7 results on '"Bottiger, Y."'
Search Results
2. The European Association for Clinical Pharmacology and Therapeutics-25 years' young and going strong
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Coleman, J.J., Samer, C., Zeitlinger, M., Agtmael, M. van, Rongen, G.A.P.J.M., Marquet, P., Simon, T., Singer, D., Manolopoulos, V.G., Bottiger, Y., Coleman, J.J., Samer, C., Zeitlinger, M., Agtmael, M. van, Rongen, G.A.P.J.M., Marquet, P., Simon, T., Singer, D., Manolopoulos, V.G., and Bottiger, Y.
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Contains fulltext : 205530.pdf (publisher's version ) (Open Access), Clinical pharmacology as a scientific discipline and medical specialty was unarguably born in the twentieth century. Whilst pharmacology-the science behind the treatment of disease-had been in evolution since at least medieval times, the clinical discipline of pharmacology has had a more recent genesis and rather insidious evolution. During the 1900s, there were some clear father (parent) figures of clinical pharmacology in Europe that emerged and were responsible for the development of the specialty in this continent. This was a time when there were parallel developments in geographically dispersed academic departments (around the globe), during an age of excitement in drug discovery and clinical application of new therapeutic agents. It was the meeting of minds of some of these progenitors of the specialty that led to the development of the European Association for Clinical Pharmacology and Therapeutics (EACPT) 25 years ago arising from a working party supported by the World Health Organization in Europe. The EACPT now includes all major national organizations for clinical pharmacology in Europe, representing over 4000 individual professionals interested in clinical pharmacology and therapeutics. The EACPT has a major interest in promoting the safe use of medicines across Europe and internationally and has supported these aims since 1995, through biennial international scientific congresses and summer schools with delegates and presenters from around the world as well as various working group activities. In this article, the current executive committee members of EACPT recall this history, describe the evolution of the association over the last quarter of a century, and provide an update on the activities and ambitions of the association today.
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- 2019
3. Trimethoprim-sulphamethoxazole does not affect the pharmacokinetics of sirolimus in renal transplant recipients.
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Bottiger, Y, Brattström, C, Bäckman, L, Claesson, Kerstin, Burke, JT, Bottiger, Y, Brattström, C, Bäckman, L, Claesson, Kerstin, and Burke, JT
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- 2005
4. Pharmacokinetic interaction between single oral doses of ditiazem and sirolimus in healthy volunteers*1
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BOTTIGER, Y, primary
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- 2001
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5. European List of Essential Medicines for Medical Education: A protocol for a modified Delphi study
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Paraskevi Papaioannidou, Erik Donker, Emilio J. Sanz, Ylva Böttiger, Fabrizio De Ponti, Michiel A. van Agtmael, M.C. Richir, Rahul Pandit, David J. Brinkman, Jelle Tichelaar, Cornelis Kramers, João Costa, Robert Likić, Milo Gatti, Thierry Christiaens, Sarah Garner, VU University medical center, Anesthesiology, Internal medicine, AGEM - Endocrinology, metabolism and nutrition, Other Research, Donker E., Brinkman D., Richir M., Papaioannidou P., Likic R., Sanz E.J., Christiaens T., Costa J., De Ponti F., Gatti M., Bottiger Y., Kramers C., Garner S., Pandit R., Van Agtmael M., Tichelaar J., Graduate School, and Amsterdam Gastroenterology Endocrinology Metabolism
