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In the present study, FeSiBP and FeCoSiBP ribbons with a fully amorphous structure were made by melt spinning technique. A detailed analysis of the isochronal crystallization behavior is presented in this paper. The influence of cobalt on the crystallization kinetics of the alloys was studied under isochronal conditions using differential scanning calorimetry (DSC). Apparent and local activation energy values were determined by Kissinger, Ozawa and Kissinger-Akahira-Sunose (KAS) methods. The results indicate that appropriate amounts of cobalt can significantly enhance the thermal stability of Fe-based alloys, through an increase in nucleation activation energy from 538kJ/mol to 701kJ/mol, obtained by Kissinger method. Furthermore, with the method proposed by Matusita, it was possible to obtain global values for the Avrami exponent, noting that from a general perspective, Co changes the mechanism from diffusion controlled to interface controlled. This leads to the conclusion that the crystallization process is complex and takes place in more than one stage. Therefore, the determination of nucleation mechanisms and dimensional growth is difficult due to the inapplicability of the Johnson-Melh-Avrami (JMA) model. As such, a study under isothermal conditions is suggested, in order to achieve a full understanding of the mechanisms involved. RESUMEN En el presente estudio, se obtuvieron cintas de las aleaciones FeSiBP y FeCoSiBP con una estructura completamente amorfa mediante la técnica de “melt spinning”; en este artículo se presenta un análisis detallado del comportamiento de las aleaciones bajo cristalización isócrona La influencia del cobalto en la cinética de cristalización de las aleaciones se estudió bajo condiciones isócronas utilizando calorimetría diferencial de barrido (DSC por su sigla en inglés). Los valores de energía de activación local y aparente se determinaron mediante los métodos de Kissinger, Ozawa y Kissinger-Akahira-Sunose (KAS). Estos resultados indican que cantidades apropiadas de cobalto pueden mejorar significativamente la estabilidad térmica de las aleaciones base Fe a través de un aumento en la energía de activación de nucleación, pasando de 538 kJ/mol a 701kJ/mol, con el modelo de Kissinger. Además, con el método propuesto por Matusita, fue posible obtener valores globales para el exponente de Avrami, observando que, desde una perspectiva general, el Co cambia el mecanismo de crecimiento de controlado por difusión a uno controlado por interfaz, afirmando la complejidad del proceso de cristalización, que tiene lugar en más de una etapa. Por otro lado, la determinación de los mecanismos de nucleación y la dimensionalidad del crecimiento es difícil debido a la inaplicabilidad del modelo Johnson-Melh-Avrami (JMA), por lo que se sugiere un estudio en condiciones isotérmicas, con el fin de lograr un mayor entendimiento de los mecanismos implicados.

Leaf explants from in vitro plantlets of sweetpotato Ipomoea batatas (L.) cv. Regal were used to obtain transgenic plants. Explants were inoculated with a strain LBA 4404 of Agrobacterium tumefaciens which contains a binary vector pBI121 harboring neomicyn phosphotransferase (NPT-II) and β-glucuronidase (GUS) genes. Two procedures were used for obtaining regenerated transgenic plants ; 1) whole explants or 2 ) roots originated from the leaf explants. Regenerated shoots obtained in a selective medium containing 100 mg/ 1 kanamycin, were assayed for kanamycin resistance, GUS histochemical assay and Southern blot analysis. GUS histochemical assays on roots revealed GUS expression in all plants regenerated and rooted on a selection medium containing 100 mg/1 kanamycin. （和文） 組織培養由来の葉片外植体を用いて、サツマイモ品種Regalの形質転換を行った。使用したベクターはNPT-II遺伝子およびβ-glucuronidase(GUS)遺伝子を組み込んだバイナリーベクターのpBI121であった。これをのAgrobacterium tumefaciensのLBA4404に取り込み、形質転換を 1) 葉片外植体および 2 )葉片外植体起原の根の2種の材料/方法で試した。再分化した植物体については、100ppmカナマイシンを含む培地で選抜を行った。ついで、GUSによる選抜およびGUS遺伝子をプローブとしたサザン検定を行った。カナマイシン培地での選抜およびGUSによる評価を総合すると、組み換え体サツマイモ植物が育成されたことが確認された。, 継続後誌:近畿大学先端技術総合研究所紀要 = Memoirs of Institute of Advanced Technology, Kinki University

The presence of anemia and renal dysfunction grants a bad prognosis for patients with heart failure and reduced ejection fraction (HFREF). The impact on patients with heart failure and normal ejection fraction (HFNEF) is not widely studied.To study the prevalence and the prognosis of anemia and renal dysfunction (RD) in patients with heart failure according to the type of ventricular dysfunction.A total of 209 patients with chronic and stable heart failure were prospectively studied. Individuals with ejection fraction50% were considered as HFREF patients. Anemia was defined, based on WHO criteria, as hemoglobin13 g/dl for men and12 g/dl for women. Renal function was calculated by means of the Simplified Modified Diet Renal Disease (sMDRD) formula. Hospitalizations, emergency admittances and obit by cardiac causes were considered as cardiac events.Ninety patients had HFREF and 119 had HFNEF. The glomerular filtration rate (GFR) was smaller in HFREF group (57.6 +/- 66.2 versus 94.8 +/- 36.6 ml/min/1.73m(2); p=0.01). There was no difference in the prevalence of anemia between groups (23.3% versus 18.5%; p=0.34). Moderate to severe RD prevalence was higher in HFREF group (32.2% versus 16.8%; p=0.01). RD was the only factor associated with anemia that was independently associated with cardiac events (HR 2.52; 95%CI=1.27-5.2; p=0.01).RD was less prevalent in HFNEF, while the prevalence of anemia did not differ between groups. RD was predictor of cardiac events independently on ejection fraction.