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5. Impact of seasonal blood pressure changes on visit-to-visit blood pressure variability and related cardiovascular outcomes

Author

Mancia, G, Schumacher, H, Böhm, M, Grassi, G, Teo, K, Mahfoud, F, Parati, G, Redon, J, Yusuf, S, Mancia G, Schumacher H, Böhm M, Grassi G, Teo KK, Mahfoud F, Parati G, Redon J, Yusuf S, Mancia, G, Schumacher, H, Böhm, M, Grassi, G, Teo, K, Mahfoud, F, Parati, G, Redon, J, Yusuf, S, Mancia G, Schumacher H, Böhm M, Grassi G, Teo KK, Mahfoud F, Parati G, Redon J, and Yusuf S

Abstract

Background: Visit-to-visit blood pressure (BP) variability associates with an increased risk of cardiovascular events. We investigated the role of seasonal BP modifications on the magnitude of BP variability and its impact on cardiovascular risk. Methods: In 25 390 patients included in the ONTARGET and TRANSCEND trials, the on-treatment systolic (S) BP values obtained by five visits during the first two years of the trials were grouped according to the month in which they were obtained. SBP differences between winter and summer months were calculated for BP variability quintiles (Qs), as quantified by the coefficient of variation (CV) of on-treatment mean SBP from the five visits. The relationship of BP variability with the risk of cardiovascular events and mortality was assessed by the Cox regression model. Results: SBP was approximately 4 mmHg lower in summer than in winter regardless of confounders. Winter/summer SBP differences contributed significantly to each SBP-CV quintile. Increase of SBP-CV from Q1 to Q5 was associated with a progressive increase in the adjusted hazard ratio (HR) of the primary endpoint of the trials, i.e. morbid and fatal cardiovascular events. This association was even stronger after removal of the effect of seasonality from the calculation of SBP-CV. A similar trend was observed for secondary endpoints. Conclusions: Winter/summer SBP differences significantly contribute to visit-to-visit BP variability. However, this contribution does not participate in the adverse prognostic significance of visit-to-visit BP variations, which seems to be more evident after removal of the BP effects of seasonality from visit-to-visit BP variations.

Published
2024

6. Predictors and outcomes in primary depression care (POKAL) – a research training group develops an innovative approach to collaborative care

Author

Gensichen, J, Lukaschek, K, Jung-Sievers, C, Falkai, P, Schmitt, A, Henningsen, P, Dreischulte, T, Pitschel-Walz, G, Krcmar, H, Böhm, M, Prommegger, B, Linde, K, Drescher, A, Schönweger, P, Haas, C, Brand, C, Younesi, P, Vukas, J, Brisnik, V, Schillok, H, Raub, J, Kaupe, L, Biersack, K, Gökce, F, Eder, J, Hattenkofer, L, Reindl-Spanner, Ph, von Schrottenberg, V, Teusen, C, Sterner, Ph, Bühner, M, and Schneider, A

Published
2022
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7. Effects of Single Pill Combinations Compared to Identical Multi Pill Therapy on Outcomes in Hypertension, Dyslipidemia and Secondary Cardiovascular Prevention: The START-Study

Author

Wilke T, Weisser B, Predel HG, Schmieder R, Wassmann S, Gillessen A, Blettenberg J, Maywald U, Randerath O, Mueller S, and Böhm M

Subjects
single pill, adherence, cardiovascular outcomes, mortality, prognosis, clinical practice, Internal medicine, RC31-1245
Abstract

Thomas Wilke,1 Burkhard Weisser,2 Hans-Georg Predel,3 Roland Schmieder,4 Sven Wassmann,5 Anton Gillessen,6 Jörg Blettenberg,7 Ulf Maywald,8 Olaf Randerath,9 Sabrina Mueller,10 Michael Böhm11 1Institut für Pharmakoökonomie und Arzneimittellogistik (IPAM)/Institute for Pharmacoeconomics and Pharmaceutical Logistics, Wismar, Germany; 2Institute of Sports Science, Christian-Albrechts-University of Kiel, Kiel, Germany; 3Institute of Cardiology and Sports Medicine, German Sport University, Cologne, Germany; 4Department of Nephrology and Hypertension, University Hospital Erlangen, Friedrich Alexander University Erlangen Nürnberg, Erlangen, Germany; 5Faculty of Medicine, Cardiology Pasing, Munich and University of the Saarland, Homburg/Saar, Germany; 6Department of Internal Medicine, Herz-Jesu-Hospital, Münster, Germany; 7Practice Dr. J. Blettenberg, Lindlar, Germany; 8AOK PLUS – The Health Insurance for Sachsen und Thüringen; GB Medicines/Remedies, Dresden, Germany; 9Medical Department, APONTIS PHARMA GmbH & Co.KG, Monheim, Germany; 10Ingress-Health HWM GmbH, Wismar, Germany; 11Clinic for Internal Medicine III, University Clinic of Saarland, Saarland University, Homburg/Saar, GermanyCorrespondence: Thomas Wilke, Institute of Pharmacoeconomics and Medication Logistics, University of Wismar, Alter Holzhafen 19, Wismar, 23966, Germany, Tel +4938417581014, Fax +4938417581011, Email Thomas.wilke@ipam-wismar.deAim: Current guidelines for the treatment of arterial hypertension (AH) or cardiovascular (CV) prevention recommend combination drug treatments with single pill combinations (SPC) to improve adherence to treatment. We aimed to assess whether the SPC concept is clinically superior to multi pill combination (MPC) with identical drugs.Methods and Results: In an explorative study, we analyzed anonymized claims data sets of patients treated with CV drugs for hypertension and/or CV disorders who were insured by the German AOK PLUS statutory health fund covering 01/07/2012-30/06/2018. Patients at age ≥ 18 years who received either a SPC or MPC with identical drugs were followed for up to one year. A one to one propensity score matching (PSM) was applied within patient groups who started identical drug combinations, and results were reported as incidence rate ratios (IRRs) as well as hazard ratios (HRs). After PSM, data from 59,336 patients were analyzed. In 30 out of 56 IRR analyses, superiority of SPC over MPC was shown. In 5 out of 7 comparisons, the HR for the composite outcome of all-cause death and all-cause hospitalizations was in favor of the SPC regimen (SPC versus MPC): valsartan/amlodipine: HR=0.87 (95% CI: 0.84– 0.91, p ≤ 0.001); candesartan/amlodipine: 0.77 (95% CI: 0.65– 0.90, p = 0.001); valsartan/amlodipine/hydrochlorothiazide: HR=0.68 (95% CI: 0.61– 0.74, p ≤ 0.001); ramipril/amlodipine: HR=0.80 (95% CI: 0.77– 0.83, p ≤ 0.001); acetylsalicylic acid (ASA)/atorvastatin/ramipril: HR=0.64 (95% CI: 0.47– 0.88, p = 0.005).Conclusion: SPC regimens are associated with a lower incidence of CV events and lower all-cause mortality in clinical practice. SPC regimens should generally be preferred to improve patient’s prognosis.Keywords: single pill, adherence, cardiovascular outcomes, mortality, prognosis, clinical practice

Published
2022

8. Aktualizace Doporučení ESC pro diagnostiku a léčbu akutního a chronického srdečního selhání 2021. Vypracovaná Pracovní skupinou pro diagnostiku a léčbu akutního a chronického srdečního selhání Evropské kardiologické společnosti (ESC). Se zvláštním přispěním Evropské asociace srdečního selhání ESC.

