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125 results on '"Boehmer, Annemie"'

3. Nasopharyngeal microbiota in children is associated with severe asthma exacerbations

Author

Infectieziekten onderzoek3 (Bogaert), Infection & Immunity, Infectieziekten onderzoek1 (Bont), Onderzoek, Child Health, van Beveren, Gina J., de Steenhuijsen Piters, Wouter A.A., Boeschoten, Shelley A., Louman, Sam, Chu, Mei Ling, Arp, Kayleigh, Fraaij, Pieter L., de Hoog, Matthijs, Buysse, Corinne, van Houten, Marlies A., Sanders, Elisabeth A.M., Merkus, Peter J.F.M., Boehmer, Annemie L., Bogaert, Debby, Infectieziekten onderzoek3 (Bogaert), Infection & Immunity, Infectieziekten onderzoek1 (Bont), Onderzoek, Child Health, van Beveren, Gina J., de Steenhuijsen Piters, Wouter A.A., Boeschoten, Shelley A., Louman, Sam, Chu, Mei Ling, Arp, Kayleigh, Fraaij, Pieter L., de Hoog, Matthijs, Buysse, Corinne, van Houten, Marlies A., Sanders, Elisabeth A.M., Merkus, Peter J.F.M., Boehmer, Annemie L., and Bogaert, Debby

Published
2024

6. Oxygen saturation targets for children with respiratory distress:a systematic review

Author

Louman, Sam, van Stralen, Karlijn J., Pijnenburg, Mariëlle W.H., Koppelman, Gerard H., Boehmer, Annemie L.M., Louman, Sam, van Stralen, Karlijn J., Pijnenburg, Mariëlle W.H., Koppelman, Gerard H., and Boehmer, Annemie L.M.

Abstract

Background:In children with respiratory distress, supplemental oxygen is indicated at peripheral oxygen saturation (SpO2) thresholds of 90–94%. However, these thresholds are poorly studied. We conducted a systematic review to summarise the existing evidence for SpO2 thresholds in children with respiratory distress. Methods:Electronic databases and registries were searched for original articles published from 1 January 2010 to 7 January 2022 comparing two or more SpO2 thresholds in children with respiratory distress. Primary outcomes were safety, including mortality, neurocognitive outcomes and readmissions, and effectiveness, including admission rate and length of hospital stay. Methodological appraisal was performed using the Cochrane Risk of Bias 2 (RoB-2) or Risk of Bias in Non-Randomized Studies – of Interventions (ROBINS-I) tools. Results were narratively synthesised. Results:We retrieved 3384 results; seven studies were included. Lower thresholds ranged from 80% to 92% and were compared with higher thresholds ranging from 92% to 94%. Studies were highly heterogeneous in setting, design, population and outcomes. Risk of bias varied from low to high. Lower SpO2 thresholds had equivalent mortality, neurocognitive outcomes and readmissions or re-attendance to healthcare to higher thresholds. Lower SpO2 thresholds showed a significant decrease in admission rates by up to 40% and shortened hospitalisation duration by 10–18 h. Conclusions:The current SpO2 thresholds of 90–94% in children with respiratory distress may be too high, which could lead to unnecessary hospitalisations and prolonged hospitalisation duration. SpO2 thresholds as low as 88% are potentially safe in children with respiratory distress and may reduce hospitalisation rates and length of stay. However, high-quality evidence is needed to support t

Published
2023

8. It Is Not Just the FEV1 That Matters, but the Personal Goals We Reach Along the Way: Qualitative, Multicenter, Prospective, Observational Study

Author

Oppelaar, M.C., Wijngaart, L.S. van den, Merkus, P.J.F.M., Croonen, E.A., Hugen, C.A.C., Brouwer, M.L., Boehmer, Annemie L.M., Roukema, J., Oppelaar, M.C., Wijngaart, L.S. van den, Merkus, P.J.F.M., Croonen, E.A., Hugen, C.A.C., Brouwer, M.L., Boehmer, Annemie L.M., and Roukema, J.

