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1. A retrospective study on cholera understanding and WASH (water, sanitation, and hygiene) behavior among adolescents in three regions of La Gonâve, Haiti

Author

Yuna Kim, Bohye Shin, Seoung Eun Kim, Bernard Cajuste, and Jeoung A. Kwon

Subjects
Cholera Outbreak, Water, Sanitation, and Hygiene (WASH), Adolescents, Haiti, La Gonâve, Infectious and parasitic diseases, RC109-216, Public aspects of medicine, RA1-1270
Abstract

Backgrounds: This study assesses the impact of Water, Sanitation, and Hygiene (WASH) interventions on cholera understanding and hygiene practices in La Gonâve Island, Haiti. It examines the changes after implementing interventions in seven villages across the Downtown, Mountain, and Seaside regions. Methods: A retrospective investigation surveyed 210 school students from each region using a validated questionnaire. It assessed knowledge, attitudes, practices (KAP), and environmental aspects related to cholera and hygiene. Data analysis involved descriptive statistics and chi-square tests. Results: The study highlights significant disparities in education levels, toilet ownership, and healthcare access. Challenges in finding public toilets (86.67%) and accessing water sources (67.78%) are consistent across regions, with Seaside facing financial constraints (85.00%) and water cost concerns (91.67%). Attitudes toward hygiene vary, with the Mountain region having the highest ‘Never’ responses for handwashing (38.89%), and Downtown leading in water treatment practices (11.67%). There is a strong willingness to share health knowledge, particularly in Downtown (100.00%). Seaside (83.33%) and Downtown (73.33%) revealed a higher cholera awareness, while nearly half of Mountain students lacked knowledge (54.44%). Conclusions: This study highlights significant disparities in WASH practices among La Gonâve's adolescents in Downtown, Mountain, and Seaside regions. Urgent interventions are crucial for improving sanitation, ensuring clean water access, and implementing targeted hygiene education, especially in the resource-constrained Mountain and Seaside areas. The findings underscore the vital roles of adolescents and schools in disseminating knowledge, with further research needed to explore intervention differences.

Published
2024
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2. Prenatal Exposure to Parabens Affects Birth Outcomes through Maternal Glutathione S-Transferase (GST) Polymorphisms: From the Mothers and Kids Environmental Health (MAKE) Study

Author

Bohye Shin, Eun Kyo Park, Byung-Mi Kim, Seyoung Kim, Sora Kang, Eun Young Park, and Jeoung A. Kwon

Subjects
Multivariate analysis, Genotype, Health, Toxicology and Mutagenesis, Birth weight, Mothers, lcsh:Medicine, Physiology, 010501 environmental sciences, 01 natural sciences, Article, parabens, polymorphism, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pregnancy, Polymorphism (computer science), Humans, Medicine, Genetic Predisposition to Disease, 030212 general & internal medicine, Glutathione Transferase, 0105 earth and related environmental sciences, GSTT1, biology, business.industry, lcsh:R, Public Health, Environmental and Occupational Health, birth weight, Gestational age, Confidence interval, Paraben, Glutathione S-transferase, chemistry, Case-Control Studies, Prenatal Exposure Delayed Effects, biology.protein, Female, business, Environmental Health, GSTM1
Abstract

Introduction: Human exposure to parabens is very common in daily life, and prenatal exposure to these chemicals is associated with poor birth outcomes. Therefore, the aim of this study was to investigate the effect of glutathione S-transferase (GST) polymorphisms on the association between prenatal exposure to parabens and birth outcomes. Methods: We conducted a multivariate analysis involving 177 subjects to determine the association between paraben concentrations and birth outcomes in mothers with GST mu 1 (GSTM1) and GST theta 1 (GSTT1) polymorphisms from 2017 to 2019. Furthermore, we determined the interactive effect between paraben levels and GSTM1/GSTT1 polymorphisms using regression analysis, in addition to a generalized linear model after stratifying GSTM1/GSTT1 genotype into three categories. Results: Methyl and propyl paraben concentrations were significantly and positively associated with birth weight (methyl, β = 116.525, 95% confidence interval (CI) = 22.460–210.590, propyl, β = 82.352, 95% CI = 9.147–155.557) in individuals with the GSTM1-null genotype. Moreover, the propyl paraben concentration was significantly associated with an increase in gestational age (β = 0.312, 95% CI = 0.085–0.539) in individuals with the GSTM1-null genotype. Conclusions: This study reported the association between prenatal paraben exposure and birth outcomes in individuals with GST polymorphisms. We found positive relationships of maternal exposure to methyl parabens with birth weight in both mothers with GSTM1 and GSTT1-null genotypes.