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training) ,Delphi Technique ,Social and Clinical Pharmacy ,Modified delphi ,030226 pharmacology & pharmacy ,Essential medicines ,law.invention ,0302 clinical medicine ,law ,therapeutics ,Medicine ,University medical ,030212 general & internal medicine ,Netherlands ,computer.programming_language ,training ,Clinical pharmacology ,Education, Medical ,General Medicine ,education & ,Education, Medical, Undergraduate ,education & training (see medical education & training) ,medical education & training ,Europe ,Clinical Competence ,Curriculum ,Human ,education ,training (see medical education & ,Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18] ,03 medical and health sciences ,All institutes and research themes of the Radboud University Medical Center ,Netherland ,medical education & ,Humans ,Protocol (science) ,Medical education ,business.industry ,Samhällsfarmaci och klinisk farmaci ,Medical Education and Training ,therapeutic ,Medical training ,business ,computer ,Delphi ,Medical ethics - Abstract
IntroductionJunior doctors are responsible for a substantial number of prescribing errors, and final-year medical students lack sufficient prescribing knowledge and skills just before they graduate. Various national and international projects have been initiated to reform the teaching of clinical pharmacology and therapeutics (CP&T) during undergraduate medical training. However, there is as yet no list of commonly prescribed and available medicines that European doctors should be able to independently prescribe safely and effectively without direct supervision. Such a list could form the basis for a European Prescribing Exam and would harmonise European CP&T education. Therefore, the aim of this study is to reach consensus on a list of widely prescribed medicines, available in most European countries, that European junior doctors should be able to independently prescribe safely and effectively without direct supervision: the European List of Essential Medicines for Medical Education.Methods and analysisThis modified Delphi study will recruit European CP&T teachers (expert group). Two Delphi rounds will be carried out to enable a list to be drawn up of medicines that are available in ≥80% of European countries, which are considered standard prescribing practice, and which junior doctors should be able to prescribe safely and effectively without supervision.Ethics and disseminationThe study has been approved by the Medical Ethics Review Committee of VU University Medical Center (no. 2020.335) and by the Ethical Review Board of the Netherlands Association for Medical Education (approved project no. NVMO‐ERB 2020.4.8). The European List of Essential Medicines for Medical Education will be presented at national and international conferences and will be submitted to international peer-reviewed journals. It will also be used to develop and implement the European Prescribing Exam.
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- 2021
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6. EurOP2E – the European open platform for prescribing education, a consensus study among clinical pharmacology and therapeutics teachers
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Bakkum, Michiel J., Richir, Milan C., Papaioannidou, Paraskevi, Likic, Robert, Sanz, Emilio J., Christiaens, Thierry, Costa, João N., Maciulaitis, Romaldas, Dima, Lorena, Coleman, Jamie, Tichelaar, Jelle, van Agtmael, Michiel A., Atanasova, Ivanka, Ganeva, Maria, Gatchev, Emil, Kostadinova, I.I., Matanovic, S. Mimica, Vitezic, D., Wozniak, Greta, Kmonickova, E., Urbanek, Karel, Damkier, P., Huupponen, R. K., Auffret, Marine, Bejan-Angoulvant, T., Chouchana, Laurent, Cracowski, Jean-Luc, Drici, M. D., Faillie, J. L., Geniaux, Hélène, Molimard, M., Orlikowski, D., Palin, Karine, Pers, Y-M, Picard, Nicolas, Simon, N., Toussirot, E., Boger, R. H., Cascorbi, I., Mueller, S. C., Regenthal, R., Schwab, M., Schwaninger, M. S., Thuermann, P. A., Wojnowski, L., Kouvelas, D., Riba, P., Kerins, David M., Williams, David J., Cosentino, M., De Ponti, Fabrizio, Filippelli, Amelia, Leone, R., Locatelli, Vittorio, Jansone, Baiba, Gulbinovic, Romaldas, Mifsud, Janet, Braszko, Jan J., Kocic, I., Breitenfeld, Luiza, Castelo-Branco, M., Conea, Simona, Magyar, Ioan, Bevc, S., Krzan, Mojca, Bernal, M. L., Capellà, D., Carcas, A., De Abajo, F. J., Lopez-Rico, M., Lucena, M. I., Pontes, C., Sanz, E. J., Böttiger, Y., Le Grevès, Madeleine, de Waard-Siebinga, I., Janssen, Ben J. A., Knol, Wilma, Pandit, Rahul, van Rosse, F., Dent, G., Ferro, Albert, Hitchings, A. W., Kapil, V., Linton, K. D., Loke, Y. K., Okorie, Michael, Plumb, Richard David, Pontefract, Sarah, Ranmuthu, S., Sampson, A. P., Thanacoody, H. K. R., Whitfield, Jonathan P., Wilson, Kurt, Bakkum M.J., Richir M.C., Papaioannidou P., Likic R., Sanz E.J., Christiaens T., Costa J.N., Maciulaitis R., Dima L., Coleman J., Tichelaar J., van Agtmael M.A., Atanasova I., Ganeva M., Gatchev E., Kostadinova I.I., Matanovic S.M., Vitezic D., Wozniak G., Kmonickova E., Urbanek K., Damkier P., Huupponen R.K., Auffret M., Bejan-Angoulvant T., Chouchana L., Cracowski J.