Abstract

Contains fulltext : 240767.pdf (Publisher’s version ) (Open Access)

Published
2021

11. Efficacy of A Loading Dose of IV Salbutamol in Children With Severe Acute Asthma Admitted to A PICU: A Randomized Controlled Trial

Author

Boeschoten, Shelley A, primary, Buysse, Corinne M., additional, Winter, Brenda C. de, additional, Rosmalen, Joost van, additional, Jongste, Johan C. de, additional, Jonge, Rogier C. de, additional, Heisterkamp, Sabien G., additional, Woensel, Job B. van, additional, Kneyber, Martin C., additional, Zwol, Annelies van, additional, Boehmer, Annemie L., additional, Hoog, Matthijs de, additional, and (SKIC), Dutch collaborative PICU research network, additional

Published
2021
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12. Preschool wheezing

Author

Brand, Paul L.P., primary, Boehmer, Annemie M., additional, and Vaessen-Verberne, Anja A.P.H., additional

Published
2013
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14. Risk factors for intensive care admission in children with severe acute asthma in the Netherlands: a prospective multicentre study

Author

Boeschoten, Shelley A., primary, Boehmer, Annemie L., additional, Merkus, Peter J., additional, van Rosmalen, Joost, additional, de Jongste, Johan C., additional, Fraaij, Pieter L.A., additional, Molenkamp, Richard, additional, Heisterkamp, Sabien G., additional, van Woensel, Job B., additional, Kapitein, Berber, additional, Haarman, Eric G., additional, Wösten-van Asperen, Roelie M., additional, Kneyber, Martin C., additional, Lemson, Joris, additional, Hartman, Stan, additional, van Waardenburg, Dick A., additional, Bunker-Wiersma, Heleen E., additional, Brouwer, Carole N., additional, van Ewijk, Bart E., additional, Landstra, Anneke M., additional, Verwaal, Mariel, additional, Vaessen-Verberne, Anja A., additional, Hammer, Sanne, additional, Buysse, Corinne M., additional, and de Hoog, Matthijs, additional

Published
2020
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15. Quality of life and psychosocial outcomes in children with severe acute asthma and their parents

Author

Boeschoten, Shelley, Dulfer, Karolijn, Boehmer, Annemie, Merkus, PJFM, van Rosmalen, Joost, Jongste, Johan, de Hoog, Matthijs, Buysse, Corinne, Heisterkamp, S, van Woensel, J, Haarman, E, Kapitein, Berber, Wösten-van Asperen, R, Kneyber, M, Lemson, J, Hartman, S, Van Waardenburg, D, Bunker, H, Brouwer, C, van Ewijk, B, Landstra, A, Verwaal, M, Vaessen-Verberne, A, Hammer, S, Pediatric Surgery, Epidemiology, Pediatrics, Sociology, Pediatric surgery, Amsterdam Reproduction & Development (AR&D), Paediatric Intensive Care, and AII - Inflammatory diseases

Subjects
Pulmonary and Respiratory Medicine, Pediatrics, medicine.medical_specialty, PICU, Psychological intervention, 03 medical and health sciences, Intrusion, 0302 clinical medicine, Quality of life, status asthmaticus, 030225 pediatrics, Intensive care, follow-up, Medicine, Response rate (survey), follow‐up, business.industry, parents, Original Articles, Asthma, Posttraumatic stress, 030228 respiratory system, Pediatrics, Perinatology and Child Health, Original Article, business, Psychosocial, Severe acute asthma
Abstract

To prospectively evaluate quality of life (QoL) and psychosocial outcomes in children with severe acute asthma (SAA) after pediatric intensive care (PICU) admission compared to children with SAA who were admitted to a general ward (GW). In addition, we assessed post-traumatic stress (PTS) and asthma-related QoL in the parents.A preplanned follow-up of 3-9 months of our nationwide prospective multicenter study, in which children with SAA admitted to a Dutch PICU (n=110) or GW (n=111) were enrolled between 2016-2018. Asthma-related QoL, PTS symptoms, emotional and behavioral problems, and social impact in children and/or parents were assessed with validated web-based questionnaires.We included 100 children after PICU and 103 after GW admission, with a response rate of 50% for the questionnaires. Median time to follow-up was 5 months (range 1-12 months). Time to reach full schooldays after admission was significantly longer in the PICU group (mean of 10 vs 4 days, p=0.001). Parents in the PICU group reported more PTS symptoms (intrusion p=0.01, avoidance p=0.01, arousal p=0.02) compared to the GW group.No significant differences were found between PICU and GW children on self-reported outcome domains, except for the time to reach full schooldays. PICU parents reported PTS symptoms more often than the GW group. Therefore, monitoring asthma symptoms and psychosocial screening of children and parents after PICU admission should both be part of standard care after SAA. This should identify those who are at risk for developing PTSD, in order to timely provide appropriate interventions. This article is protected by copyright. All rights reserved.

