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445 results on '"Boehm, Andreas"'

1. The european organisation for research and treatment of cancer head and neck cancer module (EORTC QLQ-HN43): Estimates for minimal important difference and minimal important change

Author

Singer, Susanne, Hammerlid, Eva, Tomaszewska, Iwona M., Amdal, Cecilie D., Herlofson, Bente B., Santos, Marcos, Castro Silva, Joaquim, Mehanna, Hisham, Fullerton, Amy, Young, Teresa, Fernandez Gonzalez, Loreto, Inhestern, Johanna, Pinto, Monica, Arraras, Juan I., Yarom, Noam, Bonomo, Pierluigi, Baumann, Ingo, Galalae, Razvan, Nicolatou-Galitis, Ourania, Kiyota, Naomi, Raber-Durlacher, Judith, Salem, Dina, Fabian, Alexander, Boehm, Andreas, Krejovic-Trivic, Sanja, Chie, Wei-Chu, Taylor, Katherine J., Sherman, Allen C., Licitra, Lisa, Machiels, Jean-Pascal, and Bjordal, Kristin

Published
2024
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7. Methodological approach for determining the Minimal Important Difference and Minimal Important Change scores for the European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module (EORTC QLQ-HN43) exemplified by the Swallowing scale

Author

Singer, Susanne, Hammerlid, Eva, Tomaszewska, Iwona M., Amdal, Cecilie Delphin, Bjordal, Kristin, Herlofson, Bente Brokstad, Santos, Marcos, Silva, Joaquim Castro, Mehanna, Hisham, Fullerton, Amy, Brannan, Christine, Gonzalez, Loreto Fernandez, Inhestern, Johanna, Pinto, Monica, Arraras, Juan I., Yarom, Noam, Bonomo, Pierluigi, Baumann, Ingo, Galalae, Razvan, Nicolatou-Galitis, Ourania, Kiyota, Naomi, Raber-Durlacher, Judith, Salem, Dina, Fabian, Alexander, Boehm, Andreas, Krejovic-Trivic, Sanja, Chie, Wei-Chu, Taylor, Katherine, Simon, Christian, Licitra, Lisa, and Sherman, Allen C.

Published
2022
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14. Long‐term health‐related quality of life in head and neck cancer survivors: A large multinational study.

Author

Taylor, Katherine J., Amdal, Cecilie D., Bjordal, Kristin, Astrup, Guro L., Herlofson, Bente B., Duprez, Fréderic, Gama, Ricardo R., Jacinto, Alexandre, Hammerlid, Eva, Scricciolo, Melissa, Jansen, Femke, Verdonck‐de Leeuw, Irma M., Fanetti, Giuseppe, Guntinas‐Lichius, Orlando, Inhestern, Johanna, Dragan, Tatiana, Fabian, Alexander, Boehm, Andreas, Wöhner, Ulrike, and Kiyota, Naomi

Subjects
HEAD & neck cancer, QUALITY of life, CANCER survivors, NECK dissection, COMBINED modality therapy
Abstract

Head and neck cancer (HNC) patients suffer from a range of health‐related quality of life (HRQoL) issues, but little is known about their long‐term HRQoL. This study explored associations between treatment group and HRQoL at least 5 years' post‐diagnosis in HNC survivors. In an international cross‐sectional study, HNC survivors completed the European Organization for Research and Treatment of Cancer (EORTC) quality of life core questionnaire (EORTC‐QLQ‐C30) and its HNC module (EORTC‐QLQ‐H&N35). Meaningful HRQoL differences were examined between five treatment groups: (a) surgery, (b) radiotherapy, (c) chemo‐radiotherapy, (d) radiotherapy ± chemotherapy and neck dissection and (e) any other surgery (meaning any tumour surgery that is not a neck dissection) and radiotherapy ± chemotherapy. Twenty‐six sites in 11 countries enrolled 1105 survivors. They had a median time since diagnosis of 8 years, a mean age of 66 years and 71% were male. After adjusting for age, sex, tumour site and UICC stage, there was evidence for meaningful differences (10 points or more) in HRQoL between treatment groups in seven domains (Fatigue, Mouth Pain, Swallowing, Senses, Opening Mouth, Dry Mouth and Sticky Saliva). Survivors who had single‐modality treatment had better or equal HRQoL in every domain compared to survivors with multimodal treatment, with the largest differences for Dry Mouth and Sticky Saliva. For Global Quality of Life, Physical and Social Functioning, Constipation, Dyspnoea and Financial Difficulties, at least some treatment groups had better outcomes compared to a general population. Our data suggest that multimodal treatment is associated with worse HRQoL in the long‐term compared to single modality. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Induction chemotherapy followed by radiotherapy for larynx preservation in advanced laryngeal and hypopharyngeal cancer: Outcome prediction after one cycle induction chemotherapy by a score based on clinical evaluation, computed tomography-based volumetry and 18F-FDG-PET/CT

