESR1 mutation or amplification, including 27 hormone receptor positive (HR+) and HER2 negative (HER2-) mBCs (19%). HR+/HER2- mBC presented a high prevalence of mutations on genes located on the mechanistic target of rapamycin (mTOR) pathway (TSC1 and TSC2) as compared to HR+/HER2- eBC (respectively 6% and 0.7%, p = 0.0004). Other actionable genes were more frequently mutated in HR+ mBC, including ERBB4 (n = 8), NOTCH3 (n = 7), and ALK (n = 7). Analysis of mutational signatures revealed a significant increase in APOBEC-mediated mutagenesis in HR+/HER2- metastatic tumors as compared to primary TCGA samples (p < 2e-16). The main limitations of this study include the absence of bone metastases and the size of the cohort, which might not have allowed the identification of rare mutations and their effect on survival. Conclusions This work reports the results of the analysis of the first large-scale study on mutation profiles of mBC. This study revealed genomic alterations and mutational signatures involved in the resistance to therapies, including actionable mutations., Author(s): Celine Lefebvre 1, Thomas Bachelot 2, Thomas Filleron 3, Marion Pedrero 1, Mario Campone 4, Jean-Charles Soria 1,5,6,7, Christophe Massard 7, Christelle Lévy 8, Monica Arnedos 5, Magali Lacroix-Triki [...]

Published
2016
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15. AI-based multi-modal integration (ScanCov scores) of clinical characteristics, lab tests and chest CTs improves COVID-19 outcome prediction of hospitalized patients

Author

Lassau, Nathalie, primary, Ammari, Samy, additional, Chouzenoux, Emilie, additional, Gortais, Hugo, additional, Herent, Paul, additional, Devilder, Matthieu, additional, Soliman, Samer, additional, Meyrignac, Olivier, additional, Talabard, Marie-Pauline, additional, Lamarque, Jean-Philippe, additional, Dubois, Remy, additional, Loiseau, Nicolas, additional, Trichelair, Paul, additional, Bendjebbar, Etienne, additional, Garcia, Gabriel, additional, Balleyguier, Corinne, additional, Merad, Mansouria, additional, Stoclin, Annabelle, additional, Jegou, Simon, additional, Griscelli, Franck, additional, Tetelboum, Nicolas, additional, Li, Yingping, additional, Verma, Sagar, additional, Terris, Matthieu, additional, Dardouri, Tasnim, additional, Gupta, Kavya, additional, Neacsu, Ana, additional, Chemouni, Frank, additional, Sefta, Meriem, additional, Jehanno, Paul, additional, Bousaid, Imad, additional, Boursin, Yannick, additional, Planchet, Emmanuel, additional, Azoulay, Mikael, additional, Dachary, Jocelyn, additional, Brulport, Fabien, additional, Gonzalez, Adrian, additional, Dehaene, Olivier, additional, Schiratti, Jean-Baptiste, additional, Schutte, Kathryn, additional, Pesquet, Jean-Christophe, additional, Talbot, Hugues, additional, Pronier, Elodie, additional, Wainrib, Gilles, additional, Clozel, Thomas, additional, Barlesi, Fabrice, additional, Bellin, Marie-France, additional, and Blum, Michael G. B., additional

Published
2020
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16. Familial predisposition to TP53/complex karyotype MDS and leukemia in DNA repair-deficient xeroderma pigmentosum

Author

Sarasin, Alain, primary, Quentin, Samuel, additional, Droin, Nathalie, additional, Sahbatou, Mourad, additional, Saada, Véronique, additional, Auger, Nathalie, additional, Boursin, Yannick, additional, Dessen, Philippe, additional, Raimbault, Anna, additional, Asnafi, Vahid, additional, Schmutz, Jean-Luc, additional, Taïeb, Alain, additional, Menck, Carlos F. M., additional, Rosselli, Filippo, additional, La Rochelle, Laurianne Drieu, additional, Robert, Caroline, additional, Sicre de Fontbrune, Flore, additional, Sébert, Marie, additional, Leblanc, Thierry, additional, Kannouche, Patricia, additional, De Botton, Stéphane, additional, Solary, Eric, additional, and Soulier, Jean, additional

