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19 results on '"Bonandrini, Barbara"'

1. Therapeutic potential of Mesenchymal Stem Cells for the treatment of diabetic peripheral neuropathy

Author

Monfrini, Marianna, Donzelli, Elisabetta, Rodriguez-Menendez, Virginia, Ballarini, Elisa, Carozzi, Valentina Alda, Chiorazzi, Alessia, Meregalli, Cristina, Canta, Annalisa, Oggioni, Norberto, Crippa, Luca, Avezza, Federica, Silvani, Sara, Bonandrini, Barbara, Figliuzzi, Marina, Remuzzi, Andrea, Porretta-Serapiglia, Carla, Bianchi, Roberto, Lauria, Giuseppe, Tredici, Giovanni, Cavaletti, Guido, and Scuteri, Arianna

Published
2017
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5. Bioengineering Organs for Blood Detoxification

Author

Legallais, Cécile, Kim, Dooli, Mihaila, Sylvia M, Mihajlovic, Milos, Figliuzzi, Marina, Bonandrini, Barbara, Salerno, Simona, Yousef Yengej, Fjodor A, Rookmaaker, Maarten B, Sanchez Romero, Natalia, Sainz-Arnal, Pilar, Pereira, Ulysse, Pasqua, Mattia, Gerritsen, Karin G F, Verhaar, Marianne C, Remuzzi, Andrea, Baptista, Pedro M, De Bartolo, Loredana, Masereeuw, Rosalinde, Stamatialis, Dimitrios, Afd Pharmacology, Pharmacology, Afd Pharmacology, Pharmacology, Biomécanique et Bioingénierie (BMBI), Université de Technologie de Compiègne (UTC)-Centre National de la Recherche Scientifique (CNRS), Cellules Biomatériaux Bioréacteurs (CBB), Université de Technologie de Compiègne (UTC)-Centre National de la Recherche Scientifique (CNRS)-Université de Technologie de Compiègne (UTC)-Centre National de la Recherche Scientifique (CNRS), Università della Calabria [Arcavacata di Rende] (Unical), departement of Pharmacology, Radboud University, Department of Pharmacology and Toxicology, Radboud University Medical Center [Nijmegen]-Radboud University Medical Center [Nijmegen], Department of Biomaterials Science and Technology [Maastricht, Netherlands], University of Twente [Netherlands]-MIRA Institute for Biomedical Technology and Technical Medicine [Maastricht, Netherlands], and Pharmaceutical and Pharmacological Sciences

Subjects
0301 basic medicine, kidneys, medicine.medical_specialty, bioengineered organs, Biomedical Engineering, UT-Hybrid-D, Pharmaceutical Science, Bioengineering, 02 engineering and technology, Bioinformatics, Artificial kidney, Kidney, Organ transplantation, law.invention, Biomaterials, 03 medical and health sciences, blood detoxification, livers, Animals, Humans, Liver, Liver, Artificial, Tissue Engineering, Bioartificial Organs, Tissue engineering, law, Detoxification, Medicine, biomaterials, biomedical Engineering, [SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/Biomaterials, membrane, ComputingMilieux_MISCELLANEOUS, Decellularization, business.industry, Bioartificial liver device, Settore ING-IND/35 - Ingegneria Economico-Gestionale, 021001 nanoscience & nanotechnology, 3. Good health, Transplantation, 030104 developmental biology, medicine.anatomical_structure, Artificial, 0210 nano-technology, business
Abstract

For patients with severe kidney or liver failure the best solution is currently organ transplantation. However, not all patients are eligible for transplantation and due to limited organ availability, most patients are currently treated with therapies using artificial kidney and artificial liver devices. These therapies, despite their relative success in preserving the patients' life, have important limitations since they can only replace part of the natural kidney or liver functions. As blood detoxification (and other functions) in these highly perfused organs is achieved by specialized cells, it seems relevant to review the approaches leading to bioengineered organs fulfilling most of the native organ functions. There, the culture of cells of specific phenotypes on adapted scaffolds that can be perfused takes place. In this review paper, first the functions of kidney and liver organs are briefly described. Then artificial kidney/liver devices, bioartificial kidney devices, and bioartificial liver devices are focused on, as well as biohybrid constructs obtained by decellularization and recellularization of animal organs. For all organs, a thorough overview of the literature is given and the perspectives for their application in the clinic are discussed.