Published
2020
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16. Population Pharmacokinetics of Intravenous Salbutamol in Children with Refractory Status Asthmaticus

Author

Vet, N.J., Winter, Brenda C.M. de, Koninckx, Muriel, Boeschoten, Shelley A., Boehmer, Annemie L.M., Verhallen, Jacintha T., Wildt, S.N. de, Koch, Birgit C.P., Hoog, M. de, Vet, N.J., Winter, Brenda C.M. de, Koninckx, Muriel, Boeschoten, Shelley A., Boehmer, Annemie L.M., Verhallen, Jacintha T., Wildt, S.N. de, Koch, Birgit C.P., and Hoog, M. de

Abstract

Contains fulltext : 217393.pdf (Publisher’s version ) (Open Access)

Published
2020

17. Population Pharmacokinetics of Intravenous Salbutamol in Children with Refractory Status Asthmaticus

Author

Vet, Nienke, Winter, Brenda, Koninckx, Muriel, Boeschoten, SA, Boehmer, Annemie, Verhallen, JT, Pl?tz, FB, Vaessen-Verberne, AA, Nagel, Bart, Knibbe, Catherijne, Buysse, Corinne, Wildt, Saskia, Koch, Birgit, Hoog, Matthijs, Vet, Nienke, Winter, Brenda, Koninckx, Muriel, Boeschoten, SA, Boehmer, Annemie, Verhallen, JT, Pl?tz, FB, Vaessen-Verberne, AA, Nagel, Bart, Knibbe, Catherijne, Buysse, Corinne, Wildt, Saskia, Koch, Birgit, and Hoog, Matthijs

Published
2020

18. Risk factors for intensive care admission in children with severe acute asthma in the Netherlands: a prospective multicentre study

Author

Intensive care patientenzorg, Child Health, Boeschoten, Shelley A, Boehmer, Annemie L, Merkus, Peter J, van Rosmalen, Joost, de Jongste, Johan C, Fraaij, Pieter L A, Molenkamp, Richard, Heisterkamp, Sabien G, van Woensel, Job B, Kapitein, Berber, Haarman, Eric G, Wösten-van Asperen, Roelie M, Kneyber, Martin C, Lemson, Joris, Hartman, Stan, van Waardenburg, Dick A, Bunker-Wiersma, Heleen E, Brouwer, Carole N, van Ewijk, Bart E, Landstra, Anneke M, Verwaal, Mariel, Vaessen-Verberne, Anja A, Hammer, Sanne, Buysse, Corinne M, de Hoog, Matthijs, Intensive care patientenzorg, Child Health, Boeschoten, Shelley A, Boehmer, Annemie L, Merkus, Peter J, van Rosmalen, Joost, de Jongste, Johan C, Fraaij, Pieter L A, Molenkamp, Richard, Heisterkamp, Sabien G, van Woensel, Job B, Kapitein, Berber, Haarman, Eric G, Wösten-van Asperen, Roelie M, Kneyber, Martin C, Lemson, Joris, Hartman, Stan, van Waardenburg, Dick A, Bunker-Wiersma, Heleen E, Brouwer, Carole N, van Ewijk, Bart E, Landstra, Anneke M, Verwaal, Mariel, Vaessen-Verberne, Anja A, Hammer, Sanne, Buysse, Corinne M, and de Hoog, Matthijs

Published
2020

20. Genotype Versus Phenotype in Families with Androgen Insensitivity Syndrome

Author

Boehmer, Annemie L. M, Brüggenwirth, Hennie, van Assendelft, Cissy, Otten, Barto J, Verleun-Mooijman, Marja C. T, Niermeijer, Martinus F, Brunner, Han G, Rouwé, Catrienus W, Waelkens, J J, Oostdijk, Wilma, Kleijer, Wim J, van der Kwast, Theo H, de Vroede, Monique A, and Drop, Stenvert L. S

Published
2001

22. It Is Not Just the FEV1 That Matters, but the Personal Goals We Reach Along the Way: Qualitative, Multicenter, Prospective, Observational Study.