Author

TA, McDonagh, primary, Metra, M, additional, Adamo, M, additional, RS, Gardner, additional, Baumbach, A, additional, Böhm, M, additional, Burri, H, additional, Butler, J, additional, Čelutkienė, J, additional, Chioncel, O, additional, JGF, Cleland, additional, MG, Crespo-Leiro, additional, Farmakis, D, additional, Gilard, M, additional, Heymans, S, additional, AW, Hoes, additional, Jaarsma, T, additional, EA, Jankowska, additional, Lainscak, M, additional, CSP, Lam, additional, AR, Lyon, additional, JJV, McMurray, additional, Mebazaa, A, additional, Mindham, R, additional, Muneretto, C, additional, MF, Piepoli, additional, Price, S, additional, GMC, Rosano, additional, Ruschitzka, F, additional, AK, Skibelund, additional, TA, McDonagh, additional, Krejčí, Jan, additional, Špinarová, Lenka, additional, Pařenica, Jiří, additional, Chaloupka, Anna, additional, and Veselý, Jiří, additional

Published
2024
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10. Impact of Pseudoexfoliative Syndrome on Effective Lens Position, Anterior Chamber Depth Changes, and Visual Outcome After Cataract Surgery

Author

Müller M, Pawlowicz K, Böhm M, Hemkeppler E, Lwowski C, Hinzelmann L, Shajari M, and Kohnen T

Subjects
pseudoexfoliative syndrome, effective lens position, anterior depth changes, cataract surgery, Ophthalmology, RE1-994
Abstract

Michael Müller, Katarzyna Pawlowicz, Myriam Böhm, Eva Hemkeppler, Christoph Lwowski, Lisa Hinzelmann, Mehdi Shajari, Thomas Kohnen Department of Ophthalmology, Goethe-University, Frankfurt, GermanyCorrespondence: Thomas KohnenDepartment of Ophthalmology, Goethe-University, Theodor-Stern-Kai 7, Frankfurt, 60590, GermanyTel +49 69 6301 3945Fax +49 69 6301 3893Email thomas.kohnen@kgu.dePurpose: To compare the effective lens position (ELP), anterior chamber depth (ACD) changes, and visual outcomes in patients with and without pseudoexfoliation syndrome (PEX) after cataract surgery.Design: Prospective, randomized, fellow-eye controlled clinical case series.Methods: This prospective comparative case series enrolled 56 eyes of 56 consecutive patients with (n = 28) or without PEX (n = 28) and clinically significant cataract who underwent standard phacoemulsification and were implanted with single-piece acrylic posterior chamber intraocular lenses (IOLs). The primary outcome parameters were the ACD referring to the distance between the corneal anterior surface and the lens anterior surface, which is an indicator of the postoperative axial position of the IOL (the so-called ELP) and distance corrected visual acuity (DCVA).Results: Before surgery, the ACD was 2.54 ± 0.42 mm in the PEX group and 2.53 ± 0.38 mm in the control group (p = 0.941). Postoperatively, the ACD was 4.29 ± 0.71 mm in the PEX group and 4.33 ± 0.72 mm in the normal group, respectively (p = 0.533). There was no significant difference in ACD changes between groups (PEX group: 1.75 ± 0.74 mm, control group: 1.81 ± 0.61 mm, p = 0.806) and DCVA pre- (p = 0.469) and postoperatively (PEX group: 0.11 ± 0.13 logMAR, control group: 0.09 ± 0.17 logMAR, p = 0.245) between groups.Conclusion: Preoperative and postoperative ACD, as an indicator of ELP, between PEX eyes and healthy eyes after cataract surgery showed no significant difference. Phacoemulsification induced similar changes in eyes with PEX compared to healthy eyes.Keywords: pseudoexfoliative syndrome, effective lens position, anterior chamber depth changes, cataract surgery

Published
2021

13. Accelerating and standardising IUCN Red List assessments with sRedList

Author

Cazalis, V., Di Marco, M., Zizka, A., Butchart, S.H.M., González-Suárez, M., Böhm, M., Bachman, S.P., Hoffmann, M., Rosati, I., De Leo, F., Jung, M., Benítez-López, A., Clausnitzer, V., Cardoso, P., Brooks, T.M., Mancini, G., Lucas, P.M., Young, B.E., Akçakaya, H.R., Schipper, A.M., Hilton-Taylor, C., Pacifici, M., Meyer, C., Santini, L., Cazalis, V., Di Marco, M., Zizka, A., Butchart, S.H.M., González-Suárez, M., Böhm, M., Bachman, S.P., Hoffmann, M., Rosati, I., De Leo, F., Jung, M., Benítez-López, A., Clausnitzer, V., Cardoso, P., Brooks, T.M., Mancini, G., Lucas, P.M., Young, B.E., Akçakaya, H.R., Schipper, A.M., Hilton-Taylor, C., Pacifici, M., Meyer, C., and Santini, L.

Abstract

The IUCN Red List of Threatened Species underpins much decision-making in conservation and plays a key role in monitoring the status and trends of biodiversity. However, the shortage of funds and assessor capacity slows the uptake of novel data and techniques, hampering its currency, applicability, consistency and long-term viability. To help address this, we developed sRedList, a user-friendly online platform that assists Red List assessors through a step-by-step process to estimate key parameters in a standardised and reproducible fashion. Through the platform, assessors can swiftly generate outputs including species' range maps, lists of countries of occurrence, lower and upper bounds of area of occupancy, habitat preferences, trends in area of habitat, and levels of fragmentation. sRedList is compliant with the IUCN Red List guidelines and outputs are interoperable with the Species Information Service (SIS; the IUCN Red List database) in support of global, regional and national assessments and reassessments. sRedList can also help assessors prioritise species for reassessment. sRedList was released in October 2023, with a complete documentation package (including text documentation, ‘cheatsheets’, and 15 video tutorials), and will soon be highlighted in the official Red List online training course. sRedList will help to bridge the gap between extinction risk research and Red List assessment practice, increase the taxonomic coverage and consistency of assessments, and ensure the IUCN Red List is up-to-date to best support conservation policy and practice across the world.

Published
2024
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14. The PANDA Barrel DIRC

Author

Dzhygadlo, R., Belias, A., Gerhardt, A., Lehmann, D., Peters, K., Schepers, G., Schwarz, C., Schwiening, J., Traxler, M., Wolf, Y., Schmitt, L., Böhm, M., Gumbert, K., Krauss, S., Lehmann, A., Miehling, D., Düren, M., Hayrapetyan, A., Köseoglu, I., Schmidt, M., Wasem, T., Sfienti, C., Ali, A., Dzhygadlo, R., Belias, A., Gerhardt, A., Lehmann, D., Peters, K., Schepers, G., Schwarz, C., Schwiening, J., Traxler, M., Wolf, Y., Schmitt, L., Böhm, M., Gumbert, K., Krauss, S., Lehmann, A., Miehling, D., Düren, M., Hayrapetyan, A., Köseoglu, I., Schmidt, M., Wasem, T., Sfienti, C., and Ali, A.

Abstract

The PANDA experiment at the international accelerator Facility for Antiproton and Ion Research in Europe (FAIR), Darmstadt, Germany, will address fundamental questions of hadron physics using $\bar{p}p$ annihilations. Excellent Particle Identification (PID) over a large range of solid angles and particle momenta will be essential to meet the objectives of the rich physics program. Charged PID in the target region will be provided by a Barrel DIRC (Detection of Internally Reflected Cherenkov light) counter. The Barrel DIRC, covering the polar angle range of 22-140 degrees, will provide a $\pi/K$ separation power of at least 3 standard deviations for charged particle momenta up to 3.5 GeV/c. The design of the Barrel DIRC features narrow radiator bars made from synthetic fused silica, an innovative multi-layer spherical lens focusing system, a prism-shaped synthetic fused silica expansion volume, and an array of lifetime-enhanced Microchannel Plate PMTs (MCP-PMTs) to detect the hit location and arrival time of the Cherenkov photons. Detailed Monte-Carlo simulations were performed, and reconstruction methods were developed to study the performance of the system. All critical aspects of the design and the performance were validated with system prototypes in a mixed hadron beam at the CERN PS. In 2020 the PANDA Barrel DIRC project advanced from the design stage to component fabrication. The series production of the fused silica bars was successfully completed in 2021 and delivery of the MCP-PMTs started in May 2022., Comment: XI International Workshop on Ring Imaging Cherenkov Detectors

Published
2024
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15. Diversity gradients of terrestrial vertebrates – substantial variations about a common theme

Author

Raz, T., Allison, A., Avila, L. J., Bauer, A. M., Böhm, M., Caetano, G. H. de O., Colli, G., Doan, T. M., Doughty, P., Grismer, L., Itescu, Y., Kraus, F., Martins, M., Morando, M., Murali, G., Nagy, Z. T., Nogueira, C. de C., Novosolov, M., Oliver, P. M., Passos, P., Pincheira-Donoso, D., Sindaco, R., Slavenko, A., Torres-Carvajal, O., Uetz, P., Wagner, P., Zimin, A., Roll, U., Meiri, S., Raz, T., Allison, A., Avila, L. J., Bauer, A. M., Böhm, M., Caetano, G. H. de O., Colli, G., Doan, T. M., Doughty, P., Grismer, L., Itescu, Y., Kraus, F., Martins, M., Morando, M., Murali, G., Nagy, Z. T., Nogueira, C. de C., Novosolov, M., Oliver, P. M., Passos, P., Pincheira-Donoso, D., Sindaco, R., Slavenko, A., Torres-Carvajal, O., Uetz, P., Wagner, P., Zimin, A., Roll, U., and Meiri, S.

