Search

Your search keyword '"Bo-Ning Liu"' showing total 5 results
Start Over Author "Bo-Ning Liu"
5 results on '"Bo-Ning Liu"'

1. Plerixafor-based mobilization and mononuclear cell counts in graft increased the risk of engraftment syndrome after autologous hematopoietic stem cell transplantation

Author

Le-Qing Cao, Qi Wen, Bo-Ning Liu, Zhen-Yu Zhao, Xiao-Hui Zhang, Lan-Ping Xu, Huan Chen, Yu Wang, Lu Yu, Feng-Rong Wang, Xiao-Jun Huang, and Xiao-Dong Mo

Subjects
Diseases of the blood and blood-forming organs, RC633-647.5
Abstract

Engraftment syndrome (ES) is one of the most common complications in the early phase after autologous hematopoietic stem cell transplantation (ASCT), and we aimed to evaluate the incidence and risk factors for ES patients receiving ASCT in the era of plerixafor-based mobilization. A total of 294 were enrolled, and 16.0% (n = 47) experienced ES after ASCT. The main clinical manifestations were fever (100%), diarrhea (78.7%), skin rash (23.4%), and hypoxemia/pulmonary edema (12.8%). Plerixafor-based mobilization was associated with higher counts of CD3+ cells, CD4+ cells, and CD8+ cells in grafts. In univariate analysis of the total cohort, age ≥60 years, receiving ASCT at complete remission (CR), higher number of mononuclear cell (MNC), CD3+ cell counts, CD4+ cells as well as CD8+ cells transfused and plerixafor-based mobilization were associated with ES after ASCT. Multivariate analysis showed that age ≥60 years (P = .0014), receiving ASCT at CR (P = .002), and higher number of MNC transfused (P = .026) were associated with ES in total cohort. In plasma cell disease subgroup, age ≥60 years (P = .013), plerixafor-based mobilization (P = .036), and receiving ASCT at CR (P = .002) were associated with ES. Patients with more risk factors had a higher risk of ES. The 1-year probabilities of relapse, non-relapse mortality, and survival were comparable between patients with and without ES. Thus, plerixafor-based mobilization may influence the composition of T lymphocytes in grafts and increase the risk of ES, particularly in patients with plasma cell disease.

Published
2024
Full Text
View/download PDF

2. Similarity Search Method in Time Series Based on Curvature Distance

Author

Bo-ning Liu, Zhan-lei Wang, Jian-ye Zhang, and Peng Zhang

Subjects
Similarity (network science), Series (mathematics), Nearest neighbor search, Normalized compression distance, Mathematical analysis, Jaro–Winkler distance, Electrical and Electronic Engineering, Curvature, Topology, Mathematics
Published
2013

3. Effects of moderate pressure on premeability and viability of Saccharomyces cerevisiae cells

Author

Yujie Dai, Bo-Ning Liu, Jiandong Cui, Changsheng Qiao, Na-Chen, and Shiru Jia

Subjects
biology, Membrane permeability, Chemistry, General Chemical Engineering, Saccharomyces cerevisiae, General Chemistry, biology.organism_classification, Yeast, Cell membrane, medicine.anatomical_structure, Biochemistry, Cell leakage, Permeability (electromagnetism), Pressure increase, medicine, Biophysics, Viability assay
Abstract

With CO2 and N2 as the pressure media, the effects of the moderate pressure (0.1–1.0MPa) and the holding time on the conductivities of the cell suspension of Saccharomyces cerevisiae CICC1447 and Saccharomyces cerevisiae CICC1339, as well as the absorbances of the supernatant (after centrifuged) at 280 nm (A280) and 260 nm (A260) were determined. The membrane permeability of Saccharomyces cerevisiae CICC1447 increased significantly and the cell leakage was aggravated with the pressure increase. For Saccharomyces cerevisiae CICC1339, the conductivity of the cell suspension, A280 and A260 of the supernatant fluctuated with the pressure increase; as a whole, they increased with pressure. Different from high pressure, a moderate pressure not only remarkably improved the permeability of the yeast cell membrane, but also kept yeast cell viability; moreover, the integrity of the yeast cell membrane could be maintained.

Published
2009

4. [Relationship between placental pathology and small-for-gestational age neonates]

Author

Xue-jun, Zhao, Jin-ping, Xu, Bing, Li, Jiu-ling, Qi, Sheng-min, Ping, Hai-yun, Zhu, and Bo-ning, Liu

Subjects
Pregnancy, Placenta, Infant, Small for Gestational Age, Infant, Newborn, Torsion, Mechanical, Birth Weight, Humans, Female, Gestational Age, Hypertension, Pregnancy-Induced, Umbilical Cord
Abstract

To investigate the relationship between pathological abnormalities of placenta and small-for-gestational-age neonates.One hundred placentas of small-for-gestational-age (SGA group) and 200 appropriate-for-gestational-age (AGA group) with single living birth in third trimester were investigated by gross and microscopic examination. The AGA placentas were collected from 2 cases following every SGA placenta. All cases were collected from Shanghai Changning District Maternity and Infant Health Hospital from January 2010 to December 2011.The gestational week, neonatal birth weight, full-term neonatal birth weight, the preterm birth rate and vaginal spontaneous delivery rate were significantly lower in SGA group than that in AGA group (P0.002). Full-term placental volume, placental weight and fetal placental weight ratio were lower in SGA group than that in AGA group (P0.05). Unusual insertion and torsion of umbilical cord were more common in SGA group (P0.05). Syncytial knots increase, avascular villi and villous infarcts were significantly higher in SGA group (P0.005), but there were no significant difference between SGA group and AGA group in intervillous thrombi, chronic villitis and chorangiosis (P0.05). Gestational hypertension disease and abnormality of fetal monitoring were more common in SGA group (P0.05).Gestational hypertension disease is the main clinical cause of SGA. Some placental abnormality can affect the growth and development of intrauterine fetus.

Published
2013

Catalog

Books, media, physical & digital resources
See catalog results