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32 results on '"Bortone, Agustín"'

4. Maximal Pre-Excitation Based Algorithm for Localization of Manifest Accessory Pathways in Adults

Author

Pambrun, Thomas, El Bouazzaoui, Rim, Combes, Nicolas, Combes, Stéphane, Sousa, Pedro, Le Bloa, Mathieu, Massoullié, Grégoire, Cheniti, Ghassen, Martin, Ruairidh, Pillois, Xavier, Duchateau, Josselin, Sacher, Frédéric, Hocini, Mélèze, Jaïs, Pierre, Derval, Nicolas, Bortone, Agustín, Boveda, Serge, Denis, Arnaud, Haïssaguerre, Michel, and Albenque, Jean-Paul

Published
2018
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11. Pulmonary vein isolation alone or in combination with substrate modulation after electrical cardioversion failure in patients with persistent atrial fibrillation: The PACIFIC trial: Study design.

Author

Bortone, Agustín Alfonso, Marijon, Eloi, Limite, Luca Rosario, Lagrange, Philippe, Brigadeau, François, Martins, Raphaël, Durand, Cyril, and Albenque, Jean‐Paul

Subjects
*RESEARCH, *CONFIDENCE intervals, *ATRIAL fibrillation, *CATHETER ablation, *MANN Whitney U Test, *DISEASE relapse, *TREATMENT failure, *TREATMENT effectiveness, *RANDOMIZED controlled trials, *SEVERITY of illness index, *T-test (Statistics), *DESCRIPTIVE statistics, *STATISTICAL hypothesis testing, *RESEARCH funding, *PULMONARY veins, *ELECTRIC countershock, *COMBINED modality therapy, *STATISTICAL sampling, *DATA analysis software, *RECEIVER operating characteristic curves, *SENSITIVITY & specificity (Statistics), *LONGITUDINAL method
Abstract

Introduction: Pulmonary vein isolation (PVI) is effective at treating 50% of unselected patients with persistent atrial fibrillation (AF). Alternatively, PVI combined with a new ablation strategy entitled the Marshall‐PLAN ensures a 78% 1‐year sinus rhythm (SR) maintenance rate in the same population. However, a substantial subset of patients could undergo the Marshall‐PLAN unnecessarily. It is therefore essential to identify those patients who can be treated with PVI alone versus those who may truly benefit from the Marshall‐PLAN before ablation is performed. In this context, we hypothesized that electrical cardioversion (EC) could help to select the most appropriate strategy for each patient. Methods: In this multicentre, prospective, randomized study, patients with AF recurrence within 4 weeks after EC will be randomized 1:1 to PVI alone or the Marshall‐PLAN. Conversely, patients in whom SR is maintained for ≥4 weeks after EC will be treated with PVI only and included in a prospective registry. The primary endpoint will be the 1‐year SR maintenance rate after a single ablation procedure. Results and Conclusion: The Marshall‐PLAN might be necessary in patients with an advanced degree of persistent AF (i.e., where SR is not maintained for ≥4 uninterrupted weeks after EC). Conversely, in patients with mild or moderate persistent AF (i.e., where SR is maintained for ≥4 weeks after EC), PVI alone might be a sufficient ablation strategy. The PACIFIC trial is the first study designed to assess whether rhythm monitoring after EC could help to identify patients who should undergo adjunctive ablation strategies beyond PVI. [ABSTRACT FROM AUTHOR]

Published
2023
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30. Atrial fibrillation and its determinants after radiofrequency ablation of chronic common atrial flutter

Author

Cade, Stéphane, Sedighian, Shahine, Bortone, Agustin, Gervasoni, Richard, Macia, Jean Christophe, Leclercq, Florence, Grolleau, Robert, Pasquié, Jean Luc, Singh, Balbir, Lokhandwala, Yash, Francis, Johnson, and Gupta, Anup

Subjects
JOURNALS: Indian Pacing and Electrophysiology Journal, Indian Pacing and Electrophysiology Journal
Abstract

Aim. Atrial fibrillation (AFib) is a major clinical issue and its occurrence is the main problem after catheter ablation of atrial flutter. The long-term occurrence of AFib after common atrial flutter ablation is still matter of debate as it may influence the therapeutic approach. So, the aim of our study was to analyze the determinants and the time course of AFib after radiofrequency catheter ablation of chronic common atrial flutter. Methods and Results. 89 consecutive patients (67.5 ± 12.0 yrs) underwent RF ablation of chronic common atrial flutter. 38.2 % had previous history of paroxysmal AFib. 51% had no underlying structural heart disease. Over a mean follow-up of 38 ± 13 months, the occurrence rate of AFib progressively increased up to 32.9% at the end of follow-up. The median occurrence time for AFib was 8 months. AFib occurrence was significantly associated with previous AFib history (P=0.01) but not with the presence of underlying heart disease (P=n.s.). Of particular interest, in our study, AFib never occurred in patients without previous AFib history. Palpitations after chronic common atrial flutter ablation was mostly related to AFib. Conclusion. In conclusion, after chronic common atrial flutter ablation, AFib incidence progressively increased over the follow-up in all patients. Patients with prior AFib history appeared to be a very high risk group. In these patients, closer monitoring is mandatory and the persistent risk of AFib recurrences may justify prolonged anticoagulation policy.

Published
2005

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