Author

Oppelaar, Martinus C, Wijngaart, Lara S van den, Merkus, Peter J F M, Croonen, Ellen A, Hugen, Cindy A C, Brouwer, Marianne L, Boehmer, Annemie L M, and Roukema, Jolt

Abstract

Background: The COVID-19 pandemic has boosted the use of forced expiratory volume in 1 second (FEV1 ) telemonitoring in pediatric asthma, but a consensus on its most efficient and effective implementation is still lacking. To find answers, it is important to study how such an intervention is perceived, experienced, and used by both patients and health care professionals (HCPs). Objective: The aim of this study was to provide perspectives on how FEV1 home monitoring should be used in pediatric asthma. Methods: This is a qualitative, multicenter, prospective, observational study which included patients with asthma aged 6-16 and HCPs. Primary outcomes were results of 2 surveys that were sent to all participants at study start and after 3-4 months. Secondary outcomes consisted of FEV1 device usage during 4 months after receiving the FEV1 device. Results: A total of 39 participants (26 patients and 13 HCPs) were included in this study. Survey response rates were 97% (38/39) at the start and 87% (34/39) at the end of the study. Both patients and HCPs were receptive toward online FEV1 home monitoring and found it contributive to asthma control, self-management, and disease perception. The main concerns were about reliability of the FEV1 device and validity of home-performed lung function maneuvers. FEV1 devices were used with a median frequency of 7.5 (IQR 3.3-25.5) during the 4-month study period. Conclusions: Patients and HCPs are receptive toward online FEV1 home monitoring. Frequency of measurements varied largely among individuals, yet perceived benefits remained similar. This emphasizes that online FEV1 home monitoring strategies should be used as a means to reach individual goals, rather than being a goal on their own. [ABSTRACT FROM AUTHOR]

Published
2021
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23. A Loading Dose of IV Salbutamol in an Adolescent with Severe Acute Asthma and Cardiac Arrest

Author

Boeschoten, Shelley A., van der Crabben, Ruben S., Boehmer, Annemie L. M., de Hoog, Matthijs, and Buysse, Corinne M. P.

Subjects
Article Subject
Abstract

Severe acute asthma (SAA) can lead to respiratory failure and can be fatal. For rational use of intravenous (IV) bronchodilators, evidence regarding the pharmacokinetics and pharmacodynamics is lacking in children. The use of a loading dose IV salbutamol is not mentioned in any international guideline, and its use varies greatly between PICUs worldwide. We describe a 17-year-old Caucasian female with SAA resulting in an out-of-hospital cardiac arrest. After basic life support and return of spontaneous circulation, the ambulance administered oxygen, inhaled salbutamol, IV magnesium sulphate, and systemic corticosteroids. Despite of this, she was still in severe respiratory distress. Therefore, a loading dose of IV salbutamol was administered, after which an immediate improvement was observed. Having a loading dose of IV salbutamol available for emergency medical services use for SAA in children with life-threatening SAA in the out-of-hospital setting is important to consider. Further study on the dose and the effect of a loading dose IV salbutamol in children with SAA is necessary.

Published
2019
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24. 17β-Hydroxysteroid Dehydrogenase-3 Deficiency: Diagnosis, Phenotypic Variability, Population Genetics, and Worldwide Distribution of Ancient and de Novo Mutations*

Author

Boehmer, Annemie LM, Brinkmann, Albert O, Sandkuijl, Lodewijk A, Halley, Dicky JJ, Niermeijer, Martinus F, Andersson, Stefan, de Jong, Frank H, Kayserili, Hülya, de Vroede, Monique A, Otten, Barto J, Rouwé, Catrienus W, Mendonça, Berenice B, Rodrigues, Cidade, Bode, Hans H, de Ruiter, Petra E, Delemarre-van de Waal, Henriette A, and Drop, Stenvert LS