Author

Wichmann, Gunnar, Krüger, Anne, Boehm, Andreas, Kolb, Marlen, Hofer, Mathias, Fischer, Milos, Müller, Stefan, Purz, Sandra, Stumpp, Patrick, Sabri, Osama, Dietz, Andreas, and Kluge, Regine

Published
2017
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17. Synthesis of Antibiotics

Author

Kalesse, Markus, Böhm, Andreas, Kipper, Andi, Wandelt, Vanessa, Compans, Richard W, Series editor, Honjo, Tasuku, Series editor, Oldstone, Michael B. A., Series editor, Vogt, Peter K., Series editor, Malissen, Bernard, Series editor, Aktories, Klaus, Series editor, Kawaoka, Yoshihiro, Series editor, Rappuoli, Rino, Series editor, Galan, Jorge E., Series editor, Ahmed, Rafi, Series editor, Palme, Klaus, Series editor, Casadevall, Arturo, Series editor, Garcia-Sastre, Adolfo, Series editor, Stadler, Marc, editor, and Dersch, Petra, editor

Published
2016
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19. Serious Long-Term Effects of Head and Neck Cancer from the Survivors’ Point of View

Author

Taylor, Katherine J., Amdal, Cecilie, Bjordal, Kristin, Astrup, Guro, Herlofson, Bente, Duprez, Fréderic, Gama, Ricardo R., Jacinto, Alexandre, Hammerlid, Eva, Scricciolo, Melissa, Jansen, Femke, Verdonck-de Leeuw, Irma, Fanetti, Giuseppe, Guntinas-Lichius, Orlando, Inhestern, Johanna, Dragan, Tatiana, Fabian, Alexander, Boehm, Andreas, Wöhner, Ulrike, Kiyota, Naomi, Krüger, Maximilian, Bonomo, Pierluigi, Pinto, Monica, Nuyts, Sandra, Silva, Joaquim C., Stromberger, Carmen, Tramacere, Francesco, Bushnak, Ayman, Perotti, Pietro, Plath, Michaela, Paderno, Alberto, Stempler, Noa, Kouri, Maria, Singer, Susanne, Taylor, Katherine J., Amdal, Cecilie, Bjordal, Kristin, Astrup, Guro, Herlofson, Bente, Duprez, Fréderic, Gama, Ricardo R., Jacinto, Alexandre, Hammerlid, Eva, Scricciolo, Melissa, Jansen, Femke, Verdonck-de Leeuw, Irma, Fanetti, Giuseppe, Guntinas-Lichius, Orlando, Inhestern, Johanna, Dragan, Tatiana, Fabian, Alexander, Boehm, Andreas, Wöhner, Ulrike, Kiyota, Naomi, Krüger, Maximilian, Bonomo, Pierluigi, Pinto, Monica, Nuyts, Sandra, Silva, Joaquim C., Stromberger, Carmen, Tramacere, Francesco, Bushnak, Ayman, Perotti, Pietro, Plath, Michaela, Paderno, Alberto, Stempler, Noa, Kouri, Maria, and Singer, Susanne

Abstract

The long-term problems of head and neck cancer survivors (HNCS) are not well known. In a cross-sectional international study aimed at exploring the long-term quality of life in this population, 1114 HNCS were asked to state their two most serious long-term effects. A clinician recorded the responses during face-to-face appointments. A list of 15 example problems was provided, but a free text field was also available. A total of 1033 survivors responded to the question. The most frequent problems were ‘dry mouth’ (DM) (n = 476; 46%), ‘difficulty swallowing/eating’ (DSE) (n = 408; 40%), ‘hoarseness/difficulty speaking’ (HDS) (n = 169; 16%), and ‘pain in the head and neck’ (PHN) (n = 142; 14%). A total of 5% reported no problems. Logistic regression adjusted for age, gender, treatment, and tumor stage and site showed increased odds of reporting DM and DSE for chemo-radiotherapy (CRT) alone compared to surgery alone (odds ratio (OR): 4.7, 95% confidence interval (CI): 2.5–9.0; OR: 2.1, CI: 1.1–3.9), but decreased odds for HDS and PHN (OR: 0.3, CI: 0.1–0.6; OR: 0.2, CI: 0.1–0.5). Survivors with UICC stage IV at diagnosis compared to stage I had increased odds of reporting HDS (OR: 1.9, CI: 1.2–3.0). Laryngeal cancer survivors had reduced odds compared to oropharynx cancer survivors of reporting DM (OR: 0.4, CI: 0.3–0.6) but increased odds of HDS (OR: 7.2, CI: 4.3–12.3). This study provides evidence of the serious long-term problems among HNCS., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2023

