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8 results on '"Bochkova, Zhanna V."'

1. Redox differences between rat neonatal and adult cardiomyocytes under hypoxia

Author

Ivanova, Alexandra D., Kotova, Daria A., Khramova, Yulia V., Morozova, Ksenia I., Serebryanaya, Daria V., Bochkova, Zhanna V., Sergeeva, Anastasia D., Panova, Anastasiya S., Katrukha, Ivan A., Moshchenko, Aleksandr A., Oleinikov, Vladimir A., Semyanov, Alexey V., Belousov, Vsevolod V., Katrukha, Alexey G., Brazhe, Nadezda A., and Bilan, Dmitry S.

Published
2024
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3. SERS uncovers the link between conformation of cytochrome c heme and mitochondrial membrane potential

Author

Brazhe, Nadezda A., primary, Nikelshparg, Evelina I., additional, Baizhumanov, Adil A., additional, Grivennikova, Vera G., additional, Semenova, Anna A., additional, Novikov, Sergey M., additional, Volkov, Valentyn S., additional, Arsenin, Aleksey V., additional, Yakubovsky, Dmitry I., additional, Evlyukhin, Andrey B., additional, Bochkova, Zhanna V., additional, Goodilin, Eugene A., additional, Maksimov, Georgy V., additional, Sosnovtseva, Olga, additional, and Rubin, Andrey B., additional

Published
2023
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4. Multiple Mutations in the Non-Ordered Red Ω-Loop Enhance the Membrane-Permeabilizing and Peroxidase-like Activity of Cytochrome c

Author

Chertkova, Rita V., primary, Firsov, Alexander M., additional, Brazhe, Nadezda A., additional, Nikelshparg, Evelina I., additional, Bochkova, Zhanna V., additional, Bryantseva, Tatyana V., additional, Semenova, Marina A., additional, Baizhumanov, Adil A., additional, Kotova, Elena A., additional, Kirpichnikov, Mikhail P., additional, Maksimov, Georgy V., additional, Antonenko, Yuriy N., additional, and Dolgikh, Dmitry A., additional

Published
2022
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5. Detection of Hypertension-Induced Changes in Erythrocytes by SERS Nanosensors

Author

Nikelshparg, Evelina I., Baizhumanov, Adil A., Bochkova, Zhanna V., Novikov, Sergey M., Yakubovsky, Dmitry I., Arsenin, Aleksey V., Volkov, Valentyn S., Goodilin, Eugene A., Semenova, Anna A., Sosnovtseva, Olga, Maksimov, Georgy V., Brazhe, Nadezda A., Nikelshparg, Evelina I., Baizhumanov, Adil A., Bochkova, Zhanna V., Novikov, Sergey M., Yakubovsky, Dmitry I., Arsenin, Aleksey V., Volkov, Valentyn S., Goodilin, Eugene A., Semenova, Anna A., Sosnovtseva, Olga, Maksimov, Georgy V., and Brazhe, Nadezda A.

Abstract

Surface-enhanced Raman spectroscopy (SERS) is a promising tool that can be used in the detection of molecular changes triggered by disease development. Cardiovascular diseases (CVDs) are caused by multiple pathologies originating at the cellular level. The identification of these deteriorations can provide a better understanding of CVD mechanisms, and the monitoring of the identified molecular changes can be employed in the development of novel biosensor tools for early diagnostics. We applied plasmonic SERS nanosensors to assess changes in the properties of erythrocytes under normotensive and hypertensive conditions in the animal model. We found that spontaneous hypertension in rats leads (i) to a decrease in the erythrocyte plasma membrane fluidity and (ii) to a decrease in the mobility of the heme of the membrane-bound hemoglobin. We identified SERS parameters that can be used to detect pathological changes in the plasma membrane and submembrane region of erythrocytes.

Published
2022

6. Detection of Hypertension-Induced Changes in Erythrocytes by SERS Nanosensors

Author

Nikelshparg, Evelina I., primary, Baizhumanov, Adil A., additional, Bochkova, Zhanna V., additional, Novikov, Sergey M., additional, Yakubovsky, Dmitry I., additional, Arsenin, Aleksey V., additional, Volkov, Valentyn S., additional, Goodilin, Eugene A., additional, Semenova, Anna A., additional, Sosnovtseva, Olga, additional, Maksimov, Georgy V., additional, and Brazhe, Nadezda A., additional

Published
2022
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7. Cytochrome C heme conformation is sensitive to membrane potential in isolated mitochondria as revealed by SERS

Author

Nikelshparg, Evelina I., Bayzhumanov, Adil A., Bochkova, Zhanna V., Grivennikova, Vera G., Semenova, Anna A., Goodilin, Evgeny A., Novikov, Sergey M., Sosnovtseva, Olga, Maksimov, Georgy V., Brazhe, Nadezda A., Nikelshparg, Evelina I., Bayzhumanov, Adil A., Bochkova, Zhanna V., Grivennikova, Vera G., Semenova, Anna A., Goodilin, Evgeny A., Novikov, Sergey M., Sosnovtseva, Olga, Maksimov, Georgy V., and Brazhe, Nadezda A.

Published
2021

8. SERS uncovers the link between conformation of cytochrome c heme and mitochondrial membrane potential

Author

Brazhe, Nadezda A., primary, Nikelshparg, Evelina I., additional, Baizhumanov, Adil A., additional, Grivennikova, Vera G., additional, Semenova, Anna A., additional, Novikov, Sergey M., additional, Volkov, Valentyn S., additional, Arsenin, Aleksey V, additional, Yakubovsky, Dmitry I., additional, Evlyukhin, Andrey B., additional, Bochkova, Zhanna V., additional, Goodilin, Eugene A., additional, Maksimov, Georgy V., additional, Sosnovtseva, Olga, additional, and Rubin, Andrey B., additional

Published
2021
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