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1. Stereotactic ultrahypofractionated MR-guided radiotherapy for localized prostate cancer – Acute toxicity and patient-reported outcomes in the prospective, multicenter SMILE phase II trial

Author

Fink, C.A., Ristau, J., Buchele, C., Klüter, S., Liermann, J., Hoegen-Saßmannshausen, P., Sandrini, E., Lentz-Hommertgen, A., Baumann, L., Andratschke, N., Baumgartl, M., Li, M., Reiner, M., Corradini, S., Hörner-Rieber, J., Bonekamp, D., Schlemmer, H.-P., Belka, C., Guckenberger, M., Debus, J., and Koerber, S.A.

Published
2024
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2. Stereotactic ultrahypofractionated MR-guided radiotherapy for localized prostate cancer - Acute toxicity and patient-reported outcomes in the prospective, multicenter SMILE phase II trial

Author

Fink, C A, Ristau, J, Buchele, C, Klüter, S, Liermann, J, Hoegen-Saßmannshausen, P, Sandrini, E, Lentz-Hommertgen, A, Baumann, L, Andratschke, N, Baumgartl, M, Li, M, Reiner, M, Corradini, S, Hörner-Rieber, J, Bonekamp, D, Schlemmer, H-P, Belka, C, Guckenberger, M, Debus, J, Koerber, S A, Fink, C A, Ristau, J, Buchele, C, Klüter, S, Liermann, J, Hoegen-Saßmannshausen, P, Sandrini, E, Lentz-Hommertgen, A, Baumann, L, Andratschke, N, Baumgartl, M, Li, M, Reiner, M, Corradini, S, Hörner-Rieber, J, Bonekamp, D, Schlemmer, H-P, Belka, C, Guckenberger, M, Debus, J, and Koerber, S A

Abstract

BACKGROUND Due to superior image quality and daily adaptive planning, MR-guided stereotactic body radiation therapy (MRgSBRT) has the potential to further widen the therapeutic window in radiotherapy of localized prostate cancer. This study reports on acute toxicity rates and patient-reported outcomes after MR-guided adaptive ultrahypofractionated radiotherapy for localized prostate cancer within the prospective, multicenter phase II SMILE trial. MATERIALS AND METHODS A total of 69 patients with localized prostate cancer underwent MRgSBRT with daily online plan adaptation. Inclusion criteria comprised a tumor stage ≤ T3a, serum PSA value ≤ 20 ng/ml, ISUP Grade group ≤ 4. A dose of 37.5 Gy was prescribed to the PTV in five fractions on alternating days with an optional simultaneous boost of 40 Gy to the dominant intraprostatic lesion defined by multiparametric MRI. Acute genitourinary (GU-) and gastrointestinal (GI-) toxicity, as defined by CTCAE v. 5.0 and RTOG as well as patient-reported outcomes according to EORTC QLQ-C30 and -PR25 scores were analyzed at completion of radiotherapy, 6 and 12 weeks after radiotherapy and compared to baseline symptoms. RESULTS There were no toxicity-related treatment discontinuations. At the 12-week follow-up visit, no grade 3 + toxicities were reported according to CTCAE. Up until the 12-week visit, in total 16 patients (23 %) experienced a grade 2 GU or GI toxicity. Toxicity rates peaked at the end of radiation therapy and subsided within the 12-week follow-up period. At the 12-week follow-up visit, no residual grade 2 GU toxicities were reported and 1 patient (1 %) had residual grade 2 enteritic symptoms. With exception to a significant improvement in the emotional functioning score following MRgSBRT, no clinically meaningful changes in the global health status nor in relevant subscores were reported. CONCLUSION Daily online-adaptive MRgSBRT for localized prostate cancer resulted in an excellent overall toxicity profile without a

Published
2024

6. Mutant KIT as imatinib-sensitive target in metastatic sinonasal carcinoma

Author

Dieter, S.M., Heining, C., Agaimy, A., Huebschmann, D., Bonekamp, D., Hutter, B., Ehrenberg, K.R., Fröhlich, M., Schlesner, M., Scholl, C., Schlemmer, H.-P., Wolf, S., Mavratzas, A., Jung, C.S., Gröschel, S., von Kalle, C., Eils, R., Brors, B., Penzel, R., Kriegsmann, M., Reuss, D.E., Schirmacher, P., Stenzinger, A., Federspil, P.A., Weichert, W., Glimm, H., and Fröhling, S.