Published
2021

3. Urinary bisphenol A and thyroid function by BMI in the Korean National Environmental Health Survey (KoNEHS) 2012–2014

Author

Byung-Mi Kim, Jeoung A. Kwon, and Bohye Shin

Subjects
Male, Health, Toxicology and Mutagenesis, 0208 environmental biotechnology, Thyroid Gland, Thyrotropin, 02 engineering and technology, Urine, Thyroid Function Tests, 010501 environmental sciences, 01 natural sciences, Body Mass Index, Medicine, education.field_of_study, Triiodothyronine, Thyroid, General Medicine, Middle Aged, Pollution, medicine.anatomical_structure, Environmental Pollutants, Female, Thyroid function, Environmental Health, hormones, hormone substitutes, and hormone antagonists, Adult, Thyroid Hormones, endocrine system, Environmental Engineering, Urinary system, Population, Young Adult, Phenols, Environmental health, Republic of Korea, Humans, Environmental Chemistry, Benzhydryl Compounds, education, Aged, 0105 earth and related environmental sciences, urogenital system, business.industry, Public Health, Environmental and Occupational Health, General Chemistry, Health Surveys, 020801 environmental engineering, Thyroxine, Cross-Sectional Studies, business, Body mass index, Hormone
Abstract

Bisphenol A (BPA) is one of the largest amounts of chemicals in daily life and source of polycarbonate plastics, epoxy resins, medical equipment, plastic consumer products. Recent studies reported that the effects of BPA on human health in the thyroid hormone. Therefore, this study aimed to indicate the association between urinary BPA concentration and thyroid function in total triiodothyronine (T3), thyroxine (T4), thyroidal stimulating hormone (TSH) and stratified the population by body mass index (BMI). This study was performed on 6478 adults aged 19 years and older based on the Second Korean National Environmental Health Survey (KoNEHS, 2012–2014). We measured BPA in urine and total T3, T4 and TSH in serum from the 2nd KoNEHS study. The multiple regression analysis was performed to assess the association of urinary BPA concentrations with thyroid hormone after BMI stratification. Urinary BPA associated with thyroid hormone. Especially, BPA is related to T3 (−0.627) in all group, and T4 (−0.060, −0.098) in all group and the group of BMI 25.0kg/m2 or more negatively. When stratified by BPA, T3 and T4 were significantly decreased with the high BPA exposure compared with the low BPA exposure for BMI more than 25.0kg/m2 (adjusted β = −3.402, 95% CI: 4.942, −1.862, adjusted β = −0.209, 95% CI: 0.328, −0.090). However, no obvious associations were found between BPA concentration and TSH. The results of urinary BPA decrease with T3 and T4 levels increase in the higher BMI group is a new finding which does not exist in recent studies of Korea.

Published
2020

4. Urinary Concentrations of Bisphenol-F and Their Associations with Environmental Factors of Pregnant Women: The Mother and Kids Environmental Health (MAKE) Study

Author

Bohye Shin, Eun-Kyo Park, Byung-Mi Kim, and Eun Young Park

Subjects
Food contact materials, business.industry, Bisphenol F, visual_art, Environmental health, visual_art.visual_art_medium, General Earth and Planetary Sciences, Medicine, Epoxy, business, General Environmental Science
Abstract

Background/AimBisphenol-F(BPF) is a substitute substances of bisphenol-A and the manufacturing of plastics and epoxy resins(such as food contact materials, structural adhesive). However, the exposu...

Published
2018

6. Risk factors predicting development of complications in 72 dogs with esophageal foreign bodies.

Author

Bohye Shin, Hakhyun Kim, Dongwoo Chang, Ji-Houn Kang, Byeong-Teck Kang, and Mhan-pyo Yang

Subjects
*FOREIGN bodies, *DISEASE complications, *DISEASE risk factors, *FISHER exact test, *DOGS
Abstract

The aim of this study was to determine predictive risk factors implicated in complications in dogs with esophageal foreign bodies. Medical records of 72 dogs diagnosed with esophageal foreign bodies by endoscopy were reviewed retrospectively. Factors analyzed included age; breed; gender; body weight, location, dimension, and type of foreign body; and duration of impaction. To identify risk factors associated with complications after foreign body ingestion, categorical variables were analyzed using the chisquare or Fisher's exact tests and multivariate analysis, as appropriate. Complications secondary to esophageal foreign body ingestion included megaesophagus, esophagitis, perforation, laceration, diverticulum, and pleuritis. Univariate analysis revealed that the location and duration of impaction after foreign body ingestion were associated with an increased risk of esophageal laceration and perforation. Multivariate analysis showed that age, duration of impaction, and foreign body dimension were significant independent risk factors associated with the development of complications in dogs with esophageal foreign bodies. In conclusion, these results showed that longer duration of impaction and larger foreign body dimensions may increase the risks of esophageal laceration, perforation, and plueritis in dogs. [ABSTRACT FROM AUTHOR]

Published
2019
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