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180 results on '"Bonfiglio, C."'

1. Determinants of weight, psychological status, food contemplation and lifestyle changes in patients with obesity during the COVID-19 lockdown: a nationwide survey using multiple correspondence analysis

Author

Caretto, A., Pintus, S., Petroni, M. L., Osella, A. R., Bonfiglio, C., Morabito, S., Zuliani, P., Sturda, A., Castronuovo, M., Lagattolla, V., Maghetti, A., Lapini, E., Bianco, A. M., Cisternino, M., Cerutti, N., Mulas, C. A., Hassan, O., Cardamone, N., Parillo, M., and Sonni, L.

Published
2022
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3. The role of EZH2 and H3K27me3 epigenetic signature in modulating T-cell polarization in atherosclerosis

Author

Bonfiglio, C A, primary, Lacy, M, additional, Janjic, A, additional, Avcilar Kucukgoze, I, additional, Nitz, K, additional, Wu, Y, additional, Wange, L E, additional, Santovito, D, additional, Bosmans, L A, additional, Imhof, A, additional, Enard, W, additional, Weber, C, additional, De Winther, M, additional, Lutgens, E, additional, and Atzler, D, additional

Published
2023
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4. PO-1172 Sarcopenia in oropharyngeal cancer treated with curative radiotherapy: time for a tailored approach?

Author

Bergamaschi, L., primary, Zaffaroni, M., additional, Vincini, M.G., additional, Marvaso, G., additional, Volpe, S., additional, Colombo, F., additional, Bonfiglio, C., additional, Zorzi, S., additional, Cossu Rocca, M., additional, Sabbatini, A., additional, Cannillo, G., additional, Zagallo, E., additional, Ansarin, M., additional, Orecchia, R., additional, Alterio, D., additional, and Jereczek-Fossa, B., additional

Published
2023
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8. Immunotherapy and cardiovascular diseases: novel avenues for immunotherapeutic approaches.

Author

Bonfiglio, C A, Weber, C, Atzler, D, and Lutgens, E

Subjects
*CARDIOVASCULAR diseases, *IMMUNOTHERAPY, *INFLAMMATION, *CLINICAL trials
Abstract

As current therapies for cardiovascular disease (CVD), predominantly based on lipid lowering, still face an unacceptable residual risk, novel treatment strategies are being explored. Besides lipids, inflammatory processes play a major role in the pathogenesis of atherosclerosis, the underlying cause of the majority of CVD. The first clinical trials targeting the interleukin-1β-inflammasome axis have shown that targeting this pathway is successful in reducing cardiovascular events but did not decrease overall CVD mortality. Hence, novel and improved immunotherapeutics to treat CVD are being awaited. [ABSTRACT FROM AUTHOR]

Published
2023
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10. PO-1088 Toxicity Profile Of 100 Oropharyngeal Cancer Patients Treated With Modern Approaches

Author

Alrerio, D., primary, Corrao, G., additional, Zorzi, S., additional, Agostini, G., additional, Marvaso, G., additional, Volpe, S., additional, Bergamaschi, L., additional, Pedone, C., additional, Franzetti, J., additional, Bonfiglio, C., additional, Camarda, A.M., additional, Tagliabue, M., additional, Cossu Rocca, M., additional, Ansarin, M., additional, and Jereczek-Fossa, B.A., additional

Published
2022
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11. Serum Folate deficiency in HCV related Hepatocellular Carcinoma

Author

Malaguarnera, G., Catania, V. E., Bertino, G., Drago, F., Madeddu, R., Bonfiglio, C., and Malaguarnera, M.

Subjects
Liver Cirrhosis, Multidisciplinary, Carcinoma, Hepatocellular, Liver Neoplasms, Hepacivirus, Hepatitis C, Chronic, Cancer metabolism, Hepatitis C, digestive system diseases, Cancer metabolism, Cancer, Liver cancer, HCC, Folic Acid, Humans, RNA, HCC, Liver cancer, Homocysteine, Cancer
Abstract

Nutritional and environmental factors had been reporting in the progression of hepatocellular carcinoma (HCC). In this study, we focused our intervention in the correlation between the folate status and the progression of HCC in patients with chronic virus C (HCV) infection. Nine-eight patients, HCV positive with HCC and one hundred of patients with HCV positive liver cirrhosis (LC) and one hundred patients with HCV positive chronic hepatitis (CHC) and one hundred control subjects were enrolled. The viremia for hepatitis C patients (HCV) was determined by HCV RNA with polymerase chain reaction. HCV was confirmed by HCV RNA or a positive anti-HCV test with chronic liver disease. The comparison of folate serum levels in HCC patients vs Liver Cirrhosis (LC) patients showed a significant decrease of 1.16 ng/ml P = 0.0006 (95% CI-1.925 to − 0.395), in HCC patients versus CHC a decrease of 1.40 ng/ml P P P P P

