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8. EP028 / #48 UTILIZATION OF COMBINATION THERAPY-BASED SCS PROGRAMMING IN CHRONIC PAIN PATIENTS: A REAL-WORLD, OBSERVATIONAL EUROPEAN STUDY

Author

Kallewaard, Jan-Willem, primary, Paz-Solis, Jose, additional, Rigoard, Philippe, additional, Belaid, Hayat, additional, Canos-Verdecho, M. Angeles, additional, Raoul, Sylvie, additional, Llopis-Cataluyd, Jose Emilio, additional, De Negri, Pasquale, additional, Peña, Isaac, additional, Love-Jones, Sarah, additional, Bougeard, Renaud, additional, Thomson, Simon, additional, Chen, Lilly, additional, and Goldberg, Edward, additional

Published
2023
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9. ID: 196541 Utilization of Combination Therapy-Based SCS Programming in Chronic Pain Patients: A Real-World, Observational European Study

Author

Kallewaard, Jan, primary, Paz-Solis, Jose, additional, Rigoard, Philippe, additional, Belaid, Hayat, additional, Canos-Verdecho, M. Angeles, additional, Raoul, Sylvie, additional, Llopis-Cataluyd, Jose, additional, De Negri, Pasquale, additional, Peña, Isaac, additional, Love-Jones, Sarah, additional, Bougeard, Renaud, additional, Maino, Paolo, additional, Thomson, Simon, additional, Chen, Lilly, additional, and Jain, Roshini, additional

Published
2023
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14. Real-World Outcomes Using a Spinal Cord Stimulation Device Capable of Combination Therapy for Chronic Pain: A European, Multicenter Experience

Author

Kallewaard, Jan, primary, Paz-Solis, Jose, additional, De Negri, Pasquale, additional, Canós-Verdecho, Maria, additional, Belaid, Hayat, additional, Thomson, Simon, additional, Abejón, David, additional, Vesper, Jan, additional, Mehta, Vivek, additional, Rigoard, Philippe, additional, Maino, Paolo, additional, Love-Jones, Sarah, additional, Peña, Isaac, additional, Bayerl, Simon, additional, Perruchoud, Christophe, additional, Bougeard, Renaud, additional, Mertz, Cleo, additional, Pei, Yu, additional, and Jain, Roshini, additional

Published
2021
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15. Management of Incidental Durotomy: Results from a Nationwide Survey Conducted by the French Society of Spine Surgery

Author

D'ASTORG, Henri, Szadkowski, Marc, Vieira, Thais Dutra, Dauzac, Cyril, Lonjon, Nicolas, Bougeard, Renaud, Litrico, Stephane, Dupuy, Martin, de Chirurgie du Rachis, Societe Francaise, Hôpital privé Jean-Mermoz [Lyon] (Ramsay-GDS), Service de Neurochirurgie [Montpellier], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-CHU Gui de Chauliac [Montpellier], Mécanismes moléculaires dans les démences neurodégénératives (MMDN), Université de Montpellier (UM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Institut National de la Santé et de la Recherche Médicale (INSERM)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), Clinique du Val d'Ouest, Centre Hospitalier Universitaire de Nice (CHU Nice), and Clinique de l'Union

Subjects
MESH: Neurosurgeons, medicine.medical_treatment, Incidental durotomy, Computer-assisted web interviewing, Nationwide survey, Bed rest, MESH: Thrombin, 0302 clinical medicine, Spine surgery, Primary outcome, Surveys and Questionnaires, Supine Position, Medicine, Fascia, Practice Patterns, Physicians', Intraoperative Complications, Survey, MESH: Muscle, Skeletal, Thrombin, MESH: Tissue Adhesives, 3. Good health, Management, Drug Combinations, Adipose Tissue, Current management, 030220 oncology & carcinogenesis, MESH: Supine Position, MESH: Intraoperative Complications, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], France, Spinal surgery, MESH: Spine, MESH: Adipose Tissue, medicine.medical_specialty, MESH: Bed Rest, Fibrin Tissue Adhesive, [SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery, MESH: Dura Mater, MESH: Suture Techniques, 03 medical and health sciences, MESH: Orthopedic Surgeons, Humans, MESH: Surveys and Questionnaires, Muscle, Skeletal, MESH: Drug Combinations, MESH: Fascia, MESH: Fibrin Tissue Adhesive, MESH: Humans, business.industry, Questionnaire, General surgery, Suture Techniques, Fibrinogen, Orthopedic Surgeons, Spine, MESH: France, Neurosurgeons, MESH: Fibrinogen, MESH: Practice Patterns, Physicians', Tissue Adhesives, Surgery, Dura Mater, Neurology (clinical), business, Bed Rest, 030217 neurology & neurosurgery, Continuous suture
Abstract