Published
2017
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7. Abstract No. 9 ▪ FEATURED ABSTRACT Pivotal Study of Magnetic Resonance Imaging-Guided Transurethral Ultrasound Ablation (TULSA) of the Prostate: 4-year Follow-up

Author

Raman, S., primary, Arora, S., additional, Macura, K., additional, Oto, A., additional, Futterer, J., additional, Staruch, R., additional, Tirkes, T., additional, Bonekamp, D., additional, Haider, M., additional, Cool, D., additional, Nandalur, K., additional, Nicolau, C., additional, Costa, D., additional, Persigehl, T., additional, Clarke, G., additional, Chin, J., additional, Klotz, L., additional, and Eggener, S., additional

Published
2023
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9. Abstract No. 111 ▪ FEATURED ABSTRACT Pivotal trial of MRI-guided transurethral ultrasound ablation in men with localized prostate cancer: three-year follow-up

Author

Raman, S., primary, Arora, S., additional, Macura, K., additional, Oto, A., additional, Fütterer, J., additional, Staruch, R., additional, Tirkes, T., additional, Bonekamp, D., additional, Haider, M., additional, Cool, D., additional, Nandalur, K., additional, Nicolau, C., additional, Costa, D., additional, Persigehl, T., additional, Beserra, A., additional, Chin, J., additional, Klotz, L., additional, and Eggener, S., additional

Published
2022
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11. Detection of significant prostate cancer using target saturation in transperineal magnetic resonance imaging/transrectal ultrasonography–fusion biopsy: A prospective, randomized comparison to conventional target biopsy

Author

Saner, Y., primary, Wiesenfarth, M., additional, Tschirdewahn, S., additional, Püllen, L., additional, Bonekamp, D., additional, Krafft, U., additional, Kesch, C., additional, Darr, C., additional, Forsting, M., additional, Umutlu, L., additional, Hadaschik, B.A., additional, and Radtke, J.P., additional

Published
2021
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13. Reply by Authors - Magnetic Resonance Imaging-Guided Transurethral Ultrasound Ablation of Prostate Cancer

Author

Klotz, L., Pavlovich, C.P., Chin, J., Hatiboglu, G., Koch, M., Penson, D., Raman, S., Oto, A., Futterer, J.J., Serrallach, M., Relle, J., Lotan, Y., Heidenreich, A., Bonekamp, D., Haider, M., Tirkes, T., Arora, S., Macura, K.J., Costa, D.N., Persigehl, T., Pantuck, A.J., Bomers, J., Burtnyk, M., Staruch, R., Eggener, S., Klotz, L., Pavlovich, C.P., Chin, J., Hatiboglu, G., Koch, M., Penson, D., Raman, S., Oto, A., Futterer, J.J., Serrallach, M., Relle, J., Lotan, Y., Heidenreich, A., Bonekamp, D., Haider, M., Tirkes, T., Arora, S., Macura, K.J., Costa, D.N., Persigehl, T., Pantuck, A.J., Bomers, J., Burtnyk, M., Staruch, R., and Eggener, S.

Abstract

Contains fulltext : 232934.pdf (Publisher’s version ) (Closed access)

Published
2021

17. MRT/TRUS-Fusionsbiopsie der Prostata - die Saturation der tumorsuspekten Läsion verbessert die Detektionsrate gezielter Biopsien signifikant

Author

Tschirdewahn, S, Bonekamp, D, Wiesenfarth, M, Harke, N, Kesch, C, Püllen, L, Guberina, N, Reis, H, Grünwald, V, Giganti, F, Forsting, M, Wetter, A, Hadaschik, BA, Radtke, JP, Tschirdewahn, S, Bonekamp, D, Wiesenfarth, M, Harke, N, Kesch, C, Püllen, L, Guberina, N, Reis, H, Grünwald, V, Giganti, F, Forsting, M, Wetter, A, Hadaschik, BA, and Radtke, JP