Abstract

Environmental factors, such as temperature, precipitation, and elevation, explain most of the variation in species richness at the global scale. Nevertheless, richness patterns may have different drivers across taxa and regions. To date, a comprehensive global examination of how various factors such as climate or topography drive patterns of species richness across all terrestrial vertebrates, using the same methods and predictors, has been lacking. Recent advances in species-distribution data allowed us to model and examine the richness pattern of all terrestrial tetrapods comprehensively. We tested the relationship between environmental and biogeographical variables and richness of amphibians (5983 species), birds (9630), mammals (5004), reptiles (8939), and tetrapods as a whole, globally, and across biogeographical realms. We studied the effects of climatic, ecological, and biogeographic drivers using generalized additive models. Richness patterns and their environmental associations varied among taxa and realms. Overall precipitation was the predominant richness predictor. However, temperature was more important in realms where both cold and warm conditions exist. In the Indomalayan realm, elevational range was very important. Richness patterns of mammals, birds, and amphibians were strongly related to precipitation whereas reptile richness was mostly associated with temperature. Our results support the universal importance of precipitation but also suggest that future global-scaled research should incorporate other relevant variables other than climate, such as elevational range, to gain a better understanding of the richness–environment relationship. By doing so, we can further advance our knowledge of the complex relationships between biodiversity and the environment.

Published
2024

17. An overview of benefits and risks of chronic melanocortin‐1 receptor activation.

Author

Böhm, M., Robert, C., Malhotra, S., Clément, K., and Farooqi, S.

Subjects
*CYCLIC adenylic acid, *HUMAN skin color, *SEXUAL desire disorders, *CELL receptors, *ADENYLATE cyclase, *MELANINS
Abstract

The melanocortin‐1 receptor (MC1R) is a G protein‐coupled receptor that plays a pivotal role in human skin pigmentation, melanin synthesis, redox homeostasis and inflammation. Loss‐of‐function MC1R variants suppress G protein‐coupled receptor coupling or cell surface expression leading to a decrease in adenyl cyclase activation and intracellular levels of cyclic adenosine monophosphate. Chronic activation of MC1R can occur in certain medical conditions such as Addison's disease and physiologic states such as pregnancy melasma. MC1R activation is more commonly caused by environmental exposure to ultraviolet (UV) radiation. Approved pharmacologic melanocortin agonists that activate MC1R signalling in a targeted manner or as a bystander effect have recently become available for erythropoietic protoporphyria, sexual desire disorders, monogenic obesity and syndromic obesity. Further, small peptide analogues of α–melanocortin‐stimulating hormone, human MC1R selective agonists, are photoprotective, decreasing the adverse impact of UV radiation (a primary risk factor for skin cancer) and are being investigated as potential chemoprevention strategies. MC1R activation through induction of UV‐protective skin pigmentation increased DNA repair, and control of aberrant cell growth may reduce the risk of melanoma but importantly does not prevent melanoma particularly in individuals with risk factors and regular skin examination remains critical in high‐risk individuals. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Diversity gradients of terrestrial vertebrates – substantial variations about a common theme

Author

Raz, T., primary, Allison, A., additional, Avila, L. J., additional, Bauer, A. M., additional, Böhm, M., additional, Caetano, G. H. de O., additional, Colli, G., additional, Doan, T. M., additional, Doughty, P., additional, Grismer, L., additional, Itescu, Y., additional, Kraus, F., additional, Martins, M., additional, Morando, M., additional, Murali, G., additional, Nagy, Z. T., additional, Nogueira, C. de C., additional, Novosolov, M., additional, Oliver, P. M., additional, Passos, P., additional, Pincheira‐Donoso, D., additional, Sindaco, R., additional, Slavenko, A., additional, Torres‐Carvajal, O., additional, Uetz, P., additional, Wagner, P., additional, Zimin, A., additional, Roll, U., additional, and Meiri, S., additional

Published
2023
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24. Outcomes Following Radiofrequency Renal Denervation According to Antihypertensive Medications: Subgroup Analysis of the Global SYMPLICITY Registry DEFINE

Author

Mahfoud, F, Mancia, G, Schmieder, R, Ruilope, L, Narkiewicz, K, Schlaich, M, Williams, B, Ribichini, F, Weil, J, Almerri, K, Sharif, F, Lauder, L, Wanten, M, Fahy, M, Böhm, M, Mahfoud F., Mancia G., Schmieder R. E., Ruilope L., Narkiewicz K., Schlaich M., Williams B., Ribichini F., Weil J., Almerri K., Sharif F., Lauder L., Wanten M., Fahy M., Böhm M., Mahfoud, F, Mancia, G, Schmieder, R, Ruilope, L, Narkiewicz, K, Schlaich, M, Williams, B, Ribichini, F, Weil, J, Almerri, K, Sharif, F, Lauder, L, Wanten, M, Fahy, M, Böhm, M, Mahfoud F., Mancia G., Schmieder R. E., Ruilope L., Narkiewicz K., Schlaich M., Williams B., Ribichini F., Weil J., Almerri K., Sharif F., Lauder L., Wanten M., Fahy M., and Böhm M.

Abstract

Background: The Global SYMPLICITY Registry DEFINE (Denervation Findings in Real World) investigates radiofrequency renal denervation (RDN) in a broad range of patients with hypertension. We evaluated whether the number or type of antihypertensive medications were associated with increased long-term blood pressure (BP) reductions and cardiovascular outcomes following radiofrequency RDN. Methods: Patients underwent radiofrequency RDN and were categorized by baseline number (0-3 and ≥4) and different combinations of medication classes. BP changes were compared between groups through 36 months. Individual and composite major adverse cardiovascular events were analyzed. Results: Of 2746 evaluable patients, 18% were prescribed 0 to 3 and 82% prescribed ≥4 classes. At 36 months, office systolic BP significantly decreased (P<0.0001) by -19.0±28.3 and -16.2±28.6 mm Hg in the 0 to 3 and ≥4 class groups, respectively. Twenty-four-hour mean systolic BP significantly decreased (P<0.0001) by -10.7±19.7 and -8.9±20.5 mm Hg, respectively. BP reduction was similar between the medication subgroups. Antihypertensive medication classes decreased from 4.6±1.4 to 4.3±1.5 (P<0.0001). Most decreased (31%) or had no changes (47%) to the number of medications, while 22% increased. The number of baseline antihypertensive medication classes was inversely related to the change in prescribed classes at 36 months (P<0.001). Cardiovascular event rates were generally low. More patients in the ≥4 compared with 0 to 3 medication classes had myocardial infarction at 36 months (2.8% versus 0.3%; P=0.009). Conclusions: Radiofrequency RDN reduced BP safely through 36 months, independent of the number and type of baseline antihypertensive medication classes. More patients decreased than increased their number of medications. Radiofrequency RDN is a safe and effective adjunctive therapy regardless of antihypertensive medication regimen. Registration: URL: https://www. Clinicaltrials: gov; Uniqu

Published
2023

28. Myokarditis

Author

Kindermann, I., primary, Klingel, K., additional, and Böhm, M., additional

Published
2021
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29. PANDA Phase One: PANDA collaboration

