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193 results on '"Bommert, Kurt"'

1. 7-Dehydrocholesterol is an endogenous suppressor of ferroptosis

Author

Freitas, Florencio Porto, Alborzinia, Hamed, dos Santos, Ancély Ferreira, Nepachalovich, Palina, Pedrera, Lohans, Zilka, Omkar, Inague, Alex, Klein, Corinna, Aroua, Nesrine, Kaushal, Kamini, Kast, Bettina, Lorenz, Svenja M., Kunz, Viktoria, Nehring, Helene, Xavier da Silva, Thamara N., Chen, Zhiyi, Atici, Sena, Doll, Sebastian G., Schaefer, Emily L., Ekpo, Ifedapo, Schmitz, Werner, Horling, Aline, Imming, Peter, Miyamoto, Sayuri, Wehman, Ann M., Genaro-Mattos, Thiago C., Mirnics, Karoly, Kumar, Lokender, Klein-Seetharaman, Judith, Meierjohann, Svenja, Weigand, Isabel, Kroiss, Matthias, Bornkamm, Georg W., Gomes, Fernando, Netto, Luis Eduardo Soares, Sathian, Manjima B., Konrad, David B., Covey, Douglas F., Michalke, Bernhard, Bommert, Kurt, Bargou, Ralf C., Garcia-Saez, Ana, Pratt, Derek A., Fedorova, Maria, Trumpp, Andreas, Conrad, Marcus, and Friedmann Angeli, José Pedro

Published
2024
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3. IL-10 mediates plasmacytosis-associated immunodeficiency by inhibiting complement-mediated neutrophil migration

Author

Kulkarni, Upasana, Karsten, Christian M., Kohler, Thomas, Hammerschmidt, Sven, Bommert, Kurt, Tiburzy, Benjamin, Meng, Lingzhang, Thieme, Lara, Recke, Andreas, Ludwig, Ralf J., Pollok, Karolin, Kalies, Kathrin, Bogen, Bjarne, Boettcher, Martin, Kamradt, Thomas, Hauser, Anja E., Langer, Christian, Huber-Lang, Markus, Finkelman, Fred D., Köhl, Jörg, Wong, David M., and Manz, Rudolf Armin

Published
2016
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4. Proteins Implicated in Neurotransmitter Release and Reuptake

Author

Betz, Heinrich, O’Connor, Vincent, Dresbach, Thomas, Pellegrini, Lorenzo, Bommert, Kurt, DeBello, William, Hunt, James M., Schweizer, Felix, Augustine, George, Charlton, Milton P., Adams, Ralph, Sato, Kohji, Püschel, Andreas W., Sur, Cyrille, Schloss, Patrick, and Pöğün, Şakire, editor

Published
1997
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5. 7-Dehydrocholesterol is an endogenous suppressor of ferroptosis

Author

Angeli, Jose Pedro Friedmann, primary, Freitas, Florencio Porto, additional, Nepachalovich, Palina, additional, Puentes, Lohans, additional, Zilka, Omkar, additional, Inague, Alex, additional, Lorenz, Svenja, additional, Kunz, Viktoria, additional, Nehring, Helene, additional, Silva, Thamara Nishida Xavier da, additional, Chen, Zhiyi, additional, Doll, Sebastian, additional, Schmitz, Werner, additional, Imming, Peter, additional, Miyamoto, Sayuri, additional, Klein-Seetharaman, Judith, additional, Kumar, Lokender, additional, Genaro-Mattos, Thiago Cardoso, additional, Mirnics, Karoly, additional, Meierjohann, Svenja, additional, Kroiss, Matthias, additional, Weigand, Isabel, additional, Bommert, Kurt, additional, Bargou, Ralf, additional, Garcia-Saez, Ana, additional, Pratt, Derek, additional, Fedorova, Maria, additional, Wehmann, Ann, additional, Horling, Aline, additional, Bornkamm, Georg, additional, and Conrad, Marcus, additional

Published
2021
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26. Inhibition of neurotransmitter release by C2 domain peptides implicates synaptotagmin in exocytosis

Author

Bommert, Kurt, Charlton, Milton P., DeBello, William L., Chin, Gilbert J., Betz, Heinrich, and Augustine, George J.

Subjects
Neurotransmitters -- Research, Exocytosis -- Research, Neural transmission -- Regulation, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

The inhibition of neurotransmitter release by C2-domain peptides indicate the role of synaptotagmin in regulating the process of exocytosis. This was shown by injecting the said peptides into the presynaptic terminals of the giant squid Loligo pealei. The peptides competed in blocking the release of neurotransmitters, suggesting the role of Ca2+ in the reverse process. Ca+2 initiates the process by regulating the interaction of synaptotagmin with an acceptor protein.