Published
2018
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7. A novel hybrid silk-fibroin/polyurethane three-layered vascular graft: towards in situ tissue-engineered vascular accesses for haemodialysis

Author

van Uden, Sebastião, primary, Vanerio, Noemi, additional, Catto, Valentina, additional, Bonandrini, Barbara, additional, Tironi, Matteo, additional, Figliuzzi, Marina, additional, Remuzzi, Andrea, additional, Kock, Linda, additional, Redaelli, Alberto C L, additional, Greco, Francesco G, additional, and Riboldi, Stefania A, additional

Published
2019
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8. Bioengineering Organs for Blood Detoxification

Author

Afd Pharmacology, Pharmacology, Legallais, Cécile, Kim, Dooli, Mihaila, Sylvia M, Mihajlovic, Milos, Figliuzzi, Marina, Bonandrini, Barbara, Salerno, Simona, Yousef Yengej, Fjodor A, Rookmaaker, Maarten B, Sanchez Romero, Natalia, Sainz-Arnal, Pilar, Pereira, Ulysse, Pasqua, Mattia, Gerritsen, Karin G F, Verhaar, Marianne C, Remuzzi, Andrea, Baptista, Pedro M, De Bartolo, Loredana, Masereeuw, Rosalinde, Stamatialis, Dimitrios, Afd Pharmacology, Pharmacology, Legallais, Cécile, Kim, Dooli, Mihaila, Sylvia M, Mihajlovic, Milos, Figliuzzi, Marina, Bonandrini, Barbara, Salerno, Simona, Yousef Yengej, Fjodor A, Rookmaaker, Maarten B, Sanchez Romero, Natalia, Sainz-Arnal, Pilar, Pereira, Ulysse, Pasqua, Mattia, Gerritsen, Karin G F, Verhaar, Marianne C, Remuzzi, Andrea, Baptista, Pedro M, De Bartolo, Loredana, Masereeuw, Rosalinde, and Stamatialis, Dimitrios

Published
2018

13. Regression of Renal Disease by Angiotensin II Antagonism Is Caused by Regeneration of Kidney Vasculature

Author

Remuzzi, Andrea, primary, Sangalli, Fabio, additional, Macconi, Daniela, additional, Tomasoni, Susanna, additional, Cattaneo, Irene, additional, Rizzo, Paola, additional, Bonandrini, Barbara, additional, Bresciani, Elena, additional, Longaretti, Lorena, additional, Gagliardini, Elena, additional, Conti, Sara, additional, Benigni, Ariela, additional, and Remuzzi, Giuseppe, additional

Published
2016
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14. Effect of inborn pancreatic islet deficit

Author

Remuzzi, Andrea, Remuzzi, Giuseppe, Cattaneo, Irene, Bonandrini, Barbara, and Figliuzzi, Marina

Subjects
Settore ING-IND/34 - Bioingegneria Industriale
Published
2010

16. Recellularization of Well-Preserved Acellular Kidney Scaffold Using Embryonic Stem Cells

Author

Bonandrini, Barbara, primary, Figliuzzi, Marina, additional, Papadimou, Evangelia, additional, Morigi, Marina, additional, Perico, Norberto, additional, Casiraghi, Federica, additional, Dipl, Chemistry, additional, Sangalli, Fabio, additional, Conti, Sara, additional, Benigni, Ariela, additional, Remuzzi, Andrea, additional, and Remuzzi, Giuseppe, additional

Published
2014
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19. Mesenchymal stem cells help pancreatic islet transplantation to control type 1 diabetes.

Author

Figliuzzi M, Bonandrini B, Silvani S, and Remuzzi A

Abstract

Islet cell transplantation has therapeutic potential to treat type 1 diabetes, which is characterized by autoimmune destruction of insulin-producing pancreatic islet β cells. It represents a minimal invasive approach for β cell replacement, but long-term blood control is still largely unachievable. This phenomenon can be attributed to the lack of islet vasculature and hypoxic environment in the immediate post-transplantation period that contributes to the acute loss of islets by ischemia. Moreover, graft failures continue to occur because of immunological rejection, despite the use of potent immunosuppressive agents. Mesenchymal stem cells (MSCs) have the potential to enhance islet transplantation by suppressing inflammatory damage and immune mediated rejection. In this review we discuss the impact of MSCs on islet transplantation and focus on the potential role of MSCs in protecting islet grafts from early graft failure and from autoimmune attack.

Published
2014
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