Author

Barucca, G., Davì, F., Lancioni, G., Mengucci, P., Montalto, L., Natali, P. P., Paone, N., Rinaldi, D., Scalise, L., Krusche, B., Steinacher, M., Liu, Z., Liu, C., Liu, B., Shen, X., Sun, S., Zhao, G., Zhao, J., Albrecht, M., Alkakhi, W., Bökelmann, S., Coen, S., Feldbauer, F., Fink, M., Frech, J., Freudenreich, V., Fritsch, M., Grochowski, J., Hagdorn, R., Heinsius, F. H., Held, T., Holtmann, T., Keshk, I., Koch, H., Kopf, B., Kümmel, M., Küßner, M., Li, J., Linzen, L., Maldaner, S., Oppotsch, J., Pankonin, S., Pelizäus, M., Pflüger, S., Reher, J., Reicherz, G., Schnier, C., Steinke, M., Triffterer, T., Wenzel, C., Wiedner, U., Denizli, H., Er, N., Keskin, U., Yerlikaya, S., Yilmaz, A., Beck, R., Chauhan, V., Hammann, C., Hartmann, J., Ketzer, B., Müllers, J., Salisbury, B., Schmidt, C., Thoma, U., Urban, M., Bianconi, A., Bragadireanu, M., Pantea, D., Rimjaem, S., Domagala, M., Filo, G., Lisowski, E., Lisowski, F., Michałek, M., Poznański, P., Płazek, J., Korcyl, K., Lebiedowicz, P., Pysz, K., Schäfer, W., Szczurek, A., Firlej, M., Fiutowski, T., Idzik, M., Moron, J., Swientek, K., Terlecki, P., Korcyl, G., Lalik, R., Malige, A., Moskal, P., Nowakowski, K., Przygoda, W., Rathod, N., Salabura, P., Smyrski, J., Augustin, I., Böhm, R., Lehmann, I., Schmitt, L., Varentsov, V., Al-Turany, M., Belias, A., Deppe, H., Dzhygadlo, R., Flemming, H., Gerhardt, A., Götzen, K., Heinz, A., Jiang, P., Karabowicz, R., Koch, S., Kurilla, U., Lehmann, D., Lühning, J., Lynen, U., Orth, H., Peters, K., Pütz, J., Ritman, J., Schepers, G., Schmidt, C. J., Schwarz, C., Schwiening, J., Täschner, A., Traxler, M., Voss, B., Wieczorek, P., Abazov, V., Alexeev, G., Barabanov, M. Yu., Dodokhov, V. Kh., Efremov, A., Fechtchenko, A., Galoyan, A., Golovanov, G., Koshurnikov, E. K., Lobanov, Y. Yu., Olshevskiy, A. G., Piskun, A. A., Samartsev, A., Shimanski, S., Skachkov, N. B., Skachkova, A. N., Strokovsky, E. A., Tokmenin, V., Uzhinsky, V., Verkheev, A., Vodopianov, A., Zhuravlev, N. I., Watts, D., Böhm, M., Eyrich, W., Lehmann, A., Miehling, D., Pfaffinger, M., Seth, K., Xiao, T., Ali, A., Hamdi, A., Himmelreich, M., Krebs, M., Nakhoul, S., Nerling, F., Gianotti, P., Lucherini, V., Bracco, G., Bodenschatz, S., Brinkmann, K. T., Brück, L., Diehl, S., Dormenev, V., Düren, M., Erlen, T., Hahn, C., Hayrapetyan, A., Hofmann, J., Kegel, S., Khalid, F., Köseoglu, I., Kripko, A., Kühn, W., Metag, V., Moritz, M., Nanova, M., Novotny, R., Orsich, P., Pereira-de-Lira, J., Sachs, M., Schmidt, M., Schubert, R., Strickert, M., Wasem, T., Zaunick, H. G., Tomasi-Gustafsson, E., Glazier, D., Ireland, D., Seitz, B., Kappert, R., Kavatsyuk, M., Loehner, H., Messchendorp, J., Rodin, V., Kalita, K., Huang, G., Liu, D., Peng, H., Qi, H., Sun, Y., Zhou, X., Kunze, M., Azizi, K., Olgun, A. T., Tavukoglu, Z., Derichs, A., Dosdall, R., Esmail, W., Gillitzer, A., Goldenbaum, F., Grunwald, D., Jokhovets, L., Kannika, J., Kulessa, P., Orfanitski, S., Perez-Andrade, G., Prasuhn, D., Prencipe, E., Rosenthal, E., Schadmand, S., Schmitz, R., Scholl, A., Sefzick, T., Serdyuk, V., Stockmanns, T., Veretennikov, D., Wintz, P., Wüstner, P., Xu, H., Zhou, Y., Cao, X., Hu, Q., Liang, Y., Rigato, V., Isaksson, L., Achenbach, P., Corell, O., Denig, A., Distler, M., Hoek, M., Lauth, W., Leithoff, H. H., Merkel, H., Müller, U., Petersen, J., Pochodzalla, J., Schlimme, S., Sfienti, C., Thiel, M., Bleser, S., Bölting, M., Capozza, L., Dbeyssi, A., Ehret, A., Klasen, R., Kliemt, R., Maas, F., Motzko, C., Noll, O., Piñeiro, D. Rodríguez, Schupp, F., Steinen, M., Wolff, S., Zimmermann, I., Kazlou, D., Korzhik, M., Missevitch, O., Balanutsa, P., Chernetsky, V., Demekhin, A., Dolgolenko, A., Fedorets, P., Gerasimov, A., Golubev, A., Kantsyrev, A., Kirin, D. Y., Kristi, N., Ladygina, E., Luschevskaya, E., Matveev, V. A., Panjushkin, V., Stavinskiy, A. V., Balashoff, A., Boukharov, A., Bukharova, M., Malyshev, O., Vishnevsky, E., Bonaventura, D., Brand, P., Hetz, B., Hüsken, N., Kellers, J., Khoukaz, A., Klostermann, D., Mannweiler, C., Vestrick, S., Bumrungkoh, D., Herold, C., Khosonthongkee, K., Kobdaj, C., Limphirat, A., Manasatitpong, K., Nasawad, T., Pongampai, S., Simantathammakul, T., Srisawad, P., Wongprachanukul, N., Yan, Y., Yu, C., Zhang, X., Zhu, W., Antokhin, E., Barnyakov, A. Yu., Beloborodov, K., Blinov, V. E., Kuyanov, I. A., Pivovarov, S., Pyata, E., Tikhonov, Y., Blinov, A. E., Kononov, S., Kravchenko, E. A., Lattery, M., Boca, G., Duda, D., Finger, M., Finger, Jr., M., Kveton, A., Prochazka, I., Slunecka, M., Volf, M., Jary, V., Korchak, O., Marcisovsky, M., Neue, G., Novy, J., Tomasek, L., Tomasek, M., Virius, M., Vrba, V., Abramov, V., Bukreeva, S., Chernichenko, S., Derevschikov, A., Ferapontov, V., Goncharenko, Y., Levin, A., Maslova, E., Melnik, Y., Meschanin, A., Minaev, N., Mochalov, V., Moiseev, V., Morozov, D., Nogach, L., Poslavskiy, S., Ryazantsev, A., Ryzhikov, S., Semenov, P., Shein, I., Uzunian, A., Vasiliev, A., Yakutin, A., Belostotski, S., Fedotov, G., Izotov, A., Manaenkov, S., Miklukho, O., Cederwall, B., Preston, M., Tegner, P. E., Wölbing, D., Gandhi, K., Rai, A. K., Godre, S., Crede, V., Dobbs, S., Eugenio, P., Bussa, M. P., Spataro, S., Calvo, D., De Remigis, P., Filippi, A., Mazza, G., Wheadon, R., Iazzi, F., Lavagno, A., Akram, A., Calen, H., Andersson, W. Ikegami, Johansson, T., Kupsc, A., Marciniewski, P., Papenbrock, M., Regina, J., Rieger, J., Schönning, K., Wolke, M., Chlopik, A., Kesik, G., Melnychuk, D., Tarasiuk, J., Wojciechowski, M., Wronka, S., Zwieglinski, B., Amsler, C., Bühler, P., Marton, J., Zimmermann, S., Fischer, C. S., Haidenbauer, J., Hanhart, C., Lutz, M. F. M., and Ryan, Sinéad M.

