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13 results on '"Boehmer, Merle"'

2. One Health in action: Investigation of the first detected local cluster of fatal borna disease virus 1 (BoDV-1) encephalitis, Germany 2022

Author

Böhmer, Merle M., Haring, Viola C., Schmidt, Barbara, Saller, Franziska S., Coyer, Liza, Chitimia-Dobler, Lidia, Dobler, Gerhard, Tappe, Dennis, Bonakdar, Andrea, Ebinger, Arnt, Knoll, Gertrud, Eidenschink, Lisa, Rohrhofer, Anette, Niller, Hans Helmut, Katz, Katharina, Starcky, Philip, Beer, Martin, Ulrich, Rainer G., Rubbenstroth, Dennis, and Bauswein, Markus

Published
2024
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5. Spatially resolved qualified sewage spot sampling to track SARS-CoV-2 dynamics in Munich - One year of experience

Author

Emad, Alamoudi, Jared, Anderson, Abhishek, Bakuli, Maxilmilian, Baumann, Marc, Becker, Franziska, Bednarzki, Olimbek, Bemirayev, Jessica, Beyerl, Patrick, Bitzer, Rebecca, Böhnlein, Isabel, Brand, Jan, Bruger, Friedrich, Caroli, Noemi, Castelletti, Josephine, Coleman, Lorenzo, Contento, Alina, Czwienzek, Flora, Deák, Diefenbach Maximilian, N., Jana, Diekmannshemke, Gerhard, Dobler, Jürgen, Durner, Ute, Eberle, Judith, Eckstein, Tabea, Eser, Philine, Falk, Manuela, Feyereisen, Volker, Fingerle, Felix, Forster, Turid, Frahnow, Jonathan, Frese, Günter, Fröschl, Christiane, Fuchs, Mercè, Garí, Otto, Geisenberger, Christof, Geldmacher, Leonard, Gilberg, Kristina, Gillig, Philipp, Girl, Elias, Golschan, Michelle, Guggenbuehl Noller Jessica, Maria, Guglielmini Elena, Pablo, Gutierrez, Anslem, Haderer, Marlene, Hannes, Lena, Hartinger, Jan, Hasenauer, Alejandra, Hernandez, Leah, Hillari, Christian, Hinske, Tim, Hofberger, Michael, Hölscher, Sacha, Horn, Kristina, Huber, Christian, Janke, Ursula, Kappl, Antonia, Keßler, Zohaib, Khan, Johanna, Kresin, Inge, Kroidl, Arne, Kroidl, Magdalena, Lang, Clemens, Lang, Silvan, Lange, Michael, Laxy, Ronan, Le Gleut, Reiner, Leidl, Leopold, Liedl, Xhovana, Lucaj, Fabian, Luppa, Sophie, Nafziger Alexandra, Petra, Mang, Alisa, Markgraf, Rebecca, Mayrhofer, Dafni, Metaxa, Hannah, Müller, Katharina, Müller, Laura, Olbrich, Ivana, Paunovic, Michael, Plank, Claire, Pleimelding, Michel, Pletschette, Michael, Pritsch, Stephan, Prückner, Kerstin, Puchinger, Peter, Pütz, Katja, Radon, Elba, Raimundéz, Jakob, Reich, Friedrich, Riess, Camilla, Rothe, Raquel, Rubio-Acero, Viktoria, Ruci, Elmar, Saathoff, Nicole, Schäfer, Yannik, Schälte, Benedikt, Schluse, Lara, Schneider, Mirjam, Schunk, Lars, Schwettmann, Alba, Soler, Peter, Sothmann, Kathrin, Strobl, Jeni, Tang, Fabian, Theis, Verena, Thiel, Sophie, Thiesbrummel, Vincent, Vollmayr, Emilia, Von Lovenberg, Jonathan, Von Lovenberg, Julia, Waibel, Claudia, Wallrauch, Andreas, Wieser, Simon, Winter, Roman, Wölfel, Julia, Wolff, Tobias, Würfel, Sabine, Zange, Eleftheria, Zeggini, Anna, Zielke, Thorbjörn, Zimmer, Rubio-Acero, Raquel, Beyerl, Jessica, Muenchhoff, Maximilian, Roth, Marc Sancho, Castelletti, Noemi, Paunovic, Ivana, Radon, Katja, Springer, Bernd, Nagel, Christian, Boehm, Bernhard, Böhmer, Merle M., Graf, Alexander, Blum, Helmut, Krebs, Stefan, Keppler, Oliver T., Osterman, Andreas, Khan, Zohaib Nisar, Hoelscher, Michael, and Wieser, Andreas

Published
2021
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6. A Public Health Antibody Screening Indicates a 6-Fold Higher SARS-CoV-2 Exposure Rate than Reported Cases in Children

Author

Hippich, Markus, Holthaus, Lisa, Assfalg, Robin, Zapardiel-Gonzalo, Jose, Kapfelsperger, Heidi, Heigermoser, Martin, Haupt, Florian, Ewald, Dominik A., Welzhofer, Tiziana C., Marcus, Benjamin A., Heck, Susanne, Koelln, Annika, Stock, Joanna, Voss, Franziska, Secchi, Massimiliano, Piemonti, Lorenzo, de la Rosa, Kathrin, Protzer, Ulrike, Boehmer, Merle, Achenbach, Peter, Lampasona, Vito, Bonifacio, Ezio, and Ziegler, Anette-Gabriele