-L., Drici M.D., Faillie J.L., Geniaux H., Molimard M., Orlikowski D., Palin K., Pers Y.-M., Picard N., Simon N., Toussirot E., Boger R.H., Cascorbi I., Mueller S.C., Regenthal R., Schwab M., Schwaninger M.S., Thuermann P.A., Wojnowski L., Kouvelas D., Riba P., Kerins D.M., Williams D.J., Cosentino M., De Ponti F., Filippelli A., Leone R., Locatelli V., Jansone B., Gulbinovic R., Mifsud J., Braszko J.J., Kocic I., Breitenfeld L., Castelo-Branco M., Conea S., Magyar I., Bevc S., Krzan M., Bernal M.L., Capella D., Carcas A., De Abajo F.J., Lopez-Rico M., Lucena M.I., Pontes C., Bottiger Y., Le Greves M., de Waard-Siebinga I., Janssen B.J.A., Knol W., Pandit R., van Rosse F., Dent G., Ferro A., Hitchings A.W., Kapil V., Linton K.D., Loke Y.K., Okorie M., Plumb R.D., Pontefract S., Ranmuthu S., Sampson A.P., Thanacoody H.K.R., Whitfield J.P., Wilson K., Internal medicine, Other Research, CCA - Cancer Treatment and quality of life, Bakkum, M, Richir, M, Papaioannidou, P, Likic, R, Sanz, E, Christiaens, T, Costa, J, Mačiulaitis, R, Dima, L, Coleman, J, Tichelaar, J, van Agtmael, M, and Locatelli, V
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Medical education ,Open platform ,Quality management ,Pharmacoepidemiology and Prescription ,Teaching Materials ,media_common.quotation_subject ,Language barrier ,030226 pharmacology & pharmacy ,Open educational resources ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,law ,Political science ,Copyright ,ComputingMilieux_COMPUTERSANDEDUCATION ,Humans ,Pharmacology (medical) ,Quality (business) ,Cooperative Behavior ,Adaptation (computer science) ,Schools, Medical ,media_common ,Pharmacology ,Clinical pharmacology ,05 social sciences ,Open educational resource ,050301 education ,General Medicine ,Quality Improvement ,Clinical pharmacology and therapeutic ,Europe ,Digital education ,Educational resources ,Pharmacology, Clinical ,clinical pharmacology and therapeutics ,digital education ,medical education ,open educational resources ,0503 education ,Clinical pharmacology and therapeutics ,Human - Abstract
Purpose Sharing and developing digital educational resources and open educational resources has been proposed as a way to harmonize and improve clinical pharmacology and therapeutics (CPT) education in European medical schools. Previous research, however, has shown that there are barriers to the adoption and implementation of open educational resources. The aim of this study was to determine perceived opportunities and barriers to the use and creation of open educational resources among European CPT teachers and possible solutions for these barriers. Methods CPT teachers of British and EU medical schools completed an online survey. Opportunities and challenges were identified by thematic analyses and subsequently discussed in an international consensus meeting. Results Data from 99 CPT teachers from 95 medical schools were analysed. Thirty teachers (30.3%) shared or collaboratively produced digital educational resources. All teachers foresaw opportunities in the more active use of open educational resources, including improving the quality of their teaching. The challenges reported were language barriers, local differences, lack of time, technological issues, difficulties with quality management, and copyright restrictions. Practical solutions for these challenges were discussed and include a peer review system, clear indexing, and use of copyright licenses that permit adaptation of resources. Conclusion Key challenges to making greater use of CPT open educational resources are a limited applicability of such resources due to language and local differences and quality concerns. These challenges may be resolved by relatively simple measures, such as allowing adaptation and translation of resources and a peer review system.