Published
2021
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32. The PANDA Barrel DIRC

Author

Dzhygadlo, R., primary, Belias, A., additional, Gerhardt, A., additional, Lehmann, D., additional, Peters, K., additional, Schepers, G., additional, Schwarz, C., additional, Schwiening, J., additional, Traxler, M., additional, Wolf, Y., additional, Schmitt, L., additional, Böhm, M., additional, Gumbert, K., additional, Krauss, S., additional, Lehmann, A., additional, Miehling, D., additional, Düren, M., additional, Hayrapetyan, A., additional, Köseoglu, I., additional, Schmidt, M., additional, Wasem, T., additional, Sfienti, C., additional, and Ali, A., additional

Published
2023
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34. Performance of the most recent Microchannel-Plate PMTs for the PANDA DIRC detectors at FAIR

Author

Krauss, S., primary, Böhm, M., additional, Gumbert, K., additional, Lehmann, A., additional, Miehling, D., additional, Belias, A., additional, Dzhygadlo, R., additional, Gerhardt, A., additional, Lehmann, D., additional, Peters, K., additional, Schepers, G., additional, Schwarz, C., additional, Schwiening, J., additional, Traxler, M., additional, Wolf, Y., additional, Schmitt, L., additional, Düren, M., additional, Hayrapetyan, A., additional, Köseglu, I., additional, Schmidt, M., additional, Wasem, T., additional, Sfienti, C., additional, and Ali, A., additional

Published
2023
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36. Association of medication adherence and depression with the control of low-density lipoprotein cholesterol and blood pressure in patients at high cardiovascular risk

Author

Katzmann JL, Mahfoud F, Böhm M, Schulz M, and Laufs U

Subjects
LDL cholesterol, blood pressure, statin, adherence, MMAS-8, depression, Medicine (General), R5-920
Abstract

Julius L Katzmann,1 Felix Mahfoud,2 Michael Böhm,2 Martin Schulz,3,4 Ulrich Laufs1 1Department of Cardiology, Universitätsklinikum Leipzig, Leipzig, Germany; 2Medical Clinic III, Cardiology, Angiology, Intensive Care, Universitätsklinikum des Saarlandes, Homburg, Germany; 3Department of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universität Berlin, Berlin, Germany; 4Department of Medicine, ABDA – Federal Union of German Associations of Pharmacists, Berlin, Germany Background: Many patients at high cardiovascular risk do not reach targets for low-density lipoprotein cholesterol (LDL-C) and blood pressure (BP). Depression is a frequent comorbidity in these patients and contributes to poor medication adherence.Objective: The aim of this study was to elucidate the associations between adherence to lipid- and BP-lowering drugs, the diagnosis of depression, and the control of LDL-C and BP.Patients and methods: This study was conducted as multicenter, single-visit cross-sectional study in Germany. Adherence was assessed by the Morisky Medication Adherence Scale-8 (MMAS-8), and depression was assessed as documented in the patient chart.Results: A total of 3,188 ambulatory patients with hypercholesterolemia (39.8%), stable coronary artery disease (CAD; 7.4%), or both (52.9%) were included. Patients had a history of myocardial infarction (30.8%), diabetes (42.0%), were smokers (19.7%), and 16.1% had the investigator-reported diagnosis of depression. High or moderate adherence to lipid-lowering medication compared to low adherence was associated with lower LDL-C levels (105.5±38.3 vs 120.8±42.4 mg/dL) and lower BP (systolic BP 133.4±14.5 vs 137.9±13.9 mmHg, diastolic BP 78.3±9.6 vs 81.8±9.6 mmHg) and with a higher proportion of patients achieving the guideline-recommended LDL-C (16.9% vs 10.1%) and BP target (52.2% vs 40.8%, all comparisons P

Published
2018

38. The potential of ΛΞ- and ΛΞ- studies with PANDA at FAIR

Author

Barucca, G., Davì, F., Lancioni, G., Mengucci, P., Montalto, L., Natali, P. P., Paone, N., Rinaldi, D., Scalise, L., Erni, W., Krusche, B., Steinacher, M., Walford, N., Cao, N., Liu, Z., Liu, C., Liu, B., Shen, X., Sun, S., Tao, J., Xiong, X. A., Zhao, G., Zhao, J., Albrecht, M., Alkakhi, W., Bökelmann, S., Feldbauer, F., Fink, M., Frech, J., Freudenreich, V., Fritsch, M., Hagdorn, R., Heinsius, F. H., Held, T., Holtmann, T., Keshk, I., Koch, H., Kopf, B., Kuhlmann, M., Kümmel, M., Küßner, M., Li, J., Mustafa, A., Pelizäus, M., Pitka, A., Reher, J., Reicherz, G., Richter, M., Schnier, C., Sohl, L., Steinke, M., Triffterer, T., Wenzel, C., Wiedner, U., Denizli, H., Er, N., Beck, R., Hammann, C., Hartmann, J., Ketzer, B., Müllers, J., Rossbach, M., Salisbury, B., Schmidt, C., Thoma, U., Urban, M., Bianconi, A., Bragadireanu, M., Pantea, D., Domagala, M., Filo, G., Lisowski, E., Lisowski, F., Michałek, M., Poznański, P., Płażek, J., Korcyl, K., Kozela, A., Lebiedowicz, P., Pysz, K., Schäfer, W., Szczurek, A., Fiutowski, T., Idzik, M., Swientek, K., Terlecki, P., Korcyl, G., Lalik, R., Malige, A., Moskal, P., Nowakowski, K., Przygoda, W., Rathod, N., Rudy, Z., Salabura, P., Smyrski, J., Augustin, I., Böhm, R., Lehmann, I., Schmitt, L., Varentsov, V., Al-Turany, M., Belias, A., Deppe, H., Dzhygadlo, R., Flemming, H., Gerhardt, A., Götzen, K., Heinz, A., Jiang, P., Karabowicz, R., Koch, S., Kurilla, U., Lehmann, D., Lühning, J., Lynen, U., Orth, H., Peters, K., Rieger, J., Saito, T., Schepers, G., Schmidt, C. J., Schwarz, C., Schwiening, J., Täschner, A., Traxler, M., Voss, B., Wieczorek, P., Abazov, V., Alexeev, G., Arefiev, V. A., Astakhov, V., Barabanov, M. Yu., Batyunya, B. V., Dodokhov, V. Kh., Efremov, A., Fechtchenko, A., Galoyan, A., Golovanov, G., Koshurnikov, E. K., Lobanov, Y. Yu., Olshevskiy, A. G., Piskun, A. A., Samartsev, A., Shimanski, S., Skachkov, N. B., Skachkova, A. N., Strokovsky, E. A., Tokmenin, V., Uzhinsky, V., Verkheev, A., Vodopianov, A., Zhuravlev, N. I., Branford, D., Watts, D., Böhm, M., Eyrich, W., Lehmann, A., Miehling, D., Pfaffinger, M., Quin, N., Robison, L., Seth, K., Xiao, T., Bettoni, D., Ali, A., Hamdi, A., Himmelreich, M., Krebs, M., Nakhoul, S., Nerling, F., Belousov, A., Kisel, I., Kozlov, G., Pugach, M., Zyzak, M., Bianchi, N., Gianotti, P., Lucherini, V., Bracco, G., Bettner, Y., Bodenschatz, S., Brinkmann, K. T., Brück, L., Diehl, S., Dormenev, V., Düren, M., Erlen, T., Föhl, K., Hahn, C., Hayrapetyan, A., Hofmann, J., Kegel, S., Kesselkaul, M., Köseoglu, I., Kripko, A., Kühn, W., Lange, J. S., Metag, V., Moritz, M., Nanova, M., Novotny, R., Orsich, P., Pereira-de-Lira, J., Peter, M., Sachs, M., Schmidt, M., Schubert, R., Stenzel, H., Straube, M., Strickert, M., Thöring, U., Wasem, T., Wohlfahrt, B., Zaunick, H. G., Tomasi-Gustafsson, E., Glazier, D., Ireland, D., Seitz, B., Deepak, P. N., Kulkarni, A., Kappert, R., Kavatsyuk, M., Loehner, H., Messchendorp, J., Rodin, V., Schakel, P., Vejdani, S., Dutta, K., Kalita, K., Huang, G., Liu, D., Peng, H., Qi, H., Sun, Y., Zhou, X., Kunze, M., Azizi, K., Derichs, A., Dosdall, R., Esmail, W., Gillitzer, A., Goldenbaum, F., Grunwald, D., Jokhovets, L., Kannika, J., Kulessa, P., Orfanitski, S., Pérez Andrade, G., Prasuhn, D., Prencipe, E., Pütz, J., Ritman, J., Rosenthal, E., Schadmand, S., Schmitz, R., Scholl, A., Sefzick, T., Serdyuk, V., Stockmanns, T., Veretennikov, D., Wintz, P., Wüstner, P., Xu, H., Zhou, Y., Cao, X., Hu, Q., Li, Z., Li, H., Liang, Y., Ma, X., Rigato, V., Isaksson, L., Achenbach, P., Aycock, A., Corell, O., Denig, A., Distler, M., Hoek, M., Lauth, W., Leithoff, H. H., Liu, Z., Merkel, H., Müller, U., Pochodzalla, J., Schlimme, S., Sfienti, C., Thiel, M., Zambrana, M., Ahmed , S., Bleser, S., Bölting, M., Capozza, L., Dbeyssi, A., Ehret, A., Grasemann, P., Klasen, R., Kliemt, R., Maas, F., Maldaner, S., Morales Morales, C., Motzko, C., Noll, O., Pflüger, S., Rodríguez Piñeiro, D., Schupp, F., Steinen, M., Wolff, S., Zimmermann, I., Fedorov, A., Kazlou, D., Korzhik, M., Missevitch, O., Balashoff, A., Boukharov, A., Malyshev, O., Balanutsa, P., Chernetsky, V., Demekhin, A., Dolgolenko, A., Fedorets, P., Gerasimov, A., Golubev, A., Goryachev, V., Kantsyrev, A., Kirin, D. Y., Kristi, N., Ladygina, E., Luschevskaya, E., Matveev, V. A., Panjushkin, V., Stavinskiy, A. V., Basant, K. N., Kumawat, H., Roy, B., Saxena, A., Yogesh, S., Bonaventura, D., Brand, P., Fritzsch, C., Grieser, S., Hargens, C., Hergemöller, A. K., Hetz, B., Hüsken, N., Kellers, J., Khoukaz, A., Bumrungkoh, D., Herold, C., Khosonthongkee, K., Kobdaj, C., Limphirat, A., Manasatitpong, K., Nasawad, T., Pongampai, S., Simantathammakul, T., Srisawad, P., Wongprachanukul, N., Yan, Y., Yu, C., Zhang, X., Zhu, W., Blinov, A. E., Kononov, S., Kravchenko, E. A., Antokhin, E., Barnyakov, A. Yu., Beloborodov, K., Blinov, V. E., Kuyanov, I. A., Pivovarov, S., Pyata, E., Tikhonov, Y., Kunne, R., Ramstein, B., Hunter, G., Lattery, M., Pace, H., Boca, G., Duda, D., Finger, M., Finger, Jr., M., Kveton, A., Pesek, M., Peskova, M., Prochazka, I., Slunecka, M., Volf, M., Gallus, P., Jary, V., Korchak, O., Marcisovsky, M., Neue, G., Novy, J., Tomasek, L., Tomasek, M., Virius, M., Vrba, V., Abramov, V., Bukreeva, S., Chernichenko, S., Derevschikov, A., Ferapontov, V., Goncharenko, Y., Levin, A., Maslova, E., Melnik, Y., Meschanin, A., Minaev, N., Mochalov, V., Moiseev, V., Morozov, D., Nogach, L., Poslavskiy, S., Ryazantsev, A., Ryzhikov, S., Semenov, P., Shein, I., Uzunian, A., Vasiliev, A., Yakutin, A., Roy, U., Yabsley, B., Belostotski, S., Fedotov, G., Gavrilov, G., Izotov, A., Manaenkov, S., Miklukho, O., Zhdanov, A., Atac, A., Bäck, T., Cederwall, B., Makonyi, K., Preston, M., Tegner, P. E., Wölbing, D., Gandhi, K., Rai, A. K., Godre, S., Crede, V., Dobbs, S., Eugenio, P., Lersch, D., Calvo, D., De Remigis, P., Filippi, A., Mazza, G., Rivetti, A., Wheadon, R., Bussa, M. P., Spataro, S., Iazzi, F., Lavagno, A., Martin, A., Akram, A., Calen, H., Ikegami Andersson, W., Johansson, T., Kupsc, A., Marciniewski, P., Papenbrock, M., Regina, J., Schönning, K., Wolke, M., Diaz, J., Pothodi Chackara, V., Chlopik, A., Kesik, G., Melnychuk, D., Tarasiuk, J., Wojciechowski, M., Wronka, S., Zwieglinski, B., Amsler, C., Bühler, P., Kratochwil, N., Marton, J., Nalti, W., Steinschaden, D., Widmann, E., Zimmermann, S., and Zmeskal, J.

