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204 results on '"Boso, Daniela"'

1. An integrated DEM-FEM approach to study breakage in packing of glass cartridges on a conveyor belt

Author

Boso, Daniela, Braga, Tommaso, Ravasini, Simone, Skrbic, Tatjana, Puglisi, Andrea, Pinato, Odra, Chillon, Alberto, Frare, Maria Chiara, and Giacometti, Achille

Subjects
Condensed Matter - Soft Condensed Matter, Condensed Matter - Statistical Mechanics
Abstract

The use of glass for pharmaceutical new applications such as high-technology drugs, requires the strictest container inertness. A common theme of paramount importance in glass container integrity preservation is the detailed mechanism driving the sudden failure due the crack propagation. Using a combination of Discrete Element Method (DEM) and Finite Element Method (FEM), a stress map for glass cartridges packed into an accumulation table and transported by a conveyor belt at a fixed velocity is obtained under realistic conditions. The DEM calculation provides a full description of the dynamics of the cartridges, as approximated by an equivalent sphere, as well as the statistics of the multiple collisions. The FEM calculation exploits this input to provide the maximum principal stress of different pairs as a function of time. Our analysis shows that, during their transportation on the conveyor belt, the cartridges are subject to several shocks of varying intensities. Under these conditions, a crack may originate inside the cartridge in the area of maximal tensile stress, and propagate outward. Estimated stresses are found in good agreement with real systems., Comment: 20 pages, 13 Figures, in press

Published
2020

23. Thermo-electro-mechanical coupling in beam-to-beam contact

Author

Boso, Daniela P., Schrefler, Bernhard A., Litewka, Przemyslaw, Wriggers, Peter, Motasoares, C. A., editor, Martins, J. A. C., editor, Rodrigues, H. C., editor, Ambrósio, Jorge A. C., editor, Pina, C. A. B., editor, Motasoares, C. M., editor, Pereira, E. B. R., editor, and Folgado, J., editor

Published
2006
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27. A biphasic model for avascular tumor growth and drug response

Author

Mascheroni, Pietro, Boso, Daniela, Stigliano, Cinzia, Carfagna, Melania, Preziosi, Luigi, Decuzzi, Paolo, and A. Schrefler, Bernhard

Subjects
Drug Response, Mathematical Modeling, Mechanical Compression of Spheroids, Tumor Spheroids, Growth Inhibition, Cancer Growth, Mathematical Modeling, Cancer Growth, Tumor Spheroids, Mechanical Compression of Spheroids, Growth Inhibition, Drug Response
Published
2016

29. A porous media approach for plantar tissue during gait

Author

Boso, Daniela, Sciumè, G., Pizzocaro, M., and Schrefler, B. A.

Subjects
Thermodynamically constrained averaging theory, Porous medium, Thermodynamically constrained averaging theory, Porous medium, Plantar tissue mechanics, Plantar tissue mechanics
Published
2015

31. Tumor growth modeling in the framework of porous media mechanics

Author

Mascheroni, P., Santagiuliana, R., Sciumè, G., Ferrari, M., Decuzzi, P., Boso, Daniela, and Schrefler, B. A.

Subjects
tumor growth, Finite Element Method, melanoma, Porous media mechanics, Porous media mechanics, multiphase systems, Finite Element Method, tumor growth, melanoma, multiphase systems
Published
2015

37. A two-phase model of plantar tissue: a step toward prediction of diabetic foot ulceration

Author

Sciumè, G., Boso, Daniela, Gray, W. G., Cobelli, Claudio, and Schrefler, Bernhard

Subjects
Models, Anatomic, Weight-Bearing, TCAT, Foot, Effective Stress Principle, multiphase materials, Porous media, Humans, Thermodynamics, Models, Biological, Algorithms, Diabetic Foot
Abstract

A new computational model, based on the thermodynamically constrained averaging theory, has been recently proposed to predict tumor initiation and proliferation. A similar mathematical approach is proposed here as an aid in diabetic ulcer prevention. The common aspects at the continuum level are the macroscopic balance equations governing the flow of the fluid phase, diffusion of chemical species, tissue mechanics, and some of the constitutive equations. The soft plantar tissue is modeled as a two-phase system: a solid phase consisting of the tissue cells and their extracellular matrix, and a fluid one (interstitial fluid and dissolved chemical species). The solid phase may become necrotic depending on the stress level and on the oxygen availability in the tissue. Actually, in diabetic patients, peripheral vascular disease impacts tissue necrosis; this is considered in the model via the introduction of an effective diffusion coefficient that governs transport of nutrients within the microvasculature. The governing equations of the mathematical model are discretized in space by the finite element method and in time domain using the θ-Wilson Method. While the full mathematical model is developed in this paper, the example is limited to the simulation of several gait cycles of a healthy foot.

Published
2013

46. Inverse Problem: a Soft Solution

Author

Boso, Daniela and Lefik, M.

Subjects
Convection problems, Self Consistent Homogenisation, Parameter identification, inverse problems, Soft methods, Artificial Neural Networks
Published
2012

48. Multiscale Numerical Modeling of Composite Material: a Combined FE-ANN Approach

Author

Boso, Daniela, Lefik, Marek, and Schrefler, Bernhard A.

Subjects
Artificial Neural Network, Artificial Neural Networks, Virtual Testing, Numerical homogenization, Stress – Strain Recovery, multiscale analysis, Non linear composites, Computational Theory and Mathematics, Applied Mathematics, Multiscale Analysis, Non Linear Composites, Stress - Strain Recovery
Published
2012

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