International audience; Objective: To obtain real-life data on the most common practices used for management of incidental durotomy (ID) in France.Methods: Data were collected from spinal surgeons using a practice-based online questionnaire. The survey comprised 31 questions on the current management of ID in France. The primary outcome was the identification of areas of consensus and uncertainty on ID follow-up.Results: A total of 217 surgeons (mainly orthopaedic surgeons and neurosurgeons) completed the questionnaire and were included in the analysis. There was a consensus on ID repair with 94.5% of the surgeons considering that an ID should always be repaired, if repairable, and 97.2% performing a repair if an ID occurred. The most popular techniques were simple suture or locked continuous suture (48.3% vs. 57.8% of surgeons). Nonrepairable IDs were more likely to be treated with surgical sealants than with an endogenous graft (84.9% vs. 75.5%). Almost two thirds of surgeons (71.6%) who adapted their standard postoperative protocol after an ID recommended bed rest in the supine position. Among these, 48.8% recommended 24 hours of bed rest, while 53.5% recommended 48 hours of bed rest. The surgeons considered that the main risk factors for ID were revision surgery (98.6%), patient's age (46.8%), surgeon's exhaustion (46.3%), and patient's weight (21.3%).Conclusions: This nationwide survey reflects the lack of a standardized management protocol for ID. Practices among surgeons remain very heterogeneous. Further consensus studies are required to develop a standard management protocol for ID.

Published
2020
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18. Spinal cord stimulation for chronic refractory pain: Long-term effectiveness and safety data from a multicentre registry.

Author

Brinzeu, Andrei, Cuny, Emmanuel, Fontaine, Denys, Mertens, Patrick, Luyet, Pierre‐Philippe, Van den Abeele, Carine, Djian, Marie‐Christine, Le Borgne, Jean‐Marie, Palfi, Stephane, Sol, Jean‐Christophe, Fowo, Sylvain, Desenclos, Christine, Gadan, Roberto, Nizar, Suleiman, Simon, Emile, Barat, Jean‐Luc, Blond, Serge, Buisset, Nadia, Bougeard, Renaud, and Borius, Pierre‐Yves

Abstract

Background: Spinal cord stimulation (SCS) is an established therapy for refractory neuropathic pain. To ascertain the balance between treatment benefits and risks, the French National Authority for Health requested a post-market registry for real-world evaluation of the long-term effectiveness and safety of the therapy.Methods: A total of 402 patients undergoing implantation with a Medtronic SCS device as either a primo-implant (n = 264) or replacement implant (n = 138) were enrolled across 28 representative sites in France. Outcome measures at 2 years included pain intensity, satisfaction with treatment, improvement of pain relief and daily life activity, willingness to undergo the treatment again and use of pain treatments. A patient was considered a responder if, compared to baseline, predominant pain reduction was ≥50%.Results: At the 2-year follow-up visit, predominant pain intensity for primo-implant patients had decreased from baseline (p < 0.001), with responder rates of 55%, 36% and 67% for the lower limbs, back and upper limbs, respectively. Most patients acknowledged an improvement in pain relief (89%) and daily life activity (82%) were satisfied with treatment (91%) and willing to undergo the treatment again (93%). A significant decrease (p < 0.01) in the proportion of patients receiving pain treatment was observed for all drug and non-drug treatments. Reported adverse events were in line with the literature. Pain intensity at 2 years was comparable for patients in the replacement group, supporting the long-term stability and effectiveness of SCS.Conclusion: Real-world evaluation of the use of spinal cord stimulation under the recommendations of the French Health Authority shows that two years after the first implantation of an SCS device close to 60% of the patients retain a significant pain reduction and 74% show improvement in pain scores [of at least 30%] with significant decreases in drug and non-drug pain treatments.Significance: This observational, prospective study in a real-life setting followed a large cohort of patients suffering from chronic pain and implanted with SCS devices in France. The study assessed the long-term effectiveness and safety of SCS therapy in a representative sample of implanting sites in France. [ABSTRACT FROM AUTHOR]

Published
2019
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