20. High-Dose Glucocorticoids for the Treatment of Sudden Hearing Loss.

Author

Plontke, Stefan K., Girndt, Matthias, Meisner, Christoph, Fischer, Imma, Böselt, Iris, Löhler, Jan, Ludwig-Kraus, Beatrice, Richter, Michael, Steighardt, Jörg, Reuter, Bernd, Böttcher, Christoph, Langer, Jörg, Pethe, Wolfram, Seiwerth, Ingmar, Jovanovic, Nebojsa, Großmann, Wilma, Kienle-Gogolok, Andrea, Boehm, Andreas, Neudert, Marcus, and Diensthuber, Marc

Subjects
GLUCOCORTICOIDS, SPEECH perception, TINNITUS, HYPERTENSION, PREDNISOLONE, INTRAVENOUS therapy, CONFIDENCE intervals, ANALYSIS of variance, DEXAMETHASONE, COMMUNICATIVE competence, SENSORINEURAL hearing loss, TREATMENT effectiveness, RANDOMIZED controlled trials, QUALITY of life, DESCRIPTIVE statistics, STATISTICAL sampling, DRUG side effects, INSULIN resistance
Abstract

Background: Systemic glucocorticoids are commonly used for primary therapy of idiopathic sudden sensorineural hearing loss (ISSNHL). However, the comparative effectiveness and risk profiles of high-dose over lower-dose regimens remain unknown. Methods: We randomly assigned patients with sudden hearing loss of greater than or equal to 50 dB within 7 days from onset to receive either 5 days of high-dose intravenous prednisolone at 250 mg/d (HD-Pred), 5 days of high-dose oral dexamethasone at 40 mg/d (HD-Dex), or, as a control, 5 days of oral prednisolone (Pred-Control) at 60 mg/d followed by 5 days of tapering doses. The primary outcome was the change in hearing threshold (pure tone average) in the three most affected contiguous frequencies from baseline to day 30. Secondary outcomes included speech understanding, tinnitus, communication competence, quality of life, hypertension, and insulin resistance. Results: A total of 325 patients were randomly assigned. Mean change in 3PTAmost affected hearing threshold from baseline to 30 days was 34.2 dB (95% CI, 28.4 to 40.0) in the HD-Pred group, 41.4 dB (95% CI, 35.6 to 47.2) in the HD-Dex group, and 41.0 dB (95% CI, 35.2 to 46.8) in the Pred-Control group (P=0.09 for analysis of variance). There were more adverse events related to trial medication in the HD-Pred (n=73) and HD-Dex (n=76) groups than in the Pred-Control group (n=46). Conclusions: Systemic high-dose glucocorticoid therapy was not superior to a lower-dose regimen in patients with ISSNHL, and it was associated with a higher risk of side effects. (Funded by the Federal Ministry of Education and Research [BMBF]; EudraCT number, 2015-002602-36.) [ABSTRACT FROM AUTHOR]

Published
2024
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23. Serious Long-Term Effects of Head and Neck Cancer from the Survivors’ Point of View

Author

Taylor, Katherine J., primary, Amdal, Cecilie D., additional, Bjordal, Kristin, additional, Astrup, Guro L., additional, Herlofson, Bente B., additional, Duprez, Fréderic, additional, Gama, Ricardo R., additional, Jacinto, Alexandre, additional, Hammerlid, Eva, additional, Scricciolo, Melissa, additional, Jansen, Femke, additional, Verdonck-de Leeuw, Irma M., additional, Fanetti, Giuseppe, additional, Guntinas-Lichius, Orlando, additional, Inhestern, Johanna, additional, Dragan, Tatiana, additional, Fabian, Alexander, additional, Boehm, Andreas, additional, Wöhner, Ulrike, additional, Kiyota, Naomi, additional, Krüger, Maximilian, additional, Bonomo, Pierluigi, additional, Pinto, Monica, additional, Nuyts, Sandra, additional, Silva, Joaquim C., additional, Stromberger, Carmen, additional, Tramacere, Francesco, additional, Bushnak, Ayman, additional, Perotti, Pietro, additional, Plath, Michaela, additional, Paderno, Alberto, additional, Stempler, Noa, additional, Kouri, Maria, additional, and Singer, Susanne, additional