Published
2021
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39. Study of excited ΞP¯ baryons with the ΞP¯ANDA detector

Author

Barucca, G., Davì, F., Lancioni, G., Mengucci, P., Montalto, L., Natali, P. P., Paone, N., Rinaldi, D., Scalise, L., Krusche, B., Steinacher, M., Liu, Z., Liu, C., Liu, B., Shen, X., Sun, S., Zhao, G., Zhao, J., Albrecht, M., Alkakhi, W., Bökelmann, S., Coen, S., Feldbauer, F., Fink, M., Frech, J., Freudenreich, V., Fritsch, M., Grochowski, J., Hagdorn, R., Heinsius, F. H., Held, T., Holtmann, T., Keshk, I., Koch, H., Kopf, B., Kümmel, M., Küßner, M., Li, J., Linzen, L., Maldaner, S., Oppotsch, J., Pankonin, S., Pelizä, M., Pflüger, S., Reher, J., Reicherz, G., Schnier, C., Steinke, M., Triffterer, T., Wenzel, C., Wiedner, U., Denizli, H., Er, N., Keskin, U., Yerlikaya, S., Yilmaz, A., Beck, R., Chauhan, V., Hammann, C., Hartmann, J., Ketzer, B., Müllers, J., Salisbury, B., Schmidt, C., Thoma, U., Urban, M., Bianconi, A., Bragadireanu, M., Pantea, D., Domagala, M., Filo, G., Lisowski, E., Lisowski, F., Michałek, M., Poznański, P., Płażek, J., Korcyl, K., Lebiedowicz, P., Pysz, K., Schäfer, W., Szczurek, A., Firlej, M., Fiutowski, T., Idzik, M., Moron, J., Swientek, K., Terlecki, P., Korcyl, G., Lalik, R., Malige, A., Moskal, P., Nowakowski, K., Przygoda, W., Rathod, N., Salabura, P., Smyrski, J., Augustin, I., Böhm, R., Lehmann, I., Schmitt, L., Varentsov, V., Al-Turany, M., Belias, A., Deppe, H., Dzhygadlo, R., Flemming, H., Gerhardt, A., Götzen, K., Heinz, A., Jiang, P., Karabowicz, R., Koch, S., Kurilla, U., Lehmann, D., Lühning, J., Lynen, U., Orth, H., Peters, K., Schepers, G., Schmidt, C. J., Schwarz, C., Schwiening, J., Täschner, A., Traxler, M., Voss, B., Wieczorek, P., Abazov, V., Alexeev, G., Barabanov, M. Yu., Dodokhov, V. Kh., Efremov, A., Fechtchenko, A., Galoyan, A., Golovanov, G., Koshurnikov, E. K., Lobanov, Y. Yu., Olshevskiy, A. G., Piskun, A. A., Samartsev, A., Shimanski, S., Skachkov, N. B., Skachkova, A. N., Strokovsky, E. A., Tokmenin, V., Uzhinsky, V., Verkheev, A., Vodopianov, A., Zhuravlev, N. I., Watts, D., Böhm, M., Eyrich, W., Lehmann, A., Miehling, D., Pfaffinger, M., Seth, K., Xiao, T., Ali, A., Hamdi, A., Himmelreich, M., Krebs, M., Nakhoul, S., Nerling, F., Gianotti, P., Lucherini, V., Bracco, G., Bodenschatz, S., Brinkmann, K. T., Brück, L., Diehl, S., Dormenev, V., Düren, M., Erlen, T., Hahn, C., Hayrapetyan, A., Hofmann, J., Kegel, S., Khalid, F., Köseoglu, I., Kripko, A., Kühn, W., Metag, V., Moritz, M., Nanova, M., Novotny, R., Orsich, P., Pereira-de-Lira, J., Sachs, M., Schmidt, M., Schubert, R., Strickert, M., Wasem, T., Zaunick, H. G., Tomasi-Gustafsson, E., Glazier, D., Ireland, D., Seitz, B., Kappert, R., Kavatsyuk, M., Loehner, H., Messchendorp, J., Rodin, V., Kalita, K., Huang, G., Liu, D., Peng, H., Qi, H., Sun, Y., Zhou, X., Kunze, M., Azizi, K., Olgun, A. T., Tavukoglu, Z., Derichs, A., Dosdall, R., Esmail, W., Gillitzer, A., Goldenbaum, F., Grunwald, D., Jokhovets, L., Kannika, J., Kulessa, P., Orfanitski, S., Pérez-Andrade, G., Prasuhn, D., Prencipe, E., Pütz, J., Ritman, J., Rosenthal, E., Schadmand, S., Schmitz, R., Scholl, A., Sefzick, T., Serdyuk, V., Stockmanns, T., Veretennikov, D., Wintz, P., Wüstner, P., Xu, H., Zhou, Y., Cao, X., Hu, Q., Liang, Y., Rigato, V., Isaksson, L., Achenbach, P., Corell, O., Denig, A., Distler, M., Hoek, M., Lauth, W., Leithoff, H. H., Merkel, H., Müller, U., Petersen, J., Pochodzalla, J., Schlimme, S., Sfienti, C., Thiel, M., Bleser, S., Bölting, M., Capozza, L., Dbeyssi, A., Ehret, A., Klasen, R., Kliemt, R., Maas, F., Motzko, C., Noll, O., Piñeiro, D. Rodríguez, Schupp, F., Steinen, M., Wolff, S., Zimmermann, I., Kazlou, D., Korzhik, M., Missevitch, O., Balanutsa, P., Chernetsky, V., Demekhin, A., Dolgolenko, A., Fedorets, P., Gerasimov, A., Golubev, A., Kantsyrev, A., Kirin, D. Y., Kristi, N., Ladygina, E., Luschevskaya, E., Matveev, V. A., Panjushkin, V., Stavinskiy, A. V., Balashoff, A., Boukharov, A., Bukharova, M., Malyshev, O., Vishnevsky, E., Bonaventura, D., Brand, P., Hetz, B., Hüsken, N., Kellers, J., Khoukaz, A., Klostermann, D., Mannweiler, C., Vestrick, S., Bumrungkoh, D., Herold, C., Khosonthongkee, K., Kobdaj, C., Limphirat, A., Manasatitpong, K., Nasawad, T., Pongampai, S., Simantathammakul, T., Srisawad, P., Wongprachanukul, N., Yan, Y., Yu, C., Zhang, X., Zhu, W., Antokhin, E., Barnyakov, A. Yu., Beloborodov, K., Blinov, V. E., Kuyanov, I. A., Pivovarov, S., Pyata, E., Tikhonov, Y., Blinov, A. E., Kononov, S., Kravchenko, E. A., Lattery, M., Boca, G., Duda, D., Finger, M., Finger, Jr., M., Kveton, A., Pesek, M., Peskova, M., Prochazka, I., Slunecka, M., Volf, M., Gallus, P., Jary, V., Korchak, O., Marcisovsky, M., Neue, G., Novy, J., Tomasek, L., Tomasek, M., Virius, M., Vrba, V., Abramov, V., Bukreeva, S., Chernichenko, S., Derevschikov, A., Ferapontov, V., Goncharenko, Y., Levin, A., Maslova, E., Melnik, Y., Meschanin, A., Minaev, N., Mochalov, V., Moiseev, V., Morozov, D., Nogach, L., Poslavskiy, S., Ryazantsev, A., Ryzhikov, S., Semenov, P., Shein, I., Uzunian, A., Vasiliev, A., Yakutin, A., Belostotski, S., Fedotov, G., Izotov, A., Manaenkov, S., Miklukho, O., Preston, M., Tegner, P. E., Wölbing, D., Cederwall, B., Gandhi, K., Rai, A. K., Godre, S., Crede, V., Dobbs, S., Eugenio, P., Calvo, D., De Remigis, P., Filippi, A., Mazza, G., Wheadon, R., Iazzi, F., Lavagno, A., Bussa, M. P., Spataro, S., Akram, A., Calen, H., Ikegami Andersson, W., Johansson, T., Kupsc, A., Marciniewski, P., Papenbrock, M., Regina, J., Rieger, J., Schönning, K., Wolke, M., Chlopik, A., Kesik, G., Melnychuk, D., Tarasiuk, J., Wronka, S., Zwieglinski, B., Amsler, C., Bühler, P., Marton, J., and Zimmermann, S.

Published
2021
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40. Size scaling of the addition spectra in silicon quantum dots

Author

Bohm, M., Hofheinz, M., Jehl, X., Sanquer, M., Vinet, M., Previtali, B., Fraboulet, D., Mariolle, D., and Deleonibus, S.

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics, Condensed Matter - Strongly Correlated Electrons
Abstract

We investigate small artificial quantum dots obtained by geometrically controlled resistive confinement in low mobility silicon-on-insulator nanowires. Addition spectra were recorded at low temperature for various dot areas fixed by lithography. We compare the standard deviation of the addition spectra with theory in the high electron concentration regime. We find that the standard deviation scales as the inverse area of the dot and its absolute value is comparable to the energy spacing of the one particle spectrum., Comment: 4 pages, 5 figures

Published
2004
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45. Feasibility studies for the measurement of time-like proton electromagnetic form factors from p¯p→μ+μ-P¯ANDA at p¯p→μ+μ-P¯ANDA at FAIR

Author

Barucca, G., Davì, F., Lancioni, G., Mengucci, P., Montalto, L., Natali, P. P., Paone, N., Rinaldi, D., Scalise, L., Erni, W., Krusche, B., Steinacher, M., Walford, N., Cao, N., Liu, Z., Liu, C., Liu, B., Shen, X., Sun, S., Tao, J., Xiong, X. A., Zhao, G., Zhao, J., Albrecht, M., Alkakhi, W., Bökelmann, S., Coen, S., Feldbauer, F., Fink, M., Frech, J., Freudenreich, V., Fritsch, M., Grochowski, J., Hagdorn, R., Heinsius, F. H., Held, T., Holtmann, T., Keshk, I., Koch, H., Kopf, B., Kuhlmann, M., Kümmel, M., Küßner, M., Li, J., Linzen, L., Maldaner, S., Oppotsch, J., Pankonin, S., Pelizäus, M., Pflüger, S., Pitka, A., Reher, J., Reicherz, G., Schnier, C., Steinke, M., Triffterer, T., Wenzel, C., Wiedner, U., Denizli, H., Er, N., Keskin, U., Olgun, A. T., Yerlikaya, S., Yilmaz, A., Beck, R., Hammann, C., Hartmann, J., Ketzer, B., Müllers, J., Rossbach, M., Salisbury, B., Schmidt, C., Thoma, U., Urban, M., Bianconi, A., Bragadireanu, M., Pantea, D., Domagala, M., Filo, G., Lisowski, E., Lisowski, F., Michałek, M., Poznański, P., Płażek, J., Korcyl, K., Kozela, A., Lebiedowicz, P., Pysz, K., Schäfer, W., Szczurek, A., Firlej, M., Fiutowski, T., Idzik, M., Moron, J., Swientek, K., Terlecki, P., Korcyl, G., Lalik, R., Malige, A., Moskal, P., Nowakowski, K., Przygoda, W., Rathod, N., Rudy, Z., Salabura, P., Smyrski, J., Augustin, I., Böhm, R., Lehmann, I., Schmitt, L., Varentsov, V., Al-Turany, M., Belias, A., Deppe, H., Dzhygadlo, R., Flemming, H., Gerhardt, A., Götzen, K., Heinz, A., Jiang, P., Karabowicz, R., Koch, S., Kurilla, U., Lehmann, D., Lühning, J., Lynen, U., Orth, H., Peters, K., Saito, T., Schepers, G., Schmidt, C. J., Schwarz, C., Schwiening, J., Täschner, A., Traxler, M., Voss, B., Wieczorek, P., Abazov, V., Alexeev, G., Arefiev, V. A., Astakhov, V., Barabanov, M. Yu., Batyunya, B. V., Dodokhov, V. Kh., Efremov, A., Fechtchenko, A., Galoyan, A., Golovanov, G., Koshurnikov, E. K., Lobanov, Y. Yu., Olshevskiy, A. G., Piskun, A. A., Samartsev, A., Shimanski, S., Skachkov, N. B., Skachkova, A. N., Strokovsky, E. A., Tokmenin, V., Uzhinsky, V., Verkheev, A., Vodopianov, A., Zhuravlev, N. I., Branford, D., Watts, D., Böhm, M., Eyrich, W., Lehmann, A., Miehling, D., Pfaffinger, M., Quin, N., Robison, L., Seth, K., Xiao, T., Bettoni, D., Ali, A., Hamdi, A., Himmelreich, M., Krebs, M., Nakhoul, S., Nerling, F., Belousov, A., Kisel, I., Kozlov, G., Pugach, M., Zyzak, M., Bianchi, N., Gianotti, P., Lucherini, V., Bracco, G., Bettner, Y., Bodenschatz, S., Brinkmann, K. T., Brück, L., Diehl, S., Dormenev, V., Düren, M., Erlen, T., Föhl, K., Hahn, C., Hayrapetyan, A., Hofmann, J., Kegel, S., Kesselkaul, M., Köseoglu, I., Kripko, A., Kühn, W., Lange, J. S., Metag, V., Moritz, M., Nanova, M., Novotny, R., Orsich, P., Pereira-de-Lira, J., Peter, M., Sachs, M., Schmidt, M., Schubert, R., Stenzel, H., Straube, M., Strickert, M., Thöring, U., Wasem, T., Wohlfahrt, B., Zaunick, H. G., Tomasi-Gustafsson, E., Glazier, D., Ireland, D., Seitz, B., Deepak, P. N., Kulkarni, A., Kappert, R., Kavatsyuk, M., Loehner, H., Messchendorp, J., Rodin, V., Schakel, P., Vejdani, S., Dutta, K., Kalita, K., Huang, G., Liu, D., Peng, H., Qi, H., Sun, Y., Zhou, X., Kunze, M., Azizi, K., Tavukoglu, Z., Derichs, A., Dosdall, R., Esmail, W., Gillitzer, A., Goldenbaum, F., Grunwald, D., Jokhovets, L., Kannika, J., Kulessa, P., Orfanitski, S., Pérez Andrade, G., Prasuhn, D., Prencipe, E., Pütz, J., Ritman, J., Rosenthal, E., Schadmand, S., Schmitz, R., Scholl, A., Sefzick, T., Serdyuk, V., Stockmanns, T., Veretennikov, D., Wintz, P., Wüstner, P., Xu, H., Zhou, Y., Cao, X., Hu, Q., Li, Z., Li, H., Liang, Y., Ma, X., Rigato, V., Isaksson, L., Achenbach, P., Corell, O., Denig, A., Distler, M., Hoek, M., Lauth, W., Leithoff, H. H., Liu, Z., Merkel, H., Müller, U., Pochodzalla, J., Schlimme, S., Sfienti, C., Thiel, M., Zambrana, M., Ahmed , S., Bleser, S., Bölting, M., Capozza, L., Dbeyssi, A., Ehret, A., Klasen, R., Kliemt, R., Maas, F., Motzko, C., Noll, O., Piñeiro, D. Rodríguez, Schupp, F., Steinen, M., Wolff, S., Zimmermann, I., Fedorov, A., Kazlou, D., Korzhik, M., Missevitch, O., Balanutsa, P., Chernetsky, V., Demekhin, A., Dolgolenko, A., Fedorets, P., Gerasimov, A., Golubev, A., Goryachev, V., Kantsyrev, A., Kirin, D. Y., Kristi, N., Ladygina, E., Luschevskaya, E., Matveev, V. A., Panjushkin, V., Stavinskiy, A. V., Balashoff, A., Boukharov, A., Malyshev, O., Basant, K. N., Kumawat, H., Roy, B., Saxena, A., Yogesh, S., Bonaventura, D., Brand, P., Fritzsch, C., Grieser, S., Hargens, C., Hergemöller, A. K., Hetz, B., Hüsken, N., Kellers, J., Khoukaz, A., Mannweiler, C., Vestrick, S., Bumrungkoh, D., Herold, C., Khosonthongkee, K., Kobdaj, C., Limphirat, A., Manasatitpong, K., Nasawad, T., Pongampai, S., Simantathammakul, T., Srisawad, P., Wongprachanukul, N., Yan, Y., Yu, C., Zhang, X., Zhu, W., Blinov, A. E., Kononov, S., Kravchenko, E. A., Antokhin, E., Barnyakov, A. Yu., Beloborodov, K., Blinov, V. E., Kuyanov, I. A., Pivovarov, S., Pyata, E., Tikhonov, Y., Hunter, G., Lattery, M., Pace, H., Boca, G., Duda, D., Finger, M., Finger, Jr., M., Kveton, A., Pesek, M., Peskova, M., Prochazka, I., Slunecka, M., Volf, M., Gallus, P., Jary, V., Korchak, O., Marcisovsky, M., Neue, G., Novy, J., Tomasek, L., Tomasek, M., Virius, M., Vrba, V., Abramov, V., Bukreeva, S., Chernichenko, S., Derevschikov, A., Ferapontov, V., Goncharenko, Y., Levin, A., Maslova, E., Melnik, Y., Meschanin, A., Minaev, N., Mochalov, V., Moiseev, V., Morozov, D., Nogach, L., Poslavskiy, S., Ryazantsev, A., Ryzhikov, S., Semenov, P., Shein, I., Uzunian, A., Vasiliev, A., Yakutin, A., Roy, U., Yabsley, B., Belostotski, S., Fedotov, G., Gavrilov, G., Izotov, A., Manaenkov, S., Miklukho, O., Zhdanov, A., Atac, A., Bäck, T., Cederwall, B., Makonyi, K., Preston, M., Tegner, P. E., Wölbing, D., Gandhi, K., Rai, A. K., Godre, S., Crede, V., Dobbs, S., Eugenio, P., Lersch, D., Calvo, D., De Remigis, P., Filippi, A., Mazza, G., Rivetti, A., Wheadon, R., Bussa, M. P., Spataro, S., Iazzi, F., Lavagno, A., Martin, A., Akram, A., Calen, H., Andersson, W. Ikegami, Johansson, T., Kupsc, A., Marciniewski, P., Papenbrock, M., Regina, J., Rieger, J., Schönning, K., Wolke, M., Pothodi Chackara, V., Chlopik, A., Kesik, G., Melnychuk, D., Tarasiuk, J., Wojciechowski, M., Wronka, S., Zwieglinski, B., Amsler, C., Bühler, P., Marton, J., Nalti, W., Steinschaden, D., Widmann, E., Zimmermann, S., and Zmeskal, J.

Published
2021
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47. Low‐level HIV viraemia during antiretroviral therapy: Longitudinal patterns and predictors of viral suppression.

Author

Elén, S., Björkman, P., Zazzi, M., Böhm, M., Bernal, E., Sönnerborg, A., and Elvstam, O.

Subjects
HIV infections, STATISTICS, CONFIDENCE intervals, MULTIPLE regression analysis, VIRAL load, ANTIRETROVIRAL agents, VIREMIA, ODDS ratio, LONGITUDINAL method
Abstract

Objectives: Our objective was to characterize longitudinal patterns of viraemia and factors associated with viral suppression in people with HIV and low‐level viraemia (LLV) during antiretroviral therapy (ART). Methods: We included people with HIV in the EuResist Integrated Database with LLV following ART initiation after 2005. LLV was defined as two or more consecutive viral load (VL) measurements of 51–199 copies/mL 30–365 days apart after >12 months of ART. Viraemia patterns were analyzed over 24 months. Factors associated with viral suppression at 12 months after LLV episodes were identified using univariable and multivariable logistic regression. Results: Of 25 113 people with HIV, 2474 (9.9%) had LLV. Among 1387 participants with 24 months of follow‐up after LLV, 406 (29%) had persistent suppression, 669 (48%) had transient viraemic episodes, 29 (2%) had persistent LLV, and 283 (20%) had virological failure. Following LLV episodes, the proportion with detectable viraemia declined (p for trend <0.001 and 0.034, in the first and second year, respectively). At 12 months, 68% had undetectable VL, which was associated with suppression before LLV (adjusted odds ratio [aOR] 1.7; 95% confidence interval [CI] 1.2–2.4) and ART modification after LLV (aOR 1.6; 95% CI 1.0–2.4). The following factors were negatively associated with undetectable VL at 12 months: higher VL during LLV (aOR 0.57 per log10 copies/mL; 95% CI 0.37–0.89), injecting drug use (aOR 0.67; 95% CI 0.47–0.96), and regimens with protease inhibitors (aOR 0.65; 95% CI 0.49–0.87) or combined anchor drugs (aOR 0.52; 95% CI 0.32–0.85). Conclusion: Most people with LLV did not experience sustained viral suppression during 24‐month follow‐up, supporting the association between LLV and inferior treatment outcome. [ABSTRACT FROM AUTHOR]

Published
2024
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