Published
2021
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7. Investigation of a COVID-19 outbreak in Germany resulting from a single travel-associated primary case: a case series

Author

Böhmer, Merle M, Buchholz, Udo, Corman, Victor M, Hoch, Martin, Katz, Katharina, Marosevic, Durdica V, Böhm, Stefanie, Woudenberg, Tom, Ackermann, Nikolaus, Konrad, Regina, Eberle, Ute, Treis, Bianca, Dangel, Alexandra, Bengs, Katja, Fingerle, Volker, Berger, Anja, Hörmansdorfer, Stefan, Ippisch, Siegfried, Wicklein, Bernd, Grahl, Andreas, Pörtner, Kirsten, Muller, Nadine, Zeitlmann, Nadine, Boender, T Sonia, Cai, Wei, Reich, Andreas, an der Heiden, Maria, Rexroth, Ute, Hamouda, Osamah, Schneider, Julia, Veith, Talitha, Mühlemann, Barbara, Wölfel, Roman, Antwerpen, Markus, Walter, Mathias, Protzer, Ulrike, Liebl, Bernhard, Haas, Walter, Sing, Andreas, Drosten, Christian, and Zapf, Andreas

Published
2020
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13. Public health antibody screening indicates a six-fold higher SARS-CoV-2 exposure rate than reported cases in children

Author

Ulrike Protzer, Peter Achenbach, Ezio Bonifacio, Susanne Heck, Merle Boehmer, Franziska Voss, Lisa Holthaus, Anette-Gabriele Ziegler, Martin Heigermoser, Tiziana C. Welzhofer, Joanna Stock, Dominik A. Ewald, F Haupt, Heidi Kapfelsperger, Lorenzo Piemonti, Benjamin A. Marcus, Markus Hippich, Annika Koelln, Jose Zapardiel-Gonzalo, Vito Lampasona, Kathrin de la Rosa, Robin Assfalg, Massimiliano Secchi, Hippich, Marku, Holthaus, Lisa, Assfalg, Robin, Zapardiel Gonzalo, Jose M, Kapfelsperger, Heidi, Heigermoser, Martin, Haupt, Florian, Ewald, Dominik A, Welzhofer, Tiziana C, Marcus, Benjamin A, Heck, Susanne, Koelln, Annika, Stock, Joanna, Voss, Franziska, Secchi, Massimiliano, Piemonti, Lorenzo, Rosa, Kathrin de la, Protzer, Ulrike, Boehmer, Merle, Achenbach, Peter, Lampasona, Vito, Bonifacio, Ezio, and Ziegler, Anette-Gabriele

Subjects
nucleocapsid antigen, medicine.medical_specialty, Materials Science (miscellaneous), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Population, Antibodies, Viral, Virus, receptor binding domain RBD, Internal medicine, Pandemic, medicine, Seroprevalence, Humans, education, Child, SARS-CoV-2 antibody, Type 1 diabetes, education.field_of_study, public health screening, biology, seroprevalence, business.industry, SARS-CoV-2, Public health, Infant, Newborn, COVID-19, Clinical Advances, General Medicine, medicine.disease, Diabetes Mellitus, Type 1, biology.protein, Public Health, Antibody, business
Abstract

Background Antibody responses to virus reflect exposure and potential protection. Methods We developed a highly specific and sensitive approach to measuring antibodies against SARS-CoV-2 for population-scale immune surveillance. Antibody positivity was defined as a dual-positive response against both the receptor binding domain and nucleocapsid proteins of SARS-CoV-2. Antibodies were measured by immuno-precipitation assays in capillary blood from 15,771 children aged 1 to 18 years living in Bavaria, Germany, and participating in a public health type 1 diabetes screening program (Clinicaltrials.gov NCT04039945), in 1,916 dried blood spots from neonates in a Bavarian screening study (Clinicaltrials.gov NCT03316261), and in 75 SARS-CoV-2 positive individuals. Virus positive incidence was obtained from Bavarian health authority data. Findings. Dual-antibody positivity was detected in none of 3887 children in 2019 (100% specificity) and 73 of 75 SARS-CoV-2 positive individuals (97.3% sensitivity). Antibody surveillance in children during 2020 resulted in frequencies of 0.08% in January to March, 0.61% in April, 0.74% in May, 1.13% in June and 0.91% in July. Antibody prevalence from April 2020 was six-fold higher than the incidence of authority-reported cases (156 per 100,000 children), showed marked variation between the seven Bavarian regions (P, Graphical Abstract, Highlights • SARS-CoV-2 dual antibody strategy yielded 100% specificity and >95% sensitivity • Childhood surveillance finds 6-fold higher antibody prevalence than reported cases • Half of the antibody positive children were asymptomatic • No association found between SARS-Cov-2 antibodies and type 1 diabetes autoimmunity, Hippich et al developed a highly specific and sensitive dual antibody strategy for public health surveillance of SARS-CoV-2 antibody prevalence. In testing more than 11,000 children in Germany, they report an antibody prevalence that is six-fold higher than the health authority-reported SARS-CoV-2 incidence, including 50% of antibody-positive children without symptoms.

Published
2020

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