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1. Global access to quality-assured medical products: the Oxford Statement and call to action

Author

Paul N Newton, Katherine C Bond, Paul Newton, Katherine Bond, Victor Abiola, Khadijah Ade-Abolade, Moji Adeyeye, Aria Ahmad, Tahani Ahmed, Pablo Alcocer Vera, Marie Amsilli, Marie Antignac, Chimezie Anyakora, Ayenew Ashenef, Adam Aspinall, Ghulam Rahim Awab, Zaheer-Ud-Din Babar, Wilbert Bannenberg, Jon Bastow, Carine Baxerres, Fred Behringer, Daniel Bempong, Chris Bird, Phonepasith Boupha, Kem Boutsamay, Jason Bower, Beth Boyer, Hazel Bradley, Joel Breman, Céline Caillet, Kashi Barbara Carasso, Phaik Yeong Cheah, Lester Chinery, Aubrey Clark, Erin Coonahan, Rachel Cooper, Philip Coyne, Andre Daher, Nicholas Day, Olivier De Santi, Fulgence Djorou Kouame, Kim Doyle, Ines du Plessis, Catherine Dujardin, Chioma Ejekam, Latifa El Hadri, Facundo Fernandez, Alessandra Ferrario, Clark Freifeld, Assma Gafur Omargy, Naira Mohamed Ali Ghanem, Marie Gill, Mike Grijseels, Philippe Guerin, Nhomsai Hagen, Heather Hamill, Georgina Joan Harigwo, Amalia Hasnida, Matthew Hassett, Cathrin Hauk, Lutz Heide, Peter Horby, Tsatsral Ichinkhorloo, Mike Isles, Richard Wilhelm Otto Jähnke, Alice Jamieson, Roslyn Jones, Tomoko Kakio, Mohga Kamal-Yanni, Harparkash Kaur, Pierre Claver Kayumba, Irina Kazaryan, Matthew Keller, Kalynn Kennon, Felix Khuluza, Stephen Kigera, Kazuko Kimura, Patricia Kingori, Joseph Kitukulu, Tineke Kleinhout-Vliek, Chaitanya Koduri, Maarten Kok, Mirza Lalani, Marie Lamy, Marya Lieberman, Rui Liu, Paul Lotay, Nantasit Luangasanatip, Murray Lumpkin, Susanne Lundin, Tim Mackey, Keiko Maekawa, Marissa Malchione, Boravann Mam, Roland Marini Djang'eing'a, Aronrag Meeyai, Talieh Mirsalehi, Gamal Mohamed Ali, Andria Mousa, Mirfin Mpundu, Immaculee Mukankubito, Ambwene Mwakalobo, Sheilah Catherine Nabukeera, Kris Natarajan, Bernard Naughton, Theophilus Ndorbor, Ariadna Nebot, Phillip Nguyen, Adina-Loredana Nistor, Bah Ngoh Nyaah Fidelis, Piero Olliaro, Eugenia Olliaro, Alberto Olliaro, Kenneth Onu, Sophie Ouvrard, Sachiko Ozawa, Michael Parker, Koray Parmaksiz, Anushka Patel, Daniel Pawson, Andrew Payne, Koen Peeters Grietens, Elizabeth Pettit, Souly Phanouvong, Elizabeth Pisani, Aline Plançon, Oksana Pyzik, Lembit Rägo, Mohammad Sofiqur Rahman, Eurek Ranjit, Raffaella Ravinetto, Joseph M. Redd, David Richmond, Pierre-Yves Sacré, Simon Schäfermann, Sauman Singh, Tariro Sithole, Andrea Stewart, Anita Svadzian, Patricia Tabernero, Fatima Tauqeer, Fiona Theunissen, Emmanuel Yaovi Tossou, Zahra Anita Trippe, Farouk Umaru, Ali Umoru, Serena Vickers, Vayouly Vidhamaly, Andrea Vogt, Lisa White, Nicholas White, Benjamin Wilson, Veronika J. Wirtz, Jessie Hui Zhen Wong, Owen Wood, Jing Xu, Jingying Xu, Shunmay Yeung, Muhammad Zaman, Monique Zambo Biloa, and Zuzaan Zulzaga

Subjects
Statement (computer science), business.industry, media_common.quotation_subject, MEDLINE, Developing country, General Medicine, Public relations, Global Health, Health Services Accessibility, United Kingdom, Call to action, Pharmaceutical Preparations, Global health, Humans, Quality (business), business, Developing Countries, media_common
Published
2019

2. The quality of antimalarial medicines in western Cambodia: a case study along the Thai-Cambodian border

Author

Souly, Phanouvong, Christopher, Raymond, Laura, Krech, Yanga, Dijiba, Boravann, Mam, Patrick, Lukulay, Duong, Socheat, Tey, Sovannarith, and Chroeng, Sokhan

Subjects
Antimalarials, Cross-Sectional Studies, Public Sector, Health Personnel, Biological Availability, Humans, Technology, Pharmaceutical, Drug Therapy, Combination, Private Sector, Malaria, Falciparum, Cambodia, Thailand, Health Services Accessibility
Abstract

The prevalence, availability, and use of antimalarial medicines (AMLs) were studied in six Cambodian provinces along the Thai-Cambodian border. The study was divided into two parts: the first looked at the quality of AMLs available in Pursat, Pailin, Battambang, Bantey Meanchey, Oddar Meanchey, and Preah Vihear and the second obtained information about the availability and use of AMLs. A randomized sampling methodology was used to select locations and collect samples, which were screened using Global Pharma Health Fund (GPHF) Minilabs. A subset of samples was sent to quality control laboratories for confirmatory testing. For the second part of the study, face-to-face interviews were conducted using standardized surveys with members of randomly selected households and staff of health facilities in the villages with highest malaria incidence to find out where they acquired their AMLs and which were most frequently used. The results showed an overall failure rate of 12.3% (n = 46 of 374 total AML samples). The causes of medication sample failure were low active pharmaceutical ingredient (API) content, failed dissolution properties, and unacceptably high levels of impurities. A total of 86.2% of survey respondents (n = 1,648 of 1,912) reported a member of their household having malaria in the previous year. The most commonly used medicines were paracetamol (67.1% of respondents), Malarine (A+M co-blistered, 28.6%), artesunate + mefloquine co-blistered (public sector product, 17.3%), quinine (16.7%), and artesunate monotherapy (11.9%). Health staff typically prescribed co-blistered artesunate plus mefloquine in the public sector (67.8%), the artesunate plus mefloquine "social marketing" product from Population Services International (PSI), Malarine (50.3%) in the private sector, artemether (49.7%), chloroquine (39%) and paracetamol (72.9%) to reduce fever.

Published
2013

3. Collaborative Health and Enforcement Operations on the Quality of Antimalarials and Antibiotics in Southeast Asia

Author

Yong, Yuk Lin, primary, Plançon, Aline, additional, Lau, Yen Hui, additional, Hostetler, Dana M., additional, Fernández, Facundo M., additional, Green, Michael D., additional, Sounvoravong, Sourisak, additional, Nara, Suon, additional, Boravann, Mam, additional, Dumrong, Thitikornkovit, additional, Bangsawan, Nurjaya, additional, Low, Min Yong, additional, Lim, Chin-Chin, additional, Ai, Ruth Lee Choo, additional, and Newton, Paul N., additional

Published
2015
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4. Quality of Antimalarials at the Epicenter of Antimalarial Drug Resistance: Results from an Overt and Mystery Client Survey in Cambodia

Author

Yeung, Shunmay, primary, Lawford, Harriet L. S., additional, Tabernero, Patricia, additional, Nguon, Chea, additional, van Wyk, Albert, additional, Malik, Naiela, additional, DeSousa, Mikhael, additional, Rada, Ouk, additional, Boravann, Mam, additional, Dwivedi, Prabha, additional, Hostetler, Dana M., additional, Swamidoss, Isabel, additional, Green, Michael D., additional, Fernandez, Facundo M., additional, and Kaur, Harparkash, additional

Published
2015
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