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3. A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo

4. Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing

5. IDOL regulates systemic energy balance through control of neuronal VLDLR expression

6. TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis

9. Mouse Models to Study Inherited Cardiomyopathy

10. Universal toxin-based selection for precise genome engineering in human cells

11. Author Correction: Universal toxin-based selection for precise genome engineering in human cells

13. Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice

15. AMPK activation protects against diet-induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue

16. Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery

17. In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model

18. Elevated Adipocyte Membrane Phospholipid Saturation Does Not Compromise Insulin Signaling.

20. In vivo CRISPR editing with no detectable genome-wide off-target mutations

21. ELEVATED ADIPOCYTE MEMBRANE PHOSPHOLIPID SATURATION DOES NOT COMPROMISE INSULIN SIGNALING

22. Elevated Adipocyte Membrane Phospholipid Saturation Does not Compromise Insulin Signaling

23. Human genetics uncovers MAP3K15 as an obesity-independent therapeutic target for diabetes

24. Selecting the right therapeutic target for kidney disease

25. Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing

27. A Combined Human in Silico and CRISPR/Cas9-Mediated in Vivo Zebrafish Based Approach to Provide Phenotypic Data for Supporting Early Target Validation

29. Human genetic evidence supports MAP3K15 inhibition as a therapeutic strategy for diabetes

31. Exploring the Mechanisms of Recovery in Anorexia Nervosa through a Translational Approach: From Original Ecological Measurements in Human to Brain Tissue Analyses in Mice

33. Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progression

34. Human rare variant and zebrafish CRISPR/Cas9-mediated mutant analyses reveal novel functions for API5, HSPB7, and LMO2 in heart failure

35. Sphingosine 1-Phosphate Mediates Adiponectin Receptor Signaling Essential For Lipid Homeostasis And Embryogenesis

36. Allostatic hypermetabolic response in PGC1α/β heterozygote mouse despite mitochondrial defects

37. PCSK9 rs11591147 R46L loss‐of‐function variant protects against liver damage in individuals with NAFLD

40. Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity

41. Central NMU signaling in body weight and energy balance regulation: evidence from NMUR2 deletion and chronic central NMU treatment in mice

42. Effect of Growth Hormone Secretagogue Receptor Deletion on Growth, Pulsatile Growth Hormone Secretion, and Meal Pattern in Male and Female Mice

47. Acutely reduced locomotor activity is a major contributor to Western diet-induced obesity in mice

48. Mice with experimental colitis show an altered metabolism with decreased metabolic rate

49. Growth hormone receptor deficiency results in blunted ghrelin feeding response, obesity, and hypolipidemia in mice

50. PCSK9 rs11591147 R46L loss‐of‐function variant protects against liver damage in individuals with NAFLD

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