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344 results on '"Boeschoten Elisabeth W"'

1. Survival in dialysis patients is not different between patients with diabetes as primary renal disease and patients with diabetes as a co-morbid condition

Author

Schroijen Marielle A, Dekkers Olaf M, Grootendorst Diana C, Noordzij Marlies, Romijn Johannes A, Krediet Raymond T, Boeschoten Elisabeth W, and Dekker Friedo W

Subjects
Diseases of the genitourinary system. Urology, RC870-923
Abstract

Abstract Background On dialysis, survival among patients with diabetes mellitus is inferior to survival of non-diabetic patients. We hypothesized that patients with diabetes as primary renal disease have worse survival compared to patients with diabetes as a co-morbid condition and aimed to compare all-cause mortality between these patient groups. Methods Data were collected from the Netherlands Cooperative Study on the Adequacy of Dialysis (NECOSAD), a multicenter, prospective cohort study in which new patients with end stage renal disease (ESRD) were monitored until transplantation or death. Patients with diabetes as primary cause of ESRD were compared with patients with diabetes as co-morbid condition and both of these patient groups were compared to patients without diabetes. Analysis was performed using Kaplan-Meier and Cox regression. Results Fifteen % of the patients had diabetic nephropathy as primary renal disease (N = 281); 6% had diabetes as co-morbid condition (N = 107) and 79% had no diabetes (N = 1465). During follow-up 42% of patients (N = 787) died. Compared to non-diabetic patients, mortality risk was increased for both patients with diabetes as primary renal disease HR: 1.9 (95% CI 1.6, 2.3) and for patients with diabetes as co-morbid condition HR: 1.7 (95% CI 1.3, 2.2). Mortality was not significantly higher in patients with diabetes as primary renal disease compared to patients with diabetes as co-morbid condition (HR 1.06; 95% CI 0.79, 1.43). Conclusions This study in patients with ESRD showed no survival difference between patients with diabetes as primary renal disease and patients with diabetes as a co-morbid condition. Both conditions were associated with increased mortality risk compared to non-diabetic patients.

Published
2011
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2. Association of blood pressure with decline in renal function and time until the start of renal replacement therapy in pre-dialysis patients: a cohort study

Author

Sijpkens Yvo WJ, Boeschoten Elisabeth W, de Jager Dinanda J, Halbesma Nynke, Voormolen Nora, de Goeij Moniek CM, Dekker Friedo W, and Grootendorst Diana C

Subjects
blood pressure, chronic kidney disease stages IV-V, estimated glomerular filtration rate, pre-dialysis care, renal replacement therapy, Diseases of the genitourinary system. Urology, RC870-923
Abstract

Abstract Background To investigate whether high blood pressure accelerates renal function decline in patients with advanced chronic kidney disease (CKD), we studied the association of systolic (SBP) and diastolic blood pressure (DBP) with decline in renal function and time until the start of renal replacement therapy (RRT) in patients with CKD stages IV-V on pre-dialysis care. Methods In the PREPARE-1 cohort 547 incident pre-dialysis patients, referred as part of the usual care to outpatient clinics of eight Dutch hospitals, were included between 1999 and 2001 and followed until the start of RRT, mortality, or end of follow-up (January 1st 2008). Main outcomes were rate of decline in renal function, estimated as the slope of available eGFR measurements, and time until the start of RRT. Results A total of 508 patients, 57% men and median (IQR) age of 63 (50-73) years, were available for analyses. Mean (SD) decline in renal function was 0.35 (0.75) ml/min/1.73 m2/month. Every 10 mmHg increase in SBP or DBP resulted in an accelerated decline in renal function (adjusted additional decline 0.04 (0.02;0.07) and 0.05 (0.00;0.11) ml/min/1.73 m2/month respectively) and an earlier start of RRT (adjusted HR 1.09 (1.04;1.14) and 1.16 (1.05;1.28) respectively). Furthermore, patients with SBP and DBP above the BP target goal of < 130/80 mmHg experienced a faster decline in renal function (adjusted additional decline 0.31 (0.08;0.53) ml/min/1.73 m2/month) and an earlier start of RRT (adjusted HR 2.08 (1.25;3.44)), compared to patients who achieved the target goal (11%). Comparing the decline in renal function and risk of starting RRT between patients with only SBP above the target (≥ 130 mmHg) and patients with both SBP and DBP below the target (< 130/80 mmHg), showed that the results were almost similar as compared to patients with both SBP and DBP above the target (adjusted additional decline 0.31 (0.04;0.58) ml/min/1.73 m2/month and adjusted HR 2.24 (1.26;3.97)). Therefore, it seems that especially having SBP above the target is harmful. Conclusions In pre-dialysis patients with CKD stages IV-V, having blood pressure (especially SBP) above the target goal for CKD patients (< 130/80 mmHg) was associated with a faster decline in renal function and a later start of RRT.

