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10 results on '"Boldsen, Jens K"'

1. Cohort Profile:The Danish Blood Donor Study

Author

Erikstrup, Christian, Sørensen, Erik, Nielsen, Kaspar R, Bruun, Mie T, Petersen, Mikkel S, Rostgaard, Klaus, Thørner, Lise W, Larsen, Margit, Mikkelsen, Susan, Dinh, Khoa M, Schwinn, Michael, Rigas, Andreas S, Didriksen, Maria, Dowsett, Joseph, von Stemann, Jakob H, Brodersen, Thorsten, Paulsen, Isabella W, Hindhede, Lotte, Sækmose, Susanne G, Kaspersen, Kathrine A, Boldsen, Jens K, Kjerulff, Bertram, Werge, Thomas, Brunak, Søren, Banasik, Karina, Hansen, Thomas F, Ullum, Henrik, Hjalgrim, Henrik, Ostrowski, Sisse R, Pedersen, Ole B, Erikstrup, Christian, Sørensen, Erik, Nielsen, Kaspar R, Bruun, Mie T, Petersen, Mikkel S, Rostgaard, Klaus, Thørner, Lise W, Larsen, Margit, Mikkelsen, Susan, Dinh, Khoa M, Schwinn, Michael, Rigas, Andreas S, Didriksen, Maria, Dowsett, Joseph, von Stemann, Jakob H, Brodersen, Thorsten, Paulsen, Isabella W, Hindhede, Lotte, Sækmose, Susanne G, Kaspersen, Kathrine A, Boldsen, Jens K, Kjerulff, Bertram, Werge, Thomas, Brunak, Søren, Banasik, Karina, Hansen, Thomas F, Ullum, Henrik, Hjalgrim, Henrik, Ostrowski, Sisse R, and Pedersen, Ole B

Published
2023

3. Transit time homogenization in ischemic stroke – A novel biomarker of penumbral microvascular failure?

Author

Engedal, Thorbjørn S, Hjort, Niels, Hougaard, Kristina D, Simonsen, Claus Z, Andersen, Grethe, Mikkelsen, Irene Klærke, Boldsen, Jens K, Eskildsen, Simon F, Hansen, Mikkel B, Angleys, Hugo, Jespersen, Sune N, Pedraza, Salvador, Cho, Tae H, Serena, Joaquín, Siemonsen, Susanne, Thomalla, Götz, Nighoghossian, Norbert, Fiehler, Jens, Mouridsen, Kim, and Østergaard, Leif

Published
2018
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4. Cohort Profile: The Danish Blood Donor Study

Author

Erikstrup, Christian, primary, Sørensen, Erik, additional, Nielsen, Kaspar R, additional, Bruun, Mie T, additional, Petersen, Mikkel S, additional, Rostgaard, Klaus, additional, Thørner, Lise W, additional, Larsen, Margit, additional, Mikkelsen, Susan, additional, Dinh, Khoa M, additional, Schwinn, Michael, additional, Rigas, Andreas S, additional, Didriksen, Maria, additional, Dowsett, Joseph, additional, von Stemann, Jakob H, additional, Brodersen, Thorsten, additional, Paulsen, Isabella W, additional, Hindhede, Lotte, additional, Sækmose, Susanne G, additional, Kaspersen, Kathrine A, additional, Boldsen, Jens K, additional, Kjerulff, Bertram, additional, Werge, Thomas, additional, Brunak, Søren, additional, Banasik, Karina, additional, Hansen, Thomas F, additional, Ullum, Henrik, additional, Hjalgrim, Henrik, additional, Ostrowski, Sisse R, additional, and Pedersen, Ole B, additional

Published
2022
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7. Transit time homogenization in ischemic stroke – A novel biomarker of penumbral microvascular failure?

Author

Engedal, Thorbjørn S, primary, Hjort, Niels, additional, Hougaard, Kristina D, additional, Simonsen, Claus Z, additional, Andersen, Grethe, additional, Mikkelsen, Irene Klærke, additional, Boldsen, Jens K, additional, Eskildsen, Simon F, additional, Hansen, Mikkel B, additional, Angleys, Hugo, additional, Jespersen, Sune N, additional, Pedraza, Salvador, additional, Cho, Tae H, additional, Serena, Joaquín, additional, Siemonsen, Susanne, additional, Thomalla, Götz, additional, Nighoghossian, Norbert, additional, Fiehler, Jens, additional, Mouridsen, Kim, additional, and Østergaard, Leif, additional

Published
2017
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9. Spatial distribution of malignant tissue in gliomas: correlations of 11C-L-methionine positron emission tomography and perfusion- and diffusion-weighted magnetic resonance imaging.

Author

Tietze, Anna, Boldsen, Jens K., Mouridsen, Kim, Ribe, Lars, Dyve, Suzan, Cortnum, Søren, Østergaard, Leif, and Borghammer, Per

Subjects
*TISSUES, *GLIOMAS, *PHYSIOLOGICAL effects of methionine, *POSITRON emission tomography, *DIFFUSION magnetic resonance imaging, *DIAGNOSIS, *CANCER
Abstract

Background: The prognosis of glioma patients is contingent on precise target selection for stereotactic biopsies and the extent of tumor resection. 11C-L-methionine (MET) positron emission tomography (PET) demonstrates tumor heterogeneity and invasion with high diagnostic accuracy. Purpose: To compare the spatial tumor distribution delineated by MET PET with that by perfusion- and diffusion-weighted magnetic resonance imaging (MRI), in order to understand the diagnostic value of these MRI methods, when PET is not available. Material and Methods: Presurgical MET PET and MRI, including perfusion- and diffusion-weighted MRI, were acquired in 13 patients (7 high-grade gliomas, 6 low-grade gliomas). A quantitative volume of interest analysis was performed to compare the modalities objectively, supplemented by a qualitative evaluation that assessed the clinical applicability. Results: The inaccuracy of conventional MRI was confirmed (area under the curve for predicting voxels with high MET uptake = 0.657), whereas cerebral blood volume (CBV) maps calculated from perfusion data improved accuracy (area under the curve = 0.760). We considered CBV maps diagnostically comparable to MET PET in 5/7 cases of high-grade gliomas, but insufficient in all cases of low-grade gliomas when evaluated subjectively. Cerebral blood flow and apparent diffusion coefficient maps did not contribute to further accuracy. Conclusion: Adding perfusion-weighted MRI to the presurgical protocol can increase the diagnostic accuracy of conventional MRI and is a simple and well-established method compared to MET PET. However, the definition of low-grade gliomas with subtle or no alterations on cerebral blood volume maps remains a diagnostic challenge for stand-alone MRI. [ABSTRACT FROM AUTHOR]

Published
2015
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10. Cohort Profile: The Danish Blood Donor Study.

Author

Erikstrup C, Sørensen E, Nielsen KR, Bruun MT, Petersen MS, Rostgaard K, Thørner LW, Larsen M, Mikkelsen S, Dinh KM, Schwinn M, Rigas AS, Didriksen M, Dowsett J, von Stemann JH, Brodersen T, Paulsen IW, Hindhede L, Sækmose SG, Kaspersen KA, Boldsen JK, Kjerulff B, Werge T, Brunak S, Banasik K, Hansen TF, Ullum H, Hjalgrim H, Ostrowski SR, and Pedersen OB

Subjects
Humans, Denmark epidemiology, Blood Donors
Published
2023
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