Published
2021

16. PD-0656: A contouring atlas on MRI of emerging pelvic female organs at risk for daily practice radiotherapy

Author

Allajbej, A., primary, Patani, F., additional, Gasparini, L., additional, Di Guglielmo, F.C., additional, Bonfiglio, C., additional, Fasciolo, D., additional, Rosa, C., additional, Trignani, M., additional, Vinciguerra, A., additional, Caravatta, L., additional, Di Tommaso, M., additional, Cianci, R., additional, Basilico, R., additional, Augurio, A., additional, and Genovesi, D., additional

Published
2020
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19. Reducing NAFLD-screening time: A comparative study of eight diagnostic methods offering an alternative to ultrasound scans

Author

Procino, F., Misciagna, G., Veronese, N., Caruso, M. G., Chiloiro, M., Cisternino, A. M., Notarnicola, M., Bonfiglio, C., Bruno, I., Buongiorno, C., Campanella, A., Deflorio, V., Franco, I., Guerra, R., Leone, C. M., Mirizzi, A., Nitti, A., Osella, A. R., MICOL GROUP, Procino, F., Misciagna, G., Veronese, N., Caruso, M.G., Chiloiro, M., Cisternino, A.M., Notarnicola, M., Bonfiglio, C., Bruno, I., Buongiorno, C., Campanella, A., Deflorio, V., Franco, I., Guerra, R., Leone, C.M., Mirizzi, A., Nitti, A., Osella, A.R., and MICOL GROUP

Subjects
Adult, Male, medicine.medical_specialty, Diagnostic methods, Waist, Gastroenterology, Body Mass Index, 03 medical and health sciences, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Risk Factors, Internal medicine, Screening method, Medicine, Humans, Aged, Ultrasonography, Hepatology, Anthropometry, business.industry, Waist-Hip Ratio, Fatty liver, Ultrasound, nutritional and metabolic diseases, Percentage reduction, Middle Aged, medicine.disease, screening NAFLD, Italy, ROC Curve, 030220 oncology & carcinogenesis, 030211 gastroenterology & hepatology, Female, Steatosis, Waist Circumference, business, Body mass index
Abstract

Background & Aims: The use of ultrasound scan (US) in non-alcoholic fatty liver disease (NAFLD) screening overloads US waiting lists. We hypothesized and tested a hybrid two-step method, consisting of applying a formula, to exclude subjects at low risk, before US. Methods: The sample included 2970 males and females (937 with NAFLD) diagnosed by US. We selected eight formulas: Fatty Liver Index (FLI), Hepatic Steatosis Index (HIS), body mass index (BMI), waist circumference (WC), Abdominal Volume Index (AVI), waist-to-height ratio (WHtR), waist/height0.5 (WHT.5R) and Body Roundness Index (BRI), and calculated their performance in the two-step method evaluating percentage reduction of the number of liver US (US reduction percentage), percentage of false negative and percentage of NAFLD identified. Results: The US reductions percentage were 52.2% (WHtR), 52.1% (HIS), 51.8% (FLI), 50.8% (BRI), 50.7% (BMI and WHt_5R), 46.5% (WC) and 45.2% (AVI). The false negative percentage were 8.5% (WHtR), 7.9% (BRI), 7.3% (WHt_5R), 7.2% (BMI), 6.7% (HIS), 6.6% (FLI), 5.6% (WC) and 5.2% (AVI). The best percentage of NALFD identified was obtained using AVI (83.6%) before US, then WC (82.2%), FLI (79%), HIS (78.9%), BMI (77.3%), WHt_5R (76.9%), BRI (74.8%) and WHtR (73%). Conclusion: The best formula to use in two-step diagnostic NAFLD screening was AVI, which showed a low false negative rate and a higher percentage of identified NAFLD. Other studies evaluating the economic advantages of this screening method are warranted. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd

Published
2018

21. Coffee Intake and Liver Steatosis: A Population Study in a Mediterranean Area

Author

Veronese, N., Notarnicola, M., Cisternino, A. M., Reddavide, R., Inguaggiato, R., Guerra, V., Rotolo, O., Zinzi, I., Leandro, G., Correale, M., Tutino, V., Misciagna, G., Osella, A. R., Bonfiglio, C., Giannelli, G., Caruso, M. G., The MICOL Group, Veronese, N., Notarnicola, M., Cisternino, A.M., Reddavide, R., Inguaggiato, R., Guerra, V., Rotolo, O., Zinzi, I., Leandro, G., Correale, M., Tutino, V., Misciagna, G., Osella, A.R., Bonfiglio, C., Giannelli, G., Caruso, M.G., and The MICOL Group