Published
1999

28. Population Pharmacokinetics of Intravenous Salbutamol in Children with Refractory Status Asthmaticus

Author

Vet, Nienke J., primary, de Winter, Brenda C. M., additional, Koninckx, Muriel, additional, Boeschoten, Shelley A., additional, Boehmer, Annemie L. M., additional, Verhallen, Jacintha T., additional, Plötz, Frans B., additional, Vaessen-Verberne, Anja A., additional, van der Nagel, Bart C. H., additional, Knibbe, Catherijne A. J., additional, Buysse, Corinne M. P., additional, de Wildt, Saskia N., additional, Koch, Birgit C. P., additional, and de Hoog, Matthijs, additional

Published
2019
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29. Episodic viral wheeze and multiple‐trigger wheeze in preschool children are neither distinct nor constant patterns. A prospective multicenter cohort study in secondary care

Author

Raaymakers, Maud J. A., primary, Brand, Paul L. P., additional, Landstra, Anneke M., additional, Brouwer, Marianne L., additional, Balemans, Walter A. F., additional, Niers, Laetitia E. M., additional, Merkus, Peter J. F. M., additional, Boehmer, Annemie L. M., additional, Kluytmans, Jan A. J. W., additional, Jongste, Johan C., additional, Pijnenburg, Marielle W. H., additional, and Vaessen‐Verberne, Anja A. P. H., additional

Published
2019
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32. Barriers and Facilitators When Implementing Web-Based Disease Monitoring and Management as a Substitution for Regular Outpatient Care in Pediatric Asthma: Qualitative Survey Study

Author

van den Wijngaart, Lara S, primary, Geense, Wytske W, additional, Boehmer, Annemie LM, additional, Brouwer, Marianne L, additional, Hugen, Cindy AC, additional, van Ewijk, Bart E, additional, Koenen-Jacobs, Marie-José, additional, Landstra, Anneke M, additional, Niers, Laetitia EM, additional, van Onzenoort-Bokken, Lonneke, additional, Ottink, Mark D, additional, Rikkers-Mutsaerts, Eleonora RVM, additional, Groothuis, Iris, additional, Vaessen-Verberne, Anja A, additional, Roukema, Jolt, additional, and Merkus, Peter JFM, additional

Published
2018
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33. Substitution of outpatient care in asthmatic children by online monitoring:Barriers and facilitators for implementation

Author

van den Wijngaart, Lara, primary, Geense, Wytske W., additional, Boehmer, Annemie L.M., additional, Brouwer, Marianne L., additional, Hugen, Cindy A.C., additional, van Ewijk, Bart E., additional, Koenen, Mariejose, additional, Landstra, Anneke M., additional, Niers, Laetitia E.M., additional, van Onzenoort, Lonneke, additional, Ottink, Mark D., additional, Rikkers-Mutsaerts, Eleonora R.V.M., additional, Groothuis, Iris, additional, Vaessen-Verberne, Anja A., additional, Roukema, Jolt, additional, and Merkus, Peter J.F.M., additional

Published
2018
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34. Children with severe acute asthma admitted to Dutch PICUs: A changing landscape

Author

Boeschoten, Shelley, Buysse, Corinne, Merkus, P, van Wijngaarden, JMC, Heisterkamp, SGJ, Jongste, Johan, van Rosmalen, Joost, Cochius - den Otter, Suzan, Boehmer, Annemie, de Hoog, Matthijs, Boeschoten, Shelley, Buysse, Corinne, Merkus, P, van Wijngaarden, JMC, Heisterkamp, SGJ, Jongste, Johan, van Rosmalen, Joost, Cochius - den Otter, Suzan, Boehmer, Annemie, and de Hoog, Matthijs

Published
2018

35. Barriers and Facilitators When Implementing Web-Based Disease Monitoring and Management as a Substitution for Regular Outpatient Care in Pediatric Asthma: Qualitative Survey Study (Preprint)

Author

van den Wijngaart, Lara S, primary, Geense, Wytske W, additional, Boehmer, Annemie LM, additional, Brouwer, Marianne L, additional, Hugen, Cindy AC, additional, van Ewijk, Bart E, additional, Koenen-Jacobs, Marie-José, additional, Landstra, Anneke M, additional, Niers, Laetitia EM, additional, van Onzenoort-Bokken, Lonneke, additional, Ottink, Mark D, additional, Rikkers-Mutsaerts, Eleonora RVM, additional, Groothuis, Iris, additional, Vaessen-Verberne, Anja A, additional, Roukema, Jolt, additional, and Merkus, Peter JFM, additional