Published
2020

19. The value of PSA density in PI-RADS 3 lesions on multiparametric MRI - a strategy to avoid unnecessary prostate biopsies

Author

Görtz, M., primary, Radtke, J.P., additional, Hatiboglu, G., additional, Schütz, V., additional, Tosev, G., additional, Güttlein, M., additional, Leichsenring, J., additional, Stenzinger, A., additional, Bonekamp, D., additional, Schlemmer, H., additional, Hohenfellner, M., additional, and Nyarangi-Dix, J.N., additional

Published
2020
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21. Pivotal trial of MRI-guided transurethral ultrasound ablation in men with localized prostate cancer: Two-year follow-up

Author

Klotz, L.H., primary, Chin, J., additional, Hatiboglu, G., additional, Koch, M., additional, Penson, D., additional, Pavlovich, C., additional, Raman, S., additional, Oto, A., additional, Fütterer, J., additional, Relle, J., additional, Lotan, Y., additional, Heidenreich, A., additional, Serrallach, M., additional, Haider, M., additional, Bonekamp, D., additional, Tirkes, T., additional, Arora, S., additional, Pantuck, A., additional, Zagaja, G., additional, Sedelaar, M., additional, Macura, K., additional, Costa, D., additional, Persigehl, T., additional, and Eggener, S., additional

Published
2020
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22. Five-year outcomes from a prospective phase I study of MRI-guided transurethral ultrasound ablation in men with localized prostate cancer

Author

Chin, J., primary, Hatiboglu, G., additional, Nair, S.M., additional, Relle, J., additional, Hafron, J., additional, Roethke, M.C., additional, Mueller-Wolf, M.B., additional, Bonekamp, D., additional, Kassam, Z., additional, Staruch, R., additional, Burtnyk, M., additional, Schlemmer, H., additional, and Pahernik, S., additional

Published
2020
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26. 3:45 PM Abstract No. 341 Pivotal study of magnetic resonance imaging–guided transurethral ultrasound ablation in men with localized prostate cancer: 12-month clinical and imaging outcomes

Author

Raman, S., primary, Futterer, J., additional, Oto, A., additional, Arora, S., additional, Tirkes, T., additional, Macura, K., additional, Bonekamp, D., additional, Haider, M., additional, Cool, D., additional, Nandalur, K., additional, Nicolau, C., additional, Costa, D., additional, Persigehl, T., additional, Purysko, A., additional, Staruch, R., additional, Burtnyk, M., additional, Chin, J., additional, Klotz, L., additional, and Eggener, S., additional

Published
2020
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27. Automated quantitative tumour response assessment of MRI in neuro-oncology with artificial neural networks: a multicentre, retrospective study

Author

Kickingereder, P., Isensee, F., Tursunova, I., Petersen, J. (Jørgen), Neuberger, U., Bonekamp, D., Brugnara, G., Schell, M., Kessler, T.A. (Torsten), Foltyn, M., Harting, I., Sahm, F., Prager, M., Nowosielski, M., Wick, W. (Wolfgang), Nolden, M., Radbruch, A., Debus, J., Schlemmer, H.P., Heiland, S., Platten, M. (Michael), Deimling, A. (Andreas) von, Bent, M.J. (Martin) van den, Gorlia, T.S. (Thierry), Bendszus, M, Maier-Hein, K.H., Kickingereder, P., Isensee, F., Tursunova, I., Petersen, J. (Jørgen), Neuberger, U., Bonekamp, D., Brugnara, G., Schell, M., Kessler, T.A. (Torsten), Foltyn, M., Harting, I., Sahm, F., Prager, M., Nowosielski, M., Wick, W. (Wolfgang), Nolden, M., Radbruch, A., Debus, J., Schlemmer, H.P., Heiland, S., Platten, M. (Michael), Deimling, A. (Andreas) von, Bent, M.J. (Martin) van den, Gorlia, T.S. (Thierry), Bendszus, M, and Maier-Hein, K.H.