Published
2023
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26. The Tumor Therapy Manager – Design, Refinement and Clinical Use of a Software Product for ENT Surgery Planning and Documentation

Author

Rössling, Ivo, Dornheim, Jana, Dornheim, Lars, Boehm, Andreas, Preim, Bernhard, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, Taylor, Russell H., editor, and Yang, Guang-Zhong, editor

Published
2011
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27. JSquash: Source Code Analysis of Embedded Database Applications for Determining Sql Statements

Author

Seipel, Dietmar, Boehm, Andreas M., Fröhlich, Markus, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, Goebel, Randy, editor, Siekmann, Jörg, editor, Wahlster, Wolfgang, editor, Abreu, Salvador, editor, and Seipel, Dietmar, editor

Published
2011
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30. Squash: A Tool for Analyzing, Tuning and Refactoring Relational Database Applications

Author

Boehm, Andreas M., Seipel, Dietmar, Sickmann, Albert, Wetzka, Matthias, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Goebel, Randy, editor, Siekmann, Jörg, editor, Wahlster, Wolfgang, editor, Seipel, Dietmar, editor, Hanus, Michael, editor, and Wolf, Armin, editor

Published
2009
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42. Teleseminare über ISDN-basierte Videokonferenzsysteme

Author

Böhm, Andreas, Huwer, Matthias, Oberndorfer, Wolfgang, Schmitz, Roland, Uellner, Stefan, Gawron, Wolf-Rüdiger, editor, Riedewald, Günter, editor, Jaus, Eckhard, editor, Dürre, Roland, editor, Herrmann, Thomas, editor, and Just-Hahn, Katharina, editor

Published
1998
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46. Report on the Annual Meeting of the Working Group "Mycology"

Author

Heupel, Monika, Kretschmer, Matthias, Wiwiorra, Melanie, Schröder, Matthias, Böhm, Andreas, Leroch, Michaela, Hahn, Matthias, Rabenstein, Frank, Rohde, Silke, Haase, Anita, Rohrig, Karina, Voß, Hans-Henning, Winterberg, Britta, Schirawski, Jan, Linne, Uwe, Leßing, Franziska, Eichhorn, Heiko, and Kahmann, Regine

Published
2007

48. Report on the Annual Meeting of the Working Group 'Host-Parasite Interactions'

Author

Conrath, Uwe, Mönchmeier, Claudia, Knogge, Wolfgang, Dahal, Diwakar, Braun, Hans-Peter, Wydra, Kerstin, Ghareeb, Hassan, Stahl, Frank, Boszo, Zoltan, Ott, Peter, Horbach, Ralf, Graf, Alexander, Thines, Eckhard, Deising, Holger B., Priyadarshini, Indira, Hensel, Goetz, Kumlehn, Jochen, Imani, Jafargholi, Hueckelhoven, Ralph, Zeier, Jürgen, Griebel, Thomas, Geuecke, Martina, Mishina, Tatiana, Masur, Clarissa, Jouanin, Lise, Schlaich, Nikolaus, Leroch, Michaela, Doehlemann, Gunther, Böhm, Andreas, Diwo, Janine, Mosbach, Andreas, Hahn, Matthias, Müller, Olaf, Kahmann, Regine, Schreier, Peter H., Uhrig, Joachim F., Münch, Steffen, Eichler, Nancy, Rahnamaeian, Mohammad, Altincicek, Boran, Kogel, Karl-Heinz, Langen, Gregor, Stein, Elke, Vilcinskas, Andreas, Schirawski, Jan, Brefort, Thomas, Schipper, Kerstin, Münch, Karin, Schöning, Julia, Mannhaupt, Gertrud, Schacht, Tanja, Unger, Christoph, Zellerhoff, Nina, Schweizer, Patrick, Crous, Pedro W., Groenewald, Johannes Z., and Schaffrath, Ulrich

Published
2007

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