488 results on '"Boren, Jan"'
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2. Synthesis of novel tetrahydrobenzo[b]thiophene-3-carbonitrile (THBTC)-based heterocycles: Structural insights, reactivity profiles, and in-silico bioactivity studies
3. Extracellular vesicles transport RNA between cells: Unraveling their dual role in diagnostics and therapeutics
4. Synthesis, spectroscopic characterization, DFT and molecular docking of N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl) naphthalene-1-sulfonamide derivatives
5. Design and synthesis of novel JNK inhibitors targeting liver pyruvate kinase for the treatment of non-alcoholic fatty liver disease and hepatocellular carcinoma
6. Adipocyte PI3K links adipostasis with baseline insulin secretion at fasting through an adipoincretin effect
7. Sulfone-based human liver pyruvate kinase inhibitors – Design, synthesis and in vitro bioactivity
8. Non-coronary peripheral arterial complications in people with type 2 diabetes: a Swedish retrospective cohort study
9. Non-coronary arterial outcomes in people with type 1 diabetes mellitus: a Swedish retrospective cohort study
10. ANGPTL3 Downregulation Increases Intracellular Lipids by Reducing Energy Utilization
11. High levels of lipoprotein(a) in transgenic mice exacerbate atherosclerosis and promote vulnerable plaque features in a sex-specific manner
12. The acute effect of different NAD+ precursors included in the combined metabolic activators
13. Longitudinal metabolomics analysis reveals the acute effect of cysteine and NAC included in the combined metabolic activators
14. Cerebrospinal fluid sulfatide isoforms lack diagnostic utility in separating progressive from relapsing-remitting multiple sclerosis
15. AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity
16. Metabolism of Triglyceride-Rich Lipoproteins
17. Tuning liver pyruvate kinase activity up or down with a new class of allosteric modulators
18. Abstract 16780: Single Cell Profiles of Human Heart Failure and Myocardial Diseases
19. Twenty Years of Cardiovascular Complications and Risk Factors in Patients With Type 2 Diabetes: A Nationwide Swedish Cohort Study
20. Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning
21. Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats.
22. Anthraquinone derivatives as ADP-competitive inhibitors of liver pyruvate kinase
23. Prediction of drug candidates for clear cell renal cell carcinoma using a systems biology-based drug repositioning approach
24. Revisiting the role of serine metabolism in hepatic lipogenesis
25. A network-based approach reveals the dysregulated transcriptional regulation in non-alcoholic fatty liver disease
26. Intussusceptive Angiogenesis in Human Metastatic Malignant Melanoma
27. Cholesterol efflux promoting function of high-density lipoproteins in calcific aortic valve stenosis
28. Stratification of patients with clear cell renal cell carcinoma to facilitate drug repositioning
29. The C. elegans PAQR-2 and IGLR-2 membrane homeostasis proteins are uniquely essential for tolerating dietary saturated fats
30. Extensive transcription mis-regulation and membrane defects in AdipoR2-deficient cells challenged with saturated fatty acids
31. Systems biology based drug repositioning for development of cancer therapy
32. Lipid profiling of human diabetic myocardium reveals differences in triglyceride fatty acyl chain length and degree of saturation
33. Current Status of COVID-19 Therapies and Drug Repositioning Applications
34. A systems biology approach for studying neurodegenerative diseases
35. Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
36. Classification of clear cell renal cell carcinoma based on PKM alternative splicing
37. Lipid droplet-associated kinase STK25 regulates peroxisomal activity and metabolic stress response in steatotic liver
38. Quantifying atherogenic lipoproteins for lipid-lowering strategies: Consensus-based recommendations from EAS and EFLM
39. Rare dyslipidaemias, from phenotype to genotype to management: a European Atherosclerosis Society task force consensus statement
40. Impact of proprotein convertase subtilisin/kexin type 9 inhibition with evolocumab on the postprandial responses of triglyceride-rich lipoproteins in type II diabetic subjects
41. Discovery of Cell-Permeable Allosteric Inhibitors of Liver Pyruvate Kinase: Design and Synthesis of Sulfone-Based Urolithins
42. Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
43. Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia
44. Systems biology perspective for studying the gut microbiota in human physiology and liver diseases
45. AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of adiponectin
46. Integrative Proteo-Transcriptomic Characterization of Advanced Fibrosis in Chronic Liver Disease Across Etiologies
47. Multi-Tissue Network Analysis Reveals the Effect of JNK Inhibition on Dietary Sucrose-Induced Metabolic Dysfunction in Rats
48. Localised lipid accumulation detected in infarcted mouse heart tissue using ToF-SIMS
49. Pyruvate kinase L/R is a regulator of lipid metabolism and mitochondrial function
50. Predicting troponin biomarker elevation from electrocardiograms using a deep neural network.
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