Abstract

Background The Response Assessment in Neuro-Oncology (RANO) criteria and requirements for a uniform protocol have been introduced to standardise assessment of MRI scans in both clinical trials and clinical practice. However

Published
2019
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28. Automated quantitative tumour response assessment of MRI in neuro-oncology with artificial neural networks: a multicentre, retrospective study

Author

Kickingereder, P, Isensee, F, Tursunova, I, Petersen, J, Neuberger, U, Bonekamp, D, Brugnara, G, Schell, M, Kessler, T, Foltyn, M, Harting, I, Sahm, F, Prager, M, Nowosielski, M, Wick, A, Nolden, M, Radbruch, A, Debus, J, Schlemmer, HP, Heiland, S, Platten, M, von Deimling, A, van den Bent, Martin, Gorlia, T, Wick, W, Bendszus, M, Maier-Hein, KH, Kickingereder, P, Isensee, F, Tursunova, I, Petersen, J, Neuberger, U, Bonekamp, D, Brugnara, G, Schell, M, Kessler, T, Foltyn, M, Harting, I, Sahm, F, Prager, M, Nowosielski, M, Wick, A, Nolden, M, Radbruch, A, Debus, J, Schlemmer, HP, Heiland, S, Platten, M, von Deimling, A, van den Bent, Martin, Gorlia, T, Wick, W, Bendszus, M, and Maier-Hein, KH

Published
2019

30. Nutzen der präoperativen MRT und klinischer Parameter zur präzisen Vorhersage der Wahrscheinlichkeit einer wiedererlangten Kontinenz nach radikaler Prostatektomie

Author

Nyarangi-Dix, J, Wörner, J, Kopp-Schneider, A, Schütz, V, Bonekamp, D, Wiesenfarth, M, Stenzinger, A, Hadaschik, B, Hatiboglu, G, Dieffenbacher, S, Schlemmer, HP, Teber, D, Hohenfellner, M, and Radtke, JP

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Einleitung und Zielsetzung: Die Post-Prostatektomie-Inkontinenz hat einen signifikanten Einfluss auf die Lebensqualität des Patienten. Mit der Verbreitung der MRT der Prostata wurden ebenfalls Modelle, die klinische und MR-tomographische Parameter kombinieren, etabliert, um die Wahrscheinlichkeit[zum vollständigen Text gelangen Sie über die oben angegebene URL], 59. Jahrestagung der Südwestdeutschen Gesellschaft für Urologie e.V. - Urologie im Südwesten: Innovation aus Tradition

Published
2018
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31. Histopathologische Validierung der multiparametrischen MRT mittels Kombination aus extendierter systematischer Biopsie und MRT/TRUS-Fusionsbiopsie – eine Mapping-Studie an 316 Patienten

Author

Bonekamp, D, Schelb, P, Wiesenfarth, M, Kuder, TA, Deister, F, Hadaschik, B, Hohenfellner, M, Schlemmer, HP, and Radtke, JP

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Einleitung: Die MRT detektiert zuverlässig die Indexläsion des Prostatakarzinoms (PCa) innerhalb einer Prostata. SIe zeigt jedoch Schwächen im Nachweis multifokaler Tumoren und in der Darstellung der kompletten Tumorausdehnung klinisch signifikanter PCas. In der vorliegenden Arbeit wurden[zum vollständigen Text gelangen Sie über die oben angegebene URL], 59. Jahrestagung der Südwestdeutschen Gesellschaft für Urologie e.V. - Urologie im Südwesten: Innovation aus Tradition

Published
2018
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32. Magnetic resonance imaging-guided transurethral ultrasound ablation of prostate tissue in patients with localized prostate cancer: single-center evaluation of 6-month treatment safety and functional outcomes of intensified treatment parameters

Author

Hatiboglu, G., primary, Popeneciu, V., additional, Bonekamp, D., additional, Burtnyk, M., additional, Staruch, R., additional, Pahernik, S., additional, Tosev, G., additional, Radtke, J. P., additional, Motsch, J., additional, Schlemmer, H. P., additional, Hohenfellner, M., additional, and Nyarangi-Dix, J. N., additional

Published
2019
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33. Pivotal study of MRI-guided transurethral ultrasound ablation in men with localized prostate cancer: Preliminary results