Published
2017
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36. A virtual asthma clinic for children: fewer routine outpatient visits, same asthma control

Author

van den Wijngaart, Lara S., primary, Roukema, Jolt, additional, Boehmer, Annemie L.M., additional, Brouwer, Marianne L., additional, Hugen, Cindy A.C., additional, Niers, Laetitia E.M., additional, Sprij, Arwen J., additional, Rikkers-Mutsaerts, Eleonora R.V.M., additional, Rottier, Bart L., additional, Donders, A. Rogier T., additional, Verhaak, Chris M., additional, Pijnenburg, Mariëlle W., additional, and Merkus, Peter J.F.M., additional

Published
2017
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37. Online asthma management for children is cost-effective

Author

van den Wijngaart, Lara S., primary, Kievit, Wietske, additional, Roukema, Jolt, additional, Boehmer, Annemie L.M., additional, Brouwer, Marianne L., additional, Hugen, Cindy A.C., additional, Niers, Laetitia E.M., additional, Sprij, Arwen J., additional, Rikkers-Mutsaerts, Eleonora R.V.M., additional, Rottier, Bart L., additional, Verhaak, Chris M., additional, Pijnenburg, Mariëlle W., additional, and Merkus, Peter J.F.M., additional

Published
2017
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38. The virtual asthma clinic: Description and analysis of website-use

Author

van den Wijngaart, Lara, primary, Geldtmeijer, Judith, additional, Roukema, Jolt, additional, Boehmer, Annemie, additional, Brouwer, Marianne, additional, Hugen, Cindy, additional, Niers, Titia, additional, Sprij, Arwen, additional, Rikkers-Mutsaerts, Noor, additional, Rottier, Bart, additional, Verhaak, Chris, additional, Pijnenburg, Marielle, additional, and Merkus, Peter, additional

Published
2016
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42. The effect of 3% and 6% hypertonic saline in viral bronchiolitis: a randomised controlled trial

Author

Teunissen, Jasmijn, primary, Hochs, Anne H.J., additional, Vaessen-Verberne, Anja, additional, Boehmer, Annemie L.M., additional, Smeets, Carien C.J.M., additional, Brackel, Hein, additional, van Gent, René, additional, Wesseling, Judith, additional, Logtens-Stevens, Danielle, additional, de Moor, Ronald, additional, Rosias, Philippe P.R., additional, Potgieter, Steph, additional, Faber, Marianne R., additional, Hendriks, Han J.E., additional, Janssen-Heijnen, Maryska L.G., additional, and Loza, Bettina F., additional

Published
2014
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48. 17 Bèta-hydroxysteroid dehydrogenase-3 deficiency: diagnosis, pheontypic variability, population genetics, and worldwide distribution of ancient and de novo mutations

Author

Boehmer, Annemie, Brinkmann, Albert, Ayuningtyas, Wireni, Halley, Dicky, Niermeijer, Martinus, Andersson, S, Jong, Frank, Kayserili, H, de Vroede, MA, Otten, BJ, Rouwé, CW, Mendonça, BB, Rodrigues, C, Bode, HH, Ruiter, Petra, Delemarre - van de Waal, H, Drop, Sten, Pediatrics, Developmental Biology, Epidemiology, and Clinical Genetics

Published
1999

50. AS01 How salty may it be? Effect of inhaled hypertonic saline solution to treat infants hospitalized with viral bronchiolitis

Author

Teunissen, Jasmijn, primary, Hochs, Anne, additional, Vaessen-Verberne, Anja, additional, Boehmer, Annemie, additional, Smeets, Carien, additional, Brackel, Hein, additional, van Gent, Rene, additional, Wesseling, Judith, additional, de Moor, Ronald, additional, Rosias, Philippe, additional, Potgieter, Steven, additional, Droog, Richard, additional, Hendriks, Han, additional, Logtens-Stevens, Danielle, additional, Janssen-Heijnen, Mariska, additional, and Loza, Bettina, additional

Published
2011
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