Published
2019
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17. Frequent Homologous Recombination Deficiency in High-grade Endometrial Carcinomas

Author

de Jonge, Marthe M., primary, Auguste, Aurélie, additional, van Wijk, Lise M., additional, Schouten, Philip C., additional, Meijers, Matty, additional, ter Haar, Natalja T., additional, Smit, Vincent T.H.B.M., additional, Nout, Remi A., additional, Glaire, Mark A., additional, Church, David N., additional, Vrieling, Harry, additional, Job, Bastien, additional, Boursin, Yannick, additional, de Kroon, Cor D., additional, Rouleau, Etienne, additional, Leary, Alexandra, additional, Vreeswijk, Maaike P.G., additional, and Bosse, Tjalling, additional

Published
2019
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19. Bioconda: A sustainable and comprehensive software distribution for the life sciences

Author

Grüning, Björn, primary, Dale, Ryan, additional, Sjödin, Andreas, additional, Chapman, Brad A., additional, Rowe, Jillian, additional, Tomkins-Tinch, Christopher H., additional, Valieris, Renan, additional, Caprez, Adam, additional, Batut, Bérénice, additional, Haudgaard, Mathias, additional, Cokelaer, Thomas, additional, Beauchamp, Kyle A., additional, Pedersen, Brent S, additional, Hoogstrate, Youri, additional, Bretaudeau, Anthony, additional, Ryan, Devon, additional, Corguillé, Gildas Le, additional, Yusuf, Dilmurat, additional, Luna-Valero, Sebastian, additional, Kirchner, Rory, additional, Brinda, Karel, additional, Wollmann, Thomas, additional, Raden, Martin, additional, Heeringen, Simon J. van, additional, Soranzo, Nicola, additional, Pantano, Lorena, additional, Charlop-Powers, Zachary, additional, Unneberg, Per, additional, Smet, Matthias De, additional, Martin, Marcel, additional, Kuster, Greg Von, additional, Antao, Tiago, additional, Miladi, Milad, additional, Thornton, Kevin, additional, Brueffer, Christian, additional, Beek, Marius van den, additional, Maticzka, Daniel, additional, Blank, Clemens, additional, Will, Sebastian, additional, Gravouil, K´evin, additional, Wolff, Joachim, additional, Holtgrewe, Manuel, additional, Fallmann, Jörg, additional, Piro, Vitor C., additional, Shlyakhter, Ilya, additional, Yousif, Ayman, additional, Mabon, Philip, additional, Zhang, Xiao-Ou, additional, Shen, Wei, additional, Cabral, Jennifer, additional, Thomas, Cristel, additional, Enns, Eric, additional, Brown, Joseph, additional, Boekel, Jorrit, additional, Hollander, Mattias de, additional, Kelleher, Jerome, additional, Turaga, Nitesh, additional, Ruiter, Julian R. de, additional, Bouvier, Dave, additional, Gladman, Simon, additional, Choudhary, Saket, additional, Harding, Nicholas, additional, Eggenhofer, Florian, additional, Kratz, Arne, additional, Fang, Zhuoqing, additional, Kleinkauf, Robert, additional, Timm, Henning, additional, Cock, Peter J. A., additional, Seiler, Enrico, additional, Brislawn, Colin, additional, Nguyen, Hai, additional, Stovner, Endre Bakken, additional, Ewels, Philip, additional, Chambers, Matt, additional, Johnson, James E., additional, Hägglund, Emil, additional, Ye, Simon, additional, Guimera, Roman Valls, additional, Pruesse, Elmar, additional, Dunn, W. Augustine, additional, Parsons, Lance, additional, Patro, Rob, additional, Koppstein, David, additional, Grassi, Elena, additional, Wohlers, Inken, additional, Reynolds, Alex, additional, Cornwell, MacIntosh, additional, Stoler, Nicholas, additional, Blankenberg, Daniel, additional, He, Guowei, additional, Bargull, Marcel, additional, Junge, Alexander, additional, Farouni, Rick, additional, Freeberg, Mallory, additional, Singh, Sourav, additional, Bogema, Daniel R., additional, Cumbo, Fabio, additional, Wang, Liang-Bo, additional, Larson, David E, additional, Workentine, Matthew L., additional, Devisetty, Upendra Kumar, additional, Laurent, Sacha, additional, Roger, Pierrick, additional, Garnier, Xavier, additional, Agren, Rasmus, additional, Khan, Aziz, additional, Eppley, John M, additional, Li, Wei, additional, Stöcker, Bianca Katharina, additional, Rausch, Tobias, additional, Taylor, James, additional, Wright, Patrick R., additional, Taranto, Adam P., additional, Chicco, Davide, additional, Sennblad, Bengt, additional, Baaijens, Jasmijn A., additional, Gopez, Matthew, additional, Abdennur, Nezar, additional, Milne, Iain, additional, Preussner, Jens, additional, Pinello, Luca, additional, Srivastava, Avi, additional, Chande, Aroon T., additional, Kensche, Philip Reiner, additional, Pirola, Yuri, additional, Knudsen, Michael, additional, Bruijn, Ino de, additional, Blin, Kai, additional, Gonnella, Giorgio, additional, Enache, Oana M., additional, Rai, Vivek, additional, Waters, Nicholas R., additional, Hiltemann, Saskia, additional, Bendall, Matthew L., additional, Stahl, Christoph, additional, Miles, Alistair, additional, Boursin, Yannick, additional, Perez-Riverol, Yasset, additional, Schmeier, Sebastian, additional, Clarke, Erik, additional, Arvai, Kevin, additional, Jung, Matthieu, additional, Domenico, Tom´as Di, additional, Seiler, Julien, additional, Rasche, Eric, additional, Kornobis, Etienne, additional, Beisser, Daniela, additional, Rahmann, Sven, additional, Mikheyev, Alexander S, additional, Tran, Camy, additional, Capellades, Jordi, additional, Schröder, Christopher, additional, Salatino, Adrian Emanuel, additional, Dirmeier, Simon, additional, Webster, Timothy H., additional, Moskalenko, Oleksandr, additional, Stephen, Gordon, additional, and Köster, Johannes, additional