Author

Klotz, L.H., primary, Hatiboglu, G., additional, Fütterer, J., additional, Persigehl, T., additional, Serrallach, M., additional, Koch, M., additional, Pavlovich, C., additional, Lotan, Y., additional, Raman, S., additional, Relle, J., additional, Zagaja, G., additional, Haider, M.A., additional, Arora, S.S., additional, Staruch, R.M., additional, Burtnyk, M.A., additional, Costa, D., additional, Oto, A., additional, Tirkes, T., additional, Sedelaar, J.P.M., additional, Bonekamp, D., additional, Heidenreich, A., additional, Penson, D., additional, Chin, J., additional, and Eggener, S., additional

Published
2019
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34. MRI-guided transurethral ultrasound ablation in patients with localized prostate cancer: 4-year outcomes of a prospective phase I trial

Author

Chin, J., primary, Hatiboglu, G., additional, Relle, J., additional, Dewar, M., additional, Hetou, K., additional, Kuru, T., additional, Popeneciu, I.V., additional, Hafron, J., additional, Roethke, M., additional, Mueller-Wolf, M., additional, Kassam, Z., additional, Staruch, R., additional, Burtnyk, M., additional, Bonekamp, D., additional, Schlemmer, H-P., additional, and Pahernik, S., additional

Published
2019
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35. Kombination aus multiparametrischer MRT und ERSPC Risikokalkulator: Entwicklung eines Nomogramms zur Prädiktion signifikanter Prostatakarzinome

Author

Radtke, J.P., Wiesenfarth, M., Kesch, C., Freitag, M., Alt, C., Roth, W., Wieczorek, K., Stock, C., Duensing, S., Roethke, M.C., Teber, D., Schlemmer, H.-P., Hohenfellner, M., Bonekamp, D., and Hadaschik, B.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Fragestellung: Die multiparametrische MRT (mpMRT) gewinnt zur Diagnostik von Prostatakarzinomen (PCa) zunehmend an Bedeutung und verbessert die Diagnose von signifikanten Prostatakarzinomen (SPCa) (Gleason-score ≥3+4). Zudem kann die Entscheidungsfindung zur Biopsie basierend auf European[zum vollständigen Text gelangen Sie über die oben angegebene URL], 63. Kongress der Nordrhein-Westfälischen Gesellschaft für Urologie

Published
2017

36. Kombination klinischer und MR-Parameter zur Vorhersage der seitenspezifischen extraprostatischen Tumorausdehnung vor Radikaler Prostatektomie

Author

Radtke, JP, Hadaschik, B, Bonekamp, D, Kesch, C, Hitthaler, B, Alt, C, Roth, W, Wieczorek, K, Duensing, S, Roethke, MC, Schlemmer, HP, Hohenfellner, M, and Teber, D

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Fragestellung: Die multiparametrische MRT (mpMRT) verbessert die Diagnostik signifikanter Prostatakarzinome (SPCa) und der extraprostatischen Tumorausdehnung (EPE). Wir kombinierten präoperative mpMRT-Daten und klinische Parameter zu einem Risikomodell (RM) um das individuelle seitenspezifische[zum vollständigen Text gelangen Sie über die oben angegebene URL], 63. Kongress der Nordrhein-Westfälischen Gesellschaft für Urologie

Published
2017
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37. Magnetic resonance imaging-guided transurethral ultrasound ablation of prostate tissue in patients with localized prostate cancer: single-center evaluation of 6-month treatment safety and functional outcomes of intensified treatment parameters.

Author

Hatiboglu, G., Popeneciu, V., Bonekamp, D., Burtnyk, M., Staruch, R., Pahernik, S., Tosev, G., Radtke, J. P., Motsch, J., Schlemmer, H. P., Hohenfellner, M., and Nyarangi-Dix, J. N.

