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13 results on '"Bolivar, Gema"'

8. Cornea and Glaucoma

Author

Bolivar, Gema

Subjects
Medical / Ophthalmology
Abstract

Cornea and Glaucoma

Published
2013

9. Orbscan Topography in Primary Open-Angle Glaucoma

Author

Universidad de Alicante. Departamento de Óptica, Farmacología y Anatomía, Arranz-Marquez, Esther, Bolivar, Gema, Piñero, David P., Konstas, Anastasios G.P., Mikropoulos, Dimitrios G., Teus, Miguel A., Universidad de Alicante. Departamento de Óptica, Farmacología y Anatomía, Arranz-Marquez, Esther, Bolivar, Gema, Piñero, David P., Konstas, Anastasios G.P., Mikropoulos, Dimitrios G., and Teus, Miguel A.

Abstract

Purpose: To compare anterior and posterior corneal curvatures between eyes with primary open-angle glaucoma (POAG) and healthy eyes. Methods: This is a prospective, cross-sectional, observer-masked study. A total of 138 white subjects (one eye per patient) were consecutively recruited; 69 eyes had POAG (study group), and the other 69 comprised a group of healthy control eyes matched for age and central corneal pachymetry with the study ones. Exclusion criteria included any corneal or ocular inflammatory disease, previous ocular surgery, or treatment with carbonic anhydrase inhibitors. The same masked observer performed Goldmann applanation tonometry, ultrasound pachymetry, and Orbscan II topography in all cases. Central corneal thickness, intraocular pressure, and anterior and posterior topographic elevation maps were analyzed and compared between both groups. Results: Patients with POAG had greater forward shifting of the posterior corneal surface than that in healthy control eyes (p < 0.01). Significant differences in anterior corneal elevation between controls and POAG eyes were also found (p < 0.01). Conclusions: Primary open-angle glaucoma eyes have a higher elevation of the posterior corneal surface than that in central corneal thickness–matched nonglaucomatous eyes.

Published
2013

13. Short-term effects of latanoprost on anterior chamber depth in patients with glaucoma or ocular hypertension.

Author

Gutiérrez-Ortiz C, Teus MA, and Bolivar G

Subjects
Adult, Aged, Aged, 80 and over, Anterior Chamber diagnostic imaging, Female, Humans, Latanoprost, Male, Middle Aged, Miotics administration & dosage, Ocular Hypertension drug therapy, Ophthalmic Solutions administration & dosage, Pilocarpine administration & dosage, Prospective Studies, Ultrasonography, Visual Acuity drug effects, Anterior Chamber drug effects, Antihypertensive Agents administration & dosage, Glaucoma, Open-Angle drug therapy, Prostaglandins F, Synthetic administration & dosage
Abstract

Purpose: Prostaglandin F(2alpha) analogues, such as latanoprost, may cause a decrease in the extracellular matrices, such as collagen, and changes in fibrillin-1; both are components of the ciliary zonules. However, the mechanical effect of these changes on the dynamics of the ciliary zonules is unknown. This study was conducted to evaluate the effect of latanoprost 0.005% on anterior chamber depth (ACD), best corrected visual acuity (BCVA), lens thickness, and anterior chamber dynamics in patients with glaucoma or ocular hypertension., Methods: This was a prospective, nonrandomized, autocomparative trial that included 40 patients (40 eyes) with glaucoma or ocular hypertension. ACD was measured with ultrasonography before and after 1 month of treatment with latanoprost. In addition, ACD was measured before and 1 hour after instillation of pilocarpine 2% at baseline and 1 month after treatment with latanoprost. To assess the reproducibility of the ultrasonic measurements, a control group of 20 patients (20 eyes) who did not receive latanoprost was also analyzed., Results: The mean ACD before treatment with latanoprost and before the instillation of pilocarpine was 3.14 +/- 0.46 mm (SD) and after the instillation of pilocarpine, 3.04 +/- 0.46 mm (SD). After 1 month of treatment with latanoprost, ACD was 2.98 +/- 0.44 mm (SD) before instillation of pilocarpine and 2.91 +/-0.49 mm (SD) after instillation of pilocarpine. P < or = 0.05 was reached for all comparisons., Conclusions: These findings suggest that latanoprost decreases ACD in patients with glaucoma or ocular hypertension after 1 month of treatment.

Published
2006
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