Published
2017
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20. Improving the Performance of Somatic Mutation Identification by Recovering Circulating Tumor DNA Mutations

Author

Fu, Yu, primary, Jovelet, Cécile, additional, Filleron, Thomas, additional, Pedrero, Marion, additional, Motté, Nelly, additional, Boursin, Yannick, additional, Luo, Yufei, additional, Massard, Christophe, additional, Campone, Mario, additional, Levy, Christelle, additional, Diéras, Véronique, additional, Bachelot, Thomas, additional, Garrabey, Julie, additional, Soria, Jean-Charles, additional, Lacroix, Ludovic, additional, André, Fabrice, additional, and Lefebvre, Celine, additional

Published
2016
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21. Abstract LB-353: Mutational profile of metastatic breast cancers using whole-exome sequencing: a retrospective analysis of 216 samples from SAFIR01 / 02 / SHIVA / MOSCATO trials

Author

Kamal, Maud, primary, Lefebvre, Celine, additional, Bachelot, Thomas, additional, Filleron, Thomas, additional, Pedrero, Marion, additional, Campone, Mario, additional, Soria, Jean-Charles, additional, Massard, Christophe, additional, Levy, Christelle, additional, Arnedos, Monica, additional, Garrabey, Julie, additional, Boursin, Yannick, additional, Deloger, Marc, additional, Fu, Yu, additional, Commo, Frederic, additional, Scott, Veronique, additional, Lacroix, Ludovic, additional, Martin, Emmanuel, additional, Dieras, Veronique, additional, Goncalves, Anthony, additional, Ferrero, Jean-Marc, additional, Romieu, Gilles, additional, Vanlemmens, Laurence, additional, Mouret-Reynier, Marie-Ange, additional, Thery, Jean-christophe, additional, Kerbrat, Pierre, additional, Guiu, Severine, additional, Dalenc, Florence, additional, Clapisson, Gilles, additional, Bonnefoi, Hervé, additional, Jimenez, Martha, additional, Le Tourneau, Christophe, additional, and Andre, Fabrice, additional

Published
2016
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