Subjects
PROSTATE cancer patients, MAGNETIC resonance, CASTRATION-resistant prostate cancer, PROSTATE, TREATMENT effectiveness, PROSTATE cancer
Abstract

Objectives: To evaluate the effect of intensified treatment parameters on safety, functional outcomes, and PSA after MR-Guided Transurethral Ultrasound Ablation (TULSA) of prostatic tissue. Patients and methods: Baseline and 6-month follow-up data were collected for a single-center cohort of the multicenter Phase I (n = 14/30 at 3 sites) and Pivotal (n = 15/115 at 13 sites) trials of TULSA in men with localized prostate cancer. The Pivotal study used intensified treatment parameters (increased temperature and spatial extent of ablation coverage). The reporting site recruited the most patients to both trials, minimizing the influence of physician experience on this comparison of adverse events, urinary symptoms, continence, and erectile function between subgroups of both studies. Results: For Phase I and TACT patients, median age was 71.0 and 67.0 years, prostate volume 41.0 and 44.5 ml, and PSA 6.7 and 6.7 ng/ml, respectively. All 14 Phase I patients had low-risk prostate cancer, whereas 7 of 15 TACT patients had intermediate-risk disease. Baseline IIEF, IPSS, quality of life, and pad use were similar between groups. Pad use at 1 month and quality of life at 3 months favored Phase I patients. At 6 months, there were no significant differences in functional outcomes or adverse events. Conclusion: TULSA demonstrated acceptable clinical safety in Phase I trial. Intensified treatment parameters in the TACT Pivotal trial increased ablation coverage from 90 to 98% of the prostate without affecting 6-month adverse events or functional outcomes. Long-term follow-up and 12-month biopsies are needed to evaluate oncological safety. [ABSTRACT FROM AUTHOR]

Published
2020
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39. T1ρ-gewichtete dynamische Glukose-verstärkte Magnetresonanztomografie bei Glioblastompatienten

Author

Paech, D, additional, Schuenke, P, additional, Koehler, C, additional, Windschuh, J, additional, Mundiyanapurath, S, additional, Bickelhaupt, S, additional, Bonekamp, D, additional, Bäumer, P, additional, Bachert, P, additional, Ladd, M, additional, Bendszus, M, additional, Wick, W, additional, Unterberg, A, additional, Schlemmer, H, additional, Zaiss, M, additional, and Radbruch, A, additional

Published
2018
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40. Bi-institutioneller Vergleich manueller mit automatisch durch ein Adversarial Neural Network erstellten Prostatasegmentationen

Author

Bonekamp, D, additional, Penzkofer, T, additional, Kohl, S, additional, Baur, A, additional, Radtke, J, additional, Cash, H, additional, Götz, M, additional, Asbach, P, additional, Yaqubi, K, additional, Hitthaler, B, additional, Schelb, P, additional, Hadaschik, B, additional, Hohenfellner, M, additional, Schlemmer, H, additional, Hamm, B, additional, and Maier-Hein, K, additional

Published
2018
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41. Combined clinical parameters and multiparametric MRI for prediction of side-specific extraprostatic disease - a risk-model for patient-tailored risk stratification before radical prostatectomy

Author

Radtke, J.P., primary, Wiesenfarth, M., additional, Hadaschik, B., additional, Hitthaler, B., additional, Kesch, C., additional, Schütz, V., additional, Alt, C., additional, Roth, W., additional, Wieczorek, K., additional, Duensing, S., additional, Roethke, M.C., additional, Schlemmer, H.-P., additional, Hohenfellner, M., additional, Bonekamp, D., additional, and Teber, D., additional

Published
2018
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42. Preoperative magnetic resonance imaging and clinical parameters for accurate prediction of continence recovery following radical prostatectomy – membranous urethral length measurement on MRI outperform predictive models

Author

Nyarangi-Dix, J., primary, Wörner, J., additional, Kopp-Schneider, A., additional, Schütz, V., additional, Bonekamp, D., additional, Wiesenfarth, M., additional, Stenzinger, A., additional, Roth, W., additional, Hadaschik, B., additional, Schlemmer, H.P., additional, Hatiboglu, G., additional, Teber, D., additional, Hohenfellner, M., additional, and Radtke, J.P., additional

Published
2018
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43. MRI-guided transurethral ultrasound ablation in patients with localized prostate cancer: 3-year outcomes of a prospective phase I clinical trial

Author

Chin, J., primary, Relle, J., additional, Dewar, M., additional, Hetou, K., additional, Kuru, T., additional, Hatiboglu, G., additional, Popeneciu, I.V., additional, Hafron, J., additional, Roethke, M., additional, Mueller-Wolf, M., additional, Kassam, Z., additional, Staruch, R., additional, Burtnyk, M., additional, Bonekamp, D., additional, Schlemmer, H., additional, and Pahernik, S., additional