Published
2011
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3. Pre-dialysis patients' perceived autonomy, self-esteem and labor participation: associations with illness perceptions and treatment perceptions. A cross-sectional study

Author

Kaptein Ad A, Heijmans Monique, Rijken Mieke, Grootendorst Diana C, Jansen Daphne L, Boeschoten Elisabeth W, and Dekker Friedo W

Subjects
Diseases of the genitourinary system. Urology, RC870-923
Abstract

Abstract Background Compared to healthy people, patients with chronic kidney disease (CKD) participate less in paid jobs and social activities. The aim of the study was to examine a) the perceived autonomy, self-esteem and labor participation of patients in the pre-dialysis phase, b) pre-dialysis patients' illness perceptions and treatment perceptions, and c) the association of these perceptions with autonomy, self-esteem and labor participation. Methods Patients (N = 109) completed questionnaires at home. Data were analysed using bivariate and multivariate analyses. Results The results showed that the average autonomy levels were not very high, but the average level of self-esteem was rather high, and that drop out of the labor market already occurs during the pre-dialysis phase. Positive illness and treatment beliefs were associated with higher autonomy and self-esteem levels, but not with employment. Multiple regression analyses revealed that illness and treatment perceptions explained a substantial amount of variance in autonomy (17%) and self-esteem (26%). The perception of less treatment disruption was an important predictor. Conclusions Patient education on possibilities to combine CKD and its treatment with activities, including paid work, might stimulate positive (realistic) beliefs and prevent or challenge negative beliefs. Interventions focusing on these aspects may assist patients to adjust to CKD, and ultimately prevent unnecessary drop out of the labor market.

Published
2010
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4. Sodium Restriction in Patients With CKD: A Randomized Controlled Trial of Self-management Support

Author

van Dijk, Sandra, Meuleman, Yvette, Dekker, Friedo W., Hoekstra, Tiny, Navis, Gerjan, Vogt, Liffert, van der Boog, Paul J.M., Bos, Willem Jan W., van Montfrans, Gert A., Boeschoten, Elisabeth W., Verduijn, Marion, ten Brinke, Lucia, Spijker, Anke, Kwakernaak, Arjan J., Humalda, Jelmer K., van Hirtum, Tonnie, Bokelaar, Robin, Loos, Marie-Louise, Bakker-Edink, Anke, Poot, Charlotte, Ciere, Yvette, Zwaard, Sophie, Veldscholte, Glenn, Heuveling, Lara, Storm, Marjolein, and Prantl, Karen

Published
2017
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5. Perceived Sodium Reduction Barriers Among Patients with Chronic Kidney Disease: Which Barriers Are Important and Which Patients Experience Barriers?

Author

Meuleman, Yvette, Hoekstra, Tiny, Dekker, Friedo W., van der Boog, Paul J. M., van Dijk, Sandra, van Dijk, Sandra, Meuleman, Yvette, Dekker, Friedo W., Hoekstra, Tiny, Navis, Gerjan, Vogt, Liffert, van der Boog, Paul J. M., Bos, Willem Jan W., van Montfrans, Gert A., Boeschoten, Elisabeth W., Verduijn, Marion, ten Brinke, Lucia, Heuveling, Lara, Storm, Marjolein, Prantl, Karen, Spijker, Anke, Kwakernaak, Arjan J., Humalda, Jelmer K., van Hirtum, Tonnie, Bokelaar, Robin, Loos, Marie-Louise, Bakker-Edink, Anke, Poot, Charlotte, Ciere, Yvette, Zwaard, Sophie, Veldscholte, Glenn, and The ESMO study group

Published
2017
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6. The role of social support in dialysis patients' feelings of autonomy and self-esteem: is support more beneficial for patients with specific illness perceptions?

Author

Jansen, Daphne L., Rijken, Mieke, Boeschoten, Elisabeth W., Kaptein, Ad. A., Dekker, Friedo W., and Groenewegen, Peter P.

Subjects
Health aspects -- Social aspects -- Prognosis, Family and marriage, Health, Psychology and mental health
Abstract

The purpose of this study was to investigate whether effects of various types of support on dialysis patients' perceived autonomy and self-esteem depend on patients' perceived concerns and personal control [...]

Published
2014
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