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- 2021
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7. Harmonizing and improving European education in prescribing: An overview of digital educational resources used in clinical pharmacology and therapeutics
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Bakkum, Michiel J., Tichelaar, Jelle, Papaioannidou, Paraskevi, Likic, Robert, Sanz Alvarez, Emilio J., Christiaens, Thierry, Costa, João N., Mačiulaitis, Romaldas, Dima, Lorena, Coleman, Jamie, Richir, Milan C., Agtmael, Michiel A., Atanasova, Ivanka, Ganeva, Maria, Gatchev, Emil, Kostadinova, I. I., Mimica Matanovic, S., Vitezic, D, Greta, Wozniak, Kmonickova, E., Karel, Urbanek, Damkier, P., Huupponen, R. K., Auffret, Marine, Bejan‐ Angoulvant, T., Laurent, Chouchana, Jean‐Luc, Cracowski, Drici, M. D., Faillie, J. L., Hélène, Geniaux, Molimard, M., Orlikowski, D., Palin, Karine, Pers, Y.‐M., Picard, Nicolas, Simon, N., Toussirot, E., Boger, R. H., Cascorbi, I., Mueller, S. C., Regenthal, R., Schwab, M., Schwaninger, M. S., Thuermann, P. A., Wojnowski, L., Kouvelas, D., Riba, P., Kerins, David M., Williams, David J., Cosentino, M., De Ponti, Fabrizio, Filippelli, Amelia, Leone, R., Locatelli, Vittorio, Jansone, Baiba, Gulbinovic, Romaldas, Mifsud, Janet, Braszko Jan, J., Kocic, I., Luiza, Breitenfeld, Castelo‐Branco, M., Simona, Conea, Ioan, Magyar, Bevc, S., Mojca, Krzan, Bernal, M. L., Capellà, D., Carcas, A., De Abajo, F. J., Lopez‐Rico, M., Lucena, M. I., Pontes, C., Sanz, E. J., Böttiger, Y., Le Grevès, Madeleine, Waard‐Siebinga, I., Janssen Ben, J. A., Wilma, Knol, Rahul, Pandit, Rosse, F., Dent, G., Albert, Ferro, Hitchings, A. W., Kapil, V., Linton, K. D., Loke, Y. K., Michael, Okorie, David, Plumb Richard, Pontefract, Sarah, Ranmuthu, S., Sampson, A. P., Thanacoody, H. K. R., Whitfield Jonathan, P., Wilson, Kurt, for the Education Working Group of the European Association for Clinical Pharmacology and Therapeutics (EACPT) and its affiliated Network of Teachers in Pharmacotherapy (NOTIP), Bakkum, M, Tichelaar, J, Papaioannidou, P, Likic, R, Sanz Alvarez, E, Christiaens, T, Costa, J, Mačiulaitis, R, Dima, L, Coleman, J, Richir, M, van Agtmael, M, Locatelli, V, Internal medicine, Other Research, Bakkum M.J., Tichelaar J., Papaioannidou P., Likic R., Sanz Alvarez E.J., Christiaens T., Costa J.N., Maciulaitis R., Dima L., Coleman J., Richir M.C., van Agtmael M.A., Atanasova I., Ganeva M., Gatchev E., Kostadinova I.I., Mimica Matanovic S., Vitezic D., Greta W., Kmonickova E., Karel U., Damkier P., Huupponen R.K., Auffret M., Bejan-Angoulvant T., Laurent C., Jean-Luc C., Drici M.D., Faillie J.L., Helene G., Molimard M., Orlikowski D., Palin K., Pers Y.-M., Picard N., Simon N., Toussirot E., Boger R.H., Cascorbi I., Mueller S.C., Regenthal R., Schwab M., Schwaninger M.S., Thuermann P.A., Wojnowski L., Kouvelas D., Riba P., Kerins D.M., Williams D.J., Cosentino M., De Ponti F., Filippelli A., Leone R., Locatelli V., Jansone B., Gulbinovic R., Mifsud J., Braszko Jan J., Kocic I., Luiza B., Castelo-Branco M., Simona C., Ioan M., Bevc S., Mojca K., Bernal M.L., Capella D., Carcas A., De Abajo F.J., Lopez-Rico M., Lucena M.I., Pontes C., Bottiger Y., Le Greves M., de Waard-Siebinga I., Janssen Ben J.A., Wilma K., Rahul P., van Rosse F., Dent G., Albert F., Hitchings A.W., Kapil V., Linton K.D., Loke Y.K., Michael O., David P.R., Pontefract S., Ranmuthu S., Sampson A.P., Thanacoody H.K.R., Whitfield Jonathan P., and Wilson K.
