394 results on '"Boj, Sylvia"'
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2. Repeatability and reproducibility of the Forskolin-induced swelling (FIS) assay on intestinal organoids from people with Cystic Fibrosis
3. Centralized intestinal organoid generation is a feasible and safe approach for personalized medicine as demonstrated in the HIT-CF Europe Organoid Study
4. Intestinal organoids as an in vitro platform to characterize disposition, metabolism, and safety profile of small molecules
5. Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo
6. Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer
7. Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors
8. Lumacaftor/ivacaftor in people with cystic fibrosis with an A455E–CFTR mutation
9. Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids
10. Targeting G542X CFTR nonsense alleles with ELX-02 restores CFTR function in human-derived intestinal organoids
11. Patient-derived pancreatic tumour organoids identify therapeutic responses to oncolytic adenoviruses
12. CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank
13. Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling
14. Long-term culture, genetic manipulation and xenotransplantation of human normal and breast cancer organoids
15. Pancreatic cancer organoids recapitulate disease and allow personalized drug screening
16. Model organoids provide new research opportunities for ductal pancreatic cancer
17. Preclinical models of pancreatic ductal adenocarcinoma
18. Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response
19. Repeatability and reproducibility of the Forskolin-induced swelling (FIS) assay on intestinal organoids from people with Cystic Fibrosis
20. Patient-derived organoids as a predictive biomarker for treatment response in cancer patients
21. Organoid models of human and mouse ductal pancreatic cancer.
22. Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response
23. Cystic fibrosis: Beyond the airways. Report on the meeting of the basic science working group in Loutraki, Greece
24. Expansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation Potential
25. Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids
26. A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity
27. RNF43 truncations trap CK1 to drive niche‐independent self‐renewal in cancer
28. A Transcription Factor Regulatory Circuit in Differentiated Pancreatic Cells
29. Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer
30. Molecular and Functional Characterization of Human Intestinal Organoids and Monolayers for Modeling Epithelial Barrier
31. Abstract 157: Patient in the lab: Down-scaling patient-derived organoid screening for diagnostic purposes
32. Abstract 908: Tumour organoid-t cell co-culture assay to evaluate CAR t cell cytotoxicity
33. Abstract 151: Optimization of screening conditions using patient-derived organoids for diagnostic purposes
34. Abstract 5917: Development of a medium-to-high throughput organoid-bacteria co-culture platform for the assessment of host pathogen interaction
35. Abstract 189: Developing a patient-derived organoid biobank, suitable for large scale drug screenings
36. Abstract 188: Autologous organoids and T cell co-cultures as a powerful personalized platform for immunotherapy development
37. Abstract 2924: Organoid co-cultures with autologous T cells to assess toxicity and efficacy of bispecific antibodies
38. Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice
39. Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors
40. Long‐term expanding human airway organoids for disease modeling
41. Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation
42. Molecular and Functional Characterization of Human Intestinal Organoids and Monolayers for Modeling Epithelial Barrier
43. Engineering multicellular living systems—a Keystone Symposia report
44. Diabetes Risk Gene and Wnt Effector Tcf7l2/TCF4 Controls Hepatic Response to Perinatal and Adult Metabolic Demand
45. Abstract 4112: Patient derived organoids predict clinical response: A patient in the lab
46. Abstract 1416: Aurora kinase is synthetic lethal with APC loss of function in engineered human colon organoid models
47. Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice
48. Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice
49. Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR x LGR5 bispecific antibody with efficacy in epithelial tumors
50. Molecular and Functional Characterization of Human Intestinal Organoids and Monolayers for Modeling Epithelial Barrier.
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