Published
2018
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44. Kombination aus multiparametrischer MRT und ERSPC Risikokalkulator: Entwicklung eines Nomogramms zur Prädiktion signifikanter Prostatakarzinome

Author

Radtke, JP, Wiesenfarth, M, Kesch, C, Freitag, M, Alt, C, Roth, W, Wieczorek, K, Stock, C, Duensing, S, Roethke, MC, Teber, D, Schlemmer, HP, Hohenfellner, M, Bonekamp, D, Hadaschik, B, Radtke, JP, Wiesenfarth, M, Kesch, C, Freitag, M, Alt, C, Roth, W, Wieczorek, K, Stock, C, Duensing, S, Roethke, MC, Teber, D, Schlemmer, HP, Hohenfellner, M, Bonekamp, D, and Hadaschik, B

Published
2017

45. Der Stellenwert der PSA-Dichte in Kombination mit PIRADS für die Tumorprädiktion des Prostatakarzinoms in der Prostatastanzbiopsie

Author

Distler, FA, Radtke, JP, Bonekamp, D, Kesch, C, Schlemmer, HP, Wieczorek, K, Hohenfellner, M, and Hadaschik, BA

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Die multiparametrische MRT (mpMRT) hat einen zunehmenden Stellenwert in der Prostatakarzinom(PC)-Diagnostik. Sie verbessert die PC-Detektion und kann theoretisch helfen, die Überdiagnose von insignifikanten PC durch weniger entnommene Stanzzylinder zu reduzieren. Unsere Hypothese ist[zum vollständigen Text gelangen Sie über die oben angegebene URL], 42. Gemeinsame Tagung der Bayerischen Urologenvereinigung und der Österreichischen Gesellschaft für Urologie und Andrologie

Published
2016
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46. Detektion von Indextumoren mit multiparametrischer MRT und MRT/TRUS-Fusionsbiopsie: Korrelationen mit 120 Prostatektomiepräparaten

Author

Radtke, J.P., Schwab, C., Wolf, M., Freitag, M., Alt, C.D., Kesch, C.V., Popeneciu, V., Huettenbrink, C., Gasch, C., Klein, T., Bonekamp, D., Duensing, S., Roth, W., Schueler, S., Stock, C., Schlemmer, H.-P., Roethke, M.C., Hohenfellner, M., and Hadaschik, B.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Fragestellung: Die multiparametrische MRT (mpMRI) und gezielte MRT/TRUS-Fusionsbiopsien (FGB) detektieren signifikante Prostatakarzinome (sPC) akkurater als konventionelle TRUS-Biopsien allein. Die Fragestellung der vorliegenden Arbeit war es, die Detektionsrate der mpMRT und FGB verglichen [zum vollständigen Text gelangen Sie über die oben angegebene URL], 62. Kongress der Nordrhein-Westfälischen Gesellschaft für Urologie

Published
2016

48. Kombination klinischer und MR-tomografischer Parameter zur Vorhersage signifikanter Prostatakarzinome und extrakapsulärer Tumorausdehnung

Author

Radtke, J, additional, Bonekamp, D, additional, Kesch, C, additional, Freitag, M, additional, Alt, C, additional, Celik, K, additional, Distler, F, additional, Roth, W, additional, Wieczorek, K, additional, Duensing, S, additional, Roethke, M, additional, Teber, D, additional, Schlemmer, H, additional, Hohenfellner, M, additional, and Hadaschik, B, additional

Published
2017
Full Text
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50. Combined clinical parameters and multiparametric MRI for advanced risk modeling of prostate cancer - patient-tailored risk stratification can reduce unnecessary biopsies

Author

Radtke, J.P., primary, Bonekamp, D., additional, Kesch, C., additional, Freitag, M., additional, Alt, C., additional, Celik, K., additional, Distler, F., additional, Roth, W., additional, Wieczorek, K., additional, Duensing, S., additional, Roethke, M., additional, Teber, D., additional, Schlemmer, H.-P., additional, Hohenfellner, M., additional, and Hadaschik, B., additional

Published
2017
Full Text
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