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Computer-Assisted Instruction ,Harmonization ,030226 pharmacology & pharmacy ,law.invention ,open educational resource ,03 medical and health sciences ,0302 clinical medicine ,Medicaments -- Prescripció ,law ,clinical pharmacology and therapeutic ,Humans ,Learning ,Pharmacology (medical) ,Narrative ,030212 general & internal medicine ,Curriculum ,Schools, Medical ,Cross-Sectional Studie ,Pharmacology ,education ,Medical education ,Prescribing ,clinical pharmacology and therapeutics ,digital ,open educational resources ,Clinical pharmacology ,Drugs -- Prescribing ,Principal (computer security) ,Open educational resources ,Variety (cybernetics) ,Cross-Sectional Studies ,Pharmacology, Clinical ,Psychology ,Human - Abstract
CONTRIBUTORS IN THE NETWORK OF TEACHERS IN PHARMACOTHERAPY (NOTIP) (ALPHABETIZED BY COUNTRY): Atanasova, Ivanka (Sofia University St. Kliment Ohridski, Sofia, Bulgaria); Ganeva, Maria (Trakia University, Stara Zagora, Bulgaria); Gatchev, Emil (Medical University of Sofia, Sofia, Bulgaria); Kostadinova, II (Medical University Plovdiv, Plovdiv, Bulgaria); Mimica Matanovic, S (University of Osijek, Osijek, Croatia); Vitezic, D (University of Rijeka Medical School, Rijeka, Croatia); Wozniak, Greta (University of Cyprus, Nicosia, Cyprus); Kmonickova, E (Charles University, Pilsen, Czech Republic); Urbanek, Karel (Palacky University, Olomouc, Czech Republic); Damkier, P (University of Southern Denmark, Odense, Denmark); Huupponen, RK (University of Turku, Turku, Finland); Auffret, Marine (Hospices civils de Lyon, Lyon, France); Bejan-Angoulvant, T (Université de Tours, Tours, France); Chouchana, Laurent (Hospital Cochin, Paris, France); Cracowski, Jean-Luc (University Grenoble Alpes, La Tronche, France); Drici, MD (University of Nice Côte d'Azur, Nice, France); Faillie, JL (CHU Montpellier, Montpellier, France); Geniaux, Hélène (CHU de Limoges, Limoges, France); Molimard, M (Université de Bordeaux, Bordeaux, France); Orlikowski, D (Versailles Saint-Quentin-en-Yvelines University, Versailles, France); Palin, Karine (University of Bordeaux, Bordeaux, France); Pers, Y-M (CHU Montpellier, Montpellier, France); Picard, Nicolas (CHU de Limoges, Limoges, France); Simon, N (Aix-Marseille University, Marseille, France); Toussirot, E (CHU de Besancon, Besancon, France); Boger, RH (University Medical Center Hamburg-Eppendorf, Hamburg, Germany); Cascorbi, I (University of Kiel, Kiel, Germany); Mueller, SC (University Medicine Rostock, Rostock, Germany); Regenthal, R (University of Leipzig, Leipzig, Germany); Schwab, M (Eberhard Karl University of Tübingen, Tübingen, Germany); Schwaninger, MS (University of Luebeck, Luebeck, Germany); Thuermann, PA (University Witten/Herdecke, Witten, Germany); Wojnowski, L (University Medical Center Mainz, Mainz, Germany); Kouvelas, D (Aristotle University of Thessaloniki, Thessaloniki, Greece); Riba, P (Semmelweis University, Budapest, Hungary); Kerins, David M (University College, Cork, Ireland); Williams, David J (Royal College of Surgeons in Ireland, Dublin, Ireland); Cosentino, M (University of Insubria, Varese, Italy); De Ponti, Fabrizio (University of Bologna, Bologna, Italy); Filippelli, Amelia (University of Salerno, Baronissi, Italy); Leone, R (University of Verona, Verona, Italy); Locatelli, Vittorio (University of Milano - Bicocca, Monza, Italy); Jansone, Baiba (University of Latvia, Riga, Latvia); Gulbinovic, Romaldas (Vilnius University, Vilnius, Lithuania); Mifsud, Janet (University of Malta, Msida, Malta); Braszko, Jan J (Medical University of Bialystok, Bialystok, Poland); kocic, I (Medical University of Gdansk, Gdansk, Poland); Breitenfeld, Luiza (Beira Interior University, Covilh~a, Portugal); Castelo-Branco, M (University of Beira Interior, Covilh~a, Portugal); Conea, Simona (“Vasile Goldis” Western University of Arad, Arad, Romania); Magyar, Ioan (University of Oradea, Oradea, Romania); Bevc, S (University of Maribor, Maribor, Slovenia); Krzan, Mojca (University of Ljubljana, Ljubljana, Slovenia); Bernal, ML (University of Zaragoza, Zaragoza, Spain); Capellà, D (University of Girona, Girona, Spain); Carcas, A (Universidad Autónoma de Madrid, University of Maribor, Spain); De Abajo, FJ (University of Alcalá, Alcalá de Henares, Spain); Lopez-Rico, M (University of Salamanca, Salamanca, Spain); Lucena, MI (University of Malaga, Malaga, Spain); Pontes, C (Universitat Autonoma de Barcelona, Sabadell, Spain); Sanz, EJ (Universidad de La Laguna, La Laguna, Spain); Böttiger, Y (Linköping University, Linköping, Sweden); Le Grevès, Madeleine (Uppsala University, Uppsala, Sweden); de Waard-Siebinga, I (University Medical Center Groningen, Groningen, The Netherlands); Janssen, Ben JA (Maastricht University, Maastricht, The Netherlands); Knol, Wilma (University Medical Center Utrecht, Utrecht, The Netherlands); Pandit, Rahul (University Medical Center Utrecht, Utrecht, The Netherlands); van Rosse, F (Erasmus Medical Center, Rotterdam, The Netherlands); Dent, G (Keele University, Keele, United Kingdom); Ferro, Albert (King's College London, London, United Kingdom); Hitchings, AW (St George's, University of London, London, United Kingdom); Kapil, V (Queen Mary University London, London, United Kingdom); Linton, KD (University of Sheffield, Sheffield, United Kingdom); Loke, YK (University of East Anglia, Norwich, United Kingdom); Okorie, Michael (Brighton and Sussex Medical School, Brighton, United Kingdom); Plumb, Richard David (Queen's University Belfast, Belfast, United Kingdom); Pontefract, Sarah (University of Birmingham, Birmingham, United Kingdom); Ranmuthu, S (Queen Mary University London, London, United Kingdom); Sampson, AP (University of Southampton, Southampton, United Kingdom); Thanacoody, HKR (Newcastle University, Newcastle upon Tyne, United Kingdom); Whitfield, Jonathan P (University of Aberdeen, Aberdeen, United Kingdom); Wilson, Kurt (University of Manchester, Manchester, United Kingdom) Improvement and harmonization of European clinical pharmacology and therapeutics (CPT) education is urgently required. Because digital educational resources can be easily shared, adapted to local situations and re‐used widely across a variety of educational systems, they may be ideally suited for this purpose Methods With a cross‐sectional survey among principal CPT teachers in 279 out of 304 European medical schools, an overview and classification of digital resources was compiled. Results Teachers from 95 (34%) medical schools in 26 of 28 EU countries responded, 66 (70%) of whom used digital educational resources in their CPT curriculum. A total of 89 of such resources were described in detail, including e‐learning (24%), simulators to teach pharmacokinetics and/or pharmacodynamics (10%), virtual patients (8%), and serious games (5%). Together, these resources covered 235 knowledge‐based learning objectives, 88 skills, and 13 attitudes. Only one third (27) of the resources were in‐part or totally free and only two were licensed open educational resources (free to use, distribute and adapt). A narrative overview of the largest, free and most novel resources is given. Conclusion Digital educational resources, ranging from e‐learning to virtual patients and games, are widely used for CPT education in EU medical schools. Learning objectives are based largely on knowledge rather than skills or attitudes. This may be improved by including more real‐life clinical case scenarios. Moreover, the majority of resources are neither free nor open. Therefore, with a view to harmonizing international CPT education, more needs to be learned about why CPT teachers are not currently sharing their educational materials.
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- 2020
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