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46 results on '"Bodemann, H."'

1. Freie Vorträge

Author

v. Scheel, J., Kastenbauer, E. R., Pau, H. W., Straehler-Pohl, H.-J., Stiens, R., Fiebach, A., Plath, P., Mann, W., Beck, Chl., Arnold, H., Bodemann, H., Bumb, P., Wagner, R., Mika, H., Wissen-Siegert, I., Wilhelm, H.-J., Dietz, R., Schmieder, A., Gülzow, J., Schröder, M., Stennert, E., von Heyden, H. W., Scherpe, A., Beyer, H.-J., Kastenbauer, E. R., editor, and Lehnhardt, Ernst, editor

Published
1983
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2. Hämatologie II

Author

Meusers, P., Heidemann, H., Lunscken, C., Uppenkamp, M., Zou, P., Brittinger, G., Hinterberger, W., Bettelheim, P., Fischer, M., Lechner, K., Neumann, E., Geißler, K., Niessner, H., Höcker, P., Deutsch, E., Bodemann, H. H., Schröter-Urban, H., Tanzi-Fetta, R. F., Löhr, G. W., Andreesen, R., Osterholz, J., Bross, K. J., Porzsolt, F., Stötter, H., Pindur, G., Seifried, D., Rasche, H., Miehlke, Klaus, editor, and Bergmann, J. F.

Published
1984
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3. Hämatologie/Onkologie

Author

Bodemann, H. H., Rieger, A., Schröter-Urban, H., Volk, B. A., Bross, K., Gerok, W., Löhr, G. W., Heilmann, E., Ridderskamp, P., Baumgart, P., Winkelmann, M., Schmitz, G., Aul, C., Scharf, R. E., Pfitzer, P., Schneider, W., Heisig, S., Hinterberger, W., Gadner, H., Höcker, P., Neumann, E., Schmidmeier, W., Bettelheim, P., Lechner, K., Deutsch, E., Arnold, R., Carbonell, F., Fliedner, T. M., Friedrich, W., Goldmann, S. F., Heimpel, H., Heit, W., Kleihauer, E., Kohne, E., Kubanek, B., Kurrle, E., Lohrmann, H. P., Pflieger, H., Schmeiser, T., Fritz, E., Radaszkiewicz, T., Dorda, W., Ludwig, H., Weh, H. J., Kuse, R., Hausmann, K., Hossfeld, D. K., Gerecke, D., Kreß, M., Gross, R., Heinz, R., Aiginger, P., Pont, J., Schüller, J., Walcher, G., Hanak, H., Sinn, E., Wirth, M., Dittrich, Ch., Schwarzmeier, J., Kühböck, J., Honetz, N., Alth, G., Stacher, A., Bartels, H., Lennert, K., Köttgen, E., Schölmerich, J., Rühle, K. H., Heim, M. E., Bojar, H., Saeger, H., Queißer, W., Schick, E., Frey, H. O., Holm, E., Luster, W., Gropp, C., Havemann, K., Hehlmann, R., Schreiber, A. M., Kreeb, G., Luz, A., Mesa-Tejada, R., Lohe, J. K., Prechtel, K., Schalhorn, A., Sauer, H., Wilmanns, W., Stupp-Poutot, G., Schuchhardt, C., Fiebig, H. H., Henß, H., Koch, H., Heinrich, E., Labedzki, L., Hartlapp, H. J., WeiBbach, L., von Heyden, H. W., Hansen, D., Nagel, G. A., Hoffmann, H., Schneider, B., Hinterberger, R., Fischer, J., Preiß, J., Weigand, H., Brückner, R., Schreml, W., Hügl, W., Koßmann, B., Manegold, C., Abel, U., Fritze, D., Herrmann, R., Niederle, N., Kurschel, E., Schmidt, C. G., Schnitzler, G., König, H. J., Katz, R., Trux, F. A., Bloch, R., Keymling, M., Wolkewitz, K. D., Fritsch, H., Hanisch, I., Brumen, L., Edler, L., Hartlapp, J. H., Schmidt, R. E., Illiger, J. H., Krieger, D., Hoelzer, D., and Schlegel, Bernhard, editor

Published
1983
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4. Hämatologie/Onkologie