Published
1993

28. Differential expression of Na+/K+-ATPase α-subunits in mouse hippocampal interneurones and pyramidal cells

Author

Richards, Kathryn S, Bommert, Kurt, Szabo, Gabor, and Miles, Richard

Subjects
Male, Glutamate Decarboxylase, Pyramidal Cells, Green Fluorescent Proteins, food and beverages, Gene Expression, Mice, Transgenic, Hippocampus, Immunohistochemistry, Membrane Potentials, Mice, Inbred C57BL, Mice, nervous system, Interneurons, Synapses, Animals, Female, Enzyme Inhibitors, Sodium-Potassium-Exchanging ATPase, Ouabain, In Situ Hybridization, Neuroscience
Abstract

The sodium pump (Na+/K+-ATPase), maintains intracellular and extracellular concentrations of sodium and potassium by catalysing ATP. Three sodium pump alpha subunits, ATP1A1, ATP1A2 and ATP1A3, are expressed in brain. We compared their role in pyramidal cells and a subset of interneurones in the subiculum. Interneurones were identified by their expression of GFP under the GAD-65 promoter. We used the sensitivity to the cardiac glycoside, ouabain, to discriminate between different alpha subunit isoforms. GFP-positive interneurones were depolarized by nanomolar doses of ouabain, but higher concentrations were needed to depolarize pyramidal cells. Comparison of pump currents in these cells revealed a current sensitive to low doses of ouabain in interneurones, while micromolar doses of ouabain were needed to suppress the pump current in subicular pyramidal cells. As predicted, nanomolar doses of ouabain increased the frequency but not the amplitudes of IPSPs in pyramidal cells. Immunostaining confirmed a differential distribution of alpha-subunits of the Na+/K+-ATPase in subicular interneurones and pyramidal cells. In conclusion, these data suggest that while ATP1A3-isoforms regulate sodium and potassium homeostasis in subicular interneurones, ATP1A1-isoforms assume this function in pyramidal cells. This differential expression of sodium pump isoforms may contribute to differences in resting membrane potential of subicular interneurones and pyramidal cells.

Published
2007

29. Eosinophils and Megakaryocytes Support the Early Growth of Murine MOPC315 Myeloma Cells in Their Bone Marrow Niches

Author

Wong, David, primary, Winter, Oliver, additional, Hartig, Christina, additional, Siebels, Svenja, additional, Szyska, Martin, additional, Tiburzy, Benjamin, additional, Meng, Lingzhang, additional, Kulkarni, Upasana, additional, Fähnrich, Anke, additional, Bommert, Kurt, additional, Bargou, Ralf, additional, Berek, Claudia, additional, Chu, Van Trung, additional, Bogen, Bjarne, additional, Jundt, Franziska, additional, and Manz, Rudolf Armin, additional

Published
2014
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30. A Novel Mouse Model for Multiple Myeloma (MOPC315.BM) That Allows Noninvasive Spatiotemporal Detection of Osteolytic Disease

Author

Hofgaard, Peter O., primary, Jodal, Henriette C., additional, Bommert, Kurt, additional, Huard, Bertrand, additional, Caers, Jo, additional, Carlsen, Harald, additional, Schwarzer, Rolf, additional, Schünemann, Nicole, additional, Jundt, Franziska, additional, Lindeberg, Mona M., additional, and Bogen, Bjarne, additional

Published
2012
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37. STAT3 and MAPK signaling maintain overexpression of heat shock proteins 90α and β in multiple myeloma cells, which critically contribute to tumor-cell survival

Author

Chatterjee, Manik, primary, Jain, Sarika, additional, Stühmer, Thorsten, additional, Andrulis, Mindaugas, additional, Ungethüm, Ute, additional, Kuban, Ralf-Jürgen, additional, Lorentz, Heike, additional, Bommert, Kurt, additional, Topp, Max, additional, Krämer, Doris, additional, Müller-Hermelink, Hans Konrad, additional, Einsele, Hermann, additional, Greiner, Axel, additional, and Bargou, Ralf C., additional

Published
2006
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38. Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma

Author

Mathas, Stephan, primary, Janz, Martin, additional, Hummel, Franziska, additional, Hummel, Michael, additional, Wollert-Wulf, Brigitte, additional, Lusatis, Simone, additional, Anagnostopoulos, Ioannis, additional, Lietz, Andreas, additional, Sigvardsson, Mikael, additional, Jundt, Franziska, additional, Jöhrens, Korinna, additional, Bommert, Kurt, additional, Stein, Harald, additional, and Dörken, Bernd, additional

Published
2005
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41. c-FLIP Mediates Resistance of Hodgkin/Reed-Sternberg Cells to Death Receptor–induced Apoptosis

Author

Mathas, Stephan, primary, Lietz, Andreas, additional, Anagnostopoulos, Ioannis, additional, Hummel, Franziska, additional, Wiesner, Burkhard, additional, Janz, Martin, additional, Jundt, Franziska, additional, Hirsch, Burkhard, additional, Jöhrens-Leder, Korinna, additional, Vornlocher, Hans-Peter, additional, Bommert, Kurt, additional, Stein, Harald, additional, and Dörken, Bernd, additional

Published
2004
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