Subjects
Male, Cross-sectional study, Blood Pressure, Gastroenterology, Body Mass Index, chemistry.chemical_compound, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Surveys and Questionnaires, Prevalence, caffeine, Aged, 80 and over, Nutrition and Dietetics, ultrasound, Mediterranean Region, Fatty liver, Middle Aged, 3. Good health, Italy, 030220 oncology & carcinogenesis, Population study, 030211 gastroenterology & hepatology, epidemiology, Female, Waist Circumference, Caffeine, lcsh:Nutrition. Foods and food supply, Fatty Liver, Alcoholic, Adult, medicine.medical_specialty, Alcohol Drinking, coffee, lcsh:TX341-641, Article, 03 medical and health sciences, Internal medicine, medicine, Humans, fatty liver, Aged, business.industry, Odds ratio, medicine.disease, Cross-Sectional Studies, Logistic Models, chemistry, Alcoholic fatty liver, Steatosis, business, Body mass index, Food Science
Abstract

Coffee drinking seems to have several beneficial effects on health outcomes. However, the effect on hepatic steatosis, depending on a high alcohol consumption (AFLD, alcoholic fatty liver disease) or on metabolic factors (non-alcoholic fatty liver disease, NAFLD), is still equivocal. Thus, we aimed to explore the potential association between coffee consumption and the presence and severity of hepatic steatosis in people with NAFLD or AFLD. In this cross-sectional study, coffee drinking was recorded using a semi-quantitative food frequency questionnaire, and categorized as yes vs. no and as 0, 1, 2, ≥3. The degree of fatty liver was assessed through a standardized ultrasound examination (score 0 to 6, with higher values reflecting higher severity). Liver steatosis was classified as NAFLD or AFLD on daily alcohol intake >30 g/day for men and >20 g/day for women. This study included 2819 middle-aged participants, the great majority were coffee drinkers (86.1%). After adjusting for 12 potential confounders, drinking coffee was not associated with decreased odds for NAFLD (n = 916) (odds ratio, OR = 0.93, 95% confidence intervals, CI: 0.72-1.20) or AFLD (n = 276) (OR = 1.20, 95% CI: 0.66-2.0). The consumption of coffee (categorized as yes vs. no), or an increased consumption of coffee were not associated with the presence of mild, moderate or severe liver steatosis in either NAFLD or AFLD. In conclusion, coffee intake was not associated with any lower odds of hepatic steatosis in either non-alcoholic or alcoholic forms in this large cohort of South Italian individuals. © 2018 by the authors. Licensee MDPI, Basel, Switzerland.

Published
2018
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24. Educational level influenced the gold standard diagnosis of late-life depression in the GreatAGE study

Author

Lozupone, M., primary, Veneziani, F., additional, Lofano, L., additional, Galizia, I., additional, Stella, E., additional, Copetti, M., additional, Arcuti, S., additional, Leo, A., additional, Sardone, R., additional, Grasso, A., additional, Tursi, M., additional, Barulli, M.R., additional, Tortelli, R., additional, Capozzo, R., additional, Panza, F., additional, Seripa, D., additional, Bonfiglio, C., additional, Osella, A.R., additional, and Logroscino, G., additional

Published
2017
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25. Swallowing Disturbances and Psychiatric Profile in Older Adults: The GreatAGE Study

Author

Lozupone, M., primary, Leo, A., additional, Sardone, R., additional, Veneziani, F., additional, Bonfiglio, C., additional, Galizia, I., additional, Lofano, L., additional, Grasso, A., additional, Tursi, M., additional, Barulli, M.R., additional, Capozzo, R., additional, Tortelli, R., additional, Panza, F., additional, Seripa, D., additional, Osella, A.R., additional, and Logroscino, G., additional

Published
2017
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26. Effect of a low glycemic index Mediterranean diet on non-alcoholic fatty liver disease. A randomized controlled clinici trial

Author

Misciagna, G., primary, del Pilar Díaz, M., additional, Caramia, D. V., additional, Bonfiglio, C., additional, Franco, I., additional, Noviello, M. R., additional, Chiloiro, M., additional, Abbrescia, D. I., additional, Mirizzi, A., additional, Tanzi, M., additional, Caruso, M. G., additional, Correale, M., additional, Reddavide, R., additional, Inguaggiato, R., additional, Cisternino, A. M., additional, and Osella, Alberto Rubén, additional

Published
2016
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27. Validity of the Geriatric Depression Scale-30 against the gold standard diagnosis of depression in older age: The GreatAGE Study

Author

Lozupone, M., primary, Veneziani, F., additional, Galizia, I., additional, Lofano, L., additional, Montalbò, D., additional, Arcuti, S., additional, Tortelli, R., additional, Barulli, M.R., additional, Capozzo, R., additional, Bonfiglio, C., additional, Panza, F., additional, Seripa, D., additional, Todarello, O., additional, and Logroscino, G., additional

Published
2016
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32. SUICIDIO MEDIANTE PRECIPITAZIONE

Author

Brancato, A, Cascio, O, Geraci, Diego, Bonfiglio, C, Casamichela, G, and Teodoro, M.

Subjects
ACCIDENTE, PRECIPITAZIONE, SUICIDIO
Published
2012

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