Author

Hinterberger, W., Bettelheim, P., Haubenstock, A., Homan, R., Neumann, E., Hiddemann, W., Wörmann, B., Ritter, J., Schellong, G., Riehm, H., Henze, G., Langermann, H.-J., Kaufmann, U., Engelhard, M., Brittinger, G., Havemann, K., Gramse, M., Gassel, W.-D., Ho, A. D., Brandeis, W., Pfreundschuh, M., Hunstein, W., Shüning, F., Schaefer, U. W., Shmidt, C. G., Beyer, J. P., Nowrousian, M. R., Öhl, S., Rüther, U., Scheulen, M., Wetter, O., Bamberg, M., Scherer, E., Schmitt, G., Haralambie, E., Linzenmeier, G., Grosse-Wilde, H., Kuwert, E., Henneberg, K., Luboldt, W., Leder, L. D., Richter, H.-J., Hantschke, D., Wolfrum, D. I., Mross, K., Mross, B., Nagel, G. A., Krieger, G., Kehl, A., Bause, J., Kneba, M., Nagel, G., Krapf, F., Renger, D., Schedel, I., Fricke, M., Kemper, A., Büchner, T., Deicher, H., Zimmermann, S., Felber, D., Liebert, A., Jensen, H. L., Walzel, H., Habets, L., Spoerl, D., Mussgnug, G., Westerhausen, M., Delbrück, H., Scharding, B., Meyer, W., Schwarze, G., Scheurlen, P. G., Fiebig, H. H., Henss, H., Schuchhardt, C., Löhr, G. W., Liesenfeld, A., Gropp, C., Gassel, W. D., Thomas, C., Seifert, W., Drings, P., Mahnke, H. G., Konrad, R. M., Wellens, W., Mitrou, P. S., Georgii, A., Diehl, V., Dudeck, J., Wetzel, W., Krüger, M., Dittrich, C., Rainer, H., Moser, K., Lenzhofer, R., Jakesz, R., Reiner, G., Kolb, R., Schmemper, M., Micksche, M., Bruntsch, U., Edler, L., Gallmeier, W. M., Kaufmann, M., Mayr, A. C., Queißer, W., Jungi, F., Senn, H.-J., Hartlapp, J. H., Peiss, J., Vaupel, H. A., Illiger, H. J., Becher, R., Firusian, N., Aiginger, P., Schwarz, H. P., Zahler, J., Kuzmits, R., Kühböck, J., Krisch, J., Mayr, W. R., Schemper, M., Spona, J., Scheulen, M. E., Bremer, K., Niederle, N., Krischke, W., Higi, M., Seeber, S., Schmidt, C. G., Höffken, K., Ippisch, A., Lohmann, R., Pfeiffer, R., Bodemann, H. H., Rieger, A., Wiedenmann, B., Elbaum, D., Graubner, M., Pralle, H., Löffler, H., Mueller-Eckhardt, C., Bergmann, L., Heusermann, U., Altmeyer, P., Stutte, H. J., Anger, G., Malberg, K., Wutke, K., and Schlegel, Bernhard, editor

Published
1982
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13. Freie Vorträge

Author

Scheel, J., primary, Kastenbauer, E. R., additional, Pau, H. W., additional, Straehler-Pohl, H.-J., additional, Stiens, R., additional, Fiebach, A., additional, Plath, P., additional, Mann, W., additional, Beck, Chl., additional, Arnold, H., additional, Bodemann, H., additional, Bumb, P., additional, Wagner, R., additional, Mika, H., additional, Wissen-Siegert, I., additional, Wilhelm, H.-J., additional, Dietz, R., additional, Schmieder, A., additional, Gülzow, J., additional, Schröder, M., additional, Stennert, E., additional, Heyden, H. W., additional, Scherpe, A., additional, and Beyer, H.-J., additional

Published
1983
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20. Potassium and sodium concentrations in the erythrocytes of newborn infants and adults

Author

Schröter W and Bodemann H

Subjects
chemistry, business.industry, Potassium, Sodium, Pediatrics, Perinatology and Child Health, chemistry.chemical_element, Medicine, business, Molecular biology
Abstract

Es besteht kein sicherer Unterschied zwischen dem Natrium- und Kaliumgehalt von Neugeborenen- und Erwachsenenerythrocyten. Der absolute Gehalt der Erythrocyten an Kationen hangt weitgehend von der Vorbehandlung der Zellen und von der Mesmethodik ab. Am geeignetsten fur Studien uber die Permeabilitat der Erythrocytenmembran fur Kationen ist die hier angewandte flammenphotometrische Bestimmung im Erythrocytenbrei nach Waschen der Zellen mit Cholinchlorid. Die mit dieser Methode bestimmten Kationenkonzentrationen sind relativ niedrig. Die Natriumkonzentrationen stimmen gut mit Ergebnissen anderer Autoren uberein, die nach Korrektur des Plasmafaktors gewonnen wurden.

Published
1969

21. Comparison of the side-dependent effects of Na and K on orthophosphate-, UTP-, and ATP-promoted ouabain binding to reconstituted human red blood cell ghosts.

Author

Bodemann, H H and Hoffman, J F

Abstract

This paper is concerned with analyzing the sidedness of action of various determinants which alter the rate of ouabain binding to human red blood cell ghosts. Thus, ouabain binding promoted by orthophosphate (Pi) and its inhibition by Na are shown to be due to inside Pi and inside Na. External K inhibits Pi-promoted ouabain binding and Nao acts to decrease the effectiveness of Ko. Similarly, inside uridine triphosphate (UTPi) stimulates the rate of ouabain binding which can be antagonized by either Nai or Ko acting alone. The actions of Nai and Ko are different when ouabain binding is promoted by Pi and UTPi compared to inside adenosine triphosphate (ATPi). With ATPi, the ouabain binding rate is only affected when Nai and Ko are both present. Possible differences in the mechanism of action of K and Na on Pi-and UTP-promoted binding are discussed in the light of their sidedness of action.

Published
1976
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22. Side-dependent effects of internal versus external Na and K on ouabain binding to reconstituted human red blood cell ghosts.

Author

Bodemann, H H and Hoffman, J F

Abstract

The side-dependent effects of internal and external Na and K on the ouabain binding rate, as promoted by inside MgATP, has been evaluated utilizing reconstituted human red blood cell ghosts. Such ghost systems provide the situation where [Na]i, [K]i, [Na]o, and [K]o can each be varied under conditions in which the others are either absent or fixed at constant concentrations. It was found that, in the presence of Ko, increasing either [Na]i or [K]i resulted in decreasing the rate at which ouabain was bound. Changes in [Na]i or [K]i in the absence of Ko were without effect on the ouabain binding rate. Thus, the ouabain binding rate was found to vary inversely with the rate of Na:K and K:K exchange but was independent of the rate of Na:Na exchange. The effect of Ko in antagonizing ouabain binding, as well as the influence of Nao on this interaction, were found to require the presence of either Nai or Ki. The results are interpreted in terms of a model relating the availability of the ouabain binding site to different conformational states of the pump complex. Differences were observed in the ouabain binding properties of red cell ghosts compared to microsomal preparations but it is not known whether the basis for the differences resides in the different preparations studied or in the lack of control of sidedness in the microsomal systems.

Published
1976
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23. Effects of Mg and Ca on the side dependencies of Na and K on ouabain binding to red blood cell ghosts and the control of Na transport by internal Mg.

Author

Bodemann, H H and Hoffman, J F

Abstract

The effect of alteration in the concentration of internal Mg on the rate of ouabain binding to reconstituted human red blood cell ghosts has been evaluated as well as the effect of Mgi on Na:Na compared to Na:K exchange. It was found that the dependence of the rate of ATP-promoted ouabain binding on the combined presence of Nai and Ko which occurs at high [Mg]i is lost when the concentration of Mgi is lowered. The sensitivity of the external surface for Ko is also changed since Ko can now inhibit the ouabain binding rate in the absence of Nai; on the other hand Nao at low [Mg]i can stimulate ouabain binding indicating that the relative affinity of the outside surface for Nao has either increased or that for Ko has decreased or both. Thus the effects of changes in [Mg]i result in a change in the side-dependent actions of Na and K and emphasize the possible difficulties of interpreting results obtained on systems lacking sidedness. Mgi was found to be required for Pi-promoted ouabain binding and that the inhibitory action of Nai increased as [Mg]i was increased. In addition, Ca was found to be most effective in inhibiting the rate of ATP-promoted ouabain binding when Na and K were present together than when either was present alone. Na:K exchange was found to be more sensitive to the concentration of Mgi than Na:Na exchange; at low [Mg]i Na:K exchange could be stimulated without changing the extent of Na:Na exchange. These results are consistent with the idea that conformational states of the pump complex are directly influenced by [Mg]i.

Published
1976
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32. The red cell Na/K pump reaction cycle: ligand signal sites and Na coupled anion transport.

Author

Hoffman JF, Marín R, Bodemann HH, Callahan TJ, and Milanick M

Subjects
Animals, Biological Transport, Active physiology, Erythrocytes metabolism, Erythrocytes physiology, Humans, Sodium-Potassium-Exchanging ATPase chemistry, Anions pharmacokinetics, Erythrocytes enzymology, Ligands, Sodium pharmacokinetics, Sodium-Potassium-Exchanging ATPase physiology
Published
1991

33. [Therapy of small-cell bronchial carcinoma].

Author

Bodemann HH, Arnold H, Wannenmacher M, and Kraft A

Subjects
Antineoplastic Agents therapeutic use, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Brain Neoplasms radiotherapy, Brain Neoplasms secondary, Carcinoma, Bronchogenic radiotherapy, Carcinoma, Bronchogenic surgery, Carcinoma, Small Cell radiotherapy, Carcinoma, Small Cell surgery, Humans, Lung Neoplasms radiotherapy, Lung Neoplasms surgery, Prognosis, Radiotherapy Dosage, Time Factors, Carcinoma, Bronchogenic drug therapy, Carcinoma, Small Cell drug therapy, Lung Neoplasms drug therapy
Published
1984
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34. [Chemotherapy of metastatic nasopharyngeal cancer].

Author

Bodemann HH

Subjects
Antineoplastic Combined Chemotherapy Protocols therapeutic use, Humans, Lymphatic Metastasis, Nasopharyngeal Neoplasms drug therapy, Prognosis, Antineoplastic Agents therapeutic use, Nasopharyngeal Neoplasms secondary
Published
1984

35. Transfer of Tris buffer and effects on K+ loss in human red blood cells and reconstituted ghosts.

Author

Bodemann HH and Karsch B

Subjects
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid, 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid analogs & derivatives, 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid pharmacology, Bicarbonates pharmacology, Erythrocyte Membrane drug effects, Hemolysis, Humans, In Vitro Techniques, Osmolar Concentration, Time Factors, Erythrocytes drug effects, Potassium blood, Tromethamine pharmacology
Abstract

The rate of volume changes of human red blood cells in the presence of Tris-HCl is pH-dependent. At 37 degrees C, t 1/2 is 25-30 min at pH 7.4 and 10-20 min at pH 8.4. Hemolysis in Tris-HCl is delayed by H2DIDS but is promoted by low concentrations of bicarbonate. This bicarbonate effect has been reversed by inhibiting carbonic anhydrase with acetazolamide. K+ loss of red blood cells is increased at 37 degrees C in isotonic NaCl solutions containing in addition Tris-HCl. This Tris effect is enhanced from pH 6.4 to 8.4. At pH 8.4 K+ loss is stimulated about 3-fold by addition of 160 mM Tris-HCl. The onset of the Tris effect is delayed at pH 7.4 and below, but not at pH 8.4. Such a delay is absent after preincubation of the cells with Tris-HCl. After binding H2DIDS to red cells, no Tris-dependent increase of K+ loss has been observed. K+ loss of reconstituted red cell ghosts with equal internal and external chloride concentrations remained unaffected by Tris-HCl added to the external solution. In ghosts containing sucrose for isotonicity instead of choline chloride K+ loss is smaller but is stimulated by Tris-HCl approaching the rate in those ghosts with equal internal and external chloride concentrations. The transfer of Tris-HCl into red blood cells depends on the pH and on the chloride shift. As there is evidence that Tris-HCl raises the intracellular pH and reduces the Donnan potential at the membrane, K+ loss of red cells may be increased following an intracellular buffer interaction of hemoglobin and Tris-HCl.

Published
1984
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36. [The problem of the cellular receptor for cardiac glycosides (author's transl)].

Author

Bodemann HH

Subjects
Electrolytes blood, Erythrocyte Membrane drug effects, Humans, Myocardial Contraction drug effects, Sodium-Potassium-Exchanging ATPase antagonists & inhibitors, Stimulation, Chemical, Cardiac Glycosides metabolism, Erythrocyte Membrane enzymology, Erythrocytes enzymology, Receptors, Drug metabolism
Abstract

This review concerns the Na+, K+ -ATPase as well as the Na+, K+ -pump in the intact membrane and the highly specific inhibition of this transport system by cardiac glycosides. The interaction between glycoside and enzyme and the regulation of the kinetics of glycoside binding by ATP, K+, Na+, Mg2+ and Ca2+ are described. Emphasis is placed on the significance of the Na+, K+ -pump as the pharmacological receptor for cardiac glycosides. The problem encountered and progress made in attempting to correlate the inotropic action of cardiac glycosides with the binding of these drugs to the heart muscle and with the inhibition of the Na+, K+ -pump are reported. Recent results concerning increases of the intracellular Na+ concentration which are obtained by a partial inhibition of the Na+, K+ -pump and which are followed by an elevation of the intracellular Ca2+ -activity are reviewed. The discovery of a digitalis-like endogenous activity corresponds to the high specificity of the receptor for cardiac glycosides.

Published
1981
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40. [Prevention and therapy of tick encephalitis].

Author

Bodemann H and Schmitz H

Subjects
Bed Rest, Encephalitis, Tick-Borne drug therapy, Encephalitis, Tick-Borne prevention & control, Germany, West, Humans, Immunoglobulins therapeutic use, Vaccination, Encephalitis, Tick-Borne therapy
Published
1978
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41. [Staging and study procedure in small-cell bronchial carcinoma].

Author

Bodemann HH, Arnold H, Wannenmacher M, and Kraft A

Subjects
Carcinoma, Bronchogenic classification, Carcinoma, Small Cell classification, Humans, Lung Neoplasms classification, Methods, Neoplasm Metastasis, Neoplasm Staging, Carcinoma, Bronchogenic pathology, Carcinoma, Small Cell pathology, Lung Neoplasms pathology
Published
1984
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42. [Neo-adjuvant chemotherapy of head and neck cancer].

Author

Bodemann H, Arnold H, Mann W, Hannich S, Kraft A, and Löhr GW

Subjects
Adult, Aged, Bleomycin administration & dosage, Carcinoma, Squamous Cell drug therapy, Carcinoma, Squamous Cell surgery, Combined Modality Therapy, Female, Head and Neck Neoplasms surgery, Humans, Male, Methotrexate administration & dosage, Middle Aged, Mouth Neoplasms drug therapy, Mouth Neoplasms surgery, Prognosis, Vincristine administration & dosage, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Head and Neck Neoplasms drug therapy
Abstract

Pre-operative chemotherapy with vincristine, moderately high doses of methotrexate plus "rescue", and bleomycin for six weeks was administered to 26 patients with untreated carcinoma of the head and neck. Treatment was well tolerated and compliance was very good. Objective side effects necessitated ending treatment in ten patients. Tumour regression of over 50% (responders with partial or complete remission) was recorded in 17 patients; five of them had no histological evidence of tumour in the surgical specimen. In three patients the tumour regressed slightly, in two it remained unchanged and in four it had progressed at the end of treatment (nine non-responders). After a minimum observation period of 36 months 12 of the 26 patients were still alive. Median survival time had not yet been reached in the 17 responders. But the median survival time of the non-responders was 15 months. It is concluded that this form of treatment is very effective and well tolerated. If response is achieved it opens the prospect of prolonged survival time.

Published
1986
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43. [Severe and prognostically unfavourable forms of tick-borne encephalitis (early-summer meningo-encephalitis) in Freiburg (author's transl)].

Author

Bodemann H, Hoppe-Seyler P, Blum H, and Herkel L

Subjects
Adult, Coma etiology, Encephalitis, Tick-Borne complications, Female, Germany, West, Humans, Male, Middle Aged, Paralysis etiology, Pneumonia complications, Prognosis, Quadriplegia etiology, Time Factors, Encephalitis, Tick-Borne diagnosis
Abstract

Eight patients with proven tick-borne encephalitis (early-summer meningo-encephalitis; central European encephalitis) were treated in 1979. The disease ran a severe course in four: one died after six weeks of coma and pneumonia with right-heart failure. Another patient is in coma for more than 40 weeks. A third patient had severe flaccid tetraplegia more than 10 weeks after initial coma. The fourth patient still had leg paresis after nine weeks, her left arm also being largely paralysed. This high incidence of severe forms of the disease